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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2012 Volume 5 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Bimodal actions of selenium essential for antioxidant and toxic pro-oxidant activities: The selenium paradox (Review)

Kyung Hee Lee, Daewon Jeong
Pages: 299-304
Published online on: 31 October 2011

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Article Open Access

Multi-step process of human breast carcinogenesis: A role for BRCA1, BECN1, CCND1, PTEN and UVRAG

Tao Wu, Yi Li, Li Gong, Jian-Guo Lu, Xi-Lin Du, Wen-Dong Zhang, Xian-Li He, Jun-Qing Wang
Pages: 305-312
Published online on: 18 October 2011

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Article Open Access

The peripheral zone of the prostate is more prone to tumor development than the transitional zone: Is the ETS family the key?

David Adler, Andreas Lindstrot, Jörg Ellinger, Sebastian  Rogenhofer, Reinhard Buettner, Sven Perner, Nicolas Wernert
Pages: 313-316
Published online on: 27 October 2011

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Article Open Access

Assessment of biological characteristics of mesenchymal stem cells labeled with superparamagnetic iron oxide particles in vitro

Jun-Hui Sun, Yue-Lin Zhang, Su-Ping Qian, Xiao-Bo Yu, Hai‑Yang Xie, Lin Zhou, Shu-Sen Zheng
Pages: 317-320
Published online on: 18 October 2011

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Article

APJ polymorphisms in coronary artery disease patients with and without hypertension

Colomba Falcone, Sara Bozzini, Sandra Schirinzi, Maria Paola Buzzi, Chiara Boiocchi, Rossana Totaro, Marialisa Bondesan, Gabriele Pelissero
Pages: 321-325
Published online on: 21 November 2011

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Article

Enhanced antitumor activity of epirubicin combined with cerulenin in osteosarcoma

Z. L. Liu, G. Wang, Y. Shu, P. A. Zou, Y. Zhou, Q. S. Yin
Pages: 326-330
Published online on: 02 November 2011

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Article

Insulin-induced mTOR activity exhibits anti-hepatitis C virus activity

Toru Muraoka, Tatsuki Ichikawa, Naota Taura, Hisamitsu Miyaaki, Shigeyuki Takeshita, Motohisa Akiyama, Satoshi Miuma, Eisuke Ozawa, Hajime Isomoto, Fuminao Takeshima, Kazuhiko Nakao
Pages: 331-335
Published online on: 03 November 2011

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Article

Role of integrin α1 subunits in gastric cancer patients with peritoneal dissemination

Kazumasa Fukuda, Yoshiro Saikawa, Hiroshi Yagi, Norihito  Wada, Tsunehiro Takahashi, Yuko Kitagawa
Pages: 336-340
Published online on: 21 October 2011

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Article

High glucose conditions suppress the function of bone marrow-derived endothelial progenitor cells via inhibition of the eNOS-caveolin-1 complex

Chunli Cao, Hongkun Zhang, Li Gong, Yunjun He, Nan Zhang
Pages: 341-346
Published online on: 21 October 2011

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Article

Small interfering RNA targeting Krüppel-like factor 8 inhibits U251 glioblastoma cell growth by inducing apoptosis

Weifeng Wan, Ji Zhu, Xiaochuan Sun, Wenyuan Tang
Pages: 347-350
Published online on: 08 November 2011

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Article

Paeoniflorin modulates multidrug resistance of a human gastric cancer cell line via the inhibition of NF-κB activation

Shencun Fang, Wei Zhu, Yingming Zhang, Yongqian Shu, Ping Liu
Pages: 351-356
Published online on: 01 November 2011

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Article

Elevated p-CREB-2 (ser 245) expression is potentially associated with carcinogenesis and development of breast carcinoma

Chui-Feng Fan, Xiao-Yun Mao, En-Hua Wang
Pages: 357-362
Published online on: 02 November 2011

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Article

TUNEL-positive cells in the surgical border of an amputation due to infected diabetic foot

C. Bekker-Méndez, R.M Guzmán-Aguilar, M.A Hernández-Cueto, S. Huerta-Yepez, R.A Jarillo-Luna, E. González-Veyrand, C.R González-Bonilla
Pages: 363-372
Published online on: 07 November 2011

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Article

Down-regulation of osteopontin expression by RNA interference affects cell proliferation and chemotherapy sensitivity of breast cancer MDA-MB-231 cells

Li Yang, Ling Wei, Wei Zhao, Xingwu Wang, Gang Zheng, Meizhu Zheng, Xianrang Song, Wenshu Zuo
Pages: 373-376
Published online on: 21 November 2011

