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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2012 Volume 30 Issue 6

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review

Elucidating the regulation of T cell subsets (Review)

Yasuko Kitagishi, Mayumi Kobayashi, Yurie Yamashina, Satoru Matsuda
Pages: 1255-1260
Published online on: 09 October 2012

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Review

GPR40: A therapeutic target for mediating insulin secretion (Review)

Xiao-Tao Feng, Jing Leng, Zhen Xie, Shuang-Lei Li, Wei Zhao, Qian-Li Tang
Pages: 1261-1266
Published online on: 26 September 2012

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Article Open Access

Polypeptide N-acetylgalactosaminyltransferase 2 regulates cellular metastasis-associated behavior in gastric cancer

Dong Hua, Li Shen, Lan Xu, Zhi Jiang, Yinghui Zhou, Aihuan Yue, Shitao Zou, Zhihong Cheng, Shiliang Wu
Pages: 1267-1274
Published online on: 18 September 2012

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Article Open Access

Possible role of transforming growth factor-β1 and vascular endothelial growth factor in Fabry disease nephropathy

Mi Hee Lee, Eun Nam Choi, Yeo Jin Jeon, Sung-Chul Jung
Pages: 1275-1280
Published online on: 24 September 2012

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Article Open Access

RING-finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoid arthritis

Naoko Yagishita, Satoko Aratani, Craig Leach, Tetsuya Amano, Yoshihisa Yamano, Ko Nakatani, Kusuki Nishioka, Toshihiro Nakajima
Pages: 1281-1286
Published online on: 18 September 2012

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Article Open Access

Identification of KRAP-expressing cells and the functional relevance of KRAP to the subcellular localization of IP3R in the stomach and kidney

Takahiro Fujimoto, Senji Shirasawa
Pages: 1287-1293
Published online on: 17 September 2012

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Article

Restoration of alveolar type II cell function contributes to simvastatin-induced attenuation of lung ischemia-reperfusion injury

Yaqin Wu, Junjie Lv, Dongjie Feng, Feng Jiang, Xiaohu Fan, Zhi Zhang, Rong Yin, Lin Xu
Pages: 1294-1306
Published online on: 16 October 2012

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Article

Arginine inactivates human herpesvirus 2 and inhibits genital herpesvirus infection

Keiko Ikeda, Hisashi Yamasaki, Sawako Minami, Yukiko Suzuki, Kazuko Tsujimoto, Yoshihisa Sekino, Hiroshi Irie, Tsutomu Arakawa, A. Hajime Koyama
Pages: 1307-1312
Published online on: 04 October 2012

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Article

Hyperglycemia suppresses cardiac stem cell homing to peri-infarcted myocardium via regulation of ERK1/2 and p38 MAPK activities

Tonghui She, Xiaoyan Wang, Yaping Gan, Dong Kuang, Junqiu Yue, Juan Ni, Xia Zhao, Guoping Wang
Pages: 1313-1320
Published online on: 11 September 2012

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Article

microRNA-29a suppresses cell proliferation by targeting SPARC in hepatocellular carcinoma

Xu-Chao Zhu, Qiong-Zhu Dong, Xiao-Fei Zhang, Biao Deng, Hu-Liang Jia, Qin-Hai Ye, Lun-Xiu Qin, Xing-Zhong Wu
Pages: 1321-1326
Published online on: 25 September 2012

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Article

Comparative study of the osteogenic differentiation capacity of human bone marrow- and human adipose-derived stem cells under cyclic tensile stretch using quantitative analysis

Yaping Ye, Yu Du, Fengjing Guo, Chen Gong, Kaixiang Yang, Liang Qin
Pages: 1327-1334
Published online on: 07 September 2012

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Article

Prophylactic and therapeutic efficacy of an attenuated Listeria monocytogenes-based vaccine delivering HPV16 E7 in a mouse model

Yanyan Jia, Yuelan Yin, Feifei Duan, Hong Fu, Maozhi Hu, Yunfei Gao, Zhiming Pan, Xinan Jiao
Pages: 1335-1342
Published online on: 20 September 2012

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Article

Construction and characterization of a eukaryotic expression vector for small interfering RNA targeting the NEDD9 gene

Jing-Xia Chang, Hua-Qi Wang, Guo-Qiang Zhao, He-Ying Chu, Guo-Jun Zhang
Pages: 1343-1348
Published online on: 20 September 2012

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Article

Centella asiatica protects against UVB-induced HaCaT keratinocyte damage through microRNA expression changes

