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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2013 Volume 42 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Inhibition of repair-related DNA polymerases by vitamin Ks, their related quinone derivatives and associated inflammatory activity (Review)

Yoshiyuki Mizushina, Shin Nishiumi, Masayuki Nishida, Hiromi Yoshida, Takeshi Azuma, Masaru Yoshida
Pages: 793-802
Published online on: 15 January 2013

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Review

The RANKL/RANK system as a therapeutic target for bone invasion by oral squamous cell carcinoma (Review)

Eijiro Jimi, Masashi Shin, Hiroyuki Furuta, Yukiyo Tada, Jingo Kusukawa
Pages: 803-809
Published online on: 23 January 2013

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Article Open Access

Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondria

Sang Kyu Lee, Young Sang Kim
Pages: 810-816
Published online on: 23 January 2013

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Article Open Access

Delta-like 3 is silenced by methylation and induces apoptosis in human hepatocellular carcinoma

Kentaro Maemura, Hirohide Yoshikawa, Kazutake Yokoyama, Teruo Ueno, Hitomi Kurose, Kazuhisa Uchiyama, Yoshinori Otsuki
Pages: 817-822
Published online on: 17 January 2013

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Article Open Access

Biological characteristics of intratumoral [F-18]‑fluoromisonidazole distribution in a rodent model of glioma

Toshiyuki Hatano, Songji Zhao, Yan Zhao, Ken-Ichi Nishijima, Norihito  Kuno, Hiroko Hanzawa, Takeshi Sakamoto, Nagara Tamaki, Yuji Kuge
Pages: 823-830
Published online on: 18 January 2013

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Article Open Access

Identification of an H2-Kb or H2-Db restricted and glypican-3-derived cytotoxic T-lymphocyte epitope peptide

Tatsuaki Iwama, Kazutaka Horie, Toshiaki Yoshikawa, Daisuke Nobuoka, Manami Shimomura, Yu Sawada, Tetsuya Nakatsura
Pages: 831-838
Published online on: 23 January 2013

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Article Open Access

Nek2-targeted ASO or siRNA pretreatment enhances anticancer drug sensitivity in triple‑negative breast cancer cells

Jaehyung Lee, Lauren Gollahon
Pages: 839-847
Published online on: 22 January 2013

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Article Open Access

Microarray analysis of gene expression in vestibular schwannomas reveals SPP1/MET signaling pathway and androgen receptor deregulation

Miguel Torres-Martin, Luis Lassaletta, Jesus San-Roman-Montero, Jose  M. De Campos, Alberto Isla, Javier Gavilan, Barbara Melendez, Giovanny R. Pinto, Rommel R. Burbano, Javier S. Castresana, Juan A. Rey
Pages: 848-862
Published online on: 24 January 2013

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Article

Hydrogen peroxide induces cell death in human TRAIL-resistant melanoma through intracellular superoxide generation

Mizuki Tochigi, Toshio Inoue, Miki Suzuki-Karasaki, Toyoko Ochiai, Chisei Ra, Yoshihiro Suzuki-Karasaki
Pages: 863-872
Published online on: 10 January 2013

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Article

Functional analysis of Zyxin in cell migration and invasive potential of oral squamous cell carcinoma cells Corrigendum in /10.3892/ijo.2016.3702

Michiyo Yamamura, Kazuma Noguchi, Yoshiro Nakano, Emi Segawa, Yusuke Zushi, Kazuki Takaoka, Hiromitsu Kishimoto, Tomoko Hashimoto-Tamaoki, Masahiro Urade
Pages: 873-880
Published online on: 04 January 2013

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Article

The VHL tumor suppressor protein regulates tumorigenicity of U87-derived glioma stem-like cells by inhibiting the JAK/STAT signaling pathway

Hiroshi Kanno, Hidemitsu Sato, Taka-Akira Yokoyama, Tetsuya Yoshizumi, Sachiko Yamada
Pages: 881-886
Published online on: 16 January 2013

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Article

MUC5AC protects pancreatic cancer cells from TRAIL-induced death pathways

Hirotaka Hoshi, Tetsuji Sawada, Motoyuki Uchida, Hiroko Iijima, Kenjiro Kimura, Kosei Hirakawa, Hideki Wanibuchi
Pages: 887-893
Published online on: 03 January 2013

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Article

Loss of trefoil factor 1 is regulated by DNA methylation and is an independent predictive factor for poor survival in advanced gastric cancer

Tomokazu Tanaka, Jun Nakamura, Yoshihiko Kitajima, Keita Kai, Shuusuke Miyake, Masatsugu Hiraki, Takao Ide, Yasuo Koga, Hirokazu Noshiro
Pages: 894-902
Published online on: 03 January 2013

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Article

Clostridium butyricum MIYAIRI 588 shows antitumor effects by enhancing the release of TRAIL from neutrophils through MMP-8

Masahide Shinnoh, Mano Horinaka, Takashi Yasuda, Sae Yoshikawa, Mie Morita, Takeshi Yamada, Tsuneharu Miki, Toshiyuki Sakai
Pages: 903-911
Published online on: 23 January 2013

