Journal Articles

Open Access

Cathepsin B-cleavable doxorubicin prodrugs for targeted cancer therapy (Review)

Yan-Jun Zhong, Li-Hua Shao, Yan Li

Pages: 373-383 Published online on: 28 December 2012
Open Access

Deletion polymorphism at chromosome 3q26.1 and oral squamous cell carcinoma

Homare Kawachi, Keisuke Sugahara, Yasutaka Nakamura, Akira Katakura, Kiyoshi Minaguchi, Takahiko Shibahara

Pages: 384-390 Published online on: 21 December 2012
Open Access

Human hepatocellular carcinoma cell-specific miRNAs reveal the differential expression of miR-24 and miR-27a in cirrhotic/non-cirrhotic HCC

Alessandro Salvi, Edoardo Abeni, Nazario Portolani, Sergio Barlati, Giuseppina De Petro

Pages: 391-402 Published online on: 28 November 2012
Open Access

The clinical significance of SWI/SNF complex in pancreatic cancer

Masakatsu Numata, Soichiro Morinaga, Takuo Watanabe, Hiroshi Tamagawa, Naoto Yamamoto, Manabu Shiozawa, Yoshiyasu Nakamura, Yoichi Kameda, Shinichi Okawa, Yasushi Rino, Makoto Akaike, Munetaka Masuda, Yohei Miyagi

Pages: 403-410 Published online on: 30 November 2012
Open Access

Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma

Osamu Dohi, Kohichiroh Yasui, Yasuyuki Gen, Hisashi Takada, Mio Endo, Kazuhiro Tsuji, Chika Konishi, Nobuhisa Yamada, Hironori Mitsuyoshi, Nobuaki Yagi, Yuji Naito, Shinji Tanaka, Shigeki Arii, Toshikazu Yoshikawa

Pages: 411-418 Published online on: 30 November 2012
Open Access

PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells

Nan Wu, Tetsuya Kurosu, Gaku Oshikawa, Toshikage Nagao, Osamu Miura

Pages: 419-428 Published online on: 06 December 2012
Open Access

Suppressive oligodeoxynucleotides synergistically enhance antiproliferative effects of anticancer drugs in A549 human lung cancer cells

Ryohei Takahashi, Takashi Sato, Dennis M. Klinman, Takeshi Shimosato, Takeshi Kaneko, Yoshiaki Ishigatsubo

Pages: 429-436 Published online on: 28 December 2012
Open Access

p63 regulates cell proliferation and cell cycle progression‑associated genes in stromal cells of giant cell tumor of the bone

Carol Po Ying Lau, Patrick Kwok Shing Ng, Man Shan Li, Stephen Kwok Wing Tsui, Lin Huang, Shekhar Madhukar Kumta

Pages: 437-443 Published online on: 03 December 2012
Open Access

Mechanisms of cisplatin-induced cell death in malignant mesothelioma cells: Role of inhibitor of apoptosis proteins (IAPs) and caspases

Inez L. Cregan, Arun M. Dharmarajan, Simon A. Fox

Pages: 444-452 Published online on: 28 November 2012
Open Access

Spheroid body-forming cells in the human gastric cancer cell line MKN-45 possess cancer stem cell properties

Jianming Liu, Lilin Ma, Junfei Xu, Chun Liu, Jianguo Zhang, Jie Liu, Ruixin Chen, Youlang Zhou

Pages: 453-459 Published online on: 29 November 2012
Open Access

Centrosomal localization of RhoGDIβ and its relevance to mitotic processes in cancer cells

Yong-Sheng Jiang, Masayo Maeda, Mayumi Okamoto, Mikiko Fujii, Ryuichiro Fukutomi, Masato Hori, Masaaki Tatsuka, Takahide Ota

Pages: 460-468 Published online on: 07 December 2012
Open Access

Ligation of CM1 enhances apoptosis of lung cancer cells through different mechanisms in conformity with EGFR mutation