In-Sook An, Sungkwan An, Tae-Βoo Choe, Sang-Μo Kang, Jae Ho Lee, In-Chul Park, Young-Woo Jin, Su-Jae Lee, Seunghee Bae
Pages: 1349-1356
Published online on: 15 October 2012

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Article

Inhibitory effect of butein on tumor necrosis factor-α-induced expression of cell adhesion molecules in human lung epithelial cells via inhibition of reactive oxygen species generation, NF-κB activation and Akt phosphorylation

Ji Hoon Jang, Eun Sun Yang, Kyoung-Jin Min, Taeg Kyu Kwon
Pages: 1357-1364
Published online on: 15 October 2012

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Article

Inhibition of cardiac hypertrophy by probiotic-fermented purple sweet potato yogurt in spontaneously hypertensive rat hearts

Pei-Pei Lin, You-Miin Hsieh, Wei-Wen Kuo, Chien-Chung Lin, Fuu-Jen Tsai, Chang-Hai Tsai, Chih-Yang Huang, Cheng-Chih Tsai
Pages: 1365-1375
Published online on: 12 October 2012

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Article

Transient prehypertensive treatment in spontaneously hypertensive rats: A comparison of losartan and amlodipine regarding long-term blood pressure, cardiac and renal protection

Feng Peng, Jinxiu Lin, Liming Lin, Hong Tang
Pages: 1376-1386
Published online on: 09 October 2012

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Article

Significant correlation between the acceleration of platelet aggregation and phosphorylation of HSP27 at Ser-78 in diabetic patients

Haruhiko Tokuda, Kenji Kato, Senji Kasahara, Rie Matsushima-Nishiwaki, Takahiko Mizuno, Seiko Sakakibara, Osamu Kozawa
Pages: 1387-1395
Published online on: 01 October 2012

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Article

Expression of aldosterone synthase and adrenocorticotropic hormone receptor in adrenal incidentalomas from normotensive and hypertensive patients: Distinguishing subclinical or atypical primary aldosteronism from adrenal incidentaloma

C. X. Cao, X. C. Yang, Y. X. Gao, M. Zhuang, K. P. Wang , L. J. Sun, X. S. Wang
Pages: 1396-1402
Published online on: 27 September 2012

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Article

Coxsackievirus and adenovirus receptor promotes antitumor activity of oncolytic adenovirus H101 in esophageal cancer

Junfen Ma, Jimin Zhao, Jing Lu, Yanan Jiang, Hongyan Yang, Pei Li, Mingyao Zhao, Kangdong Liu, Ziming Dong
Pages: 1403-1409
Published online on: 19 September 2012

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Article

Grape seed proanthocyanidins inhibit colon cancer-induced angiogenesis through suppressing the expression of VEGF and Ang1

Shuangsheng Huang, Ninggang Yang, Yuanyuan Liu, Jing Gao, Tao  Huang, Lamei Hu, Jin Zhao, Yongquan Li, Caili Li, Xiaosu Zhang
Pages: 1410-1416
Published online on: 01 October 2012

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Article

MMP-9 inhibition suppresses wear debris-induced inflammatory osteolysis through downregulation of RANK/RANKL in a murine osteolysis model

Desheng Chen, Xianlong Zhang, Yongyuan Guo, Sifeng Shi, Xin Mao, Xiaoyun Pan, Tao Cheng
Pages: 1417-1423
Published online on: 01 October 2012

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Article

Differential expression of PTEN in hepatic tissue and hepatic stellate cells during rat liver fibrosis and its reversal

Libo Zheng, Xiuli Chen, Jinbo Guo, Huicong Sun, Lei Liu, David Q. Shih, Xiaolan Zhang
Pages: 1424-1430
Published online on: 05 October 2012

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Article

Sodium butyrate restores ASC expression and induces apoptosis in LS174T cells

Shuai Zhang, Jingqiao Bai, Shuangyi Ren, Ran Wang, Li Zhang, Yunfei Zuo
Pages: 1431-1437
Published online on: 15 October 2012

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Article

Mutations in different regions of the genome of hepatitis C virus genotype 1b and association with response to interferon therapy

Lin Zhang, Feng Han, Dan Zhang, Xiao-Guang Dou
Pages: 1438-1442
Published online on: 15 October 2012

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Article

HBV promotes the proliferation of hepatic stellate cells via the PDGF-B/PDGFR-β signaling pathway in vitro

Qixuan Bai, Jing An, Xiaoning Wu, Hong You, Hong Ma, Tianhui Liu, Na Gao, Jidong Jia
Pages: 1443-1450
Published online on: 04 October 2012

