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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2006 Volume 17 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Chemokines in vascular pathology (Review)

Stavros Apostolakis, Emmanouil G. Papadakis, ELias Krambovitis, Demetrios A. Spandidos
Pages: 691-701
Published online on: 01 May 2006

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Article

Protein phosphatase 2A interacts with Chk2 and regulates phosphorylation at Thr-68 after cisplatin treatment of human ovarian cancer cells

Xiaobing Liang, Eddie Reed, Jing Jie Yu
Pages: 703-708
Published online on: 01 May 2006

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Article

Identification and localization of adrenomedullin-storing cardiac mast cells

Anna S. Belloni, Lucia Petrelli, Diego Guidolin, Renzo De Toni, Sergio Bova, Raffaella Spinazzi, Gino Gerosa, Gian Paolo Rossi, Gastone G. Nussdorfer
Pages: 709-713
Published online on: 01 May 2006

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Article

E2F-1 is a critical modulator of cellular senescence in human cancer

Chaehwa Park, Inkyoung Lee, Won Ki Kang
Pages: 715-720
Published online on: 01 May 2006

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Article

Efficient differentiation into skin cells of bone marrow cells recovered in a pellet after density gradient fractionation

Reinhold J. Medina, Ken Kataoka, Masahiro Miyazaki, Nam-Ho Huh
Pages: 721-727
Published online on: 01 May 2006

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Article

Non-muscle myosin heavy chain IIA and IIB interact and co-localize in living cells: Relevance for MYH9-related disease

Monica Marini, Maurizio Bruschi, Alessandro Pecci, Roberta Romagnoli, Luca Musante, Giovanni Candiano, Gian Marco Ghiggeri, Carlo Balduini, Marco Seri, Roberto Ravazzolo
Pages: 729-736
Published online on: 01 May 2006

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Article

Development and evaluation of a colorimetric membrane-array method for the detection of circulating tumor cells in the peripheral blood of Taiwanese patients with colorectal cancer

Jaw-Yuan Wang, Ching-Sheng Yeh, Yi-Fang Chen, Chan-Hang Wu, Jan-Sing Hsieh, Tsung-Jan Huang, Sung-Yu Huang, Shiu-Ru Lin
Pages: 737-747
Published online on: 01 May 2006

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Article

Human RAB24, interestingly and predominantly distributed in the nuclei of COS-7 cells, is colocalized with cyclophilin A and GABARAP

Maoqing Wu, Gang Yin, Xin Zhao, Chaoneng Ji, Shaohua Gu, Rong Tang, Hai Dong, Yi Xie, Yumin Mao
Pages: 749-754
Published online on: 01 May 2006

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Article

Mutation in exon 7 of PTCH deregulates SHH/PTCH/SMO signaling: Possible linkage to WNT

Vesna Musani, Philippe Gorry, Aleksandra Basta-Juzbasic, Tonci Stipic, Pavle Miklic, Sonja Levanat
Pages: 755-759
Published online on: 01 May 2006

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Article

Yes-associated protein (YAP65) in relation to Smad7 expression in human pancreatic ductal adenocarcinoma

Junchao Guo, Jörg Kleeff, Yupei Zhao, Junsheng Li, Thomas Giese, Irene Esposito, Markus W. Büchler, Murray Korc, Helmut Friess
Pages: 761-767
Published online on: 01 May 2006

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Article

Genomic abnormalities in chronic lymphocytic leukemia influence gene expression by a gene dosage effect

John D. Dickinson, Avadhut Joshi, Javeed Iqbal, Warren Sanger, Philip J. Bierman, Shantaram S. Joshi
Pages: 769-778
Published online on: 01 May 2006

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Article

The calcium-sensing receptor and vitamin D receptor expression in tertiary hyperparathyroidism

Tomasz Grzela, Witold Chudzinski, Zofia Lasiecka, Justyna Niderla, Grzegorz Wilczynski, Barbara Gornicka, Aleksander Wasiutynski, Magdalena Durlik, Anna Boszczyk, Robert Brawura-Biskupski-Samaha, Piotr Dziunycz, Lukasz Milewski, Marta Lazarczyk, Maciej Lazarczyk, Ireneusz Nawrot
Pages: 779-783
Published online on: 01 May 2006

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Article

Quantitative evaluation of partial deletions of the DAZ gene cluster

G. Letizia D'Amico, Daniela Di Benedetto, Franca M. Pezzino, Vincenza Giuffrida, Massimo Libra, Marco Fichera, Grazia Mauceri, Giancarlo Rappazzo, Rosario D'Agata, Enzo Vicari, Salvatore Travali, Aldo E. Calogero
Pages: 785-789
Published online on: 01 May 2006

