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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2017 Volume 15 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Chromolaena odorata: A neglected weed with a wide spectrum of pharmacological activities (Review)

Kavitha Vijayaraghavan, Johanna Rajkumar, Syed Nasir Abbas Bukhari, Badr Al‑Sayed, Mohammed Ali Seyed
Pages: 1007-1016
Published online on: 19 January 2017

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Review Open Access

Surgically‑induced mouse models in the study of bone regeneration: Current models and future directions (Review)

Bin Ning, Yunpeng Zhao, John A. Buza III, Wei Li, Wenzhao Wang, Tanghong Jia
Pages: 1017-1023
Published online on: 26 January 2017

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Article Open Access

Activity of fibroblast growth factor receptor inhibitors TKI258, ponatinib and AZD4547 against TPR‑FGFR1 fusion

Xu‑Hua Qiu, Feng Li, Hong‑Qin Cao, Jing‑Jing Shao, Jian‑Gang Mei, Han‑Qing Li, Yong‑Ping Zhai
Pages: 1024-1030
Published online on: 24 January 2017

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Article Open Access

Downregulation of microRNA‑34b is responsible for the elevation of blood pressure in spontaneously hypertensive rats

Fan Yang, Haiyu Li, Youyou Du, Qiangwei Shi, Luosha Zhao
Pages: 1031-1036
Published online on: 16 January 2017

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Article Open Access

MicroRNA-141 inhibits tumor growth and minimizes therapy resistance in colorectal cancer

Jun Ye, Zhen Wang, Jing Zhao, Wuzhen Chen, Dang Wu, Pin Wu, Jian Huang
Pages: 1037-1042
Published online on: 23 January 2017

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Article Open Access

Metabolomics study on primary dysmenorrhea patients during the luteal regression stage based on ultra performance liquid chromatography coupled with quadrupole‑time‑of‑flight mass spectrometry

Ling Fang, Caiyun Gu, Xinyu Liu, Jiabin Xie, Zhiguo Hou, Meng Tian, Jia Yin, Aizhu Li, Yubo Li
Pages: 1043-1050
Published online on: 13 January 2017

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Article Open Access

Identification of biomarkers of intrahepatic cholangiocarcinoma via integrated analysis of mRNA and miRNA microarray data

Yaqing Chen, Dan Liu, Pengfei Liu, Yajing Chen, Huiling Yu, Quan Zhang
Pages: 1051-1056
Published online on: 16 January 2017

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Article Open Access

TRIM37 promotes epithelial‑mesenchymal transition in colorectal cancer

Cheng‑En Hu, Jun Gan
Pages: 1057-1062
Published online on: 16 January 2017

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Article Open Access

Increased expression of PD‑L1 by the human papillomavirus 16 E7 oncoprotein inhibits anticancer immunity

Chaoqi Liu, Jiao Lu, Huiqun Tian, Wei Du, Lin Zhao, Jing Feng, Ding Yuan, Zhiying Li
Pages: 1063-1070
Published online on: 05 January 2017

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Article Open Access

IsomiR expression patterns in canonical and Dicer‑independent microRNAs

Tingming Liang, Jiafeng Yu, Chang Liu, Li Guo
Pages: 1071-1078
Published online on: 13 January 2017

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Article Open Access

Vitexin alleviates lipopolysaccharide‑induced islet cell injury by inhibiting HMGB1 release

Feifei Wang, Jiajing Yin, Yujin Ma, Hongwei Jiang, Yanbo Li
Pages: 1079-1086
Published online on: 12 January 2017

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Article Open Access

Integrated analysis of differentially expressed genes and pathways in triple‑negative breast cancer

Cancan Peng, Wenli Ma, Wei Xia, Wenling Zheng
Pages: 1087-1094
Published online on: 04 January 2017

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Article Open Access

Increased frequency of peripheral blood follicular helper T cells and elevated serum IL‑21 levels in patients with knee osteoarthritis

Yuxing Shan, Changlin Qi, Yijun Liu, Hui Gao, Ding Zhao, Yanfang Jiang
Pages: 1095-1102
Published online on: 19 January 2017

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Article Open Access

Interference with Tim-3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis Retraction in /10.3892/mmr.2025.13766

