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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2006 Volume 17 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Chemokines in vascular pathology (Review)

Stavros Apostolakis, Emmanouil G. Papadakis, ELias Krambovitis, Demetrios A. Spandidos
Pages: 691-701
Published online on: 01 May 2006

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Article

Protein phosphatase 2A interacts with Chk2 and regulates phosphorylation at Thr-68 after cisplatin treatment of human ovarian cancer cells

Xiaobing Liang, Eddie Reed, Jing Jie Yu
Pages: 703-708
Published online on: 01 May 2006

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Article

Identification and localization of adrenomedullin-storing cardiac mast cells

Anna S. Belloni, Lucia Petrelli, Diego Guidolin, Renzo De Toni, Sergio Bova, Raffaella Spinazzi, Gino Gerosa, Gian Paolo Rossi, Gastone G. Nussdorfer
Pages: 709-713
Published online on: 01 May 2006

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Article

E2F-1 is a critical modulator of cellular senescence in human cancer

Chaehwa Park, Inkyoung Lee, Won Ki Kang
Pages: 715-720
Published online on: 01 May 2006

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Article

Efficient differentiation into skin cells of bone marrow cells recovered in a pellet after density gradient fractionation

Reinhold J. Medina, Ken Kataoka, Masahiro Miyazaki, Nam-Ho Huh
Pages: 721-727
Published online on: 01 May 2006

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Article

Non-muscle myosin heavy chain IIA and IIB interact and co-localize in living cells: Relevance for MYH9-related disease

Monica Marini, Maurizio Bruschi, Alessandro Pecci, Roberta Romagnoli, Luca Musante, Giovanni Candiano, Gian Marco Ghiggeri, Carlo Balduini, Marco Seri, Roberto Ravazzolo
Pages: 729-736
Published online on: 01 May 2006

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Article

Development and evaluation of a colorimetric membrane-array method for the detection of circulating tumor cells in the peripheral blood of Taiwanese patients with colorectal cancer

Jaw-Yuan Wang, Ching-Sheng Yeh, Yi-Fang Chen, Chan-Hang Wu, Jan-Sing Hsieh, Tsung-Jan Huang, Sung-Yu Huang, Shiu-Ru Lin
Pages: 737-747
Published online on: 01 May 2006

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Article

Human RAB24, interestingly and predominantly distributed in the nuclei of COS-7 cells, is colocalized with cyclophilin A and GABARAP

Maoqing Wu, Gang Yin, Xin Zhao, Chaoneng Ji, Shaohua Gu, Rong Tang, Hai Dong, Yi Xie, Yumin Mao
Pages: 749-754
Published online on: 01 May 2006

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Article

Mutation in exon 7 of PTCH deregulates SHH/PTCH/SMO signaling: Possible linkage to WNT

Vesna Musani, Philippe Gorry, Aleksandra Basta-Juzbasic, Tonci Stipic, Pavle Miklic, Sonja Levanat
Pages: 755-759
Published online on: 01 May 2006

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Article

Yes-associated protein (YAP65) in relation to Smad7 expression in human pancreatic ductal adenocarcinoma

Junchao Guo, Jörg Kleeff, Yupei Zhao, Junsheng Li, Thomas Giese, Irene Esposito, Markus W. Büchler, Murray Korc, Helmut Friess
Pages: 761-767
Published online on: 01 May 2006

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Article

Genomic abnormalities in chronic lymphocytic leukemia influence gene expression by a gene dosage effect

John D. Dickinson, Avadhut Joshi, Javeed Iqbal, Warren Sanger, Philip J. Bierman, Shantaram S. Joshi
Pages: 769-778
Published online on: 01 May 2006

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Article

The calcium-sensing receptor and vitamin D receptor expression in tertiary hyperparathyroidism

Tomasz Grzela, Witold Chudzinski, Zofia Lasiecka, Justyna Niderla, Grzegorz Wilczynski, Barbara Gornicka, Aleksander Wasiutynski, Magdalena Durlik, Anna Boszczyk, Robert Brawura-Biskupski-Samaha, Piotr Dziunycz, Lukasz Milewski, Marta Lazarczyk, Maciej Lazarczyk, Ireneusz Nawrot
Pages: 779-783
Published online on: 01 May 2006

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Article

Quantitative evaluation of partial deletions of the DAZ gene cluster

G. Letizia D'Amico, Daniela Di Benedetto, Franca M. Pezzino, Vincenza Giuffrida, Massimo Libra, Marco Fichera, Grazia Mauceri, Giancarlo Rappazzo, Rosario D'Agata, Enzo Vicari, Salvatore Travali, Aldo E. Calogero
Pages: 785-789
Published online on: 01 May 2006

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Article

Polymorphism in ABCA1 influences CSF 24S-hydroxycholesterol levels but is not a major risk factor of Alzheimer's disease

