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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2020 Volume 44 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Molecularly targeted therapy and immunotherapy for hormone receptor‑positive/human epidermal growth factor receptor 2‑negative advanced breast cancer (Review)

Yuhua Song, Lin He, Yaling Wang, Qian Wu, Wenzhi Huang
Pages: 3-13
Published online on: 21 April 2020

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Article Open Access

HDGF enhances VEGF‑dependent angiogenesis and FGF‑2 is a VEGF‑independent angiogenic factor in non‑small cell lung cancer

Ryoji Eguchi, Ichiro Wakabayashi
Pages: 14-28
Published online on: 09 April 2020

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Article Open Access

Upregulated expression of MMP family genes is associated with poor survival in patients with esophageal squamous cell carcinoma via regulation of proliferation and epithelial‑mesenchymal transition

Guifeng Xu, Ling Ou, Ying Liu, Xiao Wang, Kaisheng Liu, Jieling Li, Junjun Li, Shaoqi Wang, Dane Huang, Kai Zheng, Shaoxiang Wang
Pages: 29-42
Published online on: 07 May 2020

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Article Open Access

TIRC7 inhibits Th1 cells by upregulating the expression of CTLA‑4 and STAT3 in mice with acute graft‑versus‑host disease

Feng Zhu, Tingting Qiu, Shengyun Zhu, Kai Zhao, Chong Chen, Jianlin Qiao, Bin Pan, Zhiling Yan, Wei Chen, Qiong Liu, Qingyun Wu, Jiang Cao, Wei Sang, Lingyu Zeng, Haiying Sun, Zhenyu Li, Kailin Xu
Pages: 43-54
Published online on: 21 April 2020

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Article Open Access

Increased expression of RBMS3 predicts a favorable prognosis in human gallbladder carcinoma

Youliang Wu, Delong Meng, Yexiang You, Ruochuan Sun, Qiang Yan, Junjun Bao, Yanjun Sun, Dapeng Yun, Yongxiang Li, Dengqun Sun
Pages: 55-68
Published online on: 23 April 2020

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Article Open Access

Kindlin‑2 suppresses cervical cancer cell migration through AKT/mTOR‑mediated autophagy induction

Guangteng Wu, Ying Long, Yan Lu, Yiming Feng, Xinmei Yang, Xun Xu, Desheng Yao
Pages: 69-76
Published online on: 04 May 2020

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Article Open Access

DJ‑1 is a new prognostic marker and predicts chemotherapy efficacy in colorectal cancer

Weimin Wang, Haibo Wang, Liangliang Xiang, Tengyang Ni, Feng Jin, Jianliang Deng, Yunlei Zhang, Ishikawa Shintaro, Yan Zhou, Yanqing Liu
Pages: 77-90
Published online on: 23 April 2020

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Article Open Access

Ciprofloxacin promotes polarization of CD86+CD206‑ macrophages to suppress liver cancer

Mengtian Fan, Sicheng Chen, Yaguang Weng, Xian Li, Yingjiu Jiang, Xiaowen Wang, Mengjun Bie, Liqin An, Menghao Zhang, Bin Chen, Gaigai Huang, Jinghong Wu, Mengying Zhu, Qiong Shi
Pages: 91-102
Published online on: 29 April 2020

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Article Open Access

Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway

Xianke Yan, Chao Yang, Wei Hu, Tao Chen, Qi Wang, Feng Pan, Bing Qiu, Bensen Tang
Pages: 103-114
Published online on: 12 May 2020

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Article Open Access

NEAT1 knockdown suppresses endothelial cell proliferation and induces apoptosis by regulating miR‑638/AKT/mTOR signaling in atherosclerosis

Xia Zhang, Ming‑Xiu Guan, Qiu‑Hong Jiang, Sai Li, Hong‑Yu Zhang, Zhi‑Guo Wu, Hong‑Liang Cong, Xiu‑Hui Qi
Pages: 115-125
Published online on: 07 May 2020

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Article Open Access

VL30 retrotransposition is associated with induced EMT, CSC generation and tumorigenesis in HC11 mouse mammary stem‑like epithelial cells

Soteroula Thrasyvoulou, Georgios Vartholomatos, Georgios Markopoulos, Dimitrios Noutsopoulos, Stefania Mantziou, Foteini Gkartziou, Panagiotis Papageorgis, Antonia Charchanti, Panos Kouklis, Andreas I. Constantinou, Theodore Tzavaras
Pages: 126-138
Published online on: 28 April 2020

