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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2017 Volume 15 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Chromolaena odorata: A neglected weed with a wide spectrum of pharmacological activities (Review)

Kavitha Vijayaraghavan, Johanna Rajkumar, Syed Nasir Abbas Bukhari, Badr Al‑Sayed, Mohammed Ali Seyed
Pages: 1007-1016
Published online on: 19 January 2017

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Review Open Access

Surgically‑induced mouse models in the study of bone regeneration: Current models and future directions (Review)

Bin Ning, Yunpeng Zhao, John A. Buza III, Wei Li, Wenzhao Wang, Tanghong Jia
Pages: 1017-1023
Published online on: 26 January 2017

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Article Open Access

Activity of fibroblast growth factor receptor inhibitors TKI258, ponatinib and AZD4547 against TPR‑FGFR1 fusion

Xu‑Hua Qiu, Feng Li, Hong‑Qin Cao, Jing‑Jing Shao, Jian‑Gang Mei, Han‑Qing Li, Yong‑Ping Zhai
Pages: 1024-1030
Published online on: 24 January 2017

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Article Open Access

Downregulation of microRNA‑34b is responsible for the elevation of blood pressure in spontaneously hypertensive rats

Fan Yang, Haiyu Li, Youyou Du, Qiangwei Shi, Luosha Zhao
Pages: 1031-1036
Published online on: 16 January 2017

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Article Open Access

MicroRNA-141 inhibits tumor growth and minimizes therapy resistance in colorectal cancer

Jun Ye, Zhen Wang, Jing Zhao, Wuzhen Chen, Dang Wu, Pin Wu, Jian Huang
Pages: 1037-1042
Published online on: 23 January 2017

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Article Open Access

Metabolomics study on primary dysmenorrhea patients during the luteal regression stage based on ultra performance liquid chromatography coupled with quadrupole‑time‑of‑flight mass spectrometry

Ling Fang, Caiyun Gu, Xinyu Liu, Jiabin Xie, Zhiguo Hou, Meng Tian, Jia Yin, Aizhu Li, Yubo Li
Pages: 1043-1050
Published online on: 13 January 2017

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Article Open Access

Identification of biomarkers of intrahepatic cholangiocarcinoma via integrated analysis of mRNA and miRNA microarray data

Yaqing Chen, Dan Liu, Pengfei Liu, Yajing Chen, Huiling Yu, Quan Zhang
Pages: 1051-1056
Published online on: 16 January 2017

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Article Open Access

TRIM37 promotes epithelial‑mesenchymal transition in colorectal cancer

Cheng‑En Hu, Jun Gan
Pages: 1057-1062
Published online on: 16 January 2017

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Article Open Access

Increased expression of PD‑L1 by the human papillomavirus 16 E7 oncoprotein inhibits anticancer immunity

Chaoqi Liu, Jiao Lu, Huiqun Tian, Wei Du, Lin Zhao, Jing Feng, Ding Yuan, Zhiying Li
Pages: 1063-1070
Published online on: 05 January 2017

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Article Open Access

IsomiR expression patterns in canonical and Dicer‑independent microRNAs

Tingming Liang, Jiafeng Yu, Chang Liu, Li Guo
Pages: 1071-1078
Published online on: 13 January 2017

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Article Open Access

Vitexin alleviates lipopolysaccharide‑induced islet cell injury by inhibiting HMGB1 release

Feifei Wang, Jiajing Yin, Yujin Ma, Hongwei Jiang, Yanbo Li
Pages: 1079-1086
Published online on: 12 January 2017

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Article Open Access

Integrated analysis of differentially expressed genes and pathways in triple‑negative breast cancer

Cancan Peng, Wenli Ma, Wei Xia, Wenling Zheng
Pages: 1087-1094
Published online on: 04 January 2017

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Article Open Access

Increased frequency of peripheral blood follicular helper T cells and elevated serum IL‑21 levels in patients with knee osteoarthritis

Yuxing Shan, Changlin Qi, Yijun Liu, Hui Gao, Ding Zhao, Yanfang Jiang
Pages: 1095-1102
Published online on: 19 January 2017

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Article Open Access

Interference with Tim-3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis Retraction in /10.3892/mmr.2025.13766

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Pages: 1103-1108
Published online on: 23 January 2017

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Article Open Access

Preparation and evaluation of microemulsion‑based transdermal delivery of Cistanche tubulosa phenylethanoid glycosides

Jianhua Yang, Huanhuan Xu, Shanshan Wu, Bowei Ju, Dandan Zhu, Yao Yan, Mei Wang, Junping Hu
Pages: 1109-1116
Published online on: 25 January 2017