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Article

Sphingosine-1-phosphate inhibits interleukin-1β-induced inflammation in human articular chondrocytes

Myung-Hee Moon, Jae-Kyo Jeong, You-Jin Lee, Jae-Won Seol, Sang-Youel Park
Pages: 1451-1458
Published online on: 19 September 2012

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Article

Involvement of the WNT and FGF signaling pathways in non-isolated anorectal malformations: Sequencing analysis of WNT3A, WNT5A, WNT11, DACT1, FGF10, FGFR2 and the T gene

Markus Draaken, Wiebke Prins, Claudia Zeidler, Alina Hilger, Sadaf S. Mughal, Jeanette Latus, Thomas M. Boemers, Dominik Schmidt, Eberhard Schmiedeke, Nicole Spychalski, Enrika Bartels, Markus M. Nöthen, Heiko Reutter, Michael Ludwig
Pages: 1459-1464
Published online on: 07 September 2012

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Article

Hexane extract from Uncaria sinensis exhibits anti-apoptotic properties against glutamate-induced neurotoxicity in primary cultured cortical neurons

Ji-Yeon Jang, Ha-Neui Kim, Yu-Ri Kim, Jin-Woo Hong, Young-Whan Choi, Yung-Hyun Choi, Hwa-Kyoung Shin, Byung-Tae Choi
Pages: 1465-1472
Published online on: 19 September 2012

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Article

Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1

Andreea M. Bujor, Paul Haines, Cristina Padilla, Romy B. Christmann, Monica Junie, Percival D. Sampaio-Barros, Robert Lafyatis, Maria Trojanowska
Pages: 1473-1480
Published online on: 05 October 2012

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Article

Suppression of lung cancer metastasis-related protein 1 promotes apoptosis in lung cancer cells

Yang Xu, Chunsun Li, Qing Tian, Yanqin Li, Zhen Yang, Zhixin Liang, Liangan Chen
Pages: 1481-1486
Published online on: 16 October 2012

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Article

AMP-activated protein kinase inhibitor decreases prostaglandin F2α-stimulated interleukin-6 synthesis through p38 MAP kinase in osteoblasts

Akira Kondo, Takanobu Otsuka, Kenji Kato, Hideo Natsume, Gen Kuroyanagi, Jun Mizutani, Yoshiki Ito, Rie Matsushima-Nishiwaki, Osamu Kozawa, Haruhiko Tokuda
Pages: 1487-1492
Published online on: 15 October 2012

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Article

Regulation of mammalian MOR-1 gene expression after chronic treatment with morphine

Rose V. Prenus, Ebens Luscar, Zhi-Ping Zhu, Ramesh B. Badisa, Carl B. Goodman
Pages: 1493-1497
Published online on: 19 September 2012

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Article

Impairment of the retinoic acid-inducible gene-I-IFN-β signaling pathway in chronic hepatitis B virus infection

Gangde Zhao, Baoyan An, Huijuan Zhou, Hui Wang, Yumin Xu, Xiaogang Xiang, Zhixia Dong, Fangmei An, Dongshan Yu, Weijing Wang, Shisan Bao, Qing Xie
Pages: 1498-1504
Published online on: 19 September 2012

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Article

Gemcitabine reactivates epigenetically silenced genes and functions as a DNA methyltransferase inhibitor

Steven G. Gray, Anne-Marie Baird, Fardod O'Kelly, Georgios Nikolaidis, Malin Almgren, Armelle Meunier, Eilis Dockry, Donal Hollywood, Tomas J. Ekström, Antoinette S. Perry, Kenneth J. O'Byrne
Pages: 1505-1511
Published online on: 21 September 2012

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Article

Bambusae Caulis in Taeniam modulates neuroprotective and anti-neuroinflammatory effects in hippocampal and microglial cells via HO-1- and Nrf-2-mediated pathways

Hye Won Eom, Sun Young Park, Young Hun Kim, Su Jin Seong, Mei Ling Jin, Eun Yeon Ryu, Min Ju Kim, Sang Joon Lee
Pages: 1512-1520
Published online on: 18 September 2012

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Article

Proteomic analysis of changes in protein expression in serum from animals exposed to paraquat

Yong-Sik Kim, Hana Jung, Hyo-Wook Gil, Sae-Yong Hong, Ho-Yeon Song
Pages: 1521-1527
Published online on: 27 September 2012

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Article

Short- and long-term effects of various Citrullus colocynthis seed extracts in normal and streptozotocin-induced diabetic rats