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Pages: 1103-1108
Published online on: 23 January 2017

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Article Open Access

Preparation and evaluation of microemulsion‑based transdermal delivery of Cistanche tubulosa phenylethanoid glycosides

Jianhua Yang, Huanhuan Xu, Shanshan Wu, Bowei Ju, Dandan Zhu, Yao Yan, Mei Wang, Junping Hu
Pages: 1109-1116
Published online on: 25 January 2017

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Article Open Access

5-ASA-loaded SiO2 nanoparticles-a novel drug delivery system targeting therapy on ulcerative colitis in mice

Haiying Tang, Dan Xiang, Feng Wang, Jingwei Mao, Xiaoyan Tan, Yingde Wang
Pages: 1117-1122
Published online on: 26 January 2017

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Article Open Access

Combination Twist1 and CA15-3 in axillary lymph nodes for breast cancer prognosis

Xiaowei Jiang, Dan Guo, Wenfang Li, Tianwu Yu, Jian Zhou, Jianping Gong
Pages: 1123-1134
Published online on: 23 January 2017

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Article Open Access

Dose‑dependent effect of lysozyme upon Candida albicans biofilm

Sarra Sebaa, Nicolas Hizette, Zahia Boucherit‑Otmani, Philippe Courtois
Pages: 1135-1142
Published online on: 25 January 2017

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Article Open Access

ATM participates in the regulation of viability and cell cycle via ellipticine in bladder cancer

Shuixiang Tao, Shuai Meng, Xiangyi Zheng, Liping Xie
Pages: 1143-1148
Published online on: 24 January 2017

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Article Open Access

Beneficial effects of sulfonamide‑based gallates on osteoblasts in vitro Corrigendum in /10.3892/mmr.2021.12152

Li Huang, Pan Jin, Xiao Lin, Cuiwu Lin, Li Zheng, Jinmin Zhao
Pages: 1149-1156
Published online on: 24 January 2017

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Article Open Access

Diagnosis for choroideremia in a large Chinese pedigree by next‑generation sequencing (NGS) and non‑invasive prenatal testing (NIPT)

Li Zhu, Jingliang Cheng, Boxu Zhou, Chunli Wei, Weichan Yang, Dong Jiang, Iqra Ijaz, Xiaojun Tan, Rui Chen, Junjiang Fu
Pages: 1157-1164
Published online on: 13 January 2017

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Article Open Access

Protective effects of physiological testosterone on advanced glycation end product‑induced injury in human endothelial cells

Yaping Xie, Dan Yu, Jiahua Wu, Lin Li
Pages: 1165-1171
Published online on: 19 January 2017

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Article Open Access

Knockdown of the differentially expressed gene TNFRSF12A inhibits hepatocellular carcinoma cell proliferation and migration in vitro

Tao Wang, Sicong Ma, Xingxing Qi, Xiaoyin Tang, Dan Cui, Zhi Wang, Jiachang Chi, Ping Li, Bo Zhai
Pages: 1172-1178
Published online on: 26 January 2017

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Article Open Access

Effect and mechanism of resveratrol on drug resistance in human bladder cancer cells

Shanshan Wang, Qian Meng, Qing Xie, Man Zhang
Pages: 1179-1187
Published online on: 12 January 2017

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Article Open Access

Resveratrol activates endogenous cardiac stem cells and improves myocardial regeneration following acute myocardial infarction

Lin Ling, Shaohua Gu, Yan Cheng
Pages: 1188-1194
Published online on: 25 January 2017

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Article Open Access

Moscatilin induces apoptosis of pancreatic cancer cells via reactive oxygen species and the JNK/SAPK pathway

Lei Zhang, Yuan Fang, Xue‑Feng Xu, Da‑Yong Jin
Pages: 1195-1203
Published online on: 25 January 2017

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Article Open Access

miR‑34c‑3p acts as a tumor suppressor gene in osteosarcoma by targeting MARCKS

Hongliang Liu, Pengxiao Su, Liqiang Zhi, Kai Zhao
Pages: 1204-1210
Published online on: 11 January 2017