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Article

Disparate clinicopathological correlations of p53 and Bcl-2 in colorectal cancer

Petros C. Papagiorgis, Adamantia E. Zizi, Sophia Tseleni, Ioannis N. Oikonomakis, Leonidas Sofras, Efstratios Patsouris, Nikolaos I. Nikiteas
Pages: 377-382
Published online on: 23 November 2011

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Article

Bcl-2/IgH expression in minimal bone marrow infiltration by follicular lymphoma cells

Yi-Qun Che, Peng Liu, Yue Wang, Chang-Gong Zhang, Ya-Ling Han, Di Shen, Ying Zhang, Cui-Ling Zheng, Jun Qi, Qing-Tao Wang
Pages: 383-387
Published online on: 03 November 2011

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Article

Anti-idiotypic single chain mimicking CA125 linked with tuftsin provides protective immunity against ovarian cancer in mice

Wei Yuan, Guimin Xia, Chen Zhao, Chenguang Sui, Jie Ma
Pages: 388-394
Published online on: 21 October 2011

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Article

Expression of α-crystallin in the retina of human sympathetic ophthalmia

Satoru Kase, Beeran B. Meghpara, Susumu Ishida, Narsing A. Rao
Pages: 395-399
Published online on: 01 November 2011

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Article

Pro-apoptotic role of nuclear factor-κB in adriamycin-induced acute myocardial injury in rats

Fang Wang, Hongli Li, Haoying Shi, Baogui Sun
Pages: 400-404
Published online on: 18 October 2011

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Article

Protective effect of tanshinone IIA on rat kidneys during hypothermic preservation

Xiaoming Zhang, Daqiang He, Linhao Xu, Shucai Ling
Pages: 405-409
Published online on: 19 October 2011

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Article

Differences in Yes-associated protein and mRNA levels in regenerating liver and hepatocellular carcinoma

Cheng Wang, Lin Zhang, Qian He, Xiaobin Feng, Jin Zhu, Zhaolong  Xu, Xiaojun Wang, Fei Chen, Xiaowu Li, Jiahong Dong
Pages: 410-414
Published online on: 19 October 2011

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Article

Expression of midkine and vascular endothelial growth factor in gastric cancer and the association of high levels with poor prognosis and survival

Zhi-Qiang Zhao, Sheng Yang, Hui-Shan Lu
Pages: 415-419
Published online on: 31 October 2011

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Article

Lentivirus-mediated RNA interference of E2F-1 suppresses Tca8113 cell proliferation

Hua Yuan, Fei Jiang, Ruixia Wang, Ming Shen, Ning  Chen
Pages: 420-426
Published online on: 07 November 2011

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Article

Beneficial effects of Acer okamotoanum sap on L-NAME-induced hypertension-like symptoms in a rat model

Hyun Yang, Inho Hwang, Tae-Hyoung Koo, Hyo-Jin Ahn, Sun Kim, Mi-Jin Park, Won-Sil Choi, Ha-Young Kang, In-Gyu Choi, Kyung-Chul Choi, Eui-Bae Jeung
Pages: 427-431
Published online on: 31 October 2011

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Article

Increased levels of calcitonin gene-related peptide in serum accelerate fracture healing following traumatic brain injury

Yang Song, Long Bi, Zhenyu Zhang, Zhaosong Huang, Wei Hou, Xu Lu, Pengxiao Sun, Yisheng Han
Pages: 432-438
Published online on: 26 October 2011

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Article

S-allylcysteine induces cell cycle arrest and apoptosis in androgen-independent human prostate cancer cells

Zhuo Liu, Mingchao Li, Ke Chen, Jun Yang, Ruibao Chen, Tao Wang, Jihong Liu, Weimin Yang, Zhangqun Ye
Pages: 439-443
Published online on: 02 November 2011

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Article

Neuropeptide Y innervation in the vaginal mucosa among patients with pelvic organ prolapse

Jie-Mei Hu, Lin Wang, Xiao Cheng, Li-Hua Zhou, Zhi-Gang Li
Pages: 444-448
Published online on: 25 November 2011

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Article

PRSS1 intron mutations in patients with pancreatic cancer and chronic pancreatitis

Feng Gao, Qi-Cai Liu, Sheng Zhang, Ze-Hao  Zhuang, Cai-Zhu Lin, Xin-Hua Lin
Pages: 449-451
Published online on: 21 November 2011

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Article

RNA interference-mediated silencing of SOCS-1 via lentiviral vector promotes apoptosis of alveolar epithelial cells in vitro

