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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2004 Volume 13 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Plasminogen activator inhibitor type-1: Its structure, biological activity and role in tumorigenesis (Review)

Joanna Chorostowska-Wynimko, Ewa Skrzypczak-Jankun, Jerzy Jankun
Pages: 759-766
Published online on: 01 June 2004

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Article

Early effects of denervation on Ca2+-handling proteins in skeletal muscle

Pamela Donoghue, Samo Ribaric, Brendan Moran, Vita Cebasek, Ida Erzen, Kay Ohlendieck
Pages: 767-772
Published online on: 01 June 2004

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Article

Helicobacter pylori induces chronic active gastritis in p53-knockout mice

Junko Nagata, Hiroshi Kijima, Atsushi Takagi, Mamoru Ito, Kazuo Goto, Hitoshi Yamazaki, Masato Nakamura, Tetsuya Mine, Yoshito Ueyama
Pages: 773-777
Published online on: 01 June 2004

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Article

Proliferative capability of hepatocytes and expression of G1-related cell cycle molecules in the development of liver cirrhosis in rats

Fumi Funakoshi, Tsutomu Masaki, Yuko Kita, Misuzu Hitomi, Kazutaka Kurokohchi, Naohito Uchida, Seishiro Watanabe, Hitoshi Yoshiji, Shigeki Kuriyama
Pages: 779-787
Published online on: 01 June 2004

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Article

The effects of cyclooxygenase-2 inhibitors on urological cancer cells

Rikio Yoshimura, Masahide Matsuyama, Yutaka Kawahito, Yoshiaki Takemoto, Kenji Tsuchida, Katsuyuki Kuratsukuri, Yoshihiro Segawa, Toshiaki Shinnka, Hajime Sano, Tatsuya Nakatani
Pages: 789-793
Published online on: 01 June 2004

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Article

Induction of apoptosis by three types of procyanidin isolated from apple (Rosaceae Malus pumila) in human stomach cancer KATO III cells

Hiroshige Hibasami, Toshihiko Shohji, Ichirou Shibuya, Kazuko Higo, Tomomasa Kanda
Pages: 795-799
Published online on: 01 June 2004

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Article

Pneumadin in the ventral prostate of rats during postnatal development: A radioimmunological and immunocytochemical study

Bogdan Miskowiak, Renata Brelinska, Jerzy Kosowicz, Anieta Konwerska, Anieszka Ziolkowska, Anna S. Belloni, Gastone G. Nussdorfer, Ludwik K. Malendowicz
Pages: 801-803
Published online on: 01 June 2004

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Article

α-actin gene mutations and polymorphisms in Italian patients with nemaline myopathy

Claudio Graziano, Enrico Bertini, Carlo Minetti, Berardino Porfirio
Pages: 805-809
Published online on: 01 June 2004

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Article

The methylenetetrahydrofolate reductase C677T polymorphism is a major determinant of coffee-induced increase of plasma homocysteine: A randomized placebo controlled study

Elisabeth Strandhagen, Henrik Zetterberg, Nibia Aires, Mona Palmér, Lars Rymo, Kaj Blennow, Sverre Landaas, Dag S. Thelle
Pages: 811-815
Published online on: 01 June 2004

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Article

Rat liver lipogenesis is modulated by interleukin-15

Joaquín López-Soriano, Neus Carbó, Vanessa Almendro, Maite Figueras, Vicent Ribas, Sílvia Busquets, Francisco J. López-Soriano, Josep M. Argilés
Pages: 817-819
Published online on: 01 June 2004

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Article

Degradation of wheat allergen in Japanese soy sauce

Makio Kobayashi, Yuichiro Hashimoto, Shoichiro Taniuchi, Soichi Tanabe
Pages: 821-827
Published online on: 01 June 2004

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Article

Acute in vivo effects of leptin and leptin fragments on corticosteroid hormone secretion and entero-insular axis in the rat

Ludwik K. Malendowicz, Tatiana Gorska, Cinzia Tortorella, Magdalena Nowak, Mariola Majchrzak, Raffaella Spinazzi, Gastone G. Nussdorfer, Krzysztof W. Nowak
Pages: 829-834
Published online on: 01 June 2004

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Article

Comparative evaluation of microsatellite marker, AP-PCR and CGH studies in primary renal cell carcinoma

Christian Hoefling, Hannelore Schmidt, Matthias Meinhardt, Andrea Lohse, Helge Taubert, Susanne Fuessel, Uta Schmidt, Katja Schuster, Gustavo Baretton, Manfred P. Wirth, Axel Meye
Pages: 835-842
Published online on: 01 June 2004

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Article

An aqueous extract of Platycodi radix inhibits LPS-induced NF-κB nuclear translocation in human cultured airway epithelial cells

Jun-Hyuk Lee, Yung-Hyun Choi, Ho-Sung Kang, Byung-Tae Choi
Pages: 843-847
Published online on: 01 June 2004

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Article

Plasma osteoprotegerin as a biochemical marker for vascular dementia and Alzheimer's disease

