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Print ISSN: 1021-335X Online ISSN: 1791-2431
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
April-2020 Volume 43 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Article Open Access

Identification of KIF15 as a potential therapeutic target and prognostic factor for glioma

Qilong Wang, Bin Han, Wu Huang, Chunjian Qi, Fang Liu
Pages: 1035-1044
Published online on: 21 February 2020

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Article Open Access

Long non‑coding RNA CCAT1 enhances human non‑small cell lung cancer growth through downregulation of microRNA‑218

Lijiang Zhao, Limin Wang, Yongfeng Wang, Ping Ma
Pages: 1045-1052
Published online on: 12 February 2020

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Article Open Access

Catalpol‑mediated microRNA‑34a suppresses autophagy and malignancy by regulating SIRT1 in colorectal cancer

Peng‑Fei Qiao, Lei Yao, Zhao‑Lin Zeng
Pages: 1053-1066
Published online on: 07 February 2020

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Article Open Access

Sulforaphane suppresses carcinogenesis of colorectal cancer through the ERK/Nrf2‑UDP glucuronosyltransferase 1A metabolic axis activation

Qian Hao, Min Wang, Nuan‑Xin Sun, Cheng Zhu, Ying‑Min Lin, Cui Li, Fang Liu, Wen‑Wen Zhu
Pages: 1067-1080
Published online on: 10 February 2020

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Article Open Access

Reduced expression of exosomal miR‑29s in peritoneal fluid is a useful predictor of peritoneal recurrence after curative resection of gastric cancer with serosal involvement

Hideyuki Ohzawa, Akira Saito, Yuko Kumagai, Yuki Kimura, Hironori Yamaguchi, Yoshinori Hosoya, Alan Kawarai Lefor, Naohiro Sata, Joji Kitayama
Pages: 1081-1088
Published online on: 17 February 2020

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Article Open Access

Targeted deep sequencing contributes to guiding personalized targeted therapy for advanced biliary tract cancer patients with non‑radical resection: A real‑world study

Feiling Feng, Qingbao Cheng, Dadong Zhang, Bin Li, Hao Qin, Chang Xu, Miao Han, Yong Yu, Zhizhen Li, Jing‑Yu Li, Zhiquan Qiu, Lei Xiong, Chen Liu, Fugen Li, Bin Yi, Xiaoqing Jiang
Pages: 1089-1102
Published online on: 06 February 2020

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Article Open Access

Knockdown of MMP‑1 inhibits the progression of colorectal cancer by suppressing the PI3K/Akt/c‑myc signaling pathway and EMT

Kai Wang, Jianbao Zheng, Junhui Yu, Yunhua Wu, Jing Guo, Zhengshui Xu, Xuejun Sun
Pages: 1103-1112
Published online on: 06 February 2020

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Article Open Access

Activation of NLRP3 inflammasome promotes the proliferation and migration of esophageal squamous cell carcinoma

Shuang Yu, Jian‑Jian Yin, Jin‑Xin Miao, Shi‑Gang Li, Chen‑Zheng Huang, Ning Huang, Tian‑Li Fan, Xiang‑Nan Li, Yao‑He Wang, Sheng‑Na Han, Li‑Rong Zhang
Pages: 1113-1124
Published online on: 07 February 2020

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Article Open Access

Exosomes derived from Piwil2‑induced cancer stem cells transform fibroblasts into cancer‑associated fibroblasts Corrigendum in /10.3892/or.2022.8273

Dan Zhang, Dian Li, Lianju Shen, Dong Hu, Bo Tang, Wenhao Guo, Zhang Wang, Zhaoxia Zhang, Guanghui Wei, Dawei He
Pages: 1125-1132
Published online on: 10 February 2020

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Article Open Access

Integrated analysis of the E2F transcription factors across cancer types

Haiwei Wang, Xinrui Wang, Liangpu Xu, Ji Zhang, Hua Cao
Pages: 1133-1146
Published online on: 17 February 2020

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Article Open Access

Periostin induces epithelial‑to‑mesenchymal transition via the integrin α5β1/TWIST‑2 axis in cholangiocarcinoma

