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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2012 Volume 41 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancers (Review)

Xiaochun Wang, Philip J. Crowe, David Goldstein, Jia-Lin Yang
Pages: 1181-1191
Published online on: 24 July 2012

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Article Open Access

Adenoviral neutral endopeptidase gene delivery in combination with paclitaxel for the treatment of prostate cancer Corrigendum in /10.3892/ijo.2024.5694

Katsuyuki Iida, Rong Zheng, Ruoqian Shen, David M. Nanus
Pages: 1192-1198
Published online on: 08 August 2012

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Article Open Access

Topical phospho-sulindac (OXT-328) is effective in the treatment of non-melanoma skin cancer

Ka Wing Cheng, George Mattheolabakis, Chi C. Wong, Nengtai Ouyang, Liqun Huang, Panayiotis P. Constantinides, Basil Rigas
Pages: 1199-1203
Published online on: 27 July 2012

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Article Open Access

Akt expression and compartmentalization in prediction of clinical outcome in HER2-positive metastatic breast cancer patients treated with trastuzumab

Peter Grell, Pavel Fabian, Marta Khoylou, Lenka Radova, Ondrej Slaby, Roman Hrstka, Rostislav Vyzula, Marian Hajduch, Marek Svoboda
Pages: 1204-1212
Published online on: 27 July 2012

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Article Open Access

First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI)

K. Eichler, S. Zangos, M. G. Mack, R. Hammerstingl, T. Gruber-Rouh, C. Gallus, T. J. Vogl
Pages: 1213-1220
Published online on: 25 July 2012

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Article Open Access

Alterations of MEN1 and E-cadherin/β-catenin complex in sporadic pulmonary carcinoids

Serena Veschi, Rossano Lattanzio, Gitana Maria Aceto, Maria Cristina Curia, Salvatore Magnasco, Domenico Angelucci, Alessandro Cama, Mauro Piantelli, Pasquale Battista
Pages: 1221-1228
Published online on: 20 July 2012

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Article Open Access

Determination of the consequences of VHL mutations on VHL transcripts in renal cell carcinoma

Claire Taylor, Rachel A. Craven, Patricia Harnden, Peter J. Selby, Rosamonde E. Banks
Pages: 1229-1240
Published online on: 20 July 2012

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Article Open Access

A novel method for the in vivo isolation of circulating tumor cells from peripheral blood of cancer patients using a functionalized and structured medical wire

Nadia Saucedo-Zeni, Steffi Mewes, Robert Niestroj, Lukasz Gasiorowski, David Murawa, Piotr Nowaczyk, Tatiana Tomasi, Ekkehard Weber, Grzegorz Dworacki, Nils G. Morgenthaler, Heike Jansen, Corinna Propping, Karolina Sterzynska, Wojciech Dyszkiewicz, Maciej Zabel, Marion Kiechle, Ute Reuning, Manfred Schmitt, Klaus Lücke
Pages: 1241-1250
Published online on: 16 July 2012

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Article Open Access

Radiofrequency currents exert cytotoxic effects in NB69 human neuroblastoma cells but not in peripheral blood mononuclear cells

María Luisa Hernández-Bule, Ernesto Roldán, Joaquín Matilla, María Ángeles Trillo, Alejandro Úbeda
Pages: 1251-1259
Published online on: 24 July 2012

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Article Open Access

Differential expression of HIF-1 in glioblastoma multiforme and anaplastic astrocytoma

Arnulf Mayer, Fabienne Schneider, Peter Vaupel, Clemens Sommer, Heinz Schmidberger
Pages: 1260-1270
Published online on: 16 July 2012

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Article Open Access

Simultaneous siRNA-mediated knockdown of antiapoptotic BCL2, Bcl-xL, XIAP and survivin in bladder cancer cells

Doreen Kunze, Kai Kraemer, Kati Erdmann, Michael Froehner, Manfred  P. Wirth, Susanne Fuessel
Pages: 1271-1277
Published online on: 06 July 2012

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Article

Inhibitory effect of PPARγ on NR0B1 in tumorigenesis of lung adenocarcinoma

Yoshiyuki Susaki, Masayoshi Inoue, Masato Minami, Noriyoshi Sawabata, Yasushi Shintani, Tomoyuki Nakagiri, Soichiro Funaki, Katsuyuki Aozasa, Meinoshin Okumura, Eiichi Morii
Pages: 1278-1284
Published online on: 25 July 2012

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Article

Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis

Minh‑Hue Nguyen, Koji Ueda, Yusuke Nakamura, Yataro Daigo
Pages: 1285-1296
Published online on: 10 August 2012

