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International Journal of Molecular Medicine
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2016 Volume 37 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Molecular mechanisms of cell death in intervertebral disc degeneration (Review)

Fan Zhang, Xueling Zhao, Hongxing Shen, Caiguo Zhang
Pages: 1439-1448
Published online on: 21 April 2016

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An examination of the regulatory mechanism of Pxdn mutation-induced eye disorders using microarray analysis

Yang Yang, Yiqiao Xing, Chaoqun Liang, Liya Hu, Fei Xu, Qi Mei
Pages: 1449-1456
Published online on: 20 April 2016

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Anti-inflammatory effects of novel AP-1 and NF-κB inhibitors in dextran-sulfate-sodium-induced colitis in rats

Magdy El-Salhy, Kazuo Umezawa
Pages: 1457-1464
Published online on: 12 April 2016

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Effect of CD16a, the surface receptor of Kupffer cells, on the growth of hepatocellular carcinoma cells

Xiu-Yun Li, Lun Wu, Sheng-Wei Li, Wen-Bo Zhou, Meng-Yuan Wang, Guo-Qing Zuo, Chang-An Liu, Xiong Ding
Pages: 1465-1474
Published online on: 12 April 2016

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Article Open Access

Estrogen enhances the bone regeneration potential of periodontal ligament stem cells derived from osteoporotic rats and seeded on nano-hydroxyapatite/collagen/poly(L-lactide)

Ling-Ling E, Wen-Huan Xu, Lin Feng, Yi Liu, Dong-Qing Cai, Ning Wen, Wen-Jie Zheng
Pages: 1475-1486
Published online on: 12 April 2016

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Article Open Access

Analysis of SLC4A11, ZEB1, LOXHD1, COL8A2 and TCF4 gene sequences in a multi-generational family with late-onset Fuchs corneal dystrophy

Hui Tang, Wen Zhang, Xin-Min Yan, Lin-Ping Wang, Hong Dong, Tao Shou, Huo Lei, Qiang Guo
Pages: 1487-1500
Published online on: 20 April 2016

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Article Open Access

Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-β-boswellic acid in combination on isoproterenol-induced myocardial injury in rats Corrigendum in /10.3892/ijmm.2021.5067

Minchun Chen, Mingming Wang, Qiong Yang, Min Wang, Zhipeng Wang, Yanrong Zhu, Yikai Zhang, Chao Wang, Yanyan Jia, Yuwen Li, Aidong Wen
Pages: 1501-1510
Published online on: 20 April 2016

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Article Open Access

Identification of novel mutations including a double mutation in patients with inherited cardiomyopathy by a targeted sequencing approach using the Ion Torrent PGM system

Yue Zhao, Hong Cao, Yindi Song, Yue Feng, Xiaoxue Ding, Mingjie Pang, Yunmei Zhang, Hong Zhang, Jiahuan Ding, Xueshan Xia
Pages: 1511-1520
Published online on: 14 April 2016

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Article Open Access

293 cells express both epithelial as well as mesenchymal cell adhesion molecules

Masakazu Inada, Genya Izawa, Wakako Kobayashi, Masayuki Ozawa
Pages: 1521-1527
Published online on: 18 April 2016

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Article Open Access

Whole-exome sequencing identifies a novel homozygous frameshift mutation in the PROM1 gene as a causative mutation in two patients with sporadic retinitis pigmentosa

Sanmei Liu, Lan Xie, Jun Yue, Tao Ma, Chunyan Peng, Biyuan Qiu, Zhenglin Yang, Jiyun Yang
Pages: 1528-1534
Published online on: 08 April 2016

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Article Open Access

Tumor-associated fibroblasts promote the proliferation and decrease the doxorubicin sensitivity of liposarcoma cells

Kamran Harati, Adrien Daigeler, Tobias Hirsch, Frank Jacobsen, Björn Behr, Christoph Wallner, Marcus Lehnhardt, Mustafa Becerikli
Pages: 1535-1541
Published online on: 11 April 2016

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Docosahexenoic acid treatment ameliorates cartilage degeneration via a p38 MAPK-dependent mechanism

Zhenzhong Wang, Ai Guo, Lifeng Ma, Haomiao Yu, Liang Zhang, Hai Meng, Yinpeng Cui, Fei Yu, Bo Yang
Pages: 1542-1550
Published online on: 14 April 2016

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High expression of DDX20 enhances the proliferation and metastatic potential of prostate cancer cells through the NF-κB pathway

Weiguo Chen, Peng Zhou, Xiaowei Li
Pages: 1551-1557
Published online on: 25 April 2016

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Sitagliptin inhibits endothelin-1 expression in the aortic endothelium of rats with streptozotocin-induced diabetes by suppressing the nuclear factor-κB/IκBα system through the activation of AMP-activated protein kinase

Song-Tao Tang, Huan Su, Qiu Zhang, Hai-Qin Tang, Chang-Jiang Wang, Qing Zhou, Wei Wei, Hua-Qing Zhu, Yuan Wang
Pages: 1558-1566
Published online on: 26 April 2016

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Artemisinin inhibits monocyte adhesion to HUVECs through the NF-κB and MAPK pathways in vitro

Yue Wang, Jiatian Cao, Yuqi Fan, Yushui Xie, Zuojun Xu, Zhaofang Yin, Lin Gao, Changqian Wang
Pages: 1567-1575
Published online on: 26 April 2016

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Construction and analysis of protein-protein interaction networks based on proteomics data of prostate cancer