Jumaporn Sonongbua, Suchada Siritungyong, Suyanee Thongchot, Thanpawee Kamolhan, Kusumawadee Utispan, Peti Thuwajit, Ananya Pongpaibul, Sopit Wongkham, Chanitra Thuwajit
Pages: 1147-1158
Published online on: 31 January 2020

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Article Open Access

Tanshinone IIA reduces secretion of pro‑angiogenic factors and inhibits angiogenesis in human colorectal cancer

Lihong Zhou, Hua Sui, Ting Wang, Ru Jia, Zhaozhou Zhang, Jie Fu, Yuanyuan Feng, Ningning Liu, Qing Ji, Yan Wang, Bimeng Zhang, Qi Li, Yan Li
Pages: 1159-1168
Published online on: 12 February 2020

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Article Open Access

MicroRNA‑22 mediates the cisplatin resistance of osteosarcoma cells by inhibiting autophagy via the PI3K/Akt/mTOR pathway

Chen‑Yang Meng, Zhen‑Qun Zhao, Rui Bai, Wei Zhao, Yu‑Xing Wang, Hui‑Qin Xue, Liang Sun, Chao Sun, Wei Feng, Shi‑Bing Guo
Pages: 1169-1186
Published online on: 07 February 2020

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Article Open Access

Cutoff of 25% for Ki67 expression is a good classification tool for prognosis in colorectal cancer in the AJCC‑8 stratification

Guojun Tong, Guiyang Zhang, Jian Liu, Zhaozheng Zheng, Yan Chen, Pingping Niu, Xuting Xu
Pages: 1187-1198
Published online on: 21 February 2020

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Article Open Access

Epigenetic control of the EWS‑FLI1 promoter in Ewing's sarcoma

C.  Montoya, L. Rey, J. Rodríguez, M. J. Fernández, D.  Troncoso, A.  Cañas, O. Moreno, B. Henríquez, A. Rojas
Pages: 1199-1207
Published online on: 05 February 2020

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Article Open Access

Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer

Lu Bai, Jing Liang, Lihong Li, Enxiao Li
Pages: 1208-1220
Published online on: 12 February 2020

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Article Open Access

MicroRNA‑299‑5p inhibits cell metastasis in breast cancer by directly targeting serine/threonine kinase 39

Chenxing Li, Aiying Wang, Yanke Chen, Yan Liu, Hui Zhang, Jun Zhou
Pages: 1221-1233
Published online on: 31 January 2020

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Article Open Access

Comprehensive circular RNA expression profiling with associated ceRNA network reveals their therapeutic potential in cholesteatoma

Juanjuan Gao, Qi Tang, Ruoyan Xue, Xiaohui Zhu, Shihua Wang, Yongli Zhang, Wenbin Liu, Zhiqiang Gao, Hua Yang
Pages: 1234-1244
Published online on: 12 February 2020

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Article Open Access

Thapsigargin promotes colorectal cancer cell migration through upregulation of lncRNA MALAT1

Xia Jiang, Dongyun Li, Guiqi Wang, Jue Liu, Xingkai Su, Weifang Yu, Yuanyuan Wang, Congjie Zhai, Yuegeng Liu, Zengren Zhao
Pages: 1245-1255
Published online on: 13 February 2020

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Article Open Access

A radiomics model to predict the invasiveness of thymic epithelial tumors based on contrast‑enhanced computed tomography

Xiangmeng Chen, Bao Feng, Changlin Li, Xiaobei Duan, Yehang Chen, Zhi Li, Zhuangsheng Liu, Chaotong Zhang, Wansheng Long
Pages: 1256-1266
Published online on: 11 February 2020

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Article Open Access

Long non‑coding RNA LINC00858 promotes TP53‑wild‑type colorectal cancer progression by regulating the microRNA‑25‑3p/SMAD7 axis

Jidong Zhan, Jin Tong, Qiang Fu
Pages: 1267-1277
Published online on: 18 February 2020

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Article Open Access

Single‑cell RNA sequencing of t(8;21) acute myeloid leukemia for risk prediction

Qian Xiong, Sai Huang, Yong‑Hui Li, Na Lv, Chao Lv, Yi  Ding, Wen‑Wen Liu, Li‑Li Wang, Yang Chen, Liang Sun, Yi Zhao, Sheng‑You Liao, Michael Q. Zhang, Bao‑Li Zhu, Li Yu
Pages: 1278-1288
Published online on: 18 February 2020

