Journal Articles

Article Open Access

Effects of gossypol on apoptosis‑related gene expression in racially distinct triple‑negative breast cancer cells

Samia S. Messeha, Najla O. Zarmouh, Patricia Mendonca, Hayfaa Alwagdani, Carolyn Cotton, Karam F.A. Soliman

Pages: 467-478 Published online on: 31 May 2019
Article Open Access

Matrine improves skeletal muscle atrophy by inhibiting E3 ubiquitin ligases and activating the Akt/mTOR/FoxO3α signaling pathway in C2C12 myotubes and mice

Li Chen, Linlin Chen, Lili Wan, Yan Huo, Jinlu Huang, Jie Li, Jin Lu, Bo Xin, Quanjun Yang, Cheng Guo

Pages: 479-494 Published online on: 19 June 2019
Article Open Access

let‑7 and miR‑17 promote self‑renewal and drive gefitinib resistance in non‑small cell lung cancer

Jun Yin, Weimin Hu, Lei Pan, Wenfan Fu, Lu Dai, Zeyong Jiang, Feng Zhang, Jian Zhao

Pages: 495-508 Published online on: 12 June 2019
Article Open Access

Identification and characterization of a murine model of BCR‑ABL1+ acute B‑lymphoblastic leukemia with central nervous system metastasis

Xiaozhuo Yu, Hua Zhang, Meng Yuan, Ping Zhang, Yang Wang, Mingzhe Zheng, Zhuangwei Lv, Woodvine Otieno Odhiambo, Canyu Li, Chengcheng Liu, Yunfeng Ma, Yanhong Ji

Pages: 521-532 Published online on: 03 June 2019
Article Open Access

Identification of microRNAs associated with the aggressiveness of prolactin pituitary tumors using bioinformatic analysis Corrigendum in /10.3892/or.2021.8081

Zihao Wang, Lu Gao, Xiaopeng Guo, Chenzhe Feng, Kan Deng, Wei Lian, Bing Xing

Pages: 533-548 Published online on: 28 May 2019
Article Open Access

Bile cell‑free DNA as a novel and powerful liquid biopsy for detecting somatic variants in biliary tract cancer

Ningjia Shen, Dadong Zhang, Lei Yin, Yinghe Qiu, Jian Liu, Wenlong Yu, Xiaohui Fu, Bin Zhu, Xiaoya Xu, Anqi Duan, Zishuo Chen, Xiang Wang, Xinkai Cao, Teng Zhao, Zisong Zhou, Lianghe Yu, Hao Qin, Zheng Fang, Jing‑Yu Li, Yuanjin Liu, Lei Xiong, Bo Yuan, Fugen Li, Yongjie Zhang

Pages: 549-560 Published online on: 31 May 2019
Article Open Access

DNA‑PKcs inhibitor increases the sensitivity of gastric cancer cells to radiotherapy

Wei Geng, Dalong Tian, Qiang Wang, Shunlin Shan, Jianwei Zhou, Wenxia Xu, Husheng Shan

Pages: 561-570 Published online on: 06 June 2019
Article Open Access

Knockdown of ribonucleotide reductase regulatory subunit M2 increases the drug sensitivity of chronic myeloid leukemia to imatinib‑based therapy

Chunshui Liu, Yuying Li, Ruiping Hu, Wei Han, Sujun Gao

Pages: 571-580 Published online on: 11 June 2019
Article Open Access

Tumor‑infiltrating M2 macrophages driven by specific genomic alterations are associated with prognosis in bladder cancer

Yongping Xue, Liping Tong, Fei LiuAnwei Liu, Anwei Liu, Shuxiong Zeng, Qiao Xiong, Zeyu Yang, Xing He, Yinghao Sun, Chuanliang Xu

Pages: 581-594 Published online on: 12 June 2019
Article Open Access

IL‑10 secreted by cancer‑associated macrophages regulates proliferation and invasion in gastric cancer cells via c‑Met/STAT3 signaling

Ling Chen, Yuntao Shi, Xiaojuan Zhu, Weiwei Guo, Mingjiong Zhang, Ying Che, Lijuan Tang, Xiaozhong Yang, Qiang You, Zheng Liu

Pages: 595-604 Published online on: 19 June 2019
Article Open Access

Epithelial membrane protein 1 promotes glioblastoma progression through the PI3K/AKT/mTOR signaling pathway

