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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2012 Volume 6 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

BRAF mutations in papillary thyroid carcinoma and emerging targeted therapies (Review)

Giulia Costanza Leonardi, Saverio Candido, Maurizio Carbone, Fabio Raiti, Valeria Colaianni, Sebastiano Garozzo, Diana Cinà, James A. McCubrey, Massimo Libra
Pages: 687-694
Published online on: 02 August 2012

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Review

Role of microRNAs in peripheral artery disease (Review)

Xiangyu Zhou, Ping Yuan, Yanzheng He
Pages: 695-700
Published online on: 05 July 2012

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Article

Cell cycle regulation by bevacizumab in ARPE-19 human retinal pigment epithelial cells

Chien-Neng Kuo, Chung-Yi Chen, Chien-Hsiung Lai, Li-Ju Lai, Pei-Chen Wu, Chia-Hui Hung, Ching-Hsein Chen
Pages: 701-704
Published online on: 11 July 2012

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Article

MRP3 gene expression correlates with NRF2 mutations in lung squamous cell carcinomas

Hidefumi Sasaki, Masayuki Shitara, Keisuke Yokota, Yu Hikosaka, Satoru Moriyama, Motoki Yano, Yoshitaka Fujii
Pages: 705-708
Published online on: 05 July 2012

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Article

Effects of dimethylolpropionic acid modification on the characteristics of polyethylene terephthalate fibers

Zhaosong Huang, Long Bi, Zhenyu Zhang, Yisheng Han
Pages: 709-715
Published online on: 30 July 2012

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Article

Expression of NGAL and NGALR in human embryonic, fetal and normal adult tissues

Pi-Xian Zhang, Fa-Ren Zhang, Jian-Jun Xie, Li-Hua Tao, Zhuo Lü, Xiu-E Xu, Jian Shen, Li-Yan Xu, En-Min Li
Pages: 716-722
Published online on: 06 July 2012

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Article

Potential role of metalloproteinase inhibitors from radiation‑sterilized amnion dressings in the healing of venous leg ulcers

Małgorzata Litwiniuk, Barbara Bikowska, Justyna Niderla-Bielińska, Jarosław Jóźwiak, Artur Kamiński, Piotr Skopiński, Tomasz Grzela
Pages: 723-728
Published online on: 11 July 2012

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Article

Heat shock protein 70 induced by heat stress protects heterotopically transplanted hearts in rats

Li-Wei Diao, Lin-Lin Zhao, Feng Qi, Zhen-Dong Sun, Qing-Hua Zhang, Nai-Shi Wu
Pages: 729-732
Published online on: 09 July 2012

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Article

Expression of hBD-2 induced by 23-valent pneumococcal polysaccharide vaccine, Haemophilus influenzae type b vaccine and split influenza virus vaccine

Zhenwei Shen, Han Lei
Pages: 733-738
Published online on: 26 July 2012

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Article

Protective effects of glutamine in a rat model of endotoxemia

Ya-Juan Zhao, Hong Wang, Xin Liu, Mei Sun, Haginoya Kazuhiro
Pages: 739-744
Published online on: 26 July 2012

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Article

Differentiation of bone marrow-derived mesenchymal stem cells into chondrocytes using chondrocyte extract

Xinjie Tang, Lingling Sheng, Feng Xie, Qun Zhang
Pages: 745-749
Published online on: 19 July 2012

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Article

Suppression of c-jun influences nNOS expression in differentiated PC12 cells

Xiao Cheng, Shu Liu, Ya-Qiong Wang, Ying-Qin Li, Rao Fu, Ying Tang, Wen-Hua Zheng, Li-Hua Zhou
Pages: 750-754
Published online on: 12 July 2012

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Article

Investigation of myoepithelial cell differentiation into Schwann-like cells in salivary adenoid cystic carcinoma associated with perineural invasion

Wei Chen, Shaozhong Dong, Jun Zhou, Moyi Sun
Pages: 755-759
Published online on: 24 July 2012

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Article

Characterization of placenta-derived mesenchymal stem cells cultured in autologous human cord blood serum

Libin Wang, Yinxue Yang, Yongzhao Zhu, Xiaona Ma, Ting Liu, Guangyi Zhang, Heng Fan, Lijun Ma, Yiran Jin, Xiurui Yan, Jun Wei, Yukui Li
Pages: 760-766
Published online on: 23 July 2012

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Article

Role of heat shock protein 27 in gemcitabine-resistant human pancreatic cancer: Comparative proteomic analyses

Qing-Hua Liu, Chen-Yan Zhao, Jing Zhang, Ying Chen, Li Gao, Can-Yong Ni, Ming-Hua Zhu
Pages: 767-773
Published online on: 31 July 2012

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Article

Lipopolysaccharide regulates MMP-9 expression through TLR4/NF-κB signaling in human arterial smooth muscle cells

Hongli Li, Hao Xu, Baogui Sun
Pages: 774-778
Published online on: 27 July 2012

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Article

Pathological features and prognosis of different molecular subtypes of breast cancer

Guo-Sheng Wang, Hong Zhu, Shi-Jie Bi
Pages: 779-782
Published online on: 09 July 2012

