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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2019 Volume 54 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Cancer-associated stroke: Pathophysiology, detection and management (Review)

Efthimios Dardiotis, Athina-Maria Aloizou, Sofia Markoula, Vasileios Siokas, Konstantinos Tsarouhas, Georgios Tzanakakis, Massimo Libra, Athanassios P. Kyritsis, Alexandros G. Brotis, Michael Aschner, Illana Gozes, Dimitrios P. Bogdanos, Demetrios A. Spandidos, Panayiotis D. Mitsias, Aristidis Tsatsakis
Pages: 779-796
Published online on: 02 January 2019

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Review

Roles of FGF8 subfamily in embryogenesis and oral‑maxillofacial diseases (Review)

Yilong Hao, Shuya Tang, Yao Yuan, Rui Liu, Qianming Chen
Pages: 797-806
Published online on: 07 January 2019

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Article Open Access

MicroRNA‑98 suppresses cell growth and invasion of retinoblastoma via targeting the IGF1R/k‑Ras/Raf/MEK/ERK signaling pathway

Long Guo, Yu Bai, Shuzhe Ji, Hong Ma
Pages: 807-820
Published online on: 17 January 2019

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Article Open Access

Hsp70 (HSP70A1A) downregulation enhances the metastatic ability of cancer cells

Panagiota Kasioumi, Paraskevi Vrazeli, Patra Vezyraki, Stelios Zerikiotis, Christos Katsouras, Alexander Damalas, Charalampos Angelidis
Pages: 821-832
Published online on: 12 December 2018

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Article Open Access

Carboxypeptidase A4 accumulation is associated with an aggressive phenotype and poor prognosis in triple-negative breast cancer

Tadashi Handa, Ayaka Katayama, Takehiko Yokobori, Arito Yamane, Takaaki Fujii, Sayaka Obayashi, Sasagu Kurozumi, Reika Kawabata-Iwakawa, Navchaa Gombodorj, Masahiko Nishiyama, Takayuki Asao, Ken Shirabe, Hiroyuki Kuwano, Tetsunari Oyama
Pages: 833-844
Published online on: 04 January 2019

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Article Open Access

miR‑3664‑5P suppresses the proliferation and metastasis of gastric cancer by attenuating the NF‑κB signaling pathway through targeting MTDH

Yuwen Jiao, Haojun Yang, Jun Qian, Yu Gong, Hanyang Liu, Siyuan Wu, Liang Cao, Liming Tang
Pages: 845-858
Published online on: 08 January 2019

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Article Open Access

A novel splice mutation induces exon skipping of the EXT1 gene in patients with hereditary multiple exostoses

Xiaoyan Guo, Mingrui Lin, Wei Yan, Wenxu Chen, Guolin Hong
Pages: 859-868
Published online on: 16 January 2019

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Article Open Access

Arsenic‑induced BRCA1 CpG promoter methylation is associated with the downregulation of ERα and resistance to tamoxifen in MCF7 breast cancer cells and mouse mammary tumor xenografts

Ornella I. Selmin, Micah G. Donovan, Bethany Skovan, Gillian D. Paine‑Murieta, Donato F. Romagnolo
Pages: 869-878
Published online on: 15 January 2019

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Article Open Access

Bile acids promote gastric intestinal metaplasia by upregulating CDX2 and MUC2 expression via the FXR/NF-κB signalling pathway

Jun-Hui Yu, Jian-Bao Zheng, Jie Qi, Kui Yang, Yun-Hua Wu, Kai Wang, Chun-Bao Wang, Xue-Jun Sun
Pages: 879-892
Published online on: 22 January 2019

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Article Open Access

Sphere‑forming assay vs. organoid culture: Determining long‑term stemness and the chemoresistant capacity of primary colorectal cancer cells

Hui Zhao, Chang Yan, Yibing Hu, Lei Mu, Kaiyu Huang, Qiling Li, Xiaolan Li, Deding Tao, Jichao Qin
Pages: 893-904
Published online on: 11 January 2019

