Journal Articles

Iron metabolism and its contribution to cancer (Review)

Ying Chen, Zhimin Fan, Ye Yang, Chunyan Gu

Pages: 1143-1154 Published online on: 20 February 2019

Mitochondrial calcium: Transport and modulation of cellular processes in homeostasis and cancer (Review)

Susana Romero-Garcia, Heriberto Prado-Garcia

Pages: 1155-1167 Published online on: 28 January 2019
Open Access

Diverse and cancer type‑specific roles of the p53 R248Q gain‑of‑function mutation in cancer migration and invasiveness

Maciej Boleslaw Olszewski, Magdalena Pruszko, Ewa Snaar‑Jagalska, Alicja Zylicz, Maciej Zylicz

Pages: 1168-1182 Published online on: 22 February 2019
Open Access

lncRNA PLAC2 activated by H3K27 acetylation promotes cell proliferation and invasion via the activation of Wnt/β‑catenin pathway in oral squamous cell carcinoma

Fubo Chen, Shengcai Qi, Xu Zhang, Jinjin Wu, Xi Yang, Raorao Wang

Pages: 1183-1194 Published online on: 01 February 2019
Open Access

Silencing of COPB2 inhibits the proliferation of gastric cancer cells and induces apoptosis via suppression of the RTK signaling pathway

Caixia An, Hailong Li, Xueyan Zhang, Jing Wang, Yi Qiang, Xinhua Ye, Qiang Li, Quanlin Guan, Yongning Zhou

Pages: 1195-1208 Published online on: 18 February 2019
Open Access

Comparison of tumor‑targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2

Anzhelika Vorobyeva, Alexey Sсhulga, Elena Konovalova, Rezan Güler, Bogdan Mitran, Javad Garousi, Sara Rinne, John Löfblom, Anna Orlova, Sergey Deyev, Vladimir Tolmachev

Pages: 1209-1220 Published online on: 11 February 2019
Open Access

FABP5 regulates the proliferation of clear cell renal cell carcinoma cells via the PI3K/AKT signaling pathway

Qi Lv, Gangmin Wang, Yinan Zhang, Xiao Han, Haoming Li, Wei Le, Minguang Zhang, Chunhui Ma, Peijun Wang, Qiang Ding

Pages: 1221-1232 Published online on: 22 February 2019
Open Access

Cathepsin B defines leader cells during the collective invasion of salivary adenoid cystic carcinoma

Jia‑Shun Wu, Zhu‑Feng Li, Hao‑Fan Wang, Xiang‑Hua Yu, Xin Pang, Jing‑Biao Wu, Sha‑Sha Wang, Mei Zhang, Xiao Yang, Ming‑Xin Cao, Ya‑Jie Tang, Xin‑Hua Liang, Min Zheng, Ya‑Ling Tang

Pages: 1233-1244 Published online on: 22 February 2019
Open Access

Upregulation of microRNA‑194‑5p inhibits hypopharyngeal carcinoma cell proliferation, migration and invasion by targeting SMURF1 via the mTOR signaling pathway

Shan Xu, Lian Hui, Ning Yang, Yan Wang, Ning Zhao, Xue‑Jun Jiang

Pages: 1245-1255 Published online on: 04 February 2019
Open Access

A novel mechanism for the anticancer activity of aspirin and salicylates

Asma'u I.J. Bashir, Chandra S. Kankipati, Sarah Jones, Robert M. Newman, Stephen T. Safrany, Christopher J. Perry, Iain D. Nicholl

Pages: 1256-1270 Published online on: 29 January 2019
Open Access

Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling

Chi-Cheng Lu, Jo-Hua Chiang, Fuu-Jen Tsai, Yuan-Man Hsu, Yu-Ning Juan, Jai-Sing Yang, Hong-Yi Chiu

Pages: 1271-1281 Published online on: 30 January 2019
Open Access

miR‑300 regulates tumor proliferation and metastasis by targeting lymphoid enhancer‑binding factor 1 in hepatocellular carcinoma

Yufo Chen, Yuanyuan Guo, Yawei Li, Jingwen Yang, Jing Liu, Qiong Wu, Rui Wang

Pages: 1282-1294 Published online on: 13 February 2019
Open Access

CGK062, a small chemical molecule, inhibits cancer upregulated gene 2‑induced oncogenesis through NEK2 and β‑catenin

Sirichat Kaowinn, Sangtaek Oh, Jeong Moon, Ah Young Yoo, Ho Young Kang, Mi Rim Lee, Ji Eun Kim, Dae Youn Hwang, So Eun Youn, Sang Seok Koh, Young‑Hwa Chung

Pages: 1295-1305 Published online on: 22 February 2019

Triacetyl resveratrol upregulates miRNA‑200 and suppresses the Shh pathway in pancreatic cancer: A potential therapeutic agent

Junsheng Fu, Anju Shrivastava, Sushant K. Shrivastava, Rakesh K. Srivastava, Sharmila Shankar

Pages: 1306-1316 Published online on: 28 January 2019

Long non-coding RNA TUG1 recruits miR‑29c‑3p from its target gene RGS1 to promote proliferation and metastasis of melanoma cells

Yanqian Wang, Gang Liu, Lin Ren, Kun Wang, Aimin Liu

Pages: 1317-1326 Published online on: 28 January 2019

Runx3 inhibits endothelial progenitor cell differentiation and function via suppression of HIF-1α activity

So-Yun Choo, Soo-Hyun Yoon, Dong-Jin Lee, Sun Hee Lee, Kang Li, In Hye Koo, Wooin Lee, Suk-Chul Bae, You Mie Lee