Hyun-Kyung Lee, Ga Bin Park, Yeong Seok Kim, Hyunkeun Song, V. Courtney Broaddus, Dae Young Hur

Pages: 469-477 Published online on: 07 December 2012

Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis

Masato Komatsu, Tetsuro Yoshimaru, Taisuke Matsuo, Kazuma Kiyotani, Yasuo Miyoshi, Toshihito Tanahashi, Kazuhito Rokutan, Rui Yamaguchi, Ayumu Saito, Seiya Imoto, Satoru Miyano, Yusuke Nakamura, Mitsunori Sasa, Mitsuo Shimada, Toyomasa Katagiri

Pages: 478-506 Published online on: 18 December 2012

Stability of the recombinant anti‑erbB2 scFv‑Fc‑interleukin‑2 fusion protein and its inhibition of HER2‑overexpressing tumor cells

Yu‑Jia Du, Ze‑Min Lin, Ying‑Hua Zhao, Xiu‑Ping Feng, Chang‑Qing Wang, Gang Wang, Chun‑Di Wang, Wei Shi, Jian‑Ping Zuo, Fan Li, Cheng‑Zhong Wang

Pages: 507-516 Published online on: 20 December 2012

Antitumor effect of metformin in esophageal cancer: In vitro study

Mitsuyoshi Kobayashi, Kiyohito Kato, Hisakazu Iwama, Shintaro Fujihara, Noriko Nishiyama, Shima Mimura, Yuka Toyota, Takako Nomura, Kei Nomura, Joji Tani, Hisaaki Miyoshi, Hideki Kobara, Hirohito Mori, Koji Murao, Tsutomu Masaki

Pages: 517-524 Published online on: 29 November 2012

Zoledronic acid significantly enhances radiation‑induced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signaling

Kazutaka Koto, Hiroaki Murata, Shinya Kimura, Yasushi Sawai, Naoyuki Horie, Takaaki Matsui, Kazuteru Ryu, Eishi Ashihara, Taira Maekawa, Toshikazu Kubo, Shinji Fushiki

Pages: 525-534 Published online on: 12 December 2012

HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells

Atsushi Matsumura, Takeshi Kubota, Hiroaki Taiyoh, Hitoshi Fujiwara, Kazuma Okamoto, Daisuke Ichikawa, Atsushi Shiozaki, Shuhei Komatsu, Masayoshi Nakanishi, Yoshiaki Kuriu, Yasutoshi Murayama, Hisashi Ikoma, Toshiya Ochiai, Yukihito Kokuba, Takahiro Nakamura, Kunio Matsumoto, Eigo Otsuji

Pages: 535-542 Published online on: 06 December 2012

Systemic transduction of p16INK4A antitumor peptide inhibits the growth of MBT-2 mouse bladder tumor cell line grafts

Toru Shimazui, Kazuhiro Yoshikawa, Jun Miyazaki, Takahiro Kojima, Hiromu Inai, Satoshi Ando, Hirotsugu Uemura, Kazuhiko Uchida, Hiroyuki Nishiyama

Pages: 543-548 Published online on: 24 December 2012

Ephrin-A1 mRNA is associated with poor prognosis of colorectal cancer

Hirofumi Yamamoto, Mitsuyoshi Tei, Mamoru Uemura, Ichiro Takemasa, Yoshio Uemura, Kohei Murata, Mutsumi Fukunaga, Masayuki Ohue, Tadashi Ohnishi, Kimimasa Ikeda, Takeshi Kato, Shu Okamura, Masakazu Ikenaga, Naotsugu Haraguchi, Junichi Nishimura, Tsunekazu Mizushima, Koshi Mimori, Yuichiro Doki, Masaki Mori

Pages: 549-555 Published online on: 21 December 2012

Extracellular signal-regulated kinase and Akt activation play a critical role in the process of hepatocyte growth factor-induced epithelial-mesenchymal transition