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Article Open Access

MicroRNA expression signature and the therapeutic effect of the microRNA‑21 antagomir in hypertrophic scarring

Liang Guo, Kai Xu, Hongbo Yan, Haifeng Feng, Tao Wang, Linlin Chai, Guozheng Xu
Pages: 1211-1221
Published online on: 05 January 2017

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Article Open Access

Effect of ART1 on the proliferation and migration of mouse colon carcinoma CT26 cells in vivo

Jian‑Xia Xu, Wei Xiong, Zhen Zeng, Yi Tang, Ya‑Lan Wang, Ming Xiao, Ming Li, Qing Shu Li, Guang‑Lin Song, Jing Kuang
Pages: 1222-1228
Published online on: 26 January 2017

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Article Open Access

Urinary kidney injury molecule‑1 as an early diagnostic biomarker of obstructive acute kidney injury and development of a rapid detection method

Yingli Jin, Xiaona Shao, Bo Sun, Chunsheng Miao, Zhengqiang Li, Yan Shi
Pages: 1229-1235
Published online on: 05 January 2017

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Article Open Access

Proteomic analysis indicates the importance of TPM3 in esophageal squamous cell carcinoma invasion and metastasis

Shao-Bin Yu, Qin Gao, Wen-Wei Lin, Ming-Qiang Kang
Pages: 1236-1242
Published online on: 25 January 2017

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Article Open Access

Developmental expression of Toll‑like receptors in the guinea pig lung

Lingjie Ma, Jiali Yang, Li Yang, Juan Shi, Jing Xue, Yong Li, Xiaoming Liu
Pages: 1243-1251
Published online on: 17 January 2017

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Article Open Access

Systematic analysis of microarray datasets to identify Parkinson's disease‑associated pathways and genes

Yinling Feng, Xuefeng Wang
Pages: 1252-1262
Published online on: 16 January 2017

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Article Open Access

Niaspan inhibits diabetic retinopathy‑induced vascular inflammation by downregulating the tumor necrosis factor‑α pathway

Yang Wang, Xiangda Meng, Hua Yan
Pages: 1263-1271
Published online on: 25 January 2017

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Article Open Access

Protective effects of ethyl pyruvate on lipopolysaccharide‑induced acute lung injury through inhibition of autophagy in neutrophils

Qingteng Zhu, Hui Wang, Hairong Wang, Yong Luo, Yang Yu, Qirong Du, Aihua Fei, Shuming Pan
Pages: 1272-1278
Published online on: 13 January 2017

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Article Open Access

Effects of S100A6 gene silencing on the biological features of eutopic endometrial stromal cells and β‑catenin expression

Xiaoling Zhang, Zequn Liu, Meihong Chen, Qing Cao, Donghua Huang
Pages: 1279-1285
Published online on: 05 January 2017

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Article Open Access

The metastasis suppressor gene KISS-1 regulates osteosarcoma apoptosis and autophagy processes

Yiran Yin, Lian Tang, Lei Shi
Pages: 1286-1290
Published online on: 11 January 2017

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Article

Endothelial microparticles activate endothelial cells to facilitate the inflammatory response

Yiyun Liu, Ruyuan Zhang, Hongping Qu, Jun Wu, Lei Li, Yaoqing Tang
Pages: 1291-1296
Published online on: 12 January 2017

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Article

Overexpression of ILK promotes temozolomide resistance in glioma cells

Feng Liang, Bing Wang, Long Bao, Yin‑Sheng Zhao, Shi‑Min Zhang, Shu‑Qin Zhang
Pages: 1297-1304
Published online on: 26 January 2017

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Article

Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ

Xiao Zhai, Xiao Chen, Jiancan Lu, Yaping Zhang, Xuejun Sun, Qin Huang, Qijin Wang
Pages: 1305-1312
Published online on: 13 January 2017

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Article Open Access

Targeted introduction and effective expression of hFIX at the AAVS1 locus in mesenchymal stem cells

Shu‑Jun Li, Ying Luo, Le‑Meng Zhang, Wei Yang, Guo‑Gang Zhang
Pages: 1313-1318
Published online on: 19 January 2017

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Article

A novel pathway in NSCLC cells: miR‑191, targeting NFIA, is induced by chronic hypoxia, and promotes cell proliferation and migration

