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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2015 Volume 46 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Nanoparticle strategies for cancer therapeutics: Nucleic acids, polyamines, bovine serum amine oxidase and iron oxide nanoparticles (Review)

Enzo Agostinelli, Fabio Vianello, Giuseppe Magliulo, Thresia Thomas, T. J. Thomas
Pages: 5-16
Published online on: 14 October 2014

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Review

The fusion of two worlds: Non-coding RNAs and extracellular vesicles - diagnostic and therapeutic implications (Review)

Yukie Sato-Kuwabara, Sonia A. Melo, Fernando A. Soares, George A. Calin
Pages: 17-27
Published online on: 17 October 2014

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Article Open Access

Programmed death-1 blockade enhances the antitumor effects of peptide vaccine-induced peptide-specific cytotoxic T lymphocytes

Yu Sawada, Toshiaki Yoshikawa, Manami Shimomura, Tatsuaki Iwama, Itaru Endo, Tetsuya Nakatsura
Pages: 28-36
Published online on: 30 October 2014

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Article Open Access

Conditioned media from human macrophages of M1 phenotype attenuate the cytotoxic effect of 5‑fluorouracil on the HT‑29 colon cancer cell line

Alexander Hedbrant, Ann Erlandsson, Dick Delbro, Jonny Wijkander
Pages: 37-46
Published online on: 07 October 2014

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Article Open Access

Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells

Masaki Mori, Toshiaki Hitora, Osamu Nakamura, Yoshiki Yamagami, Ryosuke Horie, Hideki Nishimura, Tetsuji Yamamoto
Pages: 47-54
Published online on: 23 October 2014

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Article

Feasibility study of personalized peptide vaccination for advanced non-small cell lung cancer patients who failed two or more treatment regimens

Teppei Yamada, Yasuhiro Terazaki, Shinjiro Sakamoto, Koichi Yoshiyama, Satoko Matsueda, Nobukazu Komatsu, Kayoko Waki, Akira Yamada, Akihiko Kawahara, Masayoshi Kage, Shunichi Sugawara, Yuichi Yamashita, Tetsuro Sasada, Shinzo Takamori, Kyogo Itoh
Pages: 55-62
Published online on: 07 October 2014

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Article

5-FU resistance abrogates the amplified cytotoxic effects induced by inhibiting checkpoint kinase 1 in p53-mutated colon cancer cells

Tomofumi Akasaka, Masahiko Tsujii, Jumpei Kondo, Yoshito Hayashi, Jin  Ying, Yuquan  Lu, Motohiko Kato, Takuya Yamada, Shunsuke  Yamamoto, Takuya Inoue, Yoshiki Tsujii, Akira Maekawa, Tetsuji Fujinaga, Eri  Shiraishi, Satoshi Hiyama, Takahiro Inoue, Shinichiro Shinzaki, Kenji  Watabe, Tsutomu  Nishida, Hideki Iijima, Tetsuo Takehara
Pages: 63-70
Published online on: 06 October 2014

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Article

Strong T‑cell costimulation can reactivate tumor antigen‑specific T cells in late‑stage metastasized colorectal carcinoma patients: Results from a phase Ⅰ clinical study

Volker Schirrmacher, Christoph Schlude, Jürgen Weitz, Philipp Beckhove
Pages: 71-77
Published online on: 06 October 2014

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Article

Pancreatic cancer immunotherapy using a tumor lysate vaccine, engineered to express α-gal epitopes, targets pancreatic cancer stem cells

Tsukasa Tanida, Masahiro Tanemura, Eiji Miyoshi, Hiroaki Nagano, Kenta Furukawa, Yuji Nonaka, Hirofumi Akita, Naoki Hama, Hiroshi Wada, Koichi Kawamoto, Shogo Kobayashi, Hidetoshi Eguchi, Masaki Mori, Yuichiro Doki
Pages: 78-90
Published online on: 21 October 2014

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Article

Transformation of NIH3T3 mouse fibroblast cells by MUC16 mucin (CA125) is driven by its cytoplasmic tail

Panagiota Giannakouros, Isabelle Matte, Claudine Rancourt, Alain Piché
Pages: 91-98
Published online on: 14 October 2014

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Article

Autoacetylation regulates differentially the roles of ARD1 variants in tumorigenesis

Ji Hae Seo, Ji-Hyeon Park, Eun Ji Lee, Tam Thuy Lu Vo, Hoon Choi, Jae Kyung Jang, Hee-Jun Wee, Bum Ju Ahn, Jong-Ho Cha, Min Wook Shin, Kyu-Won Kim
Pages: 99-106
Published online on: 17 October 2014

