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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2018 Volume 39 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

IMP3 overexpression occurs in various important cancer types and is linked to aggressive tumor features: A tissue microarray study on 8,877 human cancers and normal tissues

Christoph Burdelski, Nilofar Jakani-Karimi, Frank Jacobsen, Christina Möller-Koop, Sarah Minner, Ronald Simon, Guido Sauter, Stefan Steurer, Till S. Clauditz, Waldemar Wilczak
Pages: 3-12
Published online on: 02 November 2017

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Article Open Access

FSTL1 suppresses tumor cell proliferation, invasion and survival in non-small cell lung cancer

Xiaolei Ni, Xiaoming Cao, Yongquan Wu, Jian Wu
Pages: 13-20
Published online on: 31 October 2017

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Article Open Access

CCL2/CCR2 axis induces hepatocellular carcinoma invasion and epithelial-mesenchymal transition in vitro through activation of the Hedgehog pathway

Huijie Zhuang, Gang Cao, Changhua Kou, Tao Liu
Pages: 21-30
Published online on: 02 November 2017

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Article Open Access

Influence of the Twist gene on the invasion and metastasis of colon cancer

Duowei Wang, Bikash Rai, Feng Qi, Tong Liu, Jinmiao Wang, Xiaodong Wang, Bozhao Ma
Pages: 31-44
Published online on: 06 November 2017

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Article Open Access

PLCD3, a flotillin2-interacting protein, is involved in proliferation, migration and invasion of nasopharyngeal carcinoma cells

Weidong Liu, Xuxu Liu, Lei Wang, Bin Zhu, Chang Zhang, Wei Jia, Hecheng Zhu, Xingdong Liu, Meizuo Zhong, Dan Xie, Yanyu Liu, Shasha Li, Jia Shi, Jianxing Lin, Xiaomeng Xia, Xingjun Jiang, Caiping Ren
Pages: 45-52
Published online on: 06 November 2017

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Article Open Access

Placenta-specific protein 1 promotes cell proliferation and invasion in non-small cell lung cancer

Li Yang, Tian-Qi Zha, Xiang He, Liang Chen, Quan Zhu, Wei-Bing Wu, Feng-Qi Nie, Qian Wang, Chong-Shuang Zang, Mei-Ling Zhang, Jing He, Wei Li, Wen Jiang, Kai-Hua Lu
Pages: 53-60
Published online on: 09 November 2017

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Article Open Access

Crosstalk between p38 MAPK and caspase-9 regulates mitochondria-mediated apoptosis induced by tetra-α-(4-carboxyphenoxy) phthalocyanine zinc photodynamic therapy in LoVo cells

Yu Wang, Chunhui Xia, Zhiqiang Lun, Yanxin Lv, Wei Chen, Tao Li
Pages: 61-70
Published online on: 02 November 2017

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Article Open Access

miR-486 functions as a tumor suppressor in esophageal cancer by targeting CDK4/BCAS2

Baoping Lang, Song Zhao
Pages: 71-80
Published online on: 01 November 2017

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Article Open Access

Downregulation of miR‑19a‑3p promotes invasion, migration and bone metastasis via activating TGF‑β signaling in prostate cancer

Qingde Wa, Li Li, Hongcheng Lin, Xinsheng Peng, Dong Ren, Yan Huang, Peiheng He, Shuai Huang
Pages: 81-90
Published online on: 13 November 2017

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Article Open Access

Expression level of microRNA-200c is associated with cell morphology in vitro and histological differentiation through regulation of ZEB1/2 and E-cadherin in gastric carcinoma

Atsushi Kurata, Masatoshi Yamada, Shin-Ichiro Ohno, Shigeru Inoue, Hirotsugu Hashimoto, Koji Fujita, Masakatsu Takanashi, Masahiko Kuroda
Pages: 91-100
Published online on: 10 November 2017

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Article Open Access

HMGA2 facilitates epithelial-mesenchymal transition in renal cell carcinoma by regulating the TGF-β/Smad2 signaling pathway

Bo Kou, Wei Liu, Xiaoshuang Tang, Qingshan Kou
Pages: 101-108
Published online on: 10 November 2017

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Article Open Access

Significant inhibition of infantile hemangioma growth by sustained delivery of urea from liposomes-in-microspheres

Xiaoshuang Zhu, Xiaonan Guo, Dakan Liu, Yubin Gong, Jin Sun, Changxian Dong
Pages: 109-118
Published online on: 20 November 2017

