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Experimental and Therapeutic Medicine
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Print ISSN: 1792-0981 Online ISSN: 1792-1015
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-April 2010 Volume 1 Issue 2

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Impact Factor: 2.3

Article

Combinatorial intervention of prostaglandin E2 receptor and calcium sensing receptor to attenuate breast cancer cell proliferation, migration and bone metastasis (Review)

Jai Parkash, Kamlesh Asotra
Pages: 227-231
Published online on: 01 March 2010

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Article

Role of RGD-containing ligands in targeting cellular integrins: Applications for ovarian cancer virotherapy (Review)

Lena J. Gamble, Anton V. Borovjagin, Qiana L. Matthews
Pages: 233-240
Published online on: 01 March 2010

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Article

Dietary factors, genetic and epigenetic influences in colorectal cancer (Review)

M. L. Pellegrini, P. Argibay, D. E. Gomez
Pages: 241-250
Published online on: 01 March 2010

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Article

Novel strategy with acidic arginine solution for the treatment of influenza A virus infection (Review)

Keiko Ikeda, Hisashi Yamasaki, Yukiko Suzuki, A. Hajime Koyama, Tsutomu Arakawa
Pages: 251-256
Published online on: 01 March 2010

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Article

The use of Cox-2 and PPARγ signaling in anti-cancer therapies (Review)

Lucia Knopfová, Jan Šmarda
Pages: 257-264
Published online on: 01 March 2010

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Article Open Access

Curcumin for the prevention of progression in monoclonal gammopathy of undetermined significance: A word of caution (Review)

A. J.M. Vermorken, J. Zhu, W. J.M. van de Ven, Y. Cui, J. P. Fryns
Pages: 265-269
Published online on: 01 March 2010

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Article

EML4-ALK fusion transcripts in immunohistochemically ALK-positive non-small cell lung carcinomas

Kazuya Shinmura, Shinji Kageyama, Hisaki Igarashi, Takaharu Kamo, Takahiro Mochizuki, Kazuya Suzuki, Masayuki Tanahashi, Hiroshi Niwa, Hiroshi Ogawa, Haruhiko Sugimura
Pages: 271-275
Published online on: 01 March 2010

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Article

Deuterium-depleted water inhibits human lung carcinoma cell growth by apoptosis

Feng-Song Cong, Ya-Ru Zhang, Hong-Cai Sheng, Zong-Hua Ao, Su-Yi Zhang, Ju-Yong Wang
Pages: 277-283
Published online on: 01 March 2010

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Article

Macrophage involvement in Epstein-Barr virus-related tumors

Misuzu Shimakage, Haruhiko Sakamoto
Pages: 285-291
Published online on: 01 March 2010

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Article

Evaluation of the microvascular density in astrocytomas in adults correlated using SPECT-MIBI

Sandro Pantoja Cavalcante, José R.W. De Almeida, Carlos A. Clara, Cristovam Scapulatempo Neto, Stela Verzinhase Peres, Sônia M. Moriguchi, Marcelo J. Dos Santos, Euclides T. Da Rocha
Pages: 293-299
Published online on: 01 March 2010

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Article

Telmisartan inhibits human urological cancer cell growth through early apoptosis

Masahide Matsuyama, Kiyoaki Funao, Katsuyuki Kuratsukuri, Tomoaki Tanaka, Yutaka Kawahito, Hajime Sano, Jamel Chargui, Jean-Louis Touraine, Norio Yoshimura, Rikio Yoshimura
Pages: 301-306
Published online on: 01 March 2010

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Article

Electrolyte and protein imbalance following anti-EGFR therapy in cancer patients: A comparative study

Pius Maliakal, Andrea Ledford
Pages: 307-311
Published online on: 01 March 2010

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Article

Soluble mesothelin-related protein in pleural effusion from patients with malignant pleural mesothelioma

Nobukazu Fujimoto, Kenichi Gemba, Michiko Asano, Sae Wada, Katsuichiro Ono, Shinji Ozaki, Takumi Kishimoto
Pages: 313-317
Published online on: 01 March 2010

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Article Open Access

Combination of chemotherapy and mild hyperthermia enhances the anti-tumor effects of cisplatin and adriamycin in human bladder cancer T24 cells in vitro

Youko Itoh, Yoshiaki Yamada, Yoshiaki Kazaoka, Tsuneo Ishiguchi, Nobuaki Honda
Pages: 319-323
Published online on: 01 March 2010

