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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2019 Volume 54 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Iron metabolism and its contribution to cancer (Review)

Ying Chen, Zhimin Fan, Ye Yang, Chunyan Gu
Pages: 1143-1154
Published online on: 20 February 2019

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Review

Mitochondrial calcium: Transport and modulation of cellular processes in homeostasis and cancer (Review)

Susana Romero-Garcia, Heriberto Prado-Garcia
Pages: 1155-1167
Published online on: 28 January 2019

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Article Open Access

Diverse and cancer type‑specific roles of the p53 R248Q gain‑of‑function mutation in cancer migration and invasiveness

Maciej Boleslaw Olszewski, Magdalena Pruszko, Ewa Snaar‑Jagalska, Alicja Zylicz, Maciej Zylicz
Pages: 1168-1182
Published online on: 22 February 2019

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Article Open Access

lncRNA PLAC2 activated by H3K27 acetylation promotes cell proliferation and invasion via the activation of Wnt/β‑catenin pathway in oral squamous cell carcinoma Retraction in /10.3892/ijo.2025.5743

Fubo Chen, Shengcai Qi, Xu Zhang, Jinjin Wu, Xi Yang, Raorao Wang
Pages: 1183-1194
Published online on: 01 February 2019

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Article Open Access

Silencing of COPB2 inhibits the proliferation of gastric cancer cells and induces apoptosis via suppression of the RTK signaling pathway

Caixia An, Hailong Li, Xueyan Zhang, Jing Wang, Yi Qiang, Xinhua Ye, Qiang Li, Quanlin Guan, Yongning Zhou
Pages: 1195-1208
Published online on: 18 February 2019

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Article Open Access

Comparison of tumor‑targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2

Anzhelika Vorobyeva, Alexey Sсhulga, Elena Konovalova, Rezan Güler, Bogdan Mitran, Javad Garousi, Sara Rinne, John Löfblom, Anna Orlova, Sergey Deyev, Vladimir Tolmachev
Pages: 1209-1220
Published online on: 11 February 2019

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Article Open Access

FABP5 regulates the proliferation of clear cell renal cell carcinoma cells via the PI3K/AKT signaling pathway

Qi Lv, Gangmin Wang, Yinan Zhang, Xiao Han, Haoming Li, Wei Le, Minguang Zhang, Chunhui Ma, Peijun Wang, Qiang Ding
Pages: 1221-1232
Published online on: 22 February 2019

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Article Open Access

Cathepsin B defines leader cells during the collective invasion of salivary adenoid cystic carcinoma

Jia‑Shun Wu, Zhu‑Feng Li, Hao‑Fan Wang, Xiang‑Hua Yu, Xin Pang, Jing‑Biao Wu, Sha‑Sha Wang, Mei Zhang, Xiao Yang, Ming‑Xin Cao, Ya‑Jie Tang, Xin‑Hua Liang, Min Zheng, Ya‑Ling Tang
Pages: 1233-1244
Published online on: 22 February 2019

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Article Open Access

Upregulation of microRNA‑194‑5p inhibits hypopharyngeal carcinoma cell proliferation, migration and invasion by targeting SMURF1 via the mTOR signaling pathway

Shan Xu, Lian Hui, Ning Yang, Yan Wang, Ning Zhao, Xue‑Jun Jiang
Pages: 1245-1255
Published online on: 04 February 2019

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Article Open Access

A novel mechanism for the anticancer activity of aspirin and salicylates

Asma'u I.J. Bashir, Chandra S. Kankipati, Sarah Jones, Robert M. Newman, Stephen T. Safrany, Christopher J. Perry, Iain D. Nicholl
Pages: 1256-1270
Published online on: 29 January 2019

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Article Open Access

Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling

Chi-Cheng Lu, Jo-Hua Chiang, Fuu-Jen Tsai, Yuan-Man Hsu, Yu-Ning Juan, Jai-Sing Yang, Hong-Yi Chiu
Pages: 1271-1281
Published online on: 30 January 2019

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Article Open Access

miR‑300 regulates tumor proliferation and metastasis by targeting lymphoid enhancer‑binding factor 1 in hepatocellular carcinoma

Yufo Chen, Yuanyuan Guo, Yawei Li, Jingwen Yang, Jing Liu, Qiong Wu, Rui Wang
Pages: 1282-1294
Published online on: 13 February 2019