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Article

Expression pattern of the PRDX2, RAB1A, RAB1B, RAB5A and RAB25 genes in normal and cancer cervical tissues

Andrej Nikoshkov, Kristina Broliden, Sanaz Attarha, Vitali Sviatoha, Ann‑Cathrin Hellström, Miriam Mints, Sonia Andersson
Pages: 107-112
Published online on: 23 October 2014

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Article

Downregulation of thymidylate synthase and E2F1 by arsenic trioxide in mesothelioma

Sze-Kwan Lam, Yuan-Yuan Li, Chun-Yan Zheng, James Chung-Man Ho
Pages: 113-122
Published online on: 21 October 2014

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Article

Prognostic significance of SOX18 expression in non-small cell lung cancer

Aleksandra Jethon, Bartosz Pula, Mateusz Olbromski, Bozena Werynska, Beata Muszczynska-Bernhard, Wojciech Witkiewicz, Piotr Dziegiel, Marzena Podhorska-Okolow
Pages: 123-132
Published online on: 07 October 2014

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Article

+TIP EB1 downregulates paclitaxel‑induced proliferation inhibition and apoptosis in breast cancer cells through inhibition of paclitaxel binding on microtubules

Geethu Emily Thomas, Jamuna S. Sreeja, K. K. Gireesh, Hindol Gupta, Tapas K. Manna
Pages: 133-146
Published online on: 07 October 2014

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Article

Potent tumor tropism of induced pluripotent stem cells and induced pluripotent stem cell-derived neural stem cells in the mouse intracerebral glioma model

Tomohiro Yamazoe, Shinichiro Koizumi, Tomohiro Yamasaki, Shinji Amano, Tsutomu Tokuyama, Hiroki Namba
Pages: 147-152
Published online on: 08 October 2014

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Article

Mutation of β-catenin in a radiation and estrogen breast cancer model

Debasish Roy, Gloria M. Calaf
Pages: 153-160
Published online on: 22 October 2014

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Article

MicroRNA-93 regulates cyclin G2 expression and plays an oncogenic role in laryngeal squamous cell carcinoma

Xiyan Xiao, Liang Zhou, Pengyu Cao, Hongli Gong, Yanping Zhang
Pages: 161-174
Published online on: 10 October 2014

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Article

Prognostic significance and therapeutic implications of peroxisome proliferator-activated receptor γ overexpression in human pancreatic carcinoma

Yan Zhang, Hui-Yan Luo, Guang-Lin Liu, De-Shen Wang, Zhi-Qiang Wang, Zhao-Lei Zeng, Rui-Hua Xu
Pages: 175-184
Published online on: 17 October 2014

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Article

Silencing of galectin-3 represses osteosarcoma cell migration and invasion through inhibition of FAK/Src/Lyn activation and β-catenin expression and increases susceptibility to chemotherapeutic agents

Ga Bin Park, Dae-Jin Kim, Yeong-Seok Kim, Hyun-Kyung Lee, Chang Wan Kim, Dae Young Hur
Pages: 185-194
Published online on: 22 October 2014

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Article

The Pleckstrin and Sec7 domain-containing gene as a novel epigenetic modification marker in human gastric cancer and its clinical significance Corrigendum in /10.3892/ijo.2022.5313

Xinjiang Zhu, Jian Liu, Xiaoyang Xu, Chundong Zhang, Dongqiu Dai
Pages: 195-204
Published online on: 30 October 2014

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Article

Eps8 regulates cellular proliferation and migration of breast cancer

Cheng Chen, Zhongheng Liang, Wenhuan Huang, Xinxin Li, Fangliang Zhou, Xiang Hu, Mei Han, Xiaofeng Ding, Shuanglin Xiang
Pages: 205-214
Published online on: 17 October 2014

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Article

HIF-1α decoy oligodeoxynucleotides inhibit HIF-1α signaling and breast cancer proliferation

Xuhong Zhu, Qin Li, Shuang Li, Bote Chen, Haidong Zou
Pages: 215-222
Published online on: 21 October 2014

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Article

PJ34, a poly(ADP-ribose) polymerase (PARP) inhibitor, reverses melphalan-resistance and inhibits repair of DNA double-strand breaks by targeting the FA/BRCA pathway in multidrug resistant multiple myeloma cell line RPMI8226/R