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Article

Leucovorin and fluorouracil plus oxaliplatin or leucovorin and fluorouracil plus irinotecan as individualized first-line therapy based on a drug sensitivity test

Takumi Ochiai, Kazuhiko Nishimura, Tomoo Watanabe, Masayuki Kitajima, Tadasuke Hashiguchi, Akinori Nakatani, Takashi Marusasa, Akira Muraki, Isao Nagaoka, Shunji Futagawa
Pages: 325-329
Published online on: 01 March 2010

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Article

Gene expression and effects of orally active derivatives of fluoropyrimidine on gastric and colorectal cancer

Satoshi Arakawa, Soji Ozawa, Jin Kawase, Hisanori Oshima, Hidetoshi Nagata, Koji Atsuta, Shunji Umemoto
Pages: 331-336
Published online on: 01 March 2010

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Article

Effect of fibroblast growth factor-2 on periodontal ligament cells derived from human deciduous teeth in vitro

Tomokazu Hasegawa, Naoyuki Chosa, Takeyoshi Asakawa, Yoshitaka Yoshimura, Asami Asakawa, Akira Ishisaki, Mitsuro Tanaka
Pages: 337-341
Published online on: 01 March 2010

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Article

Clinical significance of hepatitis B virus-DNA in hepatocellular carcinoma negative for hepatitis B virus surface antigen

Shinpei Tateiwa, Yoshihiko Yano, Yasushi Seo, Akira Miki, Kawano Yuuki, Takeshi Azuma, Yoshitake Hayashi
Pages: 343-346
Published online on: 01 March 2010

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Article

Expression of epithelial-mesenchymal transition markers in locally recurrent hepatocellular carcinoma after radiofrequency ablation

Hidehiro Tajima, Tetsuo Ohta, Isamu Makino, Hironori Hayashi, Hisatoshi Nakagawara, Ichiro Onishi, Hiroyuki Takamura, Itasu Ninomiya, Hirohisa Kitagawa, Sachio Fushida, Takashi Tani, Takashi Fujimura, Masato Kayahara, Kuniaki Arai, Tatsuya Yamashita, Shuichi Kaneko, Yoh Zen
Pages: 347-350
Published online on: 01 March 2010

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Article

Role of inhibitor of DNA binding-1 protein is related to angiogenesis in the tumor advancement of uterine endometrial cancers

Min K. Maw, Jiro Fujimoto, Teruhiko Tamaya
Pages: 351-356
Published online on: 01 March 2010

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Article

Serological levels of mutated p53 protein are highly detected at early stages in breast cancer patients

Gabriela A. Balogh, Daniel Mailo, Hector Nardi, Maria M. Corte, Esteban Vincent, Elena Barutta, Guillermo Lizarraga, Pablo Lizarraga, Hector Montero, Roberto Gentili
Pages: 357-361
Published online on: 01 March 2010

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Article

Adenovirus Ad-p53AIP1-mediated gene therapy and its regulation of p53-MDM2 interactions

Yunbo Jiang, Huihua Chen, Haiquan Jia, Yuanji Xu, Gang Liu, Yan Wang, Xiaohe Yang, Yinglin Lu
Pages: 363-368
Published online on: 01 March 2010

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Article

Thymoquinone hydrazone derivatives cause cell cycle arrest in p53-competent colorectal cancer cells

André Wirries, Sandra Breyer, Karl Quint, Rainer Schobert, Matthias Ocker
Pages: 369-375
Published online on: 01 March 2010

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Article

Association of a polymorphism of ROR2 and ischemic stroke in Japanese individuals with chronic kidney disease

Mitsutoshi Oguri, Takanori Nagahiro, Haruo Kamiya, Miyoshi Ohno, Kimihiko Kato, Kiyoshi Yokoi, Tetsuro Yoshida, Sachiro Watanabe, Norifumi Metoki, Hidemi Yoshida, Kei Satoh, Yukitoshi Aoyagi, Yoshinori Nozawa, Yoshiji Yamada
Pages: 377-384
Published online on: 01 March 2010

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Article

Genetic and epigenetic alterations of RIZ1 and the correlation to clinicopathological parameters in liver fluke-related cholangiocarcinoma

Prasong Khaenam, Patcharee Jearanaikoon, Chawalit Pairojkul, Vajarabhongsa Bhudhisawasdi, Temduang Limpaiboon
Pages: 385-390
Published online on: 01 March 2010

