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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2006 Volume 17 Issue 2

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Current status of genetic modulation of growth factors in wound repair (Review)

Katrin Riedel, Frank Riedel, Ulrich R. Goessler, Gisbert Holle, Günter Germann, Michael Sauerbier
Pages: 183-193
Published online on: 01 February 2006

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Review

Integrin β4, keratinocytes and papillomavirus infection (Review)

Monika Oldak, Sigrun Smola-Hess, Radoslaw Maksym
Pages: 195-202
Published online on: 01 February 2006

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Article

In vitro isolation of circulating endothelial progenitor cells is related to the high density lipoprotein plasma levels

Fabio Pellegatta, Marta Bragheri, Liliana Grigore, Sara Raselli, Franco Maria Maggi, Claudia Brambilla, Alice Reduzzi, Angela Pirillo, Giuseppe Danilo Norata, Alberico Luigi Catapano
Pages: 203-208
Published online on: 01 February 2006

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Article

Molecular cytogenetic characterization of the mouse cell line WMP2 by spectral karyotyping and multicolor banding applying murine probes

Constanze Karst, Vladimir Trifonov, Svetlana A. Romanenko, Uwe Claussen, Kristin Mrasek, Susanne Michel, Philip Avner, Thomas Liehr
Pages: 209-213
Published online on: 01 February 2006

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Article

Glycyrrhetic acid (a metabolic substance and aglycon of glycyrrhizin) induces apoptosis in human hepatoma, promyelotic leukemia and stomach cancer cells

Hiroshige Hibasami, Hirosi Iwase, Kazumi Yoshioka, Hidehisa Takahashi
Pages: 215-219
Published online on: 01 February 2006

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Article

COX-2 induction by heparanase in the progression of breast cancer

Takako Imada, Junji Matsuoka, Tetsuji Nobuhisa, Takaomi Okawa, Toshihiro Murata, Yoko Tabuchi, Yasuhiro Shirakawa, Nobuya Ohara, Mehmet Gunduz, Hitoshi Nagatsuka, Tatsuo Umeoka, Yasuhisa Yamamoto, Motowo Nakajima, Noriaki Tanaka, Yoshio Naomoto
Pages: 221-228
Published online on: 01 February 2006

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Article

Protective effect of geranylgeranylacetone on trinitrobenzene sulfonic acid-induced colitis in mice

Tatsuya Ohkawara, Jun Nishihira, Hiroshi Takeda, Takehiko Katsurada, Kanji Kato, Takashi Yoshiki, Toshiro Sugiyama, Masahiro Asaka
Pages: 229-234
Published online on: 01 February 2006

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Article

Vitamin K2-induced antitumor effects via cell-cycle arrest and apoptosis in gastric cancer cell lines

Hiromi Tokita, Akihiko Tsuchida, Keisuke Miyazawa, Kazuma Ohyashiki, Soh Katayanagi, Hideo Sudo, Masanobu Enomoto, Yu Takagi, Tatsuya Aoki
Pages: 235-243
Published online on: 01 February 2006

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Article

The selective cyclooxygenase-1 inhibitor SC-560 suppresses cell proliferation and induces apoptosis in human hepatocellular carcinoma cells

Nadia Lampiasi, Daniela Foderà, Natale D'Alessandro, Antonella Cusimano, Antonina Azzolina, Claudio Tripodo, Ada Maria Florena, Marta Ida Minervini, Monica Notarbartolo, Giuseppe Montalto, Melchiorre Cervello
Pages: 245-252
Published online on: 01 February 2006

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Article

A proteomics approach to characterizing human submandibular gland cell lines by fluorescent two-dimensional differential in-gel electrophoresis

Atsushi Kasamatsu, Katsuhiro Uzawa, Dai Nakashima, Yukinao Kouzu, Yosuke Endo, Hirofumi Koike, Hidetaka Yokoe, Koji Harada, Mitsunobu Sato, Hideki Tanzawa
Pages: 253-260
Published online on: 01 February 2006

