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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2017 Volume 15 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Chromolaena odorata: A neglected weed with a wide spectrum of pharmacological activities (Review)

Kavitha Vijayaraghavan, Johanna Rajkumar, Syed Nasir Abbas Bukhari, Badr Al‑Sayed, Mohammed Ali Seyed
Pages: 1007-1016
Published online on: 19 January 2017

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Review Open Access

Surgically‑induced mouse models in the study of bone regeneration: Current models and future directions (Review)

Bin Ning, Yunpeng Zhao, John A. Buza III, Wei Li, Wenzhao Wang, Tanghong Jia
Pages: 1017-1023
Published online on: 26 January 2017

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Article Open Access

Activity of fibroblast growth factor receptor inhibitors TKI258, ponatinib and AZD4547 against TPR‑FGFR1 fusion

Xu‑Hua Qiu, Feng Li, Hong‑Qin Cao, Jing‑Jing Shao, Jian‑Gang Mei, Han‑Qing Li, Yong‑Ping Zhai
Pages: 1024-1030
Published online on: 24 January 2017

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Article Open Access

Downregulation of microRNA‑34b is responsible for the elevation of blood pressure in spontaneously hypertensive rats

Fan Yang, Haiyu Li, Youyou Du, Qiangwei Shi, Luosha Zhao
Pages: 1031-1036
Published online on: 16 January 2017

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Article Open Access

MicroRNA-141 inhibits tumor growth and minimizes therapy resistance in colorectal cancer

Jun Ye, Zhen Wang, Jing Zhao, Wuzhen Chen, Dang Wu, Pin Wu, Jian Huang
Pages: 1037-1042
Published online on: 23 January 2017

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Article Open Access

Metabolomics study on primary dysmenorrhea patients during the luteal regression stage based on ultra performance liquid chromatography coupled with quadrupole‑time‑of‑flight mass spectrometry

Ling Fang, Caiyun Gu, Xinyu Liu, Jiabin Xie, Zhiguo Hou, Meng Tian, Jia Yin, Aizhu Li, Yubo Li
Pages: 1043-1050
Published online on: 13 January 2017

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Article Open Access

Identification of biomarkers of intrahepatic cholangiocarcinoma via integrated analysis of mRNA and miRNA microarray data

Yaqing Chen, Dan Liu, Pengfei Liu, Yajing Chen, Huiling Yu, Quan Zhang
Pages: 1051-1056
Published online on: 16 January 2017

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Article Open Access

TRIM37 promotes epithelial‑mesenchymal transition in colorectal cancer

Cheng‑En Hu, Jun Gan
Pages: 1057-1062
Published online on: 16 January 2017

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Article Open Access

Increased expression of PD‑L1 by the human papillomavirus 16 E7 oncoprotein inhibits anticancer immunity

Chaoqi Liu, Jiao Lu, Huiqun Tian, Wei Du, Lin Zhao, Jing Feng, Ding Yuan, Zhiying Li
Pages: 1063-1070
Published online on: 05 January 2017

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Article Open Access

IsomiR expression patterns in canonical and Dicer‑independent microRNAs

Tingming Liang, Jiafeng Yu, Chang Liu, Li Guo
Pages: 1071-1078
Published online on: 13 January 2017

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Article Open Access

Vitexin alleviates lipopolysaccharide‑induced islet cell injury by inhibiting HMGB1 release

Feifei Wang, Jiajing Yin, Yujin Ma, Hongwei Jiang, Yanbo Li
Pages: 1079-1086
Published online on: 12 January 2017

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Article Open Access

Integrated analysis of differentially expressed genes and pathways in triple‑negative breast cancer

Cancan Peng, Wenli Ma, Wei Xia, Wenling Zheng
Pages: 1087-1094
Published online on: 04 January 2017

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Article Open Access

Increased frequency of peripheral blood follicular helper T cells and elevated serum IL‑21 levels in patients with knee osteoarthritis

Yuxing Shan, Changlin Qi, Yijun Liu, Hui Gao, Ding Zhao, Yanfang Jiang
Pages: 1095-1102
Published online on: 19 January 2017

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Article Open Access

Interference with Tim-3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis Retraction in /10.3892/mmr.2025.13766

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Pages: 1103-1108
Published online on: 23 January 2017

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Article Open Access

Preparation and evaluation of microemulsion‑based transdermal delivery of Cistanche tubulosa phenylethanoid glycosides

