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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2012 Volume 3 Issue 4

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Impact Factor: 2.3

Review

Stroke-induced microRNAs: The potential therapeutic role for stroke (Review)

Ping Wu, Xialin Zuo, Aimin Ji
Pages: 571-576
Published online on: 13 January 2012

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Review

Platelets and atherogenesis: Platelet anti-aggregation activity and endothelial protection from tomatoes (Solanum lycopersicum L.) (Review)

Iván Palomo, Eduardo Fuentes, Teresa Padró, Lina Badimon
Pages: 577-584
Published online on: 09 February 2012

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Review

Therapeutic strategies for head and neck cancer based on p53 status (Review)

Ichiro Ota, Noritomo Okamoto, Katsunari Yane, Akihisa Takahashi, Takashi Masui, Hiroshi Hosoi, Takeo Ohnishi
Pages: 585-591
Published online on: 03 February 2012

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Article Open Access

Resveratrol analogue HS-1793 induces the modulation of tumor-derived T cells

Yoo Jin Choi, Kwang Mo Yang, Sung Dae Kim, Young Hyun Yoo, Sang Wha Lee, Su Yeong Seo, Hongsuk Suh, Sung Tae Yee, Min Ho Jeong, Wol Soon Jo
Pages: 592-598
Published online on: 03 February 2012

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Article Open Access

Combination therapy of gemcitabine or oral S-1 with the anti-VEGF monoclonal antibody bevacizumab for pancreatic neuroendocrine carcinoma

Kazuhiko Kasuya, Yuichi Nagakawa, Minako Suzuki, Yoshiaki Suzuki, Bunso Kyo, Satoru Suzuki, Takaaki Matsudo, Takao Itoi, Akihiko Tsuchida, Tatsuya Aoki
Pages: 599-602
Published online on: 18 January 2012

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Article Open Access

Increased expression of the prolactin receptor is associated with malignant laryngeal tumors

Luis R. González-Lucano, José F. Muñoz-Valle, Rafael Ascencio-Cedillo, José A. Domínguez-Rosales, Gonzalo López-Rincón, Susana Del Toro-Arreola, Miriam Bueno‑Topete, Adrián Daneri-Navarro, Ciro Estrada-Chávez, Ana L. Pereira-Suárez
Pages: 603-607
Published online on: 30 January 2012

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Article Open Access

Synergistic effect of rhein in combination with ampicillin or oxacillin against methicillin-resistant Staphylococcus aureus

Dae-Ki Joung, Hee Joung, Da-Wun Yang, Dong-Yeul Kwon, Jang-Gi Choi, Seo Woo, Dong-Young Shin, Oh-Hyun Kweon, Kee-Tae Kweon, Dong-Won Shin
Pages: 608-612
Published online on: 25 January 2012

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Article

Aspirin upregulates the expression of neuregulin 1 and survivin after focal cerebral ischemia/reperfusion in rats

Fan He, Fang Qu, Fulin Song
Pages: 613-616
Published online on: 12 January 2012

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Article

In vitro effect of adenosine on the mRNA expression of Kir 2.1 and Kir 4.1 channels in rat retinal Müller cells at elevated hydrostatic pressure

Jun Yu, Chongda Chen, Jun Wang, Yu Cheng, Qirong Wu, Yisheng Zhong, Xi Shen
Pages: 617-620
Published online on: 19 January 2012

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Article

Osteopontin is overexpressed in colorectal carcinoma and is correlated with P53 by immunohistochemistry

Jing Li, Guang-Zhi Yang, Zi-Man Zhu, Zhi-Yong Zhou, Lin Li
Pages: 621-624
Published online on: 30 January 2012

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Article

Epigallocatechin-3-gallate decreases UVA-induced HPRT mutations in human skin fibroblasts accompanied by increased rates of senescence and apoptosis

Yang Xu, Jie Zhu, Bingrong Zhou, Dan Luo
Pages: 625-630
Published online on: 31 January 2012

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Article

Quantitative study of lung perfusion SPECT scanning and pulmonary function testing for early radiation-induced lung injury in patients with locally advanced non-small cell lung cancer

Wei Zhang, Jiezhong Wang, Mingdeng Tang, Jianji Pan, Penggang Bai, Duanyu Lin, Feiyu Qian, Fengjie Lin, Xueqin Yang, Shengli Zhang
Pages: 631-635
Published online on: 31 January 2012

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Article

Peritumoral lymphatic microvessel density is related to poor prognosis in lung adenocarcinoma: A retrospective study of 65 cases

