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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
February 2012 Volume 3 Issue 2

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Impact Factor: 2.3

Article Open Access

Inhibitory effect of endostatin combined with paclitaxel‑cisplatin on breast cancer in xenograft-bearing mice

Jianguo Sun, Li Deng, Yuzhong Duan, Fanglin Chen, Xinxin Wang, Dezhi Li, Zhengtang Chen
Pages: 159-164
Published online on: 18 November 2011

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Article

Osteogenic differences in cultured rat periosteal cells under hypoxic and normal conditions

Takehiro Ichijima, Kenichi Matsuzaka, Morio Tonogi, Gen-Yuki Yamane, Takashi Inoue
Pages: 165-170
Published online on: 28 November 2011

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Article

Cryotherapy is associated with improved clinical outcomes of sorafenib for the treatment of advanced hepatocellular carcinoma

Yongping Yang, Yinying Lu, Chunping Wang, Wenlin Bai, Jianhui Qu, Yan  Chen, Xiujuan Chang, Linjing An, Lin Zhou, Zhen Zeng, Min Lou, Jiyun Lv
Pages: 171-180
Published online on: 01 December 2011

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Article

Knockdown of vascular endothelial cell growth factor expression sensitizes U251 glioma cells to liposomal paclitaxel and radiation treatment in vitro

Yang Yu, Jianguo Feng, Xiangyun Zong, Hongjian Yang, Dehong Zou, Xiangming He
Pages: 181-186
Published online on: 11 November 2011

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Article

Antitumor effect of microbubbles enhanced by low frequency ultrasound cavitation on prostate carcinoma xenografts in nude mice

Yu Wang, Bing Hu, Xuehong Diao, Jizhen Zhang
Pages: 187-191
Published online on: 07 November 2011

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Article

Increased susceptibility to ischemia-induced ventricular tachyarrhythmias in depressed rats: Involvement of reduction of connexin 43

Wei Wu, Yan Li, Zhibing Lu, Xiaorong Hu
Pages: 192-194
Published online on: 30 November 2011

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Article

Subcellular location of antitumor tripeptide-tyroserleutide in human hepatocellular carcinoma cells

Xu Jian, Zheng Fu, Yanling Zhang, Xuchun Che, Rong Lu, Zhi Yao
Pages: 195-199
Published online on: 01 December 2011

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Article

Two IL28B polymorphisms are associated with the treatment response of different genotypes of hepatitis C in different racial populations: A meta-analysis

Li-Sheng Wu, Hong Wang, Xiao-Ping Geng
Pages: 200-206
Published online on: 21 November 2011

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Article

Erlotinib has better efficacy than gefitinib in adenocarcinoma patients without EGFR-activating mutations, but similar efficacy in patients with EGFR-activating mutations

Wen-Shuo Wu, Yuh-Min Chen, Chun-Ming Tsai, Jen-Fu Shih, Chao-Hua Chiu, Kun‑Ta  Chou, Shinn-Liang Lai, Chieh-Hung Wu, Yung-Hung Luo, Chu‑Yun  Huang, Yu-Chin Lee, Reury-Perng Perng, Jacqueline Whang-Peng
Pages: 207-213
Published online on: 16 November 2011

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Article

Microwave coagulation using a perfusion microwave electrode: Preliminary experimental study using ex vivo and in vivo liver

Hideto Umehara, Toshihito Seki, Ryosuke Inokuchi, Toru Tamai, Rinako  Kawamura, Toshiki Asayama, Kozo Ikeda, Kazuichi Okazaki
Pages: 214-220
Published online on: 11 November 2011

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Article

Monthly intravesical bacillus Calmette-Guérin maintenance therapy for non-muscle-invasive bladder cancer: 10-year experience in a single institute

Koo Han Yoo, Tae Joon Lim, Sung-Goo Chang
Pages: 221-225
Published online on: 01 December 2011

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Article

Concurrent use of Sr-89 chloride with zoledronic acid is safe and effective for breast cancer patients with painful bone metastases

Kimito Yamada, Mana Yoshimura, Hiroshi Kaise, Akihiko Ogata, Naoko Ueda, Koichi Tokuuye, Norio Kohno
Pages: 226-230
Published online on: 02 December 2011

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Article

Influence of interleukin-8 (IL-8) and IL-8 receptors on the migration of human keratinocytes, the role of PLC-γ and potential clinical implications

