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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2007 Volume 20 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Decreased expression of claudin-1 correlates with recurrence status in breast cancer

Satoko Morohashi, Tomomi Kusumi, Fuyuki Sato, Hiroki Odagiri, Hiroki Chiba, Shuichi Yoshihara, Kenichi Hakamada, Mutsuo Sasaki, Hiroshi Kijima
Pages: 139-143
Published online on: 01 August 2007

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Article

Proteomic profiling reveals a severely perturbed protein expression pattern in aged skeletal muscle

Kathleen O'Connell, Joan Gannon, Philip Doran, Kay Ohlendieck
Pages: 145-153
Published online on: 01 August 2007

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Article

Identifying prostate carcinoma by MALDI-Imaging

Kristina Schwamborn, René C. Krieg, Marcus Reska, Gerhard Jakse, Ruth Knuechel, Axel Wellmann
Pages: 155-159
Published online on: 01 August 2007

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Article

Differential expression of vasoactive intestinal peptide receptor 1 expression in inflammatory bowel disease

Tomomi Yukawa, Nobuhide Oshitani, Hirokazu Yamagami, Kenji Watanabe, Kazuhide Higuchi, Tetsuo Arakawa
Pages: 161-167
Published online on: 01 August 2007

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Article

Late-onset olfactory deficits and mitral cell loss in mice lacking prion protein with ectopic expression of Doppel

Chi-Kyeong Kim, Akikazu Sakudo, Yojiro Taniuchi, Kazuto Shigematsu, Chung-Boo Kang, Keiichi Saeki, Yoshitsugu Matsumoto, Suehiro Sakaguchi, Shigeyoshi Itohara, Takashi Onodera
Pages: 169-176
Published online on: 01 August 2007

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Article

Detection of proteolytic cleavages of diabetes-associated protein IA-2β in the pancreas and the brain using novel anti-IA-2β monoclonal antibodies

Tomiko Kawakami, Keiichi Saeki, Natsumi Takeyama, Guoying Wu, Akikazu Sakudo, Yoshitsugu Matsumoto, Toshiharu Hayashi, Takashi Onodera
Pages: 177-185
Published online on: 01 August 2007

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Article

Ethyl pyruvate induces necrosis-to-apoptosis switch and inhibits high mobility group box protein 1 release in A549 lung adenocarcinoma cells

Sung-Chul Lim, Jeong Eun Choi, Cho Hee Kim, Hong-Quan Duong, Gui-Ae Jeong, Ho Sung Kang, Song Iy Han
Pages: 187-192
Published online on: 01 August 2007

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Article

Systemic and local levels of fetuin-A in calcific aortic valve stenosis

Jens J. Kaden, Jochen O. Reinöhl, Birgit Blesch, Martina Brueckmann, Dariusch Haghi, Martin Borggrefe, Fabian Schmitz, Sebastian Klomfass, Manuela Pillich, Jan R. Ortlepp
Pages: 193-197
Published online on: 01 August 2007

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Article

Combination of high-resolution magic angle spinning proton magnetic resonance spectroscopy and microscale genomics to type brain tumor biopsies

A. Aria Tzika, Loukas Astrakas, Haihui Cao, Dionyssios Mintzopoulos, Ovidiu C. Andronesi, Michael Mindrinos, Jiangwen Zhang, Laurence G. Rahme, Konstantinos D. Blekas, Aristidis C. Likas, Nikolas P. Galatsanos, Rona S. Carroll, Peter M. Black
Pages: 199-208
Published online on: 01 August 2007

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Article

Gastrodia elata Blume protects against stress-induced gastric mucosal lesions in mice

Sang-Mi An, Chul-Hong Park, Jin-Chul Heo, Ja-Young Park, Sang-Uk Woo, Ji-Hye Seo, Mi-Soon Lee, Kang-Jin Cho, Hyun-Suk Cho, Heung Mook Shin, Sang-Han Lee
Pages: 209-215
Published online on: 01 August 2007

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Article

Fibroblasts mediate induction of high mobility group box protein 1 in lung epithelial cancer cells by diffusible factors

Babett Bartling, Christine Fuchs, Rolf-Edgar Silber, Andreas Simm
Pages: 217-224
Published online on: 01 August 2007

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Article

Gene amplifications at chromosome 7 of the human gastric cancer genome

Sanghwa Yang
Pages: 225-231
Published online on: 01 August 2007

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Article

Kinesin gene variability may affect tau phosphorylation in early Alzheimer's disease

Malin E. Andersson, Annica Sjölander, Niels Andreasen, Lennart Minthon, Oskar Hansson, Nenad Bogdanovic, Christina Jern, Katarina Jood, Anders Wallin, Kaj Blennow, Henrik Zetterberg
Pages: 233-239
Published online on: 01 August 2007

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Article

Interleukin-18 regulates T helper 1 or 2 immune responses of human cord blood CD4+ Vα24+Vβ11+ natural killer T cells

Yuka Fujibayashi, Yoshihiro Fujimori, Ikuyo Kasumoto, Shunro Kai, Hiroshi Hara, Haruki Okamura, Hiroko Tsutsui, Hiroyasu Ogawa, Kenji Nakanishi
Pages: 241-245
Published online on: 01 August 2007

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Article

Biased usage of synovial immunoglobulin heavy chain variable region 4 by the anti-glucose-6-phosphate isomerase antibody in patients with rheumatoid arthritis