Yan-Rong Qian, Qiu-Rui Zhang, Ting Cheng, Huan-Ying Wan, Min Zhou
Pages: 452-456
Published online on: 11 November 2011

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Article

Mutational analysis of p53 and PTEN in soft tissue sarcoma

Liang Yin, Chun Xia Liu, Wei Xia Nong, Yun Zhao Chen, Yan  Qi, Hong An Li, Wen Hao Hu, Kan Sun, Feng Li
Pages: 457-461
Published online on: 02 November 2011

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Article

Serum MMP-9 is elevated in children with asthma

Zhu Hong, Ya-Mei Lin, Xi Qin, Jiang-Long Peng
Pages: 462-464
Published online on: 02 November 2011

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Article

Vitamin E reduces hepatic fibrosis in mice with Schistosoma japonicum infection

Xuefeng Wang, Rongbo Zhang, Jiuwei Du, Youying Hu, Lifa Xu, Jun Lu, Song Ye
Pages: 465-468
Published online on: 01 November 2011

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Article

Expression of paxillin and FAK mRNA and the related clinical significance in esophageal carcinoma

Hong-Xing Cai, Liu-Cai Yang, Xiang-He Song, Zhou-Ru Liu, Yan-Bo Chen, Guo-Kai Dong
Pages: 469-472
Published online on: 04 November 2011

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Article

Association between mutations of the luteinizing hormone β subunit and female infertility

Jiu-Wei Du, Ke-Yi Xu, Li-Yi Fang, Xin-Lan Qi
Pages: 473-476
Published online on: 21 November 2011

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Article

Thromboxane A2 receptor +795T>C and chemoattractant receptor-homologous molecule expressed on Th2 cells -466T>C gene polymorphisms in patients with aspirin-exacerbated respiratory disease

Kenya Kohyama, Masayuki Hashimoto, Shyuzo Abe, Kazumi Kodaira, Tatsuo Yukawa, Soichiro Hozawa, Junichiro Morioka, Hiroaki Inamura, Megumi Yano, Mayumi Ota, Hironori Sagara, Motohiro Kurosawa
Pages: 477-482
Published online on: 16 November 2011

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Article

Simvastatin protects human osteosarcoma cells from oxidative stress-induced apoptosis through mitochondrial-mediated signaling

Xiao-Hong Zhao, Zhe-Rong Xu, Qin Zhang, Yun-Mei Yang
Pages: 483-488
Published online on: 19 October 2011

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Article

Evaluation of antioxidant, antitumor and immunomodulatory properties of polysaccharide isolated from fruit rind of Punica granatum

Manu M. Joseph, S. R. Aravind, Sheeja Varghese, S. Mini, T. T. Sreelekha
Pages: 489-496
Published online on: 18 October 2011

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Article

Effects of leptin on the expression of fatty acid-binding proteins in human placental cell cultures

Athanasios V. Mousiolis, Panagoula Kollia, Chara Skentou, Ioannis E. Messinis
Pages: 497-502
Published online on: 22 November 2011

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Article

The novel dual PI3K/mTOR inhibitor GDC-0941 synergizes with the MEK inhibitor U0126 in non-small cell lung cancer cells

Zu-Quan Zou, Li-Na Zhang, Feng Wang, Jérôme  Bellenger, Yin-Zhuo Shen, Xiao-Hong Zhang
Pages: 503-508
Published online on: 16 November 2011

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Article

Methylation pattern of the putative tumor-suppressor gene LRRC3B promoter in clear cell renal cell carcinomas

A. G. Kondratov, L. A. Stoliar, S. M. Kvasha, V. V. Gordiyuk, Y. M. Zgonnyk, A. V. Gerashchenko, A. F. Vozianov, A. V. Rynditch, E. R. Zabarovsky, V. I. Kashuba
Pages: 509-512
Published online on: 16 November 2011

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Article

Regulation of rat MOR-1 gene expression after chronic intracerebroventricular administration of morphine

Zhi-Ping Zhu, Ramesh B. Badisa, Donald E. Palm, Carl B. Goodman
Pages: 513-516
Published online on: 15 November 2011

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Article

Polymorphism of the inosine triphosphate pyrophosphatase gene predicts ribavirin-induced anemia in chronic hepatitis C patients

Takashi Nishimura, Rie Osaki, Makoto Shioya, Hirotsugu Imaeda, Tomoki Aomatsu, Takayuki Takeuchi, Yoshiaki Okumura, Yoshihide Fujiyama, Akira Andoh
Pages: 517-520
Published online on: 02 November 2011

