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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2014 Volume 45 Issue 5

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Breast cancer in European Union: An update of screening programmes as of March 2014 (Review)

E. Altobelli, A. Lattanzi
Pages: 1785-1792
Published online on: 01 September 2014

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Review

Targeting the PI3K/Akt pathway in prostate cancer: Challenges and opportunities (Review)

Paul Toren, Amina Zoubeidi
Pages: 1793-1801
Published online on: 14 August 2014

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Review

Pharmacological and dietary agents for colorectal cancer chemoprevention: Effects on polyamine metabolism (Review)

Michele Linsalata, Antonella Orlando, Francesco Russo
Pages: 1802-1812
Published online on: 14 August 2014

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Review

Radiation-induced signaling pathways that promote cancer cell survival (Review)

Ashley L. Hein, Michel M. Ouellette, Ying Yan
Pages: 1813-1819
Published online on: 20 August 2014

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Article

The role of APE/Ref-1 signaling pathway in hepatocellular carcinoma progression

Zhen Yang, Sun Yang, Bobbye J. Misner, Feng Liu-Smith, Frank L. Meyskens
Pages: 1820-1828
Published online on: 08 August 2014

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Article Open Access

Several fusion genes identified by whole transcriptome sequencing in a spindle cell sarcoma with rearrangements of chromosome arm 12q and MDM2 amplification

Ioannis Panagopoulos, Bodil Bjerkehagen, Ludmila Gorunova, Jeanne-Marie Berner, Kjetil Boye, Sverre Heim
Pages: 1829-1836
Published online on: 18 August 2014

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Article Open Access

Interferon-β inhibits glioma angiogenesis through downregulation of vascular endothelial growth factor and upregulation of interferon inducible protein 10

Shingo Takano, Eiichi Ishikawa, Masahide Matsuda, Tetsuya Yamamoto, Akira Matsumura
Pages: 1837-1846
Published online on: 25 August 2014

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Article Open Access

Large-scale expansion of γδ T cells and peptide-specific cytotoxic T cells using zoledronate for adoptive immunotherapy

Toshiaki Yoshikawa, Masashi Takahara, Mai Tomiyama, Mie Nieda, Ryuji Maekawa, Tetsuya Nakatsura
Pages: 1847-1856
Published online on: 03 September 2014

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Article Open Access

A stem cell medium containing neural stimulating factor induces a pancreatic cancer stem-like cell-enriched population

Yusaku Watanabe, Kiyoshi Yoshimura, Koichi Yoshikawa, Ryoichi Tsunedomi, Yoshitaro Shindo, Sou Matsukuma, Noriko Maeda, Shinsuke Kanekiyo, Nobuaki Suzuki, Atsuo Kuramasu, Kouhei Sonoda, Koji Tamada, Sei Kobayashi, Hideyuki Saya, Shoichi Hazama, Masaaki Oka
Pages: 1857-1866
Published online on: 14 August 2014

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Article

Significance of serine threonine tyrosine kinase 1 as a drug resistance factor and therapeutic predictor in acute leukemia

Shinya Nirasawa, Daisuke Kobayashi, Takashi Kondoh, Kageaki Kuribayashi, Maki Tanaka, Nozomi Yanagihara, Naoki Watanabe
Pages: 1867-1874
Published online on: 03 September 2014

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Article

Overexpression of integrin αv facilitates proliferation and invasion of oral squamous cell carcinoma cells via mek/erk signaling pathway that is activated by interaction of integrin αvβ8 with type Ⅰ collagen

Yasutaka Hayashido, Hisataka Kitano, Taishi Sakaue, Takahiko  Fujii, Mirei Suematsu, Shigeru Sakurai, Tetsuji Okamoto
Pages: 1875-1882
Published online on: 04 September 2014

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Article

Spatial localization of the JAG1/Notch1/osteopontin cascade modulates extrahepatic metastasis in hepatocellular carcinoma

Tong-Chun Xue, Jing-Huai Zou, Rong-Xin Chen, Jie-Feng Cui, Zhao-You Tang, Sheng-Long Ye
Pages: 1883-1890
Published online on: 29 August 2014