Jianhua Yang, Huanhuan Xu, Shanshan Wu, Bowei Ju, Dandan Zhu, Yao Yan, Mei Wang, Junping Hu
Pages: 1109-1116
Published online on: 25 January 2017

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Article Open Access

5-ASA-loaded SiO2 nanoparticles-a novel drug delivery system targeting therapy on ulcerative colitis in mice

Haiying Tang, Dan Xiang, Feng Wang, Jingwei Mao, Xiaoyan Tan, Yingde Wang
Pages: 1117-1122
Published online on: 26 January 2017

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Article Open Access

Combination Twist1 and CA15-3 in axillary lymph nodes for breast cancer prognosis

Xiaowei Jiang, Dan Guo, Wenfang Li, Tianwu Yu, Jian Zhou, Jianping Gong
Pages: 1123-1134
Published online on: 23 January 2017

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Article Open Access

Dose‑dependent effect of lysozyme upon Candida albicans biofilm

Sarra Sebaa, Nicolas Hizette, Zahia Boucherit‑Otmani, Philippe Courtois
Pages: 1135-1142
Published online on: 25 January 2017

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Article Open Access

ATM participates in the regulation of viability and cell cycle via ellipticine in bladder cancer

Shuixiang Tao, Shuai Meng, Xiangyi Zheng, Liping Xie
Pages: 1143-1148
Published online on: 24 January 2017

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Article Open Access

Beneficial effects of sulfonamide‑based gallates on osteoblasts in vitro Corrigendum in /10.3892/mmr.2021.12152

Li Huang, Pan Jin, Xiao Lin, Cuiwu Lin, Li Zheng, Jinmin Zhao
Pages: 1149-1156
Published online on: 24 January 2017

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Article Open Access

Diagnosis for choroideremia in a large Chinese pedigree by next‑generation sequencing (NGS) and non‑invasive prenatal testing (NIPT)

Li Zhu, Jingliang Cheng, Boxu Zhou, Chunli Wei, Weichan Yang, Dong Jiang, Iqra Ijaz, Xiaojun Tan, Rui Chen, Junjiang Fu
Pages: 1157-1164
Published online on: 13 January 2017

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Article Open Access

Protective effects of physiological testosterone on advanced glycation end product‑induced injury in human endothelial cells

Yaping Xie, Dan Yu, Jiahua Wu, Lin Li
Pages: 1165-1171
Published online on: 19 January 2017

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Article Open Access

Knockdown of the differentially expressed gene TNFRSF12A inhibits hepatocellular carcinoma cell proliferation and migration in vitro

Tao Wang, Sicong Ma, Xingxing Qi, Xiaoyin Tang, Dan Cui, Zhi Wang, Jiachang Chi, Ping Li, Bo Zhai
Pages: 1172-1178
Published online on: 26 January 2017

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Article Open Access

Effect and mechanism of resveratrol on drug resistance in human bladder cancer cells

Shanshan Wang, Qian Meng, Qing Xie, Man Zhang
Pages: 1179-1187
Published online on: 12 January 2017

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Article Open Access

Resveratrol activates endogenous cardiac stem cells and improves myocardial regeneration following acute myocardial infarction

Lin Ling, Shaohua Gu, Yan Cheng
Pages: 1188-1194
Published online on: 25 January 2017

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Article Open Access

Moscatilin induces apoptosis of pancreatic cancer cells via reactive oxygen species and the JNK/SAPK pathway

Lei Zhang, Yuan Fang, Xue‑Feng Xu, Da‑Yong Jin
Pages: 1195-1203
Published online on: 25 January 2017

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Article Open Access

miR‑34c‑3p acts as a tumor suppressor gene in osteosarcoma by targeting MARCKS

Hongliang Liu, Pengxiao Su, Liqiang Zhi, Kai Zhao
Pages: 1204-1210
Published online on: 11 January 2017

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Article Open Access

MicroRNA expression signature and the therapeutic effect of the microRNA‑21 antagomir in hypertrophic scarring

Liang Guo, Kai Xu, Hongbo Yan, Haifeng Feng, Tao Wang, Linlin Chai, Guozheng Xu
Pages: 1211-1221
Published online on: 05 January 2017

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Article Open Access

Effect of ART1 on the proliferation and migration of mouse colon carcinoma CT26 cells in vivo

