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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2018 Volume 42 Issue 2

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Personalized regulation of glioblastoma cancer stem cells based on biomedical technologies: From theory to experiment (Review)

Igor Bryukhovetskiy, Arina Ponomarenko, Irina Lyakhova, Sergey Zaitsev, Yulia Zayats, Maria Korneyko, Marina Eliseikina, Polina Mischenko, Valerie Shevchenko, Hari Shanker Sharma, Aruna Sharma, Yuri Khotimchenko
Pages: 691-702
Published online on: 10 May 2018

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Article Open Access

CTLA‑4 interferes with the HBV‑specific T cell immune response (Review)

Hui Cao, Ruiwen Zhang, Wei Zhang
Pages: 703-712
Published online on: 17 May 2018

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Review Open Access

Multi‑layered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/β‑catenin signaling activation (Review)

Masaru Katoh
Pages: 713-725
Published online on: 17 May 2018

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Article Open Access

Antibacterial and antioxidant activity of different types of honey derived from Mount Olympus in Greece

Dimitrios Stagos, Nikolaos Soulitsiotis, Christina Tsadila, Stamatina Papaeconomou, Charalampos Arvanitis, Alexandros Ntontos, Fani Karkanta, Soultana Adamou‑Androulaki, Konstantinos Petrotos, Demetrios A. Spandidos, Demetrios Kouretas, Dimitris Mossialos
Pages: 726-734
Published online on: 04 May 2018

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Article Open Access

Comparative whole genome transcriptome analysis and fenugreek leaf extract modulation on cadmium‑induced toxicity in liver cells

Caroline Odewumi, Lekan M. Latinwo, Roy Leonard Lyles, Veera L.D. Badisa, Cobb‑Abdullah Ahkinyala, Marijo Kent‑First
Pages: 735-744
Published online on: 10 May 2018

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Article Open Access

Physcion 8‑O‑β‑glucopyranoside extracted from Polygonum cuspidatum exhibits anti‑proliferative and anti‑inflammatory effects on MH7A rheumatoid arthritis‑derived fibroblast‑like synoviocytes through the TGF‑β/MAPK pathway

Qin Geng, Qiaofeng Wei, Shujun Wang, Huili Qi, Qin Zhu, Xia Liu, Xiaojun Shi, Shuyun Wen
Pages: 745-754
Published online on: 30 April 2018

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Article Open Access

Breviscapine ameliorates CCl4‑induced liver injury in mice through inhibiting inflammatory apoptotic response and ROS generation

Yu Liu, Pei‑Hao Wen, Xin‑Xue Zhang, Yang Dai, Qiang He
Pages: 755-768
Published online on: 02 May 2018

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Article Open Access

Xanthatin inhibits corneal neovascularization by inhibiting the VEGFR2‑mediated STAT3/PI3K/Akt signaling pathway

Mei Shen, Xue‑Zhi Zhou, Lei Ye, Qing Yuan, Ce Shi, Pei‑Wen Zhu, Nan Jiang, Ming‑Yang Ma, Qi‑Chen Yang, Yi Shao
Pages: 769-778
Published online on: 30 April 2018

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Article Open Access

MicroRNA‑195 inhibits cell proliferation, migration and invasion by targeting defective in cullin neddylation 1 domain containing 1 in cervical cancer Retraction in /10.3892/ijmm.2021.4973

Jinyan Zhong, Hui Yuan, Xiangqian Xu, Shoufang Kong
Pages: 779-788
Published online on: 08 May 2018

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Article Open Access

Identification and antioxidant activity of synthetic peptides from phycobiliproteins of Pyropia yezoensis

Eun‑Young Kim, Youn Hee Choi, Taek‑Jeong Nam
Pages: 789-798
Published online on: 30 April 2018

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Article Open Access

High glucose suppresses the viability and proliferation of HTR‑8/SVneo cells through regulation of the miR‑137/PRKAA1/IL‑6 axis

Hai‑Yan Peng, Ming‑Qing Li, Hua‑Ping Li
Pages: 799-810
Published online on: 17 May 2018

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Article Open Access

Anti‑cancer effects of fisetin on mammary carcinoma cells via regulation of the PI3K/Akt/mTOR pathway: In vitro and in vivo studies

