Journal Articles

Open Access

Telomere structure and telomerase in health and disease (Review)

Daniel E. Gomez, Romina G. Armando, Hernán G. Farina, Pablo Lorenzano Menna, Carolina S. Cerrudo, P. Daniel Ghiringhelli, Daniel F. Alonso

Pages: 1561-1569 Published online on: 29 August 2012
Open Access

Clonal dominance of CD133+ subset population as risk factor in tumor progression and disease recurrence of human cutaneous melanoma

Bhuvnesh K. Sharma, V. Manglik, Michael O'Connell, Ashani Weeraratna, Edward C. McCarron, Jennifer N. Broussard, Kyle A. Divito, Cynthia M. Simbulan-Rosenthal, Dean S. Rosenthal, John L. Zapas

Pages: 1570-1576 Published online on: 17 August 2012
Open Access

STAT3 signal transduction through interleukin-22 in oral squamous cell carcinoma

Lutfun Naher, Tamotsu Kiyoshima, Ieyoshi Kobayashi, Hiroko Wada, Kengo  Nagata, Hiroaki  Fujiwara, Yukiko F. Ookuma, Satoru Ozeki, Seiji Nakamura, Hidetaka  Sakai

Pages: 1577-1586 Published online on: 21 August 2012
Open Access

Epidermal growth factor induces bladder cancer cell proliferation through activation of the androgen receptor

Koji Izumi, Yichun Zheng, Yi Li, Jacqueline Zaengle, Hiroshi Miyamoto

Pages: 1587-1592 Published online on: 21 August 2012
Open Access

Evaluation of changes in the tumor microenvironment after sorafenib therapy by sequential histology and 18F-fluoromisonidazole hypoxia imaging in renal cell carcinoma

Masahiro Murakami, Songji Zhao, Yan Zhao, Nusrat Fatema Chowdhury, Wenwen Yu, Ken-Ichi Nishijima, Mitsuyoshi Takiguchi, Nagara Tamaki, Yuji Kuge

Pages: 1593-1600 Published online on: 10 September 2012
Open Access

Phase I/II study of immunotherapy using tumor antigen-pulsed dendritic cells in patients with hepatocellular carcinoma

Fujimasa Tada, Masanori Abe, Masashi Hirooka, Yoshiou Ikeda, Yoichi Hiasa, Yoon  Lee, Nam-Chul Jung, Woo-Bok Lee, Hyun-Soo Lee, Yong-Soo Bae, Morikazu Onji

Pages: 1601-1609 Published online on: 11 September 2012
Open Access

Therapeutic antitumor efficacy of anti-epidermal growth factor receptor antibody, cetuximab, against malignant pleural mesothelioma

Jun Kurai, Hiroki Chikumi, Kiyoshi Hashimoto, Miyako Takata, Takanori Sako, Kosuke Yamaguchi, Naoki Kinoshita, Masanari Watanabe, Hirokazu Touge, Haruhiko Makino, Tadashi Igishi, Hironobu Hamada, Seiji Yano, Eiji Shimizu

Pages: 1610-1618 Published online on: 24 August 2012
Open Access

Novel BRCA1 and BRCA2 pathogenic mutations in Slovene hereditary breast and ovarian cancer families

Srdjan Novaković, Maša Milatović, Petra Cerkovnik, Vida Stegel, Mateja Krajc, Marko Hočevar, Janez Žgajnar, Aleš Vakselj

Pages: 1619-1627 Published online on: 21 August 2012
Open Access

The novel resveratrol analogue HS-1793 induces apoptosis via the mitochondrial pathway in murine breast cancer cells

Hyoun-Ji Kim, Kwang-Mo Yang, Yoo-Soo Park, Yoo-Jin Choi, Ji-Hyeon Yun, Cheol-Hun Son, Hong-Suk Suh, Min-Ho Jeong, Wol-Soon Jo

Pages: 1628-1634 Published online on: 31 August 2012

Inhibitory effects of Yangzheng Xiaoji on angiogenesis and the role of the focal adhesion kinase pathway

Wen G. Jiang, Lin Ye, Ke Ji, Natasha Frewer, Jiafu Ji, Malcolm D. Mason

Pages: 1635-1642 Published online on: 11 September 2012

Clinical significance of LGR5 and CD44 expression in locally advanced rectal cancer after preoperative chemoradiotherapy

Susumu Saigusa, Yasuhiro Inoue, Koji Tanaka, Yuji Toiyama, Kohei Matsushita, Mikio Kawamura, Yoshinaga Okugawa, Junichiro Hiro, Keiichi Uchida, Yasuhiko Mohri, Masato Kusunoki

Pages: 1643-1652 Published online on: 22 August 2012

miR-203 inhibits the migration and invasion of esophageal squamous cell carcinoma by regulating LASP1