Bi-Cheng Zhang, Sha Guan, Ya-Fei Zhang, Guo-Qing Yao, Bo Yang, Yong Zhao, Zhi-Guo Rao, Jian-Fei Gao
Pages: 636-640
Published online on: 03 February 2012

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Article

Female distance runners show a different response to post-workout consumption of wheat gluten hydrolysate compared to their male counterparts

Tomomi Hirao, Natsue Koikawa, Kazuhiro Aoki, Keishoku Sakuraba, Yuki Shimmura, Yoshio Suzuki, Keisuke Sawaki
Pages: 641-644
Published online on: 09 January 2012

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Article

The herbal medicine rikkunshito exhibits strong and differential adsorption properties for bile salts

Yoshio Araki, Ken-Ichi Mukaisho, Yoshihide Fujiyama, Takanori Hattori, Hiroyuki Sugihara
Pages: 645-649
Published online on: 09 February 2012

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Article

Capecitabine combined with (-)-epigallocatechin-3-gallate inhibits angiogenesis and tumor growth in nude mice with gastric cancer xenografts

Hongju Wu, Yan Xin, Chongan Xu, Yuping Xiao
Pages: 650-654
Published online on: 10 January 2012

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Article

Association between IL6 -174G/C and cancer: A meta-analysis of 105,482 individuals

Reng-Yun Liu, Xiaoxue Song, Ping Chen, Zhe Lei, Jingcheng Miao, Nengjun Yi, Kui Zhang, Boris Pasche, Hong-Tao Zhang
Pages: 655-664
Published online on: 13 January 2012

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Article

Survival and risk of relapse of acute lymphoblastic leukemia in a Mexican population is affected by dihydrofolate reductase gene polymorphisms

Yazmín Gómez-Gómez, Jorge Organista-Nava, Mónica Virginia Saavedra-Herrera, Ana Bertha Rivera-Ramírez, Marco Antonio Terán-Porcayo, Luz del Carmen Alarcón-Romero, Berenice Illades-Aguiar, Marco Antonio Leyva-Vázquez
Pages: 665-672
Published online on: 09 January 2012

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Article

Correlation of polymorphisms of the vascular endothelial growth factor gene and the risk of lung cancer in an ethnic Han group of North China

Yan Li, Jing Liang, Xiaolin Liu, Hairong Liu, Beibei Yin, Junjuan Xiao, Zhenqiang Bi
Pages: 673-676
Published online on: 13 January 2012

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Article

Global dysregulation of the chromosome 14q32 imprinted region in uterine carcinosarcoma

Eric J. Devor, Jillian N. De Mik, Shyam Ramachandran, Michael J. Goodheart, Kimberly K. Leslie
Pages: 677-682
Published online on: 25 January 2012

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Article

Transcervical intrauterine levobupivacaine infusion or paracervical block for pain control during endometrial biopsy

Nermin Köşüş, Aydın Köşüş, Ayşe Güler, Serap A. Simavlı, Nilgün Ö. Turhan
Pages: 683-688
Published online on: 30 January 2012

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Article

A polymorphism at the miR-502 binding site in the 3' untranslated region of the SET8 gene is associated with the outcome of small-cell lung cancer

Cuimin Ding, Ruijuan Li, Jingcui Peng, Shengmian Li, Zhanjun Guo
Pages: 689-692
Published online on: 03 February 2012

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Article

Korean red ginseng protects against neuronal damage induced by transient focal ischemia in rats

Ju Yeon Ban, Sung Wook Kang, Jong Seok Lee, Joo-Ho Chung, Young Gwan Ko, Han Sung Choi
Pages: 693-698
Published online on: 11 January 2012

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Case Report

Long-term survival of patients with hepatocellular carcinoma with pulmonary and adrenal metastasis: A case report

H. Y. Zhang, Q. J. Wu, C. H. Xie, G. Zhang
Pages: 699-702
Published online on: 16 January 2012

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Article

Impact of the -675 4G/5G polymorphism of the plasminogen activator inhibitor-1 gene on childhood IgA nephropathy

Su-Ryun Han, Cheon-Jong Kim, Byung-Cheol Lee
Pages: 703-706
Published online on: 30 January 2012

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Article

Beneficial effect of dietary Ephedra sinica on obesity and glucose intolerance in high-fat diet-fed mice

Moon-Koo Song, Jae-Young Um, Hyeung-Jin Jang, Byung-Cheol Lee
Pages: 707-712
Published online on: 30 January 2012

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Article

Connective tissue growth factor gene expression and decline in renal function in lupus nephritis

