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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2013 Volume 8 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Crosstalk between dopamine receptors and the Na+/K+‑ATPase (Review)

Li‑Nan Zhang, Jun‑Xia Li, Liang Hao, Yong‑Jun Sun, Ying‑Hua Xie, Shao‑Mei Wu, Lei Liu, Xiao-Long Chen, Zi-Bin Gao
Pages: 1291-1299
Published online on: 19 September 2013

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Article Open Access

Determination of the density of human nuclear cataract lenses

Ke Xu, Yansheng Hao
Pages: 1300-1304
Published online on: 09 September 2013

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Article

Phosphoinositide 3‑kinase δ/γ inhibition does not prevent concanavalin A‑induced hepatitis

Yuanyuan Liu, Li Xiong, Ying Chang, Jianying Tang, Wei Ang, Tao Yang, Weiyi Pi, Xiaoyan Yang, Weiwei Ye, Youfu Luo, Zhenling Wang
Pages: 1305-1310
Published online on: 22 August 2013

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Case Report

Dilated cardiomyopathy and ovarian dysgenesis in a patient with Malouf syndrome: A case report

Ksenija Gersak, Marusa Strgulc, Vojka Gorjup, Zvezdana Dolenc-Strazar, Vesna Jurcic, Daniel J. Penny, Yuxin Fan
Pages: 1311-1314
Published online on: 05 September 2013

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Article

Erythropoietin reduces brain injury after intracerebral hemorrhagic stroke in rats

Zhen Yu, Ling Tang, Lifen Chen, Jinfang Li, Wanfu Wu, Changlin Hu
Pages: 1315-1322
Published online on: 04 September 2013

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Article

Fibroblast growth factor 2 induces mesenchymal stem cells to differentiate into tenocytes through the MAPK pathway

Tao-Yi Cai, Wei Zhu, Xiong-Sheng Chen, Sheng-Yuan Zhou, Lian-Shun Jia, Yan-Qing Sun
Pages: 1323-1328
Published online on: 04 September 2013

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Article

Impacts of You Gui Wan on the expression of estrogen receptors and angiogenic factors in OVX‑rat vagina: A possible mechanism for the trophic effect of the formula on OVX‑induced vaginal atrophy

Qiao‑Zhi Yin, Hua Lu, Li‑Min Li, Shang‑Mian Yie, Xiang Hu, Zhi‑Bin Liu, Xiao Zheng, Sheng Cao, Zou‑Ying Yao
Pages: 1329-1336
Published online on: 06 September 2013

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Article

GSK‑3β may be involved in hippocampal mossy fiber sprouting in the pentylenetetrazole‑kindling model

Wen-Jiao Huang, Fa-Fa Tian, Jin-Mei Chen, Ting-Hui Guo, Yun‑Feng Ma, Jia Fang, Jing Dang, Ming-Yu Song
Pages: 1337-1342
Published online on: 28 August 2013

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Article

Alterations in the expression of atrial calpains in electrical and structural remodeling during aging and atrial fibrillation

Guo-Jun Xu, Tian-Yi Gan, Bao-Peng Tang, Zu-Heng Chen, Ailiman Mahemuti, Tao Jiang, Jian-Guo Song, Xia Guo, Yao-Dong Li, Xian-Hui Zhou, Yu Zhang, Jin-Xin Li
Pages: 1343-1352
Published online on: 13 September 2013

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Article

Integrated analyses of microRNA and mRNA expression profiles in aggressive papillary thyroid carcinoma

Zhili Yang, Ziming Yuan, Youben Fan, Xianzhao Deng, Qi Zheng
Pages: 1353-1358
Published online on: 24 September 2013

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Article

Progranulin expression in neural stem cells and their differentiated cell lineages: An immunocytochemical study

Lanhai Lü, Li Luo, Yinghong Lu, Lizhi Chen, Jie Xu, Kaihua Guo
Pages: 1359-1364
Published online on: 02 September 2013

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Article

In vitro cytotoxicity of silver nanoparticles in primary rat hepatic stellate cells

Xiaojing Sun, Zhiming Wang, Shengyong Zhai, Yingwen Cheng, Jie Liu, Binbin Liu
Pages: 1365-1372
Published online on: 13 September 2013