Nobuyoshi Takeshita, Mikito Mori, Masayuki Kano, Isamu Hoshino, Yasunori Akutsu, Naoyuki Hanari, Yasuo Yoneyama, Norimasa Ikeda, Yuka Isozaki, Tetsurou Maruyama, Naoki Akanuma, Yukimasa Miyazawa, Hisahiro Matsubara

Pages: 1653-1661 Published online on: 30 August 2012

Development of a unique mouse model for pancreatic cancer lymphatic metastasis

Jiang Long, Guopei Luo, Chen Liu, Xiaobo Cui, Kei Satoh, Zhiwen Xiao, Bo Zhang, Jin Xu, Quanxing Ni, Min Li, Xianjun Yu

Pages: 1662-1668 Published online on: 30 August 2012

Chronic treatment with ginsenoside Rg3 induces Akt-dependent senescence in human glioma cells

Seong Sin, Sung Young Kim, Sung Su Kim

Pages: 1669-1674 Published online on: 23 August 2012

Differential gene expression pattern in early gastric cancer by an integrative systematic approach

Seungyoon Nam, Jieun Lee, Sung-Ho Goh, Seung-Hyun Hong, Naaleum Song, Sang-Geun Jang, Il Ju Choi, Yeon-Su Lee

Pages: 1675-1682 Published online on: 06 September 2012

AKT serine/threonine protein kinase modulates bufalin-triggered intrinsic pathway of apoptosis in CAL 27 human oral cancer cells

Shih-Chang Tsai, Chi-Cheng Lu, Chao-Ying Lee, Yung-Chang Lin, Jing-Gung Chung, Sheng-Chu Kuo, Sakae Amagaya, Fei-Na Chen, Michael Yuanchien Chen, Shih-Feng Chan, Jai-Sing Yang

Pages: 1683-1692 Published online on: 23 August 2012

Glioblastoma cell line-derived spheres in serum‑containing medium versus serum-free medium: A comparison of cancer stem cell properties

Xin Hong, Khalil Chedid, Steven N. Kalkanis

Pages: 1693-1700 Published online on: 21 August 2012

Oncogenic features of the JMJD2A histone demethylase in breast cancer

William L. Berry, Sook Shin, Stan A. Lightfoot, Ralf Janknecht

Pages: 1701-1706 Published online on: 04 September 2012

Inhibition of hedgehog signaling depresses self-renewal of pancreatic cancer stem cells and reverses chemoresistance

Feng-Ting Huang, Yong-Xun Zhuan-Sun, Yan-Yan Zhuang, Shu-Li Wei, Jian Tang, Wen-Bo Chen, Shi-Neng Zhang

Pages: 1707-1714 Published online on: 22 August 2012

Anticancer effects of KI-10F: A novel compound affecting apoptosis, angiogenesis and cell growth in colon cancer

Sang-Won Hong, Kyung Hee Jung, Myung-Joo Choi, Da Young Kim, Hee‑Seung Lee, Hong-Mei Zheng, Guang Yong Li, Ibrahim  M. El‑Deeb, Byung Sun Park, So Ha Lee, Soon-Sun Hong

Pages: 1715-1722 Published online on: 27 August 2012

RL66 a second-generation curcumin analog has potent in vivo and in vitro anticancer activity in ER‑negative breast cancer models

Babasaheb Yadav, Sebastien Taurin, Lesley Larsen, Rhonda J. Rosengren

Pages: 1723-1732 Published online on: 11 September 2012

Upregulation and inhibition of the nuclear translocation of Oct4 during multistep gastric carcinogenesis

Fathyia Y. Al-Marzoqee, Ghalia Khoder, Haifa Al-Awadhi, Rony John, Azam Beg, Aron Vincze, Frank Branicki, Sherif M. Karam

Pages: 1733-1743 Published online on: 24 August 2012

Induction of LGR5 by H2O2 treatment is associated with cell proliferation via the JNK signaling pathway in colon cancer cells

Sung-Hee Kim, Kyung-Hee Kim, Byong-Chul Yoo, Ja-Lok Ku

Pages: 1744-1750 Published online on: 22 August 2012

Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations

Fabrizio Galimberti, Alexander M. Busch, Fadzai Chinyengetere, Tian Ma, David Sekula, Vincent A. Memoli, Konstantin H. Dragnev, Fang Liu, Kevin C. Johnson, Yongli Guo, Sarah J. Freemantle, Angeline S. Andrew, Patricia Greninger, David J. Robbins, Jeff Settleman, Cyril Benes, Ethan Dmitrovsky

Pages: 1751-1761 Published online on: 22 August 2012

Suppression of lymphangiogenesis in human lymphatic endothelial cells by simultaneously blocking VEGF-C and VEGF-D/VEGFR-3 with norcantharidin

Zhong-Yan Liu, Hai-Ou Qiu, Xiao-Jian Yuan, Yan-Yan Ni, Jian-Jun Sun, Wei Jing, Yue-Zu Fan

