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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August 2003 Volume 12 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Detailed Hylobates lar karyotype defined by 25-color FISH and multicolor banding

Kristin Mrasek, Anita Heller, Nikolai Rubtsov, Vladimir Trifonov, Heike Starke, Uwe Claussen, Thomas Liehr
Pages: 139-146
Published online on: 01 August 2003

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Article

Sesquiterpenes (costunolide and zaluzanin D) isolated from laurel (Laurus nobilis L.) induce cell death and morphological change indicative of apoptotic chromatin condensation in leukemia HL-60 cells

Hiroshige Hibasami, Yayoi Yamada, Hiroyuki Moteki, Hirotaka Katsuzaki, Kunio Imai, Kazumi Yoshioka, Takashi Komiya
Pages: 147-151
Published online on: 01 August 2003

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Article

PARP inhibition improves the effectiveness of neural stem cell transplantation in experimental brain trauma

Zsombor Lacza, Eszter M. Horváth, Katalin Komjáti, Tibor Hortobágyi, Csaba Szabó, David W. Busija
Pages: 153-159
Published online on: 01 August 2003

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Article

Cloning and characterization of a novel splicing isoform of USF1

Tomoko Saito, Takayuki Oishi, Kazuyuki Yanai, Yoko Shimamoto, Akiyoshi Fukamizu
Pages: 161-167
Published online on: 01 August 2003

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Article

Somatic mutation of mitochondrial DNA in Helicobacter pylori-associated chronic gastritis in patients with and without gastric cancer

Toru Hiyama, Shinji Tanaka, Hideyuki Shima, Kazuhiro Kose, Yasuhiko Kitadai, Masanori Ito, Masaharu Sumii, Masaharu Yoshihara, Fumio Shimamoto, Ken Haruma, Kazuaki Chayama
Pages: 169-174
Published online on: 01 August 2003

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Article

Aromatic residues are required for RNA helicase A mediated transactivation

Satoko Aratani, Ryouji Fujii, Hidetoshi Fujita, Akiyoshi Fukamizu, Toshihiro Nakajima
Pages: 175-180
Published online on: 01 August 2003

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Article

Differential expression of proteins of caspases and Bcl-2 families in the brain of mice

Se H. Min, Dae Y. Hwang, Tae S. Kang, Jin H. Hwang, Chae H. Lim, Su H. Lee, Hwa J. Lim, Su J. Seo, Yhun Y. Sheen, Sang G. Paik, Jung S. Cho, Yong K. Kim
Pages: 181-183
Published online on: 01 August 2003

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Article

A novel single-nucleotide substitution, Leu 467 Pro, in the interferon-γ receptor 1 gene associated with allergic diseases

Minako Aoki, Eiko Matsui, Hideo Kaneko, Ryosuke Inoue, Toshiyuki Fukao, Mizuho Watanabe, Takahide Teramoto, Zenichiro Kato, Kiyotaka Suzuki, Yasuyuki Suzuki, Kimiko Kasahara, Naomi Kondo
Pages: 185-191
Published online on: 01 August 2003

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Article

Relative abundance and patterns of correlation among six cytokines in pleural fluid measured by cytometric bead array

Keisuke Aoe, Akio Hiraki, Tomoyuki Murakami, Kazuo Murakami, Kiyoshi Makihata, Kazushi Takao, Ryosuke Eda, Tadashi Maeda, Kazuro Sugi, Zbigniew Darzynkiewicz, Hiroyasu Takeyama
Pages: 193-198
Published online on: 01 August 2003

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Article

Alteration of α-amylase secretion from rat parotid cells in the absence of extracellular bicarbonate

Rahali Youssef, Willy J. Malaisse, Philippe Courtois, Abdullah Sener
Pages: 199-200
Published online on: 01 August 2003

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Article

Regulatory effect of regucalcin on nitric oxide synthase activity in rat kidney cortex cytosol: Role of endogenous regucalcin in transgenic rats

Zhong Jie Ma, Masayoshi Yamaguchi
Pages: 201-206
Published online on: 01 August 2003

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Role of endogenous regucalcin in transgenic rats: Suppression of protein tyrosine phosphatase and ribonucleic acid synthesis activities in liver nucleus

Yoshinori Tsurusaki, Masayoshi Yamaguchi
Pages: 207-211
Published online on: 01 August 2003

