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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2003 Volume 12 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Inhibition of lipoxygenase by (-)-epigallocatechin gallate: X-ray analysis at 2.1 Å reveals degradation of EGCG and shows soybean LOX-3 complex with EGC instead

Ewa Skrzypczak-Jankun, Kangjing Zhou, Jerzy Jankun
Pages: 415-420
Published online on: 01 October 2003

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Article

A further case of acute myelomonocytic leukemia with inv(8) chromosomal rearrangement and MOZ-NCOA2 gene fusion

Anne Murati, José Adélaïde, Cornel Popovici, Marie-Joëlle Mozziconacci, Christine Arnoulet, Marina Lafage-Pochitaloff, Danielle Sainty, Daniel Birnbaum, Max Chaffanet
Pages: 423-428
Published online on: 01 October 2003

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Article

In-house cDNA microarray analysis of gene expression profiles involved in SCC cell lines

Tetsuhiro Moriya, Naohiko Seki, Ken Shimada, Masaki Kato, Takashi Yakushiji, Yoshinori Nimura, Katsuhiro Uzawa, Masaki Takiguchi, Hideki Tanzawa
Pages: 429-435
Published online on: 01 October 2003

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Article

Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types

Toshio Kuwai, Shinji Tanaka, Eijiro Kaio, Toru Hiyama, Masanori Ito, Yasuhiko Kitadai, Masaharu Sumii, Masaharu Yoshihara, Ken Haruma, Kazuaki Chayama
Pages: 437-442
Published online on: 01 October 2003

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Article

Somatic mutation of the Caspase-5 gene in human lung cancer

Y. Hosomi, A. Gemma, Y. Hosoya, M. Nara, T. Okano, K. Takenaka, A. Yoshimura, K. Koizumi, K. Shimizu, S. Kudoh
Pages: 443-446
Published online on: 01 October 2003

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Article

Role of stromal thrombospondin-1 in motility and proteolytic activity of oral squamous cell carcinoma cells

Yasutaka Hayashido, Masahiro Nakashima, Kazuhiko Urabe, Hideo Yoshioka, Yukio Yoshioka, Tomoaki Hamana, Hisataka Kitano, Koh-Ichi Koizumi, Tesuji Okamoto
Pages: 447-452
Published online on: 01 October 2003

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Article

Mechanism of apoptotic resistance of human osteosarcoma cell line, HS-Os-1, against irradiation

Yasuhiro Ogawa, Toshiaki Takahashi, Toshihiro Kobayashi, Shinji Kariya, Akihito Nishioka, Hiroo Mizobuchi, Masataka Noguchi, Shinji Hamasato, Toshikazu Tani, Harumichi Seguchi, Shoji Yoshida, Hiroshi Sonobe
Pages: 453-458
Published online on: 01 October 2003

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Article

Mechanism of hydrogen peroxide-induced apoptosis of the human osteosarcoma cell line HS-Os-1

Yasuhiro Ogawa, Toshiaki Takahashi, Toshihiro Kobayashi, Shinji Kariya, Akihito Nishioka, Hiroo Mizobuchi, Masataka Noguchi, Shinji Hamasato, Toshikazu Tani, Harumichi Seguchi, Shoji Yoshida, Hiroshi Sonobe
Pages: 459-463
Published online on: 01 October 2003

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Article

Identification of two novel mutations of IRF6 in Korean families affected with Van der Woude syndrome

Youngho Kim, Jung-Young Park, Tak-Jong Lee, Han-Wook Yoo
Pages: 465-468
Published online on: 01 October 2003

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Article

Factor V Leiden mutation (R506Q) and the risk of advanced retinopathy of prematurity

Sarah Kleinberg, Scott Garrant, Terri Tillen, M. T. Trese, B. S. Shastry
Pages: 469-472
Published online on: 01 October 2003

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Article

Epitalon and colon carcinogenesis in rats: Proliferative activity and apoptosis in colon tumors and mucosa

George Kossoy, Judit Zandbank, Eugenie Tendler, Vladimir Anisimov, Vladimir Khavinson, Irina Popovich, Mark Zabezhinski, Itshak Zusman, Herzl Ben-Hur
Pages: 473-477
Published online on: 01 October 2003

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Article

Silencing of the maspin gene by promoter hypermethylation in thyroid cancer

Carsten Boltze, Regine Schneider-Stock, Claudia Quednow, Raoul Hinze, Christian Mawrin, Arndt Hribaschek, Albert Roessner, Cuong Hoang-Vu
Pages: 479-484
Published online on: 01 October 2003