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Article Open Access

miR‑193b exhibits mutual interaction with MYC, and suppresses growth and metastasis of osteosarcoma

Jinjian Gao, Sai Ma, Fan Yang, Xu Chen, Wei Wang, Jianping Zhang, Yufang Li, Tao Wang, Lequn Shan
Pages: 139-155
Published online on: 29 April 2020

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Article Open Access

An elongated tract of polyQ in the carboxyl‑terminus of human α1A calcium channel induces cell apoptosis by nuclear translocation

Ji Sun, Xiguang Sun, Zhuo Li, Dihui Ma, Yudan Lv
Pages: 156-164
Published online on: 22 April 2020

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Article Open Access

Long non‑coding RNA H19 is involved in sorafenib resistance in hepatocellular carcinoma by upregulating miR‑675

Yongzi Xu, Yanhui Liu, Zhenrong Li, Hao Li, Xiqing Li, Lei Yan, Jiayan Mao, Jian Shen, Wei Chen, Fei Xue
Pages: 165-173
Published online on: 08 May 2020

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Article Open Access

Spred2 inhibits epithelial‑mesenchymal transition of colorectal cancer cells by impairing ERK signaling

Hao Wang, Shuchen Liu, Fanxuan Kong, Fengjun Xiao, Yuxiang Li, Hua Wang, Shun Zhang, Dandan Huang, Lisheng Wang, Yuefeng Yang
Pages: 174-184
Published online on: 16 April 2020

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Article Open Access

The miR‑625‑3p/AXL axis induces non‑T790M acquired resistance to EGFR‑TKI via activation of the TGF‑β/Smad pathway and EMT in EGFR‑mutant non‑small cell lung cancer

Wenwen Du, Lin Sun, Ting Liu, Jianjie Zhu, Yuanyuan Zeng, Yang Zhang, Xueting Wang, Zeyi Liu, Jian‑An Huang
Pages: 185-195
Published online on: 08 April 2020

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Article Open Access

Morpho‑functional study of the hypothalamic proline‑rich polypeptide apoptotic activity against mouse Ehrlich ascites carcinoma

S. Abrahamyan, I. Sahakyan, N. Tumasyan, N. Kocharyan, A. Simonyan, R. Aroutiounian, G. Chailyan, S. Chailyan, T. Davtyan, K. Galoian
Pages: 196-212
Published online on: 04 May 2020

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Article Open Access

RAD18 promotes colorectal cancer metastasis by activating the epithelial‑mesenchymal transition pathway

Peng Li, Chao He, Aidi Gao, Xueqi Yan, Xiaochun Xia, Jundong Zhou, Jinchang Wu
Pages: 213-223
Published online on: 21 April 2020

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Article Open Access

Exploration of the personalized immune checkpoint atlas of plasma cell dyscrasias patients using high‑dimensional single‑cell analysis

Chenggong Tu, Yongjiang Zheng, Hui Zhang, Jinheng Wang
Pages: 224-240
Published online on: 21 April 2020

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Article Open Access

1‑Palmitoyl‑2‑linoleoyl‑3‑acetyl‑rac‑glycerol ameliorates EGF‑induced MMP‑9 expression by promoting receptor desensitization in MDA‑MB‑231 cells

Kwang Hoon Yang, Guen Tae Kim, Solji Choi, Sun Young Yoon, Jae Wha Kim
Pages: 241-251
Published online on: 28 April 2020

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Article Open Access

High expression levels of polymeric immunoglobulin receptor are correlated with chemoresistance and poor prognosis in pancreatic cancer

Ryotaro Ohkuma, Erica Yada, Shumpei Ishikawa, Daisuke Komura, Yutaro Kubota, Kazuyuki Hamada, Atsushi Horiike, Tomoyuki Ishiguro, Yuya Hirasawa, Hirotsugu Ariizumi, Midori Shida, Makoto Watanabe, Rie Onoue, Kiyohiro Ando, Junji Tsurutani, Kiyoshi Yoshimura, Tetsuro Sasada, Takeshi Aoki, Masahiko Murakami, Tomoko Norose, Nobuyuki Ohike, Masafumi Takimoto, Shinichi Kobayashi, Takuya Tsunoda, Satoshi Wada
Pages: 252-262
Published online on: 11 May 2020

