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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2004 Volume 13 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Molecular characterisation of chondrocytes in autologous chondrocyte implantation

M. H. Zheng, E. King, Y. Kirilak, L. Huang, J. M. Papadimitriou, D. J. Wood, J. Xu
Pages: 623-628
Published online on: 01 May 2004

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Article

Gene therapy with an E2F transcription factor decoy inhibits cell cycle progression in rat anti-Thy 1 glomerulonephritis

Naruya Tomita, John Y.S. Kim, Gary H. Gibbons, Lunan Zhang, Yasufumi Kaneda, Rolf A.K. Stahl, Malcom Ogborn, Benoit Venderville, Ryuichi Morishita, Dana Baran, Victro J. Dzau
Pages: 629-636
Published online on: 01 May 2004

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Article

Finb, a multiple zinc finger protein, represses transcription of the human angiotensinogen gene

Shoichi Date, Yutaka Nibu, Kazuyuki Yanai, Jun Hirata, Ken-Ichi Yagami, Akiyoshi Fukamizu
Pages: 637-642
Published online on: 01 May 2004

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Article

Germinated barley foodstuff prolongs remission in patients with ulcerative colitis

Hiroyuki Hanai, Osamu Kanauchi, Keiichi Mitsuyama, Akira Andoh, Ken Takeuchi, Iida Takayuki, Yoshio Araki, Yoshihide Fujiyama, Atsushi Toyonaga, Michio Sata, Atsushi Kojima, Masanobu Fukuda, Tadao Bamba
Pages: 643-647
Published online on: 01 May 2004

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Article

Alterations of endothelin-converting enzyme expression in early and advanced stages of human coronary atherosclerosis

Eishu Hai, Yoshihiro Ikura, Takahiko Naruko, Nobuyuki Shirai, Noriko Yoshimi, Soichiro Kayo, Yoshimi Sugama, Hiroko Fujino, Masahiko Ohsawa, Kazuhiko Tanzawa, Takashi Yokota, Makiko Ueda
Pages: 649-654
Published online on: 01 May 2004

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Article

Reactive oxygen species-producing site in radiation and hydrogen peroxide-induced apoptosis of human peripheral T cells: Involvement of lysosomal membrane destabilization

Yasuhiro Ogawa, Toshihiro Kobayashi, Akihito Nishioka, Shinji Kariya, Takenao Ohnishi, Shinji Hamasato, Harumichi Seguchi, Shoji Yoshida
Pages: 655-660
Published online on: 01 May 2004

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Article

The role of selective COX-2 inhibitors in reactive oxygen species formation in osteosarcoma cells after X-ray irradiation

Toshiaki Takahashi, Yasuhiro Ogawa, Toshihiro Kobayashi, Hiroshi Sonobe, Harumichi Seguchi, Toshikazu Tani, Shoji Yoshida
Pages: 661-664
Published online on: 01 May 2004

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Article

Lipoxygenase inhibitors prevent urological cancer cell growth

Masahide Matsuyama, Rikio Yoshimura, Kenji Tsuchida, Yoshiaki Takemoto, Yoshihiro Segawa, Toshiaki Shinnka, Yutaka Kawahito, Hajime Sano, Tatsuya Nakatani
Pages: 665-668
Published online on: 01 May 2004

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Article

Acute effects of endothelins on endogenous adrenomedullin system in the rat heart: Immunocytochemical and autoradiographic studies

Anna S. Belloni, Diego Guidolin, Silvia Ceretta, Sergio Bova, Gastone G. Nussdorfer
Pages: 669-674
Published online on: 01 May 2004

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Article

Fabrication of high quality cDNA microarray using a small amount of cDNA

Chan Hee Park, Ha Jin Jeong, Jae Jun Jung, Gui Yeon Lee, Sang-Chul Kim, Tae Soo Kim, Sang Hwa Yang, Hyun Cheol Chung, Sun Young Rha
Pages: 675-679
Published online on: 01 May 2004

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Article

Observation of lymphatic vessels in orbital fat of patients with inflammatory conditions: a form fruste of lymphangiogenesis?

