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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November 2003 Volume 12 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Delivery of recombinant adeno-associated virus by jet injection

Olga Janouskova, Thomas Nellessen, Jitka Stokrova, Pavel Jinoch, Michal Smahel
Pages: 687-691
Published online on: 01 November 2003

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Article

E-cadherin-dependent intercellular adhesion enhances chemoresistance

Tomoaki Nakamura, Yasushi Kato, Hidenori Fuji, Tetsuya Horiuchi, Yukio Chiba, Kuniyoshi Tanaka
Pages: 693-700
Published online on: 01 November 2003

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Article

Treatment of ulcerative colitis patients by long-term administration of germinated barley foodstuff: Multi-center open trial

Osamu Kanauchi, Keiichi Mitsuyama, Terasu Homma, Kazuya Takahama, Yoshihide Fujiyama, Akira Andoh, Yoshio Araki, Toshihiro Suga, Toshifumi Hibi, Makoto Naganuma, Hitoshi Asakura, Hiroshi Nakano, Takashi Shimoyama, Nobuyuki Hida, Ken Haruma, Hideki Koga, Michio Sata, Nobuo Tomiyasu, Atsushi Toyonaga, Masanobu Fukuda, Atsushi Kojima, Tadao Bamba
Pages: 701-704
Published online on: 01 November 2003

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Article

Overexpression of X-linked inhibitor of apoptosis in human hepatocellular carcinoma

Katsuya Shiraki, Kazushi Sugimoto, Yutaka Yamanaka, Yumi Yamaguchi, Yukiko Saitou, Keiichi Ito, Norihiko Yamamoto, Takenari Yamanaka, Katsuhiko Fujikawa, Kazumoto Murata, Takeshi Nakano
Pages: 705-708
Published online on: 01 November 2003

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Article

Overexpression of cyclooxygenase-2 protein and its relationship to apoptosis in cervical carcinoma treated with neoadjuvant chemotherapy

Nobutaka Nagai, Xiurong Tian, Keiji Mukai, Eiji Hirata, Tomoyo Kusuda, Yuko Shiroyama, Kazushi Shigemasa, Koso Ohama
Pages: 709-714
Published online on: 01 November 2003

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Article

Differential expression of homing receptor CD103 on lamina propria lymphocytes and association of CD103 with epithelial adhesion molecules in inflammatory bowel disease

Nobuhide Oshitani, Kenji Watanabe, Kiyoshi Maeda, Yasuhiro Fujiwara, Kazuhide Higuchi, Takayuki Matsumoto, Tetsuo Arakawa
Pages: 715-719
Published online on: 01 November 2003

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Article

N-3 fatty acid-rich diet prevents early response of interleukin-6 elevation in trinitrobenzene sulfonic acid-induced enteritis

Akira Andoh, Tomoyuki Tsujikawa, Izumi Ishizuka, Yoshio Araki, Masaya Sasaki, Shigeki Koyama, Yoshihide Fujiyama
Pages: 721-725
Published online on: 01 November 2003

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Article

11q23-24 loss is associated with chromosomal instability in endometrial cancer

Keiko Kawasaki, Yutaka Suehiro, Kenji Umayahara, Hitoshi Morioka, Takehisa Ito, Toshiaki Saito, Naoki Tsukamoto, Norihiro Sugino, Hiroshi Kato, Kohsuke Sasaki
Pages: 727-731
Published online on: 01 November 2003

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Article

Induction of apoptosis by Se-MSC in U937 human leukemia cells through release of cytochrome c and activation of caspases and PKC-δ: mutual regulation between caspases and PKC-δ via a positive feedback mechanism

Byeong-Churl Jang, Eun-Seok Choi, Ki-Jo Im, Won-Ki Baek, Taek Kyu Kwon, Min-Ho Suh, Sang-Pyo Kim, Jong-Wook Park, Seong-Il Suh
Pages: 733-739
Published online on: 01 November 2003

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Article

Mechanism of thermotolerance induction by split-dose hyperthermia in Deinococcus radiodurans DNA repair deficient mutants

Kazuki Harada, Mami Ando, Tomoko Fujimura-Ito, Mika Kasahara-Imamura, Yoshihiko Sako, Aritsune Uchida, Yuzaburo Ishida, Hajime Kadota, Takeo Ohnishi, Bevan E.B. Moseley
Pages: 741-747
Published online on: 01 November 2003

