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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2012 Volume 41 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancers (Review)

Xiaochun Wang, Philip J. Crowe, David Goldstein, Jia-Lin Yang
Pages: 1181-1191
Published online on: 24 July 2012

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Article Open Access

Adenoviral neutral endopeptidase gene delivery in combination with paclitaxel for the treatment of prostate cancer Corrigendum in /10.3892/ijo.2024.5694

Katsuyuki Iida, Rong Zheng, Ruoqian Shen, David M. Nanus
Pages: 1192-1198
Published online on: 08 August 2012

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Article Open Access

Topical phospho-sulindac (OXT-328) is effective in the treatment of non-melanoma skin cancer

Ka Wing Cheng, George Mattheolabakis, Chi C. Wong, Nengtai Ouyang, Liqun Huang, Panayiotis P. Constantinides, Basil Rigas
Pages: 1199-1203
Published online on: 27 July 2012

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Article Open Access

Akt expression and compartmentalization in prediction of clinical outcome in HER2-positive metastatic breast cancer patients treated with trastuzumab

Peter Grell, Pavel Fabian, Marta Khoylou, Lenka Radova, Ondrej Slaby, Roman Hrstka, Rostislav Vyzula, Marian Hajduch, Marek Svoboda
Pages: 1204-1212
Published online on: 27 July 2012

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Article Open Access

First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI)

K. Eichler, S. Zangos, M. G. Mack, R. Hammerstingl, T. Gruber-Rouh, C. Gallus, T. J. Vogl
Pages: 1213-1220
Published online on: 25 July 2012

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Article Open Access

Alterations of MEN1 and E-cadherin/β-catenin complex in sporadic pulmonary carcinoids

Serena Veschi, Rossano Lattanzio, Gitana Maria Aceto, Maria Cristina Curia, Salvatore Magnasco, Domenico Angelucci, Alessandro Cama, Mauro Piantelli, Pasquale Battista
Pages: 1221-1228
Published online on: 20 July 2012

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Article Open Access

Determination of the consequences of VHL mutations on VHL transcripts in renal cell carcinoma

Claire Taylor, Rachel A. Craven, Patricia Harnden, Peter J. Selby, Rosamonde E. Banks
Pages: 1229-1240
Published online on: 20 July 2012

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Article Open Access

A novel method for the in vivo isolation of circulating tumor cells from peripheral blood of cancer patients using a functionalized and structured medical wire

Nadia Saucedo-Zeni, Steffi Mewes, Robert Niestroj, Lukasz Gasiorowski, David Murawa, Piotr Nowaczyk, Tatiana Tomasi, Ekkehard Weber, Grzegorz Dworacki, Nils G. Morgenthaler, Heike Jansen, Corinna Propping, Karolina Sterzynska, Wojciech Dyszkiewicz, Maciej Zabel, Marion Kiechle, Ute Reuning, Manfred Schmitt, Klaus Lücke
Pages: 1241-1250
Published online on: 16 July 2012

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Article Open Access

Radiofrequency currents exert cytotoxic effects in NB69 human neuroblastoma cells but not in peripheral blood mononuclear cells

María Luisa Hernández-Bule, Ernesto Roldán, Joaquín Matilla, María Ángeles Trillo, Alejandro Úbeda
Pages: 1251-1259
Published online on: 24 July 2012

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Article Open Access

Differential expression of HIF-1 in glioblastoma multiforme and anaplastic astrocytoma

Arnulf Mayer, Fabienne Schneider, Peter Vaupel, Clemens Sommer, Heinz Schmidberger
Pages: 1260-1270
Published online on: 16 July 2012

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Article Open Access

Simultaneous siRNA-mediated knockdown of antiapoptotic BCL2, Bcl-xL, XIAP and survivin in bladder cancer cells

Doreen Kunze, Kai Kraemer, Kati Erdmann, Michael Froehner, Manfred  P. Wirth, Susanne Fuessel
Pages: 1271-1277
Published online on: 06 July 2012

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Article

Inhibitory effect of PPARγ on NR0B1 in tumorigenesis of lung adenocarcinoma

Yoshiyuki Susaki, Masayoshi Inoue, Masato Minami, Noriyoshi Sawabata, Yasushi Shintani, Tomoyuki Nakagiri, Soichiro Funaki, Katsuyuki Aozasa, Meinoshin Okumura, Eiichi Morii
Pages: 1278-1284
Published online on: 25 July 2012

