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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2018 Volume 53 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Liquid biopsy and PCR-free ultrasensitive detection systems in oncology (Review)

Alessia Finotti, Matteo Allegretti, Jessica Gasparello, Patrizio Giacomini, Demetrios A. Spandidos, Giuseppe Spoto, Roberto Gambari
Pages: 1395-1434
Published online on: 06 August 2018

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Review

Novel insights into ion channels in cancer stem cells (Review)

Qijiao Cheng, Anhai Chen, Qian Du, Qiushi Liao, Zhangli Shuai, Changmei Chen, Xinrong Yang, Yaxia Hu, Ju Zhao, Songpo Liu, Guo Rong Wen, Jiaxin An, Hai Jing, Biguang Tuo, Rui Xie, Jingyu Xu
Pages: 1435-1441
Published online on: 24 July 2018

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Article Open Access

Cinnamtannin B-1 inhibits cell survival molecules and induces apoptosis in colon cancer

Patrick P. Carriere, Neeraj Kapur, Hina Mir, Ashley B. Ward, Shailesh Singh
Pages: 1442-1454
Published online on: 19 July 2018

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Article Open Access

Integrative analysis of dysregulated microRNAs and mRNAs in multiple recurrent synchronized renal tumors from patients with von Hippel-Lindau disease

Charles-Henry Gattolliat, Sophie Couvé, Guillaume Meurice, Cédric Oréar, Nathalie Droin, Mathieu Chiquet, Sophie Ferlicot, Virginie Verkarre, Viorel Vasiliu, Vincent Molinié, Arnaud Méjean, Philippe Dessen, Sophie Giraud, Brigitte Bressac-De-Paillerets, Betty Gardie, Bin Tean Teh, Stéphane Richard, Sophie Gad
Pages: 1455-1468
Published online on: 19 July 2018

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Article Open Access

Upregulation of PD‑L1 expression by resveratrol and piceatannol in breast and colorectal cancer cells occurs via HDAC3/p300‑mediated NF‑κB signaling

Justin Lucas, Tze-Chen Hsieh, H. Dorota Halicka, Zbigniew Darzynkiewicz, Joseph M. Wu
Pages: 1469-1480
Published online on: 01 August 2018

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Article Open Access

Translationally controlled tumor protein affects colorectal cancer metastasis through the high mobility group box 1-dependent pathway

Maoliang Huang, Yan Geng, Qiaoting Deng, Ru Li, Xiangyang Shao, Zhigao Zhang, Weiwen Xu, Yingsong Wu, Qiang Ma
Pages: 1481-1492
Published online on: 25 July 2018

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Article Open Access

MicroRNA-488 inhibits proliferation, invasion and EMT in osteosarcoma cell lines by targeting aquaporin 3 Retraction in /10.3892/ijo.2022.5466

Jing Qiu, Yongzhi Zhang, Hu Chen, Zhi Guo
Pages: 1493-1504
Published online on: 16 July 2018

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Article Open Access

miR‑92b promotes autophagy and suppresses viability and invasion in breast cancer by targeting EZH2

Fei Liu, Meixiang Sang, Lingjiao Meng, Lina Gu, Shina Liu, Juan Li, Cuizhi Geng
Pages: 1505-1515
Published online on: 18 July 2018

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Article Open Access

Establishment of three novel cell lines derived from African American patients with colorectal carcinoma: A unique tool for assessing racial health disparity

Jenny Paredes, Ping Ji, Joseph F. Lacomb, Kenneth R. Shroyer, Laura A. Martello, Jennie L. Williams
Pages: 1516-1528
Published online on: 31 July 2018

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Article Open Access

Competing endogenous RNA analysis reveals the regulatory potency of circRNA_036186 in HNSCC

Wen-Long Wang, Zhi Yang, Yi-Juan Zhang, Ping Lu, You-Kang Ni, Chang-Fu Sun, Fa-Yu Liu
Pages: 1529-1543
Published online on: 24 July 2018

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Article Open Access

CX3CL1/fractalkine enhances prostate cancer spinal metastasis by activating the Src/FAK pathway

Peng Liu, Yun Liang, Libo Jiang, Houlei Wang, Shengxing Wang, Jian Dong
Pages: 1544-1556
Published online on: 18 July 2018

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Article Open Access

Downregulation of HOXA3 in lung adenocarcinoma and its relevant molecular mechanism analysed by RT-qPCR, TCGA and in silico analysis

Bin-Liang Gan, Rong-Quan He, Yu Zhang, Dan-Ming Wei, Xiao-Hua Hu, Gang Chen
Pages: 1557-1579
Published online on: 30 July 2018