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Article

Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer

Toru Masuzawa, Yoshiyuki Fujiwara, Kaoru Okada, Ayumu Nakamura, Shuji Takiguchi, Kiyokazu Nakajima, Hiroshi Miyata, Makoto Yamasaki, Yukinori Kurokawa, Ryuji Osawa, Kazuyoshi Takeda, Koji Yoshida, Takuya Tsunoda, Yusuke Nakamura, Masaki Mori, Yuichiro Doki
Pages: 1297-1304
Published online on: 25 July 2012

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Article

Role of metallothionein 1E in the migration and invasion of human glioma cell lines

Hyang-Hwa Ryu, Shin Jung, Tae-Young Jung, Kyung-Sub Moon, In-Young Kim, Young-Il Jeong, Shu-Guang Jin, Jian Pei, Min Wen, Woo-Yeol Jang
Pages: 1305-1313
Published online on: 24 July 2012

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Article

Expression of cancer stem cell markers in pancreatic intraepithelial neoplasias and pancreatic ductal adenocarcinomas

Shoko Kure, Yoko Matsuda, Masahito Hagio, Junji Ueda, Zenya Naito, Toshiyuki Ishiwata
Pages: 1314-1324
Published online on: 23 July 2012

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Article

IDH1/2 mutation is a prognostic marker for survival and predicts response to chemotherapy for grade II gliomas concomitantly treated with radiation therapy

Yoshiko Okita, Yoshitaka Narita, Yasuji Miyakita, Makoto Ohno, Yuko Matsushita, Shintaro Fukushima, Minako Sumi, Koichi Ichimura, Takamasa Kayama, Soichiro Shibui
Pages: 1325-1336
Published online on: 20 July 2012

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Article

The BHLH transcription factor DEC1 plays an important role in the epithelial-mesenchymal transition of pancreatic cancer

Yunyan Wu, Fuyuki Sato, Toshiyuki Yamada, Ujjal Kumar Bhawal, Takeshi Kawamoto, Katsumi Fujimoto, Mitsuhide Noshiro, Hiroko Seino, Satoko Morohashi, Kenichi Hakamada, Yoshimitsu Abiko, Yukio Kato, Hiroshi Kijima
Pages: 1337-1346
Published online on: 18 July 2012

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Article

Loss of HITS (FAM107B) expression in cancers of multiple organs: tissue microarray analysis

Hideo Nakajima, Keita Koizumi, Takuji Tanaka, Yasuhito Ishigaki, Yoshino Yoshitake, Hideto Yonekura, Tsutomu Sakuma, Toshihiro Fukushima, Hisanori Umehara, Soichiro Ueno, Toshinari Minamoto, Yoshiharu Motoo
Pages: 1347-1357
Published online on: 10 July 2012

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Article

Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules

Jae Ju Jeong, Jae Heun Lee, Ki Churl Chang, Hye Jung Kim
Pages: 1358-1364
Published online on: 07 August 2012

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Article

Novel monoclonal antibodies specific for CTLD-SSC and sialomucin domains of endosialin, a mural cell marker of tumor vasculature

Soňa Kontseková, Anna Ohradanova Repic, Katarína Polčicová, Pauliina Tuomaala, Jaromír Pastorek, Silvia Pastoreková, Seppo Parkkila, Monika Baráthová
Pages: 1365-1372
Published online on: 23 July 2012

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Article

Expression of melanocortin receptors in human prostate cancer cell lines: MC2R activation by ACTH increases prostate cancer cell proliferation

Saly Hafiz, John C. Dennis, Dean Schwartz, Robert Judd, Ya‑Xiong Tao, Kamel Khazal, Benson Akingbemi, Xiu-Lei Mo, Asim B. Abdel‑Mageed, Edward Morrison, Mahmoud Mansour
Pages: 1373-1380
Published online on: 25 July 2012

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Article

The mTOR inhibitor RAD001 augments radiation-induced growth inhibition in a hepatocellular carcinoma cell line by increasing autophagy

Anaïs Altmeyer, Elodie Josset, Jean-Marc Denis, John  Gueulette, Jakobus  Slabbert, Didier Mutter, Georges Noël, Pierre  Bischoff
Pages: 1381-1386
Published online on: 07 August 2012

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Article

A smoking-associated 7-gene signature for lung cancer diagnosis and prognosis

Ying-Wooi Wan, Rebecca A. Raese, James E. Fortney, Changchang Xiao, Dajie Luo, John Cavendish, Laura F. Gibson, Vincent Castranova, Yong Qian, Nancy Lan Guo
Pages: 1387-1396
Published online on: 16 July 2012

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Article

Genomic CGH-assessed structural DNA alterations in rectal carcinoma as related to local recurrence following primary operation for cure

K. Kodeda, A. Gustafsson Asting, C. Lönnroth, K. Derwinger, Y. Wettergren, S. Nordgren, B. Gustavsson, K. Lundholm
Pages: 1397-1404
Published online on: 20 July 2012