Chiraporn Tachaudomdach, Surasak Kantachuvesiri, Siribha Changsirikulchai, Surangkana Wimolluck, Koset Pinpradap, Chagriya Kitiyakara
Pages: 713-718
Published online on: 03 February 2012

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Article

Genetic polymorphisms in key DNA repair genes and risk of head and neck cancer in a Chinese population

Hua Yuan, Huizhang Li, Hongxia Ma, Yuming Niu, Yunong Wu, Shangyue Zhang, Zhibin Hu, Hongbing Shen, Ning Chen
Pages: 719-724
Published online on: 09 February 2012

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Article

Short-term outcomes of CyberKnife therapy for advanced high-risk tumors: A report of 160 cases

Yi-Shan Wang, Yuan-Yuan Wang, Peng Jiang, Jian-Jun Ma, Zhen Qu, Xi-Lin Wang, Jun-Ti Li, Xi-Feng Jia
Pages: 725-727
Published online on: 12 January 2012

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Article

Prognostic role of telomerase activity in gastric adenocarcinoma: A meta-analysis

Mu-Han Lü, Jia-Qi Deng, Ya-Ling Cao, Dian-Chun Fang, Yao Zhang, Shi-Ming Yang
Pages: 728-734
Published online on: 03 February 2012

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Article

Potent anti-inflammatory agent escin does not affect the healing of tibia fracture and abdominal wound in an animal model

Leiming Zhang, Hongsheng Wang, Tian Wang, Na Jiang, Pengfei Yu, Feiyan Liu, Yating Chong, Fenghua Fu
Pages: 735-739
Published online on: 31 January 2012

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Article

Association between subclinical hypothyroidism and Sasang constitution in a Korean population

Se-Young Ahn, Sung-Hwan Park, Su-Ryun Han, Young-Min Ahn, Byung-Cheol Lee
Pages: 740-744
Published online on: 30 January 2012

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Article

Correlation between MTA2 overexpression and tumour progression in esophageal squamous cell carcinoma

Y.P Liu, B.E. Shan, X.L. Wang, L. Ma
Pages: 745-749
Published online on: 07 February 2012

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Journal Cover
April-2026 Volume 31 Issue 4

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Impact Factor: 2.3

Article Open Access

DKK1/SMDT1 participate in Ang II‑induced mitochondrial injury of human smooth muscle cells in an abdominal aortic aneurysm cell model

Xiaoxia Chang, Baohong Yao, Zheng Liu, Zijie Guo, Pengyue Qiao, Xiaokun Li, Lin Wang, Aiqun Li
Article Number: 117
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] Vascular endothelial growth factor participates in modulating the C6 glioma‑induced migration of rat bone marrow‑derived mesenchymal stem cells and upregulates their vascular cell adhesion molecule‑1 expression

Zhiqiang Gao, Peng Cheng, Yixue Xue, Yunhui Liu
Article Number: 116
Published online on: 24 February 2026

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Case Report Open Access

Rhabdomyolysis in a patient with lung cancer with sintilimab‑induced overlap syndrome and hypothyroidism: A case report

Bingyi Chen, Yi Liu, Qin Zeng, Shitong Yan, Xiujuan Liu, Quanlin Zhao
Article Number: 115
Published online on: 17 February 2026

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Case Report Open Access

Secondary pulmonary lymphoma diagnosed by minimal residual disease detected in bronchoalveolar lavage fluid: A case report

Yingying Hu, Zheng Lv, Lehao Ren, Xin Zhao, Hong Liu, Yin Yuan
Article Number: 114
Published online on: 17 February 2026

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Review Open Access

Gut microbiota‑metabolism axis in digestive tumors: Emerging targets for novel therapies (Review)

Zhendong Yang, Siyu Wu, Xueying Yang, Bowen Sui
Article Number: 113
Published online on: 17 February 2026

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Retraction Open Access

[Retracted] Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis

Ying Xu, Guo-Jing Dai, Qian Liu, Zhen-Li Liu, Zhi-Qian Song, Li Li, Wei-Heng Chen, Na Lin
Article Number: 112
Published online on: 16 February 2026

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Article Open Access

Metformin triggers apoptosis via endoplasmic reticulum stress in HER2‑positive breast cancer cell lines

Eser Çakmak, Bi̇rşen Bi̇lgi̇ci̇
Article Number: 111
Published online on: 13 February 2026

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Article Open Access

Identification of a novel PLS1 heterozygous variant causing autosomal dominant non‑syndromic hearing loss

Chenxi Yang, Yao Xiong, Dongyang Wang, Juanzi Shi
Article Number: 110
Published online on: 12 February 2026