Toshiyuki Tanahashi, Shinji Osada, Atsuko Yamada, Junko Kato, Kazunori Yawata, Ryutaro Mori, Hisashi Imai, Yoshiyuki Sasaki, Shiro Saito, Yoshihiro Tanaka, Kenichi Nonaka, Kazuhiro Yoshida

Pages: 556-564 Published online on: 03 December 2012

The activation of proteinase-activated receptor-1 (PAR1) promotes gastric cancer cell alteration of cellular morphology related to cell motility and invasion

Daisuke Fujimoto, Yasuo Hirono, Takanori Goi, Kanji Katayama, Shigeru Matsukawa, Akio Yamaguchi

Pages: 565-573 Published online on: 14 December 2012

ANT2 suppression by shRNA may be able to exert anticancer effects in HCC further by restoring SOCS1 expression

Ji-Young Jang, Yoon-Kyung Jeon, Choong-Eun Lee, Chul-Woo Kim

Pages: 574-582 Published online on: 13 December 2012

Molecular signatures of basal cell carcinoma susceptibility and pathogenesis: A genomic approach

Elizabeth Rose Heller, Ankit Gor, Dan Wang, Qiang Hu, Alberta Lucchese, Darja Kanduc, Meena Katdare, Song Liu, Animesh A. Sinha

Pages: 583-596 Published online on: 30 November 2012

Smart gold nanoparticles enhance killing effect on cancer cells

Kun Song, Peng Xu, Yongde Meng, Feng Geng, Jie Li, Zhao  Li, James Xing, Jie Chen, Beihua Kong

Pages: 597-608 Published online on: 29 November 2012

Stage-dependent expression of PI3K/Akt‑pathway genes in neuroblastoma

Susanne Fransson, Frida Abel, Per Kogner, Tommy Martinsson, Katarina Ejeskär

Pages: 609-616 Published online on: 12 December 2012

Sphingosine kinase 1 promotes tumor progression and confers malignancy phenotypes of colon cancer by regulating the focal adhesion kinase pathway and adhesion molecules

Shi-Quan Liu, Ying-Jie Su, Meng-Bin Qin, Ye-Bo Mao, Jie-An Huang, Guo-Du Tang

Pages: 617-626 Published online on: 12 December 2012

Genetic and epigenetic alterations of steroidogenic factor‑1 in ovarian tumors

Sarah Miller, Nobel Bhasin, Heather Urrego, Krzysztof Moroz, Brian G. Rowan, Meera S. Ramayya, Nick M. Makridakis

Pages: 627-634 Published online on: 28 December 2012

microRNA-372 maintains oncogene characteristics by targeting TNFAIP1 and affects NFκB signaling in human gastric carcinoma cells

Chang Zhou, Xiaofeng Li, Xiaoting Zhang, Xizhi Liu, Zhiwen Tan, Celi Yang, Jian Zhang

Pages: 635-642 Published online on: 13 December 2012

A novel NSAID derivative, phospho-ibuprofen, prevents AOM-induced colon cancer in rats

Nengtai Ouyang, Ping Ji, Jennie L. Williams

Pages: 643-650 Published online on: 28 December 2012

Hedyotis diffusa Willd extract suppresses Sonic hedgehog signaling leading to the inhibition of colorectal cancer angiogenesis

Jiumao Lin, Lihui Wei, Aling Shen, Qiaoyan Cai, Wei Xu, Huang Li, Youzhi Zhan, Zhenfeng Hong, Jun Peng

Pages: 651-656 Published online on: 27 December 2012

NF1 deficiency causes Bcl-xL upregulation in Schwann cells derived from neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors

Ho-Jin Park, Su-Jin Lee, Young Bae Sohn, Hyun-Seok Jin, Jae‑Ho Han, Young-Bae Kim, Hyunee Yim, Seon-Yong Jeong

