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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2016 Volume 49 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article

VEGF in nuclear medicine: Clinical application in cancer and future perspectives (Review) Corrigendum in /10.3892/ijo.2016.3636

Samanta Taurone, Filippo Galli, Alberto Signore, Enzo Agostinelli, Rudi A.J.O. Dierckx, Antonio Minni, Marcella Pucci, Marco Artico
Pages: 437-447
Published online on: 01 June 2016

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Article

Kinesin family members KIF11 and KIF23 as potential therapeutic targets in malignant pleural mesothelioma

Tatsuya Kato, Daiyoon Lee, Licun Wu, Priya Patel, Ahn Jin Young, Hironobu Wada, Hsin-Pei Hu, Hideki Ujiie, Mitsuhito Kaji, Satoshi Kano, Shinichi Matsuge, Hiromitsu Domen, Kichizo Kaga, Yoshiro Matsui, Hiromi Kanno, Yutaka Hatanaka, Kanako C. Hatanaka, Yoshihiro Matsuno, Marc de Perrot, Kazuhiro Yasufuku
Pages: 448-456
Published online on: 07 June 2016

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Article Open Access

Establishment and characterization of a highly immunogenic human renal carcinoma cell line

Clelia Prattichizzo, Margherita Gigante, Paola Pontrelli, Alessandro Stella, Maria Teresa Rocchetti, Maddalena Gigante, Eugenio Maiorano, Wolfgang Herr, Michele Battaglia, Loreto Gesualdo, Elena Ranieri
Pages: 457-470
Published online on: 27 May 2016

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Article Open Access

Clonal expansion of antitumor T cells in breast cancer correlates with response to neoadjuvant chemotherapy

Jae-Hyun Park, Miran Jang, Yunus Emre Tarhan, Toyomasa Katagiri, Mitsunori Sasa, Yasuo Miyoshi, Krishna R. Kalari, Vera J. Suman, Richard Weinshilboum, Liewei Wang, Judy C. Boughey, Matthew P. Goetz, Yusuke Nakamura
Pages: 471-478
Published online on: 27 May 2016

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Article Open Access

Regulation of Mucin 1 and multidrug resistance protein 1 by honokiol enhances the efficacy of doxorubicin-mediated growth suppression in mammary carcinoma cells

Padmamalini Thulasiraman, Andrea Butts Johnson
Pages: 479-486
Published online on: 23 May 2016

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Article Open Access

Combination treatment with flavonoid morin and telomerase inhibitor MST‑312 reduces cancer stem cell traits by targeting STAT3 and telomerase

Seyung S. Chung, Bryant Oliva, Sami Dwabe, Jaydutt V. Vadgama
Pages: 487-498
Published online on: 31 May 2016

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Article Open Access

TGF-β in jaw tumor fluids induces RANKL expression in stromal fibroblasts

Chiaki Yamada, Tomonao Aikawa, Emi Okuno, Kazuaki Miyagawa, Katsuhiko Amano, Sosuke Takahata, Masaaki Kimata, Masaya Okura, Seiji Iida, Mikihiko Kogo
Pages: 499-508
Published online on: 31 May 2016

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Article Open Access

Magnetofection based on superparamagnetic iron oxide nanoparticle-mediated low lncRNA HOTAIR expression decreases the proliferation and invasion of glioma stem cells

Kan Fang, Peifeng Liu, Suyan Dong, Yanjie Guo, Xinxin Cui, Xiaoying Zhu, Xuan Li, Lianghan Jiang, Te Liu, Yuncheng Wu
Pages: 509-518
Published online on: 08 June 2016

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Article

CREBRF is a potent tumor suppressor of glioblastoma by blocking hypoxia-induced autophagy via the CREB3/ATG5 pathway

Hao Xue, Jinsen Zhang, Xing Guo, Jian Wang, Jiangbing Li, Xiao Gao, Xiaofan Guo, Tong Li, Shugang Xu, Ping Zhang, Qinglin Liu, Gang Li
Pages: 519-528
Published online on: 09 June 2016