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Article

Codonolactone, a sesquiterpene lactone isolated from Chloranthus henryi Hemsl, inhibits breast cancer cell invasion, migration and metastasis by downregulating the transcriptional activity of Runx2

Wei Wang, Bin Chen, Ruolan Zou, Xiuying Tu, Songlin Tan, Hong Lu, Zhaojie Liu, Jianjiang Fu
Pages: 1891-1900
Published online on: 04 September 2014

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Article

Mitochondrial division inhibitor-1 induces mitochondrial hyperfusion and sensitizes human cancer cells to TRAIL-induced apoptosis

Mamoru Akita, Miki Suzuki-Karasaki, Kyoko Fujiwara, Chinatsu Nakagawa, Masayoshi Soma, Yukihiro Yoshida, Toyoko Ochiai, Yasuaki Tokuhashi, Yoshihiro Suzuki-Karasaki
Pages: 1901-1912
Published online on: 18 August 2014

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Article

Plumbagin reduces human colon cancer cell survival by inducing cell cycle arrest and mitochondria-mediated apoptosis

Binil Eldhose, Mia Gunawan, Mahbubur Rahman, Mukalel S. Latha, Vicente Notario
Pages: 1913-1920
Published online on: 08 August 2014

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Article

Relative expression of hMena11a and hMenaINV splice isoforms is a useful biomarker in development and progression of human breast carcinoma

Noriyuki Tanaka, Hiroshi Yoshida, Yoshio Suzuki, Kenichi Harigaya
Pages: 1921-1928
Published online on: 08 August 2014

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Article

Naringin inhibits growth and induces apoptosis by a mechanism dependent on reduced activation of NF‑κB/COX‑2‑caspase-1 pathway in HeLa cervical cancer cells

Lan Zeng, Yulan Zhen, Yiming Chen, Lin Zou, Ying Zhang, Fen Hu, Jianqiang Feng, Jianhua Shen, Bing Wei
Pages: 1929-1936
Published online on: 22 August 2014

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Article

Anisi stellati fructus extract attenuates the in vitro and in vivo metastatic and angiogenic potential of malignant cancer cells by downregulating proteolytic activity and pro-angiogenic factors

Aeyung Kim, Minju Im, Jin Yeul Ma
Pages: 1937-1948
Published online on: 18 August 2014

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Article

The pterocarpanquinone LQB-118 induces apoptosis in acute myeloid leukemia cells of distinct molecular subtypes and targets FoxO3a and FoxM1 transcription factors Corrigendum in /10.3892/ijo.2019.4874

Gabriela Nestal de Moraes, Carolina Pereira Castro, Eduardo Jesus Salustiano, Matheus Lourenço Dumas, Fernanda Costas, Eric Wing-Fai Lam, Paulo Roberto Ribeiro Costa, Raquel Ciuvalschi Maia
Pages: 1949-1958
Published online on: 21 August 2014

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Article Open Access

Exploring breast carcinogenesis through integrative genomics and epigenomics analyses

Chin Minning, Norfilza Mohd Mokhtar, Norlia Abdullah, Rohaizak Muhammad, Nor Aina Emran, Siti Aishah Md Ali, Roslan Harun, Rahman Jamal
Pages: 1959-1968
Published online on: 27 August 2014

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Article

Isoegomaketone induces apoptosis in SK-MEL-2 human melanoma cells through mitochondrial apoptotic pathway via activating the PI3K/Akt pathway

Soon-Jae Kwon, Ju-Hye Lee, Kwang-Deog Moon, Il-Yun Jeong, Sung-Tae Yee, Mi-Kyung Lee, Kwon-Il Seo
Pages: 1969-1976
Published online on: 14 August 2014

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Article

Transforming growth factor-β-induced miR‑143 expression in regulation of non-small cell lung cancer cell viability and invasion capacity in vitro and in vivo

Tianli Cheng, Chengping Hu, Huaping Yang, Liming Cao, Jian An
Pages: 1977-1988
Published online on: 27 August 2014

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Article

Neural stem cells preferentially migrate to glioma stem cells and reduce their stemness phenotypes

Suojun Zhang, Ruifan Xie, Tianyuan Zhao, Xiong Yang, lin Han, Fei Ye, Ting Lei, Feng Wan
Pages: 1989-1996
Published online on: 29 August 2014

