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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
August-2018 Volume 53 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

CRISPR therapeutic tools for complex genetic disorders and cancer (Review)

Stella Baliou, Maria Adamaki, Anthony M. Kyriakopoulos, Demetrios A. Spandidos, Mihalis Panayiotidis, Ioannis Christodoulou, Vassilis Zoumpourlis
Pages: 443-468
Published online on: 06 June 2018

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Review

Cancer stem cells and hypoxia-inducible factors (Review)

Wei-Wei Tong, Guang-Hui Tong, Yong Liu
Pages: 469-476
Published online on: 22 May 2018

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Review

Implications of nestin in breast cancer pathogenesis (Review)

Aleksandra Nowak, Piotr Dziegiel
Pages: 477-487
Published online on: 14 June 2018

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Article Open Access

Involvement of TIMP-1 in PECAM-1-mediated tumor dissemination

Valsamma Abraham, Gaoyuan Cao, Andrew Parambath, Fareedah Lawal, Chakkrapong Handumrongkul, Robert Debs, Horace M. DeLisser
Pages: 488-502
Published online on: 25 May 2018

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Article Open Access

Cold PSM, but not TRAIL, triggers autophagic cell death: A therapeutic advantage of PSM over TRAIL

Tomohisa Ito, Takashi Ando, Miki Suzuki-Karasaki, Tomohiko Tokunaga, Yukihiro Yoshida, Toyoko Ochiai, Yasuaki Tokuhashi, Yoshihiro Suzuki-Karasaki
Pages: 503-514
Published online on: 21 May 2018

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Article Open Access

Curcumin inhibits cell proliferation and motility via suppression of TROP2 in bladder cancer cells

Lianhua Zhang, Guoliang Yang, Ruiyun Zhang, Liang Dong, Haige Chen, Juanjie Bo, Wei Xue , Yiran Huang
Pages: 515-526
Published online on: 30 May 2018

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Article Open Access

Exosome-mediated transfer of lncRNA RP11‑838N2.4 promotes erlotinib resistance in non-small cell lung cancer Retraction in /10.3892/ijo.2022.5458

Wei Zhang, Xinrui Cai, Jie Yu, Xuxiang Lu, Qiuhai Qian, Weibin Qian
Pages: 527-538
Published online on: 17 May 2018

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Article Open Access

Microwave hyperthermia promotes caspase‑3-dependent apoptosis and induces G2/M checkpoint arrest via the ATM pathway in non‑small cell lung cancer cells

Yan-Yan Zhao, Qiong Wu, Zhi-Bing Wu, Jing-Jing Zhang, Lu-Cheng Zhu, Yang Yang, Sheng-Lin Ma, Shi-Rong Zhang
Pages: 539-550
Published online on: 13 June 2018

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Article Open Access

lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma

Xiao Li, Qi Zhao, Jianni Qi, Wenwen Wang, Di Zhang, Zhen Li, Chengyong Qin
Pages: 551-566
Published online on: 23 May 2018

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Article Open Access

E2F1/SP3/STAT6 axis is required for IL-4-induced epithelial-mesenchymal transition of colorectal cancer cells

Jiaoe Chen, Chaoju Gong, Huiqin Mao, Zhaoyun Li, Zejun Fang, Qiang Chen, Min Lin, Xiang Jiang, Yanyan Hu, Wei Wang, Xiaomin Zhang, Xianjun Chen, Hongzhang Li
Pages: 567-578
Published online on: 05 June 2018

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Article Open Access

Early synergistic interactions between the HPV16‑E7 oncoprotein and 17β-oestradiol for repressing the expression of Granzyme B in a cervical cancer model

J. Antonio Munguía-Moreno, José Díaz‑Chavéz, Enrique García-Villa, M. Estela Albino-Sanchez, Daniel Mendoza-Villanueva, Rodolfo Ocadiz-Delgado, José Bonilla-Delgado, Armando Marín‑Flores, Enoc M. Cortés-Malagón, Elizabeth Alvarez-Rios, Alfredo Hidalgo-Miranda, Aykut Üren, Haydar Çelik, Paul F. Lambert, Patricio Gariglio
Pages: 579-591
Published online on: 06 June 2018