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Article

Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis

Minh‑Hue Nguyen, Koji Ueda, Yusuke Nakamura, Yataro Daigo
Pages: 1285-1296
Published online on: 10 August 2012

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Article

Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer

Toru Masuzawa, Yoshiyuki Fujiwara, Kaoru Okada, Ayumu Nakamura, Shuji Takiguchi, Kiyokazu Nakajima, Hiroshi Miyata, Makoto Yamasaki, Yukinori Kurokawa, Ryuji Osawa, Kazuyoshi Takeda, Koji Yoshida, Takuya Tsunoda, Yusuke Nakamura, Masaki Mori, Yuichiro Doki
Pages: 1297-1304
Published online on: 25 July 2012

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Article

Role of metallothionein 1E in the migration and invasion of human glioma cell lines

Hyang-Hwa Ryu, Shin Jung, Tae-Young Jung, Kyung-Sub Moon, In-Young Kim, Young-Il Jeong, Shu-Guang Jin, Jian Pei, Min Wen, Woo-Yeol Jang
Pages: 1305-1313
Published online on: 24 July 2012

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Article

Expression of cancer stem cell markers in pancreatic intraepithelial neoplasias and pancreatic ductal adenocarcinomas

Shoko Kure, Yoko Matsuda, Masahito Hagio, Junji Ueda, Zenya Naito, Toshiyuki Ishiwata
Pages: 1314-1324
Published online on: 23 July 2012

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Article

IDH1/2 mutation is a prognostic marker for survival and predicts response to chemotherapy for grade II gliomas concomitantly treated with radiation therapy

Yoshiko Okita, Yoshitaka Narita, Yasuji Miyakita, Makoto Ohno, Yuko Matsushita, Shintaro Fukushima, Minako Sumi, Koichi Ichimura, Takamasa Kayama, Soichiro Shibui
Pages: 1325-1336
Published online on: 20 July 2012

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Article

The BHLH transcription factor DEC1 plays an important role in the epithelial-mesenchymal transition of pancreatic cancer

Yunyan Wu, Fuyuki Sato, Toshiyuki Yamada, Ujjal Kumar Bhawal, Takeshi Kawamoto, Katsumi Fujimoto, Mitsuhide Noshiro, Hiroko Seino, Satoko Morohashi, Kenichi Hakamada, Yoshimitsu Abiko, Yukio Kato, Hiroshi Kijima
Pages: 1337-1346
Published online on: 18 July 2012

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Article

Loss of HITS (FAM107B) expression in cancers of multiple organs: tissue microarray analysis

Hideo Nakajima, Keita Koizumi, Takuji Tanaka, Yasuhito Ishigaki, Yoshino Yoshitake, Hideto Yonekura, Tsutomu Sakuma, Toshihiro Fukushima, Hisanori Umehara, Soichiro Ueno, Toshinari Minamoto, Yoshiharu Motoo
Pages: 1347-1357
Published online on: 10 July 2012

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Article

Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules

Jae Ju Jeong, Jae Heun Lee, Ki Churl Chang, Hye Jung Kim
Pages: 1358-1364
Published online on: 07 August 2012

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Article

Novel monoclonal antibodies specific for CTLD-SSC and sialomucin domains of endosialin, a mural cell marker of tumor vasculature

Soňa Kontseková, Anna Ohradanova Repic, Katarína Polčicová, Pauliina Tuomaala, Jaromír Pastorek, Silvia Pastoreková, Seppo Parkkila, Monika Baráthová
Pages: 1365-1372
Published online on: 23 July 2012

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Article

Expression of melanocortin receptors in human prostate cancer cell lines: MC2R activation by ACTH increases prostate cancer cell proliferation

Saly Hafiz, John C. Dennis, Dean Schwartz, Robert Judd, Ya‑Xiong Tao, Kamel Khazal, Benson Akingbemi, Xiu-Lei Mo, Asim B. Abdel‑Mageed, Edward Morrison, Mahmoud Mansour
Pages: 1373-1380
Published online on: 25 July 2012

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Article

The mTOR inhibitor RAD001 augments radiation-induced growth inhibition in a hepatocellular carcinoma cell line by increasing autophagy