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Article

Polymorphism in ABCA1 influences CSF 24S-hydroxycholesterol levels but is not a major risk factor of Alzheimer's disease

Heike Kölsch, Dieter Lütjohann, Frank Jessen, Klaus Von Bergmann, Sandra Schmitz, Horst Urbach, Wolfgang Maier, Reinhard Heun
Pages: 791-794
Published online on: 01 May 2006

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Article

CER1 is a common target of WNT and NODAL signaling pathways in human embryonic stem cells

Masuko Katoh, Masaru Katoh
Pages: 795-799
Published online on: 01 May 2006

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Article

Gene transduction of tristetraprolin or its active domain reduces TNF-α production by Jurkat T cells

Eiji Suzuki, Akito Tsutsumi, Daisuke Goto, Isao Matsumoto, Satoshi Ito, Makoto Otsu, Masafumi Onodera, Satoru Takahashi, Yukio Sato, Takayuki Sumida
Pages: 801-809
Published online on: 01 May 2006

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Article

Anandamide-induced apoptosis in Chang liver cells involves ceramide and JNK/AP-1 pathway

Michela Giuliano, Giuseppe Calvaruso, Ornella Pellerito, Patrizia Portanova, Daniela Carlisi, Renza Vento, Giovanni Tesoriere
Pages: 811-819
Published online on: 01 May 2006

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Article

Apolipoprotein-E modulates the cytotoxic effect of β-amyloid on rat brain endothelium in an isoform-dependent specific manner

Marcella Folin, Silvia Baiguera, Diego Guidolin, Rosa Di Liddo, Claudio Grandi, Eugenio De Carlo, Gastone G. Nussdorfer, Pier Paolo Parnigotto
Pages: 821-826
Published online on: 01 May 2006

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Article

Antibody to hepatitis B core antigen is associated with the development of hepatocellular carcinoma in hepatitis C virus-infected persons: A 12-year prospective study

Kazuo Tanaka, Yumiko Nagao, Tatsuya Ide, Ryukichi Kumashiro, Michio Sata
Pages: 827-832
Published online on: 01 May 2006

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Article

Synthetic peptide F2A4-K-NS mimics fibroblast growth factor-2 in vitro and is angiogenic in vivo

X. Lin, K. Takahashi, S. L. Campion, Y. Liu, G. G. Gustavsen, L. A. Peña, P. O. Zamora
Pages: 833-839
Published online on: 01 May 2006

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Article

Caspase-1 as a radio- and chemo-sensitiser in vitro and in vivo

Pilar Martín-Duque, Miguel Quintanilla, Iain McNeish, Rita Lopes, Jesús Romero, Diana Romero, Nick R. Lemoine, Santiago Ramón y Cajal, Georges Vassaux
Pages: 841-847
Published online on: 01 May 2006

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Article

Identification of a unique set of genes altered during cell-cell contact in an in vitro model of prostate cancer bone metastasis

Jun Wang, Anait S. Levenson, Robert L. Satcher
Pages: 849-856
Published online on: 01 May 2006

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Article

Relationship between the proliferative capability of hepatocytes and the intrahepatic expression of hepatocyte growth factor and c-Met in the course of cirrhosis development in rats

Hideyuki Inoue, Fumi Yokoyama, Yuko Kita, Hitoshi Yoshiji, Tatsuhiro Tsujimoto, Akihiro Deguchi, Seiji Nakai, Asahiro Morishita, Naohito Uchida, Tsutomu Masaki, Seishiro Watanabe, Shigeki Kuriyama
Pages: 857-864
Published online on: 01 May 2006

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Article

Accumulation of steroidogenic acute regulatory protein mRNA, and decrease in the secretory and proliferative activity of rat adrenocortical cells in the presence of proteasome inhibitors

Agnieska Ziolkowska, Cinzia Tortorella, Gastone G. Nussdorfer, Marcin Rucinski, Mariola Majchrzak, Ludwik K. Malendowicz
Pages: 865-868
Published online on: 01 May 2006

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Article

Deletion of the kinase domain from death-associated protein kinase enhances spatial memory in mice

Kazunori Yukawa, Tetsuji Tanaka, Tao Bai, Li Li, Yuji Tsubota, Kyoko Owada-Makabe, Masanobu Maeda, Katsuaki Hoshino, Shizuo Akira, Hiroyuki Iso
Pages: 869-873
Published online on: 01 May 2006

