Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 1019-6439 Online ISSN: 1791-2423
presentation
International Journal of Oncology

Join Editorial Board Propose a Special Issue

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

  • Selected Issue
  • Current Issue
  • Forthcoming Issue
  • Special Issues
    • Open Special Issues
    • About Special Issues
  • Trending Articles
    • Most Read
    • Most Cited (Dimensions)
      • Past Two Years
      • Total
    • Most Cited (Crossref)
      • Past Year
      • Total
    • Social Media
      • Past Month
      • Past Year
      • Total
  • Information
    • Information for Authors
    • Contact
    • Editorial Policies
    • Editorial Academy
    • Aims and Scope
    • Abstracting and Indexing
    • Bibliographic Information
  • Archive
Journal Cover
February 2013 Volume 42 Issue 2

Full Size Image

Cover Legend PDF

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Cathepsin B-cleavable doxorubicin prodrugs for targeted cancer therapy (Review)

Yan-Jun Zhong, Li-Hua Shao, Yan Li
Pages: 373-383
Published online on: 28 December 2012

  • View Full Article Download
Article Open Access

Deletion polymorphism at chromosome 3q26.1 and oral squamous cell carcinoma

Homare Kawachi, Keisuke Sugahara, Yasutaka Nakamura, Akira Katakura, Kiyoshi Minaguchi, Takahiko Shibahara
Pages: 384-390
Published online on: 21 December 2012

  • View Full Article Download
Article Open Access

Human hepatocellular carcinoma cell-specific miRNAs reveal the differential expression of miR-24 and miR-27a in cirrhotic/non-cirrhotic HCC

Alessandro Salvi, Edoardo Abeni, Nazario Portolani, Sergio Barlati, Giuseppina De Petro
Pages: 391-402
Published online on: 28 November 2012

  • View Full Article Download
Article Open Access

The clinical significance of SWI/SNF complex in pancreatic cancer

Masakatsu Numata, Soichiro Morinaga, Takuo Watanabe, Hiroshi Tamagawa, Naoto Yamamoto, Manabu Shiozawa, Yoshiyasu Nakamura, Yoichi Kameda, Shinichi Okawa, Yasushi Rino, Makoto Akaike, Munetaka Masuda, Yohei Miyagi
Pages: 403-410
Published online on: 30 November 2012

  • View Full Article Download
Article Open Access

Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma

Osamu Dohi, Kohichiroh Yasui, Yasuyuki Gen, Hisashi Takada, Mio Endo, Kazuhiro Tsuji, Chika Konishi, Nobuhisa Yamada, Hironori Mitsuyoshi, Nobuaki Yagi, Yuji Naito, Shinji Tanaka, Shigeki Arii, Toshikazu Yoshikawa
Pages: 411-418
Published online on: 30 November 2012

  • View Full Article Download
Article Open Access

PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells

Nan Wu, Tetsuya Kurosu, Gaku Oshikawa, Toshikage Nagao, Osamu Miura
Pages: 419-428
Published online on: 06 December 2012

  • View Full Article Download
Article Open Access

Suppressive oligodeoxynucleotides synergistically enhance antiproliferative effects of anticancer drugs in A549 human lung cancer cells

Ryohei Takahashi, Takashi Sato, Dennis M. Klinman, Takeshi Shimosato, Takeshi Kaneko, Yoshiaki Ishigatsubo
Pages: 429-436
Published online on: 28 December 2012

  • View Full Article Download
Article Open Access

p63 regulates cell proliferation and cell cycle progression‑associated genes in stromal cells of giant cell tumor of the bone

Carol Po Ying Lau, Patrick Kwok Shing Ng, Man Shan Li, Stephen Kwok Wing Tsui, Lin Huang, Shekhar Madhukar Kumta
Pages: 437-443
Published online on: 03 December 2012

  • View Full Article Download
Article Open Access

Mechanisms of cisplatin-induced cell death in malignant mesothelioma cells: Role of inhibitor of apoptosis proteins (IAPs) and caspases

Inez L. Cregan, Arun M. Dharmarajan, Simon A. Fox
Pages: 444-452
Published online on: 28 November 2012

  • View Full Article Download
Article Open Access

Spheroid body-forming cells in the human gastric cancer cell line MKN-45 possess cancer stem cell properties

Jianming Liu, Lilin Ma, Junfei Xu, Chun Liu, Jianguo Zhang, Jie Liu, Ruixin Chen, Youlang Zhou
Pages: 453-459
Published online on: 29 November 2012

  • View Full Article Download
Article Open Access

Centrosomal localization of RhoGDIβ and its relevance to mitotic processes in cancer cells

Yong-Sheng Jiang, Masayo Maeda, Mayumi Okamoto, Mikiko Fujii, Ryuichiro Fukutomi, Masato Hori, Masaaki Tatsuka, Takahide Ota
Pages: 460-468
Published online on: 07 December 2012