Jia Zhao, Cheng‑Rui Qiao, Zheng Ding, Yin‑Liang Sheng, Xiang‑Nan Li, Yang Yang, Deng‑Yan Zhu, Chun‑Yang Zhang, Dong‑Lei Liu, Kai Wu, Song Zhao
Pages: 1319-1325
Published online on: 04 January 2017

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Article Open Access

MicroRNA-410 regulates autophagy-related gene ATG16L1 expression and enhances chemosensitivity via autophagy inhibition in osteosarcoma

Ren Chen, Xiaohai Li, Bin He, Wei Hu
Pages: 1326-1334
Published online on: 26 January 2017

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Article

17β‑Estradiol treatment drives Sp1 to upregulate MALAT‑1 expression and epigenetically affects physiological processes in U2OS cells

Qiongying Hu, Shuiqin Li, Changjin Chen, Menglin Zhu, Yiming Chen, Ziyi Zhao
Pages: 1335-1342
Published online on: 12 January 2017

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Article

Homology modeling and identification of amino acids involved in the catalytic process of Mycobacterium tuberculosis serine acetyltransferase

Juanjuan Qiu, Shizhu Zang, Yufang Ma, Lawrence Owusu, Lei Zhou, Tao Jiang, Yi Xin
Pages: 1343-1347
Published online on: 26 January 2017

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Article

A clinical and molecular analysis of a patient with Emanuel syndrome

Jin‑Wen Luo, Huan Yang, Zhi‑Ping Tan, Ming Tu, Hong Luo, Yi‑Feng Yang, Li Xie
Pages: 1348-1352
Published online on: 05 January 2017

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Article

Differentiation of osteoblast‑like cells and ectopic bone formation induced by bone marrow stem cells transfected with chitosan nanoparticles containing plasmid‑BMP2 sequences

Zhang Qing Hong, Liu Meng Tao, Zhang Xiao Bin
Pages: 1353-1361
Published online on: 17 January 2017

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Article

BDNF regulates the expression and secretion of VEGF from osteoblasts via the TrkB/ERK1/2 signaling pathway during fracture healing

Zitao Zhang, Yan Zhang, Zhengnan Zhou, Hongfei Shi, Xusheng Qiu, Jin Xiong, Yixin Chen
Pages: 1362-1367
Published online on: 12 January 2017

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Article

Overexpression of GRP75 inhibits inflammation in a rat model of intracerebral hemorrhage

Lian‑Jie Lv, Jia Li, Hai‑Bo Qiao, Ben‑Jin Nie, Peng Lu, Feng Xue, Zhi‑Ming Zhang
Pages: 1368-1372
Published online on: 17 January 2017

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Article

Hypoxia-induced hsa-miR-101 promotes glycolysis by targeting TIGAR mRNA in clear cell renal cell carcinoma

Xiaochao Xu, Chao Liu, Jinku Bao
Pages: 1373-1378
Published online on: 24 January 2017

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Article

miR‑15a‑5p acts as an oncogene in renal cell carcinoma

Lu Jin, Yifan Li, Tao He, Jia Hu, Jiaju Liu, Mingwei Chen, Zeng Zhang, Yaoting Gui, Xiangming Mao, Shangqi Yang, Yongqing Lai
Pages: 1379-1386
Published online on: 16 January 2017

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Article

miRNA‑375 regulates the cell survival and apoptosis of human non‑small cell carcinoma by targeting HER2

Longqiang Cheng, Bingxiang Zhan, Peng Luo, Baolong Wang
Pages: 1387-1392
Published online on: 12 January 2017

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Article

Involvement of retinoblastoma-associated protein 48 during photodynamic therapy of cervical cancer cells

Shuxia Wu, Lijun Wang, Xingye Ren, Yulu Pan, Yan Peng, Xiaoyan Zou, Cuige Shi, Youzhong Zhang
Pages: 1393-1400
Published online on: 26 January 2017

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Article

hCLOCK induction by hypoxia promotes inflammatory responses by activating the NF‑κB pathway

