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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2004 Volume 14 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Cytogenetic characterization of seven human cancer cell lines by combining G- and R-banding, M-FISH, CGH and chromosome- and locus-specific FISH

Michèle Cottier, Andrei Tchirkov, Bernard Perissel, Michel Giollant, Lydia Campos, Philippe Vago
Pages: 483-495
Published online on: 01 October 2004

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Article

The influence of neural signal transduction on EEC gene expression under consideration of chromatin, following myenteric ablation (review).

G E Holle
Pages: 497-1001
Published online on: 01 October 2004

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Article

Expression of interleukin-6 in human craniopharyngiomas: a possible inducer of tumor-associated inflammation.

Masanao Mori, Hideo Takeshima, Jun-ichi Kuratsu
Pages: 505-514
Published online on: 01 October 2004

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Article

Acellular liver matrix improves the survival and functions of isolated rat hepatocytes cultured in vitro.

Patrizia Burra, Silvia Tomat, Maria Teresa Conconi, Carlo Macchi, Francesco P Russo, Pier Paolo Parnigotto, Remo Naccarato, Gastone G Nussdorfer
Pages: 511-516
Published online on: 01 October 2004

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Article

CD82, and CD63 in thyroid cancer.

Zhouxun Chen, Tarek Mustafa, Bogusz Trojanowicz, Michael Brauckhoff, Oliver Gimm, Cornelia Schmutzler, Josef Köhrle, Hans-Jürgen Holzhausen, Astrid Kehlen, Thomas Klonisch, Rainer Finke, Henning Dralle, Cuong Hoang-Vu
Pages: 517-544
Published online on: 01 October 2004

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Article

Tumor targeting by doxorubicin-RGD-4C peptide conjugate in an orthotopic mouse hepatoma model.

Jin-Wook Kim, Hyo-Suk Lee
Pages: 529-564
Published online on: 01 October 2004

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Article

Stress deprivation enhances manganese superoxide dismutase expression in the rat patellar tendon.

Nobuto Kitamura, Harukazu Tohyama, Jun Nishihira, Motoko Hatano, Masaki Suzuki, Kazunori Yasuda
Pages: 537-580
Published online on: 01 October 2004

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Article

Experimental gene therapy using p21Waf1 gene for esophageal squamous cell carcinoma by gene gun technology.

Yuichi Tanaka, Teruhiko Fujii, Hideaki Yamana, Seiya Kato, Minoru Morimatsu, Kazuo Shirouzu
Pages: 545-596
Published online on: 01 October 2004

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Article

Proteomic analysis finds different myocardial protective mechanisms for median nerve stimulation by electroacupuncture and by local somatothermal stimulation.

Meng-Ting Tsou, Jin-Yuan Ho, Chao-Hsiung Lin, Jen-Hwey Chiu
Pages: 553-616
Published online on: 01 October 2004

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Article

Cyclooxygenase-2 in human malignant fibrous histiocytoma: correlations with intratumoral microvessel density, expression of vascular endothelial growth factor and thymidine phosphorylase.

Hideki Yamashita, Mitsuhiko Osaki, Tonang Dwi Ardyanto, Mari Osaki, Haruhiko Yoshida, Hisao Ito
Pages: 565-635
Published online on: 01 October 2004

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Article

Tumor secreting high levels of IL-15 induces specific immunity to low immunogenic colon adenocarcinoma via CD8+ T cells.

Atsuhiro Araki, Shoichi Hazama, Kiyoshi Yoshimura, Shigefumi Yoshino, Norio Iizuka, Masaaki Oka
Pages: 571-577
Published online on: 01 October 2004

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Article

Mutational, epigenetic and expressional analyses of caveolin-1 gene in breast cancers.

Shou-Tung Chen, Syh-Yi Lin, Kun-Tu Yeh, Shou-Jen Kuo, Wen-Ling Chan, Yen-Ping Chu, Jan-Gowth Chang
Pages: 577-659
Published online on: 01 October 2004

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Article

Expression and regulation of RB1CC1 in developing murine and human tissues.