Anaïs Altmeyer, Elodie Josset, Jean-Marc Denis, John  Gueulette, Jakobus  Slabbert, Didier Mutter, Georges Noël, Pierre  Bischoff
Pages: 1381-1386
Published online on: 07 August 2012

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Article

A smoking-associated 7-gene signature for lung cancer diagnosis and prognosis

Ying-Wooi Wan, Rebecca A. Raese, James E. Fortney, Changchang Xiao, Dajie Luo, John Cavendish, Laura F. Gibson, Vincent Castranova, Yong Qian, Nancy Lan Guo
Pages: 1387-1396
Published online on: 16 July 2012

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Article

Genomic CGH-assessed structural DNA alterations in rectal carcinoma as related to local recurrence following primary operation for cure

K. Kodeda, A. Gustafsson Asting, C. Lönnroth, K. Derwinger, Y. Wettergren, S. Nordgren, B. Gustavsson, K. Lundholm
Pages: 1397-1404
Published online on: 20 July 2012

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Article

A single nucleotide polymorphism in the human PIGK gene associates with low PIGK expression in colorectal cancer patients

Santanu Dasgupta, Prodipto Pal, Nitai D. Mukhopadhyay, Yumei Fu, Edward A. Ratovitski, Chul-So Moon, Mohammad Obaidul Hoque, Paul B. Fisher, Barry Trink
Pages: 1405-1410
Published online on: 23 July 2012

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Article

The Hedgehog signaling pathway in ovarian teratoma is stimulated by Sonic Hedgehog which induces internalization of Patched

Maja Sabol, Diana Car, Vesna Musani, Petar Ozretic, Slavko Oreskovic, Igor Weber, Sonja Levanat
Pages: 1411-1418
Published online on: 13 July 2012

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Article

Cytokine-like 1 is involved in the growth and metastasis of neuroblastoma cells

Mingjie Wen, Huanmin Wang, Xulong Zhang, Jun Long, Zhe Lv, Qingli Kong, Yunqing An
Pages: 1419-1424
Published online on: 13 July 2012

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Article

Antimycin A sensitizes cells to TRAIL-induced apoptosis through upregulation of DR5 and downregulation of c-FLIP and Bcl-2

Sung-Jun Lee, Eun-Ae Kim, Kyoung Seob Song, Min-Jae Kim, Dae Hyung Lee, Taeg Kyu Kwon, Tae-Jin Lee
Pages: 1425-1430
Published online on: 27 July 2012

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Article

Bufalin increases sensitivity to AKT/mTOR-induced autophagic cell death in SK-HEP-1 human hepatocellular carcinoma cells

Shih-Chang Tsai, Jai-Sing Yang, Shu-Fen Peng, Chi-Cheng Lu, Jo-Hua Chiang, Jing-Gung Chung, Meng-Wei Lin, Jen-Kun Lin, Sakae Amagaya, Cinderella Wai-Shan Chung, Theng-Thang Tung, Wen-Wen Huang, Michael T. Tseng
Pages: 1431-1442
Published online on: 31 July 2012

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Article

Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells

Seung Hee Yoo, Young Geol Yoon, Jee Suk Lee, Yeon Suk Song, Joon Seok Oh, Bong Soo Park, Taeg Kyu Kwon, Cheol Park, Yung Hyun Choi, Young Hyun Yoo
Pages: 1443-1454
Published online on: 07 August 2012

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Article

Analysis of a novel highly metastatic melanoma cell line identifies osteopontin as a new lymphangiogenic factor

Ruediger Liersch, Jay W. Shin, Michael Bayer, Christian Schwöppe, Christoph Schliemann, Wolfgang E. Berdel, Rolf Mesters, Michael Detmar
Pages: 1455-1463
Published online on: 06 July 2012

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Article

Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells

Haley L. Peters, Amit Tuli, Xiaojian Wang, Cuiling Liu, Zenggang Pan, Michel M. Ouellette, Michael A. Hollingsworth, Richard G. MacDonald, Joyce C. Solheim
Pages: 1464-1474
Published online on: 13 July 2012

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Article

Inhibition of Aurora-B kinase activity confers antitumor efficacy in preclinical mouse models of early and advanced gastrointestinal neoplasia

