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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2019 Volume 54 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Iron metabolism and its contribution to cancer (Review)

Ying Chen, Zhimin Fan, Ye Yang, Chunyan Gu
Pages: 1143-1154
Published online on: 20 February 2019

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Review

Mitochondrial calcium: Transport and modulation of cellular processes in homeostasis and cancer (Review)

Susana Romero-Garcia, Heriberto Prado-Garcia
Pages: 1155-1167
Published online on: 28 January 2019

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Article Open Access

Diverse and cancer type‑specific roles of the p53 R248Q gain‑of‑function mutation in cancer migration and invasiveness

Maciej Boleslaw Olszewski, Magdalena Pruszko, Ewa Snaar‑Jagalska, Alicja Zylicz, Maciej Zylicz
Pages: 1168-1182
Published online on: 22 February 2019

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Article Open Access

lncRNA PLAC2 activated by H3K27 acetylation promotes cell proliferation and invasion via the activation of Wnt/β‑catenin pathway in oral squamous cell carcinoma Retraction in /10.3892/ijo.2025.5743

Fubo Chen, Shengcai Qi, Xu Zhang, Jinjin Wu, Xi Yang, Raorao Wang
Pages: 1183-1194
Published online on: 01 February 2019

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Article Open Access

Silencing of COPB2 inhibits the proliferation of gastric cancer cells and induces apoptosis via suppression of the RTK signaling pathway

Caixia An, Hailong Li, Xueyan Zhang, Jing Wang, Yi Qiang, Xinhua Ye, Qiang Li, Quanlin Guan, Yongning Zhou
Pages: 1195-1208
Published online on: 18 February 2019

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Article Open Access

Comparison of tumor‑targeting properties of directly and indirectly radioiodinated designed ankyrin repeat protein (DARPin) G3 variants for molecular imaging of HER2

Anzhelika Vorobyeva, Alexey Sсhulga, Elena Konovalova, Rezan Güler, Bogdan Mitran, Javad Garousi, Sara Rinne, John Löfblom, Anna Orlova, Sergey Deyev, Vladimir Tolmachev
Pages: 1209-1220
Published online on: 11 February 2019

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Article Open Access

FABP5 regulates the proliferation of clear cell renal cell carcinoma cells via the PI3K/AKT signaling pathway

Qi Lv, Gangmin Wang, Yinan Zhang, Xiao Han, Haoming Li, Wei Le, Minguang Zhang, Chunhui Ma, Peijun Wang, Qiang Ding
Pages: 1221-1232
Published online on: 22 February 2019

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Article Open Access

Cathepsin B defines leader cells during the collective invasion of salivary adenoid cystic carcinoma

Jia‑Shun Wu, Zhu‑Feng Li, Hao‑Fan Wang, Xiang‑Hua Yu, Xin Pang, Jing‑Biao Wu, Sha‑Sha Wang, Mei Zhang, Xiao Yang, Ming‑Xin Cao, Ya‑Jie Tang, Xin‑Hua Liang, Min Zheng, Ya‑Ling Tang
Pages: 1233-1244
Published online on: 22 February 2019

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Article Open Access

Upregulation of microRNA‑194‑5p inhibits hypopharyngeal carcinoma cell proliferation, migration and invasion by targeting SMURF1 via the mTOR signaling pathway

Shan Xu, Lian Hui, Ning Yang, Yan Wang, Ning Zhao, Xue‑Jun Jiang
Pages: 1245-1255
Published online on: 04 February 2019

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Article Open Access

A novel mechanism for the anticancer activity of aspirin and salicylates

Asma'u I.J. Bashir, Chandra S. Kankipati, Sarah Jones, Robert M. Newman, Stephen T. Safrany, Christopher J. Perry, Iain D. Nicholl
Pages: 1256-1270
Published online on: 29 January 2019

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Article Open Access

Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling

Chi-Cheng Lu, Jo-Hua Chiang, Fuu-Jen Tsai, Yuan-Man Hsu, Yu-Ning Juan, Jai-Sing Yang, Hong-Yi Chiu
Pages: 1271-1281
Published online on: 30 January 2019

