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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2003 Volume 12 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Delivery of recombinant adeno-associated virus by jet injection

Olga Janouskova, Thomas Nellessen, Jitka Stokrova, Pavel Jinoch, Michal Smahel
Pages: 687-691
Published online on: 01 November 2003

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Article

E-cadherin-dependent intercellular adhesion enhances chemoresistance

Tomoaki Nakamura, Yasushi Kato, Hidenori Fuji, Tetsuya Horiuchi, Yukio Chiba, Kuniyoshi Tanaka
Pages: 693-700
Published online on: 01 November 2003

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Article

Treatment of ulcerative colitis patients by long-term administration of germinated barley foodstuff: Multi-center open trial

Osamu Kanauchi, Keiichi Mitsuyama, Terasu Homma, Kazuya Takahama, Yoshihide Fujiyama, Akira Andoh, Yoshio Araki, Toshihiro Suga, Toshifumi Hibi, Makoto Naganuma, Hitoshi Asakura, Hiroshi Nakano, Takashi Shimoyama, Nobuyuki Hida, Ken Haruma, Hideki Koga, Michio Sata, Nobuo Tomiyasu, Atsushi Toyonaga, Masanobu Fukuda, Atsushi Kojima, Tadao Bamba
Pages: 701-704
Published online on: 01 November 2003

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Article

Overexpression of X-linked inhibitor of apoptosis in human hepatocellular carcinoma

Katsuya Shiraki, Kazushi Sugimoto, Yutaka Yamanaka, Yumi Yamaguchi, Yukiko Saitou, Keiichi Ito, Norihiko Yamamoto, Takenari Yamanaka, Katsuhiko Fujikawa, Kazumoto Murata, Takeshi Nakano
Pages: 705-708
Published online on: 01 November 2003

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Article

Overexpression of cyclooxygenase-2 protein and its relationship to apoptosis in cervical carcinoma treated with neoadjuvant chemotherapy

Nobutaka Nagai, Xiurong Tian, Keiji Mukai, Eiji Hirata, Tomoyo Kusuda, Yuko Shiroyama, Kazushi Shigemasa, Koso Ohama
Pages: 709-714
Published online on: 01 November 2003

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Article

Differential expression of homing receptor CD103 on lamina propria lymphocytes and association of CD103 with epithelial adhesion molecules in inflammatory bowel disease

Nobuhide Oshitani, Kenji Watanabe, Kiyoshi Maeda, Yasuhiro Fujiwara, Kazuhide Higuchi, Takayuki Matsumoto, Tetsuo Arakawa
Pages: 715-719
Published online on: 01 November 2003

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Article

N-3 fatty acid-rich diet prevents early response of interleukin-6 elevation in trinitrobenzene sulfonic acid-induced enteritis

Akira Andoh, Tomoyuki Tsujikawa, Izumi Ishizuka, Yoshio Araki, Masaya Sasaki, Shigeki Koyama, Yoshihide Fujiyama
Pages: 721-725
Published online on: 01 November 2003

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Article

11q23-24 loss is associated with chromosomal instability in endometrial cancer

Keiko Kawasaki, Yutaka Suehiro, Kenji Umayahara, Hitoshi Morioka, Takehisa Ito, Toshiaki Saito, Naoki Tsukamoto, Norihiro Sugino, Hiroshi Kato, Kohsuke Sasaki
Pages: 727-731
Published online on: 01 November 2003

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Article

Induction of apoptosis by Se-MSC in U937 human leukemia cells through release of cytochrome c and activation of caspases and PKC-δ: mutual regulation between caspases and PKC-δ via a positive feedback mechanism

Byeong-Churl Jang, Eun-Seok Choi, Ki-Jo Im, Won-Ki Baek, Taek Kyu Kwon, Min-Ho Suh, Sang-Pyo Kim, Jong-Wook Park, Seong-Il Suh
Pages: 733-739
Published online on: 01 November 2003

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Article

Mechanism of thermotolerance induction by split-dose hyperthermia in Deinococcus radiodurans DNA repair deficient mutants

Kazuki Harada, Mami Ando, Tomoko Fujimura-Ito, Mika Kasahara-Imamura, Yoshihiko Sako, Aritsune Uchida, Yuzaburo Ishida, Hajime Kadota, Takeo Ohnishi, Bevan E.B. Moseley
Pages: 741-747
Published online on: 01 November 2003

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Article

Genotypes of CCR2 and CCR5 chemokine receptors in human myasthenia gravis

Xiaoyan Zhao, Baback Gharizadeh, Peter Hjelmström, Ritva Pirskanen, Pål Nyrén, Ann-Kari Lefvert, Mehran Ghaderi
Pages: 749-753
Published online on: 01 November 2003