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Article Open Access

Interaction of S100A1 with LATS1 promotes cell growth through regulation of the Hippo pathway in hepatocellular carcinoma Retraction in /10.3892/ijo.2023.5603

Qingping Guo, Jiale Wang, Zeyu Cao, Yongchang Tang, Chao Feng, Feizhou Huang
Pages: 592-602
Published online on: 05 June 2018

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Article Open Access

Comprehensive analysis of the clinical significance and prospective molecular mechanisms of differentially expressed autophagy-related genes in thyroid cancer

Peng Lin, Yun He, Dong-Yue Wen, Xiao-Jiao Li, Jing-Jing Zeng, Wei-Jia Mo, Qing Li, Jin-Bo Peng, Yu-Quan Wu, Deng-Hua Pan, Hai-Yuan Li, Qiu-Yan Mo, Yun-Peng Wei, Hong Yang, Gang Chen
Pages: 603-619
Published online on: 11 May 2018

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Article Open Access

TRIM27 functions as an oncogene by activating epithelial-mesenchymal transition and p-AKT in colorectal cancer

Yue Zhang, Yifei Feng, Dongjian Ji, Qingyuan Wang, Wenwei Qian, Shijia Wang, Zhiyuan Zhang, Bing Ji, Chuan Zhang, Yueming Sun, Zan Fu
Pages: 620-632
Published online on: 16 May 2018

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Article Open Access

A novel scoring system for gastric cancer risk assessment based on the expression of three CLIP4 DNA methylation-associated genes

Chenggong Hu, Yongfang Zhou, Chang Liu, Yan Kang
Pages: 633-643
Published online on: 06 June 2018

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Article Open Access

MicroRNA-125a-5p enhances the sensitivity of esophageal squamous cell carcinoma cells to cisplatin by suppressing the activation of the STAT3 signaling pathway

Yan Zhao, Ke Ma, Shujun Yang, Xiaosan Zhang, Feng Wang, Xiaqing Zhang, Hongtao Liu, Qingxia Fan
Pages: 644-658
Published online on: 16 May 2018

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Article Open Access

High mobility group box 1 promotes the epithelial-to-mesenchymal transition in prostate cancer PC3 cells via the RAGE/NF-κB signaling pathway

Jingliang Zhang, Shuai Shao, Donghui Han, Yuerong Xu, Dian Jiao, Jieheng Wu, Fa Yang, Yufeng Ge, Shengjia Shi, Yu Li, Weihong Wen, Weijun Qin
Pages: 659-671
Published online on: 23 May 2018

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Article Open Access

WAVE3 promotes proliferation, migration and invasion via the AKT pathway in pancreatic cancer

Shaobin Huang, Chensong Huang, Wei Chen, Yifeng Liu, Xiaoyu Yin, Jiaming Lai, Lijian Liang, Qian Wang, Anxun Wang, Chaoxu Zheng
Pages: 672-684
Published online on: 25 May 2018

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Article Open Access

NRG1 regulates redox homeostasis via NRF2 in papillary thyroid cancer

Ting‑Ting Zhang, Ning Qu, Guo‑Hua Sun, Long Zhang, Yuan‑Jin Wang, Xiang‑Ming Mu, Wen‑Jun Wei, Yu‑Long Wang, Yu Wang, Qing‑Hai Ji, Yong‑Xue Zhu, Rong‑Liang Shi
Pages: 685-693
Published online on: 31 May 2018

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Article Open Access

Retrospective analysis of estrogen receptor 1 and N‑acetyltransferase gene expression in normal breast tissue, primary breast tumors, and established breast cancer cell lines

Samantha M. Carlisle, David W. Hein
Pages: 694-702
Published online on: 11 June 2018

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Article

Anticancer and radiosensitizing effects of the cyclin-dependent kinase inhibitors, AT7519 and SNS‑032, on cervical cancer