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Article Open Access

RUNX3 inhibits the invasion and migration of esophageal squamous cell carcinoma by reversing the epithelial‑mesenchymal transition through TGF‑β/Smad signaling

Zhaohua Xiao, Yu Tian, Yang Jia, Qi Shen, Wenpeng Jiang, Gang Chen, Bin Shang, Mo Shi, Zhou Wang, Xiaogang Zhao
Pages: 1289-1299
Published online on: 21 February 2020

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Article Open Access

MicroRNA‑126‑3p suppresses HeLa cell proliferation, migration and invasion, and increases apoptosis via the PI3K/PDK1/AKT pathway

Ryoko Ichikawa, Rie Kawasaki, Aya Iwata, Sayaka Otani, Eiji Nishio, Hiroyuki Nomura, Takuma Fujii
Pages: 1300-1308
Published online on: 21 February 2020

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Article

Oroxylin A exerts anticancer effects on human ovarian cancer cells via the PPARγ‑dependent reversal of the progesterone receptor membrane component 1/2 expression profile

Jian‑Jiang Shen, Xiao‑Fei Zhu, Juan Xu, Zhi‑Fei Wang, Wan‑Jian Gu, Yun Chen
Pages: 1309-1318
Published online on: 21 February 2020

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Article

Cutaneous neurofibroma cells with active YAP promotes proliferation of macrophages resulting in increased accumulation of macrophages by modulating CCL5 and TGF‑β1

Jing Jia, Haibao Zhang, Lin He, Hongke Zhang, Maoguo Shu
Pages: 1319-1330
Published online on: 21 February 2020

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Article

Tumor necrosis factor‑related apoptosis‑inducing ligand as a therapeutic option in urothelial cancer cells with acquired resistance against first‑line chemotherapy

Stefan Vallo, Henner Stege, Maximilian Berg, Martin Michaelis, Ria Winkelmann, Florian Rothweiler, Jindrich Cinatl
Pages: 1331-1337
Published online on: 03 February 2020

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Article

DEK promotes the proliferation and invasion of lung cancers and indicates poor prognosis in lung adenocarcinomas

Mai‑Qing Yang, Lin‑Lin Bai, Lei Lei, Yi‑Wen Zheng, Zhao Wang, Zhi‑Han Li, Chen‑Chen Liu, Wen‑Jing Huang, Hong‑Tao Xu
Pages: 1338-1348
Published online on: 03 February 2020

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Correction Open Access

[Corrigendum] In vitro and in vivo activities of an antitumor peptide HM-3: A special dose-efficacy relationship on an HCT‑116 xenograft model in nude mice

Sitelbanat Yassin, Jialiang Hu, Hanmei Xu, Ce Li, Sarra Setrerrahmane
Pages: 1349-1349
Published online on: 13 February 2020

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Journal Cover
March-2026 Volume 55 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Collaborative breakthroughs in precision diagnosis and treatment of nasopharyngeal cancer: Biomarker‑driven screening and endoscopic minimally invasive surgery reshape the new paradigm of early intervention (Review)

E Jin, Wang Lin, Xiandong Zeng
Article Number: 53
Published online on: 23 January 2026

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Review Open Access

Key immune cells in the tumor immune microenvironment of colorectal cancer: Roles and research advances (Review)

Ming Qiu, Chongyuan Lan, Minglin Lin, Hui Ma
Article Number: 52
Published online on: 21 January 2026

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Correction Open Access

[Corrigendum] Icaritin acts synergistically with epirubicin to suppress bladder cancer growth through inhibition of autophagy

Xiu-Wu Pan, Lin Li, Yi Huang, Hai Huang, Dan-Feng Xu, Yi Gao, Lu Chen, Ji-Zhong Ren, Jian-Wei Cao, Yi Hong, Xin-Gang Cui
Article Number: 51
Published online on: 21 January 2026

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Review Open Access

Epigenetic mechanisms and therapeutic advances in diffuse midline glioma (Review)

Wenbo Wu, Wenlin Chen, Wenbin Ma, Yu Wang
Article Number: 50
Published online on: 20 January 2026

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Review Open Access

Recapitulating lung cancer metastasis in vitro: Advances in organoid models and challenges in clinical translation (Review)