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Article

Cyclic exercise induces anti-inflammatory signal molecule increases in the plasma of Parkinson's patients

Patrick Cadet, Wei Zhu, Kirk Mantione, Marilyn Rymer, Irving Dardik, Stan Reisman, Sean Hagberg, George B. Stefano
Pages: 485-492
Published online on: 01 October 2003

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Article

Dendritic cell vaccine immunotherapy of cancer targeting MUC1 mucin

Keiichi Kontani, Osamu Taguchi, Yoshitomo Ozaki, Jun Hanaoka, Satoru Sawai, Shuhei Inoue, Hajime Abe, Kazuyoshi Hanasawa, Shozo Fujino
Pages: 493-502
Published online on: 01 October 2003

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Article

Negative regulation of forkhead transcription factor AFX (Foxo4) by CBP-induced acetylation

Masahiro Fukuoka, Hiroaki Daitoku, Mitsutoki Hatta, Hitomi Matsuzaki, Satoshi Umemura, Akiyoshi Fukamizu
Pages: 503-508
Published online on: 01 October 2003

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Article

Absence of Kir6.1/KCNJ8 mutations in Italian patients with abnormal coronary vasomotion

Enzo Emanuele, Colomba Falcone, Maria Carabela, Piercarlo Minoretti, Angela D'Angelo, Lorenza Montagna, Diego Geroldi
Pages: 509-512
Published online on: 01 October 2003

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Article

Modulation by D-glucose anomers of the effect of D-fructose upon 45Ca efflux from prelabelled rat pancreatic islets

Hassan Jijakli, Hai-Xia Zhang, Abdullah Sener, Willy J. Malaisse
Pages: 513-515
Published online on: 01 October 2003

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Article

Effects of progestins of human proliferative endometrium: An in vitro model of potential clinical relevance

Séverine Illouz, Jean-Philippe Dales, Karine Sferlazzo, Stéphane Garcia, Séverine Carpentier-Meunier, Léon Boubli, Marie-Noelle Lavaut, Colette Charpin
Pages: 517-523
Published online on: 01 October 2003

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Article

TK-GFP fusion gene virus vectors as tools for studying the features of HSV-TK/ganciclovir cancer gene therapy in vivo

Tiina Pasanen, Tanja Hakkarainen, Pekka Timonen, Jyrki Parkkinen, Anni Tenhunen, Sami Loimas, Jarmo Wahlfors
Pages: 525-531
Published online on: 01 October 2003

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Article

Integrin-mediated suppression of endotoxin-induced DNA damage in lung endothelial cells is sensitive to poly(ADP-ribose) polymerase-1 gene deletion

Hong Huang, Jane L. McIntosh, Lanyan Fang, Csaba Szabo, Dale G. Hoyt
Pages: 533-540
Published online on: 01 October 2003

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Article

Central role of interleukin-6 in burn induced stimulation of hepatic amino acid transport

Timothy M. Pawlik, Edward A. Carter, Barry P. Bode, Alan J. Fischman, Ronald G. Tompkins
Pages: 541-548
Published online on: 01 October 2003

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Article

Effects of Kupffer cell inhibition on liver function and hepatocellular activity in mice

Hong Ding, Renxiu Peng, Eddie Reed, Qingdi Q. Li
Pages: 549-557
Published online on: 01 October 2003

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Article

Light scattering characterization of synthetic MUC-1 peptides and their behavior in dilute solution

Apostolos K. Rizos, Demetrios A. Spandidos, Elias Krambovitis
Pages: 559-563
Published online on: 01 October 2003

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Article

Cytokines and chemokines in serum and urine as early predictors to identify septic patients on intensive care unit

Koroush Kabir, Hendrik Keller, Guido Grass, Thomas Minor, Frank Stueber, Stefan Schroeder, Christian Putensen, Christian Paul, Christoph Burger, Christoph Rangger, Lewis F. Neville, Guenther Mathiak
Pages: 565-570
Published online on: 01 October 2003

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Article

The long-term oral administration of a product derived from a probiotic, Clostridium butyricum induced no pathological effects in rats

Yoshio Araki, Akira Andoh, Jyou Takizawa, Wataru Takizawa, Yoshihide Fujiyama
Pages: 571-575
Published online on: 01 October 2003

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Article

Decrease in regucalcin level and enhancement of protein tyrosine phosphatase activity in rat brain microsomes with increasing age

Minako Tobisawa, Yoshinori Tsurusaki, Masayoshi Yamaguchi
Pages: 577-580
Published online on: 01 October 2003

