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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June 2013 Volume 42 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

Significance of podoplanin expression in cancer-associated fibroblasts: A comprehensive review

Bartosz Pula, Wojciech Witkiewicz, Piotr Dziegiel, Marzena Podhorska-Okolow
Pages: 1849-1857
Published online on: 08 April 2013

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Article Open Access

The miR-221/222 cluster, miR-10b and miR-92a are highly upregulated in metastatic minimally invasive follicular thyroid carcinoma

Tomoo Jikuzono, Masashi Kawamoto, Hiroshi Yoshitake, Kunio Kikuchi, Haruki Akasu, Hitoshi Ishikawa, Mitsuyoshi Hirokawa, Akira Miyauchi, Shinichi Tsuchiya, Kazuo Shimizu, Toshihiro Takizawa
Pages: 1858-1868
Published online on: 02 April 2013

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Article Open Access

Triterpenes from Poria cocos suppress growth and invasiveness of pancreatic cancer cells through the downregulation of MMP-7 Erratum in /ijo/44/5/1781

Shujie Cheng, Isaac Eliaz, Junfang Lin, Daniel Sliva
Pages: 1869-1874
Published online on: 16 April 2013

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Article Open Access

Gain-of-function microRNA screens identify miR-193a regulating proliferation and apoptosis in epithelial ovarian cancer cells

Haruo Nakano, Yoji Yamada, Tatsuya Miyazawa, Tetsuo Yoshida
Pages: 1875-1882
Published online on: 15 April 2013

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Article Open Access

Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in human lung cancer and mesothelioma cell lines

M. Waheed Roomi, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 1883-1889
Published online on: 03 April 2013

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Article Open Access

Effects of the Smad4 C324Y mutation on thyroid cell proliferation

Sonia D'Inzeo, Arianna Nicolussi, Francesco Nardi, Anna Coppa
Pages: 1890-1896
Published online on: 17 April 2013

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Article Open Access

Antiproliferative effects of sorafenib and pegylated IFN‑α2b on human liver cancer cells in vitro and in vivo

Hironori Kusano, Sachiko Ogasawara, Jun Akiba, Masamichi Nakayama, Kosuke Ueda, Hirohisa Yano
Pages: 1897-1903
Published online on: 16 April 2013

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Article Open Access

Okadaic acid activates the PKR pathway and induces apoptosis through PKR stimulation in MG63 osteoblast-like cells

Tatsuji Haneji, Kanji Hirashima, Jumpei Teramachi, Hiroyuki Morimoto
Pages: 1904-1910
Published online on: 17 April 2013

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Article

Immunotoxin-mediated targeting of claudin-4 inhibits the proliferation of cancer cells

S. M. Hashimi, S. Yu, N. Alqurashi, D. S. Ipe, M. Q. Wei
Pages: 1911-1918
Published online on: 04 April 2013

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Article

Cigarette smoke induces nuclear translocation of heme oxygenase 1 (HO-1) in prostate cancer cells: Nuclear HO-1 promotes vascular endothelial growth factor secretion

Gabriel Birrane, Huchun Li, Suping Yang, Souvenir D. Tachado, Seyha Seng
Pages: 1919-1928
Published online on: 17 April 2013

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Article

Regulation of the expression of CLU isoforms in endometrial proliferative diseases

Paolo Fuzio, Alessio Valletti, Anna Napoli, Grazia Napoli, Gennaro Cormio, Luigi Selvaggi, Sabino Liuni, Graziano Pesole, Eugenio Maiorano, Elda Perlino
Pages: 1929-1944
Published online on: 11 April 2013

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Article

Flufenamic acid promotes angiogenesis through AMPK activation

Ruiliang Ge, Lei Hu, Yilin Tai, Feng Xue, Lei Yuan, Gongtian Wei, Yi Wang
Pages: 1945-1950
Published online on: 10 April 2013

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Article

Involvement of ribonucleotide reductase-M1 in 5-fluorouracil‑induced DNA damage in esophageal cancer cell lines

Yoshiro Aoki, Kenji Sakogawa, Jun Hihara, Manabu Emi, Yoichi Hamai, Kazuteru Kono, Lin Shi, Jiying Sun, Hiroyuki Kitao, Tsuyoshi Ikura, Hiroyuki Niida, Makoto Nakanishi, Morihito Okada, Satoshi Tashiro
Pages: 1951-1960
Published online on: 16 April 2013

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Article

Acetylation mediated by the p300/CBP-associated factor determines cellular energy metabolic pathways in cancer

Ramkumar Rajendran, Richa Garva, Hassan Ashour, Travis Leung, Ian Stratford, Marija Krstic-Demonacos, Constantinos Demonacos
Pages: 1961-1972
Published online on: 17 April 2013

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Article

DLC-1, a candidate tumor suppressor gene, inhibits the proliferation, migration and tumorigenicity of human nasopharyngeal carcinoma cells

Xiangling Feng, Cui Li, Weidong Liu, Huan Chen, Wen Zhou, Lei Wang, Bin Zhu, Kaitai Yao, Xingjun Jiang, Caiping Ren
Pages: 1973-1984
Published online on: 08 April 2013

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Article

Cytoprotective role of autophagy during paclitaxel-induced apoptosis in Saos-2 osteosarcoma cells

Hyeon Jun Kim, Seung Gee Lee, Yoon-Jae Kim, Ji-Eun Park, Kyu Yeol Lee, Young Hyun Yoo, Jong-Min Kim
Pages: 1985-1992
Published online on: 05 April 2013

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Article

Estrogen receptor β inhibits estradiol-induced proliferation and migration of MCF-7 cells through regulation of mitofusin 2 Corrigendum in /10.3892/ijo.2016.3695