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Article

Postnatal Notch1 activation induces T‑cell malignancy in conditional and inducible mouse models

Ju Liu, Fengyun Dong, Iris Fung, Edwin Chen, Thaddeus  D. Allen, Urban Deutsch, Corrinne G. Lobe
Pages: 1997-2004
Published online on: 29 August 2014

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Article

Clinical utility of PDSS2 expression to stratify patients at risk for recurrence of hepatocellular carcinoma

Mitsuro Kanda, Hiroyuki Sugimoto, Shuji Nomoto, Hisaharu Oya, Dai Shimizu, Hideki Takami, Ryoji Hashimoto, Fuminori Sonohara, Yukiyasu Okamura, Suguru Yamada, Tsutomu Fujii, Goro Nakayama, Masahiko Koike, Michitaka Fujiwara, Yasuhiro Kodera
Pages: 2005-2012
Published online on: 03 September 2014

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Article

MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells

Riccardo Di Fiore, Rosa Drago-Ferrante, Francesca Pentimalli, Domenico Di Marzo, Iris Maria Forte, Antonella D'Anneo, Daniela Carlisi, Anna De Blasio, Michela Giuliano, Giovanni Tesoriere, Antonio Giordano, Renza Vento
Pages: 2013-2023
Published online on: 22 August 2014

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Article

MicroRNA-135b promotes proliferation, invasion and migration of osteosarcoma cells by degrading myocardin

Wei-Guo Xu, Ying-Lie Shang, Xian-Rui Cong, Xia Bian, Zhen Yuan
Pages: 2024-2032
Published online on: 04 September 2014

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Article

E2F1 downregulation by arsenic trioxide in lung adenocarcinoma

Sze-Kwan Lam, Yuan-Yuan Li, Chun-Yan Zheng, Leanne Lee Leung, James Chung-Man Ho
Pages: 2033-2043
Published online on: 19 August 2014

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Article

Effects of D-allose in combination with docetaxel in human head and neck cancer cells

Kanako Indo, Hiroshi Hoshikawa, Kazuyo Kamitori, Fuminori Yamaguchi, Terusige Mori, Masaaki Tokuda, Nozomu Mori
Pages: 2044-2050
Published online on: 08 August 2014

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Article

Activated cytotoxic T-lymphocyte immunotherapy is effective for advanced oral and maxillofacial cancers

Tomoko Ohtani, Yoichi Yamada, Akifumi Furuhashi, Yukinobu Ohmura, Sayaka Nakamura, Hidefumi Kato, Kazuhiro Yoshikawa, Yoshiaki Kazaoka
Pages: 2051-2057
Published online on: 14 August 2014

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Article

Tie2-dependent deletion of α6 integrin subunit in mice reduces tumor growth and angiogenesis

Claire Bouvard, Zacharie Segaoula, Adèle De Arcangelis, Isabelle Galy-Fauroux, Laetitia Mauge, Anne-Marie Fischer, Elisabeth Georges-Labouesse, Dominique Helley
Pages: 2058-2064
Published online on: 01 September 2014

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Article

Sirt1 induction confers resistance to etoposide-induced genotoxic apoptosis in thyroid cancers

Ki Hwan Kweon, Cho Rok Lee, Soo Jung Jung, Eun Jeong Ban, Sang-Wook Kang, Jong Ju Jeong, Kee-Hyun Nam, Young Suk Jo, Jandee Lee, Woong Youn Chung
Pages: 2065-2075
Published online on: 08 August 2014

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Article

Emodin enhances ATRA-induced differentiation and induces apoptosis in acute myeloid leukemia cells

Yingyu Chen, Jing Li, Jianda Hu, Jing Zheng, Zhihong Zheng, Tingbo Liu, Zhenxing Lin, Minhui Lin
Pages: 2076-2084
Published online on: 19 August 2014

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Article

Identification of Hirsutine as an anti-metastatic phytochemical by targeting NF-κB activation

Chenghua Lou, Kei Takahashi, Tatsuro Irimura, Ikuo Saiki, Yoshihiro Hayakawa
Pages: 2085-2091
Published online on: 27 August 2014