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Article

Ghrelin, an endogenous ligand for the growth hormone-secretagogue receptor, is expressed in the human adrenal cortex

Cinzia Tortorella, Carlo Macchi, Raffaella Spinazzi, Ludwik K. Malendowicz, Marcin trejter, Gastone G. Nussdorfer
Pages: 213-217
Published online on: 01 August 2003

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Article

Cytogenetic and molecular genetic changes in malignant transformation of immortalized esophageal epithelial cells

Zhong-Ying Shen, Li-Yan Xu, Min-Hua Chen, Wei-Jia Cai, Jian Shen, Jiong-Yu Chen, Yi Zeng
Pages: 219-224
Published online on: 01 August 2003

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Article

Autoantibodies against muscarinic cholinergic receptor in chronic fatigue syndrome

Susumu Tanaka, Hirohiko Kuratsune, Yoh Hidaka, Yukiko Hakariya, Ke-Ita Tatsumi, Toru Takano, Yuzuru Kanakura, Nobuyuki Amino
Pages: 225-230
Published online on: 01 August 2003

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Article

The gene expression profile of human umbilical vein endothelial cells stimulated with lipopolysaccharide using cDNA microarray analysis

Sung K. Ahn, Tae-Boo Choe, Tae-Jong Kwon
Pages: 231-236
Published online on: 01 August 2003

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Article

Exendin-4, a GLP-1 receptor agonist, stimulates pituitary-adrenocortical axis in the rat: Investigations into the mechanism(s) underlying Ex4 effect

Ludwik K. Malendowicz, Gastone G. Nussdorfer, Krzysztof W. Nowak, Agnieszka Ziolkowska, Cinzia Tortorella, Marcin Trejter
Pages: 237-241
Published online on: 01 August 2003

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Article

Use of real-time RT-PCR for the detection of allelic expression of an imprinted gene

Tetsuji Suda, Motonobu Katoh, Masaharu Hiratsuka, Mutsunori Fujiwara, Yoshito Irizawa, Mitsuo Oshimura
Pages: 243-246
Published online on: 01 August 2003

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Article

Association of mitochondrial calpain activation with increased expression and autolysis of calpain small subunit in an early stage of apoptosis

Kenyon G. Daniel, Johnathan S. Anderson, Qing Zhong, Aslamuzzaman Kazi, Puja Gupta, Q. Ping Dou
Pages: 247-252
Published online on: 01 August 2003

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Expression of human delta-6-desaturase is associated with aggressiveness of human breast cancer

Jane Lane, Robert E. Mansel, Wen G. Jiang
Pages: 253-257
Published online on: 01 August 2003

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Article

Identification of a new GLC1A mutation in a sporadic, primary open-angle glaucoma in Japan

Takayuki Ikezoe, Seisho Takeuchit, Naoki Komatsu, Miyuki Okada, Atsuki Fukushima, Hisayuki Ueno, H. Phillip Koeffler, Hirokuni Taguchi
Pages: 259-261
Published online on: 01 August 2003

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Article

Identification and characterization of mouse Ppfia1 gene in silico

Masuko Katoh, Masaru Katoh
Pages: 263-267
Published online on: 01 August 2003

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Article

Anti-angiogenic potential of Gleditsia sinensis fruit extract

Larry Ming Cheung Chow, Chung Hin Chui, Johnny Cheuk On Tang, Fung Yi Lau, Mabel Yin Chun Yau, Gregory Yin Ming Cheng, Raymond Siu Ming Wong, Paul Bo San Lai, Thomas Wai Tong Leung, Ivy Tuang Ngo Teo, Filly Cheung, Dean Guo, Albert Sun Chi Chan
Pages: 269-273
Published online on: 01 August 2003

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Macrophage SH3 domain‑containing GRB2‑like protein B1 is required for Rab7‑mediated mitophagy in inflammation during sea water drowning acute lung injury

Hongjuan Ning, Jingyu Deng, Yongheng Gao, Wei Zhang, Jian Chen, Xian Guo, Faguang Jin
Article Number: 138
Published online on: 24 March 2026

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Deferoxamine mitigates neuronal loss following spinal cord injury via ferroptosis inhibition and Nrf2/HO‑1 pathway activation