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Article

RET receptor expression and interaction with TRK receptors in neuroblastomas

Laura H. Tetri, Venkatadri Kolla, Rebecca L. Golden, Radhika Iyer, Jamie L. Croucher, Jee‑Hye Choi, Suzanne P. Macfarland, Koumudi Naraparaju, Peng Guan, Ferro Nguyen, Krutika S. Gaonkar, Pichai Raman, Garrett M. Brodeur
Pages: 263-272
Published online on: 15 April 2020

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Article

Novel SAHA‑bendamustine hybrid NL‑101 in combination with daunorubicin synergistically suppresses acute myeloid leukemia

Jingrui Jin, Xia Li, Wenjian Guo, Fenglin Li, Jiansong Huang, Xin Huang, Jiajia Pan, Shujuan Huang, Wenle Ye, Qing Ling, Jie Jin
Pages: 273-282
Published online on: 22 April 2020

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Article

Effect of the natural compound trans‑resveratrol on human MCM4 gene transcription

Fumiaki Uchiumi, Chihiro Katsuda, Motohiro Akui, Monami Kusaka, Marie Tanaka, Masashi Asai, Sei‑Ichi Tanuma
Pages: 283-292
Published online on: 28 April 2020

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Article

Role of glucose metabolism in the differential antileukemic effect of melatonin on wild‑type and FLT3‑ITD mutant cells

Noelia Puente‑Moncada, Maria Turos‑Cabal, Ana M. Sánchez‑Sánchez, Isaac Antolín, Federico Herrera, Jezabel Rodriguez‑Blanco, Cristina Duarte‑Olivenza, Carmen Rodriguez, Vanesa Martín
Pages: 293-302
Published online on: 15 April 2020

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Article

The effects of the Wnt/β‑catenin signaling pathway on apoptosis in HeLa cells induced by carbon ion irradiation

Jing Si, Jinhua Zhang, Lu Gan, Menghuan Guo, Yi Xie, Cuixia Di, Chao Sun, Fang Wang, Junfang Yan, Hong Zhang
Pages: 303-312
Published online on: 10 April 2020

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Article

Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway Corrigendum in /10.3892/or.2023.8593 Retraction in /10.3892/or.2026.9137

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Pages: 313-324
Published online on: 28 April 2020

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Article

Fluctuating role of antimicrobial peptide hCAP18/LL‑37 in oral tongue dysplasia and carcinoma

Marlene Vierthaler, Priscila Campioni Rodrigues, Elias Sundquist, Maria Siponen, Tuula Salo, Maija Risteli
Pages: 325-338
Published online on: 11 May 2020

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Article

Antihypertensive drug telmisartan suppresses the proliferation of gastric cancer cells in vitro and in vivo

Naoki Fujita, Koji Fujita, Hisakazu Iwama, Hideki Kobara, Shintaro Fujihara, Taiga Chiyo, Daisuke Namima, Hiroki Yamana, Toshiaki Kono, Kei Takuma, Masahiro Hirata, Kiyoyuki Kobayashi, Kiyohito Kato, Hideki Kamada, Asahiro Morishita, Kunihiko Tsutsui, Takashi Himoto, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki
Pages: 339-348
Published online on: 07 May 2020

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Article

Long non‑coding RNA GHET1 promotes osteosarcoma development and progression via Wnt/β‑catenin signaling pathway

Xingli Chen, Wei Zhao, Weimin Fan
Pages: 349-359
Published online on: 16 April 2020

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Article

Icariside II overcomes BRAF inhibitor resistance in melanoma by inducing ROS production and inhibiting MITF

Xiao Liu, Zheng Li, Ming Li, Jingxiu Chai, Shan He, Jinfeng Wu, Jinhua Xu
Pages: 360-370
Published online on: 15 April 2020

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Article

Metformin inhibits TGF‑β1‑induced epithelial‑mesenchymal transition and liver metastasis of pancreatic cancer cells

Juichiro Yoshida, Takeshi Ishikawa, Yuki Endo, Shinya Matsumura, Takayuki Ota, Katsura Mizushima, Yasuko Hirai, Kaname Oka, Tetsuya Okayama, Naoyuki Sakamoto, Ken Inoue, Kazuhiro Kamada, Kazuhiko Uchiyama, Tomohisa Takagi, Yuji Naito, Yoshito Itoh
Pages: 371-381
Published online on: 23 April 2020

