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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2022 Volume 49 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Doxorubicin sensitizes breast cancer cells to natural killer cells in connection with increased Fas receptors

Nunghathai Sawasdee, Methichit Wattanapanitch, Nontaphat Thongsin, Nattaporn Phanthaphol, Chutipa Chiawpanit, Chanitra Thuwajit, Pa-Thai Yenchitsomanus, Aussara Panya
Article Number: 40
Published online on: 01 February 2022

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Article Open Access

Splice variants denote differences between a cancer stem cell side population of EWSR1‑ERG‑based Ewing sarcoma cells, its main population and EWSR1‑FLI‑based cells

Eberhard Korsching, Julian Matschke, Marc Hotfilder
Article Number: 39
Published online on: 28 January 2022

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Correction Open Access

[Corrigendum] Low‑intensity pulsed ultrasound promotes periodontal ligament stem cell migration through TWIST1‑mediated SDF‑1 expression

Yunji Wang, Jie Li, Ye Qiu, Bo Hu, Jin Chen, Tiwei Fu, Pengfei Zhou, Jinlin Song
Article Number: 38
Published online on: 27 January 2022

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Review Open Access

Current and prospective applications of exosomal microRNAs in pulmonary fibrosis (Review)

Tao Yang, Jian Wang, Jiaying Zhao, Yang Liu
Article Number: 37
Published online on: 24 January 2022

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Correction Open Access

[Corrigendum] SCF increases cardiac stem cell migration through PI3K/AKT and MMP‑2/‑9 signaling

Junli Guo, Wei Jie, Zhihua Shen, Mengsen Li, Youling Lan, Yueqiong Kong, Shaoli Guo, Tianfa Li, Shaojiang Zheng
Article Number: 36
Published online on: 24 January 2022

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Article Open Access

Thrombocytopenia in COVID‑19 and vaccine‑induced thrombotic thrombocytopenia

Styliani A. Geronikolou, Işil Takan, Athanasia Pavlopoulou, Marina Mantzourani, George P. Chrousos
Article Number: 35
Published online on: 21 January 2022

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Article Open Access

XBP1s promotes the development of lung adenocarcinoma via the p‑JNK MAPK pathway

Hongxia Jiang, Qianqian Jiang, Yuanzhou He, Xiaochen Li, Yongjian Xu, Xiansheng Liu
Article Number: 34
Published online on: 20 January 2022

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Hypothesis and Theory

Possible effects of sirolimus treatment on the long‑term efficacy of COVID‑19 vaccination in patients with β‑thalassemia: A theoretical perspective

Matteo Zurlo, Francesco Nicoli, Monica Borgatti, Alessia Finotti, Roberto Gambari
Article Number: 33
Published online on: 19 January 2022

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Article Open Access

Identification of inflammatory response and alternative splicing in acute kidney injury and experimental verification of the involvement of RNA‑binding protein RBFOX1 in this disease

Fangyou Lin, Lei Xu, Run Yuan, Shangting Han, Jinna Xie, Kun Jiang, Bojun Li, Weimin Yu, Ting Rao, Xiangjun Zhou, Fan Cheng
Article Number: 32
Published online on: 19 January 2022

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Article Open Access

2‑Cl‑IB‑MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines

Jana Kotulova, Katerina Lonova, Agata Kubickova, Jana Vrbkova, Pavla Kourilova, Marian Hajduch, Petr Dzubak
Article Number: 31
Published online on: 18 January 2022

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Correction Open Access

[Corrigendum] Panax notoginseng saponins prevent senescence and inhibit apoptosis by regulating the PI3K‑AKT‑mTOR pathway in osteoarthritic chondrocytes

Yubiao Zhang, Weisong Cai, Guangtao Han, Siqi Zhou, Jianping Li, Mao Chen, Haohuan Li
Article Number: 30
Published online on: 17 January 2022

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Article

Efficacy of the use of mefenamic acid combined with standard medical care vs. standard medical care alone for the treatment of COVID‑19: A randomized double‑blind placebo‑controlled trial

Jose Guzman‑Esquivel, Hector R. Galvan‑Salazar, Hannah P. Guzman‑Solorzano, Andrea C. Cuevas‑Velazquez, Jose A. Guzman‑Solorzano, Karen A. Mokay‑Ramirez, Brenda A. Paz‑Michel, Efren Murillo‑Zamora, Josuel Delgado‑Enciso, Valery Melnikov, Osiris G. Delgado‑Enciso, Iram P. Rodriguez‑Sanchez, Margarita L. Martinez‑Fierro, Fabian Rojas‑Larios, Mireya Walle‑Guillen, Citlaly B. Cardenas‑Aguilar, Oscar Beas‑Guzman, Daniel Chaviano‑Conesa, Hossana S. Garcia‑Garcia, Ivan Delgado‑Enciso
Article Number: 29
Published online on: 14 January 2022