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Article

Characterization of amplification patterns and target genes on the short arm of chromosome 7 in early-stage lung adenocarcinoma

Ji Un Kang
Pages: 1373-1378
Published online on: 17 September 2013

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Article

Citrate induces apoptosis of the acute monocytic leukemia U937 cell line through regulation of HIF‑1α signaling

Xiaowei Xu, Baiwen Li, Peijie Huang, Xinjian Wan, Youwen Qin, Lili Zhou, Huixia Liu, Haitao Bai, Yanrong Gao, Chun Wang, Xiangjun Meng
Pages: 1379-1384
Published online on: 24 September 2013

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Article

Structural and functional changes of the coronary arteries in elderly senile patients with essential hypertension

Jun Hu, Fu Zhu, Jun Xie, Xinhai Cheng, Guiyu Chen, Haifen Tai, Shaohua Fan
Pages: 1385-1389
Published online on: 13 September 2013

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Article

Optimization and establishment of RNA interference-mediated knockdown of the progestagen-associated endometrial protein gene in human metastatic melanoma cell lines

Lina Chai, Zhixin Qiao, Jiexi Wang, Minxia Liu, Yan Wang, Xuanlin Wang, Min He, Weijing Li, Qun Yu, Ying Han, Suping Ren
Pages: 1390-1396
Published online on: 13 September 2013

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Article

Ginsenoside Rb1 protects rat retinal ganglion cells against hypoxia and oxidative stress

Zhaochun Liu, Juying Chen, Wendong Huang, Zhi Zeng, Yongfei Yang, Banghao Zhu
Pages: 1397-1403
Published online on: 28 August 2013

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Article

Pyocyanin from Pseudomonas induces IL-8 production through the PKC and NF‑κB pathways in U937 cells

Wenshu Chai, Jia Zhang, Zhitu Zhu, Wei Liu, Dianzhu Pan, Ying Li, Baiyi Chen
Pages: 1404-1410
Published online on: 30 August 2013

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Article

Effects of icariin on the alkline phosphatase activity of human periodontal ligament cells inhibited by lipopolysaccharide

Xue-Chao Lv, Liang-Jia Bi, Ying Jiang, Xiang Wang
Pages: 1411-1415
Published online on: 13 September 2013

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Article

An oncolytic adenovirus expressing interleukin-24 enhances antitumor activities in combination with paclitaxel in breast cancer cells

Lin Fang, Qian Cheng, Jin Bai, Ying-Dong Qi, Jun-Jie Liu, Lian-Tao Li, Jun-Nian Zheng
Pages: 1416-1424
Published online on: 13 September 2013

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Article

Characterization of brivanib therapy response in hepatocellular carcinoma xenografts using 1H HR-MAS spectroscopy and histopathology

Jehoon Yang, Kyoung Doo Song, Jae-Hun Kim, Geun-Ho Im, Seulgi Yoon, Misun Namgung, Jung-Hyun Hwang, Jung Hee Lee, Dongil Choi
Pages: 1425-1431
Published online on: 18 September 2013

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Article

CD39/CD73 and the imbalance of Th17 cells and regulatory T cells in allergic asthma

Lin‑Lin Wang, Hua‑Ping Tang, Guo‑Chao Shi, Huan‑Ying Wan, Wei Tang, Xiao‑Xia Hou, Li‑Na Pan, Bao‑Yu Shi, Lian‑Qin Tao
Pages: 1432-1438
Published online on: 18 September 2013

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Article

Ultrasound microbubbles combined with the NFκB binding motif increase transfection efficiency by enhancing the cytoplasmic and nuclear import of plasmid DNA

Qing Deng, Jin-Ling Chen, Qing Zhou, Bo Hu, Qian Chen, Jia Huang, Rui-Qiang Guo
Pages: 1439-1445
Published online on: 09 September 2013

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Article

Assessment of biological characteristics of adipose tissue‑derived stem cells co‑labeled with Molday ION Rhodamine B™ and green fluorescent protein in vitro

