Journal Articles
Review
Cathepsin B-cleavable doxorubicin prodrugs for targeted cancer therapy (Review)
Yan-Jun Zhong, Li-Hua Shao, Yan Li
Pages: 373-383 Published online on: 28 December 2012
Article
Deletion polymorphism at chromosome 3q26.1 and oral squamous cell carcinoma
Homare Kawachi, Keisuke Sugahara, Yasutaka Nakamura, Akira Katakura, Kiyoshi Minaguchi, Takahiko Shibahara
Pages: 384-390 Published online on: 21 December 2012
Article
Human hepatocellular carcinoma cell-specific miRNAs reveal the differential expression of miR-24 and miR-27a in cirrhotic/non-cirrhotic HCC
Alessandro Salvi, Edoardo Abeni, Nazario Portolani, Sergio Barlati, Giuseppina De Petro
Pages: 391-402 Published online on: 28 November 2012
Article
The clinical significance of SWI/SNF complex in pancreatic cancer
Masakatsu Numata, Soichiro Morinaga, Takuo Watanabe, Hiroshi Tamagawa, Naoto Yamamoto, Manabu Shiozawa, Yoshiyasu Nakamura, Yoichi Kameda, Shinichi Okawa, Yasushi Rino, Makoto Akaike, Munetaka Masuda, Yohei Miyagi
Pages: 403-410 Published online on: 30 November 2012
Article
Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma
Osamu Dohi, Kohichiroh Yasui, Yasuyuki Gen, Hisashi Takada, Mio Endo, Kazuhiro Tsuji, Chika Konishi, Nobuhisa Yamada, Hironori Mitsuyoshi, Nobuaki Yagi, Yuji Naito, Shinji Tanaka, Shigeki Arii, Toshikazu Yoshikawa
Pages: 411-418 Published online on: 30 November 2012
Article
PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells
Nan Wu, Tetsuya Kurosu, Gaku Oshikawa, Toshikage Nagao, Osamu Miura
Pages: 419-428 Published online on: 06 December 2012
Article
Suppressive oligodeoxynucleotides synergistically enhance antiproliferative effects of anticancer drugs in A549 human lung cancer cells
Ryohei Takahashi, Takashi Sato, Dennis M. Klinman, Takeshi Shimosato, Takeshi Kaneko, Yoshiaki Ishigatsubo
Pages: 429-436 Published online on: 28 December 2012
Article
p63 regulates cell proliferation and cell cycle progression‑associated genes in stromal cells of giant cell tumor of the bone
Carol Po Ying Lau, Patrick Kwok Shing Ng, Man Shan Li, Stephen Kwok Wing Tsui, Lin Huang, Shekhar Madhukar Kumta
Pages: 437-443 Published online on: 03 December 2012
Article
Mechanisms of cisplatin-induced cell death in malignant mesothelioma cells: Role of inhibitor of apoptosis proteins (IAPs) and caspases
Inez L. Cregan, Arun M. Dharmarajan, Simon A. Fox
Pages: 444-452 Published online on: 28 November 2012
Article
Spheroid body-forming cells in the human gastric cancer cell line MKN-45 possess cancer stem cell properties
Jianming Liu, Lilin Ma, Junfei Xu, Chun Liu, Jianguo Zhang, Jie Liu, Ruixin Chen, Youlang Zhou
Pages: 453-459 Published online on: 29 November 2012
Article
Centrosomal localization of RhoGDIβ and its relevance to mitotic processes in cancer cells
Yong-Sheng Jiang, Masayo Maeda, Mayumi Okamoto, Mikiko Fujii, Ryuichiro Fukutomi, Masato Hori, Masaaki Tatsuka, Takahide Ota
Pages: 460-468 Published online on: 07 December 2012
Article
Ligation of CM1 enhances apoptosis of lung cancer cells through different mechanisms in conformity with EGFR mutation