Jian‑Xia Xu, Wei Xiong, Zhen Zeng, Yi Tang, Ya‑Lan Wang, Ming Xiao, Ming Li, Qing Shu Li, Guang‑Lin Song, Jing Kuang
Pages: 1222-1228
Published online on: 26 January 2017

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Article Open Access

Urinary kidney injury molecule‑1 as an early diagnostic biomarker of obstructive acute kidney injury and development of a rapid detection method

Yingli Jin, Xiaona Shao, Bo Sun, Chunsheng Miao, Zhengqiang Li, Yan Shi
Pages: 1229-1235
Published online on: 05 January 2017

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Article Open Access

Proteomic analysis indicates the importance of TPM3 in esophageal squamous cell carcinoma invasion and metastasis

Shao-Bin Yu, Qin Gao, Wen-Wei Lin, Ming-Qiang Kang
Pages: 1236-1242
Published online on: 25 January 2017

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Article Open Access

Developmental expression of Toll‑like receptors in the guinea pig lung

Lingjie Ma, Jiali Yang, Li Yang, Juan Shi, Jing Xue, Yong Li, Xiaoming Liu
Pages: 1243-1251
Published online on: 17 January 2017

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Article Open Access

Systematic analysis of microarray datasets to identify Parkinson's disease‑associated pathways and genes

Yinling Feng, Xuefeng Wang
Pages: 1252-1262
Published online on: 16 January 2017

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Article Open Access

Niaspan inhibits diabetic retinopathy‑induced vascular inflammation by downregulating the tumor necrosis factor‑α pathway

Yang Wang, Xiangda Meng, Hua Yan
Pages: 1263-1271
Published online on: 25 January 2017

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Article Open Access

Protective effects of ethyl pyruvate on lipopolysaccharide‑induced acute lung injury through inhibition of autophagy in neutrophils

Qingteng Zhu, Hui Wang, Hairong Wang, Yong Luo, Yang Yu, Qirong Du, Aihua Fei, Shuming Pan
Pages: 1272-1278
Published online on: 13 January 2017

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Article Open Access

Effects of S100A6 gene silencing on the biological features of eutopic endometrial stromal cells and β‑catenin expression

Xiaoling Zhang, Zequn Liu, Meihong Chen, Qing Cao, Donghua Huang
Pages: 1279-1285
Published online on: 05 January 2017

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Article Open Access

The metastasis suppressor gene KISS-1 regulates osteosarcoma apoptosis and autophagy processes

Yiran Yin, Lian Tang, Lei Shi
Pages: 1286-1290
Published online on: 11 January 2017

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Article

Endothelial microparticles activate endothelial cells to facilitate the inflammatory response

Yiyun Liu, Ruyuan Zhang, Hongping Qu, Jun Wu, Lei Li, Yaoqing Tang
Pages: 1291-1296
Published online on: 12 January 2017

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Article

Overexpression of ILK promotes temozolomide resistance in glioma cells

Feng Liang, Bing Wang, Long Bao, Yin‑Sheng Zhao, Shi‑Min Zhang, Shu‑Qin Zhang
Pages: 1297-1304
Published online on: 26 January 2017

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Article

Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ

Xiao Zhai, Xiao Chen, Jiancan Lu, Yaping Zhang, Xuejun Sun, Qin Huang, Qijin Wang
Pages: 1305-1312
Published online on: 13 January 2017

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Article Open Access

Targeted introduction and effective expression of hFIX at the AAVS1 locus in mesenchymal stem cells

Shu‑Jun Li, Ying Luo, Le‑Meng Zhang, Wei Yang, Guo‑Gang Zhang
Pages: 1313-1318
Published online on: 19 January 2017

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Article

A novel pathway in NSCLC cells: miR‑191, targeting NFIA, is induced by chronic hypoxia, and promotes cell proliferation and migration

Jia Zhao, Cheng‑Rui Qiao, Zheng Ding, Yin‑Liang Sheng, Xiang‑Nan Li, Yang Yang, Deng‑Yan Zhu, Chun‑Yang Zhang, Dong‑Lei Liu, Kai Wu, Song Zhao
Pages: 1319-1325
Published online on: 04 January 2017

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Article Open Access

MicroRNA-410 regulates autophagy-related gene ATG16L1 expression and enhances chemosensitivity via autophagy inhibition in osteosarcoma