Wen G. Jiang, Andrew J. Sanders, Fiona Ruge, Keith G. Harding
Pages: 231-236
Published online on: 01 December 2011

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Article

Investigation of FJ 194940.1 gene alternative splicing in colon cancer and its association with clinicopathological parameters

Malwina Bartczak-Tomczyk, Aleksandra Sałagacka, Marek Mirowski, Ewa Balcerczak
Pages: 237-242
Published online on: 09 November 2011

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Article

Multidetector-computed tomography attenuation values between the tumor and aortic wall in response to induction therapy for esophageal cancer and its predictive value for aortic invasion

Hironori Tsujimoto, Takashi Ichikura, Satoshi Aiko, Yoshihisa Yaguchi, Isao Kumano, Risa Takahata, Yusuke Matsumoto, Kazumichi Yoshida, Satoshi Ono, Junji Yamamoto, Kazuo Hase
Pages: 243-248
Published online on: 22 November 2011

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Article

Effects of quercetin on apoptosis, NF-κB and NOS gene expression in renal ischemia/reperfusion injury

M. Kenan Kinaci, Nilufer Erkasap, Aysegul Kucuk, Tulay Koken, Murat Tosun
Pages: 249-254
Published online on: 16 November 2011

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Article

Increase of the therapeutic effect on non-small‑cell lung cancer cells with combination treatment of shRNA against Cyclin D1 and Bcl-xL in vitro

Ying Chen, Yong Cao, Danlei Yang, Kaiyan Li, Zhengyun Wang, Jing Zhu, Hansvin Bunjhoo, Shengdao Xiong, Yongjian Xu, Weining Xiong
Pages: 255-260
Published online on: 16 November 2011

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Article

Association between cytochrome P450 promoter polymorphisms and ischemic stroke

Su Kang Kim, Sung-Vin Yim, Byung-Cheol Lee
Pages: 261-268
Published online on: 22 November 2011

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Article

Steady and fluctuant methods of inhibition of acetylcholinesterase differentially regulate neurotrophic factors in the hippocampus of juvenile mice

Chong Li, Tian Wang, Na Jiang, Pengfei Yu, Yuan Du, Rutong Ren, Fenghua Fu
Pages: 269-272
Published online on: 28 November 2011

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Article

Use of a novel sonosensitizer in sonodynamic therapy of U251 glioma cells in vitro

Zhiqiang Chen, Jianhua Li, Xueming Song, Zhi Wang, Wu Yue
Pages: 273-278
Published online on: 25 November 2011

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Article

Magnetic fluid hyperthermia induced by radiofrequency capacitive field for the treatment of transplanted subcutaneous tumors in rats

Xu-Hong Li, Peng-Fei Rong, He-Kun Jin, Wei Wang, Jin-Tian Tang
Pages: 279-284
Published online on: 30 November 2011

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Article

Characterization of diethylnitrosamine-induced liver carcinogenesis in Syrian golden hamsters

Guo Chen, Zhi-Kai Dai, Rong-Gan Liang, Sheng-Jun Xiao, Song-Qing He, Hai-Lu Zhao, Qing Xu
Pages: 285-292
Published online on: 02 December 2011

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Article

Repair of meniscal defect using an induced myoblast-loaded polyglycolic acid mesh in a canine model

Yanglin Gu, Wenhui Zhu, Yuedong Hao, Liangyu Lu, Yang Chen, Yubin Wang
Pages: 293-298
Published online on: 01 December 2011

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Article

Improved radiosensitizing effect of the combination of etanidazole and paclitaxel for hepatocellular carcinoma in vivo

Yanling Yang, Cheng Jin, Haimin Li, Yong He, Zhaohui Liu, Ling Bai, Kefeng Dou
Pages: 299-303
Published online on: 24 November 2011

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Article

Long-term follow-up of localized, primary gastric diffuse large B-cell lymphoma treated with rituximab and CHOP

Yujin Kobayashi, Yoshihiro Hatta, Atsuko Hojo, Yoshimasa Kura, Yoshihito  Uchino, Hiromichi Takahashi, Satomi Kiso, Yukio Hirabayashi, Mai Yagi, Hitomi  Kodaira, Daisuke Kurita, Toshitake Tanaka, Katsuhiro Miura, Noriyoshi Iriyama, Sumiko Kobayashi, Umihiko Sawada, Masahiko Sugitani, Jin Takeuchi
Pages: 304-308
Published online on: 22 November 2011