Noriko Bamba, Tokuhiro Chano, Takashi Taga, Shigeru Ohta, Yoshihiro Takeuchi, Hidetoshi Okabe
Pages: 583-590
Published online on: 01 October 2004

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Article

Targeting TGF-beta in human keratinocytes and its potential role in wound healing.

Katrin Philipp, Frank Riedel, Michael Sauerbier, Karl Hörmann, Günter Germann
Pages: 589-682
Published online on: 01 October 2004

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Article

Persisted/recurrent hyperparathyroidism associated with development of multi-drug resistance phenotype and proliferation of parathyroid transplants.

Tomasz Grzela, Witold Chudzinski, Maciej Lazarczyk, Justyna Niderla, Piotr Dziunycz, Lukasz Milewski, Robert Samaha, Malgorzata Kobylecka, Joanna Miskiewicz, Elzbieta Bogacka-Zatorska, Barbara Gornicka, Pawel Swiercz, Magdalena Jelenska, Leszek Krolicki
Pages: 595-604
Published online on: 01 October 2004

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Article

External auditory canal cholesteatoma: analysis of the integrity of the tissue structure.

Ramin Naim, Haneen Sadick, Carsten Schafer, Karl Hormann
Pages: 601-605
Published online on: 01 October 2004

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Article

Expression of hnRNP A2/B1 proteins in small airway epithelial cells.

Hiroaki Satoh, Hiroichi Ishikawa, Hiroshi Kamma, Masachika Fujiwara, Shinsuke Homma, Katsunori Kagohashi, Morio Ohtsuka, Kiyohisa Sekizawa
Pages: 605-613
Published online on: 01 October 2004

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Article

Apolipoprotein E as vascular risk factor in neurodegenerative dementia.

Marcella Folin, Silvia Baiguera, Maria Teresa Conconi, Rosa Di Liddo, Eugenio De Carlo, Pier Paolo Parnigotto, Gastone G Nussdorfer
Pages: 609-622
Published online on: 01 October 2004

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Article

Peribronchial innervation of the rat lung.

Marco Artico, Sandro Bosco, Elena Bronzetti, Laura M Felici, Giuseppe Pelusi, Vincenza Rita Lo Vasco, Marco Vitale
Pages: 615-635
Published online on: 01 October 2004

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Article

Natriuretic peptides up-regulate aquaporin 3 in a human colonic epithelial cell line.

Akihiko Itoh, Tomoyuki Tsujikawa, Takashi Yasuoka, Tamio Nakahara, Masaya Sasaki, Yoshihide Fujiyama
Pages: 621-627
Published online on: 01 October 2004

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Article

Baicalein induces apoptosis through ROS-mediated mitochondrial dysfunction pathway in HL-60 cells.

Jianwu Wang, Yuanjing Yu, Fumio Hashimoto, Yusuke Sakata, Makoto Fujii, De-Xing Hou
Pages: 627-659
Published online on: 01 October 2004

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Article

Hypoxia-induced renal epithelial cell death through caspase-dependent pathway: role of Bcl-2, Bcl-xL and Bax in tubular injury.

Kei Yamamoto, Naruya Tomita, Shin-ichi Yoshimura, Hironori Nakagami, Yoshiaki Taniyama, Keita Yamasaki, Toshio Ogihara, Ryuichi Morishita
Pages: 633-673
Published online on: 01 October 2004

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Article

Role of Us3 gene of herpes simplex virus type 1 for resistance to interferon.

Ahmad Piroozmand, A Hajime Koyama, Yoshiko Shimada, Mikako Fujita, Tsutomu Arakawa, Akio Adachi
Pages: 641-646
Published online on: 01 October 2004

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Article

Hyperlipidemia is induced in regucalcin transgenic rats with increasing age.

Masayoshi Yamaguchi, Aki Igarashi, Satoshi Uchiyama, Natsumi Sawada
Pages: 647-698
Published online on: 01 October 2004

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Article

Insulin resistance in thermally-injured rats is associated with post-receptor alterations in skeletal muscle, liver and adipose tissue.

Edward A Carter, Deborah Burks, Alan J Fischman, Morris White, Ronald G Tompkins
Pages: 653-661
Published online on: 01 October 2004

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Article

Increase in metalloproteinase activity in the plasma of smoke-extract-injected rats.