  • View Full Article Download
Article Open Access

Ligation of CM1 enhances apoptosis of lung cancer cells through different mechanisms in conformity with EGFR mutation

Hyun-Kyung Lee, Ga Bin Park, Yeong Seok Kim, Hyunkeun Song, V. Courtney Broaddus, Dae Young Hur
Pages: 469-477
Published online on: 07 December 2012

  • View Full Article Download
Article

Molecular features of triple negative breast cancer cells by genome-wide gene expression profiling analysis

Masato Komatsu, Tetsuro Yoshimaru, Taisuke Matsuo, Kazuma Kiyotani, Yasuo Miyoshi, Toshihito Tanahashi, Kazuhito Rokutan, Rui Yamaguchi, Ayumu Saito, Seiya Imoto, Satoru Miyano, Yusuke Nakamura, Mitsunori Sasa, Mitsuo Shimada, Toyomasa Katagiri
Pages: 478-506
Published online on: 18 December 2012

  • View Full Article Download
Article

Stability of the recombinant anti‑erbB2 scFv‑Fc‑interleukin‑2 fusion protein and its inhibition of HER2‑overexpressing tumor cells

Yu‑Jia Du, Ze‑Min Lin, Ying‑Hua Zhao, Xiu‑Ping Feng, Chang‑Qing Wang, Gang Wang, Chun‑Di Wang, Wei Shi, Jian‑Ping Zuo, Fan Li, Cheng‑Zhong Wang
Pages: 507-516
Published online on: 20 December 2012

  • View Full Article Download
Article

Antitumor effect of metformin in esophageal cancer: In vitro study

Mitsuyoshi Kobayashi, Kiyohito Kato, Hisakazu Iwama, Shintaro Fujihara, Noriko Nishiyama, Shima Mimura, Yuka Toyota, Takako Nomura, Kei Nomura, Joji Tani, Hisaaki Miyoshi, Hideki Kobara, Hirohito Mori, Koji Murao, Tsutomu Masaki
Pages: 517-524
Published online on: 29 November 2012

  • View Full Article Download
Article

Zoledronic acid significantly enhances radiation‑induced apoptosis against human fibrosarcoma cells by inhibiting radioadaptive signaling

Kazutaka Koto, Hiroaki Murata, Shinya Kimura, Yasushi Sawai, Naoyuki Horie, Takaaki Matsui, Kazuteru Ryu, Eishi Ashihara, Taira Maekawa, Toshikazu Kubo, Shinji Fushiki
Pages: 525-534
Published online on: 12 December 2012

  • View Full Article Download
Article

HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cells

Atsushi Matsumura, Takeshi Kubota, Hiroaki Taiyoh, Hitoshi Fujiwara, Kazuma Okamoto, Daisuke Ichikawa, Atsushi Shiozaki, Shuhei Komatsu, Masayoshi Nakanishi, Yoshiaki Kuriu, Yasutoshi Murayama, Hisashi Ikoma, Toshiya Ochiai, Yukihito Kokuba, Takahiro Nakamura, Kunio Matsumoto, Eigo Otsuji
Pages: 535-542
Published online on: 06 December 2012

  • View Full Article Download
Article

Systemic transduction of p16INK4A antitumor peptide inhibits the growth of MBT-2 mouse bladder tumor cell line grafts

Toru Shimazui, Kazuhiro Yoshikawa, Jun Miyazaki, Takahiro Kojima, Hiromu Inai, Satoshi Ando, Hirotsugu Uemura, Kazuhiko Uchida, Hiroyuki Nishiyama
Pages: 543-548
Published online on: 24 December 2012

  • View Full Article Download
Article

Ephrin-A1 mRNA is associated with poor prognosis of colorectal cancer

Hirofumi Yamamoto, Mitsuyoshi Tei, Mamoru Uemura, Ichiro Takemasa, Yoshio Uemura, Kohei Murata, Mutsumi Fukunaga, Masayuki Ohue, Tadashi Ohnishi, Kimimasa Ikeda, Takeshi Kato, Shu Okamura, Masakazu Ikenaga, Naotsugu Haraguchi, Junichi Nishimura, Tsunekazu Mizushima, Koshi Mimori, Yuichiro Doki, Masaki Mori
Pages: 549-555
Published online on: 21 December 2012

  • View Full Article Download
Article

Extracellular signal-regulated kinase and Akt activation play a critical role in the process of hepatocyte growth factor-induced epithelial-mesenchymal transition

Toshiyuki Tanahashi, Shinji Osada, Atsuko Yamada, Junko Kato, Kazunori Yawata, Ryutaro Mori, Hisashi Imai, Yoshiyuki Sasaki, Shiro Saito, Yoshihiro Tanaka, Kenichi Nonaka, Kazuhiro Yoshida
Pages: 556-564
Published online on: 03 December 2012

