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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2003 Volume 12 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Delivery of recombinant adeno-associated virus by jet injection

Olga Janouskova, Thomas Nellessen, Jitka Stokrova, Pavel Jinoch, Michal Smahel
Pages: 687-691
Published online on: 01 November 2003

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Article

E-cadherin-dependent intercellular adhesion enhances chemoresistance

Tomoaki Nakamura, Yasushi Kato, Hidenori Fuji, Tetsuya Horiuchi, Yukio Chiba, Kuniyoshi Tanaka
Pages: 693-700
Published online on: 01 November 2003

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Article

Treatment of ulcerative colitis patients by long-term administration of germinated barley foodstuff: Multi-center open trial

Osamu Kanauchi, Keiichi Mitsuyama, Terasu Homma, Kazuya Takahama, Yoshihide Fujiyama, Akira Andoh, Yoshio Araki, Toshihiro Suga, Toshifumi Hibi, Makoto Naganuma, Hitoshi Asakura, Hiroshi Nakano, Takashi Shimoyama, Nobuyuki Hida, Ken Haruma, Hideki Koga, Michio Sata, Nobuo Tomiyasu, Atsushi Toyonaga, Masanobu Fukuda, Atsushi Kojima, Tadao Bamba
Pages: 701-704
Published online on: 01 November 2003

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Article

Overexpression of X-linked inhibitor of apoptosis in human hepatocellular carcinoma

Katsuya Shiraki, Kazushi Sugimoto, Yutaka Yamanaka, Yumi Yamaguchi, Yukiko Saitou, Keiichi Ito, Norihiko Yamamoto, Takenari Yamanaka, Katsuhiko Fujikawa, Kazumoto Murata, Takeshi Nakano
Pages: 705-708
Published online on: 01 November 2003

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Article

Overexpression of cyclooxygenase-2 protein and its relationship to apoptosis in cervical carcinoma treated with neoadjuvant chemotherapy

Nobutaka Nagai, Xiurong Tian, Keiji Mukai, Eiji Hirata, Tomoyo Kusuda, Yuko Shiroyama, Kazushi Shigemasa, Koso Ohama
Pages: 709-714
Published online on: 01 November 2003

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Article

Differential expression of homing receptor CD103 on lamina propria lymphocytes and association of CD103 with epithelial adhesion molecules in inflammatory bowel disease

Nobuhide Oshitani, Kenji Watanabe, Kiyoshi Maeda, Yasuhiro Fujiwara, Kazuhide Higuchi, Takayuki Matsumoto, Tetsuo Arakawa
Pages: 715-719
Published online on: 01 November 2003

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Article

N-3 fatty acid-rich diet prevents early response of interleukin-6 elevation in trinitrobenzene sulfonic acid-induced enteritis

Akira Andoh, Tomoyuki Tsujikawa, Izumi Ishizuka, Yoshio Araki, Masaya Sasaki, Shigeki Koyama, Yoshihide Fujiyama
Pages: 721-725
Published online on: 01 November 2003

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Article

11q23-24 loss is associated with chromosomal instability in endometrial cancer

Keiko Kawasaki, Yutaka Suehiro, Kenji Umayahara, Hitoshi Morioka, Takehisa Ito, Toshiaki Saito, Naoki Tsukamoto, Norihiro Sugino, Hiroshi Kato, Kohsuke Sasaki
Pages: 727-731
Published online on: 01 November 2003

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Article

Induction of apoptosis by Se-MSC in U937 human leukemia cells through release of cytochrome c and activation of caspases and PKC-δ: mutual regulation between caspases and PKC-δ via a positive feedback mechanism

Byeong-Churl Jang, Eun-Seok Choi, Ki-Jo Im, Won-Ki Baek, Taek Kyu Kwon, Min-Ho Suh, Sang-Pyo Kim, Jong-Wook Park, Seong-Il Suh
Pages: 733-739
Published online on: 01 November 2003

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Article

Mechanism of thermotolerance induction by split-dose hyperthermia in Deinococcus radiodurans DNA repair deficient mutants

Kazuki Harada, Mami Ando, Tomoko Fujimura-Ito, Mika Kasahara-Imamura, Yoshihiko Sako, Aritsune Uchida, Yuzaburo Ishida, Hajime Kadota, Takeo Ohnishi, Bevan E.B. Moseley
Pages: 741-747
Published online on: 01 November 2003

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Article

Genotypes of CCR2 and CCR5 chemokine receptors in human myasthenia gravis

Xiaoyan Zhao, Baback Gharizadeh, Peter Hjelmström, Ritva Pirskanen, Pål Nyrén, Ann-Kari Lefvert, Mehran Ghaderi
Pages: 749-753
Published online on: 01 November 2003