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Article Open Access

miR‑300 regulates tumor proliferation and metastasis by targeting lymphoid enhancer‑binding factor 1 in hepatocellular carcinoma

Yufo Chen, Yuanyuan Guo, Yawei Li, Jingwen Yang, Jing Liu, Qiong Wu, Rui Wang
Pages: 1282-1294
Published online on: 13 February 2019

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Article Open Access

CGK062, a small chemical molecule, inhibits cancer upregulated gene 2‑induced oncogenesis through NEK2 and β‑catenin

Sirichat Kaowinn, Sangtaek Oh, Jeong Moon, Ah Young Yoo, Ho Young Kang, Mi Rim Lee, Ji Eun Kim, Dae Youn Hwang, So Eun Youn, Sang Seok Koh, Young‑Hwa Chung
Pages: 1295-1305
Published online on: 22 February 2019

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Article

Triacetyl resveratrol upregulates miRNA‑200 and suppresses the Shh pathway in pancreatic cancer: A potential therapeutic agent

Junsheng Fu, Anju Shrivastava, Sushant K. Shrivastava, Rakesh K. Srivastava, Sharmila Shankar
Pages: 1306-1316
Published online on: 28 January 2019

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Article

Long non-coding RNA TUG1 recruits miR‑29c‑3p from its target gene RGS1 to promote proliferation and metastasis of melanoma cells

Yanqian Wang, Gang Liu, Lin Ren, Kun Wang, Aimin Liu
Pages: 1317-1326
Published online on: 28 January 2019

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Article

Runx3 inhibits endothelial progenitor cell differentiation and function via suppression of HIF-1α activity

So-Yun Choo, Soo-Hyun Yoon, Dong-Jin Lee, Sun Hee Lee, Kang Li, In Hye Koo, Wooin Lee, Suk-Chul Bae, You Mie Lee
Pages: 1327-1336
Published online on: 11 February 2019

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Article

COUP‑TFII promotes epithelial‑mesenchymal transition by inhibiting miR‑34a expression in colorectal cancer

Ying Bao, Yongliang Lu, Wenming Feng, Hongbin Yu, Huihui  Guo, Yulong Tao, Qian Shi, Wei Chen, Xiang Wang
Pages: 1337-1344
Published online on: 18 February 2019

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Article

Partial agonistic effect of cetuximab on epidermal growth factor receptor and Src kinase activation in triple‑negative breast cancer cell lines

Hakan Gurdal, Matilda Merve Tuglu, Saber Yari Bostanabad, Başak Dalkiliç
Pages: 1345-1356
Published online on: 28 January 2019

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Article

The proteasome inhibitor, bortezomib, induces prostate cancer cell death by suppressing the expression of prostate-specific membrane antigen, as well as androgen receptor

Kenji Kuroda, He Liu
Pages: 1357-1366
Published online on: 01 February 2019

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Article

MACC1 overexpression in carcinoma‑associated fibroblasts induces the invasion of lung adenocarcinoma cells via paracrine signaling

Zhuoshi Li, Tao Guo, Lei Fang, Nan Li, Xiaochao Wang, Peng Wang, Shilei Zhao, Fengzhou Li, Yanwei Cui, Xin Shu, Lei Zhao, Jinxiu Li, Chundong Gu
Pages: 1367-1375
Published online on: 30 January 2019

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Article

Protective effect of curcumin against irinotecan‑induced intestinal mucosal injury via attenuation of NF‑κB activation, oxidative stress and endoplasmic reticulum stress

Manzhao Ouyang, Zhentao Luo, Weijie Zhang, Dajian Zhu, Yan Lu, Jinhao Wu, Xueqing Yao
Pages: 1376-1386
Published online on: 11 February 2019

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Article

RBM3 upregulates ARPC2 by binding the 3'UTR and contributes to breast cancer progression

Ping Chen, Xiaoli Yue, Hongbing Xiong, Xiaohong Lu, Zhenling Ji
Pages: 1387-1397
Published online on: 28 January 2019