Xu Sun, Xueman Ma, Qiwei Li, Yong Yang, Xiaolong Xu, Jiaqi Sun, Mingwei Yu, Kexin Cao, Lin Yang, Guowang Yang, Ganlin Zhang, Xiaomin Wang
Pages: 811-820
Published online on: 02 May 2018

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Article Open Access

Expression of annexin II and stromal tenascin C promotes epithelial to mesenchymal transition and correlates with distant metastasis in pancreatic cancer

Naoko Yoneura, Shigetsugu Takano, Hideyuki Yoshitomi, Yasuyuki Nakata, Reiri Shimazaki, Shingo Kagawa, Katsunori Furukawa, Tsukasa Takayashiki, Satoshi Kuboki, Masaru Miyazaki, Masayuki Ohtsuka
Pages: 821-830
Published online on: 02 May 2018

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Article Open Access

Icariin promotes wound healing by enhancing the migration and proliferation of keratinocytes via the AKT and ERK signaling pathway

Bobin Mi, Jing Liu, Guohui Liu, Wu Zhou, Yi Liu, Liangcong Hu, Liming Xiong, Shunan Ye, Yongchao Wu
Pages: 831-838
Published online on: 14 May 2018

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Article Open Access

miR‑133b regulates proliferation and apoptosis in high‑glucose‑induced human retinal endothelial cells by targeting ras homolog family member A

Jun Yao, Jihong Wang, Yong Yao, Kelei Wang, Qianqian Zhou, Ying Tang
Pages: 839-850
Published online on: 18 May 2018

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Article Open Access

Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury Corrigendum in /10.3892/ijmm.2026.5748

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Pages: 851-860
Published online on: 09 May 2018

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Article Open Access

Upregulation of allograft inflammatory factor‑1 expression and secretion by macrophages stimulated with aldosterone promotes renal fibroblasts to a profibrotic phenotype

Yushu Li, Xingzhi Wang, Lei Zhang, Xueying Yuan, Jianbing Hao, Jie Ni, Lirong Hao
Pages: 861-872
Published online on: 10 May 2018

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Article Open Access

Overexpression of C‑sis inhibits H2O2‑induced Buffalo rat liver cell apoptosis in vitro and alleviates liver injury in a rat model of fulminant hepatic failure

Hao Ding, Zhili Wen
Pages: 873-882
Published online on: 17 May 2018

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Article Open Access

Correlation between the expression of IL‑18 and deep venous thrombosis Corrigendum in /10.3892/ijmm.2018.3843

Guangdi Li, Rudan Zhou, Xueling Zhao, Riguang Liu, Chuan Ye
Pages: 883-896
Published online on: 16 May 2018

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Article Open Access

Role of TGF‑β1 expressed in bone marrow‑derived mesenchymal stem cells in promoting bone formation in a rabbit femoral defect model

Bing‑Yin Sun, Bao‑Xiang Zhao, Jie‑Ying Zhu, Zheng‑Ping Sun, Yong‑An Shi, Feng Huang
Pages: 897-904
Published online on: 17 May 2018

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Article Open Access

GSK3β‑mediated Ser156 phosphorylation modulates a BH3‑like domain in BCL2L12 during TMZ‑induced apoptosis and autophagy in glioma cells

Cheng‑Wei Chu, Ming‑Chang Yang, Chia‑Hua Chou, Wen‑Sheng Huang, Bo‑Xiu Hsiao, Yeng‑Tseng Wang, Shean‑Jaw Chiou, Joon‑Khim Loh, Yi‑Ren Hong
Pages: 905-918
Published online on: 11 May 2018

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Article Open Access

Cannabinoid WIN-55,212-2 mesylate inhibits tumor necrosis factor-α-induced expression of nitric oxide synthase in dorsal root ganglion neurons

Rong Tan, Lijun Cao
Pages: 919-925
Published online on: 17 May 2018

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Article Open Access

Knockdown of TNF‑α alleviates acute lung injury in rats with intestinal ischemia and reperfusion injury by upregulating IL‑10 expression

Zhen Yang, Xue‑Rong Zhang, Qiong Zhao, Sheng‑Lan Wang, Liu‑Lin Xiong, Piao Zhang, Bing Yuan, Zi‑Bing Zhang, Shu‑Yuan Fan, Ting‑Hua Wang, Yun‑Hui Zhang
Pages: 926-934
Published online on: 14 May 2018

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Article Open Access

Role of TXNDC5 in tumorigenesis of colorectal cancer cells: In vivo and in vitro evidence