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Article

Preventive effect of zinc acexamate administration in streptozotocin-diabetic rats: Restoration of bone loss

Masayoshi Yamaguchi, Satoshi Uchiyama
Pages: 755-761
Published online on: 01 November 2003

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Article

Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-3 (E-NPP3/CD203c/PD-Iβ/B10/gp130RB13-6) in human colon carcinoma

Yoshihiko Yano, Yoshitake Hayashi, Kimihiko Sano, Hiroshi Shinmaru, Yoshikazu Kuroda, Hiroshi Yokozaki, Seitetsu Yoon, Masato Kasuga
Pages: 763-766
Published online on: 01 November 2003

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Article

RB1CC1 suppresses cell cycle progression through RB1 expression in human neoplastic cells

Keiichi Kontani, Tokuhiro Chano, Yoshitomo Ozaki, Noriaki Tezuka, Satoru Sawai, Shozo Fujino, Yukikazu Saeki, Hidetoshi Okabe
Pages: 767-769
Published online on: 01 November 2003

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Article

Molecular detection of free cancer cells in pleural lavage fluid from esophageal cancer patients

Shoji Natsugoe, Koki Tokuda, Masataka Matsumoto, Hiroshi Okumura, Akihiro Nakajo, Hiroyuki Takatori, Hiroshi Nakashima, Sumiya Ishigami, Sonshin Takao, Takashi Aikou
Pages: 771-775
Published online on: 01 November 2003

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Article

Ghrelin clearance is reduced at the late stage of polymicrobial sepsis

Rongqian Wu, Mian Zhou, Xiaoxuan Cui, H. Hank Simms, Ping Wang
Pages: 777-781
Published online on: 01 November 2003

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Article

Identification and expression analysis of a novel splice variant of human Sprouty1 gene

Liu Wang, Chaoneng Ji, Hai Wu, Jian Xu, Qihan Wu, Jianfeng Dai, Gang Yin, Xin Ye, Shaohua Gu, Yi Xie, Yumin Mao
Pages: 783-787
Published online on: 01 November 2003

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Article

Experimental therapy of HPV16 induced tumors with IL12 expressed by recombinant vaccinia virus in mice

Sárka Nemeckova, Vojtech Sroller, Petr Hainz, Jitka Krystofova, Michal Smahel, L. Kutinova
Pages: 789-796
Published online on: 01 November 2003

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Article

Human soluble tumor-associated antigens promote the suppression of rat mammary tumors by 5-fluorouracil and stimulate the functional activity of immune organs: Experimental and morphological studies

George Kossoy, Herzl Ben-Hur, Ilana Avinoach, Asher Alhayany, David F. Shneider, Itshak Zusman
Pages: 797-801
Published online on: 01 November 2003

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Article

Differential effects of estradiol and raloxifene on collagen biosynthesis in cultured human skin fibroblasts

Arkadiusz Surazynski, Katarzyna Jarzabek, Jozef Haczynski, Piotr Laudanski, Jerzy Palka, Slawomir Wolczynski
Pages: 803-809
Published online on: 01 November 2003

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Review

WNT2 and human gastrointestinal cancer (Review)

Masaru Katoh
Pages: 811-816
Published online on: 01 November 2003

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Article

Identification and characterization of TRIP8 gene in silico

Masuko Katoh, Masaru Katoh
Pages: 817-821
Published online on: 01 November 2003

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

DUSP26: Unveiling a critical molecular mediator and therapeutic target in developmental dysplasia of the hip‑associated secondary osteoarthritis

Enbo Wang, Haixiang Zhang, Dechao Wu, Sadik Ali, Xianglu Ji
Article Number: 105
Published online on: 26 February 2026

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mTOR signaling pathway in primary Sjögren's syndrome: Pathogenesis and potential therapeutic targets (Review)

Rongxiu Huo, Yanting Yang, Chengcheng Wei, Yang Yang, Danli Meng, Jinying Lin, Xinxiang Huang
Article Number: 104
Published online on: 25 February 2026

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Bumetanide‑blocked SLC12A2 exerts a protective effect in experimental diabetic retinopathy

Yuting Zhang, Xiuli Wang, Qinyue Xie, Yue Huang, Dongjia Huang, Ziqing Liu, Tong Xu, Man Ni, Hongwei Yang
Article Number: 103
Published online on: 25 February 2026

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Article Open Access

Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 102
Published online on: 25 February 2026

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Retraction Open Access

[Retracted] A novel role for Livin in the response to ultraviolet B radiation and pterygium development

Shuang-Qing Wu, Qi-Bin Xu, Wen-Yan Sheng, Lin-Ya Su, Li-Wei Zhu
Article Number: 101
Published online on: 24 February 2026

