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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2025 Volume 31 Issue 4

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Therapeutic potential of flavonoids in gastrointestinal cancer: Focus on signaling pathways and improvement strategies (Review)

Ye Ding, Yong Yu
Article Number: 109
Published online on: 24 February 2025

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Article Open Access

CIP2A promotes bronchiolitis obliterans by activating the NF‑κB pathway

Xu Zhou, Xingyou Zhao, Yanning Li, Baoqing Zhang
Article Number: 108
Published online on: 24 February 2025

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Review Open Access

α‑1 Antitrypsin is a potential target of inflammation and immunomodulation (Review)

Tiantian Wang, Peimeng Shuai, Qingyu Wang, Caimao Guo, Shuqi Huang, Yuanyuan Li, Wenyu Wu, Lan Yi
Article Number: 107
Published online on: 24 February 2025

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Underlying mechanisms and treatment of acetaminophen‑induced liver injury (Review)

Ruisi Li, Haojia Wu, Yue Xu, Xiaoying Xu, Yiheng Xu, Haitang Huang, Xiaojuan Lv, Chu Liao, Junqiu Ye, Hengfei Li
Article Number: 106
Published online on: 24 February 2025

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Mechanisms and preventive measures of ALDH2 in ischemia‑reperfusion injury: Ferroptosis as a novel target (Review)

Liang Han, Wen Zhai
Article Number: 105
Published online on: 21 February 2025

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Article Open Access

Role of the integrin‑β1/TGF‑β1 signaling pathway in the pathogenesis of pelvic organ prolapse: A study on vaginal wall tissue alterations and molecular dysfunction

Min Kong, Zhuo Wang, Yao Hao, Yueyue Shi, Xin Yang, Ngenzi Richard Djurist, Yan Li
Article Number: 104
Published online on: 20 February 2025

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Review Open Access

Research progress of cPLA2 in cardiovascular diseases (Review)

Wenyu Lin, Shuya Wang, Ronghan Liu, Dan Zhang, Jiaxing Zhang, Xiaohan Qi, Zheng Li, Meng Miao, Xiaojun Cai, Guohai Su
Article Number: 103
Published online on: 19 February 2025

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Review Open Access

Hydroxychloroquine: A double‑edged sword (Review)

Rongxiu Huo, Chengcheng Wei, Yanting Yang, Jinying Lin, Xinxiang Huang
Article Number: 102
Published online on: 19 February 2025

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The key role of miR‑378 in kidney diseases (Review)

Yangyang Liu, Shuqing Shi, Tao Cheng, Haoshuo Wang, Huan Wang, Yuanhui Hu
Article Number: 101
Published online on: 19 February 2025

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Article Open Access

Recombinant human collagen XVII protects skin basement membrane integrity by inhibiting the MAPK and Wnt signaling pathways

Jing Wang, Simin Lin, Yun Wei, Zhangying Ye
Article Number: 100
Published online on: 19 February 2025

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Article Open Access

PLEKHA4 knockdown induces apoptosis in melanoma cells through the MAPK and β‑catenin signaling pathways

Yuyang Yue, Guangqi An, Shuxia Cao, Xiangdan Li, Liping Du, Dongyuan Xu, Lan Liu
Article Number: 99
Published online on: 18 February 2025

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Mechanisms of microplastics on gastrointestinal injury and liver metabolism disorder (Review)

Li Zhou, Lidan Ran, Yufen He, Yaxi Huang
Article Number: 98
Published online on: 18 February 2025

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Article Open Access

N‑acetyl‑L‑cysteine protects rat lungs and RLE‑6TN cells from cigarette smoke‑induced oxidative stress

Jiameng Chen, Yuefeng Cheng, Huijuan Cui, Shuangyan Li, Lantian Duan, Zongxian Jiao
Article Number: 97
Published online on: 18 February 2025

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Retraction Open Access

[Retracted] Upregulation of Stat1‑HDAC4 confers resistance to etoposide through enhanced multidrug resistance 1 expression in human A549 lung cancer cells

Chutima Kaewpiboon, Ratakorn Srisuttee, Waraporn Malilas, Jeong Moon, Sangtaek Oh, Hye Gwang Jeong, Randal N. Johnston, Wanchai Assavalapsakul, Young-Hwa Chung
Article Number: 96
Published online on: 17 February 2025