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Article

Systematic analysis of cDNA microarray-based CGH

Chan Hee Park, Ha Jin Jeong, Yeon Ho Choi, Sang Cheol Kim, Hei Chul Jeong, Kyu Hyun Park, Gui Yeon Lee, Tae Soo Kim, Sang Wha Yang, Sung Whan Ahn, Yang Seok Kim, Sun Young Rha, Hyun Cheol Chung
Pages: 261-267
Published online on: 01 February 2006

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Article

Bacillus Calmette-Guérin induces the expression of peroxisome proliferator-activated receptor gamma in bladder cancer cells

Catalina Lodillinsky, María Sol Umerez, María Adela Jasnis, Alberto Casabé, Eduardo Sandes, Ana María Eiján
Pages: 269-273
Published online on: 01 February 2006

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Article

Assigning the phenotype of a natural regulatory T-cell to the human T-cell line, KARPAS-299

Carmen Wolke, Janine Tadje, Alicja Bukowska, Michael Täger, Ute Bank, Annelore Ittenson, Siegfried Ansorge, Uwe Lendeckel
Pages: 275-278
Published online on: 01 February 2006

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Article

Apoptotic potential of the concentrated effective microorganism fermentation extract on human cancer cells

Chung Hin Chui, Desmond Kwok Po Hau, Fung Yi Lau, Gregory Yin Ming Cheng, Raymond Siu Ming Wong, Roberto Gambari, Stanton Hon Lung Kok, Ka Bik Lai, Ivy Tuang Ngo Teo, Thomas Wai Tong Leung, Teruo Higa, Bin Ke, Johnny Cheuk On Tang, David Wan Fun Fong, Albert Sun Chi Chan
Pages: 279-284
Published online on: 01 February 2006

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Article

Alteration of gene expression in response to bone morphogenetic protein-2 in androgen-dependent human prostate cancer LNCaP cells

Toru Kumagai, Kentaro Tomari, Takahisa Shimizu, Ken Takeda
Pages: 285-291
Published online on: 01 February 2006

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Article

Quantitative correlation between cellular proliferation and nuclear poly (ADP-ribose) polymerase (PARP-1)

Ernest Kun, Eva Kirsten, Pal I. Bauer, Charles P. Ordahl
Pages: 293-300
Published online on: 01 February 2006

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Article

In vitro analysis of integrin expression during chondrogenic differentiation of mesenchymal stem cells and chondrocytes upon dedifferentiation in cell culture

Ulrich Reinhart Goessler, Karen Bieback, Peter Bugert, Tobias Heller, Haneen Sadick, Karl Hörmann, Frank Riedel
Pages: 301-307
Published online on: 01 February 2006

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Article

Use of bacteriophage in the treatment of experimental animal bacteremia from imipenem-resistant Pseudomonas aeruginosa

Jing Wang, Bei Hu, Minchao Xu, Qun Yan, Shuangyou Liu, Xuhui Zhu, Ziyong Sun, Eddie Reed, Li Ding, Jianping Gong, Qingdi Q. Li, Junbo Hu
Pages: 309-317
Published online on: 01 February 2006

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Article

Age-dependent decrease in the ghrelin gene expression in the human adrenal cortex: A real-time PCR study

Gianni Carraro, Giovanna Albertin, Francesco Aragona, Myriam Forneris, Valentina Casale, Raffaella Spinazzi, Gastone G. Nussdorfer
Pages: 319-321
Published online on: 01 February 2006

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Article

A novel histone deacetylase inhibitor, Scriptaid, induces growth inhibition, cell cycle arrest and apoptosis in human endometrial cancer and ovarian cancer cells

Noriyuki Takai, Tami Ueda, Masakazu Nishida, Kaei Nasu, Hisashi Narahara
Pages: 323-329
Published online on: 01 February 2006