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Article

Preventive effect of zinc acexamate administration in streptozotocin-diabetic rats: Restoration of bone loss

Masayoshi Yamaguchi, Satoshi Uchiyama
Pages: 755-761
Published online on: 01 November 2003

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Article

Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-3 (E-NPP3/CD203c/PD-Iβ/B10/gp130RB13-6) in human colon carcinoma

Yoshihiko Yano, Yoshitake Hayashi, Kimihiko Sano, Hiroshi Shinmaru, Yoshikazu Kuroda, Hiroshi Yokozaki, Seitetsu Yoon, Masato Kasuga
Pages: 763-766
Published online on: 01 November 2003

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Article

RB1CC1 suppresses cell cycle progression through RB1 expression in human neoplastic cells

Keiichi Kontani, Tokuhiro Chano, Yoshitomo Ozaki, Noriaki Tezuka, Satoru Sawai, Shozo Fujino, Yukikazu Saeki, Hidetoshi Okabe
Pages: 767-769
Published online on: 01 November 2003

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Article

Molecular detection of free cancer cells in pleural lavage fluid from esophageal cancer patients

Shoji Natsugoe, Koki Tokuda, Masataka Matsumoto, Hiroshi Okumura, Akihiro Nakajo, Hiroyuki Takatori, Hiroshi Nakashima, Sumiya Ishigami, Sonshin Takao, Takashi Aikou
Pages: 771-775
Published online on: 01 November 2003

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Article

Ghrelin clearance is reduced at the late stage of polymicrobial sepsis

Rongqian Wu, Mian Zhou, Xiaoxuan Cui, H. Hank Simms, Ping Wang
Pages: 777-781
Published online on: 01 November 2003

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Article

Identification and expression analysis of a novel splice variant of human Sprouty1 gene

Liu Wang, Chaoneng Ji, Hai Wu, Jian Xu, Qihan Wu, Jianfeng Dai, Gang Yin, Xin Ye, Shaohua Gu, Yi Xie, Yumin Mao
Pages: 783-787
Published online on: 01 November 2003

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Article

Experimental therapy of HPV16 induced tumors with IL12 expressed by recombinant vaccinia virus in mice

Sárka Nemeckova, Vojtech Sroller, Petr Hainz, Jitka Krystofova, Michal Smahel, L. Kutinova
Pages: 789-796
Published online on: 01 November 2003

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Article

Human soluble tumor-associated antigens promote the suppression of rat mammary tumors by 5-fluorouracil and stimulate the functional activity of immune organs: Experimental and morphological studies

George Kossoy, Herzl Ben-Hur, Ilana Avinoach, Asher Alhayany, David F. Shneider, Itshak Zusman
Pages: 797-801
Published online on: 01 November 2003

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Article

Differential effects of estradiol and raloxifene on collagen biosynthesis in cultured human skin fibroblasts

Arkadiusz Surazynski, Katarzyna Jarzabek, Jozef Haczynski, Piotr Laudanski, Jerzy Palka, Slawomir Wolczynski
Pages: 803-809
Published online on: 01 November 2003

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Review

WNT2 and human gastrointestinal cancer (Review)

Masaru Katoh
Pages: 811-816
Published online on: 01 November 2003

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Article

Identification and characterization of TRIP8 gene in silico

Masuko Katoh, Masaru Katoh
Pages: 817-821
Published online on: 01 November 2003

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Journal Cover
May-2026 Volume 57 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Macrophage SH3 domain‑containing GRB2‑like protein B1 is required for Rab7‑mediated mitophagy in inflammation during sea water drowning acute lung injury

Hongjuan Ning, Jingyu Deng, Yongheng Gao, Wei Zhang, Jian Chen, Xian Guo, Faguang Jin
Article Number: 138
Published online on: 24 March 2026

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Deferoxamine mitigates neuronal loss following spinal cord injury via ferroptosis inhibition and Nrf2/HO‑1 pathway activation

Ziqian Ma, Xinwei Zhang, Tao Liu, Yan Zhang, Guanghao Li, Xin Yuan, Benqiang Tang, Hangyi Zhao, Liang Liu, Xueming Chen
Article Number: 137
Published online on: 23 March 2026

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Review Open Access

USP10 deubiquitinase: Physiological function, diseases and therapeutic target (Review)

Linlin Zhang, Huajing Sun, Zifan Wang, Zhimei Wang, Qiang Mu, Yukun Liu
Article Number: 136
Published online on: 23 March 2026

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Article Open Access

Siglec‑15 dysregulation and its therapeutic implications in new‑onset type 1 diabetes 