Pages: 1762-1772 Published online on: 23 August 2012

Notch1 activation contributes to tumor cell growth and proliferation in human hepatocellular carcinoma HepG2 and SMMC7721 cells

Juan Gao, Yongqiang Dong, Bicheng Zhang, Yimin Xiong, Weitian Xu, Yi Cheng, Meng Dai, Zhao Yu, Hualin Xu, Guorong Zheng

Pages: 1773-1781 Published online on: 24 August 2012

GSK3β signaling is involved in ultraviolet B-induced activation of autophagy in epidermal cells

Yang Yang, Haiping Wang, Siying Wang, Mei Xu, Mei Liu, Mingjun Liao, Jacqueline A. Frank, Sabal Adhikari, Kimberly A. Bower, Xianglin Shi, Cuiling Ma, Jia Luo

Pages: 1782-1788 Published online on: 05 September 2012

The anticancer effects of Saccharina japonica on 267B1/K-ras human prostate cancer cells

Mi Jeong Jo, Hyung Rak Kim, Gun Do Kim

Pages: 1789-1797 Published online on: 30 August 2012

Antitumor activity of AZ64 via G2/M arrest in non-small cell lung cancer

Yuwen Xue, Hening Ren, Wei Xiao, Zuoming Chu, J. Jack Lee, Li Mao

Pages: 1798-1808 Published online on: 04 September 2012

Adenovirus-mediated overexpression of BMP-9 inhibits human osteosarcoma cell growth and migration through downregulation of the PI3K/AKT pathway Corrigendum in /10.3892/ijo.2016.3714

Bo Li, Yuehua Yang, Shengdan Jiang, Binbin Ni, Ke Chen, Leisheng Jiang

Pages: 1809-1819 Published online on: 04 September 2012

KP-CoT-23 (CCDC83) is a novel immunogenic cancer/testis antigen in colon cancer

Myung-Ha Song, Jin-Mok Ha, Dong-Hoon Shin, Chang‑Hun  Lee, Lloyd Old, Sang-Yull Lee

Pages: 1820-1826 Published online on: 22 August 2012

Hypoxia increases CX3CR1 expression via HIF-1 and NF‑κB in androgen-independent prostate cancer cells

Li-Jie Xiao, Yuan-Yuan Chen, Ping Lin, Hai-Feng Zou, Feng Lin, Li-Nan Zhao, Dong Li, Liang Guo, Jie-Bing Tang, Xiu-Lan Zheng, Xiao-Guang Yu

Pages: 1827-1836 Published online on: 27 August 2012

Inhibition of the AKT/mTOR and erbB pathways by gefitinib, perifosine and analogs of gonadotropin-releasing hormone I and II to overcome tamoxifen resistance in breast cancer cells

Martin Block, Carsten Gründker, Stefanie Fister, Julia Kubin, Ludwig Wilkens, Michael D. Mueller, Bernhard Hemmerlein, Günter Emons, Andreas R. Günthert

Pages: 1845-1854 Published online on: 21 August 2012

Combination therapy targeting Raf-1 and MEK causes apoptosis of HCT116 colon cancer cells

Romesh R. Subramanian, Akio Yamakawa

Pages: 1855-1862 Published online on: 22 August 2012

Carboplatin treatment of antiestrogen-resistant breast cancer cells

Mathilde S. Larsen, Christina W. Yde, Ib J. Christensen, Anne E. Lykkesfeldt

Pages: 1863-1870 Published online on: 06 September 2012

Cell-free microRNAs in urine as diagnostic and prognostic biomarkers of bladder cancer

Seok Joong Yun, Pildu Jeong, Won-Tae Kim, Tae Hwan Kim, Young-Suk Lee, Phil Hyun Song, Yung-Hyun Choi, Isaac Yi Kim, Sung-Kwon Moon, Wun-Jae Kim

Pages: 1871-1878 Published online on: 06 September 2012

Betaine inhibits in vitro and in vivo angiogenesis through suppression of the NF-κB and Akt signaling pathways

Eui-Yeun Yi, Yung-Jin Kim

Pages: 1879-1885 Published online on: 31 August 2012
Open Access

[Retracted] Two initiation sites of early detection of colon cancer, revealed by localization of pERK1/2 in the nuclei or in aggregates at the perinuclear region of tumor cells

Abraham Amsterdam, Elias Shezen, Calanit Raanan, Letizia Schreiber, Yasmin Slilat, Yakov Fabrikant, Ehud Melzer, Rony Seger

Pages: 1887-1887 Published online on: 18 September 2012
Open Access

[Retracted] Use of multiple biomarkers for the localization and characterization of colon cancer stem cells by indirect immunocytochemistry

Abraham Amsterdam, Calanit Raanan, Letizia Schreiber, Ora Freyhan, Yakov Fabrikant, Ehud Melzer

Pages: 1888-1888 Published online on: 18 September 2012
Journal Cover

Cover Legend PDF

November 2012
Volume 41 Issue 5

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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