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Article

FKBP10/FKBP65 expression in high-grade ovarian serous carcinoma and its association with patient outcome

Michael C.J. Quinn, Paulina M. Wojnarowicz, Amy Pickett, Diane M. Provencher, Anne-Marie Mes-Masson, Elaine C. Davis, Patricia N. Tonin
Pages: 912-920
Published online on: 23 January 2013

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Article

PI3K/Akt and Stat3 signaling regulated by PTEN control of the cancer stem cell population, proliferation and senescence in a glioblastoma cell line

Seok-Ho Moon, Dae-Kwan Kim, Young Cha, Iksoo Jeon, Jihwan Song, Kyung-Soon Park
Pages: 921-928
Published online on: 10 January 2013

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Article

Extent of resection and radiotherapy in GBM: A 1973 to 2007 surveillance, epidemiology and end results analysis of 21,783 patients

Pascal O. Zinn, Rivka R. Colen, Ekkehard M. Kasper, Jan-Karl Burkhardt
Pages: 929-934
Published online on: 15 January 2013

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Article

Bortezomib-enhanced radiosensitization through the suppression of radiation-induced nuclear factor‑κB activity in human oral cancer cells

Tetsuya Tamatani, Natsumi Takamaru, Kanae Hara, Makoto Kinouchi, Nobuyuki Kuribayashi, Go Ohe, Daisuke Uchida, Kenji Fujisawa, Hirokazu Nagai, Youji Miyamoto
Pages: 935-944
Published online on: 22 January 2013

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Article

Effects of TRAIL and taurolidine on apoptosis and proliferation in human rhabdomyosarcoma, leiomyosarcoma and epithelioid cell sarcoma

C. Karlisch, K. Harati, A. M. Chromik, D. Bulut, L. Klein-Hitpass, O. Goertz, T. Hirsch, M. Lehnhardt, W. Uhl, A. Daigeler
Pages: 945-956
Published online on: 15 January 2013

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Article

MicroRNA-34b functions as a tumor suppressor and acts as a nodal point in the feedback loop with Met

Li-Guang Wang, Yang Ni, Ben-Hua Su, Xue-Ru Mu, Hong-Chang Shen, Jia-Jun Du
Pages: 957-962
Published online on: 10 January 2013

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Article

Picosecond pulsed electric fields induce apoptosis in HeLa cells via the endoplasmic reticulum stress and caspase-dependent signaling pathways

Wen-Juan Chen, Zheng-Ai Xiong, Min Zhang, Chen-Guo Yao, Zhong-Yong Zhao, Yuan-Yuan Hua, Wei Zhou
Pages: 963-970
Published online on: 16 January 2013

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Article

Total alkaloids of Rubus aleaefolius Poir inhibit hepatocellular carcinoma growth in vivo and in vitro via activation of mitochondrial-dependent apoptosis

Jinyan Zhao, Xuzheng Chen, Wei Lin, Guangwen Wu, Qunchuan Zhuang, Xiaoyong Zhong, Zhenfeng Hong, Jun Peng
Pages: 971-978
Published online on: 18 January 2013

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Article

Highly lymphatic metastatic pancreatic cancer cells possess stem cell-like properties

Guopei Luo, Jiang Long, Xiaobo Cui, Zhiwen Xiao, Zuqiang Liu, Si Shi, Liang Liu, Chen Liu, Jin Xu, Min Li, Xianjun Yu
Pages: 979-984
Published online on: 18 January 2013

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Article

Tat-SmacN7 induces radiosensitization in cancer cells through the activation of caspases and induction of apoptosis

Fenghua Chen, Chang Xu, Liqing Du, Yan Wang, Jia Cao, Yue Fu, Yanting Guo, Qiang Liu, Feiyue Fan
Pages: 985-992
Published online on: 22 January 2013

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Article

AKT serine/threonine protein kinase modulates baicalin-triggered autophagy in human bladder cancer T24 cells

Chingju Lin, Shih-Chang Tsai, Michael T. Tseng, Shu-Fen Peng, Sheng-Chu Kuo, Meng-Wei Lin, Yuan-Man Hsu, Miau-Rong Lee, Sakae Amagaya, Wen-Wen Huang, Tian-Shung Wu, Jai-Sing Yang
Pages: 993-1000
Published online on: 23 January 2013

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Article

S100A9 promotes the proliferation and invasion of HepG2 hepatocellular carcinoma cells via the activation of the MAPK signaling pathway Corrigendum in /10.3892/ijo.2023.5494

Rui Wu, Liang Duan, Liwei Ye, Haiyang Wang, Xia Yang, Yunyuan  Zhang, Xian Chen, Yan Zhang, Yaguang Weng, Jingyong  Luo, Min  Tang, Qiong Shi, Tongchuan He, Lan Zhou
Pages: 1001-1010
Published online on: 23 January 2013

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Article

CD133 glycosylation is enhanced by hypoxia in cultured glioma stem cells

Kristina S. Lehnus, Laura K. Donovan, Xiaowei Huang, Ninghui Zhao, Tracy J. Warr, Geoffrey J. Pilkington, Qian An
Pages: 1011-1017
Published online on: 22 January 2013