Lifeng Miao, Zheng Jiang, Jiwei Wang, Ning Yang, Qichao Qi, Wenjing Zhou, Zichao Feng, Wenjie Li, Qing Zhang, Bin Huang, Anjing Chen, Di Zhang, Peng Zhao, Xingang Li

Pages: 605-614 Published online on: 19 June 2019
Article Open Access

Comprehensive evaluation of FKBP10 expression and its prognostic potential in gastric cancer

Liang Liang, Kun Zhao, Jin‑Hui Zhu, Gang Chen, Xin‑Gan Qin, Jun‑Qiang Chen

Pages: 615-628 Published online on: 11 June 2019
Article Open Access

Mutual editing of alternative splicing between breast cancer cells and macrophages

Wanbao Ding, Dongdong Li, Peixian Zhang, Lan Shi, Hui Dai, Yan Li, Xin Bao, Yue Wang, Honglei Zhang, Lei Deng

Pages: 629-656 Published online on: 18 June 2019
Article Open Access

CHD1L is associated with poor survival and promotes the proliferation and metastasis of intrahepatic cholangiocarcinoma Corrigendum in /10.3892/or.2019.7262

Shimiao Li, Yi Chai, Yanbao Ding, Tinghao Yuan, Changwen Wu, Changwen Huang

Pages: 657-669 Published online on: 28 May 2019
Article Open Access

Targeting the differentiation of gastric cancer cells (KATO‑III) downregulates epithelial‑mesenchymal and cancer stem cell markers

Shahid Shah, Marc Pocard, Massoud Mirshahi

Pages: 670-678 Published online on: 12 June 2019
Article Open Access

MPZL1 promotes tumor cell proliferation and migration via activation of Src kinase in ovarian cancer

Danni Chen, Lei Cao, Xiaojie Wang

Pages: 679-687 Published online on: 12 June 2019
Article Open Access

Cucurbitacin E inhibits the Yes‑associated protein signaling pathway and suppresses brain metastasis of human non‑small cell lung cancer in a murine model

Ping‑Chih Hsu, Bo Tian, Yi‑Lin Yang, Yu‑Cheng Wang, Shu Liu, Anatoly Urisman, Cheng‑Ta Yang, Zhidong Xu, David M. Jablons, Liang You

Pages: 697-707 Published online on: 20 June 2019
Article

Role of microRNAs in glucocorticoid‑resistant B‑cell precursor acute lymphoblastic leukemia

Naoto Sakurai, Yoshihiro Komada, Ryo Hanaki, Mari Morimoto, Takahiro Ito, Daisuke Nakato, Masahiro Hirayama

Pages: 708-716 Published online on: 10 June 2019
Article

PTPN1 promotes the progression of glioma by activating the MAPK/ERK and PI3K/AKT pathways and is associated with poor patient survival

Tao Jin, Dongbo Li, Tao Yang, Feng Liu, Juan Kong, Yuefei Zhou

Pages: 717-725 Published online on: 31 May 2019
Article

HIF‑1α promotes the stemness of oesophageal squamous cell carcinoma by activating the Wnt/β‑catenin pathway

Zhuan Lv, Rui‑Dong Liu, Xiao‑Qi Chen, Bing Wang, Li‑Feng Li, Ying‑Shu Guo, Xin‑Ju Chen, Xian‑Qing Ren

Pages: 726-734 Published online on: 18 June 2019
Article

Identification of tRNA‑derived fragments in colon cancer by comprehensive small RNA sequencing

Wei Xiong, Xiaoli Wang, Xinyi Cai, Yan Liu, Cheng Li, Qiuyan Liu, Jiyong Qin, Yunfeng Li

Pages: 735-744 Published online on: 31 May 2019
Article

Identification of a long non‑coding RNA‑mediated competitive endogenous RNA network in hepatocellular carcinoma

Hui He, Di Chen, Shimeng Cui, Hailong Piao, Haibo Tang, Xun Wang, Peng Ye, Shi Jin

Pages: 745-752 Published online on: 03 June 2019
Article

Role of transforming growth factor β1 in the inhibition of gastric cancer cell proliferation by melatonin in vitro and in vivo