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Article

Increased expression of membrane TNF-α on activated peripheral CD8+ T cells in systemic lupus erythematosus

Takahiko Horiuchi, Chika Morita, Hiroshi Tsukamoto, Hiroki Mitoma, Takuya Sawabe, Shin-Ichi Harashima, Yoichiro Kashiwagi, Seiichi Okamura
Pages: 875-879
Published online on: 01 May 2006

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Article

Serum cytokine concentrations and acute graft-versus-host disease after allogeneic peripheral blood stem cell transplantation: Concurrent measurement of ten cytokines and their respective ratios using cytometric bead array

Nobuharu Fujii, Akio Hiraki, Keisuke Aoe, Tomoyuki Murakami, Kazuma Ikeda, Kozo Masuda, Keitaro Matsuo, Katsuji Shinagawa, Fumihiko Ishimaru, Kazuro Sugi, Zbigniew Darzynkiewicz, Mitsune Tanimoto
Pages: 881-885
Published online on: 01 May 2006

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Article

Tumour necrosis factor-α: prognostic role and relationship with interleukin-8 and endothelin-1 in non-small cell lung cancer

Laura Boldrini, Silvia Gisfredi, Silvia Ursino, Marco Lucchi, Franca Melfi, Alfredo Mussi, Fulvio Basolo, Gabriella Fontanini
Pages: 887-892
Published online on: 01 May 2006

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Article

STI571 (Glivec) induces cell death in the gastrointestinal stromal tumor cell line, GIST-T1, via endoplasmic reticulum stress response

Hajime Nakatani, Keijiro Araki, Toufeng Jin, Michiya Kobayashi, Takeki Sugimoto, Toyokazu Akimori, Tsutomu Namikawa, Ken Okamoto, Takumi Nakano, Takehiro Okabayashi, Norihiro Hokimoto, Hiroyuki Kitagawa, Takahiro Taguchi
Pages: 893-897
Published online on: 01 May 2006

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Article

Amelioration of liver fibrogenesis by dual inhibition of PDGF and TGF-β with a combination of imatinib mesylate and ACE inhibitor in rats

Hitoshi Yoshiji, Shigeki Kuriyama, Ryuichi Noguchi, Yasuhide Ikenaka, Junichi Yoshii, Koji Yanase, Tadashi Namisaki, Mitsuteru Kitade, Masaharu Yamazaki, Kiyoshi Asada, Takemi Akahane, Tatsuhiro Tsujimoto, Masahito Uemura, Hiroshi Fukui
Pages: 899-904
Published online on: 01 May 2006

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Article

In vitro and in vivo immunomodulating activities of Shoyu polysaccharides from soy sauce

Hiroaki Matsushita, Makio Kobayashi, Ryo-Ichi Tsukiyama, Kenji Yamamoto
Pages: 905-909
Published online on: 01 May 2006

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Article

CD4+ T cells and the Th1/Th2 imbalance are implicated in the pathogenesis of Graves' ophthalmopathy

Ning Xia, Suxian Zhou, Yuzhen Liang, Changqing Xiao, Hanlei Shen, Hailin Pan, Hongming Deng, Naizun Wang, Qingdi Q. Li
Pages: 911-916
Published online on: 01 May 2006

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Article

Abnormal DNA end-joining activity in human head and neck cancer

Ki-Hyuk Shin, Mo K. Kang, Reuben H. Kim, Ayako Kameta, Marcel A. Baluda, No-Hee Park
Pages: 917-924
Published online on: 01 May 2006

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Article

Adrenomedullin binding protein-1 is downregulated during polymicrobial sepsis in the rat

Yingjie Cui, Youxin Ji, Rongqian Wu, Mian Zhou, Ping Wang
Pages: 925-929
Published online on: 01 May 2006

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Article

Apoptotic-inducing activity of novel polycyclic aromatic compounds in human leukemic cells

Kristin R. Landis-Piwowar, Di Chen, Qiuzhi Cindy Cui, Vesna Minic, Frederick F. Becker, Bimal K. Banik, Q. Ping Dou
Pages: 931-935
Published online on: 01 May 2006

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Article

Expression of pigment epithelial derived factor is reduced in non-small cell lung cancer and is linked to clinical outcome

Lijian Zhang, Jinfeng Chen, Yang Ke, Robert E. Mansel, Wen G. Jiang
Pages: 937-944
Published online on: 01 May 2006

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Article

Apoptotic activity of a novel synthetic cantharidin analogue on hepatoma cell lines