Fengbo Tan, Hong Zhu, Xiao He, Nanhui Yu, Xingwen Zhang, Haifan Xu, Haiping Pei
Pages: 935-945
Published online on: 09 May 2018

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Article Open Access

Enhanced proliferation and differentiation of HO-1 gene-modified bone marrow-derived mesenchymal stem cells in the acute injured kidney

Nanmei Liu, Huiling Wang, Guofeng Han, Jin Cheng, Weifeng Hu, Jinyuan Zhang
Pages: 946-956
Published online on: 11 May 2018

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Article Open Access

Regulation of interferon signaling and HCV‑RNA replication by extracellular matrix

Takuya Kuwashiro, Shinji Iwane, Xia Jinghe, Sachiko Matsuhashi, Yuichiro Eguchi, Keizo Anzai, Kazuma Fujimoto, Toshihiko Mizuta, Naoya Sakamoto, Masanori Ikeda, Nobuyuki Kato, Iwata Ozaki
Pages: 957-965
Published online on: 18 May 2018

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Article Open Access

Overexpression of PRDM13 inhibits glioma cells via Rho and GTP enzyme activation protein

Linna Zhang, Huimei Cao, Tao He, Jijuan Yang, Hong Tao, Yin Wang, Qikuan Hu
Pages: 966-974
Published online on: 14 May 2018

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Article Open Access

MicroRNA‑20b‑5p promotes ventricular remodeling by targeting the TGF‑β/Smad signaling pathway in a rat model of ischemia‑reperfusion injury

Zhao‑Guang Liang, Hong Yao, Rong‑Sheng Xie, Chun‑Lin Gong, Ye Tian
Pages: 975-987
Published online on: 18 May 2018

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Article

Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation Retraction in /10.3892/ijmm.2026.5958

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li
Pages: 988-997
Published online on: 17 May 2018

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Article

miR‑494 inhibits cancer‑initiating cell phenotypes and reverses resistance to lapatinib by downregulating FGFR2 in HER2‑positive gastric cancer

Yanxia Yu, Xuejuan Yu, Hong Liu, Qingxun Song, Yongmei Yang
Pages: 998-1007
Published online on: 16 May 2018

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Article

MicroRNA‑381/Hes1 is a potential therapeutic target for spinal cord injury

Wendong Ruan, Guangzhi Ning, Shiqing Feng, Shijie Gao, Yan Hao
Pages: 1008-1017
Published online on: 08 May 2018

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Article

Cucurbitacin B inhibits tumor angiogenesis by triggering the mitochondrial signaling pathway in endothelial cells

Xian-Mei Piao, Feng Gao, Jiu-Xin Zhu, Li-Juan Wang, Xin Zhao, Xin Li, Miao-Miao Sheng, Yan Zhang
Pages: 1018-1025
Published online on: 30 April 2018

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Article

MicroRNA-137 dysregulation predisposes to osteoporotic fracture by impeding ALP activity and expression via suppression of leucine-rich repeat-containing G-protein-coupled receptor 4 expression

Xiangjun Liu, Xiaohui Xu
Pages: 1026-1033
Published online on: 17 May 2018

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Article

Inhibition of MEK/ERK/STAT3 signaling in oleuropein treatment inhibits myocardial ischemia/reperfusion

Hong‑Xu Jin, Yun‑Hu Zhang, Ruo‑Nan Guo, Su‑Nuan Zhao
Pages: 1034-1043
Published online on: 11 May 2018

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Article

Ectromelia virus upregulates the expression of heat shock protein 70 to promote viral replication

Wenyu Cheng, Huaijie Jia, Xiaoxia Wang, Xiaobing He, Qiwang Jin, Jingxin Cao, Zhizhong Jing
Pages: 1044-1053
Published online on: 04 May 2018

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Article

CTRP9 ameliorates cellular senescence via PGC‑1α/AMPK signaling in mesenchymal stem cells

Qun Li, Zhangzhang Zhu, Chengde Wang, Lin Cai, Jianglong Lu, Yongchun Wang, Jiadong Xu, Zhipeng Su, Weiming Zheng, Xianbin Chen
Pages: 1054-1063
Published online on: 09 May 2018