Hua Nan, Jiacheng Huang, Hongmian Li, Qiong Li, Dalie Liu
Pages: 1446-1452
Published online on: 18 September 2013

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Article

Acetylpuerarin increases cell viability and reduces apoptosis in rat hippocampal neurons following oxygen‑glucose deprivation/reperfusion

Dong‑Mei Liu, Zhen‑Hui Wang, Li Liu, Xiu‑Mei Zhang, Feng‑Lan Lou
Pages: 1453-1459
Published online on: 09 September 2013

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Article

Generation and characterization of a polyclonal antibody against human high mobility group box 4

Fen Yang, Runsheng Li, Aizhen Hong, Fei Duan, Yuhua Li
Pages: 1460-1464
Published online on: 24 September 2013

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Article

Effects of aspirin on the ERK and PI3K/Akt signaling pathways in rats with acute pulmonary embolism

Lingcong Wang, Jiannong Wu, Wei Zhang, Yihui Zhi, Yanchun Wu, Ronglin Jiang, Ruhui Yang
Pages: 1465-1471
Published online on: 10 September 2013

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Article

Efficient delivery of miR-122 to regulate cholesterol metabolism using a non-covalent peptide-based strategy

Lilin Wang, Wei Tang, Shirong Yan, Long Zhou, Tao Shen, Xiuqing  Huang, Lin Dou, Mo Wang, Songlin Yu, Jian Li
Pages: 1472-1478
Published online on: 18 September 2013

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Article

Effects of shuangtengbitong tincture on collagen‑induced arthritis in rats

Wei Xu, Huang Li, Kedan Chu, Yuqin Zhang, Haiyin Zheng, Mingqing Huang, Xun Zhang, Lidian Chen
Pages: 1479-1485
Published online on: 18 September 2013

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Article

Regulation of prostate cancer cell migration toward bone marrow stromal cell-conditioned medium by Wnt5a signaling

Fangchun Jin, Xinhua Qu, Qiming Fan, Lei Wang, Tingting Tang, Yongqiang Hao, Kerong Dai
Pages: 1486-1492
Published online on: 23 September 2013

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Article

Robustaside B and para‑hydroxyphenol: Phenolic and antioxidant compounds purified from Cnestis ferruginea D.C induced membrane permeability transition in rat liver mitochondria

Rahmat A. Adisa, Olufunso O. Olorunsogo
Pages: 1493-1498
Published online on: 09 September 2013

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Article

Effect of icariin on cell proliferation and the expression of bone resorption/formation-related markers in human periodontal ligament cells

Zhenhua Pei, Fengqiu Zhang, Zhongying Niu, Shenggen Shi
Pages: 1499-1504
Published online on: 19 September 2013

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Article

Gene silencing of claudin‑6 enhances cell proliferation and migration accompanied with increased MMP‑2 activity via p38 MAPK signaling pathway in human breast epithelium cell line HBL‑100

Yue Ren, Qiong Wu, Yafang Liu, Xiaoming Xu, Chengshi Quan
Pages: 1505-1510
Published online on: 10 September 2013

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Article

The role of CD133 expression in the carcinogenesis and prognosis of patients with lung cancer

Hanbo Le, Fang Zeng, Liyun Xu, Xiaoguang Liu, Yanyan Huang
Pages: 1511-1518
Published online on: 04 September 2013

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Article

Prolongation of rat renal allograft survival by CD4+CD25‑ T cells induced by recipient dendritic cells transfected with IKK2dn

Shen Wang, Han‑Chun Chen, Cai‑Bin Fan, Duan‑Gai Wen, Jian‑Quan Hou, Jun Ouyang
Pages: 1519-1524
Published online on: 17 September 2013

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Article

7,8-dihydroxycoumarin may promote sciatic nerve regeneration by suppressing NF-κB expression in mice

Jian-Shi Du, Qing Zhao, Ying-Li Zhang, Yu Wang, Ming Ma
Pages: 1525-1530
Published online on: 13 September 2013

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Article

Construction of a recombinant eukaryotic human ZHX1 gene expression plasmid and the role of ZHX1 in hepatocellular carcinoma