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Article

Role of endogenous regucalcin in brain function: Suppression of cytosolic nitric oxide synthase and nuclear protein tyrosine phosphatase activities in brain tissue of transgenic rats

Minako Tobisawa, Masayoshi Yamaguchi
Pages: 581-585
Published online on: 01 October 2003

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Article

Attenuation of renal fibrosis by proteasome inhibition in rat obstructive nephropathy: Possible role of nuclear factor κB

Koichiro Tashiro, Satoshi Tamada, Nobuyuki Kuwabara, Toshiyuki Komiya, Kaori Takekida, Toshihiro Asai, Hiroshi Iwao, Kazunobu Sugimura, Yasuo Matsumura, Masanori Takaoka, Tatsuya Nakatani, Katsuyuki Miura
Pages: 587-592
Published online on: 01 October 2003

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Article

Prolonged exendin-4 administration stimulates pituitary-adrenocortical axis of normal and streptozotocin-induced diabetic rats

Ludwik K. Malendowicz, Giuliano Neri, Gastone G. Nussdorfer, Krzysztof W. Nowak, Agnieszka Zyterska, Agnieszka Ziolkowska
Pages: 593-596
Published online on: 01 October 2003

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Article

Evidence of involvement of CXC-chemokines in proliferation of cultivated human melanocytes

Maja Mockenhaupt, Frank Peters, Ildiko Schwenk-Davoine, Yared Herouy, Ingrid Schraufstätter, Peter Elsner, Johannes Norgauer
Pages: 597-601
Published online on: 01 October 2003

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Article

Microsatellite instability in gastric cancer is closely associated with hMLH1 hypermethylation at the proximal region of the promoter

Kaname Ishiguro, Kazuyuki Kawakami, Kazuya Maeda, Yoshinori Ishida, Kenji Omura, Go Watanabe
Pages: 603-608
Published online on: 01 October 2003

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Article

Gene frequencies of the HPA-1 to HPA-13, Oe and Gov platelet antigen alleles in Taiwanese, Indonesian, Filipino and Thai populations

M. C. Shih, T. C. Liu, I-Ling Lin, S. F. Lin, C. M. Chen, J. G. Chang
Pages: 609-614
Published online on: 01 October 2003

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Article

Enteral alanyl-glutamine supplement promotes intestinal adaptation in rats

Jin Satoh, Tomoyuki Tsujikawa, Yoshihide Fujiyama, Tadao Banba
Pages: 615-620
Published online on: 01 October 2003

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Article

Peroxyl radical scavenging capability of fish sauces measured by the chemiluminescence method

Kazuki Harada, Chiharu Okano, Haruhisa Kadoguchi, Yasue Okubo, Mami Ando, Satoshi Kitao, Yoshiyuki Tamura
Pages: 621-625
Published online on: 01 October 2003

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Article

IL-2, IL-10, IL-15 and TNF are key regulators of murine T-cell lymphoma growth

Maria Jose Cravisaco, Claudia Mongini, Elida Alvarez, Paula Ruybal, Ana Escalada, Mariano Sanchez-Lockhart, Silvia Hajos, Claudia Waldner
Pages: 627-632
Published online on: 01 October 2003

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Article

Induction of macrophage migration inhibitory factor by lysophosphatidic acid: Relevance to tumor growth and angiogenesis

Bailong Sun, Jun Nishihira, Masaki Suzuki, Nobuyuki Fukushima, Teruo Ishibashi, Masao Kondo, Yuji Sato, Satoru Todo
Pages: 633-641
Published online on: 01 October 2003

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Article

Identification and characterization of human BCL9L gene and mouse Bcl9l gene in silico

Masuko Katoh, Masaru Katoh
Pages: 643-649
Published online on: 01 October 2003

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Article

Identification and characterization of human FNBP3 gene in silico

Masuko Katoh, Masaru Katoh
Pages: 651-656
Published online on: 01 October 2003

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Article

Influence of stannous chloride on the adhesive properties of Corynebacterium diphtheriae strains

Sônia Maria Silva de Souza, Raphael Hirata, Lílian Oliveira Moreira, Maria Luiza Gomes, Arnaldo Feitosa Braga de Andrade, Mário Bernardo-Filho, Ana Luíza Mattos-Guaraldi
Pages: 657-661
Published online on: 01 October 2003

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Article

HLM/OSBP2 is expressed in chronic myeloid leukemia

Nathalie Henriques Silva, Marcia Vasconcellos Fournier, Glicinia Pimenta, Wolmar Alcantara Pulcheri, Nelson Spector, Maria Da Gloria da Costa Carvalho
Pages: 663-666
Published online on: 01 October 2003