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Article

Genotypes of CCR2 and CCR5 chemokine receptors in human myasthenia gravis

Xiaoyan Zhao, Baback Gharizadeh, Peter Hjelmström, Ritva Pirskanen, Pål Nyrén, Ann-Kari Lefvert, Mehran Ghaderi
Pages: 749-753
Published online on: 01 November 2003

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Article

Preventive effect of zinc acexamate administration in streptozotocin-diabetic rats: Restoration of bone loss

Masayoshi Yamaguchi, Satoshi Uchiyama
Pages: 755-761
Published online on: 01 November 2003

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Article

Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-3 (E-NPP3/CD203c/PD-Iβ/B10/gp130RB13-6) in human colon carcinoma

Yoshihiko Yano, Yoshitake Hayashi, Kimihiko Sano, Hiroshi Shinmaru, Yoshikazu Kuroda, Hiroshi Yokozaki, Seitetsu Yoon, Masato Kasuga
Pages: 763-766
Published online on: 01 November 2003

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Article

RB1CC1 suppresses cell cycle progression through RB1 expression in human neoplastic cells

Keiichi Kontani, Tokuhiro Chano, Yoshitomo Ozaki, Noriaki Tezuka, Satoru Sawai, Shozo Fujino, Yukikazu Saeki, Hidetoshi Okabe
Pages: 767-769
Published online on: 01 November 2003

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Article

Molecular detection of free cancer cells in pleural lavage fluid from esophageal cancer patients

Shoji Natsugoe, Koki Tokuda, Masataka Matsumoto, Hiroshi Okumura, Akihiro Nakajo, Hiroyuki Takatori, Hiroshi Nakashima, Sumiya Ishigami, Sonshin Takao, Takashi Aikou
Pages: 771-775
Published online on: 01 November 2003

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Article

Ghrelin clearance is reduced at the late stage of polymicrobial sepsis

Rongqian Wu, Mian Zhou, Xiaoxuan Cui, H. Hank Simms, Ping Wang
Pages: 777-781
Published online on: 01 November 2003

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Article

Identification and expression analysis of a novel splice variant of human Sprouty1 gene

Liu Wang, Chaoneng Ji, Hai Wu, Jian Xu, Qihan Wu, Jianfeng Dai, Gang Yin, Xin Ye, Shaohua Gu, Yi Xie, Yumin Mao
Pages: 783-787
Published online on: 01 November 2003

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Article

Experimental therapy of HPV16 induced tumors with IL12 expressed by recombinant vaccinia virus in mice

Sárka Nemeckova, Vojtech Sroller, Petr Hainz, Jitka Krystofova, Michal Smahel, L. Kutinova
Pages: 789-796
Published online on: 01 November 2003

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Article

Human soluble tumor-associated antigens promote the suppression of rat mammary tumors by 5-fluorouracil and stimulate the functional activity of immune organs: Experimental and morphological studies

George Kossoy, Herzl Ben-Hur, Ilana Avinoach, Asher Alhayany, David F. Shneider, Itshak Zusman
Pages: 797-801
Published online on: 01 November 2003

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Article

Differential effects of estradiol and raloxifene on collagen biosynthesis in cultured human skin fibroblasts

Arkadiusz Surazynski, Katarzyna Jarzabek, Jozef Haczynski, Piotr Laudanski, Jerzy Palka, Slawomir Wolczynski
Pages: 803-809
Published online on: 01 November 2003

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Review

WNT2 and human gastrointestinal cancer (Review)

Masaru Katoh
Pages: 811-816
Published online on: 01 November 2003

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Article

Identification and characterization of TRIP8 gene in silico

Masuko Katoh, Masaru Katoh
Pages: 817-821
Published online on: 01 November 2003

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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Article Open Access

MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Article Open Access

Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Article Open Access

Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Article Open Access

Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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Article Open Access

ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Review Open Access

Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

FGF4 alleviates the lung cell damage caused by high glucose via AMPK‑PGC‑1 signaling axis in vitro and in vivo

Qiujuan Fu, Yongfang Ou, Qin Wu, Jue Gong, Feixia Li, Tuxing Wang, Zhitai Lin, Kejie Huang, Jianlong Xie
Article Number: 39
Published online on: 05 December 2025

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STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Article Number: 33
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Article Number: 32
Published online on: 01 December 2025

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[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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