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Article

Hydrophobic flavonoids from Scutellaria baicalensis induce colorectal cancer cell apoptosis through a mitochondrial-mediated pathway

Chong-Zhi Wang, Tyler D. Calway, Xiao-Dong Wen, Jacob Smith, Chunhao  Yu, Yunwei Wang, Sangeeta R. Mehendale, Chun-Su Yuan
Pages: 1018-1026
Published online on: 16 January 2013

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Article

ERK1/2 activation mediated by the nutlin‑3‑induced mitochondrial translocation of p53

Sun-Young Lee, Seok Joon Shin, Ho-Shik Kim
Pages: 1027-1035
Published online on: 10 January 2013

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Article

Apoptosis induction of human prostate carcinoma cells by cordycepin through reactive oxygen species‑mediated mitochondrial death pathway

Hye Hyeon Lee, Cheol Park, Jin-Woo Jeong, Min Jeong Kim, Min Jeong Seo, Byoung Won Kang, Jeong Uck Park, Gi-Young Kim, Byung Tae Choi, Yung Hyun Choi, Yong Kee Jeong
Pages: 1036-1044
Published online on: 04 January 2013

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Article

Anacardic acid induces mitochondrial-mediated apoptosis in the A549 human lung adenocarcinoma cells

Yeong-Ae Seong, Pyung-Gyun Shin, Gun-Do Kim
Pages: 1045-1051
Published online on: 08 January 2013

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Article

Potent growth-inhibitory effect of a dual cancer-specific oncolytic adenovirus expressing apoptin on prostate carcinoma

Muchun Zhang, Jinhui Wang, Chang Li, Ningning Hu, Kai Wang, Huifan Ji, Dongyun He, Chengshi Quan, Xiao Li, Ningyi Jin, Yulin Li
Pages: 1052-1060
Published online on: 21 January 2013

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Article

A recombined fusion protein PTD-Grb2-SH2 inhibits the proliferation of breast cancer cells in vitro

Jikai Yin, Zhongliang Cai, Li Zhang, Jian Zhang, Xianli He, Xilin Du, Qing Wang, Jianguo Lu
Pages: 1061-1069
Published online on: 10 January 2013

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Article

Xiao Jin Wan, a traditional Chinese herbal formula, inhibits proliferation via arresting cell cycle progression at the G2/M phase and promoting apoptosis via activating the mitochondrial‑dependent pathway in U-2OS human osteosarcoma cells

Guangwen Wu, Jianfeng Chu, Zhengrong Huang, Jinxia Ye, Panyu Chen, Chunsong Zheng, Xihai Li, Xianxiang Liu, Mingxia Wu
Pages: 1070-1080
Published online on: 23 January 2013

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Article

A role for LRIG1 in the regulation of malignant glioma aggressiveness

Feng Mao, Baofeng Wang, Qungen Xiao, Guifa Xi, Wei Sun, Huaqiu Zhang, Fei Ye, Feng Wan, Dongsheng Guo, Ting Lei, Xiaoping Chen
Pages: 1081-1087
Published online on: 16 January 2013

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Article

Proteomic (antibody microarray) exploration of the molecular mechanism of action of the specific COX-2 inhibitor DuP 697

Vijay Agarwal, Victoria C. Hodgkinson, Gina L. Eagle, Lucy Scaife, Michael J. Lind, Lynn Cawkwell
Pages: 1088-1092
Published online on: 22 January 2013

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Article

Prostaglandin E2 promotes liver cancer cell growth by the upregulation of FUSE-binding protein 1 expression

Juan Ma, Meng Chen, Shu-Kai Xia, Wei Shu, Yan Guo, Yao-Hui Wang, Yan Xu, Xiao-Ming Bai, Li Zhang, Hai Zhang, Min Zhang, Yi-Pin Wang, Jing Leng
Pages: 1093-1104
Published online on: 18 January 2013

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Article

Molecular clone and functional study of a novel hepatoma associated gene

Yanhong Liu, Yanjie Zhao, Qiang Ju, Lin Chen, Feng Li, Guohua  Zhou, Pingli Xie, Guancheng Li, Yuehui Li
Pages: 1105-1112
Published online on: 10 January 2013

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Article

Leptin stimulates ovarian cancer cell growth and inhibits apoptosis by increasing cyclin D1 and Mcl-1 expression via the activation of the MEK/ERK1/2 and PI3K/Akt signaling pathways Corrigendum in /10.3892/ijo.2016.3564

Chiachen Chen, Yuan-Ching Chang, Michael S. Lan, Mary Breslin
Pages: 1113-1119
Published online on: 23 January 2013

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Article

EGCG inhibits recepteur d'origine nantais expression by suppressing Egr-1 in gastric cancer cells

Jung Sun Park, Pham Ngoc Khoi, Young Eun Joo, Young Han Lee, Sven A. Lang, Oliver Stoeltzing, Young Do Jung
Pages: 1120-1126
Published online on: 16 January 2013

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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