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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2019 Volume 41 Issue 6

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Dietary baker's yeast sensitizes Ehrlich mammary adenocarcinoma to paclitaxel in mice bearing tumor

Mamdooh Ghoneum, Nariman K. Badr El-Din, Ashraf Z. Mahmoud, Lucilene Tolentino, Deyu Pan, Tahia Ali Hassan
Pages: 3155-3166
Published online on: 10 April 2019

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Article Open Access

Optimal subset of signature miRNAs consisting of 7 miRNAs that can serve as a novel diagnostic and prognostic predictor for the progression of cervical cancer

Can Shi, Yijun Yang, Lei Zhang, Ting Zhang, Juanpeng Yu, Shanshan Qin, Yingchun Gao
Pages: 3167-3178
Published online on: 03 April 2019

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Article Open Access

WYE-354 restores Adriamycin sensitivity in multidrug-resistant acute myeloid leukemia cell lines

Sara M. Ibrahim, Sherin Bakhashab, Asad M. Ilyas, Peter N. Pushparaj, Sajjad Karim, Jalaluddin A. Khan, Adel M. Abuzenadah, Adeel G. Chaudhary, Muhammed H. Al-Qahtani, Farid Ahmed
Pages: 3179-3188
Published online on: 02 April 2019

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Article Open Access

ARPC2 promotes breast cancer proliferation and metastasis

Zhongle Cheng, Wei Wei, Zhengshen Wu, Jing Wang, Xiaojuan Ding, Youjing Sheng, Yinli Han, Qiang Wu
Pages: 3189-3200
Published online on: 12 April 2019

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Article Open Access

Single‑cell intratumoral stemness analysis reveals the involvement of cell cycle and DNA damage repair in two different types of esophageal cancer

Hongjin Wu, Ying Li, Qiang Hou, Rongjin Zhou, Ziwei Li, Shixiu Wu, Juehua Yu, Mingfeng Jiang
Pages: 3201-3208
Published online on: 15 April 2019

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Article Open Access

Effects of ginsenoside Rg3 on epigenetic modification in ovarian cancer cells

Lingqin Zhao, Huafeng Shou, Lu Chen, Wen Gao, Chenyan Fang, Ping Zhang
Pages: 3209-3218
Published online on: 12 April 2019

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Article Open Access

JAK3/STAT3 oncogenic pathway and PRDM1 expression stratify clinicopathologic features of extranodal NK/T‑cell lymphoma, nasal type

Jumei Liu, Li Liang, Dong Li, Lin Nong, Yalin Zheng, Sixia Huang, Bo Zhang, Ting Li
Pages: 3219-3232
Published online on: 12 April 2019

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Article Open Access

A 19‑miRNA Support Vector Machine classifier and a 6‑miRNA risk score system designed for ovarian cancer patients Corrigendum in /10.3892/or.2019.7385

Jingwei Dong, Mingjun Xu
Pages: 3233-3243
Published online on: 10 April 2019

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Article Open Access

Gene profiling of HepG2 cells following nitidine chloride treatment: An investigation with microarray and Connectivity Mapping

Li‑Min Liu, Peng Lin, Hong Yang, Yi‑Wu Dang, Gang Chen
Pages: 3244-3256
Published online on: 02 April 2019

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Article Open Access

Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib Retraction in /10.3892/or.2025.8866

Zelong Yang, Jie Zhang, Xiaotong Lin, Di Wu, Guixi Li, Chunlian Zhong, Lei Fang, Peng Jiang, Liangyu Yin, Leida Zhang, Ping Bie, Chuan‑Ming Xie
Pages: 3257-3269
Published online on: 04 April 2019

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Article Open Access

LRG‑1 enhances the migration of thyroid carcinoma cells through promotion of the epithelial‑mesenchymal transition by activating MAPK/p38 signaling

Zhengfeng Ban, Jinnian He, Zhenzhen Tang, Linlin Zhang, Zhiwen Xu
Pages: 3270-3280
Published online on: 17 April 2019