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Article

Dissociation of NSC606985 induces atypical ER-stress and cell death in prostate cancer cells

Liping Wang, Pengcheng Fu, Yuan Zhao, Guo Wang, Richard Yu, Xin Wang, Zehai Tang, Julianne Imperato-McGinley, Yuan-Shan Zhu
Pages: 529-538
Published online on: 02 June 2016

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Article

Receptor for activated C kinase 1 (RACK1) promotes the progression of OSCC via the AKT/mTOR pathway Corrigendum in /10.3892/ijo.2022.5301

Xuefeng Zhang, Na Liu, Danhua Ma, Ling Liu, Lu Jiang, Yu Zhou, Xin Zeng, Jing Li, Qianming Chen
Pages: 539-548
Published online on: 03 June 2016

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Article

The expression of miR-21 and miR-143 is deregulated by the HPV16 E7 oncoprotein and 17β-estradiol

Yazmín Gómez-Gómez, Jorge Organista-Nava, Rodolfo Ocadiz-Delgado, Enrique García-Villa, Marco Antonio Leyva-Vazquez, Berenice Illades-Aguiar, Paul F. Lambert, Alejandro García-Carrancá, Patricio Gariglio
Pages: 549-558
Published online on: 09 June 2016

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Article

S100A4 influences cancer stem cell-like properties of MGC803 gastric cancer cells by regulating GDF15 expression

Junfu Guo, Yue Bian, Yu Wang, Lisha Chen, Aiwen Yu, Xiuju Sun
Pages: 559-568
Published online on: 02 June 2016

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Article

Isolation and characterization of tumorspheres from a recurrent pineoblastoma patient: Feasibility of a patient-derived xenograft

Jiyong Kwak, Jin-Kyoung Shim, Dong Seok Kim, Ji-Hyun Lee, Junjeong Choi, Junseong Park, Kyoung-Jin Shin, Se-Hoon Kim, Pilnam Kim, Yong-Min Huh, Eui Hyun Kim, Jong Hee Chang, Sun Ho Kim, Seok-Gu Kang
Pages: 569-578
Published online on: 01 June 2016

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Article

4-Hydroxybutenolide impairs cell migration, and invasion of human oral cancer SCC-4 cells via the inhibition of NF-κB and MAPK signaling pathways Expression of Concern in /10.3892/ijo.2025.5795

Fu-Shun Yu, Meng-Liang Lin, Shu-Chun Hsu, Chien-Chih Yu, Yi-Ping Huang, Yueh-Hsiung Kuo, Jing-Gung Chung
Pages: 579-588
Published online on: 24 May 2016

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Article

Whole-genome DNA methylation and hydroxymethylation profiling for HBV-related hepatocellular carcinoma

Chao Ye, Ran Tao, Qingyi Cao, Danhua Zhu, Yini Wang, Jie Wang, Juan Lu, Ermei Chen, Lanjuan Li
Pages: 589-602
Published online on: 24 May 2016

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Article

Tanshinone I induces human colorectal cancer cell apoptosis: The potential roles of Aurora A-p53 and survivin-mediated signaling pathways

Mingjie Lu, Chen Wang, Jian Wang
Pages: 603-610
Published online on: 07 June 2016

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Article

Aldehyde dehydrogenase 3A1 is robustly upregulated in gastric cancer stem-like cells and associated with tumorigenesis

Di Wu, Yi-Ping Mou, Ke Chen, Jia-Qin Cai, Yu-Cheng Zhou, Yu Pan, Xiao-Wu Xu, Wei Zhou, Jia-Qi Gao, Ding-Wei Chen, Ren-Chao Zhang
Pages: 611-622
Published online on: 01 June 2016

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Article

Fuse-binding protein 1 is a target of the EZH2 inhibitor GSK343, in osteosarcoma cells