Jian Jiang, Guomin Dong, Zhiyun Zhang, Xiaoyuan Lei, Fanshu Huang, Suoni Li, Jiequn Ma, Jie Bai, Qian Ge, Hui Wei, Zheng Zhao
Article Number: 49
Published online on: 20 January 2026

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Article Open Access

GPR176 enhances the epithelial‑mesenchymal transition in gastric cancer cells by activating the PI3K/AKT/mTOR signaling pathway

Guangchuan Mu, Kaiyan Li, Chaozhen Hu, Jintao Cai, Huichao Ruan, Guanyu Zhu, Dang Liu
Article Number: 48
Published online on: 19 January 2026

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Article Open Access

HMBOX1 inhibits hepatocellular carcinoma progression via PTPN1 mediated AKT1 phosphorylation

Chenning Zhang, Yu Jiang, Jiahui Liu, Wenyu Zhang, Jie Qi, Qing Wen, Hengli Zhao
Article Number: 47
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] Prognostic significance of miR‑218 in human hepatocellular carcinoma and its role in cell growth

Kangsheng Tu, Chao Li, Xin Zheng, Wei Yang, Yingmin Yao, Qingguang Liu
Article Number: 46
Published online on: 19 January 2026

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Review Open Access

Tumor microenvironment in bone sarcomas: Implications for immunotherapy and emerging therapeutic vulnerabilities (Review)

Wentao Li, Lijun Lv, Yibin Jin, Xin Yuan
Article Number: 45
Published online on: 16 January 2026

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Review Open Access

Immunotherapy after EGFR‑TKI treatment in advanced non‑small cell lung cancer: Current status and future perspectives (Review)

Huiyuan Ma, Longhui Li, Conghan Jiao, Yanyan Cheng, Jiayu He, Chen Jiang, Qian Tong, Dan Yi, Ying Zhang
Article Number: 44
Published online on: 16 January 2026

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Correction Open Access

[Corrigendum] Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin‑resistant SKOV3/DDP ovarian cancer cells

Yanying Zhong, Fuyin Le, Jiao Cheng, Chen Luo, Xiali Zhang, Xingwu Wu, Fang Xu, Qi Zuo, Buzhen Tan
Article Number: 43
Published online on: 13 January 2026

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Review Open Access

Role of tumor‑infiltrating lymphocytes and miR‑155 in breast cancer: Insights into carcinogenesis and their potential as prognostic biomarkers (Review)

Miriam Monteiro Alvares‑Vilela, Franciele Schlemmer, Sabrina Simplício de Araújo Romero Ferrari, Mary-Ann Elvina Xavier, Ricardo Titze‑de‑Almeida
Article Number: 42
Published online on: 14 January 2026

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Article Open Access

CDK1 depletion suppresses glioma malignancy through cell cycle pathway regulation: Mechanistic insights from functional and molecular profiling

Yu Wang, Huandi Zhou, Xuetao Han, Dongdong Zhang, Liubing Hou, Haonan Li, Tianyi Fan, Sijie Li, Xiaoying Xue
Article Number: 41
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] Downregulated microRNA‑200a promotes EMT and tumor growth through the Wnt/β‑catenin pathway by targeting the E‑cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma

Ningning Cong, Ping Du, Anling Zhang, Fajuan Shen, Juan Su, Peiyu Pu, Tao Wang, Jie Zjang, Chunsheng Kang, Qingyu Zhang
Article Number: 40
Published online on: 12 January 2026

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Review Open Access

Advances in targeting KRAS mutations: A promising approach for the treatment of non‑small cell lung cancer (Review)

Upesh Sharma, Jincheng Song, Hemraj Kandu, Yue Zhu, Zhaoxia Dai
Article Number: 39
Published online on: 08 January 2026

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Correction Open Access

[Corrigendum] CXCR6 predicts poor prognosis in gastric cancer and promotes tumor metastasis through epithelial-mesenchymal transition

Jie-Jie Jin, Fa-Xiang Dai, Zi-Wen Long, Hong Cai, Xiao-Wen Liu, Ye Zhou, Qi Hong, Qiong-Zhu Dong, Ya-Nong Wang, Hua Huang
Article Number: 38
Published online on: 05 January 2026

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Journal Cover
April-2026 Volume 55 Issue 4

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

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