Ting Xiong, Heng Wei, Xiaoqiong Chen, Hui Xiao
Pages: 223-232
Published online on: 23 October 2014

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Article

HIF2α is associated with poor prognosis and affects the expression levels of survivin and cyclin D1 in gastric carcinoma

Wei-Wei Tong, Guang-Hui Tong, Xie-Xiao Chen, Hua-Chuan Zheng, Yin-Zhao Wang
Pages: 233-242
Published online on: 22 October 2014

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Article

Oxime bond-linked daunorubicin-GnRH-III bioconjugates exert antitumor activity in castration-resistant prostate cancer cells via the type I GnRH receptor

Marina Montagnani Marelli, Marilena Manea, Roberta M. Moretti, Monica Marzagalli, Patrizia Limonta
Pages: 243-253
Published online on: 24 October 2014

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Article

TIPE2 inhibits TNF-α-induced hepatocellular carcinoma cell metastasis via Erk1/2 downregulation and NF-κB activation

Yue Hua Zhang, Hong Qiong Yan, Fang Wang, Yan Yan Wang, Yi Na Jiang, Yi Nan Wang, Feng Guang Gao
Pages: 254-264
Published online on: 23 October 2014

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Article

Esculetin (6,7-dihydroxycoumarin): A potential cancer chemopreventive agent through suppression of Sp1 in oral squamous cancer cells

Jin Hyoung Cho, Jae-Cheon Shin, Jung-Jae Cho, Yung Hyun Choi, Jung-Hyun Shim, Jung-Il Chae
Pages: 265-271
Published online on: 07 October 2014

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Article

Alteration of epithelial-mesenchymal transition markers in human normal ovaries and neoplastic ovarian cancers

Bo-Rim Yi, Tae-Hee Kim, Ye-Seul Kim, Kyung-Chul Choi
Pages: 272-280
Published online on: 07 October 2014

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Article

Real-time quantitative RT-PCR detection of circulating tumor cells from breast cancer patients

Maowen Guo, Xiaotian Li, Shaohua Zhang, Hua Song, Wenhui Zhang, Xueyi Shang, Yuling Zheng, Hua Jiang, Qingyu Lv, Yongqiang Jiang, Huaijie Hao
Pages: 281-289
Published online on: 29 October 2014

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Article

Upregulation of CRMP4, a new prostate cancer metastasis suppressor gene, inhibits tumor growth in a nude mouse intratibial injection model

Wei Zhou, Peigen Xie, Mao Pang, Bu Yang, Youqiang Fang, Tao Shu, Chang Liu, Xuan Wang, Liangming Zhang, Shangfu Li, Limin Rong
Pages: 290-298
Published online on: 10 October 2014

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Article

Combination of SNX-2112 with 5-FU exhibits antagonistic effect in esophageal cancer cells

Yuting Liu, Xiao Wang, Ying Wang, Yi Zhang, Kai Zheng, Haizhao Yan, Li Zhang, Wenbo Chen, Xiaoyan Wang, Qiuying Liu, Shaoxiang Wang, Yifei Wang
Pages: 299-307
Published online on: 20 October 2014

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Article

Selective anticancer effects and protection from chemotherapy by the botanical compound LCS101: Implications for cancer treatment

Zoya Cohen, Yair Maimon, Merav Yoeli-Lerner, Peiying Yang, Noah Samuels, Raanan Berger
Pages: 308-316
Published online on: 17 October 2014

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Article

SOX2 promotes tumorigenicity and inhibits the differentiation of I-type neuroblastoma cells

Shaobo Yang, Jicui Zheng, Xianmin Xiao, Ting Xu, Weitao Tang, Haitao Zhu, Lin Yang, Shan Zheng, Kuiran Dong, Guomin Zhou, Yang Wang
Pages: 317-323
Published online on: 17 October 2014

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Article

The effect of organic anion-transporting polypeptides 1B1, 1B3 and 2B1 on the antitumor activity of flavopiridol in breast cancer cells

Stefan Brenner, Juliane Riha, Benedikt Giessrigl, Theresia Thalhammer, Michael Grusch, Georg Krupitza, Bruno Stieger, Walter Jäger
Pages: 324-332
Published online on: 24 October 2014

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Article

Decreased expression of the SPOP gene is associated with poor prognosis in glioma

Dacheng Ding, Tao Song, Wu Jun, Zeming Tan, Jiasheng Fang
Pages: 333-341
Published online on: 24 October 2014