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Article Open Access

Fe3O4-solamargine induces apoptosis and inhibits metastasis of pancreatic cancer cells Retraction in /10.3892/ijo.2024.5657

Xiaodong Xie, Xiuming Zhang, Jun Chen, Xun Tang, Meiqin Wang, Lei Zhang, Zhen Guo, Wenrong Shen
Pages: 905-915
Published online on: 19 November 2018

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Article Open Access

Penicillin‑binding protein 1A mutation‑positive Helicobacter pylori promotes epithelial‑mesenchymal transition in gastric cancer via the suppression of microRNA‑134

Lu Huang, Zhi‑Yong Wang, Dao‑Dong Pan
Pages: 916-928
Published online on: 12 December 2018

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Article Open Access

lncRNA H19 promotes viability and epithelial-mesenchymal transition of lung adenocarcinoma cells by targeting miR-29b-3p and modifying STAT3

Lihua Liu, Linlin Liu, Sijing Lu
Pages: 929-941
Published online on: 24 January 2019

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Article Open Access

CP‑31398 attenuates endometrial cancer cell invasion, metastasis and resistance to apoptosis by downregulating MDM2 expression

Ling Liu, Li Yang, Hui Chang, Yan‑Nan Chen, Feng Zhang, Shuo Feng, Juan Peng, Chen‑Chen Ren, Xiao‑An Zhang
Pages: 942-954
Published online on: 09 January 2019

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Article Open Access

Muscleblind‑like 1 destabilizes Snail mRNA and suppresses the metastasis of colorectal cancer cells via the Snail/E‑cadherin axis

Liang Tang, Peng Zhao, Dalu Kong
Pages: 955-965
Published online on: 18 January 2019

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Article Open Access

25-HC decreases the sensitivity of human gastric cancer cells to 5-fluorouracil and promotes cells invasion via the TLR2/NF-κB signaling pathway

Saisai Wang, Yuanyuan Yao, Chunhui Rao, Gang Zheng, Wenbin Chen
Pages: 966-980
Published online on: 11 January 2019

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Article

Eya2 is critical for the E2A‑HLF‑mediated immortalization of mouse hematopoietic stem/progenitor cells

Bishnu Devi Maharjan, Ryoichi Ono, Tetsuya Nosaka
Pages: 981-990
Published online on: 03 January 2019

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Article

MicroRNA-200b and -301 are associated with gemcitabine response as biomarkers in pancreatic carcinoma cells

Naotake Funamizu, Curtis Ray Lacy, Minori Kamada, Katsuhiko Yanaga, Yoshinobu Manome
Pages: 991-1000
Published online on: 07 January 2019

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Article Open Access

Involvement of MAF1 homolog, negative regulator of RNA polymerase III in colorectal cancer progression

Kentaro Hokonohara, Naohiro Nishida, Norikatsu Miyoshi, Hidekazu Takahashi, Naotsugu Haraguchi, Taishi Hata, Chu Matsuda, Tsunekazu Mizushima, Yuichiro Doki, Masaki Mori
Pages: 1001-1009
Published online on: 07 January 2019

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Article

The Wnt modulator ICG‑001 mediates the inhibition of nasopharyngeal carcinoma cell migration in vitro via the miR‑150/CD44 axis

Lai‑Sheung Chan, On‑Ying Man, Hoi‑Hin Kwok, Luo Chen, King‑Chi Chan, Hong‑Lok Lung, Roger Kai‑Cheong Ngan, Ricky Ngok‑Shun Wong, Kwok‑Wai Lo, Anne Wing‑Mui Lee, George Sai‑Wah Tsao, Michael Kahn, Maria Li Lung, Nai‑Ki Mak
Pages: 1010-1020
Published online on: 12 December 2018

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Article

DKK3 knockdown confers negative effects on the malignant potency of head and neck squamous cell carcinoma cells via the PI3K/Akt and MAPK signaling pathways