Stanton Hon Lung Kok, Chung Hin Chui, Wing Sze Lam, Jien Chen, Fung Yi Lau, Gregory Yin Ming Cheng, Raymond Siu Ming Wong, Paul Po San Lai, Thomas Wai Tong Leung, Johnny Cheuk On Tang, Albert Sun Chi Chan
Pages: 945-949
Published online on: 01 May 2006

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Article

Comparative integromics on BMP/GDF family

Yuriko Katoh, Masaru Katoh
Pages: 951-955
Published online on: 01 May 2006

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Article

Ethanol extract from Artemisia vestita, a traditional Tibetan medicine, exerts anti-sepsis action through down-regulating the MAPK and NF-κB pathways

Yang Sun, Yi-Hua Li, Xing-Xin Wu, Wei Zheng, Zong-Hui Guo, Yang Li, Ting Chen, Zi-Chun Hua, Qiang Xu
Pages: 957-962
Published online on: 01 May 2006

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis

Enbo Wang, Haixiang Zhang, Dechao Wu, Sadik Ali, Xianglu Ji
Article Number: 105
Published online on: 26 February 2026

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Review Open Access

mTOR signaling pathway in primary Sjögren's syndrome: Pathogenesis and potential therapeutic targets (Review)

Rongxiu Huo, Yanting Yang, Chengcheng Wei, Yang Yang, Danli Meng, Jinying Lin, Xinxiang Huang
Article Number: 104
Published online on: 25 February 2026

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Article Open Access

Bumetanide‑blocked SLC12A2 exerts a protective effect in experimental diabetic retinopathy

Yuting Zhang, Xiuli Wang, Qinyue Xie, Yue Huang, Dongjia Huang, Ziqing Liu, Tong Xu, Man Ni, Hongwei Yang
Article Number: 103
Published online on: 25 February 2026

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Article Open Access

Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 102
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] A novel role for Livin in the response to ultraviolet B radiation and pterygium development

Shuang-Qing Wu, Qi-Bin Xu, Wen-Yan Sheng, Lin-Ya Su, Li-Wei Zhu
Article Number: 101
Published online on: 24 February 2026

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Article Open Access

Endothelial UNC5B regulates blood‑retinal barrier homeostasis

Yujia Yao, Suyu Wang, Jiajun Li, Qianzi Jin, Ziyi Chen, Qin Jiang, Keran Li
Article Number: 100
Published online on: 20 February 2026

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Review Open Access

Metabolic hubs in reproduction: The regulatory network of lipid droplets in gamete and embryo physiology (Review)

Liuzhu Pan, Zongzhuang Wen, Yi Jin
Article Number: 99
Published online on: 17 February 2026

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Review Open Access

The role and mechanism of IL‑35 in myasthenia gravis (Review)

Jing Mao, Lin-Ming Zhang, Yan-Lin Zhu, Shu-Ji Gao, Ming-Wei Liu
Article Number: 98
Published online on: 17 February 2026

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Article Open Access

miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways

Jing Wang, Yujia Zou, Yani Wang, Zheming Yang, Daoshen Liu, Xiaolin Su, Haixu Song, Kai Xu, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 97
Published online on: 16 February 2026

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Review Open Access

Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review)

Yufei Zhong, Yunfei Zou, Zhuoyuan Yang, Junjun Wang, Zezheng Pan, Jiugeng Feng
Article Number: 96
Published online on: 16 February 2026

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Review Open Access

Microglia‑mediated neuroinflammation in intracerebral hemorrhage: Pathological mechanisms and implications for therapeutic development (Review)

Xuehui Fan, Changzhi Pu, Luyi Zhong, Oucheng Wang, Binyi Zhao, Dongyi Liao, Xue Bai, Guiquan Chen, Guoqiang Yang
Article Number: 95
Published online on: 16 February 2026

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Correction Open Access

[Corrigendum] Silencing of Rac1 modifies lung cancer cell migration, invasion and actin cytoskeleton rearrangements and enhances chemosensitivity to antitumor drugs

Qing-Yong Chen, Li-Qun Xu, De-Min Jiao, Qing-Hua Yao, Yan-Yi Wang, Hui-Zhen Hu, Yu-Quan Wu, Jia Song, Jie Yan, Li-Jun Wu
Article Number: 94
Published online on: 12 February 2026

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Article Open Access

Orcinol glucoside ameliorates pulmonary fibrosis by suppressing hyaluronic acid synthesis and macrophage M2 polarization via targeting hyaluronic acid synthase 2

Caizi Li, Xinglinzi Tang, Xiaoru Luo, Xin Lai, Jing Yang, Zheng Xu, Gulizeba Muhetaer, Yizi Xie, Xiufang Huang, Hang Li
Article Number: 93
Published online on: 10 February 2026

