Journal Articles

STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancers (Review)

Xiaochun Wang, Philip J. Crowe, David Goldstein, Jia-Lin Yang

Pages: 1181-1191 Published online on: 24 July 2012
Open Access

Adenoviral neutral endopeptidase gene delivery in combination with paclitaxel for the treatment of prostate cancer

Katsuyuki Iida, Rong Zheng, Ruoqian Shen, David M. Nanus

Pages: 1192-1198 Published online on: 08 August 2012
Open Access

Topical phospho-sulindac (OXT-328) is effective in the treatment of non-melanoma skin cancer

Ka Wing Cheng, George Mattheolabakis, Chi C. Wong, Nengtai Ouyang, Liqun Huang, Panayiotis P. Constantinides, Basil Rigas

Pages: 1199-1203 Published online on: 27 July 2012
Open Access

Akt expression and compartmentalization in prediction of clinical outcome in HER2-positive metastatic breast cancer patients treated with trastuzumab

Peter Grell, Pavel Fabian, Marta Khoylou, Lenka Radova, Ondrej Slaby, Roman Hrstka, Rostislav Vyzula, Marian Hajduch, Marek Svoboda

Pages: 1204-1212 Published online on: 27 July 2012
Open Access

First human study in treatment of unresectable liver metastases from colorectal cancer with irinotecan-loaded beads (DEBIRI)

K. Eichler, S. Zangos, M. G. Mack, R. Hammerstingl, T. Gruber-Rouh, C. Gallus, T. J. Vogl

Pages: 1213-1220 Published online on: 25 July 2012
Open Access

Alterations of MEN1 and E-cadherin/β-catenin complex in sporadic pulmonary carcinoids

Serena Veschi, Rossano Lattanzio, Gitana Maria Aceto, Maria Cristina Curia, Salvatore Magnasco, Domenico Angelucci, Alessandro Cama, Mauro Piantelli, Pasquale Battista

Pages: 1221-1228 Published online on: 20 July 2012
Open Access

Determination of the consequences of VHL mutations on VHL transcripts in renal cell carcinoma

Claire Taylor, Rachel A. Craven, Patricia Harnden, Peter J. Selby, Rosamonde E. Banks

Pages: 1229-1240 Published online on: 20 July 2012
Open Access

A novel method for the in vivo isolation of circulating tumor cells from peripheral blood of cancer patients using a functionalized and structured medical wire

Nadia Saucedo-Zeni, Steffi Mewes, Robert Niestroj, Lukasz Gasiorowski, David Murawa, Piotr Nowaczyk, Tatiana Tomasi, Ekkehard Weber, Grzegorz Dworacki, Nils G. Morgenthaler, Heike Jansen, Corinna Propping, Karolina Sterzynska, Wojciech Dyszkiewicz, Maciej Zabel, Marion Kiechle, Ute Reuning, Manfred Schmitt, Klaus Lücke

Pages: 1241-1250 Published online on: 16 July 2012
Open Access

Radiofrequency currents exert cytotoxic effects in NB69 human neuroblastoma cells but not in peripheral blood mononuclear cells

María Luisa Hernández-Bule, Ernesto Roldán, Joaquín Matilla, María Ángeles Trillo, Alejandro Úbeda

Pages: 1251-1259 Published online on: 24 July 2012
Open Access

Differential expression of HIF-1 in glioblastoma multiforme and anaplastic astrocytoma

Arnulf Mayer, Fabienne Schneider, Peter Vaupel, Clemens Sommer, Heinz Schmidberger

Pages: 1260-1270 Published online on: 16 July 2012
Open Access

Simultaneous siRNA-mediated knockdown of antiapoptotic BCL2, Bcl-xL, XIAP and survivin in bladder cancer cells

Doreen Kunze, Kai Kraemer, Kati Erdmann, Michael Froehner, Manfred  P. Wirth, Susanne Fuessel

