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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2003 Volume 11 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Transcriptional regulation by zinc-finger proteins Sp1 and MAZ involves interactions with the same cis-elements (Review)

Jun Song, Hideyo Ugai, Hatsumi Nakata-Tsutsui, Shotaro Kishikawa, Erika Suzuki, Takehide Murata, Kazunari K. Yokoyama
Pages: 547-553
Published online on: 01 May 2003

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Expression of vascular endothelial growth factor in external auditory canal cholesteatoma

Ramin Naim, Frank Riedel, Karl Hormann
Pages: 555-558
Published online on: 01 May 2003

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Article

Dextromethorphan alters gene expression in rat brain hippocampus and cortex

Ki-Hwan Lee, Joon-Ik Ahn, Dong-Hyun Yu, Hyun Chul Koh, Seok Hyeon Kim, Byung Hwan Yang, Young Seek Lee, Yong-Sung Lee
Pages: 559-568
Published online on: 01 May 2003

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Article

Global DNA methylation in relation to hMLH1 and hMSH2 protein immunoreactivity in sporadic human endometrial carcinomas

Roman Miturski, Krzysztof Postawski, Andrzej Semczuk, Michal Bogusiewicz, Wlodzimierz Baranowski, Jerzy A. Jakowicki, Gerard Keith
Pages: 569-574
Published online on: 01 May 2003

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Article

Evidence for a new microdeletion syndrome in 15q21

T. Liehr, H. Starke, A. Heller, A. Weise, V. Beensen, G. Senger, G. Kittner, M. Prechtel, U. Claussen, J. Seidel
Pages: 575-577
Published online on: 01 May 2003

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Article

Recombination cluster around FGFR2-WDR11-HTPAPL locus on human chromosome 10q26

Masuko Katoh, Masaru Katoh
Pages: 579-583
Published online on: 01 May 2003

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Article

Sepsis: A follow-up of cytokine production in different phases of septic patients

Gloria Adriana Martins, Maria Da Gloria Da Costa Carvalho, Cerli Rocha Gattass
Pages: 585-591
Published online on: 01 May 2003

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Article

Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis

Kazuhiko Kumagai, Keiko Hiyama, Tetsu Oyama, Hiroyuki Maeda, Nobuoki Kohno
Pages: 593-600
Published online on: 01 May 2003

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Article

Increased serum levels of macrophage inflammatory protein-3α in hepatocellular carcinoma: Relationship with clinical factors and prognostic importance during therapy

Kazuhiko Yamauchi, S. M. Fazle Akbar, Norio Horiike, Kojiro Michitaka, Morikazu Onji
Pages: 601-605
Published online on: 01 May 2003

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Article

Evaluation of telomerase in non-melanoma skin cancer

L. Boldrini, B. Loggini, S. Gisfredi, Y. Zucconi, D. Di Quirico, R. Biondi, G. Cervadoro, P. Barachini, F. Basolo, R. Pingitore, G. Fontanini
Pages: 607-611
Published online on: 01 May 2003

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Article

Effects of adrenomedullin and its fragment 22-52 on basal and ACTH-stimulated secretion of cultured rat adrenocortical cells

Agnieszka Ziolkowska, Katarzyna Budzynska, Marcin Trejter, Cinzia Tortorella, Anna S. Belloni, Ludwik K. Malendowicz
Pages: 613-615
Published online on: 01 May 2003

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Regulation of the cellular subpopulation ratios of normal human endometrial stromal cells by macrophage colony-stimulating factor

Tetsuji Tanaka, Naohiko Umesaki
Pages: 617-620
Published online on: 01 May 2003

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Allelotypes as potential prognostic markers in ovarian carcinoma treated with cisplatin-based chemotherapy

Satoru Nakayama, Kentaro Nakayama, Yuji Takebayashi, Kohkichi Hata, Ritsuto Fujiwaki, Manabu Fukumoto, Kohji Miyazaki
Pages: 621-625
Published online on: 01 May 2003

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Oncostatin M inhibits decidualization of normal human endometrial stromal cells

Tetsuji Tanaka, Naohiko Umesaki
Pages: 627-630
Published online on: 01 May 2003

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Article

Metabolic effects of X-ray irradiation on adult human articular chondrocytes

Toshiaki Takahashi, Hiroo Mizobuchi, Michio Toda, Akira Maeda, Shoji Mizuno, Yasuhiro Ogawa, Shoji Yoshida, Hiroshi Yamamoto
Pages: 631-634
Published online on: 01 May 2003

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Article

Human skin keratinocytes and fibroblasts express adrenomedullin and its receptors, and adrenomedullin enhances their growth in vitro by stimulating proliferation and inhibiting apoptosis

Giovanna Albertin, Gianni Carraro, Pier Paolo Parnigotto, Maria Teresa Conconi, Agnieszka Ziolkowska, Ludwik K. Malendowicz, Gastone G. Nussdorfer
Pages: 635-639
Published online on: 01 May 2003

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Article

Susceptibility of HVS-immortalized lymphocytic HSC-F cells to various strains and mutants of HIV/SIV

Mikako Fujita, Akiko Yoshida, Akiko Sakurai, Junko Tatsuki, Fumiko Ueno, Hirofumi Akari, Akio Adachi
Pages: 641-644
Published online on: 01 May 2003

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Article

Smad protein and TGF-β signaling in vascular smooth muscle cells

Hirofumi Ikedo, Kiyoshi Tamaki, Seiji Ueda, Seiya Kato, Makiko Fujii, Peter ten Dijke, Seiya Okuda
Pages: 645-650
Published online on: 01 May 2003

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Review

Requirement of drug development for chronic renal disease: Other strategies than blockade of the renin-angiotensin system (Review)

Toshihiro Okamoto
Pages: 651-654
Published online on: 01 May 2003

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Article

Epigenetic changes in pilocytic astrocytomas and medulloblastomas

Pilar Gonzalez-Gomez, M. Josefa Bello, Jesus Lomas, Dolores Arjona, M. Eva Alonso, Cinthia Amiñoso, Jose M. De Campos, Jesus Vaquero, Jose L. Sarasa, Cacilda Casartelli, Juan A. Rey
Pages: 655-660
Published online on: 01 May 2003

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Article

Influence of polarisation and differentiation on interaction of 43-kDa outer-membrane protein of Aeromonas caviae with human enterocyte-like Caco-2 cell line

Cláudio M. Rocha-De-Souza, Ana L. Mattos-Guaraldi, Raphael Hirata, Lilian O. Moreira, Luiz H. Monteiro-Leal, Angela C. Freitas-Almeida, Lucia Mendonça-Previato, José O. Previato, Arnaldo F.B. Andrade
Pages: 661-667
Published online on: 01 May 2003

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Article

Altered DNA repair capacity in young patients suffering from multiple cancers

Uwe S. Müller-Vogt, Judith E.E. Maurer, Gerhard G. Grabenbauer, Luitpold V.R. Distel, Heinrich Iro, Helmut Steinhart
Pages: 669-674
Published online on: 01 May 2003

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Article

Intracerebroventricular administration of NPY stimulates resistin gene expression in mice

Hideki Yuzuriha, Akio Inui, Kyoko Goto, Akihiro Asakawa, Mineko Fujimiya, Masato Kasuga
Pages: 675-676
Published online on: 01 May 2003

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Article Open Access

Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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Retraction Open Access

[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Review Open Access

Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Article Open Access

Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Review Open Access

Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Review Open Access

Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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Article Open Access

HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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Article Open Access

FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Review Open Access

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Review Open Access

Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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