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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-October 2010 Volume 3 Issue 5

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

MMP-3 polymorphism: Genetic marker in pathological processes (Review)

F. B.A. Munhoz, A. L. Godoy-Santos, M. C.L.G. Santos
Pages: 735-740
Published online on: 26 July 2010

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Article Open Access

Polymorphisms of 5,10-methylenetetrahydrofolate reductase and thymidylate synthase in squamous cell carcinoma and basal cell carcinoma of the skin

Sang Yoon Kang, Sung Jun Lee, Seung Ho Hong, Yoon Kyu Chung, Hyun Soo Oh, Sug Won Kim, Dong Jin Yim, Nam Keun Kim
Pages: 741-747
Published online on: 08 July 2010

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Article Open Access

Secretory expression of Par-4 SAC-HA2TAT following adeno-associated virus-mediated gene transfer induces apoptosis in HepG2 cells

Tian-Jie Qin, Wei Ma, Shan-Xi Liu, Guang-Xiao Yang, Quan-Ying Wang, Xin-Han Zhao
Pages: 749-757
Published online on: 26 July 2010

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Article Open Access

Mutation of V896M in cardiac myosin binding protein-c gene in two Chinese families with hypertrophic cardiomyopathy

Ai-ling Wang, De-hua Kong, Duo-xue Chen, Jun Wan, Yuan-xun Yu
Pages: 759-763
Published online on: 20 July 2010

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Article Open Access

Responses to surgical stress after esophagectomy: Gene expression of heat shock protein 70, toll-like receptor 4, tumor necrosis factor-α and inducible nitric oxide synthase

Satoshi Suzuki, Hiroshi Morimatsu, Emiko Omori, Hiroko Shimizu, Toru Takahashi, Tomoki Yamatsuji, Yoshio Naomoto, Kiyoshi Morita
Pages: 765-769
Published online on: 20 July 2010

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Article

Administration of the selective cyclooxygenase (COX)-2 inhibitor etodolac prolongs cardiac allograft survival in a mouse model

Masahide Matsuyama, Rikio Yoshimura, Taro Hase, Jamel Chargui, Norio Yoshimura, Jean-Louis Touraine
Pages: 771-774
Published online on: 26 July 2010

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Article

Methylation status of the PTEN gene in adenoid cystic carcinoma cells

Xiaoping Fan, Bin Chen, Junli Xu, Huachang Zhang, Feng Deng, Xuerong Xiang
Pages: 775-779
Published online on: 26 July 2010

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Article

Down-regulation of annexin II in prostate cancer is associated with Gleason score, recurrence, metastasis and poor prognosis

Tao Ding, Luoyan Yang, Yinhuai Wang, Junbin Yuan, Tieding Chen, Xiaojian Cai
Pages: 781-787
Published online on: 20 July 2010

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Article

Cetuximab-induced skin exanthema: Improvement by a reactive skin therapy

Carl C. Schimanski, Markus Moehler, Tim Zimmermann, Markus A. Wörns, Alma Steinbach, Michael Baum, Peter R. Galle
Pages: 789-793
Published online on: 20 July 2010

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Article

Zeranol enhances leptin-induced proliferation in primary cultured human breast cancer epithelial cells

Pingping Xu, Weiping Ye, Hong Li, Shu-Hong Lin, Chieh-Ti Kuo, Eric Feng, Young C. Lin
Pages: 795-800
Published online on: 26 July 2010

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Article

Knockdown of Beclin 1 inhibits vitamin K3‑induced autophagy, but promotes apoptosis of human hepatoma SMMC-7721 cells

Chuang Yang, Li-Ou Han
Pages: 801-807
Published online on: 26 July 2010

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Article

Modulation of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in RAW264.7 cells by irradiation

Y. Zhou, L. Xia, Z. S. He, W. Ouyang, H. Z, C. H. Xie
Pages: 809-813
Published online on: 08 July 2010

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Article

Actin disruption inhibits hypoxia inducible factor-1α expression via inactivity of Mdm2-mediated p70S6K

Ik Jae Shin, Bae Keun Park, Yong-Tae Ahn, Yongkuk Kim, Won G. An
Pages: 815-819
Published online on: 08 July 2010