Nabila Benariba, Rabeh Djaziri, Bouchra Hanane Zerriouh, Wafaa Bellakhdar, Emeline Hupkens, Zahia Boucherit, Willy J. Malaisse
Pages: 1528-1536
Published online on: 18 September 2012

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Article

Stromal cell-derived factor-1α and macrophage migration-inhibitory factor induce metastatic behavior in CXCR4-expressing colon cancer cells

Han-Na Shin, Hyun-Hye Moon, Ja-Lok Ku
Pages: 1537-1543
Published online on: 25 September 2012

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Journal Cover
October-2026 Volume 58 Issue 4

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Role of adipocytes and their derived extracellular vesicles in the progression, diagnosis and treatment of liver diseases (Review)

Kangrong Li, Muhammad Zubair, Yongmin Yan, Jiahao Xu
Article Number: 293
Published online on: 20 August 2026

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Correction Open Access

[Corrigendum] EBM84 attenuates airway inflammation and mucus hypersecretion in an ovalbumin‑induced murine model of asthma

In Sik Shin, Mee Young Lee, Woo Young Jeon, Na Ra Shin, Chang Seob Seo, Hyekyung Ha
Article Number: 292
Published online on: 20 August 2026

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Review Open Access

Decoding fibroblast activation: Transcriptional networks in hepatic stellate cells and across fibrotic organs (Review)

Denita Charoenthanakitkul, Chaiyaboot Ariyachet
Article Number: 291
Published online on: 20 August 2026

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Review Open Access

Inflammatory bowel disease treatment: Mechanisms to clinical translation (Review)

Siqi Tang, Guoyou Gou, Youjia Liu, Fang Wang, Feihong Shu, Ya Deng, Ting Zhang, Jingyu Xu, Rui Xie
Article Number: 290
Published online on: 18 August 2026

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Review Open Access

Redox biology in PCOS: Biomarkers, mechanistic networks, and targeted interventions (Review)

Yuena Qiu, Xiaojing Guo, Jie An
Article Number: 289
Published online on: 18 August 2026

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Review Open Access

Glucose metabolism in osteoporosis: A potential therapeutic target (Review)

Shengyao Peng, Zhuo Yao, Junzhe Guo, Chi Zhang, Keda Yang, Lin Tao
Article Number: 288
Published online on: 17 August 2026

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Retraction Open Access

[Retracted] Engulfment of platelets delays endothelial cell aging via girdin and its phosphorylation

Yong Lan, Yongjun Li, Dajun Li, Peng Li, Jiyang Wang, Yongpeng Diao, Guodong Ye, Yangfang Li
Article Number: 287
Published online on: 17 August 2026

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Article Open Access

α‑Cyperone targets the PAK1‑JNK/NF‑κB axis to modulate dendritic cells maturation and Th2/Th9 differentiation in an asthma model

Hang Hu, Xing Wang, Linlin Guo, Ziling Zeng, Hongmei Tang, Yun Zhang, Jiayao Duan, Kaijin Wang
Article Number: 286
Published online on: 14 August 2026

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Article Open Access

Early high‑frequency spinal cord stimulation modulates the ROS/p38 MAPK/NF‑κB and CXCL10/CXCR3 pathways to alleviate neuropathic pain and promote spinal cord injury repair

Sitong Su, Tao Liu, Honghui Lei, Yang Yu, Caizhi Ma, Xinglang Wang, Haoyuan Chen, Zebin Huang, Meiling Cheng, Tongtong Qian, Fangyong Wang
Article Number: 285
Published online on: 13 August 2026

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Review Open Access

Shared mechanisms of musculoskeletal dysfunction in type 2 diabetes mellitus: Insights into future therapeutic directions (Review)

Zhenhong He, Hanyu Li, Yuhan Luo, Yingying Yu, Siyu Li, Tao Zhang, Dingsu Bao
Article Number: 284
Published online on: 12 August 2026

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Expression of Concern Open Access

[Expression of Concern] Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway

Xinying Zhang, Li Zhang, Zhe Chen, Siwei Li, Bingbing Che, Ningning Wang, Junting Chen, Changqing Xu, Can Wei
Article Number: 283
Published online on: 12 August 2026

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Article Open Access

G protein‑coupled receptor kinase 4 governs early kidney development via STAT3 and Nhe3a

