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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July-2020 Volume 44 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review

Molecularly targeted therapy and immunotherapy for hormone receptor‑positive/human epidermal growth factor receptor 2‑negative advanced breast cancer (Review)

Yuhua Song, Lin He, Yaling Wang, Qian Wu, Wenzhi Huang
Pages: 3-13
Published online on: 21 April 2020

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Article Open Access

HDGF enhances VEGF‑dependent angiogenesis and FGF‑2 is a VEGF‑independent angiogenic factor in non‑small cell lung cancer

Ryoji Eguchi, Ichiro Wakabayashi
Pages: 14-28
Published online on: 09 April 2020

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Article Open Access

Upregulated expression of MMP family genes is associated with poor survival in patients with esophageal squamous cell carcinoma via regulation of proliferation and epithelial‑mesenchymal transition

Guifeng Xu, Ling Ou, Ying Liu, Xiao Wang, Kaisheng Liu, Jieling Li, Junjun Li, Shaoqi Wang, Dane Huang, Kai Zheng, Shaoxiang Wang
Pages: 29-42
Published online on: 07 May 2020

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Article Open Access

TIRC7 inhibits Th1 cells by upregulating the expression of CTLA‑4 and STAT3 in mice with acute graft‑versus‑host disease

Feng Zhu, Tingting Qiu, Shengyun Zhu, Kai Zhao, Chong Chen, Jianlin Qiao, Bin Pan, Zhiling Yan, Wei Chen, Qiong Liu, Qingyun Wu, Jiang Cao, Wei Sang, Lingyu Zeng, Haiying Sun, Zhenyu Li, Kailin Xu
Pages: 43-54
Published online on: 21 April 2020

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Article Open Access

Increased expression of RBMS3 predicts a favorable prognosis in human gallbladder carcinoma

Youliang Wu, Delong Meng, Yexiang You, Ruochuan Sun, Qiang Yan, Junjun Bao, Yanjun Sun, Dapeng Yun, Yongxiang Li, Dengqun Sun
Pages: 55-68
Published online on: 23 April 2020

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Article Open Access

Kindlin‑2 suppresses cervical cancer cell migration through AKT/mTOR‑mediated autophagy induction

Guangteng Wu, Ying Long, Yan Lu, Yiming Feng, Xinmei Yang, Xun Xu, Desheng Yao
Pages: 69-76
Published online on: 04 May 2020

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Article Open Access

DJ‑1 is a new prognostic marker and predicts chemotherapy efficacy in colorectal cancer

Weimin Wang, Haibo Wang, Liangliang Xiang, Tengyang Ni, Feng Jin, Jianliang Deng, Yunlei Zhang, Ishikawa Shintaro, Yan Zhou, Yanqing Liu
Pages: 77-90
Published online on: 23 April 2020

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Article Open Access

Ciprofloxacin promotes polarization of CD86+CD206‑ macrophages to suppress liver cancer

Mengtian Fan, Sicheng Chen, Yaguang Weng, Xian Li, Yingjiu Jiang, Xiaowen Wang, Mengjun Bie, Liqin An, Menghao Zhang, Bin Chen, Gaigai Huang, Jinghong Wu, Mengying Zhu, Qiong Shi
Pages: 91-102
Published online on: 29 April 2020

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Article Open Access

Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway

Xianke Yan, Chao Yang, Wei Hu, Tao Chen, Qi Wang, Feng Pan, Bing Qiu, Bensen Tang
Pages: 103-114
Published online on: 12 May 2020

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Article Open Access

NEAT1 knockdown suppresses endothelial cell proliferation and induces apoptosis by regulating miR‑638/AKT/mTOR signaling in atherosclerosis

Xia Zhang, Ming‑Xiu Guan, Qiu‑Hong Jiang, Sai Li, Hong‑Yu Zhang, Zhi‑Guo Wu, Hong‑Liang Cong, Xiu‑Hui Qi
Pages: 115-125
Published online on: 07 May 2020

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Article Open Access

VL30 retrotransposition is associated with induced EMT, CSC generation and tumorigenesis in HC11 mouse mammary stem‑like epithelial cells