Toshio Machida, Motoo Kubota, Naokatsu Saeki, Masaki Takiguchi, Akira Yamaura, Takaki Hiwasa
Pages: 659-721
Published online on: 01 October 2004

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Article

Expression of CYP3A4 by an immortalized human hepatocyte line in a three-dimensional culture using a radial-flow bioreactor.

Ichiro Akiyama, Koji Tomiyama, Masakiyo Sakaguchi, Mikiro Takaishi, Masaharu Mori, Masakiyo Hosokawa, Seishi Nagamori, Nobuyoshi Shimizu, Nam-Ho Huh, Masahiro Miyazaki
Pages: 663-671
Published online on: 01 October 2004

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Article

Effects of genetic and nutritional factors on bone mineral density in young adults.

Takemi Otsuki, Haruko Sakaguchi, Emiko Hatta, Tamayo Hatayama, Satomi Hatada, Yoshie Miura, Akiko Takata-Tomokuni, Fuminori Hyodoh, Tatsushi Tomomitsu, Masao Fukunaga, Hironobu Katsuyama
Pages: 669-745
Published online on: 01 October 2004

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Article

Mathematical modelling of alpha- and beta-D-glucose metabolism in pancreatic islets exposed to equilibrated D-glucose.

Willy J Malaisse, Abdullah Sener
Pages: 677-759
Published online on: 01 October 2004

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Article

ASA E382K disrupts a potential exonic splicing enhancer and causes exon skipping, but missense mutations in ASA are not associated with ESEs.

Vorasuk Shotelersuk, Tayard Desudchit, Siraprapa Tongkobpetch
Pages: 683-692
Published online on: 01 October 2004

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Article

Regucalcin increases superoxide dismutase activity in the heart cytosol of normal and regucalcin transgenic rats.

Emiko Ichikawa, Masayoshi Yamaguchi
Pages: 691-696
Published online on: 01 October 2004

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Article

Bax is an important determinant for radiation sensitivity in esophageal carcinoma cells.

Ryungsa Kim, Hideki Inoue, Tetsuya Toge
Pages: 697-1403
Published online on: 01 October 2004

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Article

Suppression of angiogenic activity of sera from diabetic patients with non-proliferative retinopathy by compounds of herbal origin and sulindac sulfone.

Piotr Skopinski, Jerzy Szaflik, Barbara Duda-Król, Jadwiga Nartowska, Ewa Sommer, Joanna Chorostowska-Wynimko, Urszula Demkow, Ewa Skopinska-Rózewska
Pages: 707-718
Published online on: 01 October 2004

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Article

Non-viral tumor necrosis factor-alpha gene transfer decreases the incidence of orthotopic bladder tumors.

Zhijiang Zang, Ratha Mahendran, Qinghui Wu, Thomas Yong, Kesavan Esuvaranathan
Pages: 713-720
Published online on: 01 October 2004

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Article

Effect of c-ski overexpression on the development of cachexia in mice bearing the Lewis lung carcinoma.

Neus Carbó, Paola Costelli, Sílvia Busquets, Joaquín López-Soriano, Francisco J López-Soriano, Francesco M Baccino, Josep M Argilés
Pages: 719-742
Published online on: 01 October 2004

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Article

Influence of pentoxifylline on perforin expression in human PBMC.

Maciej Lazarczyk, Tomasz Grzela, Justyna Niderla, Piotr Dziunycz, Lukasz Milewski, Marta Alicja Lazarczyk, Robert Samaha
Pages: 725-733
Published online on: 01 October 2004

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Article

Construction of phage display libraries from reactive lymph nodes of breast carcinoma patients and selection for specifically binding human single chain Fv on cell lines.

A Rothe, A Klimka, M K Tur, T Pfitzner, M Huhn, S Sasse, P Mallmann, A Engert, S Barth
Pages: 729-764
Published online on: 01 October 2004

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Article

Limited specificity of promoter constructs for gene therapy in osteosarcoma.

Annika Pollmann, Hartmut Kabisch, Andreas Block, Jürgen Müller, Olaf J C Hellwinkel
Pages: 737-779
Published online on: 01 October 2004

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Article

Sex chromosome rearrangements leading to partial aneuploidies and mosaicisms: use of QF-PCR for detection and quantification of the involved cell lines.

