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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2004 Volume 14 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

The possible correlation of Notch-1 and Notch-2 with clinical outcome and tumour clinicopathological parameters in human breast cancer

C. Parr, G. Watkins, W. G. Jiang
Pages: 779-786
Published online on: 01 November 2004

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Article

Co-expression of VEGF, c-Met and HGF/SF in secondary pleural tumors

Ramin Naim, Edina Tolnay, Klaus-Michael Mueller, Cornelius Kuhnen
Pages: 787-791
Published online on: 01 November 2004

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Article

Analysis of the PTCH1 signaling pathway in ovarian dermoids

Sonja Levanat, Roland Kappler, Bernhard Hemmerlein, Patrick Döring, Vesna Musani, Arijana Komar, Slavko Oreskovic, Bozidar Pavelic, Heidi Hahn
Pages: 793-799
Published online on: 01 November 2004

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Article

Stable long-term induction of perforin-positive CD8+ T cells in gut by oral administration of streptococcal preparation OK-432

Norifumi Mino, Yoshio Naomoto, Yasuhiro Shirakawa, Junji Matsuoka, Tetsuji Nobuhisa, Mehmet Gunduz, Kazuhiro Noma, Hitoshi Nagatsuka, Masahiko Kobayashi, Tomoki Yamatsuji, Minoru Haisa, Akira Gochi, Noriaki Tanaka
Pages: 801-806
Published online on: 01 November 2004

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Article

Hypermethylation of the p16 gene in normal oral mucosa of smokers

S. Ventorin von Zeidler, E. C. Miracca, M. A. Nagai, E. G. Birman
Pages: 807-811
Published online on: 01 November 2004

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Article

Novel mutations in TNFRSF1A in patients with typical tumor necrosis factor receptor-associated periodic syndrome and with systemic lupus erythematosus in Japanese

Takahiko Horiuchi, Hiroshi Tsukamoto, Hiroki Mitoma, Hiroshi Miyagawa, Yasuhiro Tamimoto, Seiji Yoshizawa, Mine Harada, Kenshi Hayashi, Chinami Hashimura, Motohiro Oribe, Seiichi Okamura
Pages: 813-818
Published online on: 01 November 2004

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Article

Anti-angiogenic effect of pyridoxal 5'-phosphate, pyridoxal and pyridoxamine on embryoid bodies derived from mouse embryonic stem cells

Kiminori Matsubara, Masaharu Mori, Reiko Akagi, Norihisa Kato
Pages: 819-823
Published online on: 01 November 2004

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Article

Alteration of the MDM2-p73-P14ARF pathway related to tumour progression during urinary bladder carcinogenesis

Thilo Schlott, Thomas Quentin, Monika Korabiowska, Bettina Budd, Ekkehard Kunze
Pages: 825-836
Published online on: 01 November 2004

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Article

Anti-monocyte chemoattractant protein-1 gene therapy prevents dimethylnitrosamine-induced hepatic fibrosis in rats

Satoru Tsuruta, Makoto Nakamuta, Munechika Enjoji, Kazuhiro Kotoh, Kenichi Hiasa, Kensuke Egashira, Hajime Nawata
Pages: 837-842
Published online on: 01 November 2004

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Article

Effects of neuropeptides B and W on the secretion and growth of rat adrenocortical cells

Anna Hochol, Giovanna Albertin, Gastone G. Nussdorfer, Raffaella Spinazzi, Agnieszka Ziolkowska, Marcin Rucinski, Ludwik K. Malendowicz
Pages: 843-847
Published online on: 01 November 2004

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Article

Ghrelin inhibits in vitro angiogenic activity of rat brain microvascular endothelial cells

Silvia Baiguera, Maria Terresa Conconi, Diego Guidolin, Giuseppina Mazzocchi, Ludwik K. Malendowicz, Pier Paolo Parnigotto, Raffaella Spinazzi, Gastone G. Nussdorfer
Pages: 849-854
Published online on: 01 November 2004

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Article

Glutathione S-transferase T1 deletion is a risk factor for developing end-stage renal disease in diabetic patients

Yu Yang, Min-Tsung Kao, Chia-Chu Chang, Shyi-Yu Chung, Chih-Mei Chen, Jeffrey J.P. Tsai, Jan-Gowth Chang
Pages: 855-859
Published online on: 01 November 2004

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Article

The Notch ligand, Delta-1, reduces TNF-α-induced growth suppression and apoptosis by decreasing activation of caspases in U937 cells

Mai Murata-Ohsawa, Shuji Tohda, Hanae Kogoshi, Nobuo Nara
Pages: 861-866
Published online on: 01 November 2004