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Article Open Access

Intraperitoneal neutrophils activated by KRAS-induced ovarian cancer exert antitumor effects by modulating adaptive immunity

Mitsuyo Yoshida, Ayumi Taguchi, Kei Kawana, Juri Ogishima, Katsuyuki Adachi, Akira Kawata, Hiroe Nakamura, Masakazu Sato, Asaha Fujimoto, Tomoko Inoue, Kensuke Tomio, Mayuyo Mori, Takeshi Nagamatsu, Takahide Arimoto, Kaori Koga, Osamu Wada Hiraike, Katsutoshi Oda, Tohru Kiyono, Yutaka Osuga, Tomoyuki Fujii
Pages: 1580-1590
Published online on: 26 July 2018

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Article

Upregulation of miR-96 promotes radioresistance in glioblastoma cells via targeting PDCD4

Pin Guo, Yanan Yu, Zibin Tian, Yingying Lin, Yongming Qiu, Weicheng Yao, Lijuan Zhang
Pages: 1591-1600
Published online on: 23 July 2018

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Article

A miR-26a/E2F7 feedback loop contributes to tamoxifen resistance in ER-positive breast cancer

Jian Liu, Xiang Li, Meng Wang, Guodong Xiao, Ganghua Yang, Huangzhen Wang, Yanbo Li, Xin Sun, Sida Qin, Ning Du, Hong Ren, Yamei Pang
Pages: 1601-1612
Published online on: 19 July 2018

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Article

Effects of β-caryophyllene on arginine ADP-ribosyltransferase 1-mediated regulation of glycolysis in colorectal cancer under high-glucose conditions

Li Zhou, Mu-Lu Zhan, Yi Tang, Ming Xiao, Ming Li, Qing-Shu Li, Lian Yang, Xian Li, Wen-Wen Chen, Ya-Lan Wang
Pages: 1613-1624
Published online on: 27 July 2018

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Article

Inositol hexaphosphate limits the migration and the invasiveness of colorectal carcinoma cells in vitro

Ladislava Schröterová, Alena Ježková, Emil Rudolf, Kateřina Caltová, Věra Králová, Veronika Hanušová
Pages: 1625-1632
Published online on: 19 July 2018

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Article

Clinical significance of growth factor receptor EGFR and angiogenesis regulator VEGF‑R2 in patients with ovarian cancer at FIGO stages I-II

Ingiridur Skirnisdottir, Helena Åkerud, Tomas Seidal
Pages: 1633-1642
Published online on: 31 July 2018

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Article

TRIM2 regulates the development and metastasis of tumorous cells of osteosarcoma

Yi Qin, Jichao  Ye, Fulan Zhao, Shaoyu Hu, Suwei Wang
Pages: 1643-1656
Published online on: 20 July 2018

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Article

2,3,7,8‑Tetrachlorodibenzo‑p‑dioxin suppresses the growth of human liver cancer HepG2 cells in vitro: Involvement of cell signaling factors

Masayoshi Yamaguchi, Oliver Hankinson
Pages: 1657-1666
Published online on: 27 July 2018

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Article

Radiosensitization by irinotecan is attributed to G2/M phase arrest, followed by enhanced apoptosis, probably through the ATM/Chk/Cdc25C/Cdc2 pathway in p53-mutant colorectal cancer cells

Yaqi Wang, Lifeng Yang, Jing Zhang, Menglong Zhou, Lijun Shen, Weijuan Deng, Liping Liang, Ran Hu, Wang Yang, Ye Yao, Hui Zhang, Zhen Zhang
Pages: 1667-1680
Published online on: 03 August 2018

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Article

Anti-adult T‑cell leukemia/lymphoma activity of cerdulatinib, a dual SYK/JAK kinase inhibitor

Chie Ishikawa, Masachika Senba, Naoki Mori
Pages: 1681-1690
Published online on: 01 August 2018

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Article

Transcriptional activation of miR-320a by ATF2, ELK1 and YY1 induces cancer cell apoptosis under ionizing radiation conditions

Zheng Hu, Yi Tie, Guixiang Lv, Jie Zhu, Hanjiang Fu, Xiaofei Zheng
Pages: 1691-1702
Published online on: 23 July 2018

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Article

Modulation of G6PD affects bladder cancer via ROS accumulation and the AKT pathway in vitro

Xiaoyi Chen, Zhijie Xu, Zhijian Zhu, Anqi Chen, Guanghou Fu, Yimin Wang, Hao Pan, Baiye Jin
Pages: 1703-1712
Published online on: 25 July 2018