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Article

A single nucleotide polymorphism in the human PIGK gene associates with low PIGK expression in colorectal cancer patients

Santanu Dasgupta, Prodipto Pal, Nitai D. Mukhopadhyay, Yumei Fu, Edward A. Ratovitski, Chul-So Moon, Mohammad Obaidul Hoque, Paul B. Fisher, Barry Trink
Pages: 1405-1410
Published online on: 23 July 2012

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Article

The Hedgehog signaling pathway in ovarian teratoma is stimulated by Sonic Hedgehog which induces internalization of Patched

Maja Sabol, Diana Car, Vesna Musani, Petar Ozretic, Slavko Oreskovic, Igor Weber, Sonja Levanat
Pages: 1411-1418
Published online on: 13 July 2012

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Article

Cytokine-like 1 is involved in the growth and metastasis of neuroblastoma cells

Mingjie Wen, Huanmin Wang, Xulong Zhang, Jun Long, Zhe Lv, Qingli Kong, Yunqing An
Pages: 1419-1424
Published online on: 13 July 2012

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Article

Antimycin A sensitizes cells to TRAIL-induced apoptosis through upregulation of DR5 and downregulation of c-FLIP and Bcl-2

Sung-Jun Lee, Eun-Ae Kim, Kyoung Seob Song, Min-Jae Kim, Dae Hyung Lee, Taeg Kyu Kwon, Tae-Jin Lee
Pages: 1425-1430
Published online on: 27 July 2012

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Article

Bufalin increases sensitivity to AKT/mTOR-induced autophagic cell death in SK-HEP-1 human hepatocellular carcinoma cells

Shih-Chang Tsai, Jai-Sing Yang, Shu-Fen Peng, Chi-Cheng Lu, Jo-Hua Chiang, Jing-Gung Chung, Meng-Wei Lin, Jen-Kun Lin, Sakae Amagaya, Cinderella Wai-Shan Chung, Theng-Thang Tung, Wen-Wen Huang, Michael T. Tseng
Pages: 1431-1442
Published online on: 31 July 2012

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Article

Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells

Seung Hee Yoo, Young Geol Yoon, Jee Suk Lee, Yeon Suk Song, Joon Seok Oh, Bong Soo Park, Taeg Kyu Kwon, Cheol Park, Yung Hyun Choi, Young Hyun Yoo
Pages: 1443-1454
Published online on: 07 August 2012

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Article

Analysis of a novel highly metastatic melanoma cell line identifies osteopontin as a new lymphangiogenic factor

Ruediger Liersch, Jay W. Shin, Michael Bayer, Christian Schwöppe, Christoph Schliemann, Wolfgang E. Berdel, Rolf Mesters, Michael Detmar
Pages: 1455-1463
Published online on: 06 July 2012

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Article

Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells

Haley L. Peters, Amit Tuli, Xiaojian Wang, Cuiling Liu, Zenggang Pan, Michel M. Ouellette, Michael A. Hollingsworth, Richard G. MacDonald, Joyce C. Solheim
Pages: 1464-1474
Published online on: 13 July 2012

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Article

Inhibition of Aurora-B kinase activity confers antitumor efficacy in preclinical mouse models of early and advanced gastrointestinal neoplasia

Denis G. Alferez, Robert A. Goodlad, Rajesh Odedra, Patrizia  Sini, Claire  Crafter, Anderson J. Ryan, Stephen R. Wedge, Nicholas   A. Wright, Elizabeth Anderson, Robert W. Wilkinson
Pages: 1475-1485
Published online on: 31 July 2012

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Article

SAHA/Vorinostat induces the expression of the CD137 receptor/ligand system and enhances apoptosis mediated by soluble CD137 receptor in a human breast cancer cell line

Daniela Bellarosa, Alessandro Bressan, Mario Bigioni, Massimo Parlani, Carlo Alberto Maggi, Monica Binaschi
Pages: 1486-1494
Published online on: 13 July 2012

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Article

Arachidonic acid metabolism in human prostate cancer

Peiying Yang, Carrie A. Cartwright, Jin Li, Sijin Wen, Ina N. Prokhorova, Imad  Shureiqi, Patricia Troncoso, Nora M. Navone, Robert A. Newman, Jeri Kim
Pages: 1495-1503
Published online on: 10 August 2012

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Article

The enhanced antitumor effects of biodegradable cationic heparin-polyethyleneimine nanogels delivering HSulf-1 gene combined with cisplatin on ovarian cancer

Ping Liu, Maling Gou, Tao Yi, Xiaorong Qi, Chuan Xie, Shengtao Zhou, Hongxin Deng, Yuquan Wei, Xia Zhao
Pages: 1504-1512
Published online on: 18 July 2012