Ziqian Ma, Xinwei Zhang, Tao Liu, Yan Zhang, Guanghao Li, Xin Yuan, Benqiang Tang, Hangyi Zhao, Liang Liu, Xueming Chen
Article Number: 137
Published online on: 23 March 2026

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Review Open Access

USP10 deubiquitinase: Physiological function, diseases and therapeutic target (Review)

Linlin Zhang, Huajing Sun, Zifan Wang, Zhimei Wang, Qiang Mu, Yukun Liu
Article Number: 136
Published online on: 23 March 2026

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Siglec‑15 dysregulation and its therapeutic implications in new‑onset type 1 diabetes 

Heming Guo, Yunwen Tao, Sicheng Li, Ying Gu, Yiting Huang, Chen Fang, Ji Hu
Article Number: 135
Published online on: 20 March 2026

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ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing

Yan Zhao, Yuankai Zhang, Tian Lei, Shangqing Zhang, Kai Nan, Xin Zhang, Li-Hong Fan
Article Number: 134
Published online on: 19 March 2026

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Targeting pyroptosis in renal fibrosis: From molecular mechanisms to therapeutic horizons (Review)

Yihuai Tian, Quwu Mushuo, Hui Fan, Hongwei Su, Jianchun Li, Qiong Zhang
Article Number: 133
Published online on: 19 March 2026

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Expression of Concern Open Access

[Expression of Concern] Fasudil, a Rho‑associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats

Haishan Song, Dianwen Gao
Article Number: 132
Published online on: 18 March 2026

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Review Open Access

Epigenetic regulation in a high-sugar environment (Review)

Huili Zhou, Xinhe Lv, Yu Liang, Dehai Yu, Wanning Wang
Article Number: 131
Published online on: 17 March 2026

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Review Open Access

The roles and heterogeneity of CD8+ T cells in inflammatory bowel disease: A narrative review of insights from single‑cell transcriptomics (Review)

Rui Zhong, Jing Guo, Wujie Ye, Zhihui Deng, Huangan Wu, Qin Qi, Guona Li, Lu Zhu, Yan Huang, Luyi Wu
Article Number: 130
Published online on: 17 March 2026

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Mechanism of action and clinical application of autophagy in multiple sclerosis (Review)

Dongmei Wang, Qizhi Fu, Ying Zhao, Guangda Li, Yongjie Bai, Yang Yang, Hongna Song, Mingwei Wang, Hua Fan
Article Number: 129
Published online on: 17 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation

Mamiko Hie, Natsumi Iitsuka, Tomoyo Otsuka, Ikuyo Tsukamoto
Article Number: 128
Published online on: 16 March 2026

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Mechanotransduction and its impact on regenerative medicine in orthopedic rehabilitation (Review)

Baohui Wang, Xueqin Zeng, Huajian Liu, Liang Li, Tao Lei, Yafeng Li, Qing Fang, Yi Cao, Bo Dong
Article Number: 127
Published online on: 13 March 2026

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4‑Acetylantrocamol LT3 suppresses colorectal cancer growth and metastasis via PI3K/AKT and MAPK pathway modulation

Kuen-Tze Lin, Yu-Chieh Hsieh, Pi-Kai Chang, Chih-Wei Lai, Shih-Yu Lee, I-Chuan Yen
Article Number: 126
Published online on: 13 March 2026

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Roles of ubiquitin‑specific peptidase 22 in cellular fate: From embryonic survival to tissue repair, inflammation and metabolism (Review)

Jia-Nan Xiang, Chen-Yang Zhou, Yu-Di Zhao, Xiao Xu, Sun-Bin Ling
Article Number: 125
Published online on: 12 March 2026

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m6A in adipose tissue inflammation: A novel regulator of obesity and metabolic diseases (Review)

Xiaoting Yang, Xiaodan Wang, Haojun Tang, Shuangxi Tu, Kai Yin, Xiao Zhu
Article Number: 124
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Visfatin/PBEF/Nampt induces EMMPRIN and MMP‑9 production in macrophages via the NAMPT‑MAPK (p38, ERK1/2)‑NF‑κB signaling pathway

Yuqi Fan, Shu Meng, Yue Wang, Jiatian Cao, Changqian Wang
Article Number: 123
Published online on: 12 March 2026

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IL‑37/IL‑1R8 blocks keratinocyte acantholysis via suppressing ADAM17/EGFR