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Article

Lysyl oxidase assists tumor‑initiating cells to enhance angiogenesis in hepatocellular carcinoma

Min Yang, Jingtao Liu, Fei Wang, Zhihua Tian, Bo Ma, Zhongwu Li, Boqing Wang, Wei Zhao
Pages: 1398-1408
Published online on: 31 January 2019

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Article

Downregulation of protein disulfide‑isomerase A3 expression inhibits cell proliferation and induces apoptosis through STAT3 signaling in hepatocellular carcinoma

Ryota Kondo, Kousuke Ishino, Ryuichi Wada, Hideyuki Takata, Wei‑Xia Peng, Mitsuhiro Kudo, Shoko Kure, Yohei Kaneya, Nobuhiko Taniai, Hiroshi Yoshida, Zenya Naito
Pages: 1409-1421
Published online on: 04 February 2019

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Article

2,3,7,8‑tetrachlorodibenzo‑p‑dioxin suppresses the growth of human colorectal cancer cells in vitro: Implication of the aryl hydrocarbon receptor signaling

Masayoshi Yamaguchi, Oliver Hankinson
Pages: 1422-1432
Published online on: 30 January 2019

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Article

Efficacy of aflibercept with FOLFOX and maintenance with fluoropyrimidine as first‑line therapy for metastatic colorectal cancer: GERCOR VELVET phase II study

Benoist Chibaudel, Jean‑Baptiste Bachet, Thierry André, Dominique Auby, Jérôme Desramé, Gaël Deplanque, Cédric Lecaille, Christophe Louvet, Christophe Tournigand, Valérie Lebrun‑Ly, Jérôme Dauba, Gérard Lledo, Marie‑Line Garcia, Olivier Dubreuil, Nabil Baba Hamed, Aurélia Meurisse, Annette K. Larsen, Annemilaï Tijeras‑Raballand, Franck Bonnetain, Aimery De Gramont
Pages: 1433-1445
Published online on: 01 February 2019

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Article

Glyceryl trinitrate‑induced cytotoxicity of docetaxel‑resistant prostatic cancer cells is associated with differential regulation of clusterin

Sarra Bouaouiche, Lea Magadoux, Lucile Dondaine, Sylvie Reveneau, Nicolas Isambert, Ali Bettaieb, Jean‑François Jeannin, Veronique Laurens, Stephanie Plenchette
Pages: 1446-1456
Published online on: 01 February 2019

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Article

Netrin‑1 interference potentiates epithelial‑to‑mesenchymal transition through the PI3K/AKT pathway under the hypoxic microenvironment conditions of non‑small cell lung cancer

Xiayun Jin, Heqi Luan, Hua Chai, Lina Yan, Jing Zhang, Qi Wang, Lihua Cao
Pages: 1457-1465
Published online on: 15 February 2019

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Article

Adaptive EGF expression sensitizes pancreatic cancer cells to ionizing radiation through activation of the cyclin D1/P53/PARP pathway

Xiaoxing Liu, Haiyan Chen, Yanli Hou, Xiumei Ma, Ming Ye, Renhua Huang, Bin Hu, Hongbin Cao, Lei Xu, Mengyao Liu, Linfeng Li, Jianxin Gao, Yongrui Bai
Pages: 1466-1480
Published online on: 19 February 2019

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Article

Vitamin D and its low calcemic analogs modulate the anticancer properties of cisplatin and dacarbazine in the human melanoma A375 cell line

Anna Piotrowska, Justyna Wierzbicka, Agnieszka Rybarczyk, Robert C. Tuckey, Andrzej T. Slominski, Michał A. Żmijewski
Pages: 1481-1495
Published online on: 25 February 2019

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Correction Open Access

[Corrigendum] miR‑122 promotes proliferation and invasion of clear cell renal cell carcinoma by suppressing Forkhead box O3

Wenyuan Nie, Dong Ni, Xin Ma, Yu Zhang, Yu Gao, Cheng Peng, Xu Zhang
Pages: 1496-1496
Published online on: 23 January 2019

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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