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Article

The free radical scavengers edaravone and tempol suppress experimental dextran sulfate sodium-induced colitis in mice

Yoshio Araki, Hiroyuki Sugihara, Takanori Hattori
Pages: 331-334
Published online on: 01 February 2006

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Article

Late-onset and typical Huntington disease families from Crete have distinct genetic origins

Eleonora Kartsaki, Cleanthe Spanaki, Minas Tzagournissakis, Aphrodite Petsakou, Nicholas Moschonas, Marcy MacDonald, Andreas Plaitakis
Pages: 335-346
Published online on: 01 February 2006

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Article

Therapeutic effectiveness of bacteriophages in the rescue of mice with extended spectrum β-lactamase-producing Escherichia coli bacteremia

Jing Wang, Bei Hu, Minchao Xu, Qun Yan, Shuangyou Liu, Xuhui Zhu, Ziyong Sun, Deding Tao, Li Ding, Eddie Reed, Jianping Gong, Qingdi Q. Li, Junbo Hu
Pages: 347-355
Published online on: 01 February 2006

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Article

Etodolac, a selective cyclooxygenase-2 inhibitor, inhibits liver metastasis of colorectal cancer cells via the suppression of MMP-9 activity

Tetsuo Ishizaki, Kenji Katsumata, Akihiko Tsuchida, Tatehiko Wada, Yasuharu Mori, Masayuki Hisada, Hideaki Kawakita, Tatsuya Aoki
Pages: 357-362
Published online on: 01 February 2006

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Article

JDP1 (DNAJC12/Hsp40) expression in breast cancer and its association with estrogen receptor status

Simone Aparecida De Bessa, Sibeli Salaorni, Diogo F.C. Patrão, Mário Mourão Neto, Maria Mitzi Brentani, Maria Aparecida Nagai
Pages: 363-367
Published online on: 01 February 2006

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Article

Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure

Pál Pacher, Lucas Liaudet, Jon G. Mabley, Attila Cziráki, György Haskó, Csaba Szabó
Pages: 369-375
Published online on: 01 February 2006

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Article

Interleukin-10 does not affect IL-1-induced interleukin-6 and metalloproteinase production in human chondrosarcoma cells, SW1353

Jürgen Radons, Werner Falk, Thomas E.O. Schubert
Pages: 377-383
Published online on: 01 February 2006

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Article

Up-regulation of metallothionein isoforms in keloid keratinocytes

D. Lim, T. T. Phan, G. W. Yip, B. H. Bay
Pages: 385-389
Published online on: 01 February 2006

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Article

Comparative genomics on HHIP family orthologs

Yuriko Katoh, Masaru Katoh
Pages: 391-395
Published online on: 01 February 2006

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Article

H19-DMR allele-specific methylation analysis reveals epigenetic heterogeneity of CTCF binding site 6 but not of site 5 in head-and-neck carcinomas: A pilot case-control analysis

Leda Isabel De Castro Valente Esteves, Nilva De Karla Cervigne, Afonso Do Carmo Javaroni, José Magrin, Luiz Paulo Kowalski, Cláudia Aparecida Rainho, Silvia Regina Rogatto
Pages: 397-404
Published online on: 01 February 2006

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Journal Cover
October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of adipocytes and their derived extracellular vesicles in the progression, diagnosis and treatment of liver diseases (Review)

Kangrong Li, Muhammad Zubair, Yongmin Yan, Jiahao Xu
Article Number: 293
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin‑induced murine model of asthma

In Sik Shin, Mee Young Lee, Woo Young Jeon, Na Ra Shin, Chang Seob Seo, Hyekyung Ha
Article Number: 292
Published online on: 20 August 2026

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Review Open Access

Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review)

Denita Charoenthanakitkul, Chaiyaboot Ariyachet
Article Number: 291
Published online on: 20 August 2026