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Article Open Access

CGK062, a small chemical molecule, inhibits cancer upregulated gene 2‑induced oncogenesis through NEK2 and β‑catenin

Sirichat Kaowinn, Sangtaek Oh, Jeong Moon, Ah Young Yoo, Ho Young Kang, Mi Rim Lee, Ji Eun Kim, Dae Youn Hwang, So Eun Youn, Sang Seok Koh, Young‑Hwa Chung
Pages: 1295-1305
Published online on: 22 February 2019

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Article

Triacetyl resveratrol upregulates miRNA‑200 and suppresses the Shh pathway in pancreatic cancer: A potential therapeutic agent

Junsheng Fu, Anju Shrivastava, Sushant K. Shrivastava, Rakesh K. Srivastava, Sharmila Shankar
Pages: 1306-1316
Published online on: 28 January 2019

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Article

Long non-coding RNA TUG1 recruits miR‑29c‑3p from its target gene RGS1 to promote proliferation and metastasis of melanoma cells

Yanqian Wang, Gang Liu, Lin Ren, Kun Wang, Aimin Liu
Pages: 1317-1326
Published online on: 28 January 2019

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Article

Runx3 inhibits endothelial progenitor cell differentiation and function via suppression of HIF-1α activity

So-Yun Choo, Soo-Hyun Yoon, Dong-Jin Lee, Sun Hee Lee, Kang Li, In Hye Koo, Wooin Lee, Suk-Chul Bae, You Mie Lee
Pages: 1327-1336
Published online on: 11 February 2019

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Article

COUP‑TFII promotes epithelial‑mesenchymal transition by inhibiting miR‑34a expression in colorectal cancer

Ying Bao, Yongliang Lu, Wenming Feng, Hongbin Yu, Huihui  Guo, Yulong Tao, Qian Shi, Wei Chen, Xiang Wang
Pages: 1337-1344
Published online on: 18 February 2019

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Article

Partial agonistic effect of cetuximab on epidermal growth factor receptor and Src kinase activation in triple‑negative breast cancer cell lines

Hakan Gurdal, Matilda Merve Tuglu, Saber Yari Bostanabad, Başak Dalkiliç
Pages: 1345-1356
Published online on: 28 January 2019

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Article

The proteasome inhibitor, bortezomib, induces prostate cancer cell death by suppressing the expression of prostate-specific membrane antigen, as well as androgen receptor

Kenji Kuroda, He Liu
Pages: 1357-1366
Published online on: 01 February 2019

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Article

MACC1 overexpression in carcinoma‑associated fibroblasts induces the invasion of lung adenocarcinoma cells via paracrine signaling

Zhuoshi Li, Tao Guo, Lei Fang, Nan Li, Xiaochao Wang, Peng Wang, Shilei Zhao, Fengzhou Li, Yanwei Cui, Xin Shu, Lei Zhao, Jinxiu Li, Chundong Gu
Pages: 1367-1375
Published online on: 30 January 2019

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Article

Protective effect of curcumin against irinotecan‑induced intestinal mucosal injury via attenuation of NF‑κB activation, oxidative stress and endoplasmic reticulum stress

Manzhao Ouyang, Zhentao Luo, Weijie Zhang, Dajian Zhu, Yan Lu, Jinhao Wu, Xueqing Yao
Pages: 1376-1386
Published online on: 11 February 2019

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Article

RBM3 upregulates ARPC2 by binding the 3'UTR and contributes to breast cancer progression

Ping Chen, Xiaoli Yue, Hongbing Xiong, Xiaohong Lu, Zhenling Ji
Pages: 1387-1397
Published online on: 28 January 2019

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Article

Lysyl oxidase assists tumor‑initiating cells to enhance angiogenesis in hepatocellular carcinoma

Min Yang, Jingtao Liu, Fei Wang, Zhihua Tian, Bo Ma, Zhongwu Li, Boqing Wang, Wei Zhao
Pages: 1398-1408
Published online on: 31 January 2019

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Article

Downregulation of protein disulfide‑isomerase A3 expression inhibits cell proliferation and induces apoptosis through STAT3 signaling in hepatocellular carcinoma