Naoki Katase, Shin‑Ichiro Nishimatsu, Akira Yamauchi, Masahiro Yamamura, Shuichi Fujita
Pages: 1021-1032
Published online on: 14 December 2018

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Article

Long non‑coding RNA UCA1 confers tamoxifen resistance in breast cancer endocrinotherapy through regulation of the EZH2/p21 axis and the PI3K/AKT signaling pathway10.3892/ijo.2024.5611

Zhuo Li, Dehai Yu, Haijun Li, You Lv, Sijie Li
Pages: 1033-1042
Published online on: 08 January 2019

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Article

Long non‑coding RNA FOXD2‑AS1/miR‑150‑5p/PFN2 axis regulates breast cancer malignancy and tumorigenesis

Ming Jiang, Ni Qiu, Haoming Xia, Hongling Liang, Hongsheng Li, Xiang Ao
Pages: 1043-1052
Published online on: 03 January 2019

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Article

shRNA‑mediated knockdown of KNTC1 suppresses cell viability and induces apoptosis in esophageal squamous cell carcinoma

Chun‑Tao Liu, Li Min, Yong‑Jun Wang, Peng Li, Yong‑Dong Wu, Shu‑Tian Zhang
Pages: 1053-1060
Published online on: 03 January 2019

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Article

Inhibition of multiple myeloma‑derived exosomes uptake suppresses the functional response in bone marrow stromal cell

Yongjiang Zheng, Chenggong Tu, Jingwen Zhang, Jinheng Wang
Pages: 1061-1070
Published online on: 11 January 2019

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Article

Profiling of apoptosis- and autophagy-associated molecules in human lung cancer A549 cells in response to cisplatin treatment using stable isotope labeling with amino acids in cell culture

Zongqiang Wang, Guifeng Liu, Jinlan Jiang
Pages: 1071-1085
Published online on: 18 January 2019

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Article

Stathmin gene silencing suppresses proliferation, migration and invasion of gastric cancer cells via AKT/sCLU and STAT3 signaling

Feng Shu, Xiaoqin Zou, Huan Tuo, Sha She, Juan Huang, Hong Ren, Huaidong Hu, Shifang Peng, Jiandong Wang, Yixuan Yang
Pages: 1086-1098
Published online on: 03 January 2019

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Article Open Access

Lidocaine induces protective autophagy in rat C6 glioma cell line

Magdalena Izdebska, Marta Hałas-Wiśniewska, Wioletta Zielińska, Anna Klimaszewska-Wiśniewska, Dariusz Grzanka, Maciej Gagat
Pages: 1099-1111
Published online on: 14 December 2018

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Article

Histone deacetylase 7 inhibits plakoglobin expression to promote lung cancer cell growth and metastasis

Yi Sang, Longhua Sun, Yuanzhong Wu, Wenxin Yuan, Yanyan Liu, Si-Wei Li
Pages: 1112-1122
Published online on: 09 January 2019

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Article

Sorafenib/MEK inhibitor combination inhibits tumor growth and the Wnt/β‑catenin pathway in xenograft models of hepatocellular carcinoma

Hung Huynh, Richard Ong, Kah Yong Goh, Liek Yeow Lee, Florian Puehler, Arne Scholz, Oliver Politz, Dominik Mumberg, Karl Ziegelbauer
Pages: 1123-1133
Published online on: 23 January 2019

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Correction Open Access

[Corrigendum] Pituitary sex hormones enhance the pro‑metastatic potential of human lung cancer cells by downregulating the intracellular expression of heme oxygenase‑1

Ahmed Abdelbaset‑Ismail, Daniel Pedziwiatr, Gabriela Schneider, Jacek Niklinski, Radoslaw Charkiewicz, Marcin Moniuszko, Magda Kucia, Mariusz Z. Ratajczak
Pages: 1134-1134
Published online on: 03 January 2019

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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