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Article Open Access

Effects of LDOC1 on colorectal cancer cells via downregulation of the Wnt/β-catenin signaling pathway

Jiayi Jiang, You Li, Zheng Jiang
Pages: 3281-3291
Published online on: 17 April 2019

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Article Open Access

Deubiquitinase USP9X regulates the invasion of prostate cancer cells by regulating the ERK pathway and mitochondrial dynamics

Jinsong Zhang, Jiansong Wang, Ting Luan, Yigang Zuo, Jian Chen, Heng Zhang, Zhenni Ye, Haifeng Wang, Bing Hai
Pages: 3292-3304
Published online on: 18 April 2019

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Article

TRAIP regulates Histone H2B monoubiquitination in DNA damage response pathways

Ye Gi Han, Miyong Yun, Minji Choi, Seok‑Geun Lee, Hongtae Kim
Pages: 3305-3312
Published online on: 02 April 2019

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Article

Identification of dysregulated microRNAs associated with diagnosis and prognosis in triple‑negative breast cancer: An in silico study

Chunni Fan, Ning Liu
Pages: 3313-3324
Published online on: 02 April 2019

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Article

TRIM52 regulates the proliferation and invasiveness of lung cancer cells via the Wnt/β‑catenin pathway

Xiaoyan Mu, Hegen Li, Lei Zhou, Weijie Xu
Pages: 3325-3334
Published online on: 11 April 2019

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Article

Dynamic contrast enhanced‑magnetic resonance imaging for the early evaluation of the response to docetaxel in rats with epithelial ovarian cancer

Su‑Juan Yuan, Tian‑Kui Qiao, Jin‑Wei Qiang, Song‑Qi Cai
Pages: 3335-3346
Published online on: 17 April 2019

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Article

Upregulated histamine receptor H3 promotes tumor growth and metastasis in hepatocellular carcinoma

Deliang Yu, Jing Zhao, Yuhong Wang, Jing Hu, Qinchuan Zhao, Jibin Li, Jianjun Zhu
Pages: 3347-3354
Published online on: 16 April 2019

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Article

Isobavachalcone exerts anti‑proliferative and pro‑apoptotic effects on human liver cancer cells by targeting the ERKs/RSK2 signaling pathway

Binbin Li, Nansong Xu, Zheng Wan, Li Ma, Huahui Li, Weijie Cai, Xiumei Chen, Zunnan Huang, Zhiwei He
Pages: 3355-3366
Published online on: 02 April 2019

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Article

miR‑888 regulates cancer progression by targeting multiple targets in lung adenocarcinoma

Ji‑Xiang Cao
Pages: 3367-3376
Published online on: 16 April 2019

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Article

Prodigiosin isolated from Serratia marcescens in the Periplaneta americana gut and its apoptosis‑inducing activity in HeLa cells

Pei‑Bin Lin, Juan Shen, Pei‑Yu Ou, Ling‑Yan Liu, Zhi‑Yu Chen, Fu‑Jiang Chu, Jie Wang, Xiao‑Bao Jin
Pages: 3377-3385
Published online on: 02 April 2019

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Article

Overexpression of lncRNA TUSC7 reduces cell migration and invasion in colorectal cancer

Haixia Zhang, Yanli Song, Changqing Yang, Xianzheng Wu
Pages: 3386-3392
Published online on: 09 April 2019

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Article

1α,25‑Dihydroxyvitamin D3 restrains stem cell‑like properties of ovarian cancer cells by enhancing vitamin D receptor and suppressing CD44

Mintao Ji, Lizhi Liu, Yongfeng Hou, Bingyan Li
Pages: 3393-3403
Published online on: 15 April 2019

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Article

Synergistic effect of arsenic trioxide, vismodegib and temozolomide on glioblastoma