Linh Anna Trúc Vu, Julian Gerhards, Lars D. Maerz, Martin D. Burkhalter, Melanie Philipp
Article Number: 282
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Resistant starch prevents tumorigenesis of dimethylhydrazine‑induced colon tumors via regulation of an ER stress‑mediated mitochondrial apoptosis pathway  

Qiuyu Wang, Peng Wang, Zhigang Xiao
Article Number: 281
Published online on: 10 August 2026

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Review Open Access

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review)

Ziwei Chen, Jiaqi Wu, Wenxi Liu, Jie Tan, Xiaochun Peng, Yanhua Zhang, Gai Liang
Article Number: 280
Published online on: 05 August 2026

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Review Open Access

Decoding miRNA‑146a: Mechanisms of action in cardiovascular diseases and endocrine metabolic disorders (Review)

Xiu Yang, Pengcheng Li, Hao Zhao
Article Number: 279
Published online on: 05 August 2026

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Review Open Access

Contribution of p38 MAPK in liver fibrosis: An overview of mechanisms, signaling pathways, and therapeutic targets (Review)

Xueqin Yang, Huarong Li, Hao Ye, Ting Wu, Fangyun Xu, Chao Hu, Chunlei Yu, Pian Ye
Article Number: 278
Published online on: 05 August 2026

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Correction Open Access

[Corrigendum] Peroxisome proliferator‑activated receptor α regulates acesulfame‑K‑induced NAFLD via hepatic PLCβ: Foe and friend

Peng-Yao Lin, Jia-Rong Xie, Tian-Chen Qian, Shi-Song Wang, Si-Yi Yu, Wen-Bo Shi, Ying Wang, Lu-Ze Cen, Qing-Jing Zhu, Yi-Yang Zheng, Hui Gao, Rong Fang, Zhao-Xia Xia, Ai-Ming Liu, Lei Xu
Article Number: 277
Published online on: 05 August 2026

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Review Open Access

Multi‑omics insights into uveitis: From mechanisms to precision medicine (Review)

Chengzhi Liu, Qiong Wu, Mingzhen Yuan, Mingyue Liu, Xinyu Wang, Jiaqi Shen, Xusheng Cao
Article Number: 276
Published online on: 03 August 2026

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Retraction Open Access

[Retracted] Effects of miRNA‑455 on cardiac hypertrophy induced by pressure overload

Chuntao Wu, Shimin Dong, Yongjun Li
Article Number: 275
Published online on: 03 August 2026

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Article Open Access

Energy stress activates AMPK to suppress ferroptosis in neurodegenerative proteinopathies

Yuanyuan Yong, Yuxin Hu, Qian Feng, Xiaogang Zhou, Lu Yu, Dalian Qin, Jianing Mi, Jianming Wu, Jianxin Liu, Anguo Wu
Article Number: 274
Published online on: 31 July 2026

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Article Open Access

Brazilin attenuates methylglyoxal‑induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR‑mediated autophagy/apoptosis axis in vitro and in vivo

Yu Liang, Jinxiang Chen, Haiyang Li, Junjing Xiong, Jingcan You, Liqun Wang, Jianbo Wu, Youkun Zheng, Mao Luo
Article Number: 273
Published online on: 30 July 2026

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Review Open Access

Post‑translational modifications in atherosclerosis: Roles, mechanisms and therapeutic potential (Review)

Xiaoxiang Xu, Fei Ma, Wei Yu
Article Number: 272
Published online on: 30 July 2026

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Review Open Access

Role of extracellular matrix in liver fibrosis regression and regeneration (Review)

Yuanzhi Zhou, Zeyuan Qiang, Yang Duan, Jiwei Huang, Haichuan Wang
Article Number: 271
Published online on: 29 July 2026

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Correction Open Access

[Corrigendum] Circulating microRNA profiles and the identification of miR‑593 and miR‑511 which directly target the PROP1 gene in children with combined pituitary hormone deficiency

Yanyan Hu, Qian Wang, Zengmin Wang, Fengxue Wang, Xiaobo Guo, Guimei Li
Article Number: 270
Published online on: 29 July 2026

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Review Open Access

Unveiling the role of spatial transcriptomics in the analysis of the tumor immune microenvironment (Review)

Jialin Jiang, Xinyu Tu, Yi Cao, Qun Yan, Buqing Sai, Jian Ma
Article Number: 269
Published online on: 28 July 2026

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Expression of Concern Open Access

[Expression of Concern] Luteolin protects mice from severe acute pancreatitis by exerting HO‑1‑mediated anti‑inflammatory and antioxidant effects