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Article

Association of SLC38A4 and system A with abnormal fetal birth weight

Zhen Li, Guangrui Lai, Lijun Deng, Yue Han, Danfeng Zheng, Weiwei Song
Pages: 309-313
Published online on: 28 November 2011

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Article

Dan-Shen-Yin protects the heart against inflammation and oxidative stress induced by acute ischemic myocardial injury in rats

Kui-Po Yan, Yong Guo, Zhihua Xing, Xi Huang, Shengping Dai, Min Duan, Xinhua Sun, Wei Huang, Weijun Peng
Pages: 314-318
Published online on: 05 December 2011

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Article

Enhanced antitumor effects of a dendritic cell vaccine transfected with gastric cancer cell total RNA carrying the 4-1BBL gene in vitro

Zhenchuan Song, Chenjun Guo, Yong Li, Bibo Tan, Liqiao Fan, Jianwei Xiao
Pages: 319-323
Published online on: 28 November 2011

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Article

miR-196a2 polymorphisms and susceptibility to cancer: A meta-analysis involving 24,697 subjects

Pingyu Wang, Shuyang Xie, Aidong Cui, Yanxiang Zhang, Baofa Jiang
Pages: 324-330
Published online on: 01 December 2011

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Article

Elevated thymidine kinase 1 in serum following neoadjuvant chemotherapy predicts poor outcome for patients with locally advanced breast cancer

Zhi-Heng Huang, Xing-Song Tian, Rong Li, Xian-Ming Wang, Wen Wen, Hong Guan, Ya-Jie Yang
Pages: 331-335
Published online on: 28 November 2011

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Article

Bladder cancer-associated protein is suppressed in human cervical tumors

Min Peng, Tingbo Xie, Juan Yu, Bin Xu, Qibin Song, Xinxing Wu
Pages: 336-340
Published online on: 05 December 2011

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Article

Expression of mitotic-arrest deficiency 2 predicts the efficacy of neoadjuvant chemotherapy for locally advanced uterine cervical cancer

Masanari Morishita, Toshiyuki Sumi, Yusuke Nakano, Masatomo Teramae, Takeshi Fukuda, Hiroyuki Nobeyama, Hiroyuki Yoshida, Yoshinari Matsumoto, Tomoyo Yasui, Osamu Ishiko
Pages: 341-346
Published online on: 05 December 2011

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Article Open Access

Administration of anti-vascular endothelial growth factor antibody following hepatectomy does not inhibit remnant liver regeneration or growth of remnant metastases

Kazuhiko Kasuya, Minako Suzuki, Yuichi Nagakawa, Yoshiaki Suzuki, Satoru Kikuchi, Bunso Kyo, Takaaki Matsudo, Takao Itoi, Akihiko Tsuchida, Tatsuya Aoki
Pages: 347-350
Published online on: 06 December 2011

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Article

miRNA expression profile in primary gastric cancers and paired lymph node metastases indicates that miR-10a plays a role in metastasis from primary gastric cancer to lymph nodes

Weidong Chen, Zhaoqing Tang, Yihong Sun, Youyou Zhang, Xuefei Wang, Zhenbin Shen, Fenglin Liu, Xinyu Qin
Pages: 351-356
Published online on: 06 December 2011

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Article

γ-secretase inhibition combined with cisplatin enhances apoptosis of nasopharyngeal carcinoma cells

Jun-Xu Zhou, Ji-Bo Han, Shi-Ming Chen, Yu Xu, Yong-Gang Kong, Bo-Kui Xiao, Ze-Zhang Tao
Pages: 357-361
Published online on: 06 December 2011

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Journal Cover
May-2026 Volume 31 Issue 5

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Impact Factor: 2.3

Review Open Access

FCER1G: A multifunctional regulator in the immune microenvironment (Review)

Yuyu Zhang, Jinglan Wang, Wenting He, Tao Liu
Article Number: 146
Published online on: 26 March 2026

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Article Open Access

A nomogram for predicting recurrence‑free survival in patients with high‑risk GIST receiving adjuvant imatinib: A nationwide registry study

Chun-Nan Yeh, Yan-Shen Shan, Ching-Yao Yang, Chin-Fu Hsiao, Chung-Hsin Tsai, Chuan-Cheng Wang, Ming-Tsan Lin, Chun-Fu Ting, De-Chuan Chan, Te-Hung Chen, Chueh-Chuan Yen, Yen-Yang Chen, Hsuan-Yu Lin, Ta-Sen Yeh, Ching-Liang Ho, Tze-Yu Shieh, Li-Yaun Bai, Jun-Te Hsu, I-Shu Chen, Li-Tzong Chen, Hui-Jen Tsai, The Taiwan Cooperative Oncology Group Gist Study Group
Article Number: 145
Published online on: 24 March 2026