F. Fogt, R. L. Zimmerman, T. Daly, R. E. Gausas
Pages: 681-683
Published online on: 01 May 2004

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Article

Detection of germ-cell-tumor-specific gene products in peripheral blood by immunomagnetic tumor cell enrichment followed by RT-PCR

M. Schrader, L. Weissbach, M. Müller, B. Straub, H. Krause, C. Goessl, M. Schostak, H. L. Rittner, S. Stange, K. Miller
Pages: 685-690
Published online on: 01 May 2004

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Article

Carboxyl-terminus of the amyloid protein precursor and ERβ are required for estrogenic effect in activating mitogen-activated protein kinase

Hwa J. Lim, Chul J. Lim, Dae Y. Hwang, Su H. Lee, Sae H. Min, Youn S. Song, Su J. Seo, Hye K. Park, Yhun Y. Sheen, Jung S. Cho, Yong K. Kim
Pages: 691-696
Published online on: 01 May 2004

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Article

Metabolism of 13C-enriched D-fructose in hepatocytes from Goto-Kakizaki rats

Willy J. Malaisse, Laurence Ladriere, Ingrid Verbruggen, Rudolph Willem
Pages: 697-703
Published online on: 01 May 2004

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Article

Osteosarcoma and chondrosarcoma as targets for virus vectors and herpes simplex virus thymidine kinase/ganciclovir gene therapy

Anna Ketola, Ann-Marie Määttä, Tiina Pasanen, Kirsi Tulimäki, Jarmo Wahlfors
Pages: 705-710
Published online on: 01 May 2004

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Article

Protein expression of MMP-13, uPA, and PAI-1 in pseudocapsular and interface tissue around implants of loose artificial hip joints and in osteoarthritis

Peter Diehl, Bernd Hantke, Michael Hennig, Harald Tschesche, Wolfram Mittelmeier, Manfred Schmitt, Bernd Muehlenweg
Pages: 711-715
Published online on: 01 May 2004

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Article

The aqueous extract from Artemisia capillaris Thunb. inhibits lipopolysaccharide-induced inflammatory response through preventing NF-κB activation in human hepatoma cell line and rat liver

Sang Hoon Hong, Sang Ho Seo, Jun Hyuk Lee, Byung Tae Choi
Pages: 717-720
Published online on: 01 May 2004

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Article

Identification of p46 Shc expressed in the nuclei of hepatocytes with high proliferating activity: Study of regenerating rat liver

Jin Yuji, Tsutomu Masaki, Shuhei Yoshida, Yuko Kita, Han Feng, Naohito Uchida, Hitoshi Yoshiji, Akira Kitanaka, Seishiro Watanabe, Kazutaka Kurokohchi, Shigeki Kuriyama
Pages: 721-728
Published online on: 01 May 2004

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Article

Effect of peroxisome proliferator-activated receptor α on human angiotensinogen promoter

Yoko Shimamoto, Keiko Hirota, Akiyoshi Fukamizu
Pages: 729-733
Published online on: 01 May 2004

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Article

Cloning and characterization of a novel human cDNA encoding a J-domain protein (DNAJA5) from the fetal brain

Juxiang Chen, Gang Yin, Yicheng Lu, Meiqing Lou, Haipeng Cheng, Xiaohua Ni, Guohan Hu, Chun Luo, Kang Ying, Yi Xie, Yumin Mao
Pages: 735-740
Published online on: 01 May 2004

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Article

Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of β-catenin and inhibition of β-catenin-mediated transactivation

Melchiorre Cervello, Lydia Giannitrapani, Marzia La Rosa, Monica Notarbartolo, Manuela Labbozzetta, Paola Poma, Giuseppe Montalto, Natale D'Alessandro
Pages: 741-748
Published online on: 01 May 2004

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Article

Identification and characterization of human FCHSD1 and FCHSD2 genes in silico

Masuko Katoh, Masaru Katoh
Pages: 749-754
Published online on: 01 May 2004

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Journal Cover
October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of adipocytes and their derived extracellular vesicles in the progression, diagnosis and treatment of liver diseases (Review)

Kangrong Li, Muhammad Zubair, Yongmin Yan, Jiahao Xu
Article Number: 293
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin‑induced murine model of asthma