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Article

Geranylgeranylacetone protects against myocardial ischemia and reperfusion injury by inhibiting high-mobility group box 1 protein in rats

Neng Wang, Xinwen Min, Dongfeng Li, Peigen He, Libin Zhao
Pages: 521-524
Published online on: 04 November 2011

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Article

Interleukin-28B genotypes determine response to pegylated-interferon plus ribavirin therapy in patients with hepatitis C virus infection

Rie Osaki, Takashi Nishimura, Makoto Shioya, Takayuki Takeuchi, Yoshiaki Okumura, Tamio Nakahara, Shigeki Bamba, Shinobu Nakajo, Yoshihide Fujiyama, Akira Andoh
Pages: 525-528
Published online on: 01 November 2011

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Article

Role of HuR in keratinocyte migration and wound healing

David C. Bosanquet, Lin Ye, Keith G. Harding, Wen G. Jiang
Pages: 529-534
Published online on: 14 November 2011

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Article

Preparation of a composite fibrous membrane loaded with mesalazine and metronidazole by interlaced electrospinning

Zhenran Wang, Jian Suo
Pages: 535-538
Published online on: 09 November 2011

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Article

Combination of branched-chain amino acid and angiotensin‑converting enzyme inhibitor improves liver fibrosis progression in patients with cirrhosis

Hitoshi Yoshiji, Ryuichi Noguchi, Yasuhide Ikenaka, Kosuke Kaji, Yosuke Aihara, Akitoshi Douhara, Junichi Yamao, Masahisa Toyohara, Akira Mitoro, Masayoshi Sawai, Motoyuki Yoshida, Chie Morioka, Masao Fujimoto, Masahito Uemura, Hiroshi Fukui
Pages: 539-544
Published online on: 15 November 2011

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Article

Dynamics of γ-tubulin cytoskeleton in HL-60 leukemia cells undergoing differentiation and apoptosis by all-trans retinoic acid

Ahmad Shariftabrizi, Shahin Ahmadian, Yaghub Pazhang
Pages: 545-551
Published online on: 18 October 2011

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Article

The biological characteristics of glioma stem cells in human glioma cell line SHG44

Lei Liu, Wen-Yu Li, Qiang Chen, Jia-Kun Zheng, Li-Ye Yang
Pages: 552-558
Published online on: 26 October 2011

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Article

Genistein downregulates presenilin 1 and ubiquilin 1 expression

Naoko Okumura, Hitomi Yoshida, Yuri Nishimura, Mutsumi  Murakami, Yasuko Kitagishi, Satoru Matsuda
Pages: 559-561
Published online on: 27 October 2011

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Article

Neuroprotection of desferrioxamine in lipopolysaccharide-induced nigrostriatal dopamine neuron degeneration

Zhen Zhang, Keke Zhang, Xinrui Du, Yanbin Li
Pages: 562-566
Published online on: 09 November 2011

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Article

Clobetasol synergistically diminishes Ciz1 expression with genistein in U937 cells

Naoko Okumura, Hitomi Yoshida, Yuri Nishimura, Yasuko Kitagishi, Satoru Matsuda
Pages: 567-569
Published online on: 04 November 2011

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Article

Reduced ultraviolet-induced DNA damage and apoptosis in human skin with topical application of a photolyase-containing DNA repair enzyme cream: Clues to skin cancer prevention

Enzo Berardesca, Marco Bertona, Karmela Altabas, Velimir Altabas, Enzo Emanuele
Pages: 570-574
Published online on: 11 November 2011

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Article

LY294002 enhances cytotoxicity of temozolomide in glioma by down-regulation of the PI3K/Akt pathway

Lingchao Chen, Lei Han, Zhendong Shi, Kailiang Zhang, Yanwei Liu, Yongri  Zheng, Tao Jiang, Peiyu Pu, Chuanlu Jiang, Chunsheng Kang
Pages: 575-579
Published online on: 11 November 2011

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Article

Proteasome inhibitor bortezomib (PS-341) enhances RANKL-induced MDA-MB-231 breast cancer cell migration

Lingyun Zhang, Yuee Teng, Ye Zhang, Jing Liu, Ling Xu, Jinglei Qu, Kezuo Hou, Yunpeng Liu, Xiujuan Qu
Pages: 580-584
Published online on: 16 November 2011

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Article

Nitric oxide triggers apoptosis in A375 human melanoma cells treated with capsaicin and resveratrol

Min Young Kim
Pages: 585-591
Published online on: 24 November 2011

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Journal Cover
January-2026 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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