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Article Open Access

Endothelial UNC5B regulates blood‑retinal barrier homeostasis

Yujia Yao, Suyu Wang, Jiajun Li, Qianzi Jin, Ziyi Chen, Qin Jiang, Keran Li
Article Number: 100
Published online on: 20 February 2026

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Review Open Access

Metabolic hubs in reproduction: The regulatory network of lipid droplets in gamete and embryo physiology (Review)

Liuzhu Pan, Zongzhuang Wen, Yi Jin
Article Number: 99
Published online on: 17 February 2026

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The role and mechanism of IL‑35 in myasthenia gravis (Review)

Jing Mao, Lin-Ming Zhang, Yan-Lin Zhu, Shu-Ji Gao, Ming-Wei Liu
Article Number: 98
Published online on: 17 February 2026

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Article Open Access

miRNA‑378a‑5p attenuates the development of abdominal aortic aneurysm via ABLIM1‑MKL1 signaling pathways

Jing Wang, Yujia Zou, Yani Wang, Zheming Yang, Daoshen Liu, Xiaolin Su, Haixu Song, Kai Xu, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 97
Published online on: 16 February 2026

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Review Open Access

Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review)

Yufei Zhong, Yunfei Zou, Zhuoyuan Yang, Junjun Wang, Zezheng Pan, Jiugeng Feng
Article Number: 96
Published online on: 16 February 2026

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Microglia‑mediated neuroinflammation in intracerebral hemorrhage: Pathological mechanisms and implications for therapeutic development (Review)

Xuehui Fan, Changzhi Pu, Luyi Zhong, Oucheng Wang, Binyi Zhao, Dongyi Liao, Xue Bai, Guiquan Chen, Guoqiang Yang
Article Number: 95
Published online on: 16 February 2026

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Correction Open Access

[Corrigendum] Silencing of Rac1 modifies lung cancer cell migration, invasion and actin cytoskeleton rearrangements and enhances chemosensitivity to antitumor drugs

Qing-Yong Chen, Li-Qun Xu, De-Min Jiao, Qing-Hua Yao, Yan-Yi Wang, Hui-Zhen Hu, Yu-Quan Wu, Jia Song, Jie Yan, Li-Jun Wu
Article Number: 94
Published online on: 12 February 2026

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Article Open Access

Orcinol glucoside ameliorates pulmonary fibrosis by suppressing hyaluronic acid synthesis and macrophage M2 polarization via targeting hyaluronic acid synthase 2

Caizi Li, Xinglinzi Tang, Xiaoru Luo, Xin Lai, Jing Yang, Zheng Xu, Gulizeba Muhetaer, Yizi Xie, Xiufang Huang, Hang Li
Article Number: 93
Published online on: 10 February 2026

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Helicobacter pylori and hyperglycemia fuel gastric cancer glycolysis: Mechanisms and targeted intervention (Review)

Youjia Liu, Fang Wang, Ya Deng, Yanxia Hu, Feihong Shu, Jie Yu, Guoyou Gou, Min Wen, Chen Luo, Xianmin Lu, Qian Du, Jingyu Xu, Rui Xie
Article Number: 92
Published online on: 09 February 2026

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Targeting the gut‑bone axis through exercise: A novel approach to osteoporosis prevention and treatment (Review)

Jingjing Wu, Siqi Zhang, Junjie Wu, Yuhang Luan, Xingchen Yao, Boyan Xu, Yiting Wang, Yingyue Sheng, Yuzheng Xue, Yilin Ren
Article Number: 91
Published online on: 09 February 2026

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Chorus line in oral squamous cell carcinoma: How stromal and immune players orchestrate tumor progression (Review)

Eliano Cascardi, Mario Della Mura, Nicoletta Sgarro, Silvia Minei, Gerardo Cazzato, Eugenio Maiorano, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Fábio França Vieira E Silva, Eleonora Lo Muzio, Mario Dioguardi, Andrea Ballini
Article Number: 90
Published online on: 09 February 2026

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Correction Open Access

[Corrigendum] Hsa_circularRNA_0079201 suppresses chondrocyte proliferation and endochondral ossification by regulating the microRNA‑140‑3p/SMAD2 signaling pathway in idiopathic short stature 

Xijuan Liu, Chen Yan, Xueqiang Deng, Jingyu Jia
Article Number: 89
Published online on: 09 February 2026

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Review Open Access

Post‑translational modifications in diabetic kidney disease (Review)

Mengfei He, Zihang Wang, Zhuang Miao, Yu Zhao, Lingling Wei, Lijie Zhang, Ruili Yin, Yan Wang, Longyan Yang
Article Number: 88
Published online on: 09 February 2026

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Review Open Access

Role of vascular smooth muscle cell pathobiology in sepsis‑induced vasoplegia (Review)