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Case Report

Familial SCA14: A case report with review

Han-Ke Huang, Chia-Ju Lee, Wen-Ling Cheng, Hui-Ju Chang, Chin-San Liu
Article Number: 109
Published online on: 12 February 2026

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Article Open Access

Efficacy of opioids in combination with gabapentin vs. opioids alone in the treatment of patients with cancer‑related pain due to bone metastases from malignant neoplasms: A meta‑analysis

Hongli Zhou, Jun Feng, Zuolei Tang
Article Number: 108
Published online on: 12 February 2026

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Article Open Access

Drug‑related problems in pediatric patients with chronic kidney disease: A single‑center prospective study

Xingxing Liu, Yue Li, Zhen Mao, Xin Wang, Shan Zhao, Qiu Han, Jia Liu, Yan Zhou, Shi Li, Bing Chen, Yongfu Hang, Wan Yan, Xiaoye Jin
Article Number: 107
Published online on: 12 February 2026

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Article Open Access

Effects of the WNT signaling pathway on inflammation and fibrosis in idiopathic pulmonary fibrosis: Clinical, radiological and molecular evaluation

İlknur Kaya, Ayşe Koçak Sezgi̇n, Meliha Koldemi̇r Gündüz, Şebnem Emine Parspur, Feride Marim, Mehmet Doğan, Ümran Toru Erbay
Article Number: 106
Published online on: 11 February 2026

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Article

IGFBP1 as a metabolic‑neurodegenerative biomarker in spinocerebellar ataxia type 3

Chungmin Chiu, Wenling Cheng, Tatsung Lin, Huiju Chang, Yujun Chang, Shihli Su, Chiaju Lee, Henhong Chang, Chinsan Liu
Article Number: 105
Published online on: 10 February 2026

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Case Report Open Access

Endodontic re‑treatment of the mandibular first molar with six root canals: A case report

Chen Wang, Mengyu Liu
Article Number: 104
Published online on: 09 February 2026

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Retraction Open Access

[Retracted] Effect of enhanced expression of COL8A1 on lymphatic metastasis of hepatocellular carcinoma in mice

Zhen-Hai Ma, Jin-Hui Ma, Li Jia, Yong-Fu Zhao
Article Number: 103
Published online on: 09 February 2026

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Article Open Access

Surgical treatment of extrahepatic intraabdominal hydatid cysts: A single‑centre retrospective analysis

Fatih Dal, Tutkun Talih, Muhammet Akyüz, Uğur Topal, Gökhan Sönmez, Erdoğan Mütevelli Sözüer, Hizir Yakup Akyildiz, Mustafa Karaağaç, Sedat Çarkit, Doğan Gürkan İslam
Article Number: 102
Published online on: 09 February 2026

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Article Open Access

Analysis of independent prognostic factors for the occurrence and severity of heart failure after chemotherapy in patients with small cell lung cancer 

Jieqiong Zhao, Xiao Wang, Xiaoxue Liu, Wei Zhao, Xia Lu, Ruijie Li, Xiang Sun
Article Number: 101
Published online on: 09 February 2026

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Case Report

Sagittal sinus thrombosis in pregnancy: A case report

Zaheera Saadia, Misbah Ilyas, Jayd Saud Althwiny, Fai Alaqel, Alanoud Abdullah Alsufayri, Lujain Husain Almutairi
Article Number: 100
Published online on: 05 February 2026

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Article

Elevated PGE2 and COX‑2 expression in villous adenoma: Implications for electrolyte depletion syndrome

Shiki Fujino, Hiroyuki Fukuda, Katsuki Danno, Takashi Takeda, Masaya Higashiguchi, Kozo Noguchi, Takefumi Hirao, Aya Ito, Norikatsu Miyoshi, Yoshio Oka
Article Number: 99
Published online on: 04 February 2026

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Article Open Access

Wogonin as a potential therapeutic agent for psoriasis: Core target identification and validation

Yu Lu, Xiaomei Zhou, Yiyu Guo, Fengrui Zhang, Jirong Wang, Jinhong Ge, Yan Xiao, Dengke Yang
Article Number: 98
Published online on: 04 February 2026

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Expression of Concern Open Access

[Expression of Concern] Glibenclamide exacerbates adriamycin‑induced cardiotoxicity by activating oxidative stress‑induced endoplasmic reticulum stress in rats

Meng-Lin Liu, Meng-Long Wang, Jing-Jun Lv, Jie Wei, Jun Wan
Article Number: 97
Published online on: 04 February 2026

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Review

Key role of the autonomic nervous system in breast cancer (Review)