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[Retracted] MicroRNA‑18a‑5p represses scar fibroblast proliferation and extracellular matrix deposition through regulating Smad2 expression

Tianshi Li, Yiguang Wu, Dandan Liu, Lida Zhuang
Article Number: 144
Published online on: 23 March 2026

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Article

Risk factors for severe retinopathy of prematurity: A retrospective case‑control study

Qingmin Ma, Xi Lv, Jiangya Wang, Kejun Li, Wenwen Τang
Article Number: 143
Published online on: 20 March 2026

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Atorvastatin augments collateral formation and functional recovery after indirect revascularization in adult ischemic moyamoya disease: A randomized trial

Dawei Wang, Jingya Dai, Shumei Li, Yaping Liu, Xiaofeng Xing, Lei Huang, Qijun Pang
Article Number: 142
Published online on: 19 March 2026

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Maresin 1 activates autophagy through SIRT1/PPAR‑γ signaling to mitigate high glucose‑induced pyroptosis in human retinal pigment epithelial cells

Jun Zhang, Ding Zhao, Yuanqing Zhang, Haoxiang Sun, Zhipeng Yan, Haiyan Sun
Article Number: 141
Published online on: 19 March 2026

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Review Open Access

Advances in new ultrasound technologies in targeted prostate biopsy (Review)

Tingting Jin, Liying Wang, Shusen Zheng
Article Number: 140
Published online on: 19 March 2026

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Review Open Access

Immune cross talk and therapeutic advances in lactate metabolism in the tumor microenvironment (Review)

Min Liu, Kui Su
Article Number: 139
Published online on: 19 March 2026

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Article Open Access

Immunohistochemical evaluation of gastric‑type markers in primary extramammary Paget disease: Differential MUC5AC expression between in situ and invasive lesions

Naoto Kohno, Mitsuaki Ishida, Shizuka Ono, Yoshinobu Hirose
Article Number: 138
Published online on: 19 March 2026

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Disrupted beginnings: Neurodevelopmental outcomes of COVID‑19 lockdowns in early childhood (Review)

Ioanna Giannopoulou, Vasiliki Efstathiou, Maria-Ioanna Stefanou, Panagiota Korkoliakou, James N. Tsoporis, Demetrios A. Spandidos, Emmanouil Rizos
Article Number: 137
Published online on: 16 March 2026

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Retraction Open Access

[Retracted] Icariin inhibits oral squamous cell carcinoma cell proliferation and induces apoptosis via inhibiting the NF‑κB and PI3K/AKT pathways

Ling Sun, Jing Zhang
Article Number: 136
Published online on: 16 March 2026

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Effects of fullerenol C60 on the liver, heart and brain tissues of streptozotocin‑induced diabetic rats with sepsis

Necmiye Şengel, Ömer Kubat, Laman Farajsoylu, Ahmet Çağri Büyükkasap, Muharrem Atli, Şaban Cem Sezen, Hasan Bostanci, Kürşat Dikmen, Işin Güneş, Fatma Er, Mustafa Kavutçu, Mustafa Arslan
Article Number: 135
Published online on: 13 March 2026

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Long non‑coding RNA KCNQ1OT1 promotes ovarian cancer cell malignant characteristics by targeting the miR‑140‑5p/KLK10 axis

Renjie Duan, Zhenyu Tao, Shun Tao, Aichen Yang, Xu Yang, Changzheng Li, Xiaoxiang Zhu, Kexin Zhang, Zhuofu Li, Shanjun Tao
Article Number: 134
Published online on: 11 March 2026

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Article

Deciphering the dynamics of the splenium: A comprehensive analysis of flair hyperintensity variations

Ezel Yaltirik Bilgin, Özkan Ünal, Yasin Özdemir, Onur Şimşek
Article Number: 133
Published online on: 09 March 2026

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Prior curative‑intent treatment strategy affects progression outcomes of first‑line immunotherapy in metastatic non‑small cell lung cancer: A retrospective cohort study

Ruhper Cekin, Didar Senocak, Serdar Arici, Alpaslan Ozgun
Article Number: 132
Published online on: 09 March 2026