Pages: 1271-1277 Published online on: 06 July 2012

Inhibitory effect of PPARγ on NR0B1 in tumorigenesis of lung adenocarcinoma

Yoshiyuki Susaki, Masayoshi Inoue, Masato Minami, Noriyoshi Sawabata, Yasushi Shintani, Tomoyuki Nakagiri, Soichiro Funaki, Katsuyuki Aozasa, Meinoshin Okumura, Eiichi Morii

Pages: 1278-1284 Published online on: 25 July 2012

Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis

Minh‑Hue Nguyen, Koji Ueda, Yusuke Nakamura, Yataro Daigo

Pages: 1285-1296 Published online on: 10 August 2012

Phase I/II study of S-1 plus cisplatin combined with peptide vaccines for human vascular endothelial growth factor receptor 1 and 2 in patients with advanced gastric cancer

Toru Masuzawa, Yoshiyuki Fujiwara, Kaoru Okada, Ayumu Nakamura, Shuji Takiguchi, Kiyokazu Nakajima, Hiroshi Miyata, Makoto Yamasaki, Yukinori Kurokawa, Ryuji Osawa, Kazuyoshi Takeda, Koji Yoshida, Takuya Tsunoda, Yusuke Nakamura, Masaki Mori, Yuichiro Doki

Pages: 1297-1304 Published online on: 25 July 2012

Role of metallothionein 1E in the migration and invasion of human glioma cell lines

Hyang-Hwa Ryu, Shin Jung, Tae-Young Jung, Kyung-Sub Moon, In-Young Kim, Young-Il Jeong, Shu-Guang Jin, Jian Pei, Min Wen, Woo-Yeol Jang

Pages: 1305-1313 Published online on: 24 July 2012

Expression of cancer stem cell markers in pancreatic intraepithelial neoplasias and pancreatic ductal adenocarcinomas

Shoko Kure, Yoko Matsuda, Masahito Hagio, Junji Ueda, Zenya Naito, Toshiyuki Ishiwata

Pages: 1314-1324 Published online on: 23 July 2012

IDH1/2 mutation is a prognostic marker for survival and predicts response to chemotherapy for grade II gliomas concomitantly treated with radiation therapy

Yoshiko Okita, Yoshitaka Narita, Yasuji Miyakita, Makoto Ohno, Yuko Matsushita, Shintaro Fukushima, Minako Sumi, Koichi Ichimura, Takamasa Kayama, Soichiro Shibui

Pages: 1325-1336 Published online on: 20 July 2012

The BHLH transcription factor DEC1 plays an important role in the epithelial-mesenchymal transition of pancreatic cancer

Yunyan Wu, Fuyuki Sato, Toshiyuki Yamada, Ujjal Kumar Bhawal, Takeshi Kawamoto, Katsumi Fujimoto, Mitsuhide Noshiro, Hiroko Seino, Satoko Morohashi, Kenichi Hakamada, Yoshimitsu Abiko, Yukio Kato, Hiroshi Kijima

Pages: 1337-1346 Published online on: 18 July 2012

Loss of HITS (FAM107B) expression in cancers of multiple organs: tissue microarray analysis

Hideo Nakajima, Keita Koizumi, Takuji Tanaka, Yasuhito Ishigaki, Yoshino Yoshitake, Hideto Yonekura, Tsutomu Sakuma, Toshihiro Fukushima, Hisanori Umehara, Soichiro Ueno, Toshinari Minamoto, Yoshiharu Motoo

Pages: 1347-1357 Published online on: 10 July 2012

Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules

Jae Ju Jeong, Jae Heun Lee, Ki Churl Chang, Hye Jung Kim

Pages: 1358-1364 Published online on: 07 August 2012

Novel monoclonal antibodies specific for CTLD-SSC and sialomucin domains of endosialin, a mural cell marker of tumor vasculature

Soňa Kontseková, Anna Ohradanova Repic, Katarína Polčicová, Pauliina Tuomaala, Jaromír Pastorek, Silvia Pastoreková, Seppo Parkkila, Monika Baráthová

Pages: 1365-1372 Published online on: 23 July 2012

Expression of melanocortin receptors in human prostate cancer cell lines: MC2R activation by ACTH increases prostate cancer cell proliferation