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Article

Anaplastic transition within the cancer microenvironment in early-stage oral tongue squamous cell carcinoma is associated with local recurrence

Kohei Okuyama, Keiji Suzuki, Souichi Yanamoto, Tomofumi Naruse, Hiroki Tsuchihashi, Shunichi Yamashita, Masahiro Umeda
Pages: 1713-1720
Published online on: 06 August 2018

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Article

Identification of fatal outcome in a childhood nasopharyngeal carcinoma patient by protein expression profiling

Mohamed E.M. Saeed, Rolf Mertens, Rupert Handgretinger, Thomas Efferth
Pages: 1721-1731
Published online on: 19 July 2018

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Article

miR-200b/c targets the expression of RhoE and inhibits the proliferation and invasion of non-small cell lung cancer cells Corrigendum in /10.3892/ijo.2022.5432

Qiulin Tang, Mingxing Li, Liang Chen, Feng Bi, Hongwei Xia
Pages: 1732-1742
Published online on: 20 July 2018

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Article

The tumorigenic role of DSPP and its potential regulation of the unfolded protein response and ER stress in oral cancer cells

Ioannis Gkouveris, Nikolaos G. Nikitakis, Jaya Aseervatham, Kalu U.E. Ogbureke
Pages: 1743-1751
Published online on: 16 July 2018

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Article

Circular RNA‑MTO1 suppresses breast cancer cell viability and reverses monastrol resistance through regulating the TRAF4/Eg5 axis

Yunxiao Liu, Yanyan Dong, Liping Zhao, Lihong Su, Jin Luo
Pages: 1752-1762
Published online on: 17 July 2018

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Article

Knockdown of TWIST enhances the cytotoxicity of chemotherapeutic drugs in doxorubicin-resistant HepG2 cells by suppressing MDR1 and EMT

Rong Li, Changli Wu, Hongying Liang, Yinghai Zhao, Chunyan Lin, Xiujuan Zhang, Caiguo Ye
Pages: 1763-1773
Published online on: 20 July 2018

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Article

Lewis(y) antigen-mediated positive feedback loop induces and promotes chemotherapeutic resistance in ovarian cancer

Juanjuan Liu, Mingjun Zheng, Yue Qi, Huimin Wang, Miao Liu, Qing Liu, Bei Lin
Pages: 1774-1786
Published online on: 20 July 2018

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Article

Exogenous expression of miRNA-3613-3p causes APAF1 downregulation and affects several proteins involved in apoptosis in BE(2)-C human neuroblastoma cells

Iwona Nowak, Elżbieta Boratyn, Małgorzata Durbas, Irena Horwacik, Hanna Rokita
Pages: 1787-1799
Published online on: 31 July 2018

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Article

MicroRNA-552 links Wnt signaling to p53 tumor suppressor in colorectal cancer

Bomi Kwak, Dong Uk Kim, Tae Oh Kim, Heui-Soo Kim, Sang-Woo Kim
Pages: 1800-1808
Published online on: 26 July 2018

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Article

Interleukin‑17A and heparanase promote angiogenesis and cell proliferation and invasion in cervical cancer

Qiongying Lv, Kejia Wu, Fulin Liu, Wanrong Wu, Yurou Chen, Wei Zhang
Pages: 1809-1817
Published online on: 26 July 2018

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Journal Cover
October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

MicroRNA regulation of macrophage polarization in lung cancer: Regulatory networks and therapeutic potential (Review)

Zhao Yiming, Li Jie
Article Number: 121
Published online on: 02 September 2026

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Article Open Access

Effect of xeroderma pigmentosum group C on the characteristics and regulatory mechanisms of lung cancer stem cells

Ben Yang, Yang Yang, Weiyu Wang, Yubing Wang, Huaijie Wang, Liya Qin, Yongming Wang, Sipeng Sun, Shubo Wang, Meihua Qu
Article Number: 120
Published online on: 01 September 2026

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Review Open Access

Post‑translational modification‑governed immune states in cancer immunity: Biomarker implications for checkpoint competence, tumor visibility and immunotherapy resistance (Review)

Jinghao Pan, Boyang Li, Ruonan Lin, Chenlu Fang, Lucy Yue Lau, Zehao Hong, Yi Chen
Article Number: 119
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy

Michal Pastorek, Veronika Simko, Martina Takacova, Monika Barathova, Maria Bartosova, Luba Hunakova, Olga Sedlakova, Sona Hudecova, Olga Krizanova, Franck Dequiedt, Silvia Pastorekova, Jan Sedlak
Article Number: 118
Published online on: 20 August 2026