Angela Elvira Covone, Gianfranco Voglino, Roberto Ravazzolo
Pages: 743-749
Published online on: 01 October 2004

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Article

Identification and characterization of human HESL, rat Hesl and rainbow trout hesl genes in silico.

Masuko Katoh, Masaru Katoh
Pages: 747-798
Published online on: 01 October 2004

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Article

Evaluation of the ABCR and glutathione peroxidase-3 genes in familial and sporadic cases of exudative age-related macular degeneration.

Barkur S Shastry
Pages: 753-760
Published online on: 01 October 2004

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Article

Characterization of human TMEM16G gene in silico.

Masuko Katoh, Masaru Katoh
Pages: 759-823
Published online on: 01 October 2004

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Article

Measurement of antibody-membrane interactions by surface plasmon resonance.

Alexander Klimka, Mehmet K Tur, Michael Huhn, Uwe Bierfreund, Estela Terrada, Rainer Fischer, Ricarda Finnern, Stefan Barth
Pages: 765-773
Published online on: 01 October 2004

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Article

Additive effect of steroids and cholesterol on the liposomal transfection of the breast cancer cell line T-47D.

Frank Köster, Dominique Finas, Christiane Schulz, Charlotte Hauser, Klaus Diedrich, Ricardo Felberbaum
Pages: 769-841
Published online on: 01 October 2004

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Journal Cover
September-2026 Volume 58 Issue 3

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Mechanisms and therapeutic strategies of pyroptosis in sepsis‑induced acute lung injury (Review)

Wenyu Wu, Nuoran Li, Guoshu Deng, Suyi Yang, Ruifeng Zeng, Rui Chen, Jun Li
Article Number: 264
Published online on: 22 July 2026

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Review Open Access

Gut‑bone metabolites: SCFAs, polyamines and microbial metabolomics in osteoporosis risk and therapy (Review)

Fuchao Chen, Jingyue Sun, Xiao Wang
Article Number: 263
Published online on: 21 July 2026

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Expression of Concern Open Access

[Expression of Concern] Exposure to acoustic stimuli promotes the development and differentiation of neural stem cells from the cochlear nuclei through the clusterin pathway

Tao Xue, Li Wei, Ding-Jun Zha, Li Qiao, Lian-Jun Lu, Fu-Quan Chen, Jian-Hua Qiu
Article Number: 262
Published online on: 20 July 2026

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Article Open Access

Cepharanthine inhibits tick‑borne encephalitis virus infection through modulation of the stress and inflammation response

Wan-Da Tang, Lan-Juan Zhao
Article Number: 261
Published online on: 16 July 2026

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Article Open Access

circCACNA1D drives pulmonary fibrosis by regulating pyruvate kinase M2 dimer‑tetramer switching

Yujie Wang, Xiaoting Li, Meirong Wang, Nailiang Zhai, Mengqi Jiang, Bo Liu, Changjun Lv, Songzi Zhang, Xiaodong Song, Jinjin Zhang
Article Number: 260
Published online on: 15 July 2026

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Review Open Access

Recent progress and therapeutic strategies in the treatment of cervical neuroendocrine neoplasms (Review)

Yanpeng Tian, Yu Zhang, Liling Wang, Zhongkang Li, Xiaotong Xu, Shouze Liu, Shenyu Yang, Xiangyang Ren, Menghan Xu, Xingzi Chang, Xianghua Huang, Qian Zhao, Ruixia Guo
Article Number: 259
Published online on: 15 July 2026

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Review Open Access

Neurofibromin in bone disease: Mechanisms and therapeutic implications (Review)

Shuhong Zhang, Ge Yang
Article Number: 258
Published online on: 14 July 2026

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Review Open Access

Exercise‑induced exosomal noncoding RNAs: Molecular signaling cascades in bone remodeling and translational applications in sports‑related bone injuries (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 257
Published online on: 14 July 2026

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Review Open Access

Targeting alveolar type II cell dysfunction in idiopathic pulmonary fibrosis: Molecular mechanisms and emerging therapeutic strategies (Review)