Soteroula Thrasyvoulou, Georgios Vartholomatos, Georgios Markopoulos, Dimitrios Noutsopoulos, Stefania Mantziou, Foteini Gkartziou, Panagiotis Papageorgis, Antonia Charchanti, Panos Kouklis, Andreas I. Constantinou, Theodore Tzavaras
Pages: 126-138
Published online on: 28 April 2020

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Article Open Access

miR‑193b exhibits mutual interaction with MYC, and suppresses growth and metastasis of osteosarcoma

Jinjian Gao, Sai Ma, Fan Yang, Xu Chen, Wei Wang, Jianping Zhang, Yufang Li, Tao Wang, Lequn Shan
Pages: 139-155
Published online on: 29 April 2020

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Article Open Access

An elongated tract of polyQ in the carboxyl‑terminus of human α1A calcium channel induces cell apoptosis by nuclear translocation

Ji Sun, Xiguang Sun, Zhuo Li, Dihui Ma, Yudan Lv
Pages: 156-164
Published online on: 22 April 2020

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Article Open Access

Long non‑coding RNA H19 is involved in sorafenib resistance in hepatocellular carcinoma by upregulating miR‑675

Yongzi Xu, Yanhui Liu, Zhenrong Li, Hao Li, Xiqing Li, Lei Yan, Jiayan Mao, Jian Shen, Wei Chen, Fei Xue
Pages: 165-173
Published online on: 08 May 2020

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Article Open Access

Spred2 inhibits epithelial‑mesenchymal transition of colorectal cancer cells by impairing ERK signaling

Hao Wang, Shuchen Liu, Fanxuan Kong, Fengjun Xiao, Yuxiang Li, Hua Wang, Shun Zhang, Dandan Huang, Lisheng Wang, Yuefeng Yang
Pages: 174-184
Published online on: 16 April 2020

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Article Open Access

The miR‑625‑3p/AXL axis induces non‑T790M acquired resistance to EGFR‑TKI via activation of the TGF‑β/Smad pathway and EMT in EGFR‑mutant non‑small cell lung cancer

Wenwen Du, Lin Sun, Ting Liu, Jianjie Zhu, Yuanyuan Zeng, Yang Zhang, Xueting Wang, Zeyi Liu, Jian‑An Huang
Pages: 185-195
Published online on: 08 April 2020

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Article Open Access

Morpho‑functional study of the hypothalamic proline‑rich polypeptide apoptotic activity against mouse Ehrlich ascites carcinoma

S. Abrahamyan, I. Sahakyan, N. Tumasyan, N. Kocharyan, A. Simonyan, R. Aroutiounian, G. Chailyan, S. Chailyan, T. Davtyan, K. Galoian
Pages: 196-212
Published online on: 04 May 2020

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Article Open Access

RAD18 promotes colorectal cancer metastasis by activating the epithelial‑mesenchymal transition pathway

Peng Li, Chao He, Aidi Gao, Xueqi Yan, Xiaochun Xia, Jundong Zhou, Jinchang Wu
Pages: 213-223
Published online on: 21 April 2020

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Article Open Access

Exploration of the personalized immune checkpoint atlas of plasma cell dyscrasias patients using high‑dimensional single‑cell analysis

Chenggong Tu, Yongjiang Zheng, Hui Zhang, Jinheng Wang
Pages: 224-240
Published online on: 21 April 2020

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Article Open Access

1‑Palmitoyl‑2‑linoleoyl‑3‑acetyl‑rac‑glycerol ameliorates EGF‑induced MMP‑9 expression by promoting receptor desensitization in MDA‑MB‑231 cells

Kwang Hoon Yang, Guen Tae Kim, Solji Choi, Sun Young Yoon, Jae Wha Kim
Pages: 241-251
Published online on: 28 April 2020

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Article Open Access

High expression levels of polymeric immunoglobulin receptor are correlated with chemoresistance and poor prognosis in pancreatic cancer