Xifeng Xiong, Jinli Zhang, Weiguo Liang, Wenjuan Cao, Shengnan Qin, Libing Dai, Dongping Ye , Zhihe Liu
Pages: 623-628
Published online on: 27 May 2016

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Article

2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside suppresses human colorectal cancer cell metastasis through inhibiting NF-κB activation

Chien-Liang Lin, Shu-Ling Hsieh, Wan Leung, Jiiang-Huei Jeng, Guan-Cheng Huang, Chining-Ting Lee, Chih-Chung Wu
Pages: 629-638
Published online on: 09 June 2016

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Article

Rifaximin, a non-absorbable antibiotic, inhibits the release of pro-angiogenic mediators in colon cancer cells through a pregnane X receptor-dependent pathway

Giuseppe Esposito, Stefano Gigli, Luisa Seguella, Nicola Nobile, Alessandra D'Alessandro, Marcella Pesce, Elena Capoccia, Luca Steardo, Carla Cirillo, Rosario Cuomo, Giovanni Sarnelli
Pages: 639-645
Published online on: 01 June 2016

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Article

Regulation of the RhoA/ROCK/AKT/β-catenin pathway by arginine-specific ADP-ribosytransferases 1 promotes migration and epithelial-mesenchymal transition in colon carcinoma

Guang-Lin Song, Cong-Cong Jin, Wei Zhao, Yi Tang, Ya-Lan Wang, Ming Li, Ming Xiao, Xian Li, Qing-Shu Li, Xiao Lin, Wen-Wen Chen, Jing Kuang
Pages: 646-656
Published online on: 27 May 2016

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Article

Oridonin enhances the anticancer activity of NVP-BEZ235 against neuroblastoma cells in vitro and in vivo through autophagy

Li-Di Zhang, Zhen Liu, Hua Liu, Dong-Mei Ran, Jia-Hui Guo, Bin Jiang, Ying-Li Wu, Feng-Hou Gao
Pages: 657-665
Published online on: 03 June 2016

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Article

Silencing FAT10 inhibits metastasis of osteosarcoma

Chengbin Ma, Zhiyu Zhang, Yan Cui, Hongmou Yuan, Feng Wang
Pages: 666-674
Published online on: 01 June 2016

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Article

Low expression of Toll-like receptors in peripheral blood mononuclear cells of pediatric patients with acute lymphoblastic leukemia

María Sánchez-Cuaxospa, Alejandra Contreras-Ramos, Erandi Pérez-Figueroa, Aurora Medina-Sansón, Elva Jiménez-Hernández, José R. Torres-Nava, Emilio Rojas-Castillo, Carmen Maldonado-Bernal
Pages: 675-681
Published online on: 07 June 2016

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Article

ADAM17-siRNA inhibits MCF-7 breast cancer through EGFR-PI3K-AKT activation

Xiangchao Meng, Baoshan Hu, Mohammad Monir Hossain, Guofu Chen, Ying Sun, Xuepeng Zhang
Pages: 682-690
Published online on: 24 May 2016

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Article

Anticancer activity and computational modeling of ternary copper (II) complexes with 3-indolecarboxylic acid and 1,10-phenanthroline

Zhen Zhang, Huiyun Wang, Qibao Wang, Maocai Yan, Huannan Wang, Caifeng Bi, Shanshan Sun, Yuhua Fan
Pages: 691-699
Published online on: 27 May 2016

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Article

Repression of Smad4 by miR‑205 moderates TGF-β-induced epithelial-mesenchymal transition in A549 cell lines Corrigendum in /10.3892/ijo.2021.5166

Yuanyuan Zeng, Jianjie Zhu, Dan Shen, Hualong Qin, Zhe Lei, Wei Li, Jian-An Huang, Zeyi Liu
Pages: 700-708
Published online on: 31 May 2016

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Article

Slug inhibition increases radiosensitivity of oral squamous cell carcinoma cells by upregulating PUMA

Fangfang Jiang, Lijie Zhou, Changbo Wei, Wei Zhao, Dongsheng Yu
Pages: 709-719
Published online on: 08 June 2016