Pages: 657-666 Published online on: 24 December 2012

miRNA expression profile in human osteosarcoma: Role of miR-1 and miR-133b in proliferation and cell cycle control

Chiara Novello, Laura Pazzaglia, Chiara Cingolani, Amalia Conti, Irene Quattrini, Maria Cristina Manara, Mauro Tognon, Piero Picci, Maria Serena Benassi

Pages: 667-675 Published online on: 28 November 2012

The tumor suppressor gene RhoBTB1 is a novel target of miR-31 in human colon cancer

Rui-Si Xu, Xiao-Dong Wu, Si-Qi Zhang, Chang-Feng Li, Lei Yang, Dan-Dan Li, Bao-Gang Zhang, Ying Zhang, Jing-Peng Jin, Bin Zhang

Pages: 676-682 Published online on: 20 December 2012

Genetic and epigenetic alterations are involved in the regulation of TPM1 in cholangiocarcinoma

Wei Yang, Xiaoyuan Wang, Wei Zheng, Kedong Li, Haofeng Liu, Yueming Sun

Pages: 690-698 Published online on: 17 December 2012

Absence of death receptor translocation into lipid rafts in acquired TRAIL-resistant NSCLC cells

Wen Ouyang, Chunxu Yang, Simin Zhang, Yu Liu, Bo Yang, Junhong Zhang, Fuxiang Zhou, Yunfeng Zhou, Conghua Xie

Pages: 699-711 Published online on: 20 December 2012

Regulation of the Nijmegen breakage syndrome 1 gene NBS1 by c-myc, p53 and coactivators mediates estrogen protection from DNA damage in breast cancer cells

Rowena Wan, Jianchun Wu, Kaitrin K. Baloue, David L. Crowe

Pages: 712-720 Published online on: 28 December 2012

Honokiol synergizes chemotherapy drugs in multidrug resistant breast cancer cells via enhanced apoptosis and additional programmed necrotic death

Wei Tian, Yongchuan Deng, Ling Li, Haifei He, Jie Sun, Dong Xu

Pages: 721-732 Published online on: 14 December 2012

Genistein, a soy phytoestrogen, prevents the growth of BG-1 ovarian cancer cells induced by 17β-estradiol or bisphenol A via the inhibition of cell cycle progression

Kyung-A Hwang, Nam-Hee Kang, Bo-Rim Yi, Hye-Rim Lee, Min-Ah Park, Kyung-Chul Choi

Pages: 733-740 Published online on: 29 November 2012

Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model

Susan J. Zunino, David H. Storms, John W. Newman, Theresa L. Pedersen, Carl L. Keen, Jonathan M. Ducore

Pages: 741-748 Published online on: 12 December 2012

miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1

Weiyi Xu, Mingfa Liu, Xueling Peng, Peng Zhou, Jianwen Zhou, Ke Xu, Haixiong Xu, Songshan Jiang

Pages: 757-766 Published online on: 17 December 2012

Inhibition of rapamycin-induced Akt phosphorylation by cotylenin A correlates with their synergistic growth inhibition of cancer cells

Takashi Kasukabe, Junko Okabe-Kado, Yu Haranosono, Nobuo Kato, Yoshio Honma

Pages: 767-775 Published online on: 19 December 2012

The microRNA-27a: ZBTB10-specificity protein pathway is involved in follicle stimulating hormone-induced VEGF, Cox2 and survivin expression in ovarian epithelial cancer cells

Yunli Lai, Xuerong Zhang, Zhenbo Zhang, Yuyan Shu, Xiaoling Luo, Yongbin Yang, Xiaojie Wang, Guoping Yang, Linxia Li, Youji Feng

Pages: 776-784 Published online on: 18 December 2012
Journal Cover

Cover Legend PDF

February 2013
Volume 42 Issue 2

Print ISSN: 1019-6439
Online ISSN: 1791-2423

Sign up for eToc alerts

Recommend to Library

Full Size Image