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Article

Role of immunohistochemistry and apoptosis as investigative tools in assessing the prognosis of patients with prostate tumours

Srikumar Chakravarthi, P. M. Thani, David L.W. Yang, Linda T. Husin, Nagaraja Lee
Pages: 391-393
Published online on: 01 March 2010

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Article

Expression and tissue distribution of human X-linked armadillo repeat containing-6

Yusuke Kusama, Sayuri Takayanagi, Moe Tategu, Kenichi Yoshida
Pages: 395-399
Published online on: 01 March 2010

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Journal Cover
January-2026 Volume 31 Issue 1

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Impact Factor: 2.3

Article Open Access

Adiposity indices and bone health amongst Malaysian adults: Evidence from a cross‑sectional study

Wenjian Zhao, Weizheng Zhang, Kok-Yong Chin, Xiaodong Ma, Hashwin Singh Tejpal Singh, Sophia Ogechi Ekeuku, Yuanzhong Wang, Xia Ji, Yang Guo, Sok Kuan Wong, Norliza Muhammad, Teh Rohaila Jamil, Saharuddin Ahmad
Article Number: 28
Published online on: 21 November 2025

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Article Open Access

Ginsenoside Re attenuates homocysteine‑induced endothelial cell ferroptosis through upregulation of GPX4/xCT signaling

Shaolin Li, Chenge Zhao, Shengqin Yu, Kaijing Yang, Shuying Zhang, Sixu Liu
Article Number: 27
Published online on: 21 November 2025

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Case Report Open Access

Intussusception of the initial jejunum secondary to adenoma in the third and fourth portions of the duodenum: A case report

Lingbo Huo, Lixing Ma
Article Number: 26
Published online on: 21 November 2025

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Correction Open Access

[Corrigendum] Downregulation of DEC1 inhibits proliferation, migration and invasion, and induces apoptosis in ovarian cancer cells via regulation of Wnt/β‑catenin signaling pathway

Yun Yi, Bing Liao, Ziwen Zheng, Xiaorong Yang, Yunsheng Yang, Yanfang Zhou, Buzhen Tan, Xinfeng Yang
Article Number: 25
Published online on: 19 November 2025

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Article Open Access

Identification of early diagnostic biomarkers in venous thromboembolism: A bioinformatic analysis based on crosstalk between pyroptosis and venous thromboembolism

Shengbin Han, Jingzhe Xu, Chenchen Yu, Hongxi Guan, Shun Ding
Article Number: 24
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] Novel compound cedrelone inhibits hepatocellular carcinoma progression via PBLD and Ras/Rap1

Jiansong Wu, Qiang Niu, Jie Yuan, Xiaodan Xu, Liuxia Cao
Article Number: 23
Published online on: 17 November 2025

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Article Open Access

Atorvastatin ameliorates chronic subdural hematomas by interrupting the ‘chronic subdural hematoma cycle’ via inhibition of the inflammatory response

Jinqi Yan, Xiaohu Wang, Chen Liang
Article Number: 22
Published online on: 14 November 2025

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Review Open Access

Diagnosis and treatment of invasive fungal disease in children with hematological malignancies after chemotherapy: Challenges and strategies (Review)

Mingxin He, Feng Chen, Xiaomin Xian, Zhi Guo
Article Number: 21
Published online on: 14 November 2025

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Article Open Access

Venetoclax combined with azacitidine for treatment of a blastic plasmacytoid dendritic cell neoplasm: A case report and literature review

Yunching Lai, Xiaolei Chen, Hebing Zhou
Article Number: 20
Published online on: 10 November 2025

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Case Report Open Access

Diagnostic challenge of aneurysmal dermatofibroma mimicking cutaneous metastasis in a patient with lung cancer: A case report

Jong Yun Choi, Heeyang Park, Jangyoun Choi
Article Number: 19
Published online on: 10 November 2025

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Retraction Open Access

[Retracted] miRNA‑30d serves a critical function in colorectal cancer initiation, progression and invasion via directly targeting the GNA13 gene

Shan Muhammad, Qingchao Tang, Liu Wei, Qian Zhang, Guiyu Wang, Bilal Umar Muhammad, Kavanjit Kaur, Tatiana Kamchedalova, Zhao Gang, Zheng Jiang, Zheng Liu, Xishan Wang
Article Number: 18
Published online on: 10 November 2025

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Article

Leucine supplementation modulates lipid metabolism and metabolic pathways in mice with type 1 diabetes: A metabolomics study

