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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2004 Volume 13 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Molecular characterisation of chondrocytes in autologous chondrocyte implantation

M. H. Zheng, E. King, Y. Kirilak, L. Huang, J. M. Papadimitriou, D. J. Wood, J. Xu
Pages: 623-628
Published online on: 01 May 2004

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Article

Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis

Naruya Tomita, John Y.S. Kim, Gary H. Gibbons, Lunan Zhang, Yasufumi Kaneda, Rolf A.K. Stahl, Malcom Ogborn, Benoit Venderville, Ryuichi Morishita, Dana Baran, Victro J. Dzau
Pages: 629-636
Published online on: 01 May 2004

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Article

Finb, a multiple zinc finger protein, represses transcription of the human angiotensinogen gene

Shoichi Date, Yutaka Nibu, Kazuyuki Yanai, Jun Hirata, Ken-Ichi Yagami, Akiyoshi Fukamizu
Pages: 637-642
Published online on: 01 May 2004

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Article

Germinated barley foodstuff prolongs remission in patients with ulcerative colitis

Hiroyuki Hanai, Osamu Kanauchi, Keiichi Mitsuyama, Akira Andoh, Ken Takeuchi, Iida Takayuki, Yoshio Araki, Yoshihide Fujiyama, Atsushi Toyonaga, Michio Sata, Atsushi Kojima, Masanobu Fukuda, Tadao Bamba
Pages: 643-647
Published online on: 01 May 2004

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Article

Alterations of endothelin-converting enzyme expression in early and advanced stages of human coronary atherosclerosis

Eishu Hai, Yoshihiro Ikura, Takahiko Naruko, Nobuyuki Shirai, Noriko Yoshimi, Soichiro Kayo, Yoshimi Sugama, Hiroko Fujino, Masahiko Ohsawa, Kazuhiko Tanzawa, Takashi Yokota, Makiko Ueda
Pages: 649-654
Published online on: 01 May 2004

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Article

Reactive oxygen species-producing site in radiation and hydrogen peroxide-induced apoptosis of human peripheral T cells: Involvement of lysosomal membrane destabilization

Yasuhiro Ogawa, Toshihiro Kobayashi, Akihito Nishioka, Shinji Kariya, Takenao Ohnishi, Shinji Hamasato, Harumichi Seguchi, Shoji Yoshida
Pages: 655-660
Published online on: 01 May 2004

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Article

The role of selective COX-2 inhibitors in reactive oxygen species formation in osteosarcoma cells after X-ray irradiation

Toshiaki Takahashi, Yasuhiro Ogawa, Toshihiro Kobayashi, Hiroshi Sonobe, Harumichi Seguchi, Toshikazu Tani, Shoji Yoshida
Pages: 661-664
Published online on: 01 May 2004

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Article

Lipoxygenase inhibitors prevent urological cancer cell growth

Masahide Matsuyama, Rikio Yoshimura, Kenji Tsuchida, Yoshiaki Takemoto, Yoshihiro Segawa, Toshiaki Shinnka, Yutaka Kawahito, Hajime Sano, Tatsuya Nakatani
Pages: 665-668
Published online on: 01 May 2004

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Article

Acute effects of endothelins on endogenous adrenomedullin system in the rat heart: Immunocytochemical and autoradiographic studies

Anna S. Belloni, Diego Guidolin, Silvia Ceretta, Sergio Bova, Gastone G. Nussdorfer
Pages: 669-674
Published online on: 01 May 2004

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Article

Fabrication of high quality cDNA microarray using a small amount of cDNA

Chan Hee Park, Ha Jin Jeong, Jae Jun Jung, Gui Yeon Lee, Sang-Chul Kim, Tae Soo Kim, Sang Hwa Yang, Hyun Cheol Chung, Sun Young Rha
Pages: 675-679
Published online on: 01 May 2004

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Article

Observation of lymphatic vessels in orbital fat of patients with inflammatory conditions: a form fruste of lymphangiogenesis?