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Article

DNAJC3 mutation in Thai familial type 2 diabetes mellitus

Sirikul Kulanuwat, Watip Tangjittipokin, Prapaporn Jungtrakoon, Chutima Chanprasert, Jatuporn Sujjitjoon, Ninareeman Binnima, Pa‑Thai Yenchitsomanus, Nattachet Plengvidhya
Pages: 1064-1073
Published online on: 14 May 2018

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Article

Upregulated 14‑3‑3β aggravates restenosis by promoting cell migration following vascular injury in diabetic rats with elevated levels of free fatty acids

Lishuai Feng, Chaoran Dou, Jianbo Wang, Chunyu Jiang, Xu Ma, Jingjing Liu
Pages: 1074-1085
Published online on: 11 May 2018

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Article

Silencing of miR‑155 suppresses inflammatory responses in psoriasis through inflammasome NLRP3 regulation

Quan Luo, Jingxin Zeng, Wei Li, Ling Lin, Xin Zhou, Xin Tian, Weiyu Liu, Lidan Zhang, Xibao Zhang
Pages: 1086-1095
Published online on: 14 May 2018

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Article

BMP‑6 protects retinal pigment epithelial cells from oxidative stress‑induced injury by inhibiting the MAPK signaling pathways

Li Chen, Ming Liu, Yan Luan, Yingfei Liu, Zhichao Zhang, Bo Ma, Xuan Liu, Yong Liu
Pages: 1096-1105
Published online on: 14 May 2018

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Article

Luteolin induces myelodysplastic syndrome‑derived cell apoptosis via the p53‑dependent mitochondrial signaling pathway mediated by reactive oxygen species

Weimin Dong, Yan Lin, Yang Cao, Yue Liu, Xiaobao Xie, Weiying Gu
Pages: 1106-1115
Published online on: 18 May 2018

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Article

Accumulation of CD69+ tissue‑resident memory T cells in the nasal polyps of patients with chronic rhinosinusitis

Pascal Ickrath, Norbert Kleinsasser, Xin Ding, Christian Ginzkey, Niklas Beyersdorf, Rudolf Hagen, Thomas Kerkau, Stephan Hackenberg
Pages: 1116-1124
Published online on: 02 May 2018

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Article

Connexin 43 reduces susceptibility to sympathetic atrial fibrillation Corrigendum in /10.3892/ijmm.2020.4773

Beibei Luo, Yifei Yan, Zhiyu Zeng, Zhengnan Zhang, Haide Liu, Hao Liu, Jinyi Li, Weiqiang Huang, Jiangtao Wu, Yan He
Pages: 1125-1133
Published online on: 30 April 2018

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Article

Downregulation of microRNA‑34a inhibits oxidized low‑density lipoprotein‑induced apoptosis and oxidative stress in human umbilical vein endothelial cells

Xiaoming Zhong, Peng Li, Juan Li, Ruili He, Guanchang Cheng, Yanming Li
Pages: 1134-1144
Published online on: 09 May 2018

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Article

E3 ubiquitin ligase Hakai regulates cell growth and invasion, and increases the chemosensitivity to cisplatin in non‑small‑cell lung cancer cells

Zi Liu, Yuqing Wu, Zijian Tao, Liang Ma
Pages: 1145-1151
Published online on: 17 May 2018

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Article

LncRNA uc.48+ is involved in the diabetic immune and inflammatory responses mediated by P2X7 receptor in RAW264.7 macrophages

Hong Wu, Fang Wen, Mei Jiang, Qiang Liu, Yijun Nie
Pages: 1152-1160
Published online on: 09 May 2018

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Article

Apelin protects against sepsis‑induced cardiomyopathy by inhibiting the TLR4 and NLRP3 signaling pathways

Qiancheng Luo, Guorong Liu, Guo Chen, Dongfeng Guo, Lei Xu, Min Hang, Mingming Jin
Pages: 1161-1167
Published online on: 09 May 2018

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Article

Collagen peptides from soft‑shelled turtle induce calpain‑1 expression and regulate inflammatory cytokine expression in HaCaT human skin keratinocytes

Tetsushi Yamamoto, Saori Nakanishi, Kuniko Mitamura, Atsushi Taga
Pages: 1168-1180
Published online on: 08 May 2018

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Article

Efficient delivery of HBV NLS siRNAs into HepG2.2.15 cells for HBV inhibition through novel recombinant preS1‑tP proteins

Yanli Zeng, Zixi Li, Jia Shang, Yi Kang
Pages: 1181-1189
Published online on: 16 May 2018