Ryotaro Ohkuma, Erica Yada, Shumpei Ishikawa, Daisuke Komura, Yutaro Kubota, Kazuyuki Hamada, Atsushi Horiike, Tomoyuki Ishiguro, Yuya Hirasawa, Hirotsugu Ariizumi, Midori Shida, Makoto Watanabe, Rie Onoue, Kiyohiro Ando, Junji Tsurutani, Kiyoshi Yoshimura, Tetsuro Sasada, Takeshi Aoki, Masahiko Murakami, Tomoko Norose, Nobuyuki Ohike, Masafumi Takimoto, Shinichi Kobayashi, Takuya Tsunoda, Satoshi Wada
Pages: 252-262
Published online on: 11 May 2020

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Article

RET receptor expression and interaction with TRK receptors in neuroblastomas

Laura H. Tetri, Venkatadri Kolla, Rebecca L. Golden, Radhika Iyer, Jamie L. Croucher, Jee‑Hye Choi, Suzanne P. Macfarland, Koumudi Naraparaju, Peng Guan, Ferro Nguyen, Krutika S. Gaonkar, Pichai Raman, Garrett M. Brodeur
Pages: 263-272
Published online on: 15 April 2020

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Article

Novel SAHA‑bendamustine hybrid NL‑101 in combination with daunorubicin synergistically suppresses acute myeloid leukemia

Jingrui Jin, Xia Li, Wenjian Guo, Fenglin Li, Jiansong Huang, Xin Huang, Jiajia Pan, Shujuan Huang, Wenle Ye, Qing Ling, Jie Jin
Pages: 273-282
Published online on: 22 April 2020

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Article

Effect of the natural compound trans‑resveratrol on human MCM4 gene transcription

Fumiaki Uchiumi, Chihiro Katsuda, Motohiro Akui, Monami Kusaka, Marie Tanaka, Masashi Asai, Sei‑Ichi Tanuma
Pages: 283-292
Published online on: 28 April 2020

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Article

Role of glucose metabolism in the differential antileukemic effect of melatonin on wild‑type and FLT3‑ITD mutant cells

Noelia Puente‑Moncada, Maria Turos‑Cabal, Ana M. Sánchez‑Sánchez, Isaac Antolín, Federico Herrera, Jezabel Rodriguez‑Blanco, Cristina Duarte‑Olivenza, Carmen Rodriguez, Vanesa Martín
Pages: 293-302
Published online on: 15 April 2020

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Article

The effects of the Wnt/β‑catenin signaling pathway on apoptosis in HeLa cells induced by carbon ion irradiation

Jing Si, Jinhua Zhang, Lu Gan, Menghuan Guo, Yi Xie, Cuixia Di, Chao Sun, Fang Wang, Junfang Yan, Hong Zhang
Pages: 303-312
Published online on: 10 April 2020

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Article

Hsp90 inhibitor 17‑AAG inhibits stem cell‑like properties and chemoresistance in osteosarcoma cells via the Hedgehog signaling pathway Corrigendum in /10.3892/or.2023.8593

Xiong Shu, Huiqi Liu, Rui Zhen, Yongsheng Jie, Lei Chen, Hui Qi, Chao Wang, Renxian Wang, Dafu Chen, Yuliang Ran
Pages: 313-324
Published online on: 28 April 2020

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Article

Fluctuating role of antimicrobial peptide hCAP18/LL‑37 in oral tongue dysplasia and carcinoma

Marlene Vierthaler, Priscila Campioni Rodrigues, Elias Sundquist, Maria Siponen, Tuula Salo, Maija Risteli
Pages: 325-338
Published online on: 11 May 2020

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Article

Antihypertensive drug telmisartan suppresses the proliferation of gastric cancer cells in vitro and in vivo

Naoki Fujita, Koji Fujita, Hisakazu Iwama, Hideki Kobara, Shintaro Fujihara, Taiga Chiyo, Daisuke Namima, Hiroki Yamana, Toshiaki Kono, Kei Takuma, Masahiro Hirata, Kiyoyuki Kobayashi, Kiyohito Kato, Hideki Kamada, Asahiro Morishita, Kunihiko Tsutsui, Takashi Himoto, Keiichi Okano, Yasuyuki Suzuki, Tsutomu Masaki
Pages: 339-348
Published online on: 07 May 2020