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Article Open Access

Single in situ intratumoral low‑dose shikonin hydrogel plus mild photothermal therapy elicits systemic antitumor immunity in immune‑cold triple‑negative breast cancer

Tao Pan, Zujian Feng, Ting Shang, Jun Jiang, Fang Zhang
Article Number: 117
Published online on: 19 August 2026

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Article Open Access

KIAA1429 knockdown alleviates osteosarcoma  progression by destabilizing SLC7A11 mRNA via m6A methylation to promote ferroptosis

Hui Zeng, Yunyan Zhong, Dingbiao Zeng, Shiliang Xiao, Song Zou
Article Number: 116
Published online on: 17 August 2026

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Correction Open Access

[Corrigendum] Tanshinone I effectively induces apoptosis in estrogen receptor‑positive (MCF‑7) and estrogen receptor‑negative (MDA‑MB‑231) breast cancer cells

Irina Tsoy Nizamutdinova, Gyeong Won Lee, Kun Ho Son, Su Jin Jeon, Sam Sik Kang, Yeong Shik Kim, Jae Heun Lee, Han Geuk Seo, Ki Churl Chang, Hye Jung Kim
Article Number: 115
Published online on: 12 August 2026

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Review Open Access

Signaling pathways and targeted therapy in high‑risk refractory thyroid cancer: From bench to bedside (Review)

Jian Wang, Zhi Liu, Qing Zhang, Wei Sun
Article Number: 114
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Downmodulation of dimethyl transferase activity enhances tumor necrosis factor‑related apoptosis‑inducing ligand‑ induced apoptosis in prostate cancer cells

Claudio Festuccia, Giovanni Luca Gravina, Anna Maria D'Alessandro, Danilo Millimaggi, Cristiana Di Rocco, Vincenza Dolo, Enrico Ricevuto, Carlo Vicentini, Mauro Bologna
Article Number: 113
Published online on: 10 August 2026

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Review Open Access

The pivotal role of SCD1 in digestive cancers: Bridging lipid metabolic reprogramming and programmed cell death (Review)

Yangxi Fu, Zheng Wang, Lin Liu, Xudong Tang
Article Number: 112
Published online on: 07 August 2026

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Article Open Access

piR‑164552 promotes malignant progression in head and neck squamous cell carcinoma via the RBM4/EIF4E2 signaling axis: Insights from multi‑omics and functional analyses

Shan Yang, Zhen Shang, Shunxian Xia, Hongbo Liu, Yanhan Dong, Xiaomin Wang, Wenhua Xu, Haijun Lu
Article Number: 111
Published online on: 07 August 2026

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Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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Journal Cover
November-2026 Volume 69 Issue 5

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] In vitro modulation of MMP‑2 and MMP‑9 in adult human sarcoma cell lines by cytokines, inducers and inhibitors

M.W. Roomi, T. Kalinovsky, J.  Monterrey, M. Rath, A. Niedzwiecki
Article Number: 129
Published online on: 21 September 2026

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Review Open Access

Eomesodermin in renal cell carcinoma: Epigenetic and immune crosstalk driving tumor progression (Review)

Zhifei Che, Dongwen Huang, Jiaming Lin, Xincen Wang, Rongjin Feng, Xianping Che, Yubin Wang
Article Number: 128
Published online on: 18 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ultraviolet exposure of melanoma cells induces fibroblast activation protein‑α in fibroblasts: Implications for melanoma invasion

Petra Wäster, Inger Rosdahl, Brendan F.  Gilmore, Oliver Seifert
Article Number: 127
Published online on: 16 September 2026

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Article Open Access

E3 ubiquitin ligase MAGI3‑mediated TAZ ubiquitination suppresses the non‑small cell lung cancer occurrence and development by targeting the Wnt pathway

Ye Liang, Jie Zhuang
Article Number: 126
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex

Tanveer Ahmad, Waseem Ashraf, Abdulkhaleg Ibrahim, Liliyana Zaayter, Christian D. Muller, Ali Hamiche, Yves Mély, Christian Bronner, Marc Mousli
Article Number: 125
Published online on: 14 September 2026

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Correction Open Access

[Corrigendum] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Peiyu Pu, Chunsheng Kang
Article Number: 124
Published online on: 03 September 2026

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Review Open Access

Dendritic cell‑based vaccines for colorectal cancer: Mechanisms, clinical progress and future directions (Review)

Lian Yih Pong, Siti Ayuni Hassanudin, Seng Kong Tham, Ravichandran Manickam, Chee Yin Wong, Keat Seong Poh, Chit Laa Poh
Article Number: 123
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Pro‑metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 122
Published online on: 02 September 2026

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