Xiao Tang, Daqiao Guo, Changpo Lin, Zhenyu Shi, Ruizhe Qian, Weiguo Fu, Jianjun Liu, Xu Li, Longhua Fan
Pages: 1401-1406
Published online on: 17 January 2017

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Article

TNF‑α regulates apoptosis of human vascular smooth muscle cells through gap junctions

Mei Tang, Jun Fang
Pages: 1407-1411
Published online on: 05 January 2017

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Article

Lnc‑IL7R promotes the growth of fibroblast‑like synoviocytes through interaction with enhancer of zeste homolog 2 in rheumatoid arthritis

Zhao Ye, Juan Xu, Shukui Li, Cheng Cai, Tiejun Li, Lishan Sun
Pages: 1412-1418
Published online on: 26 January 2017

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Article

Protective role of microRNA-126 in intracerebral hemorrhage

Fangen Kong, Jianhui Zhou, Wenying Zhou, Yuanqing Guo, Guowei Li, Lukun Yang
Pages: 1419-1425
Published online on: 19 January 2017

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Article

Identification of a missense mutation in the tyrosinase gene in a Chinese family with oculocutaneous albinism type 1

Qian Lu, Lamei Yuan, Hongbo Xu, Xiangjun Huang, Zhijian Yang, Junhui Yi, Bin Ni, Yong Chen, Hao Deng
Pages: 1426-1430
Published online on: 23 January 2017

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Correction Open Access

[Corrigendum] 5‑bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2‑one induces apoptosis in T24 human bladder cancer cells through mitochondria-dependent signaling pathways

Guo‑Qiang Yu, Zhong‑Ling Dou, Zhao‑Hui Jia
Pages: 1431-1431
Published online on: 27 December 2016

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Journal Cover
August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Regulatory function of ten‑eleven translocation‑2 in transcriptional mechanisms of demethylated myeloma cells

Lenka Slavickova, Michaela Nemcova, Dominika Svehlova, Veronika Frybortova, Jirina Manakova, Eva Kriegova, Jiri Minarik, Katerina Smesny Trtkova
Article Number: 237
Published online on: 25 June 2026

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Article Open Access

Mulberroside A attenuates H2O2‑induced oxidative stress and barrier dysfunction in Caco‑2 cells through Nrf2/HO‑1‑associated antioxidant signaling

Jianxin Chen, Xiufeng Huang, Xi Chen, Wenhai Jin, Dawei Lin
Article Number: 236
Published online on: 25 June 2026

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Retraction Open Access

[Retracted] Puerarin promotes DUSP1 expression by regulating miR‑133a‑3p in breast cancer

Zhifeng Li, Weiwei Xu, Xiaoyan Ren, Jinhua Xu, Jianxin Chen
Article Number: 235
Published online on: 23 June 2026

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Article Open Access

Sulforaphane attenuates cisplatin‑induced acute kidney injury by inhibiting oxidative stress, inflammation and apoptosis via regulation of NRF2

Zeyu Wu, Mengting Lu, Lei Xu, Ming Luo, Limei Shan, Hongxia Xing, Wenwen Li, Junling Qian
Article Number: 234
Published online on: 19 June 2026

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Article Open Access

Effects of β‑hydroxybutyrate on restoring autophagic flux and mitochondrial function in macrophages exposed to oxidized low‑density lipoprotein

Weiguang Luo, Mei He, Huiling Wang
Article Number: 233
Published online on: 19 June 2026

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Review Open Access

Genetic and molecular mechanisms of hereditary thoracic aortic aneurysm and dissection (Review)

Xiaokang Wang, Qiwen Tan, Jingcheng Xu, Yunlin Yang, Haoyue Huang, Xiaomei Teng, Weihua Wu
Article Number: 232
Published online on: 18 June 2026

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Degraded sulfated galactan derived from Gracilaria fisheri induces immunogenic cell death in MDA‑MB‑231 cells

Tawut Rudtanatip, Yada Polsan, Waraporn Sakaew, Somsuda Somintara, Jenjiralai Phanphak, Jamal El‑Abid, Kanokpan Wongprasert, Choowadee Pariwatthanakun
Article Number: 231
Published online on: 17 June 2026