Ren Chen, Xiaohai Li, Bin He, Wei Hu
Pages: 1326-1334
Published online on: 26 January 2017

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Article

17β‑Estradiol treatment drives Sp1 to upregulate MALAT‑1 expression and epigenetically affects physiological processes in U2OS cells

Qiongying Hu, Shuiqin Li, Changjin Chen, Menglin Zhu, Yiming Chen, Ziyi Zhao
Pages: 1335-1342
Published online on: 12 January 2017

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Article

Homology modeling and identification of amino acids involved in the catalytic process of Mycobacterium tuberculosis serine acetyltransferase

Juanjuan Qiu, Shizhu Zang, Yufang Ma, Lawrence Owusu, Lei Zhou, Tao Jiang, Yi Xin
Pages: 1343-1347
Published online on: 26 January 2017

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Article

A clinical and molecular analysis of a patient with Emanuel syndrome

Jin‑Wen Luo, Huan Yang, Zhi‑Ping Tan, Ming Tu, Hong Luo, Yi‑Feng Yang, Li Xie
Pages: 1348-1352
Published online on: 05 January 2017

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Article

Differentiation of osteoblast‑like cells and ectopic bone formation induced by bone marrow stem cells transfected with chitosan nanoparticles containing plasmid‑BMP2 sequences

Zhang Qing Hong, Liu Meng Tao, Zhang Xiao Bin
Pages: 1353-1361
Published online on: 17 January 2017

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Article

BDNF regulates the expression and secretion of VEGF from osteoblasts via the TrkB/ERK1/2 signaling pathway during fracture healing

Zitao Zhang, Yan Zhang, Zhengnan Zhou, Hongfei Shi, Xusheng Qiu, Jin Xiong, Yixin Chen
Pages: 1362-1367
Published online on: 12 January 2017

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Article

Overexpression of GRP75 inhibits inflammation in a rat model of intracerebral hemorrhage

Lian‑Jie Lv, Jia Li, Hai‑Bo Qiao, Ben‑Jin Nie, Peng Lu, Feng Xue, Zhi‑Ming Zhang
Pages: 1368-1372
Published online on: 17 January 2017

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Article

Hypoxia-induced hsa-miR-101 promotes glycolysis by targeting TIGAR mRNA in clear cell renal cell carcinoma

Xiaochao Xu, Chao Liu, Jinku Bao
Pages: 1373-1378
Published online on: 24 January 2017

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Article

miR‑15a‑5p acts as an oncogene in renal cell carcinoma

Lu Jin, Yifan Li, Tao He, Jia Hu, Jiaju Liu, Mingwei Chen, Zeng Zhang, Yaoting Gui, Xiangming Mao, Shangqi Yang, Yongqing Lai
Pages: 1379-1386
Published online on: 16 January 2017

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Article

miRNA‑375 regulates the cell survival and apoptosis of human non‑small cell carcinoma by targeting HER2

Longqiang Cheng, Bingxiang Zhan, Peng Luo, Baolong Wang
Pages: 1387-1392
Published online on: 12 January 2017

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Article

Involvement of retinoblastoma-associated protein 48 during photodynamic therapy of cervical cancer cells

Shuxia Wu, Lijun Wang, Xingye Ren, Yulu Pan, Yan Peng, Xiaoyan Zou, Cuige Shi, Youzhong Zhang
Pages: 1393-1400
Published online on: 26 January 2017

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Article

hCLOCK induction by hypoxia promotes inflammatory responses by activating the NF‑κB pathway

Xiao Tang, Daqiao Guo, Changpo Lin, Zhenyu Shi, Ruizhe Qian, Weiguo Fu, Jianjun Liu, Xu Li, Longhua Fan
Pages: 1401-1406
Published online on: 17 January 2017

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Article

TNF‑α regulates apoptosis of human vascular smooth muscle cells through gap junctions

Mei Tang, Jun Fang
Pages: 1407-1411
Published online on: 05 January 2017

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Article

Lnc‑IL7R promotes the growth of fibroblast‑like synoviocytes through interaction with enhancer of zeste homolog 2 in rheumatoid arthritis

Zhao Ye, Juan Xu, Shukui Li, Cheng Cai, Tiejun Li, Lishan Sun
Pages: 1412-1418
Published online on: 26 January 2017