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Article

Antitumor effects of the novel quinazolinone MJ-33: Inhibition of metastasis through the MAPK, AKT, NF-κB and AP-1 signaling pathways in DU145 human prostate cancer cells

Mann-Jen Hour, Shih-Chang Tsai, Hsi-Chin Wu, Meng-Wei Lin, Jing‑Gung  Chung, Jin-Bin Wu, Jo-Hua Chiang, Minoru Tsuzuki, Jai-Sing Yang
Pages: 1513-1519
Published online on: 18 July 2012

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Article

Silencing of SNX1 by siRNA stimulates the ligand-induced endocytosis of EGFR and increases EGFR phosphorylation in gefitinib-resistant human lung cancer cell lines

Yukio Nishimura, Soichi Takiguchi, Kiyoko Yoshioka, Yusaku Nakabeppu, Kazuyuki Itoh
Pages: 1520-1530
Published online on: 31 July 2012

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Article

The NEDD8 conjugation pathway regulates p53 transcriptional activity and head and neck cancer cell sensitivity to ionizing radiation

Sébastien Guihard, Ludivine Ramolu, Christine Macabre, Bohdan  Wasylyk, Georges Noël, Joseph Abecassis, Alain C. Jung
Pages: 1531-1540
Published online on: 07 August 2012

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Article

Biological influence of brain-derived neurotrophic factor on breast cancer cells

Xiaomei Yang, Tracey A. Martin, Wen G. Jiang
Pages: 1541-1546
Published online on: 06 August 2012

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Article

Parthenolide suppresses tumor growth in a xenograft model of colorectal cancer cells by inducing mitochondrial dysfunction and apoptosis

Se-Lim Kim, Kieu The Thu Trang, Seong Hun Kim, In Hee Kim, Seung Ok Lee, Soo Teik Lee, Dae Ghon Kim, Sang-Wook Kim
Pages: 1547-1553
Published online on: 09 August 2012

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Targeted therapies for urothelial carcinoma: From FGFR inhibitors to next‑generation antibody-drug conjugates (Review)

Jinping Du, Hao Shen, Tongwei Zeng, Wei Liu, Yongqiang Xie
Article Number: 28
Published online on: 22 December 2025

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Expression of Concern Open Access

[Expression of Concern] Establishment and evaluation of a new highly metastatic tumor cell line 5a‑D‑Luc‑ZsGreen expressing both luciferase and green fluorescent protein

Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Hiroyuki Takuwa, Kazuto Masamoto, Yutaka Tomita, Norihiro Suzuki, Takeshi Imamura, Mitsuru Koizumi, Tsuneo Saga
Article Number: 27
Published online on: 17 December 2025

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Review Open Access

Exosomal circRNAs in hepatocellular carcinoma: Implications for the development and therapeutic resistance of hepatocellular carcinoma (Review)

Zhiyao Liu, Yuqiao Wang, Yali Wang, Yucheng Zhang
Article Number: 26
Published online on: 16 December 2025

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Review Open Access

Advancements on the synergistic application of oncolytic viruses and molecularly targeted therapies for the treatment of solid tumors (Review)

Shiwen Bi, Tiyan Shan, Yong Tang, Qi Wang
Article Number: 25
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] Epigenetic high regulation of ATAD2 regulates the Hh pathway in human hepatocellular carcinoma

Gang Wu, Xiaojun Lu, Yawei Wang, Hui He, Xiangyu Meng, Shuguan Xia, Kunming Zhen, Yongfeng Liu
Article Number: 24
Published online on: 16 December 2025

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Review

CCDC137: A key hub for RNA and epigenetic regulation in cancer research (Review)

Xiaoying Zhao, Wenjing Zhang, Xiang Yu, Xiaohan Zhao, Xu Dai, Sirui Chen, Yan Wang, Jiang Cheng, Weiwei Zheng
Article Number: 23
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] Characterization of side population cells isolated from the colon cancer cell line SW480

Binghong Xiong, Li Ma, Xiang Hu, Caiquan Zhang, Yong Cheng
Article Number: 22
Published online on: 10 December 2025

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Review Open Access

mTOR in radiotherapy of lung cancer: Mechanisms of radiation resistance and therapeutic implications (Review)

Xiao Pang, Huai Liu, Ying Long, Hui Wang
Article Number: 21
Published online on: 08 December 2025

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Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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Journal Cover
March-2026 Volume 68 Issue 3

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Suppression of the death gene BIK is a critical factor for resistance to tamoxifen in MCF‑7 breast cancer cells

Rubí Viedma-Rodriguez, Luis Arturo Baiza-Gutman, Alejandro García-Carrancá, Leticia Moreno-Fierros, Fabio Salamanca-Gómez, Diego Arenas-Aranda
Article Number: 29
Published online on: 23 December 2025

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