Min Wu, Zhiwu Zhang, Lu Zhou, Shiqi Liu, Qing Chen, Cui Guo, Shasha Zhao, Xuedan Chen
Article Number: 96
Published online on: 04 February 2026

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Review Open Access

Senescent hepatic stellate cells drive inflammation and disease progression in MASH (Review)

Zhiqi Han, Yiran She, Di Wu, Nuo Zhang, Zheyuan Liu, Zhongyuan Wang, Xiaoying Zhou, Shuo Li
Article Number: 95
Published online on: 04 February 2026

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Article Open Access

PUM2 knockdown regulates the expression and alternative splicing of genes associated with myocardial fibrosis in H9C2 cells

Zilong Zhang, Hangyu Zhou, Diliyaer Adili, Wei Zhu, Yong Liu, Wenzheng Zhou, Zhao Wang, Jie Li
Article Number: 94
Published online on: 04 February 2026

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Case Report

A novel human papillomavirus‑induced ‘doughnut wart’ lesion treated with 5‑aminolevulinic acid photodynamic therapy: A case report

Ke Li, Yitao Qian, Wenjing Zha, Lei Shi
Article Number: 93
Published online on: 04 February 2026

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Case Report Open Access

Comprehensive diagnosis and individualized treatment of multiple primary lung cancer: A case report

Guoxiong Zeng, Yunyan Zhou, Wang Wan, Biao Deng, Chunyuan Chen, Zhu Liang
Article Number: 92
Published online on: 03 February 2026

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Review Open Access

Pathophysiological mechanisms of fatigue and multidisciplinary management strategies (Review)

Hong Zhou, Wenwen Yu, Jiaming Lei, Runzhi Chang, Yingjia Cheng, Guorui Wang, Li Lin
Article Number: 91
Published online on: 03 February 2026

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Case Report Open Access

A rare upstream regulatory region mutation in APC presenting as classical familial adenomatous polyposis: A case report and literature review

Chi-Han Yang, Yen-Cheng Chen, Tsung-Kun Chang, Wei-Chih Su, Ching-Wen Huang, Hsiang-Lin Tsai, Jaw-Yuan Wang
Article Number: 90
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] lncRNA MIAT promote cell invasion and migration in esophageal cancer

Weiguo Zhang, Qiang Chen, Caipeng Lei
Article Number: 89
Published online on: 02 February 2026

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Review Open Access

Mitochondria‑driven ferroptosis in intervertebral disc degeneration: A novel target in age‑related spinal diseases (Review)

Yang Hou, Xiaolei Yang, Duorun Qiu, Lei Liu, Jiangang Shi, Yongfei Guo
Article Number: 88
Published online on: 02 February 2026

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Case Report

Preoperative treatment with thyroid artery embolization in a patient with a giant retrosternal goiter causing severe tracheal compression: A case report

Jingxian Li, Fang Wang, Yuanshu Du, Yonghui Wang
Article Number: 87
Published online on: 02 February 2026

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Case Report Open Access

Gastric wall thickening and gastric outlet obstruction due to peritoneal metastasis in breast cancer: A case report

Bin He, Lin Ling Li, Ting Yu, Yu Tan, Ling Zhang
Article Number: 86
Published online on: 29 January 2026

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Article Open Access

Myrrh ameliorates endometriosis by enhancing ER stress‑related apoptotic cell death

Bo-Sung Kim, Minkyoung Cho, Jung Ho Han, Jung-Sook Jin, Sung-Jin Bae, Yunju Jo, Dongryeol Ryu, Yerim Joo, Seon Beom Kim, Jongkil Joo, Inhye Kim, Ki-Tae Ha
Article Number: 85
Published online on: 29 January 2026

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May-2026 Volume 31 Issue 5

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Impact Factor: 2.3

Article

Effects of spironolactone on cytotoxic damage in osteoblasts

So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Article Number: 122
Published online on: 27 February 2026

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Article Open Access

RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
Article Number: 121
Published online on: 27 February 2026

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Article Open Access

A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

Katarina Lundqvist, Hanna Tufvesson, Lars B. Dahlin, Marius Reichardt, Bodil Ohlsson
Article Number: 120
Published online on: 27 February 2026

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Case Report

A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
Article Number: 119
Published online on: 26 February 2026

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Review Open Access

Organelle homeostasis disruption: A driving force in the progression of cardiomyopathy (Review)

Yuxing Hou, Chao Li, Youyou Chen, Danfeng Zhong, Miaomiao Chai, Lijiao Mo, Senna Lin, Fangfang Huang, Qi Chen
Article Number: 118
Published online on: 26 February 2026

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