Hyun-Kyung Lee, Ga Bin Park, Yeong Seok Kim, Hyunkeun Song, V. Courtney Broaddus, Dae Young Hur
Pages: 469-477 Published online on: 07 December 2012
Article
Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis
Masato Komatsu, Tetsuro Yoshimaru, Taisuke Matsuo, Kazuma Kiyotani, Yasuo Miyoshi, Toshihito Tanahashi, Kazuhito Rokutan, Rui Yamaguchi, Ayumu Saito, Seiya Imoto, Satoru Miyano, Yusuke Nakamura, Mitsunori Sasa, Mitsuo Shimada, Toyomasa Katagiri
Pages: 478-506 Published online on: 18 December 2012
Article
Stability of the recombinant anti‑erbB2 scFv‑Fc‑interleukin‑2 fusion protein and its inhibition of HER2‑overexpressing tumor cells
Yu‑Jia Du, Ze‑Min Lin, Ying‑Hua Zhao, Xiu‑Ping Feng, Chang‑Qing Wang, Gang Wang, Chun‑Di Wang, Wei Shi, Jian‑Ping Zuo, Fan Li, Cheng‑Zhong Wang
Pages: 507-516 Published online on: 20 December 2012
Article
Antitumor effect of metformin in esophageal cancer: In vitro study
Mitsuyoshi Kobayashi, Kiyohito Kato, Hisakazu Iwama, Shintaro Fujihara, Noriko Nishiyama, Shima Mimura, Yuka Toyota, Takako Nomura, Kei Nomura, Joji Tani, Hisaaki Miyoshi, Hideki Kobara, Hirohito Mori, Koji Murao, Tsutomu Masaki
Pages: 517-524 Published online on: 29 November 2012
Article
Zoledronic acid significantly enhances radiation‑induced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signaling
Kazutaka Koto, Hiroaki Murata, Shinya Kimura, Yasushi Sawai, Naoyuki Horie, Takaaki Matsui, Kazuteru Ryu, Eishi Ashihara, Taira Maekawa, Toshikazu Kubo, Shinji Fushiki
Pages: 525-534 Published online on: 12 December 2012
Article
HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells
Atsushi Matsumura, Takeshi Kubota, Hiroaki Taiyoh, Hitoshi Fujiwara, Kazuma Okamoto, Daisuke Ichikawa, Atsushi Shiozaki, Shuhei Komatsu, Masayoshi Nakanishi, Yoshiaki Kuriu, Yasutoshi Murayama, Hisashi Ikoma, Toshiya Ochiai, Yukihito Kokuba, Takahiro Nakamura, Kunio Matsumoto, Eigo Otsuji
Pages: 535-542 Published online on: 06 December 2012
Article
Systemic transduction of p16INK4A antitumor peptide inhibits the growth of MBT-2 mouse bladder tumor cell line grafts
Toru Shimazui, Kazuhiro Yoshikawa, Jun Miyazaki, Takahiro Kojima, Hiromu Inai, Satoshi Ando, Hirotsugu Uemura, Kazuhiko Uchida, Hiroyuki Nishiyama
Pages: 543-548 Published online on: 24 December 2012
Article
Ephrin-A1 mRNA is associated with poor prognosis of colorectal cancer
Hirofumi Yamamoto, Mitsuyoshi Tei, Mamoru Uemura, Ichiro Takemasa, Yoshio Uemura, Kohei Murata, Mutsumi Fukunaga, Masayuki Ohue, Tadashi Ohnishi, Kimimasa Ikeda, Takeshi Kato, Shu Okamura, Masakazu Ikenaga, Naotsugu Haraguchi, Junichi Nishimura, Tsunekazu Mizushima, Koshi Mimori, Yuichiro Doki, Masaki Mori
Pages: 549-555 Published online on: 21 December 2012
Article
Extracellular signal-regulated kinase and Akt activation play a critical role in the process of hepatocyte growth factor-induced epithelial-mesenchymal transition
Toshiyuki Tanahashi, Shinji Osada, Atsuko Yamada, Junko Kato, Kazunori Yawata, Ryutaro Mori, Hisashi Imai, Yoshiyuki Sasaki, Shiro Saito, Yoshihiro Tanaka, Kenichi Nonaka, Kazuhiro Yoshida