Costansia Bureta, Yoshinobu Saitoh, Hiroto Tokumoto, Hiromi Sasaki, Shingo Maeda, Satoshi Nagano, Setsuro Komiya, Noboru Taniguchi, Takao Setoguchi
Pages: 3404-3412
Published online on: 04 April 2019

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Article

TRPC5‑induced autophagy promotes the TMZ‑resistance of glioma cells via the CAMMKβ/AMPKα/mTOR pathway

Yan Zou, Mu Chen, Shuai Zhang, Zeng'li Miao, Jing Wang, Xiao'jie Lu, Xu'dong Zhao
Pages: 3413-3423
Published online on: 02 April 2019

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Article

Overexpression of calpain‑1 predicts poor outcome in patients with colorectal cancer and promotes tumor cell progression associated with downregulation of FLNA

Changzhao Xu, Xiaoxiao Yu, Yuesheng Zhu, Zhenzhai Cai, Lingmin Yu, Ying Lin, Hejie Yu, Zhanxiong Xue, Lingling Zhou
Pages: 3424-3434
Published online on: 16 April 2019

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Article

Upregulation of LGMNP1 confers radiotherapy resistance in glioblastoma

Hao Xu, Binghong Chen, Jin Xing, Zilong Wei, Chaobo Liu, Yongming Qiu, Yingying Lin, Li Ren
Pages: 3435-3443
Published online on: 18 April 2019

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Article

Effect of electrochemotherapy with betulinic acid or cisplatin on regulation of heat shock proteins in metastatic human carcinoma cells in vitro

Justyna Mączyńska, Anna Choromańska, Justyna Kutkowska, Małgorzata Kotulska, Maciej Zalewski, Jerzy Zalewski, Julita Kulbacka, Jolanta Saczko
Pages: 3444-3454
Published online on: 08 April 2019

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Article

Effect and changes in PD‑1 expression of CD19 CAR‑T cells from T cells highly expressing PD‑1 combined with reduced‑dose PD‑1 inhibitor

Rui Zhang, Qi Deng, Yan‑Yu Jiang, Hai‑Bo Zhu, Jia Wang, Ming‑Feng Zhao
Pages: 3455-3463
Published online on: 03 April 2019

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Article

Differential expression of tescalcin by modification of promoter methylation controls cell survival in gastric cancer cells

Tae Woo Kim, Seung Ro Han, Jong‑Tae Kim, Seung‑Min Yoo, Myung‑Shin Lee, Seung‑Hoon Lee, Yun Hee Kang, Hee Gu Lee
Pages: 3464-3474
Published online on: 04 April 2019

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Article

JS‑K induces G2/M phase cell cycle arrest and apoptosis in A549 and H460 cells via the p53/p21WAF1/CIP1 and p27KIP1 pathways

Zeqing Song, Yongxin Yin, Siyuan Hao, Jianmao Wei, Bin Liu, Xiaojie Huang, Chenfeng Gao, Runzhi Zhu, Weiguo Liao, De Cai
Pages: 3475-3487
Published online on: 09 April 2019

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Article

Methylation of the promoter region of the MTRR gene in childhood acute lymphoblastic leukemia

Jun Bai, Lijuan Li, Yi Li, Qunfei Chen, Liansheng Zhang, Xiaodong Xie
Pages: 3488-3498
Published online on: 12 April 2019

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Article

Heptadecanoic acid inhibits cell proliferation in PC‑9 non‑small‑cell lung cancer cells with acquired gefitinib resistance

Changzhi Xu, Pengfei Wu, Jiajia Gao, Lanlan Zhang, Tengfei Ma, Bingbing Ma, Shuai Yang, Guojian Shao, Yang Yu, Xunduan Huang, Xingyuan Yang, Buchang Zhang
Pages: 3499-3507
Published online on: 18 April 2019

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Article

Acquisition of gemcitabine resistance enhances angiogenesis via upregulation of IL‑8 production in pancreatic cancer