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Article Open Access

EPS8 regulates proliferation, apoptosis and chemosensitivity in BCR-ABL positive cells via the BCR-ABL/PI3K/AKT/mTOR pathway

Rui Huang, Huimin Liu, Yiran Chen, Yanjie He, Qian Kang, Sanfang Tu, Yingzhi He, Xuan Zhou, Lei Wang, Jilong Yang, Anqin Wu, Yuhua Li
Pages: 119-128
Published online on: 20 November 2017

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Article Open Access

Frankincense, pine needle and geranium essential oils suppress tumor progression through the regulation of the AMPK/mTOR pathway in breast cancer

Peng Ren, Xiang Ren, Lei Cheng, Lixin Xu
Pages: 129-137
Published online on: 01 November 2017

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Article Open Access

P2Y2 receptor promotes the migration and invasion of breast cancer cells via EMT-related genes Snail and E-cadherin Corrigendum in /10.3892/or.2024.8770

Ying Qiu, Yan Liu, Wei-Hua Li, Hong-Quan Zhang, Xin-Xia Tian, Wei-Gang Fang
Pages: 138-150
Published online on: 07 November 2017

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Article Open Access

Immunogenic tumor cell death induced by chemotherapy in patients with breast cancer and esophageal squamous cell carcinoma

Keita Aoto, Kousaku Mimura, Hirokazu Okayama, Motonobu Saito, Shun Chida, Masaru Noda, Takahiro Nakajima, Katsuharu Saito, Noriko Abe, Shinji Ohki, Tohru Ohtake, Seiichi Takenoshita, Koji Kono
Pages: 151-159
Published online on: 14 November 2017

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Article Open Access

Characterization of etoposide- and cisplatin-chemoresistant retinoblastoma cell lines

Maike Busch, David Papior, Harald Stephan, Nicole Dünker
Pages: 160-172
Published online on: 16 November 2017

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Article

Downregulation of microRNA-1274a induces cell apoptosis through regulation of BMPR1B in clear cell renal cell carcinoma

Hirofumi Yoshino, Tomokazu Yonezawa, Masaya Yonemori, Kazutaka Miyamoto, Takashi Sakaguchi, Satoru Sugita, Youichi Osako, Shuichi Tatarano, Masayuki Nakagawa, Hideki Enokida
Pages: 173-181
Published online on: 15 November 2017

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Article

Effects of leptin on leptin receptor isoform expression and proliferative activity in human normal prostate and prostate cancer cell lines

Marta Szyszka, Marianna Tyczewska, Paulina Milecka, Karol Jopek, Piotr Celichowski, Ludwik K. Malendowicz, Marcin Rucinski
Pages: 182-192
Published online on: 01 November 2017

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Article

A novel mechanism of neovascularization in peritoneal dissemination via cancer-associated mesothelial cells affected by TGF-β derived from ovarian cancer

Kayo Fujikake, Hiroaki Kajiyama, Masato Yoshihara, Kimihiro Nishino, Nobuhisa Yoshikawa, Fumi Utsumi, Shiro Suzuki, Kaoru Niimi, Jun Sakata, Hiroko Mitsui, Kiyosumi Shibata, Takeshi Senga, Fumitaka Kikkawa
Pages: 193-200
Published online on: 20 November 2017

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Article

Influence of miR-7a and miR-24-3p on the SOX18 transcript in lung adenocarcinoma

Mateusz Olbromski, Adam Rzechonek, Jedrzej Grzegrzolka, Natalia Glatzel-Plucinska, Angelika Chachaj, Bozena Werynska, Marzenna Podhorska-Okolow, Piotr Dziegiel
Pages: 201-208
Published online on: 06 November 2017

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Article

Role of c-Met in the progression of human oral squamous cell carcinoma and its potential as a therapeutic target

Zujun Sun, Qi Liu, Dongxia Ye, Kaichuang Ye, Zhenhua Yang, Dong Li
Pages: 209-216
Published online on: 02 November 2017

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Article

The long non-coding RNA ENST00000547547 reduces 5-fluorouracil resistance of colorectal cancer cells via competitive binding to microRNA-31

Jian Li, Xiaorong Li, Chaoqun Cen, Xiaohui Ai, Changwei Lin, Gui Hu
Pages: 217-226
Published online on: 07 November 2017

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Article

Cepharanthine exhibits a potent anticancer activity in p53-mutated colorectal cancer cells through upregulation of p21Waf1/Cip1

Arkornnut Rattanawong, Vilawan Payon, Wacharee Limpanasittikul, Chatikorn Boonkrai, Apiwat Mutirangura, Piyanuch Wonganan
Pages: 227-238
Published online on: 09 November 2017