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Article

Protective effects of dehydrocostuslactone on rat hippocampal slice injury induced by oxygen‑glucose deprivation/reoxygenation

Qipeng Zhao, Ailing Chen, Xiaobo Wang, Zhuanzhuan Zhang, Yunsheng Zhao, Yu Huang, Shuanglai Ren, Yafei Zhu
Pages: 1190-1198
Published online on: 17 May 2018

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Correction Open Access

[Corrigendum] Protective effect of angiotensin‑(1‑7) against hyperglycaemia‑induced injury in H9c2 cardiomyoblast cells via the PI3K̸Akt signaling pathway

Yi-Ying Yang, Xiu-Ting Sun, Zheng-Xun Li, Wei-Yan Chen, Xiang Wang, Mei-Ling Liang, Hui Shi, Zhi-Sheng Yang, Wu-Tao Zeng
Pages: 1199-1199
Published online on: 07 May 2018

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Journal Cover
November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Spatial multi‑omics identifies an SPP1+ macrophage‑driven anti‑apoptotic niche in osteoarthritis synovium via the SPP1‑CD44 axis

Han Gong, Hao Shen, Feng Zhang, Wei Wang, Sheng Zhou, Lei Wang, Yu Sun
Article Number: 334
Published online on: 29 September 2026

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Review Open Access

Novel insights into the role of the renal interstitial microenvironment in Randall's plaque formation (Review)

Jialiang Wang, Zhangcheng Liao, Minghui Liu, Yizhou Wang, Yu Cui, Hequn Chen, Feng Zeng, Zewu Zhu
Article Number: 333
Published online on: 29 September 2026

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Correction Open Access

[Corrigendum] Alteration of the Wnt/GSK3β/β‑catenin signalling pathway by rapamycin ameliorates pathology in an Alzheimer's disease model

Jingfei Chen, Zhimin Long, Yanzhen Li, Min  Luo, Shifang  Luo, Guiqiong He
Article Number: 332
Published online on: 28 September 2026

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Article Open Access

miR‑222‑3p inhibits diabetic skin wound healing by targeting APLN

Ruyan Jie, Ying Tang, Tingting Wu, Chenfan Zhang, Man Song, Xiaotong Zhao, Mingwei Chen
Article Number: 331
Published online on: 25 September 2026

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Correction Open Access

[Corrigendum] Adjudin delays cellular senescence through Sirt3‑mediated attenuation of ROS production

Keyi Geng, Ningzhen Fu, Xiao Yang, Weiliang Xia
Article Number: 330
Published online on: 23 September 2026

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Article Open Access

Salidroside attenuates myocardial ischemia‑reperfusion‑induced oxidative stress and ferroptosis by promoting USP11‑mediated  deubiquitination of PRDX2

Zhi-Cong Qiu, Jian-Nan Li, Yi-Zhou Li, Zi-Ming Wu, Xu-Dong Luo, Rui-Yuan Zeng, Song-Qing Lai, Shi-Tao Zhao, Li Wan
Article Number: 329
Published online on: 23 September 2026

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Reprogramming of cell death in gastric cancer: From molecular mechanisms to therapeutic potential (Review)

Mengru Liu, Zhujun Wu, Qiao Chen, Weiguo Ni, Ying Chen, Yixin Zhu, Yu Chen, Haifeng Ma, Yan Lin
Article Number: 328
Published online on: 23 September 2026

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Remimazolam attenuates myocardial ischemia/reperfusion injury by inhibiting ferroptosis involving the AKT/SLC7A11/GPX4 axis

Xiyuan Chen, Jianghong Zhao, Xingtong He, Yuqi Zhang, Jiao Wu, Chao Jiang, Yi Yang, Ji Xiao
Article Number: 327
Published online on: 22 September 2026

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Tumor‑immune spatiotemporal co‑evolution: A new paradigm for understanding and overcoming therapy resistance in metastatic castration‑resistant prostate cancer (Review)

Li Yan, Xiaoke Sun, Pengxiao Su
Article Number: 326
Published online on: 21 September 2026

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Research progress on the role of IL‑37 in gynecological and obstetrics‑related diseases (Review)

Hongjing Wang, Renukha Arjune, Weiyu Gan, Na Guo, Nan Yu, Ting Xiong
Article Number: 325
Published online on: 21 September 2026

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Expression of Concern Open Access

