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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May 2006 Volume 17 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Chemokines in vascular pathology (Review)

Stavros Apostolakis, Emmanouil G. Papadakis, ELias Krambovitis, Demetrios A. Spandidos
Pages: 691-701
Published online on: 01 May 2006

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Article

Protein phosphatase 2A interacts with Chk2 and regulates phosphorylation at Thr-68 after cisplatin treatment of human ovarian cancer cells

Xiaobing Liang, Eddie Reed, Jing Jie Yu
Pages: 703-708
Published online on: 01 May 2006

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Article

Identification and localization of adrenomedullin-storing cardiac mast cells

Anna S. Belloni, Lucia Petrelli, Diego Guidolin, Renzo De Toni, Sergio Bova, Raffaella Spinazzi, Gino Gerosa, Gian Paolo Rossi, Gastone G. Nussdorfer
Pages: 709-713
Published online on: 01 May 2006

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Article

E2F-1 is a critical modulator of cellular senescence in human cancer

Chaehwa Park, Inkyoung Lee, Won Ki Kang
Pages: 715-720
Published online on: 01 May 2006

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Article

Efficient differentiation into skin cells of bone marrow cells recovered in a pellet after density gradient fractionation

Reinhold J. Medina, Ken Kataoka, Masahiro Miyazaki, Nam-Ho Huh
Pages: 721-727
Published online on: 01 May 2006

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Article

Non-muscle myosin heavy chain IIA and IIB interact and co-localize in living cells: Relevance for MYH9-related disease

Monica Marini, Maurizio Bruschi, Alessandro Pecci, Roberta Romagnoli, Luca Musante, Giovanni Candiano, Gian Marco Ghiggeri, Carlo Balduini, Marco Seri, Roberto Ravazzolo
Pages: 729-736
Published online on: 01 May 2006

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Article

Development and evaluation of a colorimetric membrane-array method for the detection of circulating tumor cells in the peripheral blood of Taiwanese patients with colorectal cancer

Jaw-Yuan Wang, Ching-Sheng Yeh, Yi-Fang Chen, Chan-Hang Wu, Jan-Sing Hsieh, Tsung-Jan Huang, Sung-Yu Huang, Shiu-Ru Lin
Pages: 737-747
Published online on: 01 May 2006

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Article

Human RAB24, interestingly and predominantly distributed in the nuclei of COS-7 cells, is colocalized with cyclophilin A and GABARAP

Maoqing Wu, Gang Yin, Xin Zhao, Chaoneng Ji, Shaohua Gu, Rong Tang, Hai Dong, Yi Xie, Yumin Mao
Pages: 749-754
Published online on: 01 May 2006

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Article

Mutation in exon 7 of PTCH deregulates SHH/PTCH/SMO signaling: Possible linkage to WNT

Vesna Musani, Philippe Gorry, Aleksandra Basta-Juzbasic, Tonci Stipic, Pavle Miklic, Sonja Levanat
Pages: 755-759
Published online on: 01 May 2006

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Article

Yes-associated protein (YAP65) in relation to Smad7 expression in human pancreatic ductal adenocarcinoma

Junchao Guo, Jörg Kleeff, Yupei Zhao, Junsheng Li, Thomas Giese, Irene Esposito, Markus W. Büchler, Murray Korc, Helmut Friess
Pages: 761-767
Published online on: 01 May 2006

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Article

Genomic abnormalities in chronic lymphocytic leukemia influence gene expression by a gene dosage effect

John D. Dickinson, Avadhut Joshi, Javeed Iqbal, Warren Sanger, Philip J. Bierman, Shantaram S. Joshi
Pages: 769-778
Published online on: 01 May 2006

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Article

The calcium-sensing receptor and vitamin D receptor expression in tertiary hyperparathyroidism

Tomasz Grzela, Witold Chudzinski, Zofia Lasiecka, Justyna Niderla, Grzegorz Wilczynski, Barbara Gornicka, Aleksander Wasiutynski, Magdalena Durlik, Anna Boszczyk, Robert Brawura-Biskupski-Samaha, Piotr Dziunycz, Lukasz Milewski, Marta Lazarczyk, Maciej Lazarczyk, Ireneusz Nawrot
Pages: 779-783
Published online on: 01 May 2006