Jeng-Yuan Yao, De-Tian-Yu Tzeng, Cai-Hong Feng, Gong-Man Xiao, Tian-Ni You, Ru-Yu Zheng
Article Number: 17
Published online on: 06 November 2025

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Case Report Open Access

Chronic maxillary sinusitis masquerading as a maxillary sinus neoplasm: A case report

Ji-Hyeon Oh, Seong-Gon Kim, Su-Young Kim
Article Number: 16
Published online on: 04 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑490‑3p regulates cell proliferation and apoptosis in gastric cancer via direct targeting of AKT1

Hong Yu, Jianying Sun, Shaochang Jiang, Ying Xu
Article Number: 15
Published online on: 04 November 2025

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Article Open Access

A comparison of bridging external fixation vs. combined external fixation for preventing radial height loss in older patients with distal radius fractures

Jingqiao Li, Yipeng Yang, Xu Zhang, Dandan Zhang, Yadong Yu, Rong Chen, Wei Du
Article Number: 14
Published online on: 30 October 2025

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Case Report Open Access

Primary epithelioid angiomatous nodule of the vocal cord: A case report and literature review

Keda Li, Bin Huang, Lubing Cai, Mingqi Huang, Jianping Shi, Mingdi Jin, Ning Qian, Yongkang Guo
Article Number: 13
Published online on: 29 October 2025

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Case Report Open Access

Hepatic perivascular epithelioid cell tumor: A rare mesenchymal tumor with epithelioid features: A case report

Mahmoud Abbas, Benjamin Strücker, Mehmet Haluk Morgül, Andreas Pascher, Wolfgang Hartmann, Eva Wardelmann
Article Number: 12
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Changes in the interstitial cells of Cajal in the gallbladder of guinea pigs fed a lithogenic diet

Lei Huang, Chao Ding, Xinmin Si
Article Number: 11
Published online on: 29 October 2025

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Article

Evaluation of total oxidant status/total antioxidant capacity and DNA damage in neonates with high lactate levels in umbilical cord blood gases

Burcu Cebeci, Aydemir Yalvaç, Derya Büyükkayhan, Dilek Kurnaz, Hakan Çakir, Murat Elevli
Article Number: 10
Published online on: 29 October 2025

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Case Report

Treatment of a mandibular molar with primary failure of eruption: A case report

Ming Guo, Weisheng Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

Effect of the water‑soluble matrix of nanometer pearl powder on the osteogenic differentiation of hFOB1.19 cells

Xinghuanyu Xu, Lin Liu, Wenbai Zhang, Pu Xu
Article Number: 8
Published online on: 29 October 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA phosphatase and tensin homolog pseudogene 1 suppresses osteosarcoma cell growth via the phosphoinositide 3‑kinase/protein kinase B signaling pathway

Bin Yan, Aikepaer Wubuli, Yidong Liu, Xin Wang
Article Number: 7
Published online on: 27 October 2025

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Article Open Access

Diagnostic significance of the checkpoint kinase 1 gene in high‑grade gastroenteropancreatic neuroendocrine neoplasms

Na Li, Jianduo An, Yanping Hu
Article Number: 6
Published online on: 24 October 2025

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Retraction Open Access

[Retracted] Establishment of ApoE‑knockout mouse model of preeclampsia and relevant mechanisms

Wenjuan Sun, Baoxia Cui, Fanzhen Hong, Yongping Xu
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Investigating the association between uterine fibroids and weight‑bearing joint osteoarthritis based on a bidirectional Mendelian randomization study

Xiao Ma, Jingjing Ma, Han Zhang, Xiaodong Jia, Tianrui Wang, Shanshan Ma, Yingze Zhang
Article Number: 4
Published online on: 21 October 2025

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Article Open Access

Epimedin C: A promising neuroprotective agent that can participate in mediating the JNK/Nrf2/HO‑1 signaling pathway to prevent neurodegenerative diseases

Chao Cong, Xuan-Ling Li, Guang-Yao Lin, Lian-Wei Xu
Article Number: 3
Published online on: 21 October 2025

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Article Open Access

Application of pleural effusion cell blocks for immunohistochemistry and EGFR gene mutation testing for advanced lung cancer

Shouxiang Zhao, Yuhong Liu, Tao Wang, Ying Li, Ze Chen, Xiaoshan Cai
Article Number: 2
Published online on: 21 October 2025

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Correction Open Access

[Corrigendum] Evaluation of the inhibitory effects of vaginal microorganisms on sperm motility in vitro