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Article

Mass spectrometry-based proteomic analysis of Kashin-Beck disease

Jianqiang Du, Xiaomin Wu, Huqin Zhang, Shuang Wang, Wuhong Tan, Xiong Guo
Pages: 821-824
Published online on: 08 July 2010

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Article

20(S)-Ginsenoside Rg3-induced apoptosis in HT-29 colon cancer cells is associated with AMPK signaling pathway

Hai-Dan Yuan, Hai-Yan Quan, Ya Zhang, Sung Hoon Kim, Sung-Hyun Chung
Pages: 825-831
Published online on: 08 July 2010

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Article

Modulation of small molecule solubility and protein binding by arginine

Tsutomu Arakawa, Misao Uozaki, A. Hajime Koyama
Pages: 833-836
Published online on: 20 July 2010

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Article

Genetic variants in the distal enhancer region of the PSA gene and their implication in the occurrence of advanced prostate cancer

Sushant V. Chavan, Anurupa Maitra, Nobhojit Roy, Sujata Patwardhan, Padma R. Chavan
Pages: 837-843
Published online on: 26 July 2010

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Article

Involvement of the expression and redistribution of claudin-23 in pancreatic cancer cell dissociation

Wei Wang, Xiaodong Tan, Lei Zhou, Feng Gao, Xianwei Dai
Pages: 845-850
Published online on: 20 July 2010

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Article

Novel anti-leukemia activities of pipoxolan operate via the mitochondria-related pathway in human leukemia U937 cells and attenuate U937 cell growth in an animal model

Yuh-Fung Chen, Jia-Sing Yang, Wen-Wen Huang, Huei-Yann Tsai
Pages: 851-856
Published online on: 08 July 2010

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Article

Down-regulation of the global regulator SATB1 by statins in COLO205 colon cancer cells

C. N. Lakshminarayana Reddy, V. N. Vyjayanti, Dimple Notani, Sanjeev Galande, Srigiridhar Kotamraju
Pages: 857-861
Published online on: 26 July 2010

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Article

Clinicopathological features of breast cancer patients with nipple discharge

Wen-Jin Yin, Gen-Hong Di, Guang-Yu Liu, Jiong Wu, Jin-Song Lu, Qi-Xia Han, Zhen-Zhou Shen, Zhi-Min Shao
Pages: 863-868
Published online on: 26 July 2010

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Article

Protective effect of hypoxia on bisphosphonate‑related bone cell damage

Myung-Hee Moon, Jae-Won Seol, Jae-Suk Seo, Jae-Kyo Jeong, You-Jin Lee, In-Shik Kim, Chris Jackson, Philip Sambrook, Sang-Youel Park
Pages: 869-875
Published online on: 26 July 2010

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Article

Transcriptional regulation of 1-cys peroxiredoxin by the proto-oncogene protein DEK

Dong-Wook Kim, Ji-Young Kim, Sulji Choi, Sangmyung Rhee, Yoonsoo Hahn, Sang-Beom Seo
Pages: 877-881
Published online on: 26 July 2010

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Article

Promoter methylation profile of GSTP1 and RASSF1A in benign hyperplasia and metastatic prostate cancer patients in a Kashmiri population

Nidda Syeed, A. Syed Sameer, Arif Hamid, Zafar A. Shah, Dil Afroze, Roohi Rasool, Mushtaq A. Siddiqi
Pages: 883-887
Published online on: 26 July 2010

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Journal Cover
July-2026 Volume 34 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Editorial Open Access

Regulatory mechanisms and therapeutic potential of N6-methyladenosine modification in retinal diseases (Review)

Wenyao Zhang, Jinying Chen, Jingxiang Zhong
Article Number: 213
Published online on: 29 May 2026

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Review Open Access

Epigenetic orchestration of scar formation: Therapeutic potential of targeting DNA methylation and non‑coding RNAs in cutaneous fibrosis (Review)

Jinshun Li, Weiyun Liu, Jin Yang, Yanan Li
Article Number: 212
Published online on: 29 May 2026

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Review Open Access

Elucidating the multitarget neuroprotective mechanisms of protocatechuic acid in neurological disorders (Review)

Xiaoyan Xue, Yongchang Lai, Shasha Song, Liping Wu, Lifang Wang
Article Number: 211
Published online on: 29 May 2026

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Retraction Open Access

[Retracted] Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP‑9 signaling pathway in DU145 cells