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Article

Protective role of microRNA-126 in intracerebral hemorrhage

Fangen Kong, Jianhui Zhou, Wenying Zhou, Yuanqing Guo, Guowei Li, Lukun Yang
Pages: 1419-1425
Published online on: 19 January 2017

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Article

Identification of a missense mutation in the tyrosinase gene in a Chinese family with oculocutaneous albinism type 1

Qian Lu, Lamei Yuan, Hongbo Xu, Xiangjun Huang, Zhijian Yang, Junhui Yi, Bin Ni, Yong Chen, Hao Deng
Pages: 1426-1430
Published online on: 23 January 2017

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Correction Open Access

[Corrigendum] 5‑bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2‑one induces apoptosis in T24 human bladder cancer cells through mitochondria-dependent signaling pathways

Guo‑Qiang Yu, Zhong‑Ling Dou, Zhao‑Hui Jia
Pages: 1431-1431
Published online on: 27 December 2016

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Journal Cover
November-2026 Volume 34 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Research on the role and mechanism of SLC7A5 in idiopathic pulmonary fibrosis

Menghan Wang, Yao Yu, Zhaoyu Liu, Dandan Xu, Yupeng Li, Xing Zou, Ning Shan, Xining Liu, Ce Shi, Hong Chen
Article Number: 323
Published online on: 01 October 2026

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Review Open Access

Electroencephalography research in neuropathic pain (Review)

Lanling Zhou, Nianshun Liao, Hongmei Wang, Jiaxi Zhao, Haijun Jiang, Shihua Dang, Sixun Yu, Haifeng Shu, Xin Chen
Article Number: 322
Published online on: 25 September 2026

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BMAL1 in cardiovascular diseases: Molecular mechanisms, circadian regulation and translational perspectives (Review)

Yu Liang, Tingjin Chen, Xuemei Wen, Dan Liu, Zhongjian Zhang, Weiqing Li, Hengdi Zhang
Article Number: 321
Published online on: 24 September 2026

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Review Open Access

Progress on quinoline‑based antitumour agents: Mechanistic insights and optimization strategies (Review)

Yuwen Zeng, Yutong Yan, Shiye Wu, Wanshan Wu, Ke Chen, Youyi Lai, Qing Ye, Nan Zhang, Yuanyuan Zhou
Article Number: 320
Published online on: 23 September 2026

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Review Open Access

Lactylation in gastric cancer: From mechanisms to clinical applications (Review)

Yuliang Fang, Peng Chen, Yuhong Gao, Yanpiao Li, Xue Li
Article Number: 319
Published online on: 23 September 2026

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Article Open Access

Sleep deprivation exacerbates lens‑induced myopia in association with ERK/NF‑κB pathway activation

Xueli Yang, Zhou Zhang, Chengbai Zhu, Jianbo Li, Wenting Gong, Ruirui Yang, Lipeng Guan
Article Number: 318
Published online on: 22 September 2026

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Review Open Access

Advances in biomarkers of benzene exposure and toxicity: From mechanistic insights to occupational health applications (Review)

Yuanshe Huang, Zhenjun Xi, Jingxin Mao, Xiaobing Li
Article Number: 317
Published online on: 21 September 2026

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Retraction Open Access

[Retracted] CALB1 enhances the interaction between p53 and MDM2, and inhibits the senescence of ovarian cancer cells

Long-Qiao Cao, Ya-Nan Wang, Ming Liang, Mei-Zhou Pan
Article Number: 316
Published online on: 21 September 2026

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Review Open Access

Artemisinin and its derivatives for metabolic syndrome: From multi‑target mechanisms to translational opportunities (Review)

Shuo Cao, Mo Yang, Siyu Qu, Jinsong Wu, Jiaheng Li, Ying Zhao
Article Number: 315
Published online on: 17 September 2026

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Article Open Access

Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5

Fengxia Guo, Mei He, Yaonan Li, Kangning Zhu, Bing Hu
Article Number: 314
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development

Ziyue Li, Guoqing Chen, Yaling Yang, Weihua Guo, Weidong Tian
Article Number: 313
Published online on: 16 September 2026

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Review Open Access

Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Changshun Chen, Xingxi Hu, Sixing Wei, Yongcheng Deng, Qinggang Zhao, Ge Chen, Zhong Cheng, Jianhua Ji, Jinyi Gu
Article Number: 312
Published online on: 15 September 2026