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Article

A novel pyrido-thieno-pyrimidine derivative activates p53 through induction of phosphorylation and acetylation in colorectal cancer cells

Mi Ae Kang, Mi-Sook Kim, Ji Young Kim, Young-Joo Shin, Jie-Young Song, Jae-Hoon Jeong
Pages: 342-350
Published online on: 22 October 2014

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Article

The key role of PML in IFN-α induced cellular senescence of human mesenchymal stromal cells

Shan Fu, Jieping Wei, Gang Wang, Binsheng Wang, Yebo Wang, Xiaoyu Lai, He Huang
Pages: 351-359
Published online on: 30 October 2014

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Article

Tetrandrine induces G1/S cell cycle arrest through the ROS/Akt pathway in EOMA cells and inhibits angiogenesis in vivo

Wenkai Xiao, Yajie Jiang, Qiuxu Men, Ling Yuan, Zebo Huang, Ting Liu, Wenhua Li, Xin Liu
Pages: 360-368
Published online on: 29 October 2014

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Article

Assessment of gene promoter G‑quadruplex binding and modulation by a naphthalene diimide derivative in tumor cells

Matteo Nadai, Graziella Cimino‑Reale, Giovanna Sattin, Filippo Doria, Elena Butovskaya, Nadia Zaffaroni, Mauro Freccero, Manlio Palumbo, Sara N. Richter, Marco Folini
Pages: 369-380
Published online on: 23 October 2014

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Article

Long-term health-related quality of life after curative treatment for prostate cancer: A regional cross-sectional comparison of two standard treatment modalities

Marie Hjälm-Eriksson, Bo Lennernäs, Anders Ullén, Hemming Johansson, Jonas Hugosson, Sten Nilsson, Yvonne Brandberg
Pages: 381-388
Published online on: 29 October 2014

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Article

The alkaloid emetine sensitizes ovarian carcinoma cells to cisplatin through downregulation of bcl-xL

Qi Sun, Shingo Yogosawa, Yosuke Iizumi, Toshiyuki Sakai, Yoshihiro Sowa
Pages: 389-394
Published online on: 08 October 2014

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Article

Cks1 proteasomal turnover is a predominant mode of regulation in breast cancer cells: Role of key tyrosines and lysines

Vinayak Khattar, Jaideep V. Thottassery
Pages: 395-406
Published online on: 23 October 2014

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Article

Circulating tumor cells before and during follow-up after breast cancer surgery

Guus van Dalum, Gert Jan van der Stam, Arjan G.J. Tibbe, Bas Franken, Walter J.B. Mastboom, Ivan Vermes, Marco R. de Groot, Leon W.M.M. Terstappen
Pages: 407-413
Published online on: 06 October 2014

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Article

Geographical and anatomical influences on human papillomavirus prevalence diversity in head and neck squamous cell carcinoma in Germany

Elgar Susanne Quabius, Jochen Haag, André Kühnel, Hannes Henry, Anna Sophie Hoffmann, Tibor Görögh, Jürgen Hedderich, Matthias Evert, Achim G. Beule, Steffen Maune, Rainald Knecht, Attila Óvári, Martin Durisin, Florian Hoppe, Silke Tribius, Christoph Röcken, Petra Ambrosch, Markus Hoffmann
Pages: 414-422
Published online on: 07 October 2014

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Article

Multiple roles of extracellular fibroblast growth factors in lung cancer cells

Takahiro Suzuki, Hiroyuki Yasuda, Koji Funaishi, Daisuke Arai, Kota Ishioka, Keiko Ohgino, Tetsuo Tani, Junko Hamamoto, Ayano Ohashi, Katsuhiko Naoki, Tomoko Betsuyaku, Kenzo Soejima
Pages: 423-429
Published online on: 21 October 2014

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Article

Long‑term exposure to gefitinib induces acquired resistance through DNA methylation changes in the EGFR‑mutant PC9 lung cancer cell line

Hideki Terai, Kenzo Soejima, Hiroyuki Yasuda, Takashi Sato, Katsuhiko  Naoki, Shinnosuke Ikemura, Daisuke Arai, Keiko Ohgino, Kota  Ishioka, Junko Hamamoto, Yae Kanai, Tomoko Betsuyaku
Pages: 430-436
Published online on: 29 October 2014

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Journal Cover
April-2026 Volume 68 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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Article Open Access

lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Review Open Access

Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Review Open Access

Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Review Open Access

Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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May-2026 Volume 68 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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