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Article

Molecular insight into the diagnosis of lymphoma

B. Kusic, M. Dominis, S. Dzebro, M. Antica
Pages: 667-671
Published online on: 01 October 2003

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Article

Inhibition of signal transduction in EGF-dependent epithelial cell lines

U. Wollina, A. Frenkl, B. Knöll, U.-C. Hipler, R. Wetzker
Pages: 673-677
Published online on: 01 October 2003

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Journal Cover
October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of adipocytes and their derived extracellular vesicles in the progression, diagnosis and treatment of liver diseases (Review)

Kangrong Li, Muhammad Zubair, Yongmin Yan, Jiahao Xu
Article Number: 293
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin‑induced murine model of asthma

In Sik Shin, Mee Young Lee, Woo Young Jeon, Na Ra Shin, Chang Seob Seo, Hyekyung Ha
Article Number: 292
Published online on: 20 August 2026

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Review Open Access

Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review)

Denita Charoenthanakitkul, Chaiyaboot Ariyachet
Article Number: 291
Published online on: 20 August 2026

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Review Open Access

Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review)

Siqi Tang, Guoyou Gou, Youjia Liu, Fang Wang, Feihong Shu, Ya Deng, Ting Zhang, Jingyu Xu, Rui Xie
Article Number: 290
Published online on: 18 August 2026

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Review Open Access

Redox biology in PCOS: Biomarkers, mechanistic networks, and targeted interventions (Review)

Yuena Qiu, Xiaojing Guo, Jie An
Article Number: 289
Published online on: 18 August 2026

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Review Open Access

Glucose metabolism in osteoporosis: A potential therapeutic target (Review)

Shengyao Peng, Zhuo Yao, Junzhe Guo, Chi Zhang, Keda Yang, Lin Tao
Article Number: 288
Published online on: 17 August 2026

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Retraction Open Access

[Retracted] Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li
Article Number: 287
Published online on: 17 August 2026

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Article Open Access

α‑Cyperone targets the PAK1‑JNK/NF‑κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model

Hang Hu, Xing Wang, Linlin Guo, Ziling Zeng, Hongmei Tang, Yun Zhang, Jiayao Duan, Kaijin Wang
Article Number: 286
Published online on: 14 August 2026

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Article Open Access

Early high‑frequency spinal cord stimulation modulates the ROS/p38 MAPK/NF‑κB and CXCL10/CXCR3 pathways to alleviate neuropathic pain and promote spinal cord injury repair

Sitong Su, Tao Liu, Honghui Lei, Yang Yu, Caizhi Ma, Xinglang Wang, Haoyuan Chen, Zebin Huang, Meiling Cheng, Tongtong Qian, Fangyong Wang
Article Number: 285
Published online on: 13 August 2026

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Review Open Access

Shared mechanisms of musculoskeletal dysfunction in type 2 diabetes mellitus: Insights into future therapeutic directions (Review)

Zhenhong He, Hanyu Li, Yuhan Luo, Yingying Yu, Siyu Li, Tao Zhang, Dingsu Bao
Article Number: 284
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 283
Published online on: 12 August 2026

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Article Open Access

G protein‑coupled receptor kinase 4 governs early kidney development via STAT3 and Nhe3a

Linh Anna Trúc Vu, Julian Gerhards, Lars D. Maerz, Martin D. Burkhalter, Melanie Philipp
Article Number: 282
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Resistant starch prevents tumorigenesis of dimethylhydrazine‑induced colon tumors via regulation of an ER stress‑mediated mitochondrial apoptosis pathway  

Qiuyu Wang, Peng Wang, Zhigang Xiao
Article Number: 281
Published online on: 10 August 2026

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Review Open Access

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Ziwei Chen, Jiaqi Wu, Wenxi Liu, Jie Tan, Xiaochun Peng, Yanhua Zhang, Gai Liang
Article Number: 280
Published online on: 05 August 2026

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Review Open Access

Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review)

Xiu Yang, Pengcheng Li, Hao Zhao
Article Number: 279
Published online on: 05 August 2026

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Review Open Access

Contribution of p38 MAPK in liver fibrosis: An overview of mechanisms, signaling pathways, and therapeutic targets (Review)

Xueqin Yang, Huarong Li, Hao Ye, Ting Wu, Fangyun Xu, Chao Hu, Chunlei Yu, Pian Ye
Article Number: 278
Published online on: 05 August 2026