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Article

A method for the establishment of a cell line with stable expression of the GFP-LC3 reporter protein

Dong Hu, Jing Wu, Lifa Xu, Rongbo Zhang, Liping Chen
Pages: 783-786
Published online on: 16 July 2012

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Article

FK506-binding protein 51 (FKBP5) gene polymorphism is not associated with glucocorticoid therapy outcome in patients with idiopathic thrombocytopenic purpura

Wansheng Lao, Meiyun Fang, Xifei Yang
Pages: 787-790
Published online on: 18 July 2012

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Article

Analgesic and anti-inflammatory effects in animal models of an ethanolic extract of Taheebo, the inner bark of Tabebuia avellanedae

Mu Hong Lee, Hyun Mi Choi, Dae-Hyun Hahm, Erk Her, Hyung-In Yang, Myung Chul Yoo, Kyoung Soo Kim
Pages: 791-796
Published online on: 17 July 2012

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Article

Association between manganese superoxide dismutase gene polymorphism and breast cancer risk: A meta-analysis of 17,842 subjects

Geling Liu, Guogui Sun, Yadi Wang, Dan Wang, Wanning Hu, Jun Zhang
Pages: 797-804
Published online on: 20 July 2012

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Article

Involvement of phospholipase C-γ in the pro-survival role of glial cell line-derived neurotrophic factor in developing motoneurons in rat spinal cords

Rao Fu, Li-Qing Wang, Guo-Liang Chu, Li-Hua Zhou
Pages: 805-810
Published online on: 17 July 2012

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Article

Changes in the expression of cardiac mitofusin-2 in different stages of diabetes in rats

Qin Gao, Xiao-Mei Wang, Hong-Wei Ye, Ying Yu, Pin-Fang Kang, Hong-Ju Wang, Su-Dong Guan, Zheng-Hong Li
Pages: 811-814
Published online on: 23 July 2012

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Article

Polydatin alleviates non-alcoholic fatty liver disease in rats by inhibiting the expression of TNF-α and SREBP-1c

Jingming Zhang, Yingying Tan, Fanrong Yao, Qi Zhang
Pages: 815-820
Published online on: 31 July 2012

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Article

microrna expression signature of gastric cancer cells relative to normal gastric mucosa

Bei-Qin Yu, Li-Ping Su, Jian-Fang Li, Qu Cai, Min Yan, Xue-Hua Chen, Ying-Yan Yu, Qin-Long Gu, Zheng-Gang Zhu, Bing-Ya Liu
Pages: 821-826
Published online on: 26 July 2012

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Article

Lead acetate reduces the ability of human umbilical cord mesenchymal stem cells to support hematopoiesis in vitro

Xiaochun Sun, Yan Xie, Lele Wu, Wei Zhu, Jiabo Hu, Rongzhu Lu, Wenrong Xu
Pages: 827-832
Published online on: 31 July 2012

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Article

Deoxycholic acid inhibits smooth muscle contraction via protein kinase C-dependent modulation of L-type Ca2+ channels in rat proximal colon

Liu-Dan Hu, Bao-Ping Yu, Bin Yang
Pages: 833-837
Published online on: 11 July 2012

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Article

Hypoferraemia during the early inflammatory response is dependent on tumour necrosis factor activity in a murine model of protracted peritonitis

Thomas E.O. Schubert, Anja K. Bosserhoff, Carole Peyssonaux, Bernd  Echtenacher, Mitchell Knutson, Ferdinand Hofstädter, Daniela N. Männel
Pages: 838-842
Published online on: 24 July 2012

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Article

Althaea rosea Cavanil and Plantago major L. suppress neoplastic cell transformation through the inhibition of epidermal growth factor receptor kinase

Eun-Sun Choi, Sung-Dae Cho, Ji-Ae Shin, Ki Han Kwon, Nam-Pyo Cho, Jung-Hyun Shim
Pages: 843-847
Published online on: 04 July 2012

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Article

Therapeutic effect of mesenchymal stem cells in rats with intracerebral hemorrhage: Reduced apoptosis and enhanced neuroprotection

Su-Ping Wang, Zi-Han Wang, Dao-Yong Peng, Shu-Min Li, Hong Wang, Xiao-Hong Wang
Pages: 848-854
Published online on: 20 July 2012

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Article

Changes in ADMA and TAFI levels after stenting in coronary artery disease patients

Nouran M. Khalifa, Mohamed Z. Gad, Alaa A. Hataba, Laila G. Mahran
Pages: 855-859
Published online on: 11 July 2012

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Article

Effects of curcumin on bleomycin‑induced oxidative stress in malignant testicular germ cell tumors

Aysegul Cort, Evrim Ozdemir, Mujgan Timur, Tomris Ozben
Pages: 860-866
Published online on: 17 July 2012

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Article

Activity and tumor specificity of human heparanase gene core promoter

Xiao-Peng Chen, Liang-He Hu, Wei Cui, Dong Wang, Ming‑Shi Wu, Jun-Sheng Luo, Min Zhong
Pages: 867-871
Published online on: 17 July 2012