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Article

Long non‑coding RNA GHET1 promotes osteosarcoma development and progression via Wnt/β‑catenin signaling pathway

Xingli Chen, Wei Zhao, Weimin Fan
Pages: 349-359
Published online on: 16 April 2020

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Article

Icariside II overcomes BRAF inhibitor resistance in melanoma by inducing ROS production and inhibiting MITF

Xiao Liu, Zheng Li, Ming Li, Jingxiu Chai, Shan He, Jinfeng Wu, Jinhua Xu
Pages: 360-370
Published online on: 15 April 2020

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Article

Metformin inhibits TGF‑β1‑induced epithelial‑mesenchymal transition and liver metastasis of pancreatic cancer cells

Juichiro Yoshida, Takeshi Ishikawa, Yuki Endo, Shinya Matsumura, Takayuki Ota, Katsura Mizushima, Yasuko Hirai, Kaname Oka, Tetsuya Okayama, Naoyuki Sakamoto, Ken Inoue, Kazuhiro Kamada, Kazuhiko Uchiyama, Tomohisa Takagi, Yuji Naito, Yoshito Itoh
Pages: 371-381
Published online on: 23 April 2020

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Article

Curcumin inhibits pancreatic cancer cell invasion and EMT by interfering with tumor‑stromal crosstalk under hypoxic conditions via the IL‑6/ERK/NF‑κB axis

Wei Li, Liankang Sun, Jianjun Lei, Zheng Wu, Qingyong Ma, Zheng Wang
Pages: 382-392
Published online on: 28 April 2020

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Article

Proline‑rich polypeptide‑1 decreases cancer stem cell population by targeting BAFF chromatin‑remodeling complexes in human chondrosarcoma JJ012 cells

Alexandra Moran, Aaron Hoyt, Anil Sedani, Caroline Granger, Shannon Saigh, Marzenna Blonska, Liu Zhao‑Ju, Sheila Ann Conway, Juan Pretell, Jeffrey Brown, Karina Galoian
Pages: 393-403
Published online on: 14 May 2020

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 55 Issue 2

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Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Correction Open Access

[Corrigendum] Isolinderalactone enhances the inhibition of SOCS3 on STAT3 activity by decreasing miR‑30c in breast cancer

Meng-Chi Yen, Ying-Chu Shih, Ya-Ling Hsu, En-Shyh Lin, Yi-Shiuan Lin, Eing-Mei Tsai, Ya-Wen Ho, Ming-Feng Hou, Po-Lin Kuo
Article Number: 36
Published online on: 22 December 2025

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Hypoxia‑mediated Krebs von den Lungen‑6 expression in breast cancer: Implications for tumor invasion and metastasis

Taisei Ichihara, Yoshihiro Hayashi, Takuya Sato, Mitsuko Iguchi, Makoto Toi, Hironaga Satake, Ichiro Murakami
Article Number: 35
Published online on: 19 December 2025

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[Retracted] β‑elemene decreases cell invasion by upregulating E‑cadherin expression in MCF‑7 human breast cancer cells

Xian Zhang, Yang Zhang, Yinghua Li
Article Number: 34
Published online on: 18 December 2025

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Review Open Access

Research progress on the regulation of ferroptosis in NPC (Review)

Shuai Bai, Yanjie Guo, Jingling Qiang, Qiangfang Dai, Yanling Yang
Article Number: 33
Published online on: 18 December 2025

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[Retracted] Platelet‑derived growth factor BB mediates the glioma‑induced migration of bone marrow‑derived mesenchymal stem cells by promoting the expression of vascular cell adhesion molecule‑1 through the PI3K, P38 MAPK and NF‑κB pathways

Yi Hu, Peng Cheng, Jiang-Chun Ma, Yi-Xue Xue, Yun-Hui Liu
Article Number: 32
Published online on: 08 December 2025

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Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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