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Article Open Access

Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Review Open Access

Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Review Open Access

Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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Article Open Access

High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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Article Open Access

A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Review Open Access

Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Article Open Access

Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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Retraction Open Access

[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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Article Open Access

KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Review Open Access

Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Review Open Access

Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Review Open Access

Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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December-2026 Volume 34 Issue 6

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Gut‑kidney axis in chronic kidney disease: Dysbiosis, uremic metabolites and therapeutic opportunities (Review) 

Yinding Wang, Hanyu Zeng, Na Liu, Dong Yang
Article Number: 336
Published online on: 16 October 2026

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Glycyrrhizic acid attenuates corneal inflammation and pathological angiogenesis through FAK/PI3K/AKT signaling

Jinjin Yu, Huiheng Qu, Yinming Fang, Weicheng Xu, Nannan Ding, Jie Ji, Nan Wang, Wei Shi
Article Number: 335
Published online on: 15 October 2026

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Erbin deficiency exacerbates sepsis‑induced liver injury through mitochondrial ROS/NLRP3‑mediated inflammatory responses

Jing Zuo, Xing Wang, Guoqing Jing, Xiaojing Wu, Xuemin Song
Article Number: 334
Published online on: 15 October 2026

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Review Open Access

Gut microbiota in patients receiving dialysis: Mechanisms, complications and the road to personalized microbiome‑based care (Review)

Chenxia Jin, Yanping Wang
Article Number: 333
Published online on: 15 October 2026

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Article Open Access

Epigallocatechin gallate and thermal cycling‑stimulation synergistically promote apoptosis in A549 cells via endoplasmic reticulum stress‑induced calcium ion dysregulation and oxidative stress

Fang-Tzu Hsu, Hsu-Hsiang Liu, Yi Kung, Chieh-Jou Lin, Chih-Yu Chao
Article Number: 332
Published online on: 15 October 2026

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Article Open Access

Piezo1 knockdown alleviates high‑altitude cerebral edema by improving brain microvascular endothelial cell tight junctions via blocking the calcium influx‑mediated Calpain‑1 activity

Taijian Cao, Zhicheng Xiang, Yangyang Zhao, Drolma Gomchok, Haifeng Ma, Shiwang Li, Dahai Cao, Chunqing Yang, Qiang Zhang
Article Number: 331
Published online on: 13 October 2026

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Navigating the landscape of targeted therapies for renal cell carcinoma in the era of precision medicine (Review)

Hongguo Cui, Jingheng Song, Peisen Yang, Zhengchao Zhang, Yuanyuan Liu, Gang Zhang, Aimin Tian, Jizhong Che, Yangyang Liu, Hui Sun, Yankai Xu
Article Number: 330
Published online on: 13 October 2026

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ΔNp63α‑mediated regulation of tumor‑associated genes and pathways in hepatocellular carcinoma progression

Xiaowen Lin, Anghui Peng, Min Zhang, Xinyang Yu
Article Number: 329
Published online on: 13 October 2026

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 Leptin promotes obesity‑related osteoarthritis progression via CD44/JAK2/STAT3 axis‑mediated chondrocyte apoptosis

Hao Qiu, Chao Zeng, Cheng Chen, Xin Zhou, Yongjun Zhu, Zhongliang Deng
Article Number: 328
Published online on: 09 October 2026

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Mechanical‑immune feedback regulation in distraction osteogenesis: From mechanotransduction to immune microenvironment remodeling (Review)

Xian Wang, Yuetong Wang, Shixi He, Cheng Ma, Zhengzhong He, Xuanping Huang
Article Number: 327
Published online on: 08 October 2026

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Research progress in synergistic multimechanism of nanomaterial-mediated neuroinflammatory therapy (Review)

Heng Wang, Pei Yang, Wantao Liu
Article Number: 326
Published online on: 07 October 2026

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Retraction Open Access

[Retracted] (‑)‑Epicatechin protects against myocardial ischemia‑induced cardiac injury via activation of the PTEN/PI3K/AKT pathway

Jia-Wen Li, Xiao-Yun Wang, Xin Zhang, Lei Gao, Li-Feng Wang, Xin-Hua Yin
Article Number: 325
Published online on: 05 October 2026

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Review Open Access

Lactylation and exercise: A molecular link to disease alleviation (Review)

Jian Wang, Lei Wu
Article Number: 324
Published online on: 02 October 2026

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