[Expression of Concern] PAT protein mRNA expression in primary rat hepatocytes: Effects of exposure to fatty acids

Elena Grasselli, Adriana Voci, Carlo Pesce, Laura Canesi, Emilia Fugassa, Gabriella Gallo, Laura Vergani
Article Number: 324
Published online on: 21 September 2026

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Neutrophil extracellular traps in cardiovascular disease: Mechanisms and therapeutic implications (Review)

Zhao Wang, Mingde Chang, Wenyu Shang, Yunfeng Jia, Xiaoyu Shan, Xinnong Chen, Yingxi Yang, Junping Zhang
Article Number: 323
Published online on: 18 September 2026

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Article Open Access

Sirt1 attenuates calcific aortic valve disease by inhibiting ferroptosis and enhancing mitochondrial function via the activation of the Nrf2/HO‑1/FTH1 axis

Fei Yan, Lei Shi, Yuechan Wang, Ying Zhao, Yuanyuan Wu, Dubiao Xian, Yunheng Liang, Ning Wang, Hongwang Cui, Minni Zhang
Article Number: 322
Published online on: 18 September 2026

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Article Open Access

Ketogenic diet attenuates Müller cell activation and retinal neuroinflammation in autoimmune glaucoma through acetylation‑mediated FOXO signalling

Sisi Tan, Xiaochen Wang, Yunfan Zheng, Zhenni Mou, Lihong Zeng, Jingchang Yuan, Xiao Fan, Miao Wei, Yujia Huo, Ruotong Ouyang, Yanyu Pu, Junqin Lei, Xi Gao, Dangdang Wang, Yang Peng, Hong Li
Article Number: 321
Published online on: 17 September 2026

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ILC3s as central regulators of mucosal homeostasis and disease pathogenesis (Review)

Jingwen Zhang, Lili Bao, Jiaxi Li, Xia Li, Lu Qiao, Jiaxian Cui, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Yaoqing Feng, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 320
Published online on: 17 September 2026

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Small extracellular vesicles in osteoarthritis: A double‑edged sword regulating inflammation and cartilage homeostasis (Review)

Yifan Yang, Jiachen Liang, Xiangyu Shi, Anqi Niu, Ruifang Gao, Xiuping Wu, Xiaojuan Guo, Xiaotong Shi, Kejie Cao, Bing Li, Ran Li
Article Number: 319
Published online on: 17 September 2026

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Exosomal circular RNAs in the tumor immune microenvironment: From regulatory mechanisms to therapeutic opportunities and translational hurdles (Review)

Wenlong Zhang, Nuo Chen, Liya Gong, Yu Dong, Hui Shen, Xin Liu, Jie Sun, Luxuan Liu, Zhe Jin, Liaoyuan Wang, Xue Han, Bin Zhang, Shuixing Zhang
Article Number: 318
Published online on: 17 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ginsenoside Rg1 protects against H2O2‑induced neuronal damage due to inhibition of the NLRP1 inflammasome signalling pathway in hippocampal neurons in vitro

Tan-Zhen Xu, Xiao-Yan Shen, Ling-Ling Sun, Ya-Li Chen, Bi-Qiong Zhang, Da-Ke Huang, Wei-Zu Li
Article Number: 317
Published online on: 16 September 2026

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tRNA‑derived RNAs in hepatic diseases: From biological functions to clinical translation (Review)

Yaotian Cai, Yifei Chen, Fuji Yang, Yongmin Yan, Ting Jiang
Article Number: 316
Published online on: 15 September 2026

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Monocytes in pneumonia: Functional plasticity and innate memory (Review) 

Run-Ze Li, Zhi-Han Xie, Li Chen, Yun-Xiao Shang, Fei Wang, Wan-Jie Huang, Qi Cheng
Article Number: 315
Published online on: 15 September 2026

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Correction Open Access

[Corrigendum] Integrative transcriptomic analysis unveils FXR as a key regulator of intestinal stemness and inflammation in ulcerative colitis

Hao Lin, Xinran Cheng, Yangyang Ren, Yongmei Zhang, Weixu Chen, Qingyan Lu, Yiqing Tian
Article Number: 314
Published online on: 14 September 2026

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Ferroptosis in heatstroke: Mechanisms and therapeutic perspectives (Review)

Hongguang Gao, Yang Chen, Tianshan Zhang, Yujun Shi, Rong Yao
Article Number: 313
Published online on: 10 September 2026