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Article

Quantitative evaluation of partial deletions of the DAZ gene cluster

G. Letizia D'Amico, Daniela Di Benedetto, Franca M. Pezzino, Vincenza Giuffrida, Massimo Libra, Marco Fichera, Grazia Mauceri, Giancarlo Rappazzo, Rosario D'Agata, Enzo Vicari, Salvatore Travali, Aldo E. Calogero
Pages: 785-789
Published online on: 01 May 2006

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Article

Polymorphism in ABCA1 influences CSF 24S-hydroxycholesterol levels but is not a major risk factor of Alzheimer's disease

Heike Kölsch, Dieter Lütjohann, Frank Jessen, Klaus Von Bergmann, Sandra Schmitz, Horst Urbach, Wolfgang Maier, Reinhard Heun
Pages: 791-794
Published online on: 01 May 2006

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Article

CER1 is a common target of WNT and NODAL signaling pathways in human embryonic stem cells

Masuko Katoh, Masaru Katoh
Pages: 795-799
Published online on: 01 May 2006

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Article

Gene transduction of tristetraprolin or its active domain reduces TNF-α production by Jurkat T cells

Eiji Suzuki, Akito Tsutsumi, Daisuke Goto, Isao Matsumoto, Satoshi Ito, Makoto Otsu, Masafumi Onodera, Satoru Takahashi, Yukio Sato, Takayuki Sumida
Pages: 801-809
Published online on: 01 May 2006

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Article

Anandamide-induced apoptosis in Chang liver cells involves ceramide and JNK/AP-1 pathway

Michela Giuliano, Giuseppe Calvaruso, Ornella Pellerito, Patrizia Portanova, Daniela Carlisi, Renza Vento, Giovanni Tesoriere
Pages: 811-819
Published online on: 01 May 2006

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Article

Apolipoprotein-E modulates the cytotoxic effect of β-amyloid on rat brain endothelium in an isoform-dependent specific manner

Marcella Folin, Silvia Baiguera, Diego Guidolin, Rosa Di Liddo, Claudio Grandi, Eugenio De Carlo, Gastone G. Nussdorfer, Pier Paolo Parnigotto
Pages: 821-826
Published online on: 01 May 2006

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Article

Antibody to hepatitis B core antigen is associated with the development of hepatocellular carcinoma in hepatitis C virus-infected persons: A 12-year prospective study

Kazuo Tanaka, Yumiko Nagao, Tatsuya Ide, Ryukichi Kumashiro, Michio Sata
Pages: 827-832
Published online on: 01 May 2006

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Article

Synthetic peptide F2A4-K-NS mimics fibroblast growth factor-2 in vitro and is angiogenic in vivo

X. Lin, K. Takahashi, S. L. Campion, Y. Liu, G. G. Gustavsen, L. A. Peña, P. O. Zamora
Pages: 833-839
Published online on: 01 May 2006

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Article

Caspase-1 as a radio- and chemo-sensitiser in vitro and in vivo

Pilar Martín-Duque, Miguel Quintanilla, Iain McNeish, Rita Lopes, Jesús Romero, Diana Romero, Nick R. Lemoine, Santiago Ramón y Cajal, Georges Vassaux
Pages: 841-847
Published online on: 01 May 2006

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Article

Identification of a unique set of genes altered during cell-cell contact in an in vitro model of prostate cancer bone metastasis

Jun Wang, Anait S. Levenson, Robert L. Satcher
Pages: 849-856
Published online on: 01 May 2006

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Article

Relationship between the proliferative capability of hepatocytes and the intrahepatic expression of hepatocyte growth factor and c-Met in the course of cirrhosis development in rats

Hideyuki Inoue, Fumi Yokoyama, Yuko Kita, Hitoshi Yoshiji, Tatsuhiro Tsujimoto, Akihiro Deguchi, Seiji Nakai, Asahiro Morishita, Naohito Uchida, Tsutomu Masaki, Seishiro Watanabe, Shigeki Kuriyama
Pages: 857-864
Published online on: 01 May 2006

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Article

Accumulation of steroidogenic acute regulatory protein mRNA, and decrease in the secretory and proliferative activity of rat adrenocortical cells in the presence of proteasome inhibitors

Agnieska Ziolkowska, Cinzia Tortorella, Gastone G. Nussdorfer, Marcin Rucinski, Mariola Majchrzak, Ludwik K. Malendowicz
Pages: 865-868
Published online on: 01 May 2006