Chen Chen, Hong Shen, Li-Guo Zhang, Jian Liu, Xiao-Ge Cao, An-Liang Yao, Shao-San Kang, Wei-Xing Gao, Hui Han, Feng-Hong Cao, Zhi-Guo Li
Pages: 1576-1586
Published online on: 26 April 2016

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Article Open Access

MicroRNA-130b promotes cell proliferation and invasion by inhibiting peroxisome proliferator-activated receptor-γ in human glioma cells

Jian-Jun Gu, Jian-He Zhang, Hong-Jie Chen, Shou-Sen Wang
Pages: 1587-1593
Published online on: 27 April 2016

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Article

Clinical implications of the growth-suppressive effects of chlorhexidine at low and high concentrations on human gingival fibroblasts and changes in morphology

Marzena Wyganowska-Swiatkowska, Malgorzata Kotwicka, Paulina Urbaniak, Agnieszka Nowak, Ewa Skrzypczak-Jankun, Jerzy Jankun
Pages: 1594-1600
Published online on: 07 April 2016

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Article

Suppression of SIK1 by miR-141 in human ovarian cancer cell lines and tissues Expression of Concern in /10.3892/ijmm.2025.5627 Retraction in /10.3892/ijmm.2025.5700

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Pages: 1601-1610
Published online on: 11 April 2016

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Article

Mitochondrial ubiquitin ligase activator of NF-κB regulates NF-κB signaling in cells subjected to ER stress

Hidetoshi Fujita, Satoko Aratani, Ryouji Fujii, Yoshihisa Yamano, Naoko Yagishita, Natsumi Araya, Toshihiko Izumi, Kazuko Azakami, Daisuke Hasegawa, Kusuki Nishioka, Toshihiro Nakajima
Pages: 1611-1618
Published online on: 14 April 2016

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Article

A potential role for zinc transporter 7 in testosterone synthesis in mouse Leydig tumor cells

Qingqing Chu, Zhi-Hong Chi, Xiuli Zhang, Dan Liang, Xuemei Wang, Yue Zhao, Li Zhang, Ping Zhang
Pages: 1619-1626
Published online on: 25 April 2016

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Article

miR-143 inhibits oncogenic traits by degrading NUAK2 in glioblastoma

Ting-Gang Fu, Ling Wang, Wei Li, Jian-Zhong Li, Jian Li
Pages: 1627-1635
Published online on: 13 April 2016

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Article

miR-133a enhances the sensitivity of Hep-2 cells and vincristine-resistant Hep-2v cells to cisplatin by downregulating ATP7B expression

Xurui Wang, Wei Zhu, Xiaodong Zhao, Ping Wang
Pages: 1636-1642
Published online on: 20 April 2016

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Article

MicroRNA-101 inhibits cell proliferation and induces apoptosis by targeting EYA1 in breast cancer

Haitao Guan, Zhijun Dai, Yuguang Ma, Zhongwei Wang, Xiaoxu Liu, Xijing Wang
Pages: 1643-1651
Published online on: 11 April 2016

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Article

Polydatin inhibits the oxidative stress-induced proliferation of vascular smooth muscle cells by activating the eNOS/SIRT1 pathway

Yi Ma, Xun Gong, Yingli Mo, Saizhu Wu
Pages: 1652-1660
Published online on: 11 April 2016

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Article

Hydrogen sulfide protects H9c2 cardiac cells against doxorubicin-induced cytotoxicity through the PI3K/Akt/FoxO3a pathway

Mi-Hua Liu, Yuan Zhang, Jun He, Tian-Ping Tan, Shao-Jian Wu, Dong-Ming Guo, Hui He, Juan Peng, Zhi-Han Tang, Zhi-Sheng Jiang
Pages: 1661-1668
Published online on: 14 April 2016

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Article

Plumbagin exerts protective effects in nucleus pulposus cells by attenuating hydrogen peroxide-induced oxidative stress, inflammation and apoptosis through NF-κB and Nrf-2

Hui Chu, Hang Yu, Ding Ren, Kejun Zhu, Hong Huang
Pages: 1669-1676
Published online on: 14 April 2016

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Article

Downregulation of microRNA-429 protects cardiomyocytes against hypoxia-induced apoptosis by increasing Notch1 expression

Han Xu, Long Jin, Yan Chen, Junzhi Li
Pages: 1677-1685
Published online on: 12 April 2016

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Article

Valproic acid enhances the antileukemic effect of cytarabine by triggering cell apoptosis

Nan Liu, Chen Wang, Libing Wang, Lei Gao, Hui Cheng, Gusheng Tang, Xiaoxia Hu, Jianmin Wang
Pages: 1686-1696
Published online on: 08 April 2016

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Article

Astragaloside IV facilitates glucose transport in C2C12 myotubes through the IRS1/AKT pathway and suppresses the palmitate-induced activation of the IKK/IκBα pathway

Rongfeng Zhu, Jianjun Zheng, Lizhen Chen, Bin Gu, Shengli Huang
Pages: 1697-1705
Published online on: 11 April 2016

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Article

Effects of nitrogen on the apoptosis of and changes in gene expression in human lymphoma U937 cells exposed to argon-based cold atmospheric pressure plasma

Yoshiaki Tabuchi, Hidefumi Uchiyama, Qing-Li Zhao, Tatsuya Yunoki, Gabor Andocs, Nobuyuki Nojima, Keigo Takeda, Kenji Ishikawa, Masaru Hori, Takashi Kondo
Pages: 1706-1714
Published online on: 25 April 2016

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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