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Correction Open Access

[Corrigendum] Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 277
Published online on: 05 August 2026

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Review Open Access

Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review)

Chengzhi Liu, Qiong Wu, Mingzhen Yuan, Mingyue Liu, Xinyu Wang, Jiaqi Shen, Xusheng Cao
Article Number: 276
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Effects of miRNA‑455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Article Number: 275
Published online on: 03 August 2026

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Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

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Article Open Access

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

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Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

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Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

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Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

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Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Review Open Access

Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Interferon regulatory factors orchestrate CD8+ T cell function (Review)

Fa-Xi Wang, Chun-Liang Yang, Shan-Jie Rong, Qi-Jie Chen, Xiong-Tao Yue, Fei Sun
Article Number: 311
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Rapamycin‑induced miR‑30a downregulation inhibits senescence of VSMCs by targeting Beclin1

Pan Tan, Haiqin Wang, Junkun Zhan, Xinyu Ma, Xingjun Cui, Yanjiao Wang, Yi Wang, Jiayu Zhong, Youshuo Liu
Article Number: 310
Published online on: 07 September 2026

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Deciphering the function and mechanism of extracorporeal shock wave therapy in knee osteoarthritis (Review)

Yixuan Chen, Siqi Song, Yuchen Zhu, Shiqi Wang, Jieyuan Hu, Chenxu Liu, Yuchen Cai, Yushi Hu
Article Number: 309
Published online on: 04 September 2026

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Multi‑omics integration in osteoarthritis: Unraveling cell‑type‑specific gene‑metabolite networks for precision medicine (Review)

Ying Yang, Ruichen Zheng, Yun Zhang, Dongmei Ye, Jiale Xie, Changliang Zhu
Article Number: 308
Published online on: 03 September 2026

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Autophagy determines the fate of immune cells by regulating metabolic remodeling and PANoptosis (Review)

Yanan Guo, Xinyue Zhou, Yixiao Tian, Dan Chen, Xiaofeng Xie, Bin Zhou, Yingxia Tian, Yaqing Zhang
Article Number: 307
Published online on: 03 September 2026

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Programmed cell death in metabolic syndrome: From molecular mechanisms to therapeutic strategies (Review)

Jialin Zhong, Maofu Zhang, Yafang Zheng, Cuicui Gong, Yasheng Deng, Lisha Sun, Dongqi Zhou, Qian Zhou, Qiu Chen
Article Number: 306
Published online on: 03 September 2026

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Research progress on lysine acetylation (Review)

Minghui Zhang, Yuqi Zhang, Haoxin Yin, Junyuan Yan, Yingling Dong, Xin Zhao, Tianyi Cui, Bin Lv, Xiumei Gao
Article Number: 305
Published online on: 02 September 2026

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Expression of Concern Open Access

[Expression of Concern] Human ether‑à‑go‑go‑related gene mutation L539fs/47‑hERG leads to cell apoptosis through the endoplasmic reticulum stress pathway

Shuting Ma, Yun Zhao, Miaomiao Cao, Chaofeng Sun
Article Number: 304
Published online on: 02 September 2026

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Review Open Access

Targeting integrated cell death networks in sepsis‑associated acute kidney injury: Shared regulatory nodes and diet‑related small molecule modulation (Review)

Lin Song, Aifeng He, Wei Jiang, Keran Shi, Jing Wang, Lu Xu, Jiangquan Yu, Ruiqiang Zheng
Article Number: 303
Published online on: 31 August 2026

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Article Open Access

Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease

Yuanlong Li, Hua Fan, Xiong Han, Ming Ni, Xiaodan Hou, Hailan Xia, Yinzhu Shi, Lin Zhang, Jun Sun
Article Number: 302
Published online on: 31 August 2026

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Review Open Access

Salvianolic acid monomers against metastasis: Decoding the multilayered interception of EMT, angiogenesis and immune evasion (Review)

Shiting Jiang, Dan Liu, Tingting Wei, Qiwei Shi, Haowen Wang, Yidan Gao, Pingsu Mao, Wenli Yang
Article Number: 301
Published online on: 31 August 2026

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Retraction Open Access

[Retracted] Silencing of decoy receptor 3 (DcR3) expression by siRNA in pancreatic carcinoma cells induces Fas ligand‑mediated apoptosis in vitro and in vivo

Jian Zhou, Shiduo Song, Songbin He, Zhenxin Wang, Bing Zhang, Dechun Li, Dongming Zhu
Article Number: 300
Published online on: 31 August 2026

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Review Open Access

Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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Article Open Access

lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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