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Review Open Access

Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review)

Siqi Tang, Guoyou Gou, Youjia Liu, Fang Wang, Feihong Shu, Ya Deng, Ting Zhang, Jingyu Xu, Rui Xie
Article Number: 290
Published online on: 18 August 2026

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Review Open Access

Redox biology in PCOS: Biomarkers, mechanistic networks, and targeted interventions (Review)

Yuena Qiu, Xiaojing Guo, Jie An
Article Number: 289
Published online on: 18 August 2026

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Review Open Access

Glucose metabolism in osteoporosis: A potential therapeutic target (Review)

Shengyao Peng, Zhuo Yao, Junzhe Guo, Chi Zhang, Keda Yang, Lin Tao
Article Number: 288
Published online on: 17 August 2026

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Retraction Open Access

[Retracted] Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li
Article Number: 287
Published online on: 17 August 2026

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Article Open Access

α‑Cyperone targets the PAK1‑JNK/NF‑κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model

Hang Hu, Xing Wang, Linlin Guo, Ziling Zeng, Hongmei Tang, Yun Zhang, Jiayao Duan, Kaijin Wang
Article Number: 286
Published online on: 14 August 2026

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Article Open Access

Early high‑frequency spinal cord stimulation modulates the ROS/p38 MAPK/NF‑κB and CXCL10/CXCR3 pathways to alleviate neuropathic pain and promote spinal cord injury repair

Sitong Su, Tao Liu, Honghui Lei, Yang Yu, Caizhi Ma, Xinglang Wang, Haoyuan Chen, Zebin Huang, Meiling Cheng, Tongtong Qian, Fangyong Wang
Article Number: 285
Published online on: 13 August 2026

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Review Open Access

Shared mechanisms of musculoskeletal dysfunction in type 2 diabetes mellitus: Insights into future therapeutic directions (Review)

Zhenhong He, Hanyu Li, Yuhan Luo, Yingying Yu, Siyu Li, Tao Zhang, Dingsu Bao
Article Number: 284
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 283
Published online on: 12 August 2026

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Article Open Access

G protein‑coupled receptor kinase 4 governs early kidney development via STAT3 and Nhe3a

Linh Anna Trúc Vu, Julian Gerhards, Lars D. Maerz, Martin D. Burkhalter, Melanie Philipp
Article Number: 282
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Resistant starch prevents tumorigenesis of dimethylhydrazine‑induced colon tumors via regulation of an ER stress‑mediated mitochondrial apoptosis pathway  

Qiuyu Wang, Peng Wang, Zhigang Xiao
Article Number: 281
Published online on: 10 August 2026

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Review Open Access

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Ziwei Chen, Jiaqi Wu, Wenxi Liu, Jie Tan, Xiaochun Peng, Yanhua Zhang, Gai Liang
Article Number: 280
Published online on: 05 August 2026

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Review Open Access

Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review)

Xiu Yang, Pengcheng Li, Hao Zhao
Article Number: 279
Published online on: 05 August 2026

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Review Open Access

Contribution of p38 MAPK in liver fibrosis: An overview of mechanisms, signaling pathways, and therapeutic targets (Review)

Xueqin Yang, Huarong Li, Hao Ye, Ting Wu, Fangyun Xu, Chao Hu, Chunlei Yu, Pian Ye
Article Number: 278
Published online on: 05 August 2026

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Correction Open Access

[Corrigendum] Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 277
Published online on: 05 August 2026

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Review Open Access

Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review)

Chengzhi Liu, Qiong Wu, Mingzhen Yuan, Mingyue Liu, Xinyu Wang, Jiaqi Shen, Xusheng Cao
Article Number: 276
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Effects of miRNA‑455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Article Number: 275
Published online on: 03 August 2026

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Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

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Article Open Access

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

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Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

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Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

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Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

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Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Review Open Access

Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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November-2026 Volume 58 Issue 5

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Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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