Denis G. Alferez, Robert A. Goodlad, Rajesh Odedra, Patrizia  Sini, Claire  Crafter, Anderson J. Ryan, Stephen R. Wedge, Nicholas   A. Wright, Elizabeth Anderson, Robert W. Wilkinson
Pages: 1475-1485
Published online on: 31 July 2012

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Article

SAHA/Vorinostat induces the expression of the CD137 receptor/ligand system and enhances apoptosis mediated by soluble CD137 receptor in a human breast cancer cell line

Daniela Bellarosa, Alessandro Bressan, Mario Bigioni, Massimo Parlani, Carlo Alberto Maggi, Monica Binaschi
Pages: 1486-1494
Published online on: 13 July 2012

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Article

Arachidonic acid metabolism in human prostate cancer

Peiying Yang, Carrie A. Cartwright, Jin Li, Sijin Wen, Ina N. Prokhorova, Imad  Shureiqi, Patricia Troncoso, Nora M. Navone, Robert A. Newman, Jeri Kim
Pages: 1495-1503
Published online on: 10 August 2012

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Article

The enhanced antitumor effects of biodegradable cationic heparin-polyethyleneimine nanogels delivering HSulf-1 gene combined with cisplatin on ovarian cancer

Ping Liu, Maling Gou, Tao Yi, Xiaorong Qi, Chuan Xie, Shengtao Zhou, Hongxin Deng, Yuquan Wei, Xia Zhao
Pages: 1504-1512
Published online on: 18 July 2012

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Article

Antitumor effects of the novel quinazolinone MJ-33: Inhibition of metastasis through the MAPK, AKT, NF-κB and AP-1 signaling pathways in DU145 human prostate cancer cells

Mann-Jen Hour, Shih-Chang Tsai, Hsi-Chin Wu, Meng-Wei Lin, Jing‑Gung  Chung, Jin-Bin Wu, Jo-Hua Chiang, Minoru Tsuzuki, Jai-Sing Yang
Pages: 1513-1519
Published online on: 18 July 2012

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Article

Silencing of SNX1 by siRNA stimulates the ligand-induced endocytosis of EGFR and increases EGFR phosphorylation in gefitinib-resistant human lung cancer cell lines

Yukio Nishimura, Soichi Takiguchi, Kiyoko Yoshioka, Yusaku Nakabeppu, Kazuyuki Itoh
Pages: 1520-1530
Published online on: 31 July 2012

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Article

The NEDD8 conjugation pathway regulates p53 transcriptional activity and head and neck cancer cell sensitivity to ionizing radiation

Sébastien Guihard, Ludivine Ramolu, Christine Macabre, Bohdan  Wasylyk, Georges Noël, Joseph Abecassis, Alain C. Jung
Pages: 1531-1540
Published online on: 07 August 2012

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Article

Biological influence of brain-derived neurotrophic factor on breast cancer cells

Xiaomei Yang, Tracey A. Martin, Wen G. Jiang
Pages: 1541-1546
Published online on: 06 August 2012

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Article

Parthenolide suppresses tumor growth in a xenograft model of colorectal cancer cells by inducing mitochondrial dysfunction and apoptosis

Se-Lim Kim, Kieu The Thu Trang, Seong Hun Kim, In Hee Kim, Seung Ok Lee, Soo Teik Lee, Dae Ghon Kim, Sang-Wook Kim
Pages: 1547-1553
Published online on: 09 August 2012

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Journal Cover
April-2026 Volume 68 Issue 4

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Cover Legend PDF

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

Overcoming acquired doxorubicin resistance of ovarian carcinoma cells by verapamil‑mediated promotion of DNA damage‑driven cytotoxicity

Elvira Mukinovic, Sina Federmann, Larissa Messling, Marlena Sekeres, Julia Mann, Lena Abbey, Matthias U. Kassack, Gerhard Fritz
Article Number: 48
Published online on: 24 February 2026

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Review Open Access

IL‑6: A key player in the EGFR‑TKI‑resistant tumor microenvironment and its therapeutic implications (Review)

Qi Wei, Chengming Huang, Yuanyuan Zhang, Hao Zeng, Chang Qi, Sihan Tan, Weimin Li, Panwen Tian, Yalun Li
Article Number: 47
Published online on: 20 February 2026