Mi Ae Kang, Wonwoo Kim, Hye-Ram Jo, Young-Joo Shin, Moon-Hong Kim, Jae-Hoon Jeong
Pages: 703-712
Published online on: 31 May 2018

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Article

Prognostic value of MAGEA4 in primary lung cancer depends on subcellular localization and p53 status

Aki Fujiwara-Kuroda, Tatsuya Kato, Takehiro Abiko, Takahiro Tsuchikawa, Noriaki Kyogoku, Masaomi Ichinokawa, Kimitaka Tanaka, Takehiro Noji, Yasuhiro Hida, Kichizo Kaga, Yoshiro Matsui, Hiroaki Ikeda, Shinichi Kageyama, Hiroshi Shiku, Satoshi Hirano
Pages: 713-724
Published online on: 31 May 2018

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Article

HRAS as a potential therapeutic target of salirasib RAS inhibitor in bladder cancer

Satoshi Sugita, Hideki Enokida, Hirofumi Yoshino, Kazutaka Miyamoto, Masaya Yonemori, Takashi Sakaguchi, Yoichi Osako, Masayuki Nakagawa
Pages: 725-736
Published online on: 11 June 2018

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Article

Colony-stimulating factor-1 and colony-stimulating factor-1 receptor co-expression is associated with disease progression in gastric cancer

Yoshinaga Okugawa, Yuji Toiyama, Takashi Ichikawa, Mikio Kawamura, Hiromi Yasuda, Hiroyuki Fujikawa, Susumu Saigusa, Masaki Ohi, Toshimitsu Araki, Koji Tanaka, Yasuhiro Inoue, Motoyoshi Tanaka, Chikao Miki, Masato Kusunoki
Pages: 737-749
Published online on: 16 May 2018

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Article

Baicalein induces the apoptosis of HCT116 human colon cancer cells via the upregulation of DEPP/Gadd45a and activation of MAPKs

Meng-Qi Su, Yi-Ran Zhou, Xuan Rao, Hong Yang, Xin‑Hao Zhuang, Xue-Jia Ke, Guang-Yong Peng, Chang-Lin Zhou, Bai-Yong Shen, Jie Dou
Pages: 750-760
Published online on: 11 May 2018

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Article

Andrographolide induces degradation of mutant p53 via activation of Hsp70

Hirofumi Sato, Masatsugu Hiraki, Takushi Namba, Noriyuki Egawa, Koichi Baba, Tomokazu Tanaka, Hirokazu Noshiro
Pages: 761-770
Published online on: 22 May 2018

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Article

miRNA expression profiling regulates necroptotic cell death in hepatocellular carcinoma

Maria Visalli, Marcello Bartolotta, Francesca Polito, Rosaria Oteri, Adalberto Barbera, Roberto Arrigo, Rosa Maria Di Giorgio, Giuseppe Navarra, M'hammed Aguennouz
Pages: 771-780
Published online on: 17 May 2018

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Article

Let‑7d inhibits colorectal cancer cell proliferation through the CST1/p65 pathway

Jie Jiang, Hui-Ling Liu, Li Tao, Xian-Yi Lin, Yi-Dong Yang, Si-Wei Tan, Bin Wu
Pages: 781-790
Published online on: 23 May 2018

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Article

Matrine exerts inhibitory effects in melanoma through the regulation of miR-19b-3p/PTEN

Yan Ping Wei, Xiang Hua Wang, Gang Liu, Jin Feng Zhang, Yong Xian Yang, Juan Zhang, Xiao Li Song, Zhong Dong Li, Lin Dong Zhao
Pages: 791-800
Published online on: 21 May 2018

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Article

Mitotic kinase PBK/TOPK as a therapeutic target for adult T‑cell leukemia/lymphoma

Chie Ishikawa, Masachika Senba, Naoki Mori
Pages: 801-814
Published online on: 01 June 2018

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Article

Nicotine inhibits CD24 expression in Lewis lung carcinoma cells by upregulation of RAS expression

