Journal Articles
Review
CRISPR therapeutic tools for complex genetic disorders and cancer (Review)
Stella Baliou, Maria Adamaki, Anthony M. Kyriakopoulos, Demetrios A. Spandidos, Mihalis Panayiotidis, Ioannis Christodoulou, Vassilis Zoumpourlis
Pages: 443-468 Published online on: 06 June 2018
Review
Cancer stem cells and hypoxia-inducible factors (Review)
Wei-Wei Tong, Guang-Hui Tong, Yong Liu
Pages: 469-476 Published online on: 22 May 2018
Review
Implications of nestin in breast cancer pathogenesis (Review)
Aleksandra Nowak, Piotr Dziegiel
Pages: 477-487 Published online on: 14 June 2018
Article
Involvement of TIMP-1 in PECAM-1-mediated tumor dissemination
Valsamma Abraham, Gaoyuan Cao, Andrew Parambath, Fareedah Lawal, Chakkrapong Handumrongkul, Robert Debs, Horace M. DeLisser
Pages: 488-502 Published online on: 25 May 2018
Article
Cold PSM, but not TRAIL, triggers autophagic cell death: A therapeutic advantage of PSM over TRAIL
Tomohisa Ito, Takashi Ando, Miki Suzuki-Karasaki, Tomohiko Tokunaga, Yukihiro Yoshida, Toyoko Ochiai, Yasuaki Tokuhashi, Yoshihiro Suzuki-Karasaki
Pages: 503-514 Published online on: 21 May 2018
Article
Curcumin inhibits cell proliferation and motility via suppression of TROP2 in bladder cancer cells
Lianhua Zhang, Guoliang Yang, Ruiyun Zhang, Liang Dong, Haige Chen, Juanjie Bo, Wei Xue , Yiran Huang
Pages: 515-526 Published online on: 30 May 2018
Article
Exosome-mediated transfer of lncRNA RP11‑838N2.4 promotes erlotinib resistance in non-small cell lung cancer Retraction in /10.3892/ijo.2022.5458
Wei Zhang, Xinrui Cai, Jie Yu, Xuxiang Lu, Qiuhai Qian, Weibin Qian
Pages: 527-538 Published online on: 17 May 2018
Article
Microwave hyperthermia promotes caspase‑3-dependent apoptosis and induces G2/M checkpoint arrest via the ATM pathway in non‑small cell lung cancer cells
Yan-Yan Zhao, Qiong Wu, Zhi-Bing Wu, Jing-Jing Zhang, Lu-Cheng Zhu, Yang Yang, Sheng-Lin Ma, Shi-Rong Zhang
Pages: 539-550 Published online on: 13 June 2018
Article
lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma
Xiao Li, Qi Zhao, Jianni Qi, Wenwen Wang, Di Zhang, Zhen Li, Chengyong Qin
Pages: 551-566 Published online on: 23 May 2018
Article
E2F1/SP3/STAT6 axis is required for IL-4-induced epithelial-mesenchymal transition of colorectal cancer cells
Jiaoe Chen, Chaoju Gong, Huiqin Mao, Zhaoyun Li, Zejun Fang, Qiang Chen, Min Lin, Xiang Jiang, Yanyan Hu, Wei Wang, Xiaomin Zhang, Xianjun Chen, Hongzhang Li
Pages: 567-578 Published online on: 05 June 2018
Article
Early synergistic interactions between the HPV16‑E7 oncoprotein and 17β-oestradiol for repressing the expression of Granzyme B in a cervical cancer model
J. Antonio Munguía-Moreno, José Díaz‑Chavéz, Enrique García-Villa, M. Estela Albino-