F. Fogt, R. L. Zimmerman, T. Daly, R. E. Gausas
Pages: 681-683
Published online on: 01 May 2004

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Article

Detection of germ-cell-tumor-specific gene products in peripheral blood by immunomagnetic tumor cell enrichment followed by RT-PCR

M. Schrader, L. Weissbach, M. Müller, B. Straub, H. Krause, C. Goessl, M. Schostak, H. L. Rittner, S. Stange, K. Miller
Pages: 685-690
Published online on: 01 May 2004

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Article

Carboxyl-terminus of the amyloid protein precursor and ERβ are required for estrogenic effect in activating mitogen-activated protein kinase

Hwa J. Lim, Chul J. Lim, Dae Y. Hwang, Su H. Lee, Sae H. Min, Youn S. Song, Su J. Seo, Hye K. Park, Yhun Y. Sheen, Jung S. Cho, Yong K. Kim
Pages: 691-696
Published online on: 01 May 2004

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Article

Metabolism of 13C-enriched D-fructose in hepatocytes from Goto-Kakizaki rats

Willy J. Malaisse, Laurence Ladriere, Ingrid Verbruggen, Rudolph Willem
Pages: 697-703
Published online on: 01 May 2004

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Article

Osteosarcoma and chondrosarcoma as targets for virus vectors and herpes simplex virus thymidine kinase/ganciclovir gene therapy

Anna Ketola, Ann-Marie Määttä, Tiina Pasanen, Kirsi Tulimäki, Jarmo Wahlfors
Pages: 705-710
Published online on: 01 May 2004

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Article

Protein expression of MMP-13, uPA, and PAI-1 in pseudocapsular and interface tissue around implants of loose artificial hip joints and in osteoarthritis

Peter Diehl, Bernd Hantke, Michael Hennig, Harald Tschesche, Wolfram Mittelmeier, Manfred Schmitt, Bernd Muehlenweg
Pages: 711-715
Published online on: 01 May 2004

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Article

The aqueous extract from Artemisia capillaris Thunb. inhibits lipopolysaccharide-induced inflammatory response through preventing NF-κB activation in human hepatoma cell line and rat liver

Sang Hoon Hong, Sang Ho Seo, Jun Hyuk Lee, Byung Tae Choi
Pages: 717-720
Published online on: 01 May 2004

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Article

Identification of p46 Shc expressed in the nuclei of hepatocytes with high proliferating activity: Study of regenerating rat liver

Jin Yuji, Tsutomu Masaki, Shuhei Yoshida, Yuko Kita, Han Feng, Naohito Uchida, Hitoshi Yoshiji, Akira Kitanaka, Seishiro Watanabe, Kazutaka Kurokohchi, Shigeki Kuriyama
Pages: 721-728
Published online on: 01 May 2004

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Article

Effect of peroxisome proliferator-activated receptor α on human angiotensinogen promoter

Yoko Shimamoto, Keiko Hirota, Akiyoshi Fukamizu
Pages: 729-733
Published online on: 01 May 2004

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Article

Cloning and characterization of a novel human cDNA encoding a J-domain protein (DNAJA5) from the fetal brain

Juxiang Chen, Gang Yin, Yicheng Lu, Meiqing Lou, Haipeng Cheng, Xiaohua Ni, Guohan Hu, Chun Luo, Kang Ying, Yi Xie, Yumin Mao
Pages: 735-740
Published online on: 01 May 2004

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Article

Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of β-catenin and inhibition of β-catenin-mediated transactivation

Melchiorre Cervello, Lydia Giannitrapani, Marzia La Rosa, Monica Notarbartolo, Manuela Labbozzetta, Paola Poma, Giuseppe Montalto, Natale D'Alessandro
Pages: 741-748
Published online on: 01 May 2004

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Article

Identification and characterization of human FCHSD1 and FCHSD2 genes in silico

Masuko Katoh, Masaru Katoh
Pages: 749-754
Published online on: 01 May 2004

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Article Open Access

Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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Retraction Open Access

[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Article Open Access

Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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