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Article

Ciprofloxacin containing Mannich base and its copper complex induce antitumor activity via different mechanism of action

Yun Fu, Yingli Yang, Sufeng Zhou, Youxun Liu, Yanbin Yuan, Shaoshan Li, Changzheng Li
Pages: 2092-2100
Published online on: 19 August 2014

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Article

Epigenetic silencing of ARNTL, a circadian gene and potential tumor suppressor in ovarian cancer

Chia-Ming Yeh, Jacqueline Shay, Ting-Chuan Zeng, Jian-Liang Chou, Tim H.-M. Huang, Hung-Cheng Lai, Michael W.Y. Chan
Pages: 2101-2107
Published online on: 29 August 2014

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Article

Comparative secretome analysis of cholangiocarcinoma cell line in three-dimensional culture

Phanthakarn Tit-oon, Daranee Chokchaichamnankit, Amnart Khongmanee, Phannee Sawangareetrakul, Jisnuson Svasti, Chantragan Srisomsap
Pages: 2108-2116
Published online on: 03 September 2014

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Article

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion

Nathalie Khoury, Stephany El‑Hayek, Omayr Tarras, Marwan  El‑Sabban, Mirvat El‑Sibai, Sandra Rizk
Pages: 2117-2127
Published online on: 03 September 2014

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Article

Identification of a novel polyprenylated acylphloroglucinol‑derived SIRT1 inhibitor with cancer‑specific anti-proliferative and invasion-suppressing activities

lijia Zhu, Ji Qi, Christine Ya-Chi Chiao, Qiang Zhang, John A. Porco Jr, douglas V. Faller, Yan Dai
Pages: 2128-2136
Published online on: 03 September 2014

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Article

Non-pegylated liposome-encapsulated doxorubicin citrate plus cyclophosphamide or vinorelbine in metastatic breast cancer not previously treated with chemotherapy: A multicenter phase III study

V. Lorusso, F. Giotta, R. Bordonaro, E. Maiello, S. Del Prete, V. Gebbia, G. Filippelli, S. Pisconti, S. Cinieri, S. Romito, F. Riccardi, R. Forcignanò, M. Ciccarese, L. Petrucelli, V. Saracino, L. I. Lupo, A. Gambino, S. Leo
Pages: 2137-2142
Published online on: 18 August 2014

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Article

MicroRNA-449 suppresses proliferation of hepatoma cell lines through blockade lipid metabolic pathway related to SIRT1 Retraction in /10.3892/ijo.2023.5525

Hongyi Zhang, Zhiqiang Feng, Rui Huang, Zhenglin Xia, Guoan Xiang, Jinqian Zhang
Pages: 2143-2152
Published online on: 13 August 2014

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Article

In vitro modeling of HER2-targeting therapy in disseminated prostate cancer

Jennie Andersson, Maria Rosestedt, Veronika Asplund, Nazila Yavari, Anna Orlova
Pages: 2153-2158
Published online on: 29 August 2014

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Article

Effects of nutrients on matrix metalloproteinases in human T-lymphotropic virus type 1 positive and negative malignant T-lymphocytes Retraction in /10.3892/ijo.2022.5451

Steve Harakeh, Raefa Abou-Khouzam, Ghazi A. Damanhouri, Ahmed Al-Hejin, Taha Kumosani, Aleksandra Niedzwiecki, Mathias Rath, Elie Barbour, Mona Diab-Assaf, Rania Azar
Pages: 2159-2166
Published online on: 03 September 2014

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Article

Sorafenib and nilotinib resensitize tamoxifen resistant breast cancer cells to tamoxifen treatment via estrogen receptor α

Astrid M. Pedersen, Susan Thrane, Anne E. Lykkesfeldt, Christina W. Yde
Pages: 2167-2175
Published online on: 22 August 2014

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Journal Cover
September-2026 Volume 69 Issue 3

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

The role of deubiquitinating enzymes and their inhibitors in esophageal carcinoma (Review)

Yu Zhao, Chenghai He, Kexin Chen, Nanting Sun, Ruonan He, Guodong Li
Article Number: 108
Published online on: 16 July 2026

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Correction Open Access

[Corrigendum] AHIF promotes glioblastoma progression and radioresistance via exosomes