Hiroyuki Imafuji, Yoichi Matsuo, Goro Ueda, Kan Omi, Yuichi Hayashi, Kenta Saito, Ken Tsuboi, Mamoru Morimoto, Shuji Koide, Ryo Ogawa, Masayasu Hara, Hiroki Takahashi, Shuji Takiguchi
Pages: 3508-3516
Published online on: 09 April 2019

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Article

Resveratrol analogues surprisingly effective against triple‑negative breast cancer, independent of ERα

Xylia J. Horgan, Hannah Tatum, Emily Brannan, Daniel H. Paull, Lyndsay V. Rhodes
Pages: 3517-3526
Published online on: 16 April 2019

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Article

miR‑145‑5p is associated with pathological complete response to neoadjuvant chemotherapy and impairs cell proliferation by targeting TGFβR2 in breast cancer

Frederik García‑García, Yarely M. Salinas‑Vera, Raúl García‑Vázquez, Laurence A. Marchat, Sergio Rodríguez‑Cuevas, José Sullivan López‑González, Ángeles Carlos‑Reyes, Rosalío Ramos‑Payán, Maribel Aguilar‑Medina, Carlos Pérez‑Plasencia, Erika Ruíz‑García, César López‑Camarillo
Pages: 3527-3534
Published online on: 05 April 2019

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Article

DNA methylation of metallothionein genes is associated with the clinical features of renal cell carcinoma

Ruta Maleckaite, Algirdas Zalimas, Arnas Bakavicius, Feliksas Jankevicius, Sonata Jarmalaite, Kristina Daniunaite
Pages: 3535-3544
Published online on: 10 April 2019

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Article

Combination of SB431542, CHIR99021 and PD0325901 has a synergic effect on abrogating valproic acid‑induced epithelial‑mesenchymal transition and stemness in HeLa, 5637 and SCC‑15 cells

Yanmin Zhang, Yusen Zhang, Minghua Li, Fanhua Meng, Zhendong Yu, Yun Chen, Guanghui Cui
Pages: 3545-3554
Published online on: 01 April 2019

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Article

Cellular response to glutamine and/or glucose deprivation in in vitro transformed human fibroblasts

Ilaria Chiodi, Giulia Picco, Carolina Martino, Chiara Mondello
Pages: 3555-3564
Published online on: 17 April 2019

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Article

Propofol may increase caspase and MAPK pathways, and suppress the Akt pathway to induce apoptosis in MA‑10 mouse Leydig tumor cells

Fu‑Chi Kang, Shu‑Chun Wang, Edmund Cheung So, Ming‑Min Chang, Kar‑Lok Wong, Ka Shun Cheng, Yung‑Chia Chen, Bu‑Miin Huang
Pages: 3565-3574
Published online on: 18 April 2019

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Article

Long non‑coding RNA RP1‑163G9.1 is downregulated in gastric adenocarcinoma and is associated with a poor prognosis

Baochang Sun, Yuan Dang, Fan Zhang, Kewen Li, Xiaojuan Ouyang, Kai Wang, Qiaojia Huang
Pages: 3575-3585
Published online on: 17 April 2019

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Retraction Open Access

[Retracted] Serum‑free‑medium‑type mesenchymal stem cell culture supernatant exerts a protective effect on A549 lung epithelial cells in acute lung injury induced by H2O2

Jian Wu, An‑Quan Shang, Chu Chen, Wei‑Wei Wang, Cun‑Quan Xiong, Nai‑Zhou Guo
Pages: 3586-3586
Published online on: 29 March 2019

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Correction Open Access

[Corrigendum] Metformin suppresses hypoxia‑induced migration via the HIF‑1α/VEGF pathway in gallbladder cancer in vitro and in vivo

Jianwen Ye, Kunlun Chen, Lei Qi, Renfeng Li, Hongwei Tang, Chuang Zhou, Wenlong Zhai
Pages: 3587-3587
Published online on: 05 April 2019

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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