Journal Articles

Open Access

Upregulated expression of MMP family genes is associated with poor survival in patients with esophageal squamous cell carcinoma via regulation of proliferation and epithelial‑mesenchymal transition

Guifeng Xu, Ling Ou, Ying Liu, Xiao Wang, Kaisheng Liu, Jieling Li, Junjun Li, Shaoqi Wang, Dane Huang, Kai Zheng, Shaoxiang Wang

Pages: 29-42 Published online on: 07 May 2020
Open Access

TIRC7 inhibits Th1 cells by upregulating the expression of CTLA‑4 and STAT3 in mice with acute graft‑versus‑host disease

Feng Zhu, Tingting Qiu, Shengyun Zhu, Kai Zhao, Chong Chen, Jianlin Qiao, Bin Pan, Zhiling Yan, Wei Chen, Qiong Liu, Qingyun Wu, Jiang Cao, Wei Sang, Lingyu Zeng, Haiying Sun, Zhenyu Li, Kailin Xu

Pages: 43-54 Published online on: 21 April 2020
Open Access

Increased expression of RBMS3 predicts a favorable prognosis in human gallbladder carcinoma

Youliang Wu, Delong Meng, Yexiang You, Ruochuan Sun, Qiang Yan, Junjun Bao, Yanjun Sun, Dapeng Yun, Yongxiang Li, Dengqun Sun

Pages: 55-68 Published online on: 23 April 2020
Open Access

Kindlin‑2 suppresses cervical cancer cell migration through AKT/mTOR‑mediated autophagy induction

Guangteng Wu, Ying Long, Yan Lu, Yiming Feng, Xinmei Yang, Xun Xu, Desheng Yao

Pages: 69-76 Published online on: 04 May 2020
Open Access

DJ‑1 is a new prognostic marker and predicts chemotherapy efficacy in colorectal cancer

Weimin Wang, Haibo Wang, Liangliang Xiang, Tengyang Ni, Feng Jin, Jianliang Deng, Yunlei Zhang, Ishikawa Shintaro, Yan Zhou, Yanqing Liu

Pages: 77-90 Published online on: 23 April 2020
Open Access

Ciprofloxacin promotes polarization of CD86+CD206‑ macrophages to suppress liver cancer

Mengtian Fan, Sicheng Chen, Yaguang Weng, Xian Li, Yingjiu Jiang, Xiaowen Wang, Mengjun Bie, Liqin An, Menghao Zhang, Bin Chen, Gaigai Huang, Jinghong Wu, Mengying Zhu, Qiong Shi

Pages: 91-102 Published online on: 29 April 2020
Open Access

Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway

Xianke Yan, Chao Yang, Wei Hu, Tao Chen, Qi Wang, Feng Pan, Bing Qiu, Bensen Tang

Pages: 103-114 Published online on: 12 May 2020
Open Access

NEAT1 knockdown suppresses endothelial cell proliferation and induces apoptosis by regulating miR‑638/AKT/mTOR signaling in atherosclerosis

Xia Zhang, Ming‑Xiu Guan, Qiu‑Hong Jiang, Sai Li, Hong‑Yu Zhang, Zhi‑Guo Wu, Hong‑Liang Cong, Xiu‑Hui Qi

Pages: 115-125 Published online on: 07 May 2020
Open Access

VL30 retrotransposition is associated with induced EMT, CSC generation and tumorigenesis in HC11 mouse mammary stem‑like epithelial cells

Soteroula Thrasyvoulou, Georgios Vartholomatos, Georgios Markopoulos, Dimitrios Noutsopoulos, Stefania Mantziou, Foteini Gkartziou, Panagiotis Papageorgis, Antonia Charchanti, Panos Kouklis, Andreas I. Constantinou, Theodore Tzavaras

Pages: 126-138 Published online on: 28 April 2020
Open Access

miR‑193b exhibits mutual interaction with MYC, and suppresses growth and metastasis of osteosarcoma

Jinjian Gao, Sai Ma, Fan Yang, Xu Chen, Wei Wang, Jianping Zhang, Yufang Li, Tao Wang, Lequn Shan

Pages: 139-155 Published online on: 29 April 2020
Open Access

An elongated tract of polyQ in the carboxyl‑terminus of human α1A calcium channel induces cell apoptosis by nuclear translocation