Taichi Hayashi, Isao Matsumoto, Takanori Yasukochi, Mizuko Mamura, Daisuke Goto, Satoshi Ito, Akito Tsutsumi, Takayuki Sumida
Pages: 247-253
Published online on: 01 August 2007

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Article

Expression of neuromedins S and U and their receptors in the hypothalamus and endocrine glands of the rat

Marcin Rucinski, Agnieszka Ziolkowska, Giuliano Neri, Marcin Trejter, Tomasz Zemleduch, Marianna Tyczewska, Gastone G. Nussdorfer, Ludwik K. Malendowicz
Pages: 255-259
Published online on: 01 August 2007

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Article

Characterization of the effects of anti-aging medicine Fructus lycii on β-amyloid peptide neurotoxicity

Man-Shan Yu, Cora Sau-Wan Lai, Yuen-Shan Ho, Sze-Yong Zee, Kwok-Fai So, Wai-Hung Yuen, Raymond Chuen-Chung Chang
Pages: 261-268
Published online on: 01 August 2007

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Article

Comparative integromics on JMJD2A, JMJD2B and JMJD2C: Preferential expression of JMJD2C in undifferentiated ES cells

Yuriko Katoh, Masaru Katoh
Pages: 269-273
Published online on: 01 August 2007

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

miR‑205: A dual regulator of angiogenesis in health and disease (Review)

Maria Oltra, Miriam Martínez‑Santos, Maria Ybarra, Maria Pires, Chiara Ceresoni, Clara Gomis‑Coloma, Cristina Medina‑Trillo, Javier Sancho, Jorge Barcia
Article Number: 51
Published online on: 29 December 2025

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Astragaloside IV: A multipotent phytochemical for treating fibrotic diseases (Review)

Mingyu Wu, Ke Li, Jiabin Wu, Qiuyu Zhang, Xiaotong Ma, Wei Dai, Haoyang Gao, Xianyi Ding, Wenhong Wang, Weihua Xiao
Article Number: 50
Published online on: 24 December 2025

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Review Open Access

Activating transcription factors: Orchestrators of macrophage biology in pathological settings (Review)

Yue-Chen Liu, Jia-Wei Zhao, Xiong-Tao Yue, Qi-Jie Chen, Shan-Jie Rong, Shi-Wei Liu, Fei Sun, Chun-Liang Yang, Cong-Yi Wang
Article Number: 49
Published online on: 24 December 2025

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Review Open Access

Role of SIRT3 in digestive system diseases and therapeutic prospects (Review)

Jiajia Li, Qian Liu, Shun Yao, Xin Li, Li Zhang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 48
Published online on: 22 December 2025

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Article Open Access

Recombinant ADAMTS‑1 promotes muscle regeneration accompanied by downregulation of Notch signaling

Jin-Hwa Kim, Sang-Hyup Lee, Sang-Yoon Kim, Jeong-Won Kim, Ji-Soo Jeong, Eun-Hye Chung, Su-Ha Lee, Chang-Yeop Kim, Bong-Keun Choi, Je-Won Ko, Tae-Won Kim
Article Number: 47
Published online on: 22 December 2025

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Review Open Access

A comprehensive review on pain: Model, target, therapy, and prospect (Review)

Chenyu Chang, Xutao Wu, Kejia Liu, Lei Wang, Mozili Adu, Qingyuan Lin, Huilian Huang, Qinge Ma, Rongrui Wei, Xiaoyun Wang, Wenmin Liu
Article Number: 46
Published online on: 17 December 2025

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Retraction Open Access

[Retracted] Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore

Yanbing Zhao, Yuxuan Guo, Yuqiong Chen, Shuang Liu, Nan Wu, Dalin Jia
Article Number: 45
Published online on: 15 December 2025

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Review Open Access

Nanomaterials and exercise interventions: A synergistic approach for atherosclerosis therapy (Review)

Quanquan Zhou, Ge‑Lin Zhang, Weitong Sun, Jiayi Cai, Li-Hua Yu
Article Number: 44
Published online on: 10 December 2025

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Article Open Access

Selective autophagic degradation of glycolytic activator PFKFB3 contributes to maintaining intestinal epithelial barrier in inflammatory bowel disease

Yiyang Pan, Feng Yang, Liucan Wang, Tianshu Yang, Guangsheng Du, Cong Xu, Hua Yang, Min Yu, Weidong Xiao
Article Number: 43
Published online on: 10 December 2025

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Review Open Access

Lactylation‑mediated ferroptosis: A novel mechanism and therapeutic prospects in human diseases (Review)

Zhengjun Lin, Yugang Zou, Songzhu Zou, Kunming Wen
Article Number: 42
Published online on: 08 December 2025

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Dual role of lactate in ferroptosis: Mechanisms, pathophysiology and therapeutic opportunities (Review)

Qian Yu, Yu Kuang, Jie He, Li Yang, Xinjie Li, Hao Yu
Article Number: 41
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] MicroRNA‑493‑5p promotes apoptosis and suppresses proliferation and invasion in liver cancer cells by targeting VAMP2

Guannan Wang, Xiaosan Fang, Meng Han, Xiaoming Wang, Qiang Huang
Article Number: 40
Published online on: 08 December 2025

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Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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Article Open Access

HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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Article Open Access

FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Review Open Access

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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