Ryota Kondo, Kousuke Ishino, Ryuichi Wada, Hideyuki Takata, Wei‑Xia Peng, Mitsuhiro Kudo, Shoko Kure, Yohei Kaneya, Nobuhiko Taniai, Hiroshi Yoshida, Zenya Naito
Pages: 1409-1421
Published online on: 04 February 2019

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Article

2,3,7,8‑tetrachlorodibenzo‑p‑dioxin suppresses the growth of human colorectal cancer cells in vitro: Implication of the aryl hydrocarbon receptor signaling

Masayoshi Yamaguchi, Oliver Hankinson
Pages: 1422-1432
Published online on: 30 January 2019

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Article

Efficacy of aflibercept with FOLFOX and maintenance with fluoropyrimidine as first‑line therapy for metastatic colorectal cancer: GERCOR VELVET phase II study

Benoist Chibaudel, Jean‑Baptiste Bachet, Thierry André, Dominique Auby, Jérôme Desramé, Gaël Deplanque, Cédric Lecaille, Christophe Louvet, Christophe Tournigand, Valérie Lebrun‑Ly, Jérôme Dauba, Gérard Lledo, Marie‑Line Garcia, Olivier Dubreuil, Nabil Baba Hamed, Aurélia Meurisse, Annette K. Larsen, Annemilaï Tijeras‑Raballand, Franck Bonnetain, Aimery De Gramont
Pages: 1433-1445
Published online on: 01 February 2019

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Article

Glyceryl trinitrate‑induced cytotoxicity of docetaxel‑resistant prostatic cancer cells is associated with differential regulation of clusterin

Sarra Bouaouiche, Lea Magadoux, Lucile Dondaine, Sylvie Reveneau, Nicolas Isambert, Ali Bettaieb, Jean‑François Jeannin, Veronique Laurens, Stephanie Plenchette
Pages: 1446-1456
Published online on: 01 February 2019

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Article

Netrin‑1 interference potentiates epithelial‑to‑mesenchymal transition through the PI3K/AKT pathway under the hypoxic microenvironment conditions of non‑small cell lung cancer

Xiayun Jin, Heqi Luan, Hua Chai, Lina Yan, Jing Zhang, Qi Wang, Lihua Cao
Pages: 1457-1465
Published online on: 15 February 2019

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Article

Adaptive EGF expression sensitizes pancreatic cancer cells to ionizing radiation through activation of the cyclin D1/P53/PARP pathway

Xiaoxing Liu, Haiyan Chen, Yanli Hou, Xiumei Ma, Ming Ye, Renhua Huang, Bin Hu, Hongbin Cao, Lei Xu, Mengyao Liu, Linfeng Li, Jianxin Gao, Yongrui Bai
Pages: 1466-1480
Published online on: 19 February 2019

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Article

Vitamin D and its low calcemic analogs modulate the anticancer properties of cisplatin and dacarbazine in the human melanoma A375 cell line

Anna Piotrowska, Justyna Wierzbicka, Agnieszka Rybarczyk, Robert C. Tuckey, Andrzej T. Slominski, Michał A. Żmijewski
Pages: 1481-1495
Published online on: 25 February 2019

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Correction Open Access

[Corrigendum] miR‑122 promotes proliferation and invasion of clear cell renal cell carcinoma by suppressing Forkhead box O3

Wenyuan Nie, Dong Ni, Xin Ma, Yu Zhang, Yu Gao, Cheng Peng, Xu Zhang
Pages: 1496-1496
Published online on: 23 January 2019

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Journal Cover
May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Role of histone modifications in gastric cancer (Review)

Ying Zhang, Lili Wang, Ling Wang, Zefen Li, Ruiying You, Xueping Meng, Yazhen Gao, Leyi Zhu, Shufei Wei, Meiren Li
Article Number: 65
Published online on: 30 March 2026

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Article

Selective antitumor and apoptosis‑inducing effects of the Src inhibitor PP1 in human tongue squamous cell carcinoma cells

Shirinbaeva Luiza Kantibekovna, Saini Wang, Hyunju Kang, Young-Min Shin, Byeong-Churl Jang
Article Number: 64
Published online on: 27 March 2026

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Review Open Access

Multifaceted roles of miR‑124 in cancer: Molecular mechanisms and clinical prospects (Review)