Saly Hafiz, John C. Dennis, Dean Schwartz, Robert Judd, Ya‑Xiong Tao, Kamel Khazal, Benson Akingbemi, Xiu-Lei Mo, Asim B. Abdel‑Mageed, Edward Morrison, Mahmoud Mansour

Pages: 1373-1380 Published online on: 25 July 2012

The mTOR inhibitor RAD001 augments radiation-induced growth inhibition in a hepatocellular carcinoma cell line by increasing autophagy

Anaïs Altmeyer, Elodie Josset, Jean-Marc Denis, John  Gueulette, Jakobus  Slabbert, Didier Mutter, Georges Noël, Pierre  Bischoff

Pages: 1381-1386 Published online on: 07 August 2012

A smoking-associated 7-gene signature for lung cancer diagnosis and prognosis

Ying-Wooi Wan, Rebecca A. Raese, James E. Fortney, Changchang Xiao, Dajie Luo, John Cavendish, Laura F. Gibson, Vincent Castranova, Yong Qian, Nancy Lan Guo

Pages: 1387-1396 Published online on: 16 July 2012

Genomic CGH-assessed structural DNA alterations in rectal carcinoma as related to local recurrence following primary operation for cure

K. Kodeda, A. Gustafsson Asting, C. Lönnroth, K. Derwinger, Y. Wettergren, S. Nordgren, B. Gustavsson, K. Lundholm

Pages: 1397-1404 Published online on: 20 July 2012

A single nucleotide polymorphism in the human PIGK gene associates with low PIGK expression in colorectal cancer patients

Santanu Dasgupta, Prodipto Pal, Nitai D. Mukhopadhyay, Yumei Fu, Edward A. Ratovitski, Chul-So Moon, Mohammad Obaidul Hoque, Paul B. Fisher, Barry Trink

Pages: 1405-1410 Published online on: 23 July 2012

The Hedgehog signaling pathway in ovarian teratoma is stimulated by Sonic Hedgehog which induces internalization of Patched

Maja Sabol, Diana Car, Vesna Musani, Petar Ozretic, Slavko Oreskovic, Igor Weber, Sonja Levanat

Pages: 1411-1418 Published online on: 13 July 2012

Cytokine-like 1 is involved in the growth and metastasis of neuroblastoma cells

Mingjie Wen, Huanmin Wang, Xulong Zhang, Jun Long, Zhe Lv, Qingli Kong, Yunqing An

Pages: 1419-1424 Published online on: 13 July 2012

Antimycin A sensitizes cells to TRAIL-induced apoptosis through upregulation of DR5 and downregulation of c-FLIP and Bcl-2

Sung-Jun Lee, Eun-Ae Kim, Kyoung Seob Song, Min-Jae Kim, Dae Hyung Lee, Taeg Kyu Kwon, Tae-Jin Lee

Pages: 1425-1430 Published online on: 27 July 2012

Bufalin increases sensitivity to AKT/mTOR-induced autophagic cell death in SK-HEP-1 human hepatocellular carcinoma cells

Shih-Chang Tsai, Jai-Sing Yang, Shu-Fen Peng, Chi-Cheng Lu, Jo-Hua Chiang, Jing-Gung Chung, Meng-Wei Lin, Jen-Kun Lin, Sakae Amagaya, Cinderella Wai-Shan Chung, Theng-Thang Tung, Wen-Wen Huang, Michael T. Tseng

Pages: 1431-1442 Published online on: 31 July 2012

Etoposide induces a mixed type of programmed cell death and overcomes the resistance conferred by Bcl-2 in Hep3B hepatoma cells

Seung Hee Yoo, Young Geol Yoon, Jee Suk Lee, Yeon Suk Song, Joon Seok Oh, Bong Soo Park, Taeg Kyu Kwon, Cheol Park, Yung Hyun Choi, Young Hyun Yoo

Pages: 1443-1454 Published online on: 07 August 2012

Analysis of a novel highly metastatic melanoma cell line identifies osteopontin as a new lymphangiogenic factor