Heming Guo, Yunwen Tao, Sicheng Li, Ying Gu, Yiting Huang, Chen Fang, Ji Hu
Article Number: 135
Published online on: 20 March 2026

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Article Open Access

ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing

Yan Zhao, Yuankai Zhang, Tian Lei, Shangqing Zhang, Kai Nan, Xin Zhang, Li-Hong Fan
Article Number: 134
Published online on: 19 March 2026

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Review Open Access

Targeting pyroptosis in renal fibrosis: From molecular mechanisms to therapeutic horizons (Review)

Yihuai Tian, Quwu Mushuo, Hui Fan, Hongwei Su, Jianchun Li, Qiong Zhang
Article Number: 133
Published online on: 19 March 2026

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Expression of Concern Open Access

[Expression of Concern] Fasudil, a Rho‑associated protein kinase inhibitor, attenuates retinal ischemia and reperfusion injury in rats

Haishan Song, Dianwen Gao
Article Number: 132
Published online on: 18 March 2026

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Review Open Access

Epigenetic regulation in a high-sugar environment (Review)

Huili Zhou, Xinhe Lv, Yu Liang, Dehai Yu, Wanning Wang
Article Number: 131
Published online on: 17 March 2026

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Review Open Access

The roles and heterogeneity of CD8+ T cells in inflammatory bowel disease: A narrative review of insights from single‑cell transcriptomics (Review)

Rui Zhong, Jing Guo, Wujie Ye, Zhihui Deng, Huangan Wu, Qin Qi, Guona Li, Lu Zhu, Yan Huang, Luyi Wu
Article Number: 130
Published online on: 17 March 2026

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Review Open Access

Mechanism of action and clinical application of autophagy in multiple sclerosis (Review)

Dongmei Wang, Qizhi Fu, Ying Zhao, Guangda Li, Yongjie Bai, Yang Yang, Hongna Song, Mingwei Wang, Hua Fan
Article Number: 129
Published online on: 17 March 2026

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Expression of Concern Open Access

[Expression of Concern] Insulin‑dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation

Mamiko Hie, Natsumi Iitsuka, Tomoyo Otsuka, Ikuyo Tsukamoto
Article Number: 128
Published online on: 16 March 2026

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Mechanotransduction and its impact on regenerative medicine in orthopedic rehabilitation (Review)

Baohui Wang, Xueqin Zeng, Huajian Liu, Liang Li, Tao Lei, Yafeng Li, Qing Fang, Yi Cao, Bo Dong
Article Number: 127
Published online on: 13 March 2026

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Article Open Access

4‑Acetylantrocamol LT3 suppresses colorectal cancer growth and metastasis via PI3K/AKT and MAPK pathway modulation

Kuen-Tze Lin, Yu-Chieh Hsieh, Pi-Kai Chang, Chih-Wei Lai, Shih-Yu Lee, I-Chuan Yen
Article Number: 126
Published online on: 13 March 2026

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Roles of ubiquitin‑specific peptidase 22 in cellular fate: From embryonic survival to tissue repair, inflammation and metabolism (Review)

Jia-Nan Xiang, Chen-Yang Zhou, Yu-Di Zhao, Xiao Xu, Sun-Bin Ling
Article Number: 125
Published online on: 12 March 2026

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m6A in adipose tissue inflammation: A novel regulator of obesity and metabolic diseases (Review)

Xiaoting Yang, Xiaodan Wang, Haojun Tang, Shuangxi Tu, Kai Yin, Xiao Zhu
Article Number: 124
Published online on: 12 March 2026

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Expression of Concern Open Access

[Expression of Concern] Visfatin/PBEF/Nampt induces EMMPRIN and MMP‑9 production in macrophages via the NAMPT‑MAPK (p38, ERK1/2)‑NF‑κB signaling pathway

Yuqi Fan, Shu Meng, Yue Wang, Jiatian Cao, Changqian Wang
Article Number: 123
Published online on: 12 March 2026

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Article Open Access

IL‑37/IL‑1R8 blocks keratinocyte acantholysis via suppressing ADAM17/EGFR

Fengxia Hu, Wenjing Chen, Qian Wang, Xiaoyu Zhang, Fuyang Xiao, Jinying Zhang, Junqin Liang
Article Number: 122
Published online on: 12 March 2026

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Reactive oxygen species in fetal growth restriction mechanisms and therapeutic directions (Review)

Di Cheng, Songbin Yang, Cuilan Wang, Kefeng Fan, Fengchun Gao, Qian Sun
Article Number: 121
Published online on: 12 March 2026

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Research progress on the molecular mechanisms of tanshinone IIA in the treatment of cardiovascular and cerebrovascular diseases (Review)