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Correction Open Access

[Corrigendum] COX‑2 regulates E‑cadherin expression through the NF‑κB/Snail signaling pathway in gastric cancer

Zhaofeng Chen, Min Liu, Xiaojun Liu, Shanshan Huang, Linlin Li, Bo Song, Hailong Li, Qian Ren, Zenan Hu, Yongning Zhou, Liang Qiao
Article Number: 28
Published online on: 11 January 2022

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Correction Open Access

[Corrigendum] MicroRNA‑1929‑3p participates in murine cytomegalovirus‑induced hypertensive vascular remodeling through Ednra/NLRP3 inflammasome activation

Wei Zhou, Dongmei Xi, Yunzhong Shi, Lamei Wang, Hua Zhong, Zhen Huang, Yongmin Liu, Yan Tang, Ning Lu, Yongjia Wang, Zhengyu Zhang, Jiaxin Pei, Na Tang, Fang He
Article Number: 27
Published online on: 10 January 2022

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Article Open Access

Overexpression of miR‑375 reverses the effects of dexamethasone on the viability, migration, invasion and apoptosis of human airway epithelial cells by targeting DUSP6

Xiaojing Zheng, Chunlian Li, Xiang Gao
Article Number: 26
Published online on: 05 January 2022

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Retraction Open Access

[Retracted] Circular RNA CSNK1G1 promotes the progression of osteoarthritis by targeting the miR‑4428/FUT2 axis

Jianwei Xiao, Rongsheng Wang, Weijian Zhou, Xu Cai, Zhizhong Ye
Article Number: 25
Published online on: 04 January 2022

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Correction Open Access

[Corrigendum] MicroRNA‑24 attenuates diabetic vascular remodeling by suppressing the NLRP3/caspase‑1/IL‑1β signaling pathway

Zhixing Fan, Jian Yang, Chaojun Yang, Jing Zhang, Wanying Cai, Congxin Huang
Article Number: 24
Published online on: 03 January 2022

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis

Enbo Wang, Haixiang Zhang, Dechao Wu, Sadik Ali, Xianglu Ji
Article Number: 105
Published online on: 26 February 2026

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Review Open Access

mTOR signaling pathway in primary Sjögren's syndrome: Pathogenesis and potential therapeutic targets (Review)

Rongxiu Huo, Yanting Yang, Chengcheng Wei, Yang Yang, Danli Meng, Jinying Lin, Xinxiang Huang
Article Number: 104
Published online on: 25 February 2026

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Article Open Access

Bumetanide‑blocked SLC12A2 exerts a protective effect in experimental diabetic retinopathy

Yuting Zhang, Xiuli Wang, Qinyue Xie, Yue Huang, Dongjia Huang, Ziqing Liu, Tong Xu, Man Ni, Hongwei Yang
Article Number: 103
Published online on: 25 February 2026

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Article Open Access

Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 102
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] A novel role for Livin in the response to ultraviolet B radiation and pterygium development

Shuang-Qing Wu, Qi-Bin Xu, Wen-Yan Sheng, Lin-Ya Su, Li-Wei Zhu
Article Number: 101
Published online on: 24 February 2026

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Article Open Access

Endothelial UNC5B regulates blood‑retinal barrier homeostasis

Yujia Yao, Suyu Wang, Jiajun Li, Qianzi Jin, Ziyi Chen, Qin Jiang, Keran Li
Article Number: 100
Published online on: 20 February 2026

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Review Open Access

Metabolic hubs in reproduction: The regulatory network of lipid droplets in gamete and embryo physiology (Review)

Liuzhu Pan, Zongzhuang Wen, Yi Jin
Article Number: 99
Published online on: 17 February 2026

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Review Open Access

The role and mechanism of IL‑35 in myasthenia gravis (Review)

Jing Mao, Lin-Ming Zhang, Yan-Lin Zhu, Shu-Ji Gao, Ming-Wei Liu
Article Number: 98
Published online on: 17 February 2026

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Article Open Access

miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways

Jing Wang, Yujia Zou, Yani Wang, Zheming Yang, Daoshen Liu, Xiaolin Su, Haixu Song, Kai Xu, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 97
Published online on: 16 February 2026

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Review Open Access

Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review)

Yufei Zhong, Yunfei Zou, Zhuoyuan Yang, Junjun Wang, Zezheng Pan, Jiugeng Feng
Article Number: 96
Published online on: 16 February 2026

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Review Open Access

Microglia‑mediated neuroinflammation in intracerebral hemorrhage: Pathological mechanisms and implications for therapeutic development (Review)