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Article

Deletion of the kinase domain from death-associated protein kinase enhances spatial memory in mice

Kazunori Yukawa, Tetsuji Tanaka, Tao Bai, Li Li, Yuji Tsubota, Kyoko Owada-Makabe, Masanobu Maeda, Katsuaki Hoshino, Shizuo Akira, Hiroyuki Iso
Pages: 869-873
Published online on: 01 May 2006

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Article

Increased expression of membrane TNF-α on activated peripheral CD8+ T cells in systemic lupus erythematosus

Takahiko Horiuchi, Chika Morita, Hiroshi Tsukamoto, Hiroki Mitoma, Takuya Sawabe, Shin-Ichi Harashima, Yoichiro Kashiwagi, Seiichi Okamura
Pages: 875-879
Published online on: 01 May 2006

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Article

Serum cytokine concentrations and acute graft-versus-host disease after allogeneic peripheral blood stem cell transplantation: Concurrent measurement of ten cytokines and their respective ratios using cytometric bead array

Nobuharu Fujii, Akio Hiraki, Keisuke Aoe, Tomoyuki Murakami, Kazuma Ikeda, Kozo Masuda, Keitaro Matsuo, Katsuji Shinagawa, Fumihiko Ishimaru, Kazuro Sugi, Zbigniew Darzynkiewicz, Mitsune Tanimoto
Pages: 881-885
Published online on: 01 May 2006

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Article

Tumour necrosis factor-α: prognostic role and relationship with interleukin-8 and endothelin-1 in non-small cell lung cancer

Laura Boldrini, Silvia Gisfredi, Silvia Ursino, Marco Lucchi, Franca Melfi, Alfredo Mussi, Fulvio Basolo, Gabriella Fontanini
Pages: 887-892
Published online on: 01 May 2006

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Article

STI571 (Glivec) induces cell death in the gastrointestinal stromal tumor cell line, GIST-T1, via endoplasmic reticulum stress response

Hajime Nakatani, Keijiro Araki, Toufeng Jin, Michiya Kobayashi, Takeki Sugimoto, Toyokazu Akimori, Tsutomu Namikawa, Ken Okamoto, Takumi Nakano, Takehiro Okabayashi, Norihiro Hokimoto, Hiroyuki Kitagawa, Takahiro Taguchi
Pages: 893-897
Published online on: 01 May 2006

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Article

Amelioration of liver fibrogenesis by dual inhibition of PDGF and TGF-β with a combination of imatinib mesylate and ACE inhibitor in rats

Hitoshi Yoshiji, Shigeki Kuriyama, Ryuichi Noguchi, Yasuhide Ikenaka, Junichi Yoshii, Koji Yanase, Tadashi Namisaki, Mitsuteru Kitade, Masaharu Yamazaki, Kiyoshi Asada, Takemi Akahane, Tatsuhiro Tsujimoto, Masahito Uemura, Hiroshi Fukui
Pages: 899-904
Published online on: 01 May 2006

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Article

In vitro and in vivo immunomodulating activities of Shoyu polysaccharides from soy sauce

Hiroaki Matsushita, Makio Kobayashi, Ryo-Ichi Tsukiyama, Kenji Yamamoto
Pages: 905-909
Published online on: 01 May 2006

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Article

CD4+ T cells and the Th1/Th2 imbalance are implicated in the pathogenesis of Graves' ophthalmopathy

Ning Xia, Suxian Zhou, Yuzhen Liang, Changqing Xiao, Hanlei Shen, Hailin Pan, Hongming Deng, Naizun Wang, Qingdi Q. Li
Pages: 911-916
Published online on: 01 May 2006

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Article

Abnormal DNA end-joining activity in human head and neck cancer

Ki-Hyuk Shin, Mo K. Kang, Reuben H. Kim, Ayako Kameta, Marcel A. Baluda, No-Hee Park
Pages: 917-924
Published online on: 01 May 2006

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Article

Adrenomedullin binding protein-1 is downregulated during polymicrobial sepsis in the rat

Yingjie Cui, Youxin Ji, Rongqian Wu, Mian Zhou, Ping Wang
Pages: 925-929
Published online on: 01 May 2006