Yuan Zeng, Ying Yang
Article Number: 210
Published online on: 27 May 2026

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Article Open Access

FOSL2 drives transcriptional activation of super‑enhancer-regulated DYNC1H1 to promote hypoxia‑induced oral squamous cell carcinoma progression

Linyu Jin, Jing Zhang, Wenjing Wang, Nan Zhang, Yang Liu, Alin Tian, Weiwei Yin, Yongle Qiu
Article Number: 209
Published online on: 25 May 2026

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Review Open Access

Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Review Open Access

Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Review Open Access

Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
Published online on: 22 May 2026

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Review Open Access

Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Review Open Access

Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Review Open Access

Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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Article Open Access

ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng, Bin Yang
Article Number: 202
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Review Open Access

Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Review Open Access

Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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Review Open Access

m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Review Open Access

Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Review Open Access

Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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Article Open Access

NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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Review Open Access

POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Review Open Access

Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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Retraction Open Access

[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Review Open Access

Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Article Open Access

Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Review Open Access

Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Review Open Access

Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Review Open Access

Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Article Open Access

Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 34 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Retraction Open Access

[Retracted] Tripterygium glycoside suppresses epithelial‑to‑­­ mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Mei Tao, Danna Zheng, Xudong Liang, Diandian Wu, Kang Hu, Juan Jin, Qiang He
Article Number: 225
Published online on: 08 June 2026

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Review Open Access

Gut microbiota‑derived metabolites in cardiovascular disease: Focus on trimethylamine N‑oxide, short‑chain fatty acids and bile acids (Review)

Meizhu Gao, Zhenming Hao, Yiling Li, Weixue Liu, Fubao Zhang
Article Number: 224
Published online on: 08 June 2026

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Article Open Access

Fucoxanthin alleviates chondrocyte inflammation and osteoarthritis by modulating the JAK2/STAT3 signaling pathway

Miradj Siddick Adam, Huangming Zhuang, Xunshan Ren, Yuelong Zhang, Panghu Zhou
Article Number: 223
Published online on: 08 June 2026

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Article Open Access

Prediction of molecular targets for zedoary turmeric oil in inhibiting proliferation and inducing apoptosis in non‑small cell lung cancer

Huaiyong Li, Lili Liu, Qingzhu Yang, Yao Li, Yongli Song, Jing Jiang, Zhenzhong Wu, Weiwei Zhang, Baisong Lou
Article Number: 222
Published online on: 08 June 2026

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Molecular mechanisms of iron metabolism and ferroptosis in cardiovascular diseases and intervention strategies targeting natural products (Review)

Liangqing Ge, Tianqing Zhang, Jiangbiao Yu, Sijie Xiao, Yu Zhou, Li Luo
Article Number: 221
Published online on: 05 June 2026

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Correction Open Access

[Corrigendum] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 220
Published online on: 03 June 2026

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LINC01117 promotes the malignant proliferation of lung adenocarcinoma by increasing HOXD8 mRNA stability

Lizhong Zeng, Jie Shi, Cai Zhang, Yujiao Dong, Yang Chen, Qiuhong Zhang, Long Zhang, Shuanying Yang
Article Number: 219
Published online on: 03 June 2026

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Article Open Access

Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review)

Hua Luo
Article Number: 218
Published online on: 03 June 2026

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Article Open Access

Dapagliflozin alleviates heart failure with preserved ejection fraction potentially by regulating the AIM2/caspase‑1/GSDMD pathway and attenuating pyroptosis

Sailiang Ding, Hao Yang, Ting Lu, Yibin Luo, Liang Xu, Xianghui Zeng
Article Number: 217
Published online on: 03 June 2026

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Retraction Open Access

[Retracted] Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models

Yong Liu, Yan Zhang, Ming Hu, Yu-Hu Li, Xing-Hua Cao
Article Number: 216
Published online on: 02 June 2026

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SIRT1/AMPK/PGC1α pathway in ischemic stroke: Elucidating neuroprotective strategies (Review)

Irum Naz Abbasi, Nashwa Amin, Qiaolu Xu, Azhar Badry Hussain, Fei Wu, Xia Yuan, Yang Yang, Suhong Ye, Marong Fang, Yihua Jiang
Article Number: 215
Published online on: 02 June 2026

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Review Open Access

Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)

Yinhuan Wang, Jiefang Guan
Article Number: 214
Published online on: 29 May 2026

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