Jie Xiong, Kezhou Wang, Chunxiao Yuan, Rong Xing, Jianbo Ni, Guoyong Hu, Fengling Chen, Xingpeng Wang
Article Number: 268
Published online on: 27 July 2026

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Article Open Access

circRNA_013145‑miR‑185‑5p‑RhoA axis: A novel mechanism in the pathophysiology of diabetes‑induced erectile dysfunction

Wenhan Huang, Xin Lv, Jiahua Qian, Yihao Chen, Yuhe Si, Jingwei Wang, Jianxiong Ma
Article Number: 267
Published online on: 24 July 2026

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Gut‑liver‑kidney axis: A systems biology framework for understanding and treating chronic kidney disease (Review)

Jinyi Hou, Yaotan Li, Shijia Lin, Qingqing Liu, Huijuan Zheng, Weijing Liu, Yaoxian Wang, Liang Peng, Zhen Wang
Article Number: 266
Published online on: 23 July 2026

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Effects of cuproptosis and its application in inflammatory bowel disease (Review)

Li Chen, Francis Atim Akanyibah, Jing Guan, Bing Pei, Bo Wang, Fei Mao
Article Number: 265
Published online on: 23 July 2026

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November-2026 Volume 58 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Targeting integrated cell death networks in sepsis‑associated acute kidney injury: Shared regulatory nodes and diet‑related small molecule modulation (Review)

Lin Song, Aifeng He, Wei Jiang, Keran Shi, Jing Wang, Lu Xu, Jiangquan Yu, Ruiqiang Zheng
Article Number: 303
Published online on: 31 August 2026

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Effect of MALT1 inhibition by MI‑2 on the microglial phenotype switch, inflammatory cytokine secretion, neuronal loss and oxidative stress in Alzheimer's disease

Yuanlong Li, Hua Fan, Xiong Han, Ming Ni, Xiaodan Hou, Hailan Xia, Yinzhu Shi, Lin Zhang, Jun Sun
Article Number: 302
Published online on: 31 August 2026

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Salvianolic acid monomers against metastasis: Decoding the multilayered interception of EMT, angiogenesis and immune evasion (Review)

Shiting Jiang, Dan Liu, Tingting Wei, Qiwei Shi, Haowen Wang, Yidan Gao, Pingsu Mao, Wenli Yang
Article Number: 301
Published online on: 31 August 2026

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Retraction Open Access

[Retracted] Silencing of decoy receptor 3 (DcR3) expression by siRNA in pancreatic carcinoma cells induces Fas ligand‑mediated apoptosis in vitro and in vivo

Jian Zhou, Shiduo Song, Songbin He, Zhenxin Wang, Bing Zhang, Dechun Li, Dongming Zhu
Article Number: 300
Published online on: 31 August 2026

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Research progress on BTG2 in non‑tumor diseases (Review)

Shuling Li, Xiaomei Liu, Zheng Zhang, Ling Yang, Yuxuan Li, Qiongdan Hu
Article Number: 299
Published online on: 28 August 2026

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Breaking the cycle of fibrosis: Ferroptosis as a therapeutic target (Review)

Xincheng Feng, Jue Zhang, Qinghong Ma, Chao Sun
Article Number: 298
Published online on: 27 August 2026

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Correction Open Access

[Corrigendum] Tumor‑targeting novel manganese complex induces ROS‑mediated apoptotic and autophagic cancer cell death

Jia Liu, Wenjie Guo, Jing Li, Xiang Li, Ji Geng, Qiuyun Chen, Jing Gao
Article Number: 297
Published online on: 26 August 2026

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Advances in sirtuin research in lung diseases (Review)

Shuangyun Xi, Weijun Chen, Xiuli Li, Yudan Wang, Yong Ke
Article Number: 296
Published online on: 25 August 2026

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lncRNA TUG1 mediates palmitic acid‑induced neuronal lipotoxic injury via the miR‑449a‑5p/caspase‑3 and Akt/GSK‑3β axes

Ya-Dong Wei, Peng-Quan Chen, Xin Zheng, Le-Qi Wu, Xin-Yi Wang, Xin-Ran Gao, Jin-Fang Ge
Article Number: 295
Published online on: 25 August 2026

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Retraction Open Access

[Retracted] Downregulation of LINC00707 promotes osteogenic differentiation of human bone marrow‑derived mesenchymal stem cells by regulating DKK1 via targeting miR‑103a‑3p

Jun Liu, Minfei Wu, Guang Feng, Rui Li, Yang Wang, Jianhang Jiao
Article Number: 294
Published online on: 24 August 2026

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