Ruediger Liersch, Jay W. Shin, Michael Bayer, Christian Schwöppe, Christoph Schliemann, Wolfgang E. Berdel, Rolf Mesters, Michael Detmar

Pages: 1455-1463 Published online on: 06 July 2012

Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells

Haley L. Peters, Amit Tuli, Xiaojian Wang, Cuiling Liu, Zenggang Pan, Michel M. Ouellette, Michael A. Hollingsworth, Richard G. MacDonald, Joyce C. Solheim

Pages: 1464-1474 Published online on: 13 July 2012

Inhibition of Aurora-B kinase activity confers antitumor efficacy in preclinical mouse models of early and advanced gastrointestinal neoplasia

Denis G. Alferez, Robert A. Goodlad, Rajesh Odedra, Patrizia  Sini, Claire  Crafter, Anderson J. Ryan, Stephen R. Wedge, Nicholas   A. Wright, Elizabeth Anderson, Robert W. Wilkinson

Pages: 1475-1485 Published online on: 31 July 2012

SAHA/Vorinostat induces the expression of the CD137 receptor/ligand system and enhances apoptosis mediated by soluble CD137 receptor in a human breast cancer cell line

Daniela Bellarosa, Alessandro Bressan, Mario Bigioni, Massimo Parlani, Carlo Alberto Maggi, Monica Binaschi

Pages: 1486-1494 Published online on: 13 July 2012

Arachidonic acid metabolism in human prostate cancer

Peiying Yang, Carrie A. Cartwright, Jin Li, Sijin Wen, Ina N. Prokhorova, Imad  Shureiqi, Patricia Troncoso, Nora M. Navone, Robert A. Newman, Jeri Kim

Pages: 1495-1503 Published online on: 10 August 2012

The enhanced antitumor effects of biodegradable cationic heparin-polyethyleneimine nanogels delivering HSulf-1 gene combined with cisplatin on ovarian cancer

Ping Liu, Maling Gou, Tao Yi, Xiaorong Qi, Chuan Xie, Shengtao Zhou, Hongxin Deng, Yuquan Wei, Xia Zhao

Pages: 1504-1512 Published online on: 18 July 2012

Antitumor effects of the novel quinazolinone MJ-33: Inhibition of metastasis through the MAPK, AKT, NF-κB and AP-1 signaling pathways in DU145 human prostate cancer cells

Mann-Jen Hour, Shih-Chang Tsai, Hsi-Chin Wu, Meng-Wei Lin, Jing‑Gung  Chung, Jin-Bin Wu, Jo-Hua Chiang, Minoru Tsuzuki, Jai-Sing Yang

Pages: 1513-1519 Published online on: 18 July 2012

Silencing of SNX1 by siRNA stimulates the ligand-induced endocytosis of EGFR and increases EGFR phosphorylation in gefitinib-resistant human lung cancer cell lines

Yukio Nishimura, Soichi Takiguchi, Kiyoko Yoshioka, Yusaku Nakabeppu, Kazuyuki Itoh

Pages: 1520-1530 Published online on: 31 July 2012

The NEDD8 conjugation pathway regulates p53 transcriptional activity and head and neck cancer cell sensitivity to ionizing radiation

Sébastien Guihard, Ludivine Ramolu, Christine Macabre, Bohdan  Wasylyk, Georges Noël, Joseph Abecassis, Alain C. Jung

Pages: 1531-1540 Published online on: 07 August 2012

Biological influence of brain-derived neurotrophic factor on breast cancer cells

Xiaomei Yang, Tracey A. Martin, Wen G. Jiang

Pages: 1541-1546 Published online on: 06 August 2012

Parthenolide suppresses tumor growth in a xenograft model of colorectal cancer cells by inducing mitochondrial dysfunction and apoptosis

Se-Lim Kim, Kieu The Thu Trang, Seong Hun Kim, In Hee Kim, Seung Ok Lee, Soo Teik Lee, Dae Ghon Kim, Sang-Wook Kim

Pages: 1547-1553 Published online on: 09 August 2012
Journal Cover

Cover Legend PDF

October 2012
Volume 41 Issue 4

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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