Huan Wang, Tingtao Chen, Yidan Chen, Tao Luo, Buzhen Tan, Houyang Chen, Hongbo Xin
Article Number: 1
Published online on: 16 October 2025

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Journal Cover
February-2026 Volume 31 Issue 2

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Impact Factor: 2.3

Case Report Open Access

Appendiceal mucinous tumour resulting in autoamputation of the appendix: A case report and literature review

Chenao Wang, Yufeng Liu, Yaqing Liu, Baicheng Li, Xingdong Hou, Bowei Lu, Zhao Chen, Shili Ning
Article Number: 48
Published online on: 05 December 2025

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Case Report Open Access

Calcifying fibrous tumours of the diaphragm: A case report and literature review

Sijia Guo, Wenya Han, Lingling Yuan, Hansheng Wang, Ge Cheng, Yaxin Tuo, Chuanyong Xiao, Jialong Guo, Meifang Wang
Article Number: 47
Published online on: 05 December 2025

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Case Report

Prolonged remission of SAPHO syndrome with low‑dose leflunomide: A case report and literature review

Angelo Nigro
Article Number: 46
Published online on: 05 December 2025

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Correction Open Access

[Corrigendum] Effects of matrine on the proliferation and apoptosis of vincristine‑resistant retinoblastoma cells

Bowen Zhao, Bin Li, Qian Liu, Fei Gao, Zhibao Zhang, Haixia Bai, Yichen Wang
Article Number: 45
Published online on: 04 December 2025

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Article Open Access

Efficacy of nerve blocks for postoperative analgesia in lung cancer: A meta‑analysis of randomized clinical trials

Jie Wu, Yu-Xin Liu, Shipeng Zhang, Baiping An
Article Number: 44
Published online on: 03 December 2025

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Article

Prenatally diagnosed intra‑abdominal testicular teratoma managed with single‑stage Fowler‑Stephens orchiopexy postnatally: A case report and literature review

Honggang Fang, Guangbei Peng, Xing Liu, Shengde Wu, Yi Hua, Guanghui Wei, Deying Zhang
Article Number: 43
Published online on: 02 December 2025

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Review

Plazomicin: A promising novel antimicrobial in the era of bacterial resistance (Review)

Mohamed Abouelkheir, Ahmed E. Taha, Ibrahim A. Taher, Heba M. Saad Eldien, Gamal Abdelrahman Bakhaat
Article Number: 42
Published online on: 02 December 2025

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Case Report

A novel presentation of minocycline‑induced nail discoloration: A case report

Ke Li, Wenjing Zha, Yitao Qian, Lei Shi
Article Number: 41
Published online on: 01 December 2025

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Published online on: 01 December 2025

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Published online on: 01 December 2025

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Published online on: 01 December 2025

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Mammalian target of rapamycin inhibitors as the treatment for steroid‑refractory acute graft‑vs.‑host disease after allogeneic hematopoietic stem cell transplantation: A systematic review and individual patient data meta‑analysis

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Published online on: 01 December 2025

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Published online on: 28 November 2025

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Liuniu Xiao, Xiao Ran, Shusheng Li
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Published online on: 28 November 2025

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Published online on: 28 November 2025

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Pan‑cancer analysis of the oncogenic role of SRY‑related high‑mobility group box protein B5 in human tumors

Yajun Tong, Huini Da, Kewei Tang, Qiang Zhou, Songlian Liu, Leilan Yin, Ling Long, Site Bai, Ludi Ou, Qinghua Yin
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Published online on: 28 November 2025

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Inhibition of sclerostin activity promotes bone regeneration in experimental periodontal disease: A systematic review and meta‑analysis of animal models

Miaomiao Yang, Yongqing Ma, Xiaofu Qu, Zhe Qu, Jiang Sun
Article Number: 31
Published online on: 25 November 2025

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Effect of enhanced recovery after surgery‑based perioperative nursing on postoperative pain and recovery in patients with cervical cancer: A retrospective cohort study

Lu Mo, Ruichen Liang, Xianyong Wang, Zhiwei Xiao, Zhongxun Wu, Lihong Chen
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Published online on: 25 November 2025

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Expression of Concern Open Access

[Expression of Concern] Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate‑resistant polycystic ovary syndrome

Wei Liu, Shengnan Dong, Yumei Li, Lihong Shi, Wei Zhou, Yingling Liu, Jie Liu, Yazhong Ji
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Published online on: 24 November 2025

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