Xuejun Dai, Keman Liao, Zhijun Zhuang, Binghong Chen, Zhiyi Zhou, Sunhai Zhou, Guoshi Lin, Feifei Zhang, Yingying Lin, Yifeng Miao, Zhiqiang Li, Renhua Huang, Yongming Qiu, Ruisheng Lin
Article Number: 107
Published online on: 15 July 2026

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Article Open Access

Triptonide enhances DNA damage by inhibiting TRIP13‑mediated DNA repair and synergizes with bortezomib to suppress multiple myeloma

Fen He, Junjun Li, Lijun Peng, Hongyan Zhao, Maoyou Lu, Ruixin Gao, Siqi Wang, Yu Chen, Ruihan Tang, Zhengguo Li, Linlin Zhang, Xinyu Zhang, Qianhao Li, Weihui Chen, Jiayu Liu, Cong Luo, Xi Zeng, Jiliang Xia
Article Number: 106
Published online on: 14 July 2026

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Article Open Access

YAP1‑mediated cytoplasmic‑nuclear translocation of SREBP2 promotes colorectal cancer via regulation of cholesterol metabolism

Luhui Zhong, Min Sun, Di Wu, Yulan Zeng, Min Zhou, Rui Gong, Feifei Gu, Kai Zhang, Xiaoyan Hu, Yue Hu
Article Number: 105
Published online on: 13 July 2026

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Review Open Access

Immunoediting and precision biomarkers in prostate cancer: The emerging role of liquid biopsy, immune contexture and HLA genotype (Review)

Constantin N. Baxevanis, Savvas Stokidis, Sotirios P. Fortis, Maria Goulielmaki, Ourania E. Tsitsilonis, Angelos D. Gritzapis
Article Number: 104
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples

Giovanni Luca Gravina, Andrea Mancini, Guido Ranieri, Boris Di Pasquale, Francesco Marampon, Luigi Di Clemente, Enrico Ricevuto, Claudio Festuccia
Article Number: 103
Published online on: 13 July 2026

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Review Open Access

The neural stem cell‑NSCLC axis: Molecular drivers, microenvironment crosstalk and emerging therapies (Review)

Yanling Xu, Hanmei Duan, Peng Lu, Feng Liu
Article Number: 102
Published online on: 10 July 2026

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Review Open Access

TGF‑β1 in cancer: From tumour suppressor to promoter, molecular mechanisms, and precision therapeutic strategies (Review)

Chao Huang
Article Number: 101
Published online on: 10 July 2026

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Article Open Access

T‑box transcription factor 15 regulated by methyltransferase‑like 3‑mediated N6‑methyladenosine modification promotes immune escape and progression of gastric cancer by activating matrix metalloproteinase 14 transcription

Hongsai Hu, Rong He, Minji Liu, Xuli Liu, Qiongjia Ai, Min Chen, Qian Wang, Wenhui Chen, Weiming Qu
Article Number: 100
Published online on: 09 July 2026

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Review Open Access

Glycolysis‑driven immunosuppression in gastric cancer: Metabolic crosstalk between tumor cells and the immune microenvironment (Review)

Bo Zhang, Lihan Shang, Ziyu Kuang, Chaoran Wang, Bingsheng Sun, Fanming Kong
Article Number: 99
Published online on: 09 July 2026

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Review Open Access

New insights into the physiological, pathological and pharmacological roles of voltage‑gated potassium channel Kv10.1 in cancer (Review)

Yuxiao Zhen, Weibo Hu, Shanshan Dong, Bochang Wang, Jian Shen, Leyuan Ding, Lifeng Li, Hailong An, Xuzhao Wang, Yafei Chen
Article Number: 98
Published online on: 09 July 2026

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Retraction Open Access

[Retracted] Glycyrrhetinic acid induces G1‑phase cell cycle arrest in human non‑small cell lung cancer cells through endoplasmic reticulum stress pathway

Jie Zhu, Meijuan Chen, Ning Chen, Aizhen Ma, Chunyan Zhu, Ruolin Zhao, Miao Jiang, Jing Zhou, Lihong Ye, Haian Fu, Xu Zhang
Article Number: 97
Published online on: 06 July 2026

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October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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