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Article

Curcumin inhibits pancreatic cancer cell invasion and EMT by interfering with tumor‑stromal crosstalk under hypoxic conditions via the IL‑6/ERK/NF‑κB axis

Wei Li, Liankang Sun, Jianjun Lei, Zheng Wu, Qingyong Ma, Zheng Wang
Pages: 382-392
Published online on: 28 April 2020

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Article

Proline‑rich polypeptide‑1 decreases cancer stem cell population by targeting BAFF chromatin‑remodeling complexes in human chondrosarcoma JJ012 cells

Alexandra Moran, Aaron Hoyt, Anil Sedani, Caroline Granger, Shannon Saigh, Marzenna Blonska, Liu Zhao‑Ju, Sheila Ann Conway, Juan Pretell, Jeffrey Brown, Karina Galoian
Pages: 393-403
Published online on: 14 May 2020

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Journal Cover
July-2026 Volume 56 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Advances in Kruppel‑like factor 5 as a transcription factor and its role in gynecological tumors (Review)

Shuqi Zhang, Ping Li, Lixia Zhu
Article Number: 139
Published online on: 28 May 2026

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Review Open Access

Ferroptosis in colorectal cancer: Molecular mechanisms and regulatory crosstalk with therapeutic prospects (Review)

Mingxing Wu, Mingrong Zhang
Article Number: 138
Published online on: 27 May 2026

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Correction Open Access

[Corrigendum] 17‑AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA‑MB‑231 breast cancer cells

Yu Zuo, Heng Xu, Zhifeng Chen, Fengmin Xiong, Bei Zhang, Kaixian Chen, Hualiang Jiang, Cheng Luo, Hao Zhang
Article Number: 137
Published online on: 27 May 2026

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Review Open Access

Targeting lung cancer with tanshinones: Current mechanistic evidence and emerging opportunities (Review)

Zhengqi Guo, Xiaoci Li, Pengyu Suo, Zhanyu Lin, Ruixin Liu, Chenyu Chi
Article Number: 136
Published online on: 26 May 2026

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Review Open Access

Immune network remodeling driven by ferroptosis: Bidirectional interaction mechanisms among multiple immune cells in the lung cancer immune microenvironment (Review)

Fei Qu, Jiale Tong, Weiwei Qian, Qian He
Article Number: 135
Published online on: 26 May 2026

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Correction Open Access

[Corrigendum] Rapamycin enhances the sensitivity of ER‑positive breast cancer cells to tamoxifen by upregulating p73 expression

Lei Zhu, Xiao-Xia Li, Liang Shi, Jing Wu, Jia-Yi Qian, Tian-Song Xia, Wen-Bin Zhou, Xi Sun, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Article Number: 134
Published online on: 20 May 2026

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Review Open Access

Dual roles of lactylation modification in gastric cancer: Crosstalk between metabolic reprogramming and epigenetic regulation (Review)

Yuanbo Xu, Weili Wang, Yating Zhang, Yinqiu Fan, Wanying Dong, Jun Yang
Article Number: 133
Published online on: 20 May 2026

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Retraction Open Access

[Retracted] Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Article Number: 132
Published online on: 18 May 2026

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Article Open Access

Combination of ivermectin and metformin promotes autophagy in MCF‑7 cells by inhibiting phosphorylation of the PI3K/AKT/mTOR pathway

Huili Feng, Lixin He, Talha Umar, Haipeng Wang, Yanling Gao, Gongyi Chen, Panfeng Sun, Ling Yin, Wenbin Zhao, Huifang Lu, Ganzhen Deng, Changwei Qiu
Article Number: 131
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] ENO2 affects the EMT process of renal cell carcinoma and participates in the regulation of the immune micro­environment

Wei-Jie Chen, Wei Yang, Min Gong, Yi He, Da Xu, Jia-Xin Chen, Wen-Jin Chen, Wen-Yan Li, Yu-Qi Wang, Ke-Qin Dong, Xu Song, Xiu-Wu Pan, Xin-Gang Cui
Article Number: 130
Published online on: 13 May 2026

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Article Open Access

SRRT promotes prostate cancer progression and serves as a prognostic biomarker through STAT3 pathway activation