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Article

MicroRNA-205 directly targets Krüppel-like factor 12 and is involved in invasion and apoptosis in basal-like breast carcinoma

Bing Guan, Qing Li, Li Shen, Qiu Rao, Yan Wang, Yun Zhu, Xiao-Jun Zhou, Xiao-Hong Li
Pages: 720-734
Published online on: 08 June 2016

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Article

Resveratrol inhibits hyperglycemia-driven ROS-induced invasion and migration of pancreatic cancer cells via suppression of the ERK and p38 MAPK signaling pathways

Lei Cao, Xin Chen, Xue Xiao, Qingyong Ma, Wei Li
Pages: 735-743
Published online on: 03 June 2016

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Article

Pomolic acid inhibits metastasis of HER2 overexpressing breast cancer cells through inactivation of the ERK pathway

Buyun Kim, Yu Chul Kim, Byoungduck Park
Pages: 744-752
Published online on: 07 June 2016

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Article

Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco-Ferreto, Gloria M. Calaf
Pages: 753-762
Published online on: 03 June 2016

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Article

Resistance of novel mouse strains different in MHC class I and the NKC domain to the development of experimental tumors

Anna Fišerová, Jan Richter, Katarína Čapková, Jana Bieblová, Romana Mikyšková, Milan Reiniš, Marie Indrová
Pages: 763-772
Published online on: 03 June 2016

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Article

SIRT3 participates in glucose metabolism interruption and apoptosis induced by BH3 mimetic S1 in ovarian cancer cells

Xi-Yan Xiang, Jin-Song Kang, Xiao-Chun Yang, Jing Su, Yao Wu, Xiao-Yu Yan, Ya-Nan Xue, Ye Xu, Yu-He Liu, Chun-Yan Yu, Zhi-Chao Zhang, Lian-Kun Sun
Pages: 773-784
Published online on: 01 June 2016

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Article

Pyrogallol induces the death of human pulmonary fibroblast cells through ROS increase and GSH depletion

Woo Hyun Park
Pages: 785-792
Published online on: 27 May 2016

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Article

Naltrexone at low doses upregulates a unique gene expression not seen with normal doses: Implications for its use in cancer therapy

Wai M. Liu, Katherine A. Scott, Jayne L. Dennis, Elwira Kaminska, Alan J. Levett, Angus G. Dalgleish
Pages: 793-802
Published online on: 07 June 2016

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Article

Prevalence and associated survival of high-risk HPV-related adenoid cystic carcinoma of the salivary glands

Xu Qian, Andreas M. Kaufmann, Chao Chen, Georgios Tzamalis, Veit M. Hofmann, Ulrich Keilholz, Michael Hummel, Andreas E. Albers
Pages: 803-811
Published online on: 03 June 2016

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Article

Increased regucalcin gene expression extends survival in breast cancer patients: Overexpression of regucalcin suppresses the proliferation and metastatic bone activity in MDA-MB-231 human breast cancer cells in vitro

Masayoshi Yamaguchi, Satoru Osuka, M. Neale Weitzmann, Mamoru Shoji, Tomiyasu Murata
Pages: 812-822
Published online on: 24 May 2016

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Article

Downregulation of the PHLDA1 gene in IMR-32 neuroblastoma cells increases levels of Aurora A, TRKB and affects proteins involved in apoptosis and autophagy pathways

Małgorzata Durbas, Irena Horwacik, Elżbieta Boratyn, Hanna Rokita
Pages: 823-837
Published online on: 08 June 2016

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Article

Exosome-derived microRNAs contribute to prostate cancer chemoresistance

Jing Li, Xin Yang, Hao Guan, Atsushi Mizokami, Evan T. Keller, Xiaozhen Xu, Xia Liu, Jiyong Tan, Longyuan Hu, Yi Lu, Jian Zhang
Pages: 838-846
Published online on: 03 June 2016