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Article

Apoptotic-inducing activity of novel polycyclic aromatic compounds in human leukemic cells

Kristin R. Landis-Piwowar, Di Chen, Qiuzhi Cindy Cui, Vesna Minic, Frederick F. Becker, Bimal K. Banik, Q. Ping Dou
Pages: 931-935
Published online on: 01 May 2006

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Article

Expression of pigment epithelial derived factor is reduced in non-small cell lung cancer and is linked to clinical outcome

Lijian Zhang, Jinfeng Chen, Yang Ke, Robert E. Mansel, Wen G. Jiang
Pages: 937-944
Published online on: 01 May 2006

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Article

Apoptotic activity of a novel synthetic cantharidin analogue on hepatoma cell lines

Stanton Hon Lung Kok, Chung Hin Chui, Wing Sze Lam, Jien Chen, Fung Yi Lau, Gregory Yin Ming Cheng, Raymond Siu Ming Wong, Paul Po San Lai, Thomas Wai Tong Leung, Johnny Cheuk On Tang, Albert Sun Chi Chan
Pages: 945-949
Published online on: 01 May 2006

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Article

Comparative integromics on BMP/GDF family

Yuriko Katoh, Masaru Katoh
Pages: 951-955
Published online on: 01 May 2006

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Article

Ethanol extract from Artemisia vestita, a traditional Tibetan medicine, exerts anti-sepsis action through down-regulating the MAPK and NF-κB pathways

Yang Sun, Yi-Hua Li, Xing-Xin Wu, Wei Zheng, Zong-Hui Guo, Yang Li, Ting Chen, Zi-Chun Hua, Qiang Xu
Pages: 957-962
Published online on: 01 May 2006

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Macrophage SH3 domain‑containing GRB2‑like protein B1 is required for Rab7‑mediated mitophagy in inflammation during sea water drowning acute lung injury

Hongjuan Ning, Jingyu Deng, Yongheng Gao, Wei Zhang, Jian Chen, Xian Guo, Faguang Jin
Article Number: 138
Published online on: 24 March 2026

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Article Open Access

Deferoxamine mitigates neuronal loss following spinal cord injury via ferroptosis inhibition and Nrf2/HO‑1 pathway activation

Ziqian Ma, Xinwei Zhang, Tao Liu, Yan Zhang, Guanghao Li, Xin Yuan, Benqiang Tang, Hangyi Zhao, Liang Liu, Xueming Chen
Article Number: 137
Published online on: 23 March 2026

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Review Open Access

USP10 deubiquitinase: Physiological function, diseases and therapeutic target (Review)

Linlin Zhang, Huajing Sun, Zifan Wang, Zhimei Wang, Qiang Mu, Yukun Liu
Article Number: 136
Published online on: 23 March 2026

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Article Open Access

Siglec‑15 dysregulation and its therapeutic implications in new‑onset type 1 diabetes 

Heming Guo, Yunwen Tao, Sicheng Li, Ying Gu, Yiting Huang, Chen Fang, Ji Hu
Article Number: 135
Published online on: 20 March 2026

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Article Open Access

ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing

Yan Zhao, Yuankai Zhang, Tian Lei, Shangqing Zhang, Kai Nan, Xin Zhang, Li-Hong Fan
Article Number: 134
Published online on: 19 March 2026

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Review Open Access

Targeting pyroptosis in renal fibrosis: From molecular mechanisms to therapeutic horizons (Review)

Yihuai Tian, Quwu Mushuo, Hui Fan, Hongwei Su, Jianchun Li, Qiong Zhang
Article Number: 133
Published online on: 19 March 2026

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Expression of Concern Open Access

[Expression of Concern] Fasudil, a Rho‑associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats

Haishan Song, Dianwen Gao
Article Number: 132
Published online on: 18 March 2026

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Review Open Access

Epigenetic regulation in a high-sugar environment (Review)

Huili Zhou, Xinhe Lv, Yu Liang, Dehai Yu, Wanning Wang
Article Number: 131
Published online on: 17 March 2026

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Review Open Access

The roles and heterogeneity of CD8+ T cells in inflammatory bowel disease: A narrative review of insights from single‑cell transcriptomics (Review)

Rui Zhong, Jing Guo, Wujie Ye, Zhihui Deng, Huangan Wu, Qin Qi, Guona Li, Lu Zhu, Yan Huang, Luyi Wu
Article Number: 130
Published online on: 17 March 2026