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Article Open Access

Mechanism of β‑sitosterol in treating keloids: Network pharmacology, molecular docking and experimental verification

Pingping Huo, Zhouna Li, Shan Jin, Sujie Wang, Yinli Luo, Lianhua Zhu, Zhehu Jin
Article Number: 95
Published online on: 14 February 2025

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Exosomal miR‑3681‑3p from M2‑polarized macrophages confers cisplatin resistance to gastric cancer cells by targeting MLH1

Wujun Wei, Jiaxing Li, Jingjing Huang, Qi Jiang, Cheng Lin, Rentong Hu, Jiazhu Wei, Qiao Li, Guidan Xu, Zhengyi Chang
Article Number: 94
Published online on: 14 February 2025

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Article Open Access

Identification and validation of biomarkers related to mitophagy in chronic obstructive pulmonary disease

Jie Chen, Xiaofeng Zhang, Gengyun Sun
Article Number: 93
Published online on: 11 February 2025

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Retraction Open Access

[Retracted] lncRNA FGD5‑AS1 promotes breast cancer progression by regulating the hsa‑miR‑195‑5p/NUAK2 axis

Kun Fang, Zheng-Jie Xu, Su-Xiao Jiang, De-Sheng Tang, Chang-Sheng Yan, You-Yuan Deng, Fu-Ying Zhao
Article Number: 92
Published online on: 10 February 2025

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Potential of lactylation as a therapeutic target in cancer treatment (Review)

Zhengfeng Zhu, Xinzhe Zheng, Pengfei Zhao, Cheng Chen, Gang Xu, Xixian Ke
Article Number: 91
Published online on: 07 February 2025

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Modic changes: From potential molecular mechanisms to future research directions (Review)

Weijian Zhu, Zhou Yang, Sirui Zhou, Jinming Zhang, Zhihao Xu, Wei Xiong, Ping Liu
Article Number: 90
Published online on: 06 February 2025

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Retraction Open Access

[Retracted] Metastasis‑associated protein 2 promotes the metastasis of non‑small cell lung carcinoma by regulating the ERK/AKT and VEGF signaling pathways

Bin Zhang, Feng Tao, Hao Zhang
Article Number: 89
Published online on: 06 February 2025

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Article Open Access

Evaluation of the protective effect of Compound Kushen Injection against radiation‑induced lung injury in mice

Ting Xu, Sharmistha Chakraborty, Daoyan Wei, Megan Tran, Robyn Rhea, Bo Wei, Phuong Nguyen, Mihai Gagea, Xiaoxue Xie, Lirong Wu, Lorenzo Cohen, Zhongxing Liao, Peiying Yang
Article Number: 88
Published online on: 05 February 2025

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The protective effects and mechanism of myricetin in liver diseases (Review)

Mi Chen, Shengnan Zhang, Xingqiong Huang, Dandan Zhang, Dan Zhu, Changhan Ouyang, Yankun Li
Article Number: 87
Published online on: 03 February 2025

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Lipid mediators obtained from docosahexaenoic acid by soybean lipoxygenase alleviate ovalbumin‑induced allergic asthma in mice by reducing airway inflammation and oxidative stress

Yan Su, Hack Sun Choi, Soon Kyu Kwon, Yunjon Han, Soon-Chang Cho, Jin Hyuk Shin, Yong-Suk Jang, Jong Hyun Choi, Jeong-Woo Seo
Article Number: 86
Published online on: 03 February 2025

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Article Open Access

Protective effect of soluble protein hydrolysate against H2O2‑induced intestinal injury: An interventional study

Jingjing Wei, Guozhong Tao, Junlin Liu, Bomi Framroze, Karl G. Sylvester
Article Number: 85
Published online on: 29 January 2025

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Retraction Open Access

[Retracted] AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway

Xianjun Wang, Baocheng Yang, Yuyu Li, Jiye Luo, Yanli Wang
Article Number: 84
Published online on: 29 January 2025

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Adaptation mechanisms in cancer: Lipid metabolism under hypoxia and nutrient deprivation as a target for novel therapeutic strategies (Review)

Shiro Koizume, Yohei Miyagi
Article Number: 83
Published online on: 28 January 2025

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Article Open Access

Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Article Open Access

Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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Article Open Access

ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Article Open Access

Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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Article Open Access

CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Article Open Access

Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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Journal Cover
March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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