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Correction Open Access

[Corrigendum] Leptin stimulates ovarian cancer cell growth and inhibits apoptosis by increasing cyclin D1 and Mcl-1 expression via the activation of the MEK/ERK1/2 and PI3K/Akt signaling pathways

Chiachen Chen, Yuan-Ching Chang, Michael S. Lan, Mary Breslin
Pages: 847-847
Published online on: 06 June 2016

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Correction Open Access

[Corrigendum] Downregulation of cytokeratin 18 is associated with paclitaxel‑resistance and tumor aggressiveness in prostate cancer

Bo Yin, Mo Zhang, Yu Zeng, Youqiang Li, Chao Zhang, Yongsheng Song
Pages: 848-848
Published online on: 30 May 2016

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Journal Cover
March-2026 Volume 68 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Circ72309 modulates gemcitabine metabolism and gemcitabine sensitivity in pancreatic cancer: Serum Circ72309 levels as a potential predictor of treatment response

Naoko Sekiguchi, Hidenori Takahashi, Shogo Kobayashi, Kazuki Sasaki, Shinichiro Hasegawa, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Hirofumi Akita, Tadafumi Asaoka, Takehiro Noda, Junzo Shimizu, Koji Tanaka, Ryota Chijimatsu, Yuichiro Doki, Hidetoshi Eguchi
Article Number: 36
Published online on: 16 January 2026

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Review Open Access

Unveiling sex differences in pancreatic ductal adenocarcinoma: Current evidence and future directions (Review)

Sophie Rauschenberg, Elisabeth Orgler‑Gasche, Didem Karakas Zeybek, Ivonne Regel, J.-Matthias Löhr, Daniel Öhlund, Michael Günther, Lina Aguilera Munoz
Article Number: 35
Published online on: 15 January 2026

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Retraction Open Access

[Retracted] LTBP2 promotes the migration and invasion of gastric cancer cells and predicts poor outcome of patients with gastric cancer

Jun Wang, Wen-Jia Liang, Guang-Tao Min, Hong-Peng Wang, Wei Chen, Nan Yao
Article Number: 34
Published online on: 13 January 2026

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Article Open Access

KMO downregulation promotes hepatocellular carcinoma growth via 3‑HAA‑mediated mitochondrial mass and function imbalances

Ming Liu, Xintong Zhang, Yanfen Hu, Li Niu, Linzhi Guo, Guoqing Zhao, Fan Lu, Fengfeng Jia, Li Li, Hao Wu, Jianjun Zhu
Article Number: 33
Published online on: 13 January 2026

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Review Open Access

Regulatory networks of HIFs in tumor‑infiltrating immune cells: From molecular mechanisms to therapeutic implications (Review)

Chaoqun Li, Chenge Qin, Xingchen Li, Jinzhu Wang, Yang Li, Qin Sun
Article Number: 32
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] uPAR and cathepsin B knockdown inhibits radiation‑induced PKC integrated integrin signaling to the cytoskeleton of glioma‑initiating cells

Kiranmai Alapati, Sreelatha Gopinath, Rama Rao Malla, Venkata Ramesh Dasari, Jasti S. Rao
Article Number: 31
Published online on: 05 January 2026

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Article Open Access

PTPN18 functions as a tumor suppressor in breast cancer by negatively regulating cyclin E

Na Zhang, Tao Wang, Bin Bai, Xiaonan Zhang, Wenying Xu, Weilu Chen, Yang Yu, Bing Wang
Article Number: 30
Published online on: 30 December 2025

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Retraction Open Access

[Retracted] Suppression of the death gene BIK is a critical factor for resistance to tamoxifen in MCF‑7 breast cancer cells

Rubí Viedma-Rodriguez, Luis Arturo Baiza-Gutman, Alejandro García-Carrancá, Leticia Moreno-Fierros, Fabio Salamanca-Gómez, Diego Arenas-Aranda
Article Number: 29
Published online on: 23 December 2025

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Review Open Access

Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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