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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April 2006 Volume 17 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Fibrin sealant promotes migration and proliferation of human articular chondrocytes: Possible involvement of thrombin and protease-activated receptors

Yaowanuj Kirilak, Nathan J. Pavlos, Craig R. Willers, Renzhi Han, Haotian Feng, Jiake Xu, Nithiananthan Asokananthan, Geoffrey A. Stewart, Peter Henry, David Wood, Ming H. Zheng
Pages: 551-558
Published online on: 01 April 2006

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Article

Regulation of vascular smooth muscle proliferation and migration by β2-chimaerin, a non-protein kinase C phorbol ester receptor

Mitsuhide Maeda, Seiya Kato, Shintro Fukushima, Utako Kaneyuki, Teruhiko Fujii, Marcelo G. Kazanietz, Koichi Oshima, Minoru Shigemori
Pages: 559-566
Published online on: 01 April 2006

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Article

WISP-2 expression in human salivary gland tumors

Yukinao Kouzu, Katsuhiro Uzawa, Masaki Kato, Morihiro Higo, Yoshinori Nimura, Koji Harada, Tsutomu Numata, Naohiko Seki, Mitsunobu Sato, Hideki Tanzawa
Pages: 567-573
Published online on: 01 April 2006

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Article

Evaluation of the role of RET polymorphisms/haplotypes as modifier loci for MEN 2, and analysis of the correlation with the type of RET mutation in a series of Spanish patients

Raquel María Fernández, Elena Navarro, Guillermo Antiñolo, Macarena Ruiz-Ferrer, Salud Borrego
Pages: 575-581
Published online on: 01 April 2006

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Article

Expression of membrane type-1 matrix metalloproteinase, MT1-MMP in human breast cancer and its impact on invasiveness of breast cancer cells

Wen G. Jiang, Gaynor Davies, Tracey A. Martin, Christian Parr, Gareth Watkins, Malcolm D. Mason, Robert E. Mansel
Pages: 583-590
Published online on: 01 April 2006

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Article

Reduction in energy efficiency induced by expression of the uncoupling protein, UCP1, in mouse liver mitochondria

Pedro González-Muniesa, Fermín I. Milagro, Javier Campión, J. Alfredo Martínez
Pages: 591-597
Published online on: 01 April 2006

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Article

Involvement of ALF in human spermatogenesis and male infertility

Min Huang, Hui Wang, Jianmin Li, Zuomin Zhou, Yong Du, Min Lin, Jiahao Sha
Pages: 599-604
Published online on: 01 April 2006

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Article

Interferon-γ down-regulates expression of tumor necrosis factor-α converting enzyme/a disintegrin and metalloproteinase 17 in activated hepatic stellate cells of rats

Tomohiro Fujita, Chihaya Maesawa, Kanta Oikawa, Hiroyuki Nitta, Go Wakabayashi, Tomoyuki Masuda
Pages: 605-616
Published online on: 01 April 2006

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Expression of FGFRL1, a novel fibroblast growth factor receptor, during embryonic development

Beat Trueb, Sara Taeschler
Pages: 617-620
Published online on: 01 April 2006

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Article

MMP14 gene polymorphisms in chronic obstructive pulmonary disease

Wataru Saitoh, Tohru Sakamoto, Ahmed E. Hegab, Akihiro Nomura, Yukio Ishii, Yuko Morishima, Sachiko Kai, Takashi Iizuka, Takumi Kiwamoto, Yosuke Matsuno, Hosam H. Massoud, Hosny M. Massoud, Khalid M. Hassanein, Kiyohisa Sekizawa
Pages: 621-626
Published online on: 01 April 2006

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Evidence for a specific cell membrane retinol-binding protein transport mechanism in a human keratinocyte line

Janet Huang, Amandio Vieira
Pages: 627-631
Published online on: 01 April 2006

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Article

Atrial natriuretic peptide enhances cortisol secretion from guinea-pig adrenal gland: Evidence for an indirect paracrine mechanism probably involving the local release of medullary catecholamines

Dipali Raha, Cinzia Tortorella, Giuliano Neri, Anita Prasad, Bushra Raza, Ranu Raskar, Rakhi Dubey, Nisarga S. Sen, Carlo Macchi, Ludwick K. Malendowicz, M. Firoz Ahmad, Gastone G. Nussdorfer
Pages: 633-636
Published online on: 01 April 2006

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Article

Enhanced cell-substratum adhesion of E-cadherin-expressing cells is mediated by activation of the small GTPase protein, Rac1

Yuqing Wang, Tadashi Ohkubo, Hirohito Tsubouchi, Masayuki Ozawa
Pages: 637-642
Published online on: 01 April 2006

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Sustained enrichment of liver phospholipids and triglycerides in eicosapentaenoate after a bolus intravenous injection of a medium-chain triglycerides:fish oil emulsion to streptozotocin (Type 1) and Goto-Kakizaki (Type 2) diabetic rats

Yvon A. Carpentier, David Fontaine, Anne Otto, Laurence Portois, Jeanine Fontaine, Willy J. Malaisse
Pages: 643-647
Published online on: 01 April 2006

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Article

Self-regulation of neutrophils during phagocytosis is modified after severe tissue injury

Gábor Pap, József Furész, János Fennt, Gábor C. Kovács, László Nagy, János Hamar
Pages: 649-654
Published online on: 01 April 2006

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Article

Novel mutations in the ENG and ACVRL1 genes causing hereditary hemorrhagic teleangiectasia

Loukas Argyriou, Stefan Twelkemeyer, Irakli Panchulidze, Lars-Erik Wehner, Ute Teske, Wolfgang Engel, Karim Nayernia
Pages: 655-659
Published online on: 01 April 2006

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Article

p38MAPK mediates IL-1-induced down-regulation of aggrecan gene expression in human chondrocytes

Jürgen Radons, Anja Katrin Bosserhoff, Susanne Grässel, Werner Falk, Thomas E.O. Schubert
Pages: 661-668
Published online on: 01 April 2006

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Article

The influence of N- and O-glycosylation inhibitors on the glycosylation profile of cellular membrane proteins and adhesive properties of carcinoma cell lines

Anna Paszkiewicz-Gadek, Halina Porowska, Dorota Lemancewicz, Slawomir Wolczynski, Andrzej Gindzienski
Pages: 669-674
Published online on: 01 April 2006

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Article

In vitro anti-cancer activity of a novel microbial fermentation product on human carcinomas

Chung Hin Chui, Roberto Gambari, Fung Yi Lau, Gregory Yin Ming Cheng, Raymond Siu Ming Wong, Stanton Hon Lung Kok, Johnny Cheuk On Tang, Ivy Tuang Ngo Teo, Filly Cheung, Chor Hing Cheng, Kwok Ping Ho, Albert Sun Chi Chan, Alfonso Wong
Pages: 675-679
Published online on: 01 April 2006

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Article

Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells

Masuko Katoh, Masaru Katoh
Pages: 681-685
Published online on: 01 April 2006

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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