Enzo Emanuele, Emmanouil Peros, Giuseppe A. Scioli, Angela D'Angelo, Carlo Olivieri, Lorenza Montagna, Diego Geroldi
Pages: 849-853
Published online on: 01 June 2004

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Article

Delayed interconversion of D-glucose anomers in D2O

Willy J. Malaisse, Ingrid Verbruggen, Monique Biesemans, Rudolph Willem
Pages: 855-857
Published online on: 01 June 2004

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Article

Paradoxically decreased intracellular collagenase activity in macrophages from bronchoalveolar lavage fluid in current smokers and patients with obstructive ventilatory disorder

Yusuke Hakoda, Yoshikazu Ito, Hirotsugu Ohkubo, Hidekazu Tago, Tsuyoshi Yoshida, Kazushige Minemura, Kenta Utsumi, Masahiro Aoshima, Kazuma Ohyashiki
Pages: 859-863
Published online on: 01 June 2004

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Article

Molecular mechanism of chemoresistance to cisplatin in ovarian cancer cell lines

Toshihiro Murata, Minoru Haisa, Hirokazu Uetsuka, Tetuji Nobuhisa, Takaomi Ookawa, Yoko Tabuchi, Yasuaki Shirakawa, Tomoki Yamatsuji, Junji Matsuoka, Masahiko Nishiyama, Noriaki Tanaka, Yoshio Naomoto
Pages: 865-868
Published online on: 01 June 2004

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Article

Effects of arginine vasopressin (AVP) on the pituitary-thyroid axis in the rat: Evidence that endogenous AVP, acting via V1 receptors, lowers TSH blood concentration

Ludwik K. Malendowicz, Raffaella Spinazzi, Krzysztof W. Nowak, Gastone G. Nussdorfer, Mariola Majchrzak
Pages: 869-872
Published online on: 01 June 2004

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Article

Mitochondrial impairment induces excitotoxic death in cerebellar granule cells

Antonella Bobba, Anna Atlante, Amalia Azzariti, Giuseppe Sgaramella, Pietro Calissano, Ersilia Marra
Pages: 873-876
Published online on: 01 June 2004

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Article

IL-10 and TGF-β differ in their regulation of aminopeptidase N/CD13 expression in monocytes

A. Kehlen, M. Geisler, J. Olsen, A. Sablotzki, J. Langner, D. Riemann
Pages: 877-882
Published online on: 01 June 2004

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Article

Increased expression of antioxidant enzymes in radioresistant variant from U251 human glioblastoma cell line

Hyung-Chahn Lee, Dae-Won Kim, Kyung-Yong Jung, In-Chul Park, Myung-Jin Park, Mi-Suk Kim, Sang-Hyeok Woo, Chang-Hun Rhee, Heon Yoo, Seung-Hoon Lee, Seok-Il Hong
Pages: 883-887
Published online on: 01 June 2004

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Article

Taq1B polymorphism of CETP gene on lipid abnormalities in patients with type II diabetes mellitus

Hulya Yilmaz, Bedia Agachan, Zeynep Ermis Karaali, Turgay Isbir
Pages: 889-893
Published online on: 01 June 2004

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Article

Enhanced radiation-induced apoptosis of cancer cell lines after treatment with resveratrol

Sarah Baatout, Hanane Derradji, Paul Jacquet, Daniella Ooms, Arlette Michaux, Max Mergeay
Pages: 895-902
Published online on: 01 June 2004

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Article

Differential effects of estradiol, raloxifene and tamoxifen on estrogen receptor expression in cultured human skin fibroblasts

Jozef Haczynski, Rafal Tarkowski, Katarzyna Jarzabek, Slawomir Wolczynski, Denis A. Magoffin, Krzysztof J. Czarnocki, Maria Ziegert, Jerzy Jakowicki, Artur J. Jakimiuk
Pages: 903-908
Published online on: 01 June 2004

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Article

Superoxide anion is involved in the early apoptosis mediated by Gleditsia sinensis fruit extract

Ivy Tuang Ngo Teo, Johnny Cheuk On Tang, Chung Hin Chui, Gregory Yin Ming Cheng, Mabel Yin Chun Yau, Fung Yi Lau, Raymond Siu Ming Wong, Thomas Wai Tong Leung, Filly Cheung, Kwok Ping Ho, Chor Hing Cheng, Albert Sun Chi Chan
Pages: 909-913
Published online on: 01 June 2004

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Article

Ang II attenuates IGF-1-stimulated Na+, K+-ATPase activity via PI3K/Akt pathway in vascular smooth muscle cells

Esma R. Isenovic, Yong Meng, Nasir Jamali, Nikola Milivojevic, James R. Sowers
Pages: 915-922
Published online on: 01 June 2004

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Article

Identification and characterization of human PDZRN4L gene and mouse Pdzrn4l gene in silico

Masuko Katoh, Masaru Katoh
Pages: 923-927
Published online on: 01 June 2004

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Article

Identification and characterization of human FHDC1, mouse Fhdc1 and zebrafish fhdc1 genes in silico

Masuko Katoh, Masaru Katoh
Pages: 929-934
Published online on: 01 June 2004

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Review Open Access

Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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