Xuehui Fan, Changzhi Pu, Luyi Zhong, Oucheng Wang, Binyi Zhao, Dongyi Liao, Xue Bai, Guiquan Chen, Guoqiang Yang
Article Number: 95
Published online on: 16 February 2026

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Correction Open Access

[Corrigendum] Silencing of Rac1 modifies lung cancer cell migration, invasion and actin cytoskeleton rearrangements and enhances chemosensitivity to antitumor drugs

Qing-Yong Chen, Li-Qun Xu, De-Min Jiao, Qing-Hua Yao, Yan-Yi Wang, Hui-Zhen Hu, Yu-Quan Wu, Jia Song, Jie Yan, Li-Jun Wu
Article Number: 94
Published online on: 12 February 2026

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Article Open Access

Orcinol glucoside ameliorates pulmonary fibrosis by suppressing hyaluronic acid synthesis and macrophage M2 polarization via targeting hyaluronic acid synthase 2

Caizi Li, Xinglinzi Tang, Xiaoru Luo, Xin Lai, Jing Yang, Zheng Xu, Gulizeba Muhetaer, Yizi Xie, Xiufang Huang, Hang Li
Article Number: 93
Published online on: 10 February 2026

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Review Open Access

Helicobacter pylori and hyperglycemia fuel gastric cancer glycolysis: Mechanisms and targeted intervention (Review)

Youjia Liu, Fang Wang, Ya Deng, Yanxia Hu, Feihong Shu, Jie Yu, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Qian Du, Jingyu Xu, Rui Xie
Article Number: 92
Published online on: 09 February 2026

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Review Open Access

Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review)

Jingjing Wu, Siqi Zhang, Junjie Wu, Yuhang Luan, Xingchen Yao, Boyan Xu, Yiting Wang, Yingyue Sheng, Yuzheng Xue, Yilin Ren
Article Number: 91
Published online on: 09 February 2026

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Review Open Access

Chorus line in oral squamous cell carcinoma: How stromal and immune players orchestrate tumor progression (Review)

Eliano Cascardi, Mario Della Mura, Nicoletta Sgarro, Silvia Minei, Gerardo Cazzato, Eugenio Maiorano, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Fábio França Vieira E Silva, Eleonora Lo Muzio, Mario Dioguardi, Andrea Ballini
Article Number: 90
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature 

Xijuan Liu, Chen Yan, Xueqiang Deng, Jingyu Jia
Article Number: 89
Published online on: 09 February 2026

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Review Open Access

Post‑translational modifications in diabetic kidney disease (Review)

Mengfei He, Zihang Wang, Zhuang Miao, Yu Zhao, Lingling Wei, Lijie Zhang, Ruili Yin, Yan Wang, Longyan Yang
Article Number: 88
Published online on: 09 February 2026

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Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Review Open Access

Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Review Open Access

Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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Review Open Access

IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Review Open Access

Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Review Open Access

Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Exosomal circ0000549 promotes MNNG‑induced gastric cancer through miR‑15b‑5p/KIF1B

Zhaofeng Liang, Zihan Gao, Yue Zhang, Jiajia Song, Hui Qian, Xuezhong Xu
Article Number: 114
Published online on: 04 March 2026

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Expression of Concern Open Access

[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy  

Fangfang Li, Ning Zhang, Qingqing Wu, Yuan Yuan, Zheng Yang, Mengqiao Zhou, Jinxiu Zhu, Qizhu Tang
Article Number: 113
Published online on: 04 March 2026

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Review Open Access

Treatment of pulmonary fibrosis: From disease mechanisms to future novel therapies (Review)

Sen Lu, Yunfei Liu, Xiaohua Li, Qipeng Yao
Article Number: 112
Published online on: 03 March 2026

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Review Open Access

Research progress in single‑cell omics technologies for kidney disease (Review)

Jia Xu, Ziwei Chen, Shengyao Li, Xiaoya Wang, Ming Chen
Article Number: 111
Published online on: 03 March 2026

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Review Open Access

CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review)

Xiuping Lai, Yan Yan, Lu Sun, Zili Lei, Yanhong Yang
Article Number: 110
Published online on: 03 March 2026

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Review Open Access

Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)

Sen Lu, Jiale Tong, Jing Jiang, Qin Zhang, Youjin Huang
Article Number: 109
Published online on: 03 March 2026

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Review Open Access

The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)

Yingying Zhang, Ruxin Shen
Article Number: 108
Published online on: 02 March 2026

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Review Open Access

Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

Bojiao Yang, Feng Li, Guimao Cao, Mingtu Nuo, Yaxin Shi, Zilu Wang, Jing Jia, Wei Shi, Zhiyong Liu
Article Number: 107
Published online on: 02 March 2026

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Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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