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Article Open Access

5-ASA-loaded SiO2 nanoparticles-a novel drug delivery system targeting therapy on ulcerative colitis in mice

Haiying Tang, Dan Xiang, Feng Wang, Jingwei Mao, Xiaoyan Tan, Yingde Wang
Pages: 1117-1122
Published online on: 26 January 2017

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Article Open Access

Combination Twist1 and CA15-3 in axillary lymph nodes for breast cancer prognosis

Xiaowei Jiang, Dan Guo, Wenfang Li, Tianwu Yu, Jian Zhou, Jianping Gong
Pages: 1123-1134
Published online on: 23 January 2017

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Article Open Access

Dose‑dependent effect of lysozyme upon Candida albicans biofilm

Sarra Sebaa, Nicolas Hizette, Zahia Boucherit‑Otmani, Philippe Courtois
Pages: 1135-1142
Published online on: 25 January 2017

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Article Open Access

ATM participates in the regulation of viability and cell cycle via ellipticine in bladder cancer

Shuixiang Tao, Shuai Meng, Xiangyi Zheng, Liping Xie
Pages: 1143-1148
Published online on: 24 January 2017

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Article Open Access

Beneficial effects of sulfonamide‑based gallates on osteoblasts in vitro Corrigendum in /10.3892/mmr.2021.12152

Li Huang, Pan Jin, Xiao Lin, Cuiwu Lin, Li Zheng, Jinmin Zhao
Pages: 1149-1156
Published online on: 24 January 2017

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Article Open Access

Diagnosis for choroideremia in a large Chinese pedigree by next‑generation sequencing (NGS) and non‑invasive prenatal testing (NIPT)

Li Zhu, Jingliang Cheng, Boxu Zhou, Chunli Wei, Weichan Yang, Dong Jiang, Iqra Ijaz, Xiaojun Tan, Rui Chen, Junjiang Fu
Pages: 1157-1164
Published online on: 13 January 2017

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Article Open Access

Protective effects of physiological testosterone on advanced glycation end product‑induced injury in human endothelial cells

Yaping Xie, Dan Yu, Jiahua Wu, Lin Li
Pages: 1165-1171
Published online on: 19 January 2017

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Article Open Access

Knockdown of the differentially expressed gene TNFRSF12A inhibits hepatocellular carcinoma cell proliferation and migration in vitro

Tao Wang, Sicong Ma, Xingxing Qi, Xiaoyin Tang, Dan Cui, Zhi Wang, Jiachang Chi, Ping Li, Bo Zhai
Pages: 1172-1178
Published online on: 26 January 2017

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Article Open Access

Effect and mechanism of resveratrol on drug resistance in human bladder cancer cells

Shanshan Wang, Qian Meng, Qing Xie, Man Zhang
Pages: 1179-1187
Published online on: 12 January 2017

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Article Open Access

Resveratrol activates endogenous cardiac stem cells and improves myocardial regeneration following acute myocardial infarction

Lin Ling, Shaohua Gu, Yan Cheng
Pages: 1188-1194
Published online on: 25 January 2017

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Article Open Access

Moscatilin induces apoptosis of pancreatic cancer cells via reactive oxygen species and the JNK/SAPK pathway

Lei Zhang, Yuan Fang, Xue‑Feng Xu, Da‑Yong Jin
Pages: 1195-1203
Published online on: 25 January 2017

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Article Open Access

miR‑34c‑3p acts as a tumor suppressor gene in osteosarcoma by targeting MARCKS

Hongliang Liu, Pengxiao Su, Liqiang Zhi, Kai Zhao
Pages: 1204-1210
Published online on: 11 January 2017

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Article Open Access

MicroRNA expression signature and the therapeutic effect of the microRNA‑21 antagomir in hypertrophic scarring

Liang Guo, Kai Xu, Hongbo Yan, Haifeng Feng, Tao Wang, Linlin Chai, Guozheng Xu
Pages: 1211-1221
Published online on: 05 January 2017

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Article Open Access

Effect of ART1 on the proliferation and migration of mouse colon carcinoma CT26 cells in vivo

Jian‑Xia Xu, Wei Xiong, Zhen Zeng, Yi Tang, Ya‑Lan Wang, Ming Xiao, Ming Li, Qing Shu Li, Guang‑Lin Song, Jing Kuang
Pages: 1222-1228
Published online on: 26 January 2017

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Article Open Access

Urinary kidney injury molecule‑1 as an early diagnostic biomarker of obstructive acute kidney injury and development of a rapid detection method