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Review Open Access

Mechanism of action and clinical application of autophagy in multiple sclerosis (Review)

Dongmei Wang, Qizhi Fu, Ying Zhao, Guangda Li, Yongjie Bai, Yang Yang, Hongna Song, Mingwei Wang, Hua Fan
Article Number: 129
Published online on: 17 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation

Mamiko Hie, Natsumi Iitsuka, Tomoyo Otsuka, Ikuyo Tsukamoto
Article Number: 128
Published online on: 16 March 2026

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Review Open Access

Mechanotransduction and its impact on regenerative medicine in orthopedic rehabilitation (Review)

Baohui Wang, Xueqin Zeng, Huajian Liu, Liang Li, Tao Lei, Yafeng Li, Qing Fang, Yi Cao, Bo Dong
Article Number: 127
Published online on: 13 March 2026

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Article Open Access

4‑Acetylantrocamol LT3 suppresses colorectal cancer growth and metastasis via PI3K/AKT and MAPK pathway modulation

Kuen-Tze Lin, Yu-Chieh Hsieh, Pi-Kai Chang, Chih-Wei Lai, Shih-Yu Lee, I-Chuan Yen
Article Number: 126
Published online on: 13 March 2026

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Roles of ubiquitin‑specific peptidase 22 in cellular fate: From embryonic survival to tissue repair, inflammation and metabolism (Review)

Jia-Nan Xiang, Chen-Yang Zhou, Yu-Di Zhao, Xiao Xu, Sun-Bin Ling
Article Number: 125
Published online on: 12 March 2026

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m6A in adipose tissue inflammation: A novel regulator of obesity and metabolic diseases (Review)

Xiaoting Yang, Xiaodan Wang, Haojun Tang, Shuangxi Tu, Kai Yin, Xiao Zhu
Article Number: 124
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Visfatin/PBEF/Nampt induces EMMPRIN and MMP‑9 production in macrophages via the NAMPT‑MAPK (p38, ERK1/2)‑NF‑κB signaling pathway

Yuqi Fan, Shu Meng, Yue Wang, Jiatian Cao, Changqian Wang
Article Number: 123
Published online on: 12 March 2026

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Article Open Access

IL‑37/IL‑1R8 blocks keratinocyte acantholysis via suppressing ADAM17/EGFR

Fengxia Hu, Wenjing Chen, Qian Wang, Xiaoyu Zhang, Fuyang Xiao, Jinying Zhang, Junqin Liang
Article Number: 122
Published online on: 12 March 2026

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Reactive oxygen species in fetal growth restriction mechanisms and therapeutic directions (Review)

Di Cheng, Songbin Yang, Cuilan Wang, Kefeng Fan, Fengchun Gao, Qian Sun
Article Number: 121
Published online on: 12 March 2026

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Research progress on the molecular mechanisms of tanshinone IIA in the treatment of cardiovascular and cerebrovascular diseases (Review)

Wen Pei, Ping Lu, Chenhuan Ding, Ying Li, Yong Li
Article Number: 120
Published online on: 12 March 2026

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Ferritin in ferroptosis: Implications for neurodegenerative diseases (Review)

Wenjing Chen, Heng Tian, Ran Wei, Xiaomei Chen, Yiwen Jia
Article Number: 119
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling  

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang
Article Number: 118
Published online on: 09 March 2026

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Article Open Access

HELLS inhibits autophagy‑dependent ferroptosis in nasopharyngeal carcinoma by modulating the Nrf2/HO‑1/GPX4 pathway

Chengxun Jin, Jinqiu Li, Siqi Han, Chaoluomeng Bai, Jingpu Yang, Zonggui Wang
Article Number: 117
Published online on: 09 March 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis

Ying Zhang, Hong Cao, Yue-Yue Hu, Hua Wang, Chang-Jun Zhang
Article Number: 116
Published online on: 09 March 2026

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Article Open Access

Propofol upregulates MFG‑E8 in BV2 cells to inhibit pyroptosis mediated by the NF‑κB/NLRP3 pathway, thereby ameliorating ischemic‑reperfusion neuronal injury

Shewei Guo, Yingwei Zhen, Guosheng Zhou, Zhihua Zhao
Article Number: 115
Published online on: 05 March 2026