Tianhao Xie, Kang Hu, Shu Pan, Xin Tong, Haitong Huang, Hao Ding, Jun Zhao
Article Number: 256
Published online on: 13 July 2026

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Article Open Access

Tubular PFKFB3 drives diabetic kidney fibrosis via lactate‑dependent H4K12 lactylation and HIPK2 transactivation

Mingkun Xu, Linhang Fu, Yulong Zhang, Xiuli Guo, Han Wu, Sijing Gao, Fei Xiao, Li Xu
Article Number: 255
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] p73 participates in WWOX-mediated apoptosis in leukemia cells

Donghong Lin, Zhaolei Cui, Lingying Kong, Feng Cheng, Jianping Xu, Fenghua Lan
Article Number: 254
Published online on: 13 July 2026

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Article Open Access

Role of hyperthermia in overcoming HPV‑mediated MHC‑Ⅰ downregulation and promoting immune surveillance

Hanyu Wang, Hongxin Lang, Yaoxing Guo, Te Sun, Yuansong Bai, Tao Zhang, Rui-Qun Qi
Article Number: 253
Published online on: 10 July 2026

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Review Open Access

Endocrine‑metabolic imbalance drives osteoarthritis: From whole‑joint pathobiology to precision therapy (Review)

Ruhui Yang, Haimin Zeng, Qi Xiao, Yining Xie, Yi Long, Xiang Chen
Article Number: 252
Published online on: 09 July 2026

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Expression of Concern Open Access

[Expression of Concern] Roles and mechanisms of action of HNF‑4α in the hepatic differentiation of WB‑F344 cells

Yumeng Shi, Dehua Zhou, Bingyi Wang, Deren Zhou, Baomin Shi
Article Number: 251
Published online on: 08 July 2026

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Phenylalanine exacerbates psoriasiform inflammation through NF‑κB‑mediated dendritic cell activation and Th17 polarization

Yaohan Xu, Jing Pan, Jie Chen, Yutao Zhu, Miaolian Cai, Zeyu Ma, Siji Chen, Tianze Yu, Yushu Wei, Jingying Pan, Kunliang Luo, Yinjing Song, Stijn Van Der Veen, Hao Cheng
Article Number: 250
Published online on: 08 July 2026

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Protective effects of Astragaloside IV on various liver diseases: From chemistry to herbal medicines (Review)

Jialu Shi, Xiaoyu Zhou, Jiabin Wu, Liru Zeng, Xia Wang, Wei Li, Xiao Huang, Xiaoyu Deng, Wenhong Wang
Article Number: 249
Published online on: 07 July 2026

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GRP78 dysregulation: A proposed molecular mechanism linking the tumor microenvironment to sepsis susceptibility in patients with cancer (Review)

Hang Ruan, Meipeng Zhu, Shi-Yan Liu, Li-Juan Zou, Shu-Sheng Li
Article Number: 248
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FGFR1 signaling in rheumatoid arthritis: Mechanisms of bone destruction and therapeutic targeting (Review)

Changzhong Qian, Zhenyu Zhang, Xian Wu, Huibo Ti, Junjie Wu, Zhengdong Yuan, Xia Li, Feng-Lai Yuan
Article Number: 247
Published online on: 06 July 2026

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Retraction Open Access

[Retracted] β‑catenin signaling induces the osteoblastogenic differentiation of human pre‑osteoblastic and bone marrow stromal cells mainly through the upregulation of osterix expression

Bo Liu, Song Wu, Lihua Han, Chaoyue Zhang
Article Number: 246
Published online on: 06 July 2026

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Article Open Access

Single‑cell atlas reveals a Wilms' tumor 1‑mediated axis driving granulosa cell senescence in human ovarian aging

Yanfang Du, Congyu Zhou, Yanpeng Tian, Zhongkang Li, Xianghua Huang
Article Number: 245
Published online on: 03 July 2026

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Review Open Access

TRPV1‑mediated central sensitisation: Core mechanisms of migraine chronification and novel targeted therapeutic strategies (Review)

Mingxia Zhang, Yuting Pu, Yujie Zhang, Jia Hu, Shuangyang Li, Hongmei Tang, Bangjiang Fang, Xue Bai
Article Number: 244
Published online on: 02 July 2026