Yingli Jin, Xiaona Shao, Bo Sun, Chunsheng Miao, Zhengqiang Li, Yan Shi
Pages: 1229-1235
Published online on: 05 January 2017

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Article Open Access

Proteomic analysis indicates the importance of TPM3 in esophageal squamous cell carcinoma invasion and metastasis

Shao-Bin Yu, Qin Gao, Wen-Wei Lin, Ming-Qiang Kang
Pages: 1236-1242
Published online on: 25 January 2017

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Article Open Access

Developmental expression of Toll‑like receptors in the guinea pig lung

Lingjie Ma, Jiali Yang, Li Yang, Juan Shi, Jing Xue, Yong Li, Xiaoming Liu
Pages: 1243-1251
Published online on: 17 January 2017

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Article Open Access

Systematic analysis of microarray datasets to identify Parkinson's disease‑associated pathways and genes

Yinling Feng, Xuefeng Wang
Pages: 1252-1262
Published online on: 16 January 2017

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Article Open Access

Niaspan inhibits diabetic retinopathy‑induced vascular inflammation by downregulating the tumor necrosis factor‑α pathway

Yang Wang, Xiangda Meng, Hua Yan
Pages: 1263-1271
Published online on: 25 January 2017

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Article Open Access

Protective effects of ethyl pyruvate on lipopolysaccharide‑induced acute lung injury through inhibition of autophagy in neutrophils

Qingteng Zhu, Hui Wang, Hairong Wang, Yong Luo, Yang Yu, Qirong Du, Aihua Fei, Shuming Pan
Pages: 1272-1278
Published online on: 13 January 2017

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Article Open Access

Effects of S100A6 gene silencing on the biological features of eutopic endometrial stromal cells and β‑catenin expression

Xiaoling Zhang, Zequn Liu, Meihong Chen, Qing Cao, Donghua Huang
Pages: 1279-1285
Published online on: 05 January 2017

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Article Open Access

The metastasis suppressor gene KISS-1 regulates osteosarcoma apoptosis and autophagy processes

Yiran Yin, Lian Tang, Lei Shi
Pages: 1286-1290
Published online on: 11 January 2017

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Article

Endothelial microparticles activate endothelial cells to facilitate the inflammatory response

Yiyun Liu, Ruyuan Zhang, Hongping Qu, Jun Wu, Lei Li, Yaoqing Tang
Pages: 1291-1296
Published online on: 12 January 2017

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Article

Overexpression of ILK promotes temozolomide resistance in glioma cells

Feng Liang, Bing Wang, Long Bao, Yin‑Sheng Zhao, Shi‑Min Zhang, Shu‑Qin Zhang
Pages: 1297-1304
Published online on: 26 January 2017

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Article

Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ

Xiao Zhai, Xiao Chen, Jiancan Lu, Yaping Zhang, Xuejun Sun, Qin Huang, Qijin Wang
Pages: 1305-1312
Published online on: 13 January 2017

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Article Open Access

Targeted introduction and effective expression of hFIX at the AAVS1 locus in mesenchymal stem cells

Shu‑Jun Li, Ying Luo, Le‑Meng Zhang, Wei Yang, Guo‑Gang Zhang
Pages: 1313-1318
Published online on: 19 January 2017

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Article

A novel pathway in NSCLC cells: miR‑191, targeting NFIA, is induced by chronic hypoxia, and promotes cell proliferation and migration

Jia Zhao, Cheng‑Rui Qiao, Zheng Ding, Yin‑Liang Sheng, Xiang‑Nan Li, Yang Yang, Deng‑Yan Zhu, Chun‑Yang Zhang, Dong‑Lei Liu, Kai Wu, Song Zhao
Pages: 1319-1325
Published online on: 04 January 2017

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Article Open Access

MicroRNA-410 regulates autophagy-related gene ATG16L1 expression and enhances chemosensitivity via autophagy inhibition in osteosarcoma

Ren Chen, Xiaohai Li, Bin He, Wei Hu
Pages: 1326-1334
Published online on: 26 January 2017

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Article

17β‑Estradiol treatment drives Sp1 to upregulate MALAT‑1 expression and epigenetically affects physiological processes in U2OS cells

Qiongying Hu, Shuiqin Li, Changjin Chen, Menglin Zhu, Yiming Chen, Ziyi Zhao
Pages: 1335-1342
Published online on: 12 January 2017

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Article

Homology modeling and identification of amino acids involved in the catalytic process of Mycobacterium tuberculosis serine acetyltransferase

Juanjuan Qiu, Shizhu Zang, Yufang Ma, Lawrence Owusu, Lei Zhou, Tao Jiang, Yi Xin
Pages: 1343-1347
Published online on: 26 January 2017