  • View Full Article Download
Article

The activation of proteinase-activated receptor-1 (PAR1) promotes gastric cancer cell alteration of cellular morphology related to cell motility and invasion

Daisuke Fujimoto, Yasuo Hirono, Takanori Goi, Kanji Katayama, Shigeru Matsukawa, Akio Yamaguchi
Pages: 565-573
Published online on: 14 December 2012

  • View Full Article Download
Article

ANT2 suppression by shRNA may be able to exert anticancer effects in HCC further by restoring SOCS1 expression

Ji-Young Jang, Yoon-Kyung Jeon, Choong-Eun Lee, Chul-Woo Kim
Pages: 574-582
Published online on: 13 December 2012

  • View Full Article Download
Article

Molecular signatures of basal cell carcinoma susceptibility and pathogenesis: A genomic approach

Elizabeth Rose Heller, Ankit Gor, Dan Wang, Qiang Hu, Alberta Lucchese, Darja Kanduc, Meena Katdare, Song Liu, Animesh A. Sinha
Pages: 583-596
Published online on: 30 November 2012

  • View Full Article Download
Article

Smart gold nanoparticles enhance killing effect on cancer cells

Kun Song, Peng Xu, Yongde Meng, Feng Geng, Jie Li, Zhao  Li, James Xing, Jie Chen, Beihua Kong
Pages: 597-608
Published online on: 29 November 2012

  • View Full Article Download
Article

Stage-dependent expression of PI3K/Akt‑pathway genes in neuroblastoma

Susanne Fransson, Frida Abel, Per Kogner, Tommy Martinsson, Katarina Ejeskär
Pages: 609-616
Published online on: 12 December 2012

  • View Full Article Download
Article

Sphingosine kinase 1 promotes tumor progression and confers malignancy phenotypes of colon cancer by regulating the focal adhesion kinase pathway and adhesion molecules

Shi-Quan Liu, Ying-Jie Su, Meng-Bin Qin, Ye-Bo Mao, Jie-An Huang, Guo-Du Tang
Pages: 617-626
Published online on: 12 December 2012

  • View Full Article Download
Article

Genetic and epigenetic alterations of steroidogenic factor‑1 in ovarian tumors

Sarah Miller, Nobel Bhasin, Heather Urrego, Krzysztof Moroz, Brian G. Rowan, Meera S. Ramayya, Nick M. Makridakis
Pages: 627-634
Published online on: 28 December 2012

  • View Full Article Download
Article

microRNA-372 maintains oncogene characteristics by targeting TNFAIP1 and affects NFκB signaling in human gastric carcinoma cells

Chang Zhou, Xiaofeng Li, Xiaoting Zhang, Xizhi Liu, Zhiwen Tan, Celi Yang, Jian Zhang
Pages: 635-642
Published online on: 13 December 2012

  • View Full Article Download
Article

A novel NSAID derivative, phospho-ibuprofen, prevents AOM-induced colon cancer in rats

Nengtai Ouyang, Ping Ji, Jennie L. Williams
Pages: 643-650
Published online on: 28 December 2012

  • View Full Article Download
Article

Hedyotis diffusa Willd extract suppresses Sonic hedgehog signaling leading to the inhibition of colorectal cancer angiogenesis

Jiumao Lin, Lihui Wei, Aling Shen, Qiaoyan Cai, Wei Xu, Huang Li, Youzhi Zhan, Zhenfeng Hong, Jun Peng
Pages: 651-656
Published online on: 27 December 2012

  • View Full Article Download
Article

NF1 deficiency causes Bcl-xL upregulation in Schwann cells derived from neurofibromatosis type 1-associated malignant peripheral nerve sheath tumors

Ho-Jin Park, Su-Jin Lee, Young Bae Sohn, Hyun-Seok Jin, Jae‑Ho Han, Young-Bae Kim, Hyunee Yim, Seon-Yong Jeong
Pages: 657-666
Published online on: 24 December 2012

  • View Full Article Download
Article

miRNA expression profile in human osteosarcoma: Role of miR-1 and miR-133b in proliferation and cell cycle control

Chiara Novello, Laura Pazzaglia, Chiara Cingolani, Amalia Conti, Irene Quattrini, Maria Cristina Manara, Mauro Tognon, Piero Picci, Maria Serena Benassi
Pages: 667-675
Published online on: 28 November 2012

  • View Full Article Download
Article

The tumor suppressor gene RhoBTB1 is a novel target of miR-31 in human colon cancer

Rui-Si Xu, Xiao-Dong Wu, Si-Qi Zhang, Chang-Feng Li, Lei Yang, Dan-Dan Li, Bao-Gang Zhang, Ying Zhang, Jing-Peng Jin, Bin Zhang
Pages: 676-682
Published online on: 20 December 2012