In Sik Shin, Mee Young Lee, Woo Young Jeon, Na Ra Shin, Chang Seob Seo, Hyekyung Ha
Article Number: 292
Published online on: 20 August 2026

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Review Open Access

Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review)

Denita Charoenthanakitkul, Chaiyaboot Ariyachet
Article Number: 291
Published online on: 20 August 2026

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Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review)

Siqi Tang, Guoyou Gou, Youjia Liu, Fang Wang, Feihong Shu, Ya Deng, Ting Zhang, Jingyu Xu, Rui Xie
Article Number: 290
Published online on: 18 August 2026

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Review Open Access

Redox biology in PCOS: Biomarkers, mechanistic networks, and targeted interventions (Review)

Yuena Qiu, Xiaojing Guo, Jie An
Article Number: 289
Published online on: 18 August 2026

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Review Open Access

Glucose metabolism in osteoporosis: A potential therapeutic target (Review)

Shengyao Peng, Zhuo Yao, Junzhe Guo, Chi Zhang, Keda Yang, Lin Tao
Article Number: 288
Published online on: 17 August 2026

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Retraction Open Access

[Retracted] Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li
Article Number: 287
Published online on: 17 August 2026

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Article Open Access

α‑Cyperone targets the PAK1‑JNK/NF‑κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model

Hang Hu, Xing Wang, Linlin Guo, Ziling Zeng, Hongmei Tang, Yun Zhang, Jiayao Duan, Kaijin Wang
Article Number: 286
Published online on: 14 August 2026

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Article Open Access

Early high‑frequency spinal cord stimulation modulates the ROS/p38 MAPK/NF‑κB and CXCL10/CXCR3 pathways to alleviate neuropathic pain and promote spinal cord injury repair

Sitong Su, Tao Liu, Honghui Lei, Yang Yu, Caizhi Ma, Xinglang Wang, Haoyuan Chen, Zebin Huang, Meiling Cheng, Tongtong Qian, Fangyong Wang
Article Number: 285
Published online on: 13 August 2026

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Review Open Access

Shared mechanisms of musculoskeletal dysfunction in type 2 diabetes mellitus: Insights into future therapeutic directions (Review)

Zhenhong He, Hanyu Li, Yuhan Luo, Yingying Yu, Siyu Li, Tao Zhang, Dingsu Bao
Article Number: 284
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 283
Published online on: 12 August 2026

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Article Open Access

G protein‑coupled receptor kinase 4 governs early kidney development via STAT3 and Nhe3a

Linh Anna Trúc Vu, Julian Gerhards, Lars D. Maerz, Martin D. Burkhalter, Melanie Philipp
Article Number: 282
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Resistant starch prevents tumorigenesis of dimethylhydrazine‑induced colon tumors via regulation of an ER stress‑mediated mitochondrial apoptosis pathway  

Qiuyu Wang, Peng Wang, Zhigang Xiao
Article Number: 281
Published online on: 10 August 2026

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Review Open Access

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Ziwei Chen, Jiaqi Wu, Wenxi Liu, Jie Tan, Xiaochun Peng, Yanhua Zhang, Gai Liang
Article Number: 280
Published online on: 05 August 2026

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Review Open Access

Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review)

Xiu Yang, Pengcheng Li, Hao Zhao
Article Number: 279
Published online on: 05 August 2026

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Review Open Access

Contribution of p38 MAPK in liver fibrosis: An overview of mechanisms, signaling pathways, and therapeutic targets (Review)

Xueqin Yang, Huarong Li, Hao Ye, Ting Wu, Fangyun Xu, Chao Hu, Chunlei Yu, Pian Ye
Article Number: 278
Published online on: 05 August 2026

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Correction Open Access

[Corrigendum] Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 277
Published online on: 05 August 2026

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Review Open Access

Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review)

Chengzhi Liu, Qiong Wu, Mingzhen Yuan, Mingyue Liu, Xinyu Wang, Jiaqi Shen, Xusheng Cao
Article Number: 276
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Effects of miRNA‑455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Article Number: 275
Published online on: 03 August 2026

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Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

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Article Open Access

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

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Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

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Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

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Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

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Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Review Open Access

Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Review Open Access

Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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Journal Cover
November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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