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Correction Open Access

[Corrigendum] Inactivation of von Hippel‑Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR‑210/VMP1 signaling pathway

Ting Liu, Le Zhao, Wei Chen, Zhen Li, Huilian Hou, Lu Ding, Xu Li
Article Number: 312
Published online on: 10 September 2026

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Interferon regulatory factors orchestrate CD8+ T cell function (Review)

Fa-Xi Wang, Chun-Liang Yang, Shan-Jie Rong, Qi-Jie Chen, Xiong-Tao Yue, Fei Sun
Article Number: 311
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Rapamycin‑induced miR‑30a downregulation inhibits senescence of VSMCs by targeting Beclin1

Pan Tan, Haiqin Wang, Junkun Zhan, Xinyu Ma, Xingjun Cui, Yanjiao Wang, Yi Wang, Jiayu Zhong, Youshuo Liu
Article Number: 310
Published online on: 07 September 2026

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Deciphering the function and mechanism of extracorporeal shock wave therapy in knee osteoarthritis (Review)

Yixuan Chen, Siqi Song, Yuchen Zhu, Shiqi Wang, Jieyuan Hu, Chenxu Liu, Yuchen Cai, Yushi Hu
Article Number: 309
Published online on: 04 September 2026

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Multi‑omics integration in osteoarthritis: Unraveling cell‑type‑specific gene‑metabolite networks for precision medicine (Review)

Ying Yang, Ruichen Zheng, Yun Zhang, Dongmei Ye, Jiale Xie, Changliang Zhu
Article Number: 308
Published online on: 03 September 2026

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Autophagy determines the fate of immune cells by regulating metabolic remodeling and PANoptosis (Review)

Yanan Guo, Xinyue Zhou, Yixiao Tian, Dan Chen, Xiaofeng Xie, Bin Zhou, Yingxia Tian, Yaqing Zhang
Article Number: 307
Published online on: 03 September 2026

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Programmed cell death in metabolic syndrome: From molecular mechanisms to therapeutic strategies (Review)

Jialin Zhong, Maofu Zhang, Yafang Zheng, Cuicui Gong, Yasheng Deng, Lisha Sun, Dongqi Zhou, Qian Zhou, Qiu Chen
Article Number: 306
Published online on: 03 September 2026

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Research progress on lysine acetylation (Review)

Minghui Zhang, Yuqi Zhang, Haoxin Yin, Junyuan Yan, Yingling Dong, Xin Zhao, Tianyi Cui, Bin Lv, Xiumei Gao
Article Number: 305
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Human ether‑à‑go‑go‑related gene mutation L539fs/47‑hERG leads to cell apoptosis through the endoplasmic reticulum stress pathway

Shuting Ma, Yun Zhao, Miaomiao Cao, Chaofeng Sun
Article Number: 304
Published online on: 02 September 2026

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Targeting integrated cell death networks in sepsis‑associated acute kidney injury: Shared regulatory nodes and diet‑related small molecule modulation (Review)

Lin Song, Aifeng He, Wei Jiang, Keran Shi, Jing Wang, Lu Xu, Jiangquan Yu, Ruiqiang Zheng
Article Number: 303
Published online on: 31 August 2026

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Article Open Access

Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease

Yuanlong Li, Hua Fan, Xiong Han, Ming Ni, Xiaodan Hou, Hailan Xia, Yinzhu Shi, Lin Zhang, Jun Sun
Article Number: 302
Published online on: 31 August 2026

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Salvianolic acid monomers against metastasis: Decoding the multilayered interception of EMT, angiogenesis and immune evasion (Review)

Shiting Jiang, Dan Liu, Tingting Wei, Qiwei Shi, Haowen Wang, Yidan Gao, Pingsu Mao, Wenli Yang
Article Number: 301
Published online on: 31 August 2026

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Retraction Open Access

[Retracted] Silencing of decoy receptor 3 (DcR3) expression by siRNA in pancreatic carcinoma cells induces Fas ligand‑mediated apoptosis in vitro and in vivo

Jian Zhou, Shiduo Song, Songbin He, Zhenxin Wang, Bing Zhang, Dechun Li, Dongming Zhu
Article Number: 300
Published online on: 31 August 2026

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Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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December-2026 Volume 58 Issue 6

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Centrosomal protein 55: Research progress on biological characteristics, disease associations and clinical translational potential (Review)