Heike Kölsch, Dieter Lütjohann, Frank Jessen, Klaus Von Bergmann, Sandra Schmitz, Horst Urbach, Wolfgang Maier, Reinhard Heun
Pages: 791-794
Published online on: 01 May 2006

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Article

CER1 is a common target of WNT and NODAL signaling pathways in human embryonic stem cells

Masuko Katoh, Masaru Katoh
Pages: 795-799
Published online on: 01 May 2006

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Article

Gene transduction of tristetraprolin or its active domain reduces TNF-α production by Jurkat T cells

Eiji Suzuki, Akito Tsutsumi, Daisuke Goto, Isao Matsumoto, Satoshi Ito, Makoto Otsu, Masafumi Onodera, Satoru Takahashi, Yukio Sato, Takayuki Sumida
Pages: 801-809
Published online on: 01 May 2006

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Article

Anandamide-induced apoptosis in Chang liver cells involves ceramide and JNK/AP-1 pathway

Michela Giuliano, Giuseppe Calvaruso, Ornella Pellerito, Patrizia Portanova, Daniela Carlisi, Renza Vento, Giovanni Tesoriere
Pages: 811-819
Published online on: 01 May 2006

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Article

Apolipoprotein-E modulates the cytotoxic effect of β-amyloid on rat brain endothelium in an isoform-dependent specific manner

Marcella Folin, Silvia Baiguera, Diego Guidolin, Rosa Di Liddo, Claudio Grandi, Eugenio De Carlo, Gastone G. Nussdorfer, Pier Paolo Parnigotto
Pages: 821-826
Published online on: 01 May 2006

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Article

Antibody to hepatitis B core antigen is associated with the development of hepatocellular carcinoma in hepatitis C virus-infected persons: A 12-year prospective study

Kazuo Tanaka, Yumiko Nagao, Tatsuya Ide, Ryukichi Kumashiro, Michio Sata
Pages: 827-832
Published online on: 01 May 2006

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Article

Synthetic peptide F2A4-K-NS mimics fibroblast growth factor-2 in vitro and is angiogenic in vivo

X. Lin, K. Takahashi, S. L. Campion, Y. Liu, G. G. Gustavsen, L. A. Peña, P. O. Zamora
Pages: 833-839
Published online on: 01 May 2006

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Article

Caspase-1 as a radio- and chemo-sensitiser in vitro and in vivo

Pilar Martín-Duque, Miguel Quintanilla, Iain McNeish, Rita Lopes, Jesús Romero, Diana Romero, Nick R. Lemoine, Santiago Ramón y Cajal, Georges Vassaux
Pages: 841-847
Published online on: 01 May 2006

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Article

Identification of a unique set of genes altered during cell-cell contact in an in vitro model of prostate cancer bone metastasis

Jun Wang, Anait S. Levenson, Robert L. Satcher
Pages: 849-856
Published online on: 01 May 2006

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Article

Relationship between the proliferative capability of hepatocytes and the intrahepatic expression of hepatocyte growth factor and c-Met in the course of cirrhosis development in rats

Hideyuki Inoue, Fumi Yokoyama, Yuko Kita, Hitoshi Yoshiji, Tatsuhiro Tsujimoto, Akihiro Deguchi, Seiji Nakai, Asahiro Morishita, Naohito Uchida, Tsutomu Masaki, Seishiro Watanabe, Shigeki Kuriyama
Pages: 857-864
Published online on: 01 May 2006

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Article

Accumulation of steroidogenic acute regulatory protein mRNA, and decrease in the secretory and proliferative activity of rat adrenocortical cells in the presence of proteasome inhibitors

Agnieska Ziolkowska, Cinzia Tortorella, Gastone G. Nussdorfer, Marcin Rucinski, Mariola Majchrzak, Ludwik K. Malendowicz
Pages: 865-868
Published online on: 01 May 2006

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Article

Deletion of the kinase domain from death-associated protein kinase enhances spatial memory in mice

Kazunori Yukawa, Tetsuji Tanaka, Tao Bai, Li Li, Yuji Tsubota, Kyoko Owada-Makabe, Masanobu Maeda, Katsuaki Hoshino, Shizuo Akira, Hiroyuki Iso
Pages: 869-873
Published online on: 01 May 2006

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Article

Increased expression of membrane TNF-α on activated peripheral CD8+ T cells in systemic lupus erythematosus

Takahiko Horiuchi, Chika Morita, Hiroshi Tsukamoto, Hiroki Mitoma, Takuya Sawabe, Shin-Ichi Harashima, Yoichiro Kashiwagi, Seiichi Okamura
Pages: 875-879
Published online on: 01 May 2006

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Article

Serum cytokine concentrations and acute graft-versus-host disease after allogeneic peripheral blood stem cell transplantation: Concurrent measurement of ten cytokines and their respective ratios using cytometric bead array