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Article

Irbesartan ameliorates high‑glucose‑induced epithelial‑mesenchymal transition by downregulating the expression of NLRP3 in HK‑2 cells

Qing Deng, Xiujuan Liu, Dan Wen, Yuhua Cheng, Qing Zhao, Yu Wang, Yu Xiang, Qinkai Chen, Jinlei Lv
Article Number: 230
Published online on: 17 June 2026

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A β‑1,3‑1,6‑glucan from Aureobasidium pullulans enhances apoptotic and autophagic pathways in colorectal cancer cells

Ji-Won Park, Gyeong Mim Mun, Tae Min Jo, Ji A Shin, Takao Kuge, Hisashi Kimoto, Jin-Kyung Kim
Article Number: 229
Published online on: 16 June 2026

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Growth pattern and molecular biological analysis of primary meningioma cell cultures under different conditions

Stefan Linsler, Anna-Lena Moroldo, Walter Schulz‑Schaeffer, Ralf Ketter, Joachim Oertel, Steffi Urbschat
Article Number: 228
Published online on: 12 June 2026

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Melatonin alleviates mitochondrial damage by regulating SIRT3‑mediated mitochondrial dynamics in granulosa cells under PCOS‑like conditions

Congcong Xie, Zehao Liu, Tong Chen, Hui Lu, Xiujia Zhang, Wenbo Yu, Jiaxin Zhang, Dandan Shang, Xueying Wang
Article Number: 227
Published online on: 11 June 2026

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Strontium‑based metal‑organic framework/alendronate‑silk fibroin hydrogels promote tendon‑bone interface healing

Tao Yang, Hanji Zhang, Mingjun Li, Yiming Ren, Yunbo Sun, Weiyu Hou, Mengqiang Tian
Article Number: 226
Published online on: 11 June 2026

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Retraction Open Access

[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Review Open Access

Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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Retraction Open Access

[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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September-2026 Volume 34 Issue 3

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Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Sedanolide alleviates LPS‑induced depressive‑like behaviors by modulating the C3a/C3aR signaling axis and microglial glycolysis

Shaocong Lu, Fangla Luo, Niqi Chen, Gongde Shi, Yeru Chen
Article Number: 257
Published online on: 16 July 2026

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Expression of Concern Open Access

[Expression of Concern] Chrysophanol inhibits proliferation and induces apoptosis through NF‑κB/cyclin D1 and NF‑κB/Bcl‑2 signaling cascade in breast cancer cell lines

Li Ren, Zhouping Li, Chunmei Dai, Danyu Zhao, Yanjie Wang, Chunyu Ma, Chun Liu
Article Number: 256
Published online on: 15 July 2026

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PCSK9 alleviates doxorubicin‑induced pyroptosis of cardiomyocytes

Chaochu Cui, Jinyu Zhao, Xiaoqian Li, Shengming Huang, Gang Liu, Xinhui Xu, Can Guo, Tiesuo Zhao, Jiang Du, Shipeng Li, Xianwei Wang, Jianbo Yang
Article Number: 255
Published online on: 14 July 2026

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From cell to disease: Regulatory networks and mechanisms of super‑enhancers in aging (Review)

Xiaodan Wang, Weiqian Deng, Shuangxi Tu, Haojun Tang, Kai Yin, Xiao Zhu
Article Number: 254
Published online on: 14 July 2026

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Retraction Open Access

[Retracted] Matrine‑induced apoptosis in Hep3B cells via the inhibition of MDM2

Ning Zhou, Jiequn Li, Ting Li, Guangshun Chen, Zhongqiang Zhang, Zhongzhou Si
Article Number: 253
Published online on: 13 July 2026

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Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review)

Lan Wang, Zhiyuan Ma, Bei Ji, Shuhui Liu, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 252
Published online on: 09 July 2026

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Leonurine inhibits the proliferation and metastasis of liver cancer cells by regulating the PI3K/AKT signaling pathway via epithelial‑mesenchymal transition

Bowen Hu, Maher Al Hussan, Jiakai Zhang, Peihao Wen, Changjun Huang, Yang Chen, Huanfei Ding
Article Number: 251
Published online on: 08 July 2026