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[Retracted] Recent perspectives of electronic medical record systems (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 131
Published online on: 09 March 2026

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Case Report Open Access

Direct venous‑to‑arterial communication as a novel mechanism for ectopic embolism following esophageal variceal embolization: A case report

Youchun Lei, You Ke, Tianwen Yang, Zhengguo Xu
Article Number: 130
Published online on: 06 March 2026

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Case Report

Diagnostic and therapeutic challenges of isolated spinal vasculitis: A case report

Yajun Yao, Ge-Hong Dong, De-Cai Tian
Article Number: 129
Published online on: 06 March 2026

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Article Open Access

Impact of older age on prognosis in hypersensitivity pneumonitis: A systematic review and meta‑analysis

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Vasiliki Therapioti‑Mavroudi, Nikolaos Trakas, Eleni Sklapani, Demetrios A. Spandidos, Alexandru Corlateanu, Vasiliki Epameinondas Georgakopoulou
Article Number: 128
Published online on: 06 March 2026

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Article

Anti‑inflammatory effects of oridonin on an in vitro model using LPS‑treated human intestinal Caco‑2 cells

Maonan Wang, Bo Xu, Linyue Li, Yu Wang, Mingcheng Li
Article Number: 127
Published online on: 03 March 2026

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Case Report

Management after two consecutive suction losses during small‑incision lenticule extraction: A case report

Luanying Wei, Tiantian Qi, Nan Li, Qiang Shi, Shengjian Mi, Cheng Pei
Article Number: 126
Published online on: 03 March 2026

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Case Report Open Access

Hematemesis resulting from mesenteric venous thrombosis: A case report

Chunyu Shi, Zhongmin Li, Lu Pan, Bin Song
Article Number: 125
Published online on: 02 March 2026

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Article

Inhibitory effects of spermidine on lipopolysaccharide‑induced inflammation in RAW 264.7 cells

Hao Yuan, Fang Peng, Yi-Feng Zhou, Si-Xian Wu, Zhen-Yi Long, Ya-Meng Peng, Yi-Zhao Zhou
Article Number: 124
Published online on: 02 March 2026

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Retraction Open Access

[Retracted] Telemedicine in clinical setting (Review)

Xiao-Ying Zhang, Peiying Zhang
Article Number: 123
Published online on: 02 March 2026

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Article

Effects of spironolactone on cytotoxic damage in osteoblasts

So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Article Number: 122
Published online on: 27 February 2026

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Article Open Access

RNU2‑1 gene copy number variations do not affect serum levels of miR‑1246 as a biomarker for lung adenocarcinoma

Makiko Ueda, Shinya Sato, Yohei Miyagi, Toshiko Aiso
Article Number: 121
Published online on: 27 February 2026

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Article Open Access

A laboratory micro‑CT technique is useful to visualize and characterize dermal skin components in a 3D manner

Katarina Lundqvist, Hanna Tufvesson, Lars B. Dahlin, Marius Reichardt, Bodil Ohlsson
Article Number: 120
Published online on: 27 February 2026

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Case Report

A rare case of early‑onset cerebral syphilitic gummata with severe neurological decline in early‑stage syphilis: A case report

Yujie Ji, Shelin Liu, Yunwei Wang, Youcai Zhao, Zheng Cai, Bing Li
Article Number: 119
Published online on: 26 February 2026

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Review Open Access

Organelle homeostasis disruption: A driving force in the progression of cardiomyopathy (Review)

Yuxing Hou, Chao Li, Youyou Chen, Danfeng Zhong, Miaomiao Chai, Lijiao Mo, Senna Lin, Fangfang Huang, Qi Chen
Article Number: 118
Published online on: 26 February 2026

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June-2026 Volume 31 Issue 6

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Impact Factor: 2.3

Article Open Access

Multi‑omics analysis of glutamine and fish collagen peptides in alleviating post‑antibiotic Streptococcus pneumoniae injury in feline lung cells

Huasong Bai, Tong Liu, Hengyan Wang, Hongchen Jin, Yunliang Li, Zhanzhong Wang
Article Number: 148
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] MicroRNA‑1236‑3p/translationally controlled tumor protein (TPT1) axis participates in congenital hypothyroidism progression by regulating neuronal apoptosis

Tingting Meng, Shiman Shen, Cheng Li, Xuehua Liu
Article Number: 147
Published online on: 30 March 2026

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