Ji Sun, Xiguang Sun, Zhuo Li, Dihui Ma, Yudan Lv

Pages: 156-164 Published online on: 22 April 2020
Open Access

Long non‑coding RNA H19 is involved in sorafenib resistance in hepatocellular carcinoma by upregulating miR‑675

Yongzi Xu, Yanhui Liu, Zhenrong Li, Hao Li, Xiqing Li, Lei Yan, Jiayan Mao, Jian Shen, Wei Chen, Fei Xue

Pages: 165-173 Published online on: 08 May 2020
Open Access

Spred2 inhibits epithelial‑mesenchymal transition of colorectal cancer cells by impairing ERK signaling

Hao Wang, Shuchen Liu, Fanxuan Kong, Fengjun Xiao, Yuxiang Li, Hua Wang, Shun Zhang, Dandan Huang, Lisheng Wang, Yuefeng Yang

Pages: 174-184 Published online on: 16 April 2020
Open Access

The miR‑625‑3p/AXL axis induces non‑T790M acquired resistance to EGFR‑TKI via activation of the TGF‑β/Smad pathway and EMT in EGFR‑mutant non‑small cell lung cancer

Wenwen Du, Lin Sun, Ting Liu, Jianjie Zhu, Yuanyuan Zeng, Yang Zhang, Xueting Wang, Zeyi Liu, Jian‑An Huang

Pages: 185-195 Published online on: 08 April 2020
Open Access

Morpho‑functional study of the hypothalamic proline‑rich polypeptide apoptotic activity against mouse Ehrlich ascites carcinoma

S. Abrahamyan, I. Sahakyan, N. Tumasyan, N. Kocharyan, A. Simonyan, R. Aroutiounian, G. Chailyan, S. Chailyan, T. Davtyan, K. Galoian

Pages: 196-212 Published online on: 04 May 2020
Open Access

RAD18 promotes colorectal cancer metastasis by activating the epithelial‑mesenchymal transition pathway

Peng Li, Chao He, Aidi Gao, Xueqi Yan, Xiaochun Xia, Jundong Zhou, Jinchang Wu

Pages: 213-223 Published online on: 21 April 2020
Open Access

Exploration of the personalized immune checkpoint atlas of plasma cell dyscrasias patients using high‑dimensional single‑cell analysis

Chenggong Tu, Yongjiang Zheng, Hui Zhang, Jinheng Wang

Pages: 224-240 Published online on: 21 April 2020
Open Access

1‑Palmitoyl‑2‑linoleoyl‑3‑acetyl‑rac‑glycerol ameliorates EGF‑induced MMP‑9 expression by promoting receptor desensitization in MDA‑MB‑231 cells

Kwang Hoon Yang, Guen Tae Kim, Solji Choi, Sun Young Yoon, Jae Wha Kim

Pages: 241-251 Published online on: 28 April 2020
Open Access

High expression levels of polymeric immunoglobulin receptor are correlated with chemoresistance and poor prognosis in pancreatic cancer

Ryotaro Ohkuma, Erica Yada, Shumpei Ishikawa, Daisuke Komura, Yutaro Kubota, Kazuyuki Hamada, Atsushi Horiike, Tomoyuki Ishiguro, Yuya Hirasawa, Hirotsugu Ariizumi, Midori Shida, Makoto Watanabe, Rie Onoue, Kiyohiro Ando, Junji Tsurutani, Kiyoshi Yoshimura, Tetsuro Sasada, Takeshi Aoki, Masahiko Murakami, Tomoko Norose, Nobuyuki Ohike, Masafumi Takimoto, Shinichi Kobayashi, Takuya Tsunoda, Satoshi Wada

Pages: 252-262 Published online on: 11 May 2020

RET receptor expression and interaction with TRK receptors in neuroblastomas

Laura H. Tetri, Venkatadri Kolla, Rebecca L. Golden, Radhika Iyer, Jamie L. Croucher, Jee‑Hye Choi, Suzanne P. Macfarland, Koumudi Naraparaju, Peng Guan, Ferro Nguyen, Krutika S. Gaonkar, Pichai Raman, Garrett M. Brodeur

Pages: 263-272 Published online on: 15 April 2020

Novel SAHA‑bendamustine hybrid NL‑101 in combination with daunorubicin synergistically suppresses acute myeloid leukemia

Jingrui Jin, Xia Li, Wenjian Guo, Fenglin Li, Jiansong Huang, Xin Huang, Jiajia Pan, Shujuan Huang, Wenle Ye, Qing Ling, Jie Jin