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Helicobacter pylori and hyperglycemia fuel gastric cancer glycolysis: Mechanisms and targeted intervention (Review)

Youjia Liu, Fang Wang, Ya Deng, Yanxia Hu, Feihong Shu, Jie Yu, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Qian Du, Jingyu Xu, Rui Xie
Article Number: 92
Published online on: 09 February 2026

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Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review)

Jingjing Wu, Siqi Zhang, Junjie Wu, Yuhang Luan, Xingchen Yao, Boyan Xu, Yiting Wang, Yingyue Sheng, Yuzheng Xue, Yilin Ren
Article Number: 91
Published online on: 09 February 2026

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Review Open Access

Chorus line in oral squamous cell carcinoma: How stromal and immune players orchestrate tumor progression (Review)

Eliano Cascardi, Mario Della Mura, Nicoletta Sgarro, Silvia Minei, Gerardo Cazzato, Eugenio Maiorano, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Fábio França Vieira E Silva, Eleonora Lo Muzio, Mario Dioguardi, Andrea Ballini
Article Number: 90
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature 

Xijuan Liu, Chen Yan, Xueqiang Deng, Jingyu Jia
Article Number: 89
Published online on: 09 February 2026

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Review Open Access

Post‑translational modifications in diabetic kidney disease (Review)

Mengfei He, Zihang Wang, Zhuang Miao, Yu Zhao, Lingling Wei, Lijie Zhang, Ruili Yin, Yan Wang, Longyan Yang
Article Number: 88
Published online on: 09 February 2026

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Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Review Open Access

Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Review Open Access

Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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Review Open Access

IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Correction Open Access

[Corrigendum] Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling  

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang
Article Number: 118
Published online on: 09 March 2026

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Article Open Access

HELLS inhibits autophagy‑dependent ferroptosis in nasopharyngeal carcinoma by modulating the Nrf2/HO‑1/GPX4 pathway

Chengxun Jin, Jinqiu Li, Siqi Han, Chaoluomeng Bai, Jingpu Yang, Zonggui Wang
Article Number: 117
Published online on: 09 March 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis

Ying Zhang, Hong Cao, Yue-Yue Hu, Hua Wang, Chang-Jun Zhang
Article Number: 116
Published online on: 09 March 2026

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Article Open Access

Propofol upregulates MFG‑E8 in BV2 cells to inhibit pyroptosis mediated by the NF‑κB/NLRP3 pathway, thereby ameliorating ischemic‑reperfusion neuronal injury

Shewei Guo, Yingwei Zhen, Guosheng Zhou, Zhihua Zhao
Article Number: 115
Published online on: 05 March 2026

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Article Open Access

Exosomal circ0000549 promotes MNNG‑induced gastric cancer through miR‑15b‑5p/KIF1B

Zhaofeng Liang, Zihan Gao, Yue Zhang, Jiajia Song, Hui Qian, Xuezhong Xu
Article Number: 114
Published online on: 04 March 2026

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Expression of Concern Open Access

[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy  

Fangfang Li, Ning Zhang, Qingqing Wu, Yuan Yuan, Zheng Yang, Mengqiao Zhou, Jinxiu Zhu, Qizhu Tang
Article Number: 113
Published online on: 04 March 2026

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Review Open Access

Treatment of pulmonary fibrosis: From disease mechanisms to future novel therapies (Review)

Sen Lu, Yunfei Liu, Xiaohua Li, Qipeng Yao
Article Number: 112
Published online on: 03 March 2026

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Review Open Access

Research progress in single‑cell omics technologies for kidney disease (Review)

Jia Xu, Ziwei Chen, Shengyao Li, Xiaoya Wang, Ming Chen
Article Number: 111
Published online on: 03 March 2026

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Review Open Access

CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review)

Xiuping Lai, Yan Yan, Lu Sun, Zili Lei, Yanhong Yang
Article Number: 110
Published online on: 03 March 2026

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Review Open Access

Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)

Sen Lu, Jiale Tong, Jing Jiang, Qin Zhang, Youjin Huang
Article Number: 109
Published online on: 03 March 2026

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Review Open Access

The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)

Yingying Zhang, Ruxin Shen
Article Number: 108
Published online on: 02 March 2026

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Review Open Access

Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

Bojiao Yang, Feng Li, Guimao Cao, Mingtu Nuo, Yaxin Shi, Zilu Wang, Jing Jia, Wei Shi, Zhiyong Liu
Article Number: 107
Published online on: 02 March 2026

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Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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