Nobuharu Fujii, Akio Hiraki, Keisuke Aoe, Tomoyuki Murakami, Kazuma Ikeda, Kozo Masuda, Keitaro Matsuo, Katsuji Shinagawa, Fumihiko Ishimaru, Kazuro Sugi, Zbigniew Darzynkiewicz, Mitsune Tanimoto
Pages: 881-885
Published online on: 01 May 2006

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Article

Tumour necrosis factor-α: prognostic role and relationship with interleukin-8 and endothelin-1 in non-small cell lung cancer

Laura Boldrini, Silvia Gisfredi, Silvia Ursino, Marco Lucchi, Franca Melfi, Alfredo Mussi, Fulvio Basolo, Gabriella Fontanini
Pages: 887-892
Published online on: 01 May 2006

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Article

STI571 (Glivec) induces cell death in the gastrointestinal stromal tumor cell line, GIST-T1, via endoplasmic reticulum stress response

Hajime Nakatani, Keijiro Araki, Toufeng Jin, Michiya Kobayashi, Takeki Sugimoto, Toyokazu Akimori, Tsutomu Namikawa, Ken Okamoto, Takumi Nakano, Takehiro Okabayashi, Norihiro Hokimoto, Hiroyuki Kitagawa, Takahiro Taguchi
Pages: 893-897
Published online on: 01 May 2006

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Article

Amelioration of liver fibrogenesis by dual inhibition of PDGF and TGF-β with a combination of imatinib mesylate and ACE inhibitor in rats

Hitoshi Yoshiji, Shigeki Kuriyama, Ryuichi Noguchi, Yasuhide Ikenaka, Junichi Yoshii, Koji Yanase, Tadashi Namisaki, Mitsuteru Kitade, Masaharu Yamazaki, Kiyoshi Asada, Takemi Akahane, Tatsuhiro Tsujimoto, Masahito Uemura, Hiroshi Fukui
Pages: 899-904
Published online on: 01 May 2006

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Article

In vitro and in vivo immunomodulating activities of Shoyu polysaccharides from soy sauce

Hiroaki Matsushita, Makio Kobayashi, Ryo-Ichi Tsukiyama, Kenji Yamamoto
Pages: 905-909
Published online on: 01 May 2006

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Article

CD4+ T cells and the Th1/Th2 imbalance are implicated in the pathogenesis of Graves' ophthalmopathy

Ning Xia, Suxian Zhou, Yuzhen Liang, Changqing Xiao, Hanlei Shen, Hailin Pan, Hongming Deng, Naizun Wang, Qingdi Q. Li
Pages: 911-916
Published online on: 01 May 2006

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Article

Abnormal DNA end-joining activity in human head and neck cancer

Ki-Hyuk Shin, Mo K. Kang, Reuben H. Kim, Ayako Kameta, Marcel A. Baluda, No-Hee Park
Pages: 917-924
Published online on: 01 May 2006

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Article

Adrenomedullin binding protein-1 is downregulated during polymicrobial sepsis in the rat

Yingjie Cui, Youxin Ji, Rongqian Wu, Mian Zhou, Ping Wang
Pages: 925-929
Published online on: 01 May 2006

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Article

Apoptotic-inducing activity of novel polycyclic aromatic compounds in human leukemic cells

Kristin R. Landis-Piwowar, Di Chen, Qiuzhi Cindy Cui, Vesna Minic, Frederick F. Becker, Bimal K. Banik, Q. Ping Dou
Pages: 931-935
Published online on: 01 May 2006

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Article

Expression of pigment epithelial derived factor is reduced in non-small cell lung cancer and is linked to clinical outcome

Lijian Zhang, Jinfeng Chen, Yang Ke, Robert E. Mansel, Wen G. Jiang
Pages: 937-944
Published online on: 01 May 2006

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Article

Apoptotic activity of a novel synthetic cantharidin analogue on hepatoma cell lines

Stanton Hon Lung Kok, Chung Hin Chui, Wing Sze Lam, Jien Chen, Fung Yi Lau, Gregory Yin Ming Cheng, Raymond Siu Ming Wong, Paul Po San Lai, Thomas Wai Tong Leung, Johnny Cheuk On Tang, Albert Sun Chi Chan
Pages: 945-949
Published online on: 01 May 2006

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Article

Comparative integromics on BMP/GDF family

Yuriko Katoh, Masaru Katoh
Pages: 951-955
Published online on: 01 May 2006

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Article

Ethanol extract from Artemisia vestita, a traditional Tibetan medicine, exerts anti-sepsis action through down-regulating the MAPK and NF-κB pathways

Yang Sun, Yi-Hua Li, Xing-Xin Wu, Wei Zheng, Zong-Hui Guo, Yang Li, Ting Chen, Zi-Chun Hua, Qiang Xu
Pages: 957-962
Published online on: 01 May 2006

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Review Open Access

Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Review Open Access

Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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