Wen Pei, Ping Lu, Chenhuan Ding, Ying Li, Yong Li
Article Number: 120
Published online on: 12 March 2026

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Ferritin in ferroptosis: Implications for neurodegenerative diseases (Review)

Wenjing Chen, Heng Tian, Ran Wei, Xiaomei Chen, Yiwen Jia
Article Number: 119
Published online on: 12 March 2026

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Correction Open Access

[Corrigendum] Ursolic acid protects against cisplatin‑induced ototoxicity by inhibiting oxidative stress and TRPV1‑mediated Ca2+‑signaling  

Yang Di, Tao Xu, Yuan Tian, Tingting Ma, Donghao Qu, Yan Wang, Yuhan Lin, Dongyan Bao, Li Yu, Shuangyue Liu, Aimei Wang
Article Number: 118
Published online on: 09 March 2026

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Article Open Access

HELLS inhibits autophagy‑dependent ferroptosis in nasopharyngeal carcinoma by modulating the Nrf2/HO‑1/GPX4 pathway

Chengxun Jin, Jinqiu Li, Siqi Han, Chaoluomeng Bai, Jingpu Yang, Zonggui Wang
Article Number: 117
Published online on: 09 March 2026

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Expression of Concern Open Access

[Expression of Concern] Inhibitory effect of curcumin on angiogenesis in ectopic endometrium of rats with experimental endometriosis

Ying Zhang, Hong Cao, Yue-Yue Hu, Hua Wang, Chang-Jun Zhang
Article Number: 116
Published online on: 09 March 2026

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Article Open Access

Propofol upregulates MFG‑E8 in BV2 cells to inhibit pyroptosis mediated by the NF‑κB/NLRP3 pathway, thereby ameliorating ischemic‑reperfusion neuronal injury

Shewei Guo, Yingwei Zhen, Guosheng Zhou, Zhihua Zhao
Article Number: 115
Published online on: 05 March 2026

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Article Open Access

Exosomal circ0000549 promotes MNNG‑induced gastric cancer through miR‑15b‑5p/KIF1B

Zhaofeng Liang, Zihan Gao, Yue Zhang, Jiajia Song, Hui Qian, Xuezhong Xu
Article Number: 114
Published online on: 04 March 2026

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Expression of Concern Open Access

[Expression of Concern] Syringin prevents cardiac hypertrophy induced by pressure overload through the attenuation of autophagy  

Fangfang Li, Ning Zhang, Qingqing Wu, Yuan Yuan, Zheng Yang, Mengqiao Zhou, Jinxiu Zhu, Qizhu Tang
Article Number: 113
Published online on: 04 March 2026

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Review Open Access

Treatment of pulmonary fibrosis: From disease mechanisms to future novel therapies (Review)

Sen Lu, Yunfei Liu, Xiaohua Li, Qipeng Yao
Article Number: 112
Published online on: 03 March 2026

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Review Open Access

Research progress in single‑cell omics technologies for kidney disease (Review)

Jia Xu, Ziwei Chen, Shengyao Li, Xiaoya Wang, Ming Chen
Article Number: 111
Published online on: 03 March 2026

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Review Open Access

CLDN7: Epithelial gatekeeper from physiology to pathology‑roles in cancer and epithelial‑related diseases (Review)

Xiuping Lai, Yan Yan, Lu Sun, Zili Lei, Yanhong Yang
Article Number: 110
Published online on: 03 March 2026

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Review Open Access

Dynamic regulation and targeted intervention of neutrophils in hepatic ischemia‑reperfusion injury (Review)

Sen Lu, Jiale Tong, Jing Jiang, Qin Zhang, Youjin Huang
Article Number: 109
Published online on: 03 March 2026

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Review Open Access

The dual role of the crosstalk between autophagy and ferroptosis in lung cancer treatment: Advances in mechanisms and therapeutic strategies (Review)

Yingying Zhang, Ruxin Shen
Article Number: 108
Published online on: 02 March 2026

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Mechanistic insights into inflammatory cytokines in adenomyosis‑induced infertility (Review)

Bojiao Yang, Feng Li, Guimao Cao, Mingtu Nuo, Yaxin Shi, Zilu Wang, Jing Jia, Wei Shi, Zhiyong Liu
Article Number: 107
Published online on: 02 March 2026

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Correction Open Access

[Corrigendum] Astragaloside IV promotes the proliferation and migration of osteoblast‑like cells through the hedgehog signaling pathway

Li-Hua Guo, Yu Cao, Run-Tao Zhuang, Yan Han, Jun Li
Article Number: 106
Published online on: 02 March 2026

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Journal Cover
June-2026 Volume 57 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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