Pages: 556-564 Published online on: 03 December 2012
Article
The activation of proteinase-activated receptor-1 (PAR1) promotes gastric cancer cell alteration of cellular morphology related to cell motility and invasion
Daisuke Fujimoto, Yasuo Hirono, Takanori Goi, Kanji Katayama, Shigeru Matsukawa, Akio Yamaguchi
Pages: 565-573 Published online on: 14 December 2012
Article
ANT2 suppression by shRNA may be able to exert anticancer effects in HCC further by restoring SOCS1 expression
Ji-Young Jang, Yoon-Kyung Jeon, Choong-Eun Lee, Chul-Woo Kim
Pages: 574-582 Published online on: 13 December 2012
Article
Molecular signatures of basal cell carcinoma susceptibility and pathogenesis: A genomic approach
Elizabeth Rose Heller, Ankit Gor, Dan Wang, Qiang Hu, Alberta Lucchese, Darja Kanduc, Meena Katdare, Song Liu, Animesh A. Sinha
Pages: 583-596 Published online on: 30 November 2012
Article
Smart gold nanoparticles enhance killing effect on cancer cells
Kun Song, Peng Xu, Yongde Meng, Feng Geng, Jie Li, Zhao Li, James Xing, Jie Chen, Beihua Kong
Pages: 597-608 Published online on: 29 November 2012
Article
Stage-dependent expression of PI3K/Akt‑pathway genes in neuroblastoma
Susanne Fransson, Frida Abel, Per Kogner, Tommy Martinsson, Katarina Ejeskär
Pages: 609-616 Published online on: 12 December 2012
Article
Sphingosine kinase 1 promotes tumor progression and confers malignancy phenotypes of colon cancer by regulating the focal adhesion kinase pathway and adhesion molecules
Shi-Quan Liu, Ying-Jie Su, Meng-Bin Qin, Ye-Bo Mao, Jie-An Huang, Guo-Du Tang
Pages: 617-626 Published online on: 12 December 2012
Article
Genetic and epigenetic alterations of steroidogenic factor‑1 in ovarian tumors
Sarah Miller, Nobel Bhasin, Heather Urrego, Krzysztof Moroz, Brian G. Rowan, Meera S. Ramayya, Nick M. Makridakis
Pages: 627-634 Published online on: 28 December 2012
Article
microRNA-372 maintains oncogene characteristics by targeting TNFAIP1 and affects NFκB signaling in human gastric carcinoma cells
Chang Zhou, Xiaofeng Li, Xiaoting Zhang, Xizhi Liu, Zhiwen Tan, Celi Yang, Jian Zhang
Pages: 635-642 Published online on: 13 December 2012
Article
A novel NSAID derivative, phospho-ibuprofen, prevents AOM-induced colon cancer in rats
Nengtai Ouyang, Ping Ji, Jennie L. Williams
Pages: 643-650 Published online on: 28 December 2012
Article
Hedyotis diffusa Willd extract suppresses Sonic hedgehog signaling leading to the inhibition of colorectal cancer angiogenesis
Jiumao Lin, Lihui Wei, Aling Shen, Qiaoyan Cai, Wei Xu, Huang Li, Youzhi Zhan, Zhenfeng Hong, Jun Peng
Pages: 651-656 Published online on: 27 December 2012
Article
NF1 deficiency causes Bcl-xL upregulation in Schwann cells derived from neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors
Ho-Jin Park, Su-Jin Lee, Young Bae Sohn, Hyun-Seok Jin, Jae‑Ho Han, Young-Bae Kim, Hyunee Yim, Seon-Yong Jeong
Pages: 657-666 Published online on: 24 December 2012
Article
miRNA expression profile in human osteosarcoma: Role of miR-1 and miR-133b in proliferation and cell cycle control