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Article

ω3-polyunsaturated fatty acids induce cell death through apoptosis and autophagy in glioblastoma cells: In vitro and in vivo

Soyeon Kim, Kaipeng Jing, Soyeon Shin, Soyeon Jeong, Seung-Hyeon Han, Heyrim Oh, Yoon-Seon Yoo, Jeongsu Han, Young-Joo Jeon, Jun-Young Heo, Gi-Ryang Kweon, Seung-Kiel Park, Jong-Il Park, Tong Wu, Kyu Lim
Pages: 239-246
Published online on: 16 November 2017

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Article

miR-16 mimics inhibit TGF-β1-induced epithelial-to-mesenchymal transition via activation of autophagy in non-small cell lung carcinoma cells

Hui Wang, Ying Zhang, Qian Wu, Yong-Bin Wang, Wei Wang
Pages: 247-254
Published online on: 09 November 2017

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Article

MicroRNA-615-5p targets insulin-like growth factor 2 and exerts tumor-suppressing functions in human esophageal squamous cell carcinoma

Bingyin Yang, Rui Xie, Shang-Nong Wu, Cheng-Cheng Gao, Xiao-Zhong Yang, Jing-Fang Zhou
Pages: 255-263
Published online on: 06 November 2017

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Article

Synergistic effects of the combination of 5-Aza‑CdR and suberoylanilide hydroxamic acid on the anticancer property of pancreatic cancer

Ting Han, Meng Zhuo, Hai Hu, Feng Jiao, Li-Wei Wang
Pages: 264-270
Published online on: 31 October 2017

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Article

Combined 18F-FDG PET/CT imaging and a gastric orthotopic xenograft model in nude mice are used to evaluate the efficacy of glycolysis-targeted therapy

Ting-An Wang, Shu-Lin Xian, Xing-Yu Guo, Xiao-Dong Zhang, Yun-Fei Lu
Pages: 271-279
Published online on: 31 October 2017

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Article

Effect of xanthohumol on Th1/Th2 balance in a breast cancer mouse model

Wenchao Zhang, Yanlong Pan, Panhong Gou, Cheng Zhou, Lianqing Ma, Qiming Liu, Yuping Du, Jinbo Yang, Qin Wang
Pages: 280-288
Published online on: 13 November 2017

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Article

Downregulation of microRNA-95-3p suppresses cell growth of osteosarcoma via CDKN1A/p21 expression

Xin Zhao, Yukai Yang, Jianting Xu, Yang Luo, Ying Xin, Yanbing Wang
Pages: 289-297
Published online on: 01 November 2017

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Article

Silencing of vacuolar ATPase c subunit ATP6V0C inhibits the invasion of prostate cancer cells through a LASS2/TMSG1-independent manner

Pengcheng Zou, Yifeng Yang, Xiaoyan Xu, Beiying Liu, Fang Mei, Jiangfeng You, Qichen Liu, Fei Pei
Pages: 298-306
Published online on: 10 November 2017

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Article

The screening and analysis of protein signatures and signaling associated with chemoresistance based on Protein Pathway Array technology in gastric cancer

Guodong Lian, Leping Li, Fei Ye, Daguang Wang, Jinglei Liu, Yulong Shi, Changqing Jing, Jian Suo, David Y. Zhang, Man Chen
Pages: 307-315
Published online on: 06 November 2017

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Article

Role of mitochondrial function in the invasiveness of human colon cancer cells

Chen-Sung Lin, Li-Tzu Liu, Liang-Hung Ou, Siao-Cian Pan, Chia-I Lin, Yau-Huei Wei
Pages: 316-330
Published online on: 09 November 2017

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Article

miR‑106b‑5p promotes cell cycle progression of malignant melanoma by targeting PTEN Retraction in /10.3892/or.2023.8669

Xu-Ε Chen, Pu Chen, Shan-Shan Chen, Ting Ma, Guang Shi, Ya Zhou, Ji Li, Liang Sheng
Pages: 331-337
Published online on: 16 November 2017

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Article

Aberrant hypermethylation of the HOXD10 gene in papillary thyroid cancer with BRAFV600E mutation

Yi-Ming Cao, Jun Gu, Yan-Shu Zhang, Wen-Jun Wei, Ning Qu, Duo Wen, Tian Liao, Rong-Liang Shi, Ling Zhang, Qing-Hai Ji, Yu Wang, Guo-Hua Sun, Yang-Xing Zhao, Yuan-Jin Wang, Jian Yu, Yong-Xue Zhu
Pages: 338-348
Published online on: 25 October 2017