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Review

Mechanisms of chemoresistance in diffuse large B‑cell lymphoma and novel therapeutic strategies (Review)

Mengdi Wan, Xi Wang, Bin Luo, Huangming Hong, Yizhun Zhu, Tongyu Lin
Article Number: 46
Published online on: 20 February 2026

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Article Open Access

lncRNA AL445238.2‑USP4 axis regulates cell survival and stemness in colon cancer

Hualong Lin, Jieni Feng, Peirui Chen, Jialin Hu, Linjia Zhu, Shaofei Yuan
Article Number: 45
Published online on: 20 February 2026

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Review Open Access

Beyond the membrane: Internalization and compartmentalization of insulin‑like growth factor 1 receptor signaling in cancer pathogenesis and treatment (Review)

Tiehong Zhang, Ling Li, Chunling Du
Article Number: 44
Published online on: 18 February 2026

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Review Open Access

Role and underlying mechanisms of miR‑200 family in breast cancer (Review)

Jiaqi Liu, Hua Du, Yingxu Shi
Article Number: 43
Published online on: 16 February 2026

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Review Open Access

Role of SPAG6 in regulating physiological functions and tumorigenesis (Review)

Yu Luo, Qibing Yan, Pohao Zhang, Hui Xu, Rong Zhang, Ruihe Wang, Yongkang Wu
Article Number: 42
Published online on: 12 February 2026

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Correction Open Access

[Corrigendum] Podoplanin‑mediated TGF‑β‑induced epithelial‑mesen‑ chymal transition and its correlation with bHLH transcription factor DEC in TE‑11 cells

Yunyan Wu, Qiang Liu, Xu Yan, Yukio Kato, Makiko Tanaka, Sadaki Inokuchi, Tadashi Yoshizawa, Satoko Morohashi, Hiroshi Kijima
Article Number: 41
Published online on: 11 February 2026

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Review Open Access

Emerging roles of RNA m6A modification in multiple myeloma pathogenesis and treatment resistance (Review)

Yasen Maimaitiyiming, Shuoyang Hu, Die Bai, Yingchao Guan, Na Bu, Wenhui Hao, Mayila Maimaiti
Article Number: 40
Published online on: 10 February 2026

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Correction Open Access

[Corrigendum] The p85α regulatory subunit of PI3K mediates cAMP‑PKA and retinoic acid biological effects on MCF7 cell growth and migration

Caterina F. Donini, Erika Di Zazzo, Candida Zuchegna, Marina Di Domenico, Sonia D'Inzeo, Arianna Nicolussi, Enrico V. Avvedimento, Anna Coppa, Antonio Porcellini
Article Number: 39
Published online on: 02 February 2026

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Review Open Access

Advances in the study of the breast carcinoma exosomal microRNAs: From basic mechanisms to clinical applications (Review)

Zhi-Min Chen, Peng Huang, Dun-Yang Yang, Shu Lin, Si-Qing Cai
Article Number: 38
Published online on: 30 January 2026

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Retraction Open Access

[Retracted] Matrix metalloproteinase‑1 promotes prostate tumor growth and metastasis

Sai Murali Krishna Pulukuri, Jasti S. Rao
Article Number: 37
Published online on: 19 January 2026

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May-2026 Volume 68 Issue 5

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Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Correction Open Access

[Corrigendum] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 51
Published online on: 26 February 2026

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Article Open Access

RNA‑binding protein DAZAP1 promotes gastric cancer metastasis by enhancing NOTCH1 and JAG1 mRNA stability

Siyang Peng, Yidong Chen, Jieke Wu, Xiaodong Huang, Linjie Hong, Yanci Xie, Yuting Lei, Xiangyang Wei, Ping Yang, Jieming Zhang, Qiong Yang, Guangnan Liu, Aimin Li, Side Liu, Jiaying Li, Weiyu Dai, Yanfeng Hu, Jing Wang, Jing Xiong, Jide Wang
Article Number: 50
Published online on: 26 February 2026

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Retraction Open Access

[Retracted] Knockdown of MALAT1 inhibits osteosarcoma progression via regulating the miR‑34a/cyclin D1 axis

Guangchao Duan, Chuanlin Zhang, Changke Xu, Chao Xu, Lei Zhang, Yan Zhang
Article Number: 49
Published online on: 24 February 2026

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