Chiara Novello, Laura Pazzaglia, Chiara Cingolani, Amalia Conti, Irene Quattrini, Maria Cristina Manara, Mauro Tognon, Piero Picci, Maria Serena Benassi
Pages: 667-675 Published online on: 28 November 2012
Article
The tumor suppressor gene RhoBTB1 is a novel target of miR-31 in human colon cancer
Rui-Si Xu, Xiao-Dong Wu, Si-Qi Zhang, Chang-Feng Li, Lei Yang, Dan-Dan Li, Bao-Gang Zhang, Ying Zhang, Jing-Peng Jin, Bin Zhang
Pages: 676-682 Published online on: 20 December 2012
Article
Inhibition of p21-activated kinase 4 expression suppresses the proliferation of Hep-2 laryngeal carcinoma cells via activation of the ATM/Chk1/2/p53 pathway
Xin Sun, Bin Liu, Jin Wang, Jun Li, Wen-Yue Ji
Pages: 683-689 Published online on: 29 November 2012
Article
Genetic and epigenetic alterations are involved in the regulation of TPM1 in cholangiocarcinoma
Wei Yang, Xiaoyuan Wang, Wei Zheng, Kedong Li, Haofeng Liu, Yueming Sun
Pages: 690-698 Published online on: 17 December 2012
Article
Absence of death receptor translocation into lipid rafts in acquired TRAIL-resistant NSCLC cells
Wen Ouyang, Chunxu Yang, Simin Zhang, Yu Liu, Bo Yang, Junhong Zhang, Fuxiang Zhou, Yunfeng Zhou, Conghua Xie
Pages: 699-711 Published online on: 20 December 2012
Article
Regulation of the Nijmegen breakage syndrome 1 gene NBS1 by c-myc, p53 and coactivators mediates estrogen protection from DNA damage in breast cancer cells
Rowena Wan, Jianchun Wu, Kaitrin K. Baloue, David L. Crowe
Pages: 712-720 Published online on: 28 December 2012
Article
Honokiol synergizes chemotherapy drugs in multidrug resistant breast cancer cells via enhanced apoptosis and additional programmed necrotic death
Wei Tian, Yongchuan Deng, Ling Li, Haifei He, Jie Sun, Dong Xu
Pages: 721-732 Published online on: 14 December 2012
Article
Genistein, a soy phytoestrogen, prevents the growth of BG-1 ovarian cancer cells induced by 17β-estradiol or bisphenol A via the inhibition of cell cycle progression
Kyung-A Hwang, Nam-Hee Kang, Bo-Rim Yi, Hye-Rim Lee, Min-Ah Park, Kyung-Chul Choi
Pages: 733-740 Published online on: 29 November 2012
Article
Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model
Susan J. Zunino, David H. Storms, John W. Newman, Theresa L. Pedersen, Carl L. Keen, Jonathan M. Ducore
Pages: 741-748 Published online on: 12 December 2012
Article
Inhibition of poly(ADP-ribose) polymerase-1 or poly(ADP‑ribose) glycohydrolase individually, but not in combination, leads to improved chemotherapeutic efficacy in HeLa cells
Xiaoxing Feng, David W. Koh
Pages: 749-756 Published online on: 17 December 2012
Article
miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1
Weiyi Xu, Mingfa Liu, Xueling Peng, Peng Zhou, Jianwen Zhou, Ke Xu, Haixiong Xu, Songshan Jiang
Pages: 757-766 Published online on: 17 December 2012
Article
Inhibition of rapamycin-induced Akt phosphorylation by cotylenin A correlates with their synergistic growth inhibition of cancer cells
Takashi Kasukabe, Junko Okabe-Kado, Yu Haranosono, Nobuo Kato, Yoshio Honma
Pages: 767-775 Published online on: 19 December 2012
Article