Pages: 273-282 Published online on: 22 April 2020

Effect of the natural compound trans‑resveratrol on human MCM4 gene transcription

Fumiaki Uchiumi, Chihiro Katsuda, Motohiro Akui, Monami Kusaka, Marie Tanaka, Masashi Asai, Sei‑Ichi Tanuma

Pages: 283-292 Published online on: 28 April 2020

Role of glucose metabolism in the differential antileukemic effect of melatonin on wild‑type and FLT3‑ITD mutant cells

Noelia Puente‑Moncada, Maria Turos‑Cabal, Ana M. Sánchez‑Sánchez, Isaac Antolín, Federico Herrera, Jezabel Rodriguez‑Blanco, Cristina Duarte‑Olivenza, Carmen Rodriguez, Vanesa Martín

Pages: 293-302 Published online on: 15 April 2020

The effects of the Wnt/β‑catenin signaling pathway on apoptosis in HeLa cells induced by carbon ion irradiation

Jing Si, Jinhua Zhang, Lu Gan, Menghuan Guo, Yi Xie, Cuixia Di, Chao Sun, Fang Wang, Junfang Yan, Hong Zhang

Pages: 303-312 Published online on: 10 April 2020

Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran

Pages: 313-324 Published online on: 28 April 2020

Fluctuating role of antimicrobial peptide hCAP18/LL‑37 in oral tongue dysplasia and carcinoma

Marlene Vierthaler, Priscila Campioni Rodrigues, Elias Sundquist, Maria Siponen, Tuula Salo, Maija Risteli

Pages: 325-338 Published online on: 11 May 2020

Antihypertensive drug telmisartan suppresses the proliferation of gastric cancer cells in vitro and in vivo

Naoki Fujita, Koji Fujita, Hisakazu Iwama, Hideki Kobara, Shintaro Fujihara, Taiga Chiyo, Daisuke Namima, Hiroki Yamana, Toshiaki Kono, Kei Takuma, Masahiro Hirata, Kiyoyuki Kobayashi, Kiyohito Kato, Hideki Kamada, Asahiro Morishita, Kunihiko Tsutsui, Takashi Himoto, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki

Pages: 339-348 Published online on: 07 May 2020

Long non‑coding RNA GHET1 promotes osteosarcoma development and progression via Wnt/β‑catenin signaling pathway

Xingli Chen, Wei Zhao, Weimin Fan

Pages: 349-359 Published online on: 16 April 2020

Icariside II overcomes BRAF inhibitor resistance in melanoma by inducing ROS production and inhibiting MITF

Xiao Liu, Zheng Li, Ming Li, Jingxiu Chai, Shan He, Jinfeng Wu, Jinhua Xu

Pages: 360-370 Published online on: 15 April 2020

Metformin inhibits TGF‑β1‑induced epithelial‑mesenchymal transition and liver metastasis of pancreatic cancer cells

Juichiro Yoshida, Takeshi Ishikawa, Yuki Endo, Shinya Matsumura, Takayuki Ota, Katsura Mizushima, Yasuko Hirai, Kaname Oka, Tetsuya Okayama, Naoyuki Sakamoto, Ken Inoue, Kazuhiro Kamada, Kazuhiko Uchiyama, Tomohisa Takagi, Yuji Naito, Yoshito Itoh

Pages: 371-381 Published online on: 23 April 2020

Curcumin inhibits pancreatic cancer cell invasion and EMT by interfering with tumor‑stromal crosstalk under hypoxic conditions via the IL‑6/ERK/NF‑κB axis

Wei Li, Liankang Sun, Jianjun Lei, Zheng Wu, Qingyong Ma, Zheng Wang

Pages: 382-392 Published online on: 28 April 2020

Proline‑rich polypeptide‑1 decreases cancer stem cell population by targeting BAFF chromatin‑remodeling complexes in human chondrosarcoma JJ012 cells

Alexandra Moran, Aaron Hoyt, Anil Sedani, Caroline Granger, Shannon Saigh, Marzenna Blonska, Liu Zhao‑Ju, Sheila Ann Conway, Juan Pretell, Jeffrey Brown, Karina Galoian

Pages: 393-403 Published online on: 14 May 2020
Journal Cover

July-2020
Volume 44 Issue 1

Print ISSN: 1021-335X
Online ISSN: 1791-2431

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