  • View Full Article Download
Article

Inhibition of p21-activated kinase 4 expression suppresses the proliferation of Hep-2 laryngeal carcinoma cells via activation of the ATM/Chk1/2/p53 pathway

Xin Sun, Bin Liu, Jin Wang, Jun Li, Wen-Yue Ji
Pages: 683-689
Published online on: 29 November 2012

  • View Full Article Download
Article

Genetic and epigenetic alterations are involved in the regulation of TPM1 in cholangiocarcinoma

Wei Yang, Xiaoyuan Wang, Wei Zheng, Kedong Li, Haofeng Liu, Yueming Sun
Pages: 690-698
Published online on: 17 December 2012

  • View Full Article Download
Article

Absence of death receptor translocation into lipid rafts in acquired TRAIL-resistant NSCLC cells

Wen Ouyang, Chunxu Yang, Simin Zhang, Yu Liu, Bo Yang, Junhong Zhang, Fuxiang Zhou, Yunfeng Zhou, Conghua Xie
Pages: 699-711
Published online on: 20 December 2012

  • View Full Article Download
Article

Regulation of the Nijmegen breakage syndrome 1 gene NBS1 by c-myc, p53 and coactivators mediates estrogen protection from DNA damage in breast cancer cells

Rowena Wan, Jianchun Wu, Kaitrin K. Baloue, David L. Crowe
Pages: 712-720
Published online on: 28 December 2012

  • View Full Article Download
Article

Honokiol synergizes chemotherapy drugs in multidrug resistant breast cancer cells via enhanced apoptosis and additional programmed necrotic death

Wei Tian, Yongchuan Deng, Ling Li, Haifei He, Jie Sun, Dong Xu
Pages: 721-732
Published online on: 14 December 2012

  • Download
Article

Genistein, a soy phytoestrogen, prevents the growth of BG-1 ovarian cancer cells induced by 17β-estradiol or bisphenol A via the inhibition of cell cycle progression

Kyung-A Hwang, Nam-Hee Kang, Bo-Rim Yi, Hye-Rim Lee, Min-Ah Park, Kyung-Chul Choi
Pages: 733-740
Published online on: 29 November 2012

  • View Full Article Download
Article

Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model

Susan J. Zunino, David H. Storms, John W. Newman, Theresa L. Pedersen, Carl L. Keen, Jonathan M. Ducore
Pages: 741-748
Published online on: 12 December 2012

  • View Full Article Download
Article

Inhibition of poly(ADP-ribose) polymerase-1 or poly(ADP‑ribose) glycohydrolase individually, but not in combination, leads to improved chemotherapeutic efficacy in HeLa cells

Xiaoxing Feng, David W. Koh
Pages: 749-756
Published online on: 17 December 2012

  • View Full Article Download
Article

miR-24-3p and miR-27a-3p promote cell proliferation in glioma cells via cooperative regulation of MXI1

Weiyi Xu, Mingfa Liu, Xueling Peng, Peng Zhou, Jianwen Zhou, Ke Xu, Haixiong Xu, Songshan Jiang
Pages: 757-766
Published online on: 17 December 2012

  • View Full Article Download
Article

Inhibition of rapamycin-induced Akt phosphorylation by cotylenin A correlates with their synergistic growth inhibition of cancer cells

Takashi Kasukabe, Junko Okabe-Kado, Yu Haranosono, Nobuo Kato, Yoshio Honma
Pages: 767-775
Published online on: 19 December 2012

  • View Full Article Download
Article

The microRNA-27a: ZBTB10-specificity protein pathway is involved in follicle stimulating hormone-induced VEGF, Cox2 and survivin expression in ovarian epithelial cancer cells

Yunli Lai, Xuerong Zhang, Zhenbo Zhang, Yuyan Shu, Xiaoling Luo, Yongbin Yang, Xiaojie Wang, Guoping Yang, Linxia Li, Youji Feng
Pages: 776-784
Published online on: 18 December 2012

  • View Full Article Download
Journal Cover
January-2026 Volume 68 Issue 1

Full Size Image

Cover Legend PDF

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

  • View Full Article Download
Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

  • View Full Article Download
Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

  • View Full Article Download
Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

  • View Full Article Download
Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

  • View Full Article Download
Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

  • View Full Article Download
Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

  • View Full Article Download
Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

  • View Full Article Download
Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

  • View Full Article Download
Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

  • View Full Article Download
Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

  • View Full Article Download
Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

  • View Full Article Download
Journal Cover
February-2026 Volume 68 Issue 2

Full Size Image

Cover Legend PDF

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

  • Download
Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

  • Download
Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

  • Purchase Download
Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

  • Download
Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

  • Download
Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

  • Download
Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

  • Download
Select a topic from the Information tab...
Special issues coming soon...
No data
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team