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Article

Identification of differentiation-inducing activity produced by human bone marrow stromal cell line LP101

Masaki Hiramoto, Yutaka Kawakami, Ryusuke Nabeshima, Daisuke Shima, Hiroshi Handa, Shin Aizawa
Pages: 867-872
Published online on: 01 November 2004

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Article

Effects of leptin and leptin fragments on corticosterone secretion and growth of cultured rat adrenocortical cells

Ludwik K. Malendowicz, Raffaella Spinazzi, Cinzia Tortorella, Gastone G. Nussdorfer, Agnieszka Ziolkowska, Marcin Rucinski
Pages: 873-877
Published online on: 01 November 2004

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Article

In vitro and in vivo anti-allergic activity of soy sauce

Makio Kobayashi, Hiroaki Matsushita, Kazutoshi Yoshida, Ryo-Ichi Tsukiyama, Takashi Sugimura, Kenji Yamamoto
Pages: 879-884
Published online on: 01 November 2004

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Article

Quality of life improvement with soy sauce ingredients, Shoyu polysaccharides, in perennial allergic rhinitis: A double-blind placebo-controlled clinical study

Makio Kobayashi, Hiroaki Matsushita, Ikuo Shioya, Mitsuyori Nagai, Ryo-Ichi Tsukiyama, Masami Saito, Toshiro Sugita, Takashi Sugimura, Kenji Yamamoto
Pages: 885-889
Published online on: 01 November 2004

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Article

Expression of albumin in bone tissues and osteoblastic cells: Involvement of hormonal regulation

Koichi Ishida, Natsumi Sawada, Masayoshi Yamaguchi
Pages: 891-895
Published online on: 01 November 2004

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Article

Molecular and morphometric description of adipose tissue during weight changes: A quantitative tool for assessment of tissue texture

Claudio Pagano, Alessandra Calcagno, Luciano Giacomelli, Alessandro Poletti, Veronica Macchi, Roberto Vettor, Raffaele De Caro, Giovanni Federspil
Pages: 897-902
Published online on: 01 November 2004

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Article

Haplotype and linkage disequilibrium analysis of the CRMP1 and EVC genes

Theru A. Sivakumaran, Marci M. Lesperance
Pages: 903-907
Published online on: 01 November 2004

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Review

Implications of the evolution pattern of human T-cell leukemia retroviruses on their pathogenic virulence (Review)

Inbal Azran, Yana Schavinsky-Khrapunsky, Esther Priel, Mahmoud Huleihel, Mordechai Aboud
Pages: 909-915
Published online on: 01 November 2004

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Article

Characterization of polysaccharides from the flowers of Nerium indicum and their neuroprotective effects

Man-Shan Yu, Sau-Wan Lai, Kim-Fung Lin, Ji-Nian Fang, Wai-Hung Yuen, Raymond Chuen-Chung Chang
Pages: 917-924
Published online on: 01 November 2004

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Article

Growth inhibitory potential of effective microorganism fermentation extract (EM-X) on cancer cells

Chung Hin Chui, Gregory Yin Ming Cheng, Bin Ke, Fung Yi Lau, Raymond Siu Ming Wong, Stanton Hon Lung Kok, Sarwat Fatima, Filly Cheung, Chor Hing Cheng, Albert Sun Chi Chan, Johnny Cheuk On Tang
Pages: 925-929
Published online on: 01 November 2004

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Article

Targeting metastatic leiomyosarcoma by rapamycin plus gemcitabine: An intriguing clinical observation

Ofer Merimsky
Pages: 931-935
Published online on: 01 November 2004

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Article

Impaired apoptosis of lymphocytes derived from patient with decreased expression of caspase-8 results in Alps-like phenotype

Tomasz Grzela, Agnieszka Krauze, Katarzyna Grzela, Maciej Lazarczyk, Justyna Niderla, Robert Brawura-Biskupski-Samaha, Piotr Dziunycz, Lukasz Milewski, Grazyna Korczak-Kowalska, Marek Kulus
Pages: 937-942
Published online on: 01 November 2004

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Article

Identification and characterization of ARHGAP27 gene in silico

Yuriko Katoh, Masaru Katoh
Pages: 943-947
Published online on: 01 November 2004

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Article

Characterization of human FOXN4 gene in silico

Masuko Katoh, Masaru Katoh
Pages: 949-953
Published online on: 01 November 2004

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Review Open Access

Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Review Open Access

Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Article Open Access

Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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Review Open Access

A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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Retraction Open Access

[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Review Open Access

Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Article Open Access

Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Review Open Access

Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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Article Open Access

HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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Article Open Access

FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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