Jianping Wang, Dejie Liu, Xiaohong Liang, Lifen Gao, Xuetian Yue, Yang Yang, Chunhong Ma, Jun Liu
Pages: 1531-1536
Published online on: 24 September 2013

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Article

Berberine inhibits Wilms' tumor cell progression through upregulation of Wilms' tumor gene on the X chromosome

Yan Liu, Sheng Liu
Pages: 1537-1541
Published online on: 03 September 2013

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Article

Clinical evaluation of a formulation containing Curcuma longa and Boswellia serrata extracts in the management of knee osteoarthritis

Reji Kizhakkedath
Pages: 1542-1548
Published online on: 29 August 2013

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Article

The cancer‑testis antigen NXF2 is activated by the hypomethylating agent decitabine in acute leukemia cells in vitro and in vivo

Jihao Zhou, Yonghui Li, Yushi Yao, Lixin Wang, Li Gao, Xiaoning Gao, Xufeng Luo, Jingxin Li, Mengmeng Jiang, Minhang Zhou, Lili Wang, Li Yu
Pages: 1549-1555
Published online on: 28 August 2013

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Article

Transplantation of bone marrow‑derived endothelial progenitor cells overexpressing Delta‑like‑4 enhances functional neovascularization in ischemic myocardium

Hong Huang, Feng Huang, Jian‑Ping Huang
Pages: 1556-1562
Published online on: 28 August 2013

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Article

Functional profiling of immediate early gene Egr1 in an anorexic mouse model

Jun Huang, Weixi Jiang, Dun Yuan
Pages: 1563-1569
Published online on: 28 August 2013

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Article

Effects of clinical isolates of Streptococcus pneumoniae on THP-1 human monocytic cells

Jin Zhang, Da-Kang Hu, Dong-Guo Wang, Yang Liu, Chi-Bo Liu, Lian-Hua Yu, Ying Qu, Xin-Hua Luo, Jin-Hong Yang, Jian Yu, Shuang‑Chun Liu, Xiang-Yang Li
Pages: 1570-1574
Published online on: 17 September 2013

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Article

In vitro anti-inflammatory effect of picrasmalignan A by the inhibition of iNOS and COX‑2 expression in LPS‑activated macrophage RAW 264.7 cells

Feng Zhao, Lei Chen, Chenchen Bi, Menglin Zhang, Weihua Jiao, Xinsheng Yao
Pages: 1575-1579
Published online on: 30 August 2013

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Article

Effects and mechanisms of curcumin and basil polysaccharide on the invasion of SKOV3 cells and dendritic cells

Jing Lv, Qianqian Shao, Huayang Wang, Huan Shi, Ting Wang, Wenjuan Gao, Bingfeng Song, Guangjuan Zheng, Beihua Kong, Xun Qu
Pages: 1580-1586
Published online on: 18 September 2013

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Article

Immunological evaluation of a novel Mycobacterium tuberculosis antigen, Rv3117, absent in Mycobacterium bovis BCG

Junwei Zhao, Zhanqiang Sun, Hao Pei, Juan Ye, Cuicui Chen, Buka Samten, Shulin Zhang, Xiaokui Guo
Pages: 1587-1593
Published online on: 17 September 2013

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Article

Role of JNK and NF‑κB pathways in Porphyromonas gingivalis LPS‑induced vascular cell adhesion molecule‑1 expression in human aortic endothelial cells

Bin Liu, Jia Wang, Lan Cheng, Jingping Liang
Pages: 1594-1600
Published online on: 17 September 2013

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Article

Rapid diagnosis of aneuploidy in chromosomes 13, 18, 21, X and Y by quantitative fluorescence-PCR combined with short tandem repeat and fluorescence-labeled homologous gene quantitative‑PCR using 4-color fluorescently labeled universal primers

Ju Long, Xuehe Ye, Xunjin Weng, Kepeng Fu, Lei Sun, Wanrong Pang
Pages: 1601-1605
Published online on: 13 September 2013

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Journal Cover
January-2026 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Article Open Access

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Review Open Access

Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Article Open Access

Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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Article Open Access

TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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Article Open Access

CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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Article Open Access

High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Article Open Access

Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Article Open Access

Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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Article Open Access

CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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