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Article

NRP1-positive lung cancer cells possess tumor-initiating properties

Luis E. Jimenez-Hernandez, Karla Vazquez-Santillan, Rosario Castro-Oropeza, Gustavo Martinez-Ruiz, Laura Muñoz-Galindo, Carolina Gonzalez-Torres, Carlo C. Cortes-Gonzalez, Georgina Victoria-Acosta, Jorge Melendez-Zajgla, Vilma Maldonado
Pages: 349-357
Published online on: 09 November 2017

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Article

SPLUNC1 knockout enhances LPS-induced lung injury by increasing recruitment of CD11b+Gr-1+ cells to the spleen of mice

Han Zhang, Xiaoling Li, Shan Liao, Heran Wang, Pan Chen, Guangchao Zhu, Yanwei Luo, Guiyuan Li, Yanhong Zhou
Pages: 358-366
Published online on: 01 November 2017

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Article

Combined SN-38 and gefitinib treatment promotes CD44 degradation in head and neck squamous cell carcinoma cells

Toshiyuki Nanbu, Naoki Umemura, Emika Ohkoshi, Kumi Nanbu, Hiroshi Sakagami, Jun Shimada
Pages: 367-375
Published online on: 21 November 2017

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Article

Liver kinase B1 restoration promotes exosome secretion and motility of lung cancer cells

Cheng Zhang, Xiang Xiao, Minyi Chen, Hitham Aldharee, Yanfang Chen, Weiwen Long
Pages: 376-382
Published online on: 09 November 2017

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Article

ITR‑284 modulates cell differentiation in human chronic myelogenous leukemia K562 cells

Jai-Sing Yang, Chao-Ying Lee, Hsin-Chung Cho, Chi-Cheng Lu, Sheng-Chu Kuo, Yen-Fang Wen, Fuu-Jen Tsai, Miau-Rong Lee, Shih-Chang Tsai
Pages: 383-391
Published online on: 09 November 2017

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Article

A potential role for hepcidin in obesity-driven colorectal tumourigenesis

Elisabeth Phillips, Richard D. Horniblow, Vikki Poole, Matthew Bedford, Douglas G. Ward, Amanda J. Kirkham, Jeremy Tomlinson, Tariq H. Iqbal, Chris Tselepis
Pages: 392-400
Published online on: 31 October 2017

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Article

MicroRNA-326 inhibits melanoma progression by targeting KRAS and suppressing the AKT and ERK signalling pathways Retraction in /10.3892/or.2023.8488

Kang Kang, Jing Zhang, Xiaoyun Zhang, Zhao Chen
Pages: 401-410
Published online on: 02 November 2017

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Article

Glioma stem cells and their non-stem differentiated glioma cells exhibit differences in mitochondrial structure and function

Eun-Jung Kim, Xiong Jin, Ock Ran Kim, Seok Won Ham, Sung-Hye Park, Hyunggee Kim
Pages: 411-416
Published online on: 02 November 2017

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Article

Enhanced activated T cell subsets in prostate cancer patients receiving iodine-125 low-dose-rate prostate brachytherapy

Makoto Kubo, Takefumi Satoh, Hiromichi Ishiyama, Ken-Ichi Tabata, Hideyasu Tsumura, Shoko Komori, Masatsugu Iwamura, Shiro Baba, Kazushige Hayakawa, Toshihiko Kawamura, Fumiya Obata
Pages: 417-424
Published online on: 13 November 2017

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Article

Fungal mannosylation enhances human papillomavirus 16 E7 therapeutic immunity against TC-1 tumors

Zonglin Wang, Cuihua Wei, Yanjun Zhang, Wei Wang, Zheng Zhou, Gengfu Xiao
Pages: 425-432
Published online on: 08 November 2017

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Article

Complementary actions of melatonin on angiogenic factors, the angiopoietin/Tie2 axis and VEGF, in co‑cultures of human endothelial and breast cancer cells

Alicia González-González, Alicia González, Carolina Alonso-González, Javier Menéndez-Menéndez, Carlos Martínez-Campa, Samuel Cos
Pages: 433-441
Published online on: 02 November 2017

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Article

Hypoxia induces differential expression patterns of osteopontin and CD44 in colorectal carcinoma

Gisela Wohlleben, Konstantin Hauff, Martin Gasser, Ana Maria Waaga-Gasser, Tanja Grimmig, Michael Flentje, Bülent Polat
Pages: 442-448
Published online on: 01 November 2017

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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