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Article

A clinical and molecular analysis of a patient with Emanuel syndrome

Jin‑Wen Luo, Huan Yang, Zhi‑Ping Tan, Ming Tu, Hong Luo, Yi‑Feng Yang, Li Xie
Pages: 1348-1352
Published online on: 05 January 2017

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Article

Differentiation of osteoblast‑like cells and ectopic bone formation induced by bone marrow stem cells transfected with chitosan nanoparticles containing plasmid‑BMP2 sequences

Zhang Qing Hong, Liu Meng Tao, Zhang Xiao Bin
Pages: 1353-1361
Published online on: 17 January 2017

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Article

BDNF regulates the expression and secretion of VEGF from osteoblasts via the TrkB/ERK1/2 signaling pathway during fracture healing

Zitao Zhang, Yan Zhang, Zhengnan Zhou, Hongfei Shi, Xusheng Qiu, Jin Xiong, Yixin Chen
Pages: 1362-1367
Published online on: 12 January 2017

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Article

Overexpression of GRP75 inhibits inflammation in a rat model of intracerebral hemorrhage

Lian‑Jie Lv, Jia Li, Hai‑Bo Qiao, Ben‑Jin Nie, Peng Lu, Feng Xue, Zhi‑Ming Zhang
Pages: 1368-1372
Published online on: 17 January 2017

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Article

Hypoxia-induced hsa-miR-101 promotes glycolysis by targeting TIGAR mRNA in clear cell renal cell carcinoma

Xiaochao Xu, Chao Liu, Jinku Bao
Pages: 1373-1378
Published online on: 24 January 2017

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Article

miR‑15a‑5p acts as an oncogene in renal cell carcinoma

Lu Jin, Yifan Li, Tao He, Jia Hu, Jiaju Liu, Mingwei Chen, Zeng Zhang, Yaoting Gui, Xiangming Mao, Shangqi Yang, Yongqing Lai
Pages: 1379-1386
Published online on: 16 January 2017

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Article

miRNA‑375 regulates the cell survival and apoptosis of human non‑small cell carcinoma by targeting HER2

Longqiang Cheng, Bingxiang Zhan, Peng Luo, Baolong Wang
Pages: 1387-1392
Published online on: 12 January 2017

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Article

Involvement of retinoblastoma-associated protein 48 during photodynamic therapy of cervical cancer cells

Shuxia Wu, Lijun Wang, Xingye Ren, Yulu Pan, Yan Peng, Xiaoyan Zou, Cuige Shi, Youzhong Zhang
Pages: 1393-1400
Published online on: 26 January 2017

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Article

hCLOCK induction by hypoxia promotes inflammatory responses by activating the NF‑κB pathway

Xiao Tang, Daqiao Guo, Changpo Lin, Zhenyu Shi, Ruizhe Qian, Weiguo Fu, Jianjun Liu, Xu Li, Longhua Fan
Pages: 1401-1406
Published online on: 17 January 2017

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Article

TNF‑α regulates apoptosis of human vascular smooth muscle cells through gap junctions

Mei Tang, Jun Fang
Pages: 1407-1411
Published online on: 05 January 2017

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Article

Lnc‑IL7R promotes the growth of fibroblast‑like synoviocytes through interaction with enhancer of zeste homolog 2 in rheumatoid arthritis

Zhao Ye, Juan Xu, Shukui Li, Cheng Cai, Tiejun Li, Lishan Sun
Pages: 1412-1418
Published online on: 26 January 2017

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Article

Protective role of microRNA-126 in intracerebral hemorrhage

Fangen Kong, Jianhui Zhou, Wenying Zhou, Yuanqing Guo, Guowei Li, Lukun Yang
Pages: 1419-1425
Published online on: 19 January 2017

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Article

Identification of a missense mutation in the tyrosinase gene in a Chinese family with oculocutaneous albinism type 1

Qian Lu, Lamei Yuan, Hongbo Xu, Xiangjun Huang, Zhijian Yang, Junhui Yi, Bin Ni, Yong Chen, Hao Deng
Pages: 1426-1430
Published online on: 23 January 2017

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Correction Open Access

[Corrigendum] 5‑bromo-3-(3-hydroxyprop-1-ynyl)-2H-pyran-2‑one induces apoptosis in T24 human bladder cancer cells through mitochondria-dependent signaling pathways

Guo‑Qiang Yu, Zhong‑Ling Dou, Zhao‑Hui Jia
Pages: 1431-1431
Published online on: 27 December 2016

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Journal Cover
January-2026 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Article Open Access

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Review Open Access

Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Article Open Access

Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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