Hui Liu, Yu Zhu, Hui Zhu, Rong Cai, Kai‑Fang Wang, Jun Song, Ri‑Xiong Wang, Rui‑Xiang Zhou

Pages: 753-762 Published online on: 06 June 2019
Article

Development of high‑resolution melting analysis for ABCB1 promoter methylation: Clinical consequences in breast and ovarian carcinoma

Radka Vaclavikova, Jovana Klajic, Veronika Brynychova, Katerina Elsnerova, Grethe I.G. Alnaes, Jörg Tost, Vessela N. Kristensen, Lukas Rob, Roman Kodet, Petr Skapa, Marcela Mrhalova, Pavel Soucek

Pages: 763-774 Published online on: 05 June 2019
Article

miR‑29 promoter and enhancer methylation identified by pyrosequencing in Burkitt lymhoma cells: Interplay between MYC and miR‑29 regulation

Luciano Mazzoccoli, Marcela Cristina Robaina, Carlos E. Bacchi, Sheila Coelho Soares Lima, Claudete Esteves Klumb

Pages: 775-784 Published online on: 03 June 2019
Article

Activation of AKT/AP1/FoxM1 signaling confers sorafenib resistance to liver cancer cells

Dongjing Yan, Xiaojing Yan, Xufang Dai, Lingxi Chen, Liangbo Sun, Tao Li, Fengtian He, Jiqin Lian, Wangwei Cai

Pages: 785-796 Published online on: 10 June 2019
Article

Keratin 6, induced by chronic cisplatin exposure, confers chemoresistance in human gastric carcinoma cells

Sung‑Chul Lim, Keshab Raj Parajuli, Song Iy Han

Pages: 797-804 Published online on: 18 June 2019
Article

Comparison of cofilin‑1 and Twist‑1 protein expression in human non‑small cell lung cancer tissues

Chun‑Yuan Chang, Shi‑Long Chang, Jyh‑Der Leu, Yu‑Chan Chang, Michael Hsiao, Liang‑Ting Lin, Han‑Nan Lin, Yi‑Jang Lee

Pages: 805-816 Published online on: 10 June 2019
Article

Ethyl pyruvate suppresses the growth, invasion and migration and induces the apoptosis of non‑small cell lung cancer cells via the HMGB1/RAGE axis and the NF‑κB/STAT3 pathway

Qiongqiong Liu, Yansong Huo, Hong Zheng, Jing Zhao, Li Jia, Peiguo Wang

Pages: 817-825 Published online on: 30 May 2019
Article

Sulfasalazine‑induced ferroptosis in breast cancer cells is reduced by the inhibitory effect of estrogen receptor on the transferrin receptor

Haochen Yu, Chengcheng Yang, Lei Jian, Shipeng Guo, Rui Chen, Kang Li, Fanli Qu, Kai Tao, Yong Fu, Feng Luo, Shengchun Liu

Pages: 826-838 Published online on: 06 June 2019
Article

Effect of platinum‑based chemotherapy on the expression of natural killer group 2 member D ligands, programmed cell death‑1 ligand 1 and HLA class I in non‑small cell lung cancer

Riki Okita, Ai Maeda, Katsuhiko Shimizu, Yuji Nojima, Shinsuke Saisho, Masao Nakata

Pages: 839-848 Published online on: 03 June 2019
Article

Downregulation of PDCD4 induced by progesterone is mediated by the PI3K/AKT signaling pathway in human endometrial cancer cells

Xishuang Wang, Yue Li, Lu Wan, Yanping Liu, Yingshuo Sun, Yuqiu Liu, Yongyu Shi, Lining Zhang, Huaiyu Zhou, Jianing Wang, Xiaoyan Wang, Zengtao Wei

Pages: 849-856 Published online on: 18 June 2019
Article

High relative levels of satellite alpha transcripts predict increased risk of bilateral breast cancer and multiple primary cancer in patients with breast cancer and lacking BRCA‑related clinical features

Nao Kakizawa, Koichi Suzuki, Iku Abe, Yuhei Endo, Sawako Tamaki, Hideki Ishikawa, Fumiaki Watanabe, Kosuke Ichida, Masaaki Saito, Kazusige Futsuhara, Fumio Konishi, Toshiki Rikiyama

Pages: 857-865 Published online on: 03 June 2019
Journal Cover

August-2019
Volume 42 Issue 2

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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