Jun Guo, Yunyan Guo, Peiyang Chen, Wenyan Xiao, Yuxiang Tan, Zhiyong Wang, Yanxin Lu, Xupeng Yue
Article Number: 63
Published online on: 24 March 2026

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Article Open Access

Hypoxia‑induced exosomal CAMTA1 promotes radio‑resistance in MDA‑MB‑231 cells by regulating NRG1 to mediate M2 macrophage polarization

Qian Li, Minghua Jiang, Biqing Zhu, Wei Wei, Lei Xia, Jian Huang, Han Gao, Mingyu Du
Article Number: 62
Published online on: 20 March 2026

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Correction Open Access

[Corrigendum] Epithelial protein lost in neoplasm‑α (EPLIN‑α) is a potential prognostic marker for the progression of epithelial ovarian cancer

Rong Liu, Tracey A. Martin, Nicola J. Jordan, Fiona Ruge, Lin Ye, Wen G. Jiang
Article Number: 61
Published online on: 18 March 2026

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Review Open Access

Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review)

Abdulaziz A. Aloliqi, Abdullah M. Alnuqaydan, Mohammad Alshebremi, Arshad Husain Rahmani, Amjad Ali Khan
Article Number: 60
Published online on: 18 March 2026

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Article Open Access

Smoking promotes colorectal cancer via the CKAP2L/AREG axis

Shasha Wu, Feixiang Wu, Xiaoqing Li, Zhihang Jiang, Fuqiang Liu, Zheng Jiang
Article Number: 59
Published online on: 13 March 2026

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Article Open Access

Diverse roles of SERPINE1 in regulating cellular proliferation and invasion

Wei Wang, Pengfei Zhao, Tian Wang, Weijing Wu, Jing Li, Qiang Huang, Jing Mo
Article Number: 58
Published online on: 13 March 2026

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Article Open Access

Therapeutic implications of targeting cancer testis antigen MAGEA1 in cervical cancer

Ayoung Kim, Jina Kim, Woori Kwak, Kyumin Mo, Soohyun Choe, Minyeong Jeon, Jisun Lee, Jun-Won Yun, Hyunho Yoon
Article Number: 57
Published online on: 12 March 2026

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Review Open Access

Enolase 1: A paradigm of metabolic enzyme moonlighting in tumorigenesis (Review)

Xiaochen Ni, Mingsi Zhang, Kaiyuan Zhang, Chuhang Wang, Jianing Guo, Wei Fan, Linfeng Zheng, Tao Jiang, Guangji Zhang
Article Number: 56
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Influence of MLH1 on colon cancer sensitivity to poly(ADP‑ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Article Number: 55
Published online on: 09 March 2026

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Review Open Access

Pancreatic cancer EMT‑targeted therapy: Molecular mechanisms and clinical translation (Review)

Guirui Zhang, Yongmo Wu, Mingzhen Wei, Shupeng Huang, Qinghao Wang, Zhengyi Xie, Sisi Liu, Jin Wang
Article Number: 54
Published online on: 06 March 2026

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Retraction Open Access

[Retracted] Design, synthesis and preclinical evaluation of NRC‑AN‑019

Kompella Amala, A.K.S. Bhujanga Rao, Bharathi Gorantla, Christopher S.  Gondi, Jasti S. Rao
Article Number: 53
Published online on: 04 March 2026

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Article Open Access

FOXM1 inhibitor, RCM‑1, enhances venetoclax mediated apoptosis through downregulation of ATP2B4 in rhabdomyosarcoma

Nawal Merjaneh, Ying-Wei Lan, Zicheng Deng, Johnny Donovan, Guolun Wang, Jonathan Do, Tiffany Juan, Xiaomei Xia, Vladimir V. Kalinichenko, Tanya V. Kalin
Article Number: 52
Published online on: 04 March 2026

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Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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Journal Cover
June-2026 Volume 68 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Antitumor activity of NRC‑AN‑019 in a pre‑clinical breast cancer model

Christopher S. Gondi, Bharathi Gorantla, A.K.S. Bhujanga Rao, K. Amala, M.U.R. Naidu, K.V. Jogi, G. Venkat Ramana, Praveen C. Myneni, Ajit Junnarkar, Jasti S. Rao
Article Number: 66
Published online on: 30 March 2026

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