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Correction Open Access

[Corrigendum] Resistin aggravates the expression of proinflammatory cytokines in cerulein‑stimulated AR42J pancreatic acinar cells

Chong-Yi Jiang, Wei Wang
Article Number: 250
Published online on: 08 July 2026

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A‑Raf: A serine/threonine protein kinase with important biological functions (Review)

Muhan Yang, Mengying Chen, Jinmei Wei, Yanling Li, Chen Long, Yan Lei, Yanhong Zhou
Article Number: 249
Published online on: 07 July 2026

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Gut dysbiosis‑derived butyrate loss predicts feeding intolerance: Multiomics evidence guiding nurse‑driven microbiota‑supportive interventions (Review)

Ling Wei, Xiaohua Kong, Yuying Li, Huixia Wu, Yirong Gan, Fang Sun
Article Number: 248
Published online on: 07 July 2026

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Retraction Open Access

[Retracted] Network pharmacology combined with experimental validation to investigate the effect of Rongjin Niantong Fang on chondrocyte apoptosis in knee osteoarthritis

Jun Chen, Ting Zhang, Qingqing Luo, Ruyi Wang, Yuting Dai, Zhenyuan Chen, Chutian Zhang, Xuzheng Chen, Guangwen Wu
Article Number: 247
Published online on: 06 July 2026

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Laggera alata attenuates LPS‑induced systemic inflammation and hepatic‑pulmonary injury by regulating PINK1/Parkin-associated mitophagy and macrophage polarization

Jiangcun Wei, Wen Zhong, Guangyun Zhou, Mingtao Huang, Xiaodong Huang, Jing Liang
Article Number: 246
Published online on: 02 July 2026

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Review Open Access

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review)

Yun Bai, Danhua Ma, Xi Yang, Min Wang
Article Number: 245
Published online on: 02 July 2026

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Review Open Access

Evolving role of biomarkers beyond prostate‑specific antigen in refining prostate cancer screening: From blood‑based tests to urinary and genetic markers (Review)

Luxi Li, Linyue Zhang, Zehong Li, Keqiang Chai, Weidong Ren
Article Number: 244
Published online on: 02 July 2026

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Nanocurcumin attenuates brain injury in rats with desert dry‑heat‑induced exertional heat stroke by suppressing TLR4/MyD88/NF‑κB signaling

Lisong Su, Jinquan Qu, Jiajia Li, Wenhui Shi, Laiyang Song, Feixing Liang, Jiangwei Liu
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

TREM2 in glioma: Reprogramming the immune microenvironment from mechanistic understanding to clinical translation (Review)

Junqi Fan, Hongyan Shen, Dan Liu, Songbai Luo, Qingqing Huang, Yi Wen, Libang Yuan
Article Number: 242
Published online on: 02 July 2026

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Human parvovirus B19 VP1u‑induced osteoclastogenesis is enhanced by RANKL in RAW264.7 macrophage cells

Chun-Yu Lin, Bor-Show Tzang, Yi-Hsuan Lin, Chih-Chen Tzang, Tsai-Ching Hsu
Article Number: 241
Published online on: 30 June 2026

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Retraction Open Access

[Retracted] Anti‑tumor peptide AP25 decreases cyclin D1 expression and inhibits MGC‑803 proliferation via phospho­extracellular signal‑regulated kinase‑, Src‑, c‑Jun N‑terminal kinase‑ and phosphoinositide 3­-kinase‑associated pathways  

Jialiang Hu, Tao Cheng, Lijun Zhang, Beicheng Sun, Lei Deng, Hanmei Xu
Article Number: 240
Published online on: 29 June 2026

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Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats

Siqi Yan, Yuan Ren, Bingyan Liu, Pai Xiong, Yimin Sun
Article Number: 239
Published online on: 29 June 2026

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Morinda officinalis oligosaccharides ameliorate corticosterone‑induced depression‑like behaviour in mice by modulating the BDNF signalling pathway and gut microbiota

Mengjie He, Zixuan Liu, Yuxin Chen, Xiaoru Wu, Xueling Dai, Qian Liu, Shuo Wang, Zeping Zuo, Yaxuan Sun
Article Number: 238
Published online on: 29 June 2026

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