Fengxia Hu, Wenjing Chen, Qian Wang, Xiaoyu Zhang, Fuyang Xiao, Jinying Zhang, Junqin Liang
Article Number: 122
Published online on: 12 March 2026

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Reactive oxygen species in fetal growth restriction mechanisms and therapeutic directions (Review)

Di Cheng, Songbin Yang, Cuilan Wang, Kefeng Fan, Fengchun Gao, Qian Sun
Article Number: 121
Published online on: 12 March 2026

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Research progress on the molecular mechanisms of tanshinone IIA in the treatment of cardiovascular and cerebrovascular diseases (Review)

Wen Pei, Ping Lu, Chenhuan Ding, Ying Li, Yong Li
Article Number: 120
Published online on: 12 March 2026

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Ferritin in ferroptosis: Implications for neurodegenerative diseases (Review)

Wenjing Chen, Heng Tian, Ran Wei, Xiaomei Chen, Yiwen Jia
Article Number: 119
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling  

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang
Article Number: 118
Published online on: 09 March 2026

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Article Open Access

HELLS inhibits autophagy‑dependent ferroptosis in nasopharyngeal carcinoma by modulating the Nrf2/HO‑1/GPX4 pathway

Chengxun Jin, Jinqiu Li, Siqi Han, Chaoluomeng Bai, Jingpu Yang, Zonggui Wang
Article Number: 117
Published online on: 09 March 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis

Ying Zhang, Hong Cao, Yue-Yue Hu, Hua Wang, Chang-Jun Zhang
Article Number: 116
Published online on: 09 March 2026

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Article Open Access

Propofol upregulates MFG‑E8 in BV2 cells to inhibit pyroptosis mediated by the NF‑κB/NLRP3 pathway, thereby ameliorating ischemic‑reperfusion neuronal injury

Shewei Guo, Yingwei Zhen, Guosheng Zhou, Zhihua Zhao
Article Number: 115
Published online on: 05 March 2026

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Article Open Access

Exosomal circ0000549 promotes MNNG‑induced gastric cancer through miR‑15b‑5p/KIF1B

Zhaofeng Liang, Zihan Gao, Yue Zhang, Jiajia Song, Hui Qian, Xuezhong Xu
Article Number: 114
Published online on: 04 March 2026

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Expression of Concern Open Access

[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy  

Fangfang Li, Ning Zhang, Qingqing Wu, Yuan Yuan, Zheng Yang, Mengqiao Zhou, Jinxiu Zhu, Qizhu Tang
Article Number: 113
Published online on: 04 March 2026

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Review Open Access

Treatment of pulmonary fibrosis: From disease mechanisms to future novel therapies (Review)

Sen Lu, Yunfei Liu, Xiaohua Li, Qipeng Yao
Article Number: 112
Published online on: 03 March 2026

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Research progress in single‑cell omics technologies for kidney disease (Review)

Jia Xu, Ziwei Chen, Shengyao Li, Xiaoya Wang, Ming Chen
Article Number: 111
Published online on: 03 March 2026

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CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review)

Xiuping Lai, Yan Yan, Lu Sun, Zili Lei, Yanhong Yang
Article Number: 110
Published online on: 03 March 2026

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Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)

Sen Lu, Jiale Tong, Jing Jiang, Qin Zhang, Youjin Huang
Article Number: 109
Published online on: 03 March 2026

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Review Open Access

The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)

Yingying Zhang, Ruxin Shen
Article Number: 108
Published online on: 02 March 2026

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Review Open Access

Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

Bojiao Yang, Feng Li, Guimao Cao, Mingtu Nuo, Yaxin Shi, Zilu Wang, Jing Jia, Wei Shi, Zhiyong Liu
Article Number: 107
Published online on: 02 March 2026

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Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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Journal Cover
June-2026 Volume 57 Issue 6

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Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Role of itaconate in intestinal disease (Review)

Xin Li, Qian Liu, Jiajia Li, Li Zhang, Shun Yao, Lulu Tang, Bingqi Yang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 144
Published online on: 27 March 2026

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Unveiling lactylation: A novel frontier in the pathogenesis of diabetic nephropathy (Review)

Yuanyuan Xiao, Niansong Wang, Dingkun Gui, Youhua Xu
Article Number: 143
Published online on: 27 March 2026

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Review Open Access

Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
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Expression of Concern Open Access

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