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Article Open Access

Exosomal circ0000549 promotes MNNG‑induced gastric cancer through miR‑15b‑5p/KIF1B

Zhaofeng Liang, Zihan Gao, Yue Zhang, Jiajia Song, Hui Qian, Xuezhong Xu
Article Number: 114
Published online on: 04 March 2026

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Expression of Concern Open Access

[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy  

Fangfang Li, Ning Zhang, Qingqing Wu, Yuan Yuan, Zheng Yang, Mengqiao Zhou, Jinxiu Zhu, Qizhu Tang
Article Number: 113
Published online on: 04 March 2026

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Review Open Access

Treatment of pulmonary fibrosis: From disease mechanisms to future novel therapies (Review)

Sen Lu, Yunfei Liu, Xiaohua Li, Qipeng Yao
Article Number: 112
Published online on: 03 March 2026

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Review Open Access

Research progress in single‑cell omics technologies for kidney disease (Review)

Jia Xu, Ziwei Chen, Shengyao Li, Xiaoya Wang, Ming Chen
Article Number: 111
Published online on: 03 March 2026

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Review Open Access

CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review)

Xiuping Lai, Yan Yan, Lu Sun, Zili Lei, Yanhong Yang
Article Number: 110
Published online on: 03 March 2026

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Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)

Sen Lu, Jiale Tong, Jing Jiang, Qin Zhang, Youjin Huang
Article Number: 109
Published online on: 03 March 2026

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The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)

Yingying Zhang, Ruxin Shen
Article Number: 108
Published online on: 02 March 2026

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Review Open Access

Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

Bojiao Yang, Feng Li, Guimao Cao, Mingtu Nuo, Yaxin Shi, Zilu Wang, Jing Jia, Wei Shi, Zhiyong Liu
Article Number: 107
Published online on: 02 March 2026

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Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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June-2026 Volume 57 Issue 6

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Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Astragaloside IV targets TUBB4B to inhibit proliferation and promote apoptosis of pituitary tumor cells via the STMN1/ERK pathway

Jiale Li, Yufei Qu, Wenge Zhang, Zexu Yang, Yangdong Zeng, Jisheng Xu, Kuncen Xie, Qi Liu
Article Number: 151
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation

Keng Wu, Wenming Xu, Qiong You, Runmin Guo, Jianqiang Feng, Changran Zhang, Wen Wu
Article Number: 150
Published online on: 01 April 2026

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Review Open Access

Animal models accurately representing acute liver failure (Review)

Sang Luo, Fang Wu, Yiran Jin, Xiaofen Huang, Dan Liu, Bingren Tian
Article Number: 149
Published online on: 01 April 2026

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Correction Open Access

[Corrigendum] Influence of aspirin on the CX3CL1/CX3CR1 signaling pathway in acute pulmonary embolism 

Zhirong Zhang, Weiji Yang, Rongbiao Ying, Ying Shi, Huifang Jiang, Danli Cai, Jing Kuang, Ruhui Yang, Lingcong Wang
Article Number: 148
Published online on: 31 March 2026

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Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review)

Jing Mao, Mandi Luo, Lei Ruan, Cuntai Zhang
Article Number: 147
Published online on: 31 March 2026

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Role of aging‑related cytokines in neurodegenerative disease (Review)

Xinke Dai, Xinran Rao, Yuandi Wang, Weijiang Zhao
Article Number: 146
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] DTX3L is upregulated in glioma and is associated with glioma progression

Peng Xu, Xuelei Tao, Chengjin Zhao, Qingfeng Huang, Hao Chang, Na Ban, Yuanqi Bei, Xiaojie Xia, Chaoyan Shen, Kun Wang, Li Xu, Peizhang Wu, Jianbing Ren, Donglin Wang
Article Number: 145
Published online on: 30 March 2026

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Role of itaconate in intestinal disease (Review)

Xin Li, Qian Liu, Jiajia Li, Li Zhang, Shun Yao, Lulu Tang, Bingqi Yang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 144
Published online on: 27 March 2026

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Unveiling lactylation: A novel frontier in the pathogenesis of diabetic nephropathy (Review)

Yuanyuan Xiao, Niansong Wang, Dingkun Gui, Youhua Xu
Article Number: 143
Published online on: 27 March 2026

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Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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