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Article

Trichosanthin inhibits DNA methyltransferase and restores methylation-silenced gene expression in human cervical cancer cells

Yiling Huang, Huamei Song, Huojun Hu, Lei Cui, Chengcheng You, Liming Huang
Pages: 872-878
Published online on: 18 July 2012

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Article

Correlation between LRRK2 gene G2385R polymorphisms and Parkinson's disease

Huiru Yan, Qingping Ma, Xinling Yang, Yuling Wang, Yani Yao, Hongjuan Li
Pages: 879-883
Published online on: 26 July 2012

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Article

Angiotensinogen gene M235T polymorphism and risk of coronary artery disease: A meta-analysis

Yu-Jing Wang, Yan Pan
Pages: 884-888
Published online on: 27 July 2012

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Article

Correlations between cognitive impairment and brain‑derived neurotrophic factor expression in the hippocampus of post-stroke depression rats

Zhao-Hui Zhang, Li-Na Wu, Jing-Gui Song, Wen-Qiang Li
Pages: 889-893
Published online on: 26 July 2012

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Article

The A to G polymorphism at -1082 of the interleukin-10 gene is rare in the Han Chinese population

Jing Guo, Yong-Hui He, Feng Chen, Min-Hui Jiang, Shu-Ping Gao, Ya‑Ming  Su, Gui-Liang Shi, Xin-Tao Deng, Jian-Hua Zhu, Min Pan
Pages: 894-896
Published online on: 18 July 2012

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Article

The Chk1 inhibitor AZD7762 sensitises p53 mutant breast cancer cells to radiation in vitro and in vivo

Zhikun Ma, Guoliang Yao, Bo Zhou, Yonggang Fan, Shegan Gao, Xiaoshan Feng
Pages: 897-903
Published online on: 20 July 2012

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Article

p16 promoter hypermethylation is associated with increased breast cancer risk

Li Wang, Lin Tang, Ruilian Xie, Weiwei Nie, Longbang Chen, Xiaoxiang Guan
Pages: 904-908
Published online on: 23 July 2012

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

CTRP4 ameliorates dexamethasone‑induced insulin resistance through the IRS‑1/PI3K/AKT pathway in 3T3‑L1 adipocytes

Maireyanmu Rouzi, Xi Sun, Luguang Sheng, Bilin Xu, Tao Lei, Jun Lu, Jie Gao
Article Number: 101
Published online on: 27 January 2026

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Article Open Access

PTUPB, a soluble epoxide hydrolase/cyclooxygenase‑2 dual inhibitor, reduces endothelial‑to‑mesenchymal transition and improves doxorubicin‑induced vascular and cardiac toxicity

Hevna Dhulkifle, Lubna Therachiyil, Maram H. Hasan, Shahd M. Younis, Nizar A. Al‑Shar'i, Huseyin C. Yalcin, Zaid H. Maayah
Article Number: 100
Published online on: 27 January 2026

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Retraction Open Access

[Retracted] miR‑367 enhances the proliferation and invasion of cutaneous malignant melanoma by regulating phosphatase and tensin homolog expression

Jianwen Long, Jing Luo, Xuwen Yin
Article Number: 99
Published online on: 26 January 2026

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Review Open Access

Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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Article Open Access

HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Article Open Access

Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Review Open Access

Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Review Open Access

Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Article Open Access

Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Article Open Access

Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Review Open Access

Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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April-2026 Volume 33 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Research status and molecular mechanisms of disulfidptosis in cardiovascular diseases (Review)

Xiao Jin, Zelin Cheng, Xinyue Ding, Zongjun Liu
Article Number: 106
Published online on: 03 February 2026

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Article Open Access

Role and mechanism of tetrahedral DNA nanostructures in the repair of urethral injury in rats

Caifen Guo, Jian Li
Article Number: 105
Published online on: 02 February 2026

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Retraction Open Access

[Retracted] MicroRNA‑4500 suppresses tumor progression in non‑small cell lung cancer by regulating STAT3

Zhi-Ying Li, Zi-Zhou Zhang, Hui Bi, Qiu-Di Zhang, Su-Juan Zhang, Lin Zhou, Xiao-Qin Zhu, Jun Zhou
Article Number: 104
Published online on: 02 February 2026

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Article Open Access

Integrative bioinformatics and experimental analysis reveals FRA1 as a key mediator of tubulointerstitial inflammation in lupus nephritis

Wenpeng Ni, Jialin He, Zhouyu Zeng, Jialong Ke, Runpei Lin, Jianming Peng, Kunyi Deng, Lijuan Wen, Yanhui Chen, Chilun Zhang, Yanfen Li, Guanghong Gu
Article Number: 103
Published online on: 28 January 2026

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Correction Open Access

[Corrigendum] Resveratrol improves neurological outcome and neuroinflammation following spinal cord injury through enhancing autophagy involving the AMPK/mTOR pathway

Hong-Yu Meng, De-Cheng Shao, Han Li, Xiao-Dan Huang, Guang Yang, Bing Xu, Hai-Yun Niu
Article Number: 102
Published online on: 28 January 2026

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