Da-Hua Liu, Min An, Bai-Li Bao, Fu Ren, Pu Xia
Pages: 815-822
Published online on: 22 May 2018

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Article

Dihydrocelastrol exerts potent antitumor activity in mantle cell lymphoma cells via dual inhibition of mTORC1 and mTORC2

Yongsheng Xie, Bo Li, Wenxuan Bu, Lu Gao, Yong Zhang, Xiucai Lan, Jun Hou, Zhijian Xu, Shuaikang Chang, Dandan Yu, Bingqian Xie, Yingcong Wang, Houcai Wang, Yiwen Zhang, Xiaosong Wu, Weiliang Zhu, Jumei Shi
Pages: 823-834
Published online on: 12 June 2018

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Article

Diosmetin suppresses human prostate cancer cell proliferation through the induction of apoptosis and cell cycle arrest

Christine Oak, Ahmad O. Khalifa, Ilaha Isali, Natarajan Bhaskaran, Ethan Walker, Sanjeev Shukla
Pages: 835-843
Published online on: 16 May 2018

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Article

The HDAC6 inhibitor ACY‑1215 enhances the anticancer activity of oxaliplatin in colorectal cancer cells

Dong Hoon Lee, Hye-Rim Won, Hyun-Wook Ryu, Jung Min Han, So Hee Kwon
Pages: 844-854
Published online on: 11 May 2018

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Article

Blocking the Nav1.5 channel using eicosapentaenoic acid reduces migration and proliferation of ovarian cancer cells Corrigendum in /10.3892/ijo.2020.5129

Junxiu Liu, Dawei Liu, Jasmine J. Liu, Chang Zhao, Shuzhong Yao, Liang Hong
Pages: 855-865
Published online on: 12 June 2018

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Article

A panel of 7 prognosis-related long non-coding RNAs to improve platinum-based chemoresistance prediction in ovarian cancer

Jing Song, Wanfeng Zhang, Sen Wang, Kun Liu, Fangzhou Song, Longke Ran
Pages: 866-876
Published online on: 11 May 2018

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Article

Salidroside inhibits migration, invasion and angiogenesis of MDA‑MB 231 TNBC cells by regulating EGFR/Jak2/STAT3 signaling via MMP2

Dong Young Kang, Nipin Sp, Doh Hoon Kim, Youn Hee Joung, Hyo Gun Lee, Young Min Park, Young Mok Yang
Pages: 877-885
Published online on: 05 June 2018

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Article

Knockdown of GA-binding protein subunit β1 inhibits cell proliferation via p21 induction in renal cell carcinoma

Szu-Chia Chen, Meng-Chi Yen, Feng-Wei Chen, Ling-Yu Wu, Shiang-Jie Yang, Po-Lin Kuo, Ya-Ling Hsu
Pages: 886-894
Published online on: 17 May 2018

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Article

Deubiquitinase USP48 promotes ATRA-induced granulocytic differentiation of acute promyelocytic leukemia cells

Lianlian Li, Yong Wang, Xiaoyu Zhang, Guanhua Song, Qiang Guo, Zhiyong Zhang, Yutao Diao, Haipeng Yin, Hongyan Liu, Guosheng Jiang
Pages: 895-903
Published online on: 13 June 2018

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Article

Wnt inhibitory factor-1-mediated autophagy inhibits Wnt/β-catenin signaling by downregulating dishevelled-2 expression in non-small cell lung cancer cells

Xinmei Luo, Sujuan Ye, Qianqian Jiang, Yi Gong, Yue Yuan, Xueting Hu, Xiaolan Su, Wen Zhu
Pages: 904-914
Published online on: 15 June 2018

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Correction Open Access

[Corrigendum] Long non‑coding RNA H19 promotes cell proliferation and invasion by acting as a ceRNA of miR‑138 and releasing EZH2 in oral squamous cell carcinoma

Yonglong Hong, Haitao He, Wen Sui, Jingge Zhang, Shenfu Zhang, Dajiang Yang
Pages: 915-915
Published online on: 01 June 2018

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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