Lingxiang Lu, Ke Wu, Zhenfan Wang, Ruoxi Yang, Kai Li, Shuai Guo, Fei Wang, Zheng Ma
Article Number: 129
Published online on: 13 May 2026

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Retraction Open Access

[Retracted] Hsp72 controls bortezomib‑induced HepG2 cell death via interaction with pro‑apoptotic factors 

Giuseppe Calvaruso, Michela Giuliano, Patrizia Portanova, Ornella Pellerito, Renza Vento, Giovanni Tesoriere
Article Number: 128
Published online on: 11 May 2026

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Article Open Access

Effect of the miR‑26a/b‑5p‑STAT3‑YKL‑40 regulatory axis on proliferation, migration, and invasion of endometrial cancer cells

Xinzhao Sun, Shanshan Lin, Xueyan Zhong, Yanlu Luo, Jiahuang Yang, Jiangtao Fan
Article Number: 127
Published online on: 08 May 2026

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Review Open Access

Cancer signaling networks in tumor progression and drug resistance: Crosstalk, adaptive reprogramming and therapeutic targeting (Review)

Hongyan Li, Shiyuan Song, Linlin Wang, Qiang Liu
Article Number: 126
Published online on: 08 May 2026

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Article Open Access

A novel regulatory role of microRNA‑5590‑3p in hepatocellular carcinoma via the HOXB2/MYC axis

Bin Li, Lin Zhou
Article Number: 125
Published online on: 07 May 2026

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Retraction Open Access

[Retracted] SHIP1 is targeted by miR‑155 in acute myeloid leukemia

Hua Xue, Luo-Ming Hua, Ming Guo, Jian-Min Luo
Article Number: 124
Published online on: 05 May 2026

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Review Open Access

Chronic stress and cancer progression through neuro‑endocrine‑immune networks (Review)

Zhangxiang Zhu, Xiaohu Zhang, Jing Yan, Mingquan Wang, Yang Lv, Wuqiong Zhang, Hui Guo, Aimei Zheng
Article Number: 123
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] PTEN enhances G2/M arrest in etoposide‑treated MCF‑7 cells through activation of the ATM pathway

Ruopeng Zhang, Li Zhu, Lirong Zhang, Anli Xu, Zhengwei Li, Yijuan Xu, Pei He, Maoqing Wu, Fengxiang Wei, Chenhong Wang
Article Number: 122
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 56 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 7.7

CiteScore Rank: Q1: #76/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

A fibroblast activation protein degrader enhances cisplatin sensitivity in non‑small cell lung cancer

Yong Zhou, Ranhua Li, Xiaobo Chen, Cheng Zhang, Yanan Bao, Yue Cui, Xinghe Tong, Ting Xia, Xudong Yang, Jiqing Yang, Xiaochuan Yin
Article Number: 145
Published online on: 10 June 2026

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Review Open Access

Sterol regulatory element‑binding proteins: Master regulators of lipid metabolic reprogramming in cancer and emerging therapeutic targets (Review)

Qing Liu, Rui Wang, Zhenbo Li, Yihan Liu, Lei Wu, Yuqin Zhao, Jing Yang
Article Number: 144
Published online on: 04 June 2026

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Review Open Access

Dual targeting of mitochondrial metabolism and Rho GTPase signaling to suppress cancer metastasis (Review)

Angelina Daher, Zahraa Assi, Amjad Kanaan, Ahmad Al Khatib, Mirvat El Sibai
Article Number: 143
Published online on: 03 June 2026

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Review Open Access

Targeting colorectal cancer and T‑cell metabolism for the treatment of colorectal cancer (Review)

Qiangzong Yu, Pengbo Luan, Jingru Liang, Lixin Wang
Article Number: 142
Published online on: 02 June 2026

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Expression of Concern Open Access

[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells

Wangdi Liao, Guohua Li, Yu You, Hongping Wan, Qiong Wu, Chongwen Wang, Nonghua Lv
Article Number: 141
Published online on: 02 June 2026

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Article Open Access

Acylglycerol kinase contributes to cell proliferation by activating NF‑κB signaling pathway in pancreatic cancer

Kunkun Han, Qianyun Zhang, Shengnan Gao, Jigang Zhang, Xiao Mei, Fei Li, Xin Xu, Shu Li, Guodong Chen
Article Number: 140
Published online on: 29 May 2026

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