Hang Ruan, Xiao-Yan Shen, Shi-Yan Liu, Shu-Sheng Li
Article Number: 87
Published online on: 06 February 2026

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Review Open Access

Signalling pathways regulated by FSTL1 in inflammation and potential therapeutic applications (Review)

Changliang Ma, Jingxin Li, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Wencui Li, Zhiqin Deng, Zhe Zhao
Article Number: 86
Published online on: 05 February 2026

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Article Open Access

Hypothermic machine perfusion protects DCD graft liver from ischemia‑reperfusion injury by enhancing macrophage efferocytosis via KLF2‑NLRP3 signaling

Qin Deng, Zhongzhong Liu, Qifa Ye, Jia Liu, Zhihui Fu, Xingjian Zhang, Jun Luo, Zhongshan Lu, Pengpeng Yue, Jiansheng Xiao, Qi Xiao
Article Number: 85
Published online on: 05 February 2026

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Mechanistic advances in exercise‑mediated regulation of autophagy dysfunction in Alzheimer's disease (Review)

Wei Li, Wen-Hong Wang, Yi Song, Xu-Jiong Li, Yan Li, Xia Wang, Ting-Ting Tian, Xiao Huang, Li Zhao
Article Number: 84
Published online on: 04 February 2026

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Correction Open Access

[Corrigendum] p57KIP2‑mediated inhibition of human trophoblast apoptosis and promotion of invasion in vitro

Guo-Qian He, Guang-Yu Liu, Wen-Ming Xu, Hui-Juan Liao, Xing-Hui Liu, Guo-Lin He
Article Number: 83
Published online on: 04 February 2026

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Review Open Access

Lipid droplets beyond storage: Cellular metabolic modulator in the diabetic heart (Review)

Yongchun Liang, Xinbiao Fan, Xiaofei Geng, Yunfeng Jia, Wenyu Shang, Xitong Sun, Jun Ge, Guijun Ye, Boyu Zhu, Zheng Zhang, Yuxin Kang, Xiaoyu Shan, Junping Zhang
Article Number: 82
Published online on: 03 February 2026

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Review Open Access

IMP metabolic mechanisms and IMPDH targeting strategies in tumor metabolic reprogramming and therapy (Review)

Hao Zhu, Hao Wang, Xia Li, Weisong Zhang, Yihao Wang, Qingze Tan, Dongxu Ying, Zhan Shi, Jianxiang Song
Article Number: 81
Published online on: 03 February 2026

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Article Open Access

Ebastine targets HER2/HER3 signaling and cancer stem cell traits to overcome trastuzumab resistance in HER2‑positive breast cancer

Eunsun Jung, Ji Young Kim, Dongmi Ko, Juyeon Seo, Sang Yoon Lee, Daeun Lee, Subeen Kim, Minsu Park, Seongjae Kim, Soeun Park, Kyoungmin Lee, Yong Koo Kang, Kee Dal Nam, Yoon-Jae Kim, Jae Hong Seo
Article Number: 80
Published online on: 02 February 2026

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Correction Open Access

[Corrigendum] Inhibition of acid‑sensing ion channel 1a attenuates acid‑induced activation of autophagy via a calcium signaling pathway in articular chondrocytes

Wen-Fan Gao, Ya-Yun Xu, Jin-Fang Ge, Fei-Hu Chen
Article Number: 79
Published online on: 02 February 2026

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Immunological mechanisms and novel therapeutic strategies for sepsis‑associated acute kidney injury (Review)

Lu Xu, Wei Jiang, Lin Song, Jing Wang, Jiangquan Yu, Ruiqiang Zheng
Article Number: 78
Published online on: 30 January 2026

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Correction Open Access

[Corrigendum] Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury

Fanlan Meng, Jun Li, Xiao Yang, Xiaoyong Yuan, Xin Tang
Article Number: 77
Published online on: 29 January 2026

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Spatial metabolomics: A new tool for unravelling the metabolic disorders and heterogeneity in diabetic kidney disease (Review)

Hanfei Li, Yuxi Li, Bo Zhang, Wenhao Cheng, Guowei Ma, Jin Rong, Shiru Duan, Di Feng, Tingting Zhao
Article Number: 76
Published online on: 29 January 2026

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Research progress in single‑cell omics technologies for kidney disease (Review)

Jia Xu, Ziwei Chen, Shengyao Li, Xiaoya Wang, Ming Chen
Article Number: 111
Published online on: 03 March 2026

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CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review)

Xiuping Lai, Yan Yan, Lu Sun, Zili Lei, Yanhong Yang
Article Number: 110
Published online on: 03 March 2026

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Article Number: 109
Published online on: 03 March 2026

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Article Number: 108
Published online on: 02 March 2026

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Published online on: 02 March 2026

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[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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