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Correction Open Access

[Corrigendum] Arginine ADP‑ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway

Lian Yang, Ming Xiao, Xian Li, Yi Tang, Ya-Lan Wang
Article Number: 243
Published online on: 02 July 2026

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Review Open Access

Research progress on the chemical and pharmacological effects of Semen Strychni (Review)

Jingxin Mao, Xin Du, Dan Zeng, Xin Luo, Yan Li
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

FLI1 enhances the malignant phenotype of glioma cells and exerts immunomodulatory effects through feedback crosstalk with exonic circRNA FECR1 and interferon‑induced ISG15

Xue Wen, Xiaoyi Gu, Xu Yan, Naifei Chen, Lei Zhou, Hui Li, Andrew R. Hoffman, Wei Li, Ji-Fan Hu, Jiuwei Cui
Article Number: 241
Published online on: 01 July 2026

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Review Open Access

Role of ZEB1 in angiogenesis and therapeutic potential (Review)

Ruoxin Ren, Chunxiao Yan, Yao Xiang, Lin Jin, Fang Cheng, Lijun Zhang
Article Number: 240
Published online on: 01 July 2026

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Review Open Access

Endothelial dysfunction: A central mechanism linking autosomal dominant polycystic kidney disease and intracranial aneurysms (Review)

Xiaohong Xu, Ruyi Xu, Liexiang Zhang
Article Number: 239
Published online on: 01 July 2026

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Correction Open Access

[Corrigendum] Effect of SDF‑1/CXCR4 axis on the migration of transplanted bone mesenchymal stem cells mobilized by erythropoietin toward lesion sites following spinal cord injury

Jun Li, Weichun Guo, Min Xiong, Heng Han, Jie Chen, Dan Mao, Bing Tang, Hualong Yu, Yun Zeng
Article Number: 238
Published online on: 01 July 2026

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Review Open Access

Exercise and fluoxetine in Alzheimer's disease: Molecular mechanisms of synergistic and antagonistic effects (Review)

Mei Wu, Yan Li
Article Number: 237
Published online on: 30 June 2026

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Review Open Access

Oral‑gut axis in systemic disease: A barrier‑metabolism‑immunity three‑dimensional regulatory model (Review)

Qing Li, Mingrong Cheng, Weiwei Li, Xiaoyue Wang, Xiaoqing Liu, Yujie Yan
Article Number: 236
Published online on: 30 June 2026

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Review Open Access

ABCG2 transporter: Structural and functional associations with gout (Review)

Muhammad Arslan Asif, Zeshan Zulfiqar, Bahar E. Mustafa, Usman Nazir, Jiamen Sun, Zhichang Wang, Yalei Cui, Sun Hao, Liu Boshuai, Yinghua Shi
Article Number: 235
Published online on: 30 June 2026

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Review Open Access

Neuropilin‑1: Emerging roles in nerve‑vessel‑bone coupling during fracture repair (Review)

Keyue Zhang, Tong Li, Huan Liu, Huibo Ti, Zhenyu Zhang, Zhengdong Yuan, Junjie Wu, Xielin Yan, Zixin Luo, Haiting Hu, Xingchen Yao, Shuwen Shi, Xian Wu, Feng-Lai Yuan, Xiao Chen
Article Number: 234
Published online on: 30 June 2026

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Correction Open Access

[Corrigendum] Crocin exerts anti‑inflammatory and anti‑catabolic effects on rat intervertebral discs by suppressing the activation of JNK

Kang Li, Yan Li, Zhenjiang Ma, Jie Zhao
Article Number: 233
Published online on: 29 June 2026

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Review Open Access

Skeletal muscle‑derived extracellular vesicles in multi‑organ degenerative disease: Mechanisms and therapeutic delivery perspectives (Review)

Xianji Wei, Chengyan Guo, Wei Zhang, Guanyi Wang, Wenjing Li, Binghong Gao, Bo Gao, Lingli Zhang
Article Number: 232
Published online on: 26 June 2026

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October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

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Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

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Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

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Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

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Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

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Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Review Open Access

Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Review Open Access

Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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