Sanmei Nong, Qiudong Huang, Kuibo Huang, Xiao Luo, Yin Huang, Wenlian Zheng, Weiyi Huang, Zhaoyun Liu
Article Number: 346
Published online on: 16 October 2026

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Multiple strategies to improve the therapeutic efficacy of mesenchymal stem cell‑derived exosome transplantation in ischemic stroke (Review)

Yan Xu, Xiaolei Zhou, Wenhui Zeng, Jiabing Wang, Lin Zhou, Lincai Li, Zhengwei Zou, Cixiang Chen, Yichi Zhang, Zhengyi He, Junsong Ye
Article Number: 345
Published online on: 14 October 2026

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Article Open Access

Resveratrol alleviates osteoarthritis progression by inhibiting NLRP3 inflammasome response via the AMPK/PPARγ signaling pathway

Shanshan Cui, Zifan Luo, Wen Qin, Bo Chen, Qiaoxia Zhang, Jianbing Ma, Jie Ma, Rui Zhang
Article Number: 344
Published online on: 14 October 2026

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Expression of Concern Open Access

[Expression of Concern] Anti‑metastatic and differential effects on protein expression of epigallocatechin‑3‑gallate in HCCLM6 hepatocellular carcinoma cells

Yunjuan Zhang, Lawrence Owusu, Wei Duan, Tao Jiang, Shizhu Zang, Ayaz Ahmed, Yi Xin
Article Number: 343
Published online on: 14 October 2026

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Six3 promoting the migration and neural differentiation of BMSCs via Btg2‑mediated Akt signaling pathway activation: A therapeutic strategy for stroke

Zhenqiang Fu, Zhixin Li, Limin Zhang, Wentao Hu, Hecheng Yang, Jingtao Wang
Article Number: 342
Published online on: 12 October 2026

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Expression of Concern Open Access

[Expression of Concern] EETs and CYP2J2 inhibit TNF‑α‑induced apoptosis in pulmonary artery endothelial cells and TGF‑β1‑induced migration in pulmonary artery smooth muscle cells

Wenjing Feng, Xizhen Xu, Gang Zhao, Geng Li, Tiantian Liu, Junjie Zhao, Ruolan Dong, Dao Wen Wang, Ling Tu
Article Number: 341
Published online on: 12 October 2026

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Gomisin A as a multi‑target therapeutic agent: Pharmacological mechanisms, pharmacokinetics and network pharmacology (Review)

Jiaqi Xu, Sha Shi, Chengkai Zhu, Qi Sui, Shanhao Zhu, Jingnan Zhang, Yi Zhang, Peng Chen
Article Number: 340
Published online on: 09 October 2026

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Multi‑target mechanisms of paeoniflorin in inflammatory regulation: A network pharmacology (Review)

Jin Zhang, Junjie Ye, Kun Jin, Xuan Sun, Xinyu Yu, Yuan Zhao, Ni Zhu
Article Number: 339
Published online on: 09 October 2026

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Mechanisms of neuroimmune crosstalk in vestibular disorders: Linking inflammation with neural circuit dysfunction (Review)

Xianfang Pan, Jin Fan, Zhiyi Yang, Zegang Yin, Zhen Li, Zhifeng Rui, Hujun Zhang, Yujie Li, Hongjuan Zhang
Article Number: 338
Published online on: 08 October 2026

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Expression of Concern Open Access

[Expression of Concern] Gambogic acid inhibits invasion of osteosarcoma via upregulation of TIMP‑1

Zeng-Feng Xin, Cheng-Chun Shen, Li-Jiang Tao, Shi-Gui Yan, Hao-Bo Wu
Article Number: 337
Published online on: 08 October 2026

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Anesthetics and cancer biology: Translational evidence from perioperative modulation to drug repurposing (Review)

Ting Yang, Jiao Tang, Muhammad Saqib Mudabbar, Huan Hu, Qiang Fu, Chunlan Pu
Article Number: 336
Published online on: 05 October 2026

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Expression of Concern Open Access

[Expression of Concern] Multiple roles of SOCS proteins: Differential expression of SOCS1 and SOCS3 in atherosclerosis

Xiao Liang, Ming He, Tao Chen, Yan Liu, Yu-Ling Tian, Yu-Liang Wu, Yan Zhao, Yan Shen, Zu-Yi Yuan
Article Number: 335
Published online on: 30 September 2026

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