Li Ma, Yueping Liu, Cuizhi Geng, Xiaowei Qi, Jun Jiang
Pages: 1993-2000
Published online on: 16 April 2013

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Article

A novel PI3K inhibitor alleviates fibrotic responses in fibroblasts derived from Peyronie's plaques

Kyung Hee Jung, Ye-Lim Ryu, Hee-Seung Lee, Hyunseung Lee, Mi Kwon Son, Hong Hua Yan, Sang-Won Hong, Ji-Kan Ryu, Sungwoo Hong, Jun‑Kyu Suh, Soon-Sun Hong
Pages: 2001-2008
Published online on: 16 April 2013

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Article

Dual specific antitumor effects of Semliki Forest virus-based DNA vector carrying suicide Escherichia coli purine nucleoside phosphorylase gene via Salmonella

Zhi-Hao Chen, Ge-Ling Huang, Ya-Qin Tu, Yu Jiang, Wu-Xing Dai
Pages: 2009-2018
Published online on: 16 April 2013

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Article

Investigation of the dose- and time-dependence of the induction of different types of cell death in a small‑cell lung cancer cell line: Implementation of the repairable-conditionally repairable model

Nikos Makris, Margareta Edgren, Panayiotis Mavroidis, Bengt K. Lind
Pages: 2019-2027
Published online on: 09 April 2013

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Article

MEK1/2 inhibition enhances the radiosensitivity of cancer cells by downregulating survival and growth signals mediated by EGFR ligands

Eun Joo Chung, Mary Ellen Urick, Naamit Kurshan, William Shield , Hiroaki Asano, Paul D. Smith, Bradley S. Scroggins, Jeffrey Burkeen, Deborah E. Citrin
Pages: 2028-2036
Published online on: 10 April 2013

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Article

Overexpression of the truncated form of Livin reveals a complex interaction with caspase-3

Gui-Hong Liu, Chun Wang, Zhen-Yu Ding
Pages: 2037-2045
Published online on: 04 April 2013

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Article

Silencing of MBD1 reverses pancreatic cancer therapy resistance through inhibition of DNA damage repair

Jin Xu, Wenwei Zhu, Wenyan Xu, Xiaobo Cui, Leon Chen, Shunrong Ji, Yi Qin, Wantong Yao, Liang Liu, Chen Liu, Jiang Long, Min Li, Xianjun Yu
Pages: 2046-2052
Published online on: 16 April 2013

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Article

Combination of FTY720 with cisplatin exhibits antagonistic effects in ovarian cancer cells: Role of autophagy

Ning Zhang, Lan Dai, Yanfei Qi, Wen Di, Pu Xia
Pages: 2053-2059
Published online on: 17 April 2013

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Article

NGX6 expression improves the sensitivity of tamoxifen-resistant MCF-7 cells through modulation of the Smad signaling pathway

Wen-Jing Zhao, Ke Wang
Pages: 2060-2068
Published online on: 08 April 2013

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Article

Kaempferol induces autophagy through AMPK and AKT signaling molecules and causes G2/M arrest via downregulation of CDK1/cyclin B in SK-HEP-1 human hepatic cancer cells

Wen-Wen Huang, Shih-Chang Tsai, Shu-Fen Peng, Meng-Wei Lin, Jo-Hua Chiang, Yu-Jen Chiu, Shinji Fushiya, Michael T. Tseng, Jai-Sing Yang
Pages: 2069-2077
Published online on: 17 April 2013

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Article

Proteomic identification of angiomotin by ProteomeLab PF-2D and correlation with clinical outcome in human clear cell renal cell carcinoma

Jin Yang, Peijun Liu, Meijuan Tian, Yuyao Li, Wei Chen, Xu Li
Pages: 2078-2086
Published online on: 10 April 2013

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Article

In vitro and in vivo growth inhibition of prostate cancer by the small molecule imiquimod

Ju-Hee Han, Junglim Lee, Soo-Jin Jeon, Eun-Sun Choi, Sung-Dae Cho, Bo-Yeon Kim, Dong-Jae Kim, Jae-Hak Park, Jong-Hwan Park
Pages: 2087-2093
Published online on: 16 April 2013

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Article

Knockdown of the Bcl-2 gene increases sensitivity to EGFR tyrosine kinase inhibitors in the H1975 lung cancer cell line harboring T790M mutation

Man Zou, Shu Xia, Liang Zhuang, Na Han, Qian Chu, Tengfei Chao, Ping Peng, Yu Chen, Qi Gui, Shiying Yu
Pages: 2094-2102
Published online on: 12 April 2013

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Article

Contribution of the PI3K/MMPs/Ln-5γ2 and EphA2/FAK/Paxillin signaling pathways to tumor growth and vasculogenic mimicry of gallbladder carcinomas

Xin-Sui Lu, Wei Sun, Chun-Yan Ge, Wen-Zhong Zhang, Yue-Zu Fan
Pages: 2103-2115
Published online on: 15 April 2013

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Article

Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples

Giovanni Luca Gravina, Andrea Mancini, Guido Ranieri, Boris Di Pasquale, Francesco Marampon, Luigi Di Clemente, Enrico Ricevuto, Claudio Festuccia
Pages: 2116-2122
Published online on: 10 April 2013

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Article

Association between chemotherapy and cognitive impairments in a large cohort of patients with colorectal cancer

Xianglin L. Du, Yi Cai, Elaine Symanski
Pages: 2123-2133
Published online on: 04 April 2013

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Article

Altered cardiac muscle mTOR regulation during the progression of cancer cachexia in the ApcMin/+ mouse

Nandini D.P.K. Manne, M. Lima, R. T. Enos, P. Wehner, J. A. Carson, Eric Blough
Pages: 2134-2140
Published online on: 11 April 2013

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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