Pages: 1327-1336 Published online on: 11 February 2019

COUP‑TFII promotes epithelial‑mesenchymal transition by inhibiting miR‑34a expression in colorectal cancer

Ying Bao, Yongliang Lu, Wenming Feng, Hongbin Yu, Huihui  Guo, Yulong Tao, Qian Shi, Wei Chen, Xiang Wang

Pages: 1337-1344 Published online on: 18 February 2019

Partial agonistic effect of cetuximab on epidermal growth factor receptor and Src kinase activation in triple‑negative breast cancer cell lines

Hakan Gurdal, Matilda Merve Tuglu, Saber Yari Bostanabad, Başak Dalkiliç

Pages: 1345-1356 Published online on: 28 January 2019

MACC1 overexpression in carcinoma‑associated fibroblasts induces the invasion of lung adenocarcinoma cells via paracrine signaling

Zhuoshi Li, Tao Guo, Lei Fang, Nan Li, Xiaochao Wang, Peng Wang, Shilei Zhao, Fengzhou Li, Yanwei Cui, Xin Shu, Lei Zhao, Jinxiu Li, Chundong Gu

Pages: 1367-1375 Published online on: 30 January 2019

Protective effect of curcumin against irinotecan‑induced intestinal mucosal injury via attenuation of NF‑κB activation, oxidative stress and endoplasmic reticulum stress

Manzhao Ouyang, Zhentao Luo, Weijie Zhang, Dajian Zhu, Yan Lu, Jinhao Wu, Xueqing Yao

Pages: 1376-1386 Published online on: 11 February 2019

RBM3 upregulates ARPC2 by binding the 3'UTR and contributes to breast cancer progression

Ping Chen, Xiaoli Yue, Hongbing Xiong, Xiaohong Lu, Zhenling Ji

Pages: 1387-1397 Published online on: 28 January 2019

Lysyl oxidase assists tumor‑initiating cells to enhance angiogenesis in hepatocellular carcinoma

Min Yang, Jingtao Liu, Fei Wang, Zhihua Tian, Bo Ma, Zhongwu Li, Boqing Wang, Wei Zhao

Pages: 1398-1408 Published online on: 31 January 2019

Downregulation of protein disulfide‑isomerase A3 expression inhibits cell proliferation and induces apoptosis through STAT3 signaling in hepatocellular carcinoma

Ryota Kondo, Kousuke Ishino, Ryuichi Wada, Hideyuki Takata, Wei‑Xia Peng, Mitsuhiro Kudo, Shoko Kure, Yohei Kaneya, Nobuhiko Taniai, Hiroshi Yoshida, Zenya Naito

Pages: 1409-1421 Published online on: 04 February 2019

Efficacy of aflibercept with FOLFOX and maintenance with fluoropyrimidine as first‑line therapy for metastatic colorectal cancer: GERCOR VELVET phase II study

Benoist Chibaudel, Jean‑Baptiste Bachet, Thierry André, Dominique Auby, Jérôme Desramé, Gaël Deplanque, Cédric Lecaille, Christophe Louvet, Christophe Tournigand, Valérie Lebrun‑Ly, Jérôme Dauba, Gérard Lledo, Marie‑Line Garcia, Olivier Dubreuil, Nabil Baba Hamed, Aurélia Meurisse, Annette K. Larsen, Annemilaï Tijeras‑Raballand, Franck Bonnetain, Aimery De Gramont

Pages: 1433-1445 Published online on: 01 February 2019

Glyceryl trinitrate‑induced cytotoxicity of docetaxel‑resistant prostatic cancer cells is associated with differential regulation of clusterin

Sarra Bouaouiche, Lea Magadoux, Lucile Dondaine, Sylvie Reveneau, Nicolas Isambert, Ali Bettaieb, Jean‑François Jeannin, Veronique Laurens, Stephanie Plenchette

Pages: 1446-1456 Published online on: 01 February 2019

Netrin‑1 interference potentiates epithelial‑to‑mesenchymal transition through the PI3K/AKT pathway under the hypoxic microenvironment conditions of non‑small cell lung cancer

Xiayun Jin, Heqi Luan, Hua Chai, Lina Yan, Jing Zhang, Qi Wang, Lihua Cao

Pages: 1457-1465 Published online on: 15 February 2019

Adaptive EGF expression sensitizes pancreatic cancer cells to ionizing radiation through activation of the cyclin D1/P53/PARP pathway

Xiaoxing Liu, Haiyan Chen, Yanli Hou, Xiumei Ma, Ming Ye, Renhua Huang, Bin Hu, Hongbin Cao, Lei Xu, Mengyao Liu, Linfeng Li, Jianxin Gao, Yongrui Bai

Pages: 1466-1480 Published online on: 19 February 2019

Vitamin D and its low calcemic analogs modulate the anticancer properties of cisplatin and dacarbazine in the human melanoma A375 cell line

Anna Piotrowska, Justyna Wierzbicka, Agnieszka Rybarczyk, Robert C. Tuckey, Andrzej T. Slominski, Michał A. Żmijewski

Pages: 1481-1495 Published online on: 25 February 2019
Open Access

[Corrigendum] miR‑122 promotes proliferation and invasion of clear cell renal cell carcinoma by suppressing Forkhead box O3

Wenyuan Nie, Dong Ni, Xin Ma, Yu Zhang, Yu Gao, Cheng Peng, Xu Zhang

Pages: 1496-1496 Published online on: 23 January 2019
Journal Cover

Cover Legend PDF

April 2019
Volume 54 Issue 4

Print ISSN: 1019-6439
Online ISSN: 1791-2423

Sign up for eToc alerts

Recommend to Library

Full Size Image