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Experimental and Therapeutic Medicine
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-February 2011 Volume 2 Issue 1

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Impact Factor: 2.3

Review

Induced pluripotent stem cell technology and stem cell therapy for diabetes (Review)

Robert J. Drummond, Tilo Kunath, P. Joseph Mee, James A. Ross
Pages: 3-7
Published online on: 02 December 2010

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Article Open Access

Immunohistochemical analysis of integrins αvβ3, αvβ5 and α5β1, and their ligands, fibrinogen, fibronectin, osteopontin and vitronectin, in frozen sections of human oral head and neck squamous cell carcinomas

Eva-Maria Fabricius, Gustav-Paul Wildner, Ute Kruse-Boitschenko, Bodo Hoffmeister, Simon L. Goodman, Jan-Dirk Raguse
Pages: 9-19
Published online on: 02 December 2010

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Article

Tumor necrosis factor-α induces transcriptional activation of nuclear factor-κB in insulin-producing β-cells

Jai Parkash
Pages: 21-26
Published online on: 27 October 2010

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Article

Up-regulation of microRNAs, miR21 and miR23a in human liver cancer cells treated with Coptidis rhizoma aqueous extract

Meifen Zhu, Ning Wang, Sai-Wah Tsao, Man-Fung Yuen, Yigang Feng, Thomas S.K. Wan, Kwan Man, Yibin Feng
Pages: 27-32
Published online on: 19 November 2010

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Article

Antioxidant and antitumor activities of water extracts from the root of Actinidia kolomikta

Di Guan, Zhenya Zhang, Yingnan Yang, Norio Sugiura, Honghai  Hu, Guoqing Xing, Jiqiang Liu, Xiaoyan Zu, Ying Zhang
Pages: 33-39
Published online on: 10 November 2010

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Article

Ostrich produce cross-reactive neutralization antibodies against pandemic influenza virus A/H1N1 following immunization with a seasonal influenza vaccine

Kazuhide Adachi, Kentaro Takama, Masaya Tsukamoto, Marie Inai, Ekowati Handharyani, Satoshi Hiroi, Yasuhiro Tsukamoto
Pages: 41-45
Published online on: 02 December 2010

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Article

Predicting response of bladder cancers to gemcitabine and carboplatin neoadjuvant chemotherapy through genome-wide gene expression profiling

Yoichiro Kato, Hitoshi Zembutsu, Ryo Takata, Fuyuki Miya, Tatsuhiko Tsunoda, Wataru Obara, Tomoaki Fujioka, Yusuke Nakamura
Pages: 47-56
Published online on: 30 November 2010

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Article

Suppressive action of resolvin D1 on the production and release of septic mediators in D-galactosamine‑sensitized endotoxin shock mice

Taisuke Murakami, Kaori Suzuki, Hiroshi Tamura, Isao Nagaoka
Pages: 57-61
Published online on: 02 December 2010

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Article

Reduced expression of TRF1 is associated with tumor progression and poor prognosis in oral squamous cell carcinoma

Hui-Ching Chuang, Chang-Han Chen, Chao-Cheng Huang, Fu-Min Fang, Hsin-Ting Tsai, Chih-Yen Chien
Pages: 63-67
Published online on: 02 December 2010

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Article Open Access

Establishment of a triple-negative type human breast cancer cell line that selectively metastasizes to the lung after orthotropic implantation

Mamoru Nukatsuka, Hitoshi Saito, Masakazu Fukushima
Pages: 69-72
Published online on: 02 December 2010

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Article Open Access

Phase I clinical trial of a novel peptide vaccine in combination with UFT/LV for metastatic colorectal cancer

Kiyotaka Okuno, Fumiaki Sugiura, Jin-ichi Hida, Tadao Tokoro, Eizaburo Ishimaru, Yasushi Sukegawa, Kazuki Ueda
Pages: 73-79
Published online on: 02 December 2010

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Article

Prevalence of type 2 diabetes mellitus in Japanese patients with hepatocellular carcinoma

Naota Taura, Tatsuki Ichikawa, Hisamitsu Miyaaki, Hiroshi Yatsuhashi, Hiromi Ishibashi, Kazuhiko Nakao
Pages: 81-84
Published online on: 02 December 2010

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Article

Glial fibrillary acidic protein is one of the key factors underlying neuron-like elongation in PC12 cells

Maki Sugaya-Fukasawa, Toru Watanabe, Michiko Tamura, Satsuki Egashira, Hisashi Hisatomi
Pages: 85-87
Published online on: 05 November 2010

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Article

Route of primary HTLV-1 infection regulates HTLV-1 distribution in reservoir organs of infected mice

Masakazu Tanaka, Takayuki Nitta, Binlian Sun, Jun-Ichi Fujisawa, Masanao Miwa
Pages: 89-93
Published online on: 02 December 2010

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Article

Evaluation of an inflammation-based prognostic score for the identification of patients requiring postoperative adjuvant chemotherapy for stage II colorectal cancer

Yuji Toiyama, Chikao Miki, Yasuhiro Inoue, Koji Tanaka, Yasuhiko Mohri, Masato Kusunoki
Pages: 95-101
Published online on: 02 December 2010

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Article

Therapeutic potential of the TWEAK/Fn14 pathway in intractable gastrointestinal cancer

Ryo Yoriki, Satoru Akashi, Masayuki Sho, Takeo Nomi, Ichiro Yamato, Kiyohiko Hotta, Tomoyoshi Takayama, Sohei Matsumoto, Kohei Wakatsuki, Kazuhiro Migita, Hideo Yagita, Yoshiyuki Nakajima
Pages: 103-108
Published online on: 02 December 2010

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Article

Phase I clinical study of a personalized peptide vaccination available for six different human leukocyte antigen (HLA-A2, -A3, -A11, -A24, -A31 and -A33)-positive patients with advanced cancer

Akira Yamada, Masanori Noguchi, Nobukazu Komatsu, Shigetaka  Suekane, Shigeru  Yutani, Fukuko Moriya, Takashi Mine, Kosuke  Momozono, Koichiro Kawano, Kyogo Itoh
Pages: 109-117
Published online on: 02 December 2010

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Article

Cytotoxic evaluation of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone in peripheral blood lymphocytes of patients with refractory solid tumors using electron paramagnetic resonance

Jill M. Kolesar, Kamakshi Sachidanandam, William R. Schelman, Jens Eickhoff, Kyle D. Holen, Anne M. Traynor, Dona B. Alberti, James P. Thomas, Christopher R. Chitambar, George Wilding, William E. Antholine
Pages: 119-123
Published online on: 30 November 2010

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Article

Chemical and biological analysis of active free and conjugated bile acids in animal bile using HPLC-ELSD and MTT methods

Ning Wang, Yibin Feng, Tang Ning Xie, Weiwei Su, Meifen Zhu, Oiyee Chow, Yanbo Zhang, Kwan-Ming Ng, Chung-Hang Leung, Yao Tong
Pages: 125-130
Published online on: 02 December 2010

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Article

Patient outcome prediction using multiple biomarkers in human melanoma: A clinicopathological study of 118 cases

Jun Li, Zhizhong Zhang, Gang Li
Pages: 131-135
Published online on: 02 December 2010

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Article

Frequent expression of MAGE1 tumor antigens in bronchial epithelium of smokers without lung cancer

Manisha Bhutani, Ashutosh Kumar Pathak, Hongli Tang, You H. Fan, Diane D. Liu, J. Jack Lee, Jonathan Kurie, Rodolfo C. Morice, Waun Ki Hong, Li Mao
Pages: 137-142
Published online on: 02 December 2010

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Article

Antioxidant activity and antiapoptotic effect of Asparagus racemosus root extracts in human lung epithelial H460 cells

Lalana Kongkaneramit, Wasu Witoonsaridsilp, Penchom Peungvicha, Kornkanok Ingkaninan, Neti Waranuch, Narong Sarisuta
Pages: 143-148
Published online on: 02 December 2010

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Article

IGF1 mRNA isoform expression in the cervix of HPV-positive women with pre-cancerous and cancer lesions

Maria Magdalena Koczorowska, Anna Kwasniewska, Anna Gozdzicka-Jozefiak
Pages: 149-156
Published online on: 02 December 2010

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Article

Metastasis tumour suppressor-1 and the aggressiveness of prostate cancer cells

Noha Mustafa, Tracey A. Martin, Wen G. Jiang
Pages: 157-162
Published online on: 02 December 2010

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Journal Cover
July-2026 Volume 32 Issue 1

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Impact Factor: 2.3

Article Open Access

Amplification of heterogeneous nuclear ribonucleoprotein A/B aids in immune infiltration regulation and breast cancer tumorigenesis

Jiachao Xu, Qian Han, Libin Chen, Min Yang, Jun Huang, Shanhong Lin, Shengmin Zhang
Article Number: 198
Published online on: 27 May 2026

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Retraction Open Access

[Retracted] Novel triazole analogs of apigenin‑7‑methyl ether exhibit potent antitumor activity against ovarian carcinoma cells via the induction of mitochondrial‑mediated apoptosis

Yuyan Qi, Zhaoxia Ding, Yushuang Yao, Dehua Ma, Feifei Ren, Hongjuan Yang, Aiping Chen
Article Number: 197
Published online on: 26 May 2026

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Article Open Access

Meta‑analysis of the efficacy of reverse total shoulder arthroplasty and open reduction and internal fixation in the treatment of proximal humerus fractures

Yuan Li, Meng-Xuan Niu, Fang-Zheng He, Xin Qin, Wei-Wei Wang, Peng-Fei Han
Article Number: 196
Published online on: 21 May 2026

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Article Open Access

Fatty acid‑activated proton transporter SR4 prevents hepatic steatosis and metabolic alterations in diabetic mice by improving mitochondria function, energy balance and oxidative stress

James Figarola, Jyotsana Singhal, Sharad Singhal
Article Number: 195
Published online on: 20 May 2026

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Expression of Concern Open Access

[Expression of Concern] Endogenous Nampt upregulation is associated with diabetic nephropathy inflammatory‑fibrosis through the NF‑κB p65 and Sirt1 pathway; NMN alleviates diabetic nephropathy inflammatory‑fibrosis by inhibiting endogenous Nampt

Ye Chen, Yuzhen Liang, Tingting Hu, Riming Wei, Congjie Cai, Ping Wang, Lingyu Wang, Wei Qiao, Leping Feng
Article Number: 194
Published online on: 20 May 2026

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Article Open Access

Impact of vitamin D receptor gene variants on psoriasis vulgaris susceptibility and clinical phenotype in a Greek population

Polytimi Sidiropoulou, Martha Katsarou, Maria Papasavva, Annia Tsolakou, Akylas Fotiadis, Demetrios A. Spandidos, Natalia Rompoti, Irene Stefanaki, Alexander J. Stratigos, Nikolaos Drakoulis, Electra Nicolaidou
Article Number: 193
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Resistin increases the expression of NOD2 in mouse monocytes

Yi Ren, Taomei Wan, Zhicai Zuo, Hengmin Cui, Xi Peng, Jing Fang, Junliang Deng, Yanchun Hu, Shuming Yu, Liuhong Shen, Xiaoping Ma, Ya Wang, Zhihua Ren
Article Number: 192
Published online on: 18 May 2026

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Case Report Open Access

Morphological analysis of bronchoalveolar lavage fluid in diagnosing pulmonary aspergilloma in a patient with rheumatoid arthritis: A case report

Yuli Zhou, Yuyi Lai, Fuxian Zhou, Xinxin Wang, Xiao He, Juan Jin, Ruikai Zhang
Article Number: 191
Published online on: 14 May 2026

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Case Report Open Access

Intravenous leiomyomatosis of the uterus: A case report and literature review

Yuzhen Zhao, Fei Tian
Article Number: 190
Published online on: 14 May 2026

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Case Report Open Access

3D‑Printed prosthesis for recurrent femoral metastasis with periprosthetic infection: A case report

Jiangbi Li, Yangjie Zhang, Jianping Kang, Changping Tian, Suolin Chen, Ya Ning, Haixia Li, Yanbin Xiao
Article Number: 189
Published online on: 14 May 2026

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Correction Open Access

[Corrigendum] Targeting Sirt1 in a rat model of high‑fat diet‑induced non‑alcoholic fatty liver disease: Comparison of Gegen Qinlian decoction and resveratrol

Yi Guo, Jun-Xiang Li, Tang-You Mao, Wei-Han Zhao, Li-Juan Liu, Yun-Liang Wang
Article Number: 188
Published online on: 13 May 2026

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Article Open Access

Glycolytic reprogramming in host response to Borrelia burgdorferi: A gene signature revealed by integrative bioinformatics analysis and machine learning

Yan Dong, Yantong Chen, Yanshuang Luo, Meng Liu, Chao Song, Xuesong Chen, Fusong Yang, Qingyi Luo, Guozhong Zhou
Article Number: 187
Published online on: 12 May 2026

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Retraction Open Access

[Retracted]Oblongifolin C reverses GEM resistance via suppressing autophagy flux in bladder cancer cells

Zhilong Huang, Tingting Wang, Wenjun Xia, Qing Li, Xinlei Chen, Xiaoli Liu, Peng Wei, Wenping Xu, Meirong Lv
Article Number: 186
Published online on: 11 May 2026

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Article Open Access

Genetic etiology and phenotypic characteristics of fetuses with 11q deletion syndrome (11q23.3‑q25)

Tong Zhang, Xiaoyi Cong, Zhenming Li, Xianzhen Cao, Liang Hu, Xiaojin Luo, Yanan Liu, Weiqiang Liu, Fengxiang Wei
Article Number: 185
Published online on: 08 May 2026

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Article Open Access

CDX2‑UPK1B‑PIK3IP1‑PI3K/AKT signaling axis regulates gastric cancer cell invasion and migration and influences patient prognosis

Shaodong Zhong, Heng Zhang, Jin Huang
Article Number: 184
Published online on: 08 May 2026

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Review Open Access

Modulation of the tumor microenvironment by incretins and glucagon: Metabolic and immune mechanisms (Review)

Min Hu, Chang-Jun Jiang, Cheng Yi
Article Number: 183
Published online on: 08 May 2026

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Article Open Access

TPX2 as a prognostic biomarker and potential therapeutic target for malignant melanoma proliferation and metastasis

Fuqi Li, Ronghui Yang, Zhixian Wu
Article Number: 182
Published online on: 08 May 2026

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Review Open Access

Benefits and mechanisms of polysaccharides derived from traditional Chinese medicine for ulcerative colitis treatment (Review)

Yuebo Jia, Zheng Jiao, Lingshuo Bai, Gege Li, Lijian Pang
Article Number: 181
Published online on: 08 May 2026

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Retraction Open Access

[Retracted] Synergistic inhibition of leukemia WEHI‑3 cell growth by arsenic trioxide and Hedyotis diffusa Willd extract in vitro and in vivo

Yu-Jui Kuo, Yan-Jin Liu, Tzong-Der Way, Su-Yin Chiang, Jaung-Geng Lin, Jing-Gung Chung
Article Number: 180
Published online on: 29 April 2026

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Journal Cover
August-2026 Volume 32 Issue 2

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Impact Factor: 2.3

Article Open Access

Ginkgo biloba extract 50 dropping pills improve vascular cognitive impairment through anti‑oxidative and anti‑inflammatory effects

Fu-Ling Wang, Wen-Lan Li, Hong Li
Article Number: 215
Published online on: 12 June 2026

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Case Report Open Access

Sequential fulminant hepatitis and toxic epidermal necrolysis induced by tislelizumab: A case report

Zhuo Wang, Chao Li, Lili Yue
Article Number: 214
Published online on: 12 June 2026

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Article

A study of 25‑(OH)D3 levels in children with type 1 diabetes mellitus and its influencing factors

Xiaojuan Chen, Xitian Fan, Jinshu Wei, Jianing Xie, Xiaoya Yu, Guoquan Fan, Jingjing Wei
Article Number: 213
Published online on: 12 June 2026

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Article

Outcomes of transanal total mesorectal excision with ultra‑low anterior resection: A single institute propensity‑matched cohort study

Pushkar Prasad Kute, Shiki Fujino, Suellyn Centauri, Ellathios Antoniou, Krishanth Naidu, Asiri Arachchi, Vignesh Narasimhan, Thomas Surya Suhardja, Yeng Kwang Tay, James Lim, Chaminda Saranasuriya, Thang Chien Nguyen, William Teoh, Hanumant Chouhan
Article Number: 212
Published online on: 11 June 2026

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Article Open Access

Antioxidant and anti‑inflammatory effects of the extract from rhizomes of Belamcanda chinensis (L.) DC. on human keratinocyte HaCaT cells

Sang Eun Ha, Hun Hwan Kim, Se Hyo Jeong, Gon Sup Kim, Kwang Hyun Hwang
Article Number: 211
Published online on: 11 June 2026

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Case Report Open Access

Immune‑related nephritis, ureteritis and cystitis secondary to immune checkpoint inhibitors: A case report and review of the literature

Guangquan Zhang, Silu Xu, Jing Wu, Qianqian Gao, Yanzhi Bi, Min Xiao
Article Number: 210
Published online on: 08 June 2026

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Retraction Open Access

[Retracted] Acaricidal activity of extracts from Ligularia virgaurea against the Sarcoptes scabiei mite in vitro

Biao Luo, Fei Liao, Yanchun Hu, Xi Liu, Yajun He, Lei Wu, Hui Tan, Lijuan Luo, Yancheng Zhou, Quan Mo, Junliang Deng, Yahui Wei
Article Number: 209
Published online on: 08 June 2026

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Case Report Open Access

Epithelioid fibrous histiocytoma of eyelid in children: A case report

Zheng Sun, Zhaoxia Zhai, Yutian Li, Peiyan Shi, Wei Cheng, Jinling Ge, Yanfei Li
Article Number: 208
Published online on: 05 June 2026

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Article

Stevens‑Johnson syndrome induced by fluoroquinolones in a patient with colon cancer: A case report and literature review

Yuan Zhou, Guangye Huang, Hongxia Li
Article Number: 207
Published online on: 04 June 2026

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Article Open Access

Sotagliflozin ameliorates doxorubicin-induced cardiomyopathy by regulating inflammation and mitochondrial dysfunction through the AMPK/mTOR pathway

Haifeng Liu, Danye Han, Meiling Li
Article Number: 206
Published online on: 04 June 2026

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Article Open Access

Integrated network pharmacology and serum metabolomics to reveal the protective mechanism of methanolic extract of BaiYangJie on cisplatin‑induced acute kidney injury in mice

Bin Xia, Jianglong Chen, Jinhui Wang, Dalong Li, Lixia Zhang, Jing Su, Xuan Ding, Yana Lv, Shifang Liu, Xue Zhang, Tianzhen Wan, Guang Li
Article Number: 205
Published online on: 04 June 2026

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Article Open Access

Screening criteria for drainage-free patients after retroperitoneal laparoscopic adrenal tumor resection and their prospective validation study value

Yan Zhao, Yu-Xuan He, Hai-Tao Li, Jing-Yi Cao, Bing Zhong, Hui Zhou
Article Number: 204
Published online on: 04 June 2026

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Retraction Open Access

[Retracted] Atorvastatin increases lipopolysaccharide‑induced expression of tumour necrosis factor‑α‑induced protein 8‑like 2 in RAW264.7 cells

Ming-Wei Liu, Mei-Xian Su, Wei Zhang, Li Wang, Chuan-Yun Qian
Article Number: 203
Published online on: 02 June 2026

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Case Report Open Access

LMNA c.1622G>A mutation and myopathic changes in a family with limb‑girdle muscular dystrophy: A case report

Yanling Zhu, Qiushi Wang, Tiefeng Zhang
Article Number: 202
Published online on: 02 June 2026

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Case Report Open Access

Optimizing management of immune checkpoint inhibitor‑induced inflammatory arthritis: A case series and literature review

Yuanyuan Wang, Yingmei Wen, Jinxiong Xia, Hongyan Feng, Fei Wu, Dafu Ye, Yanjun Gao, Qingqing Li, Yi Yao
Article Number: 201
Published online on: 29 May 2026

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Article Open Access

Tumor Treating Fields modulate apoptotic and immune programs in T‑cell acute lymphoblastic leukemia cell lines

Jinju Heo, Myonggeun Yoon
Article Number: 200
Published online on: 29 May 2026

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Case Report

Complete ureteral duplication with occult calculi: A case report

Haiyan Zheng, Li Wang, Rui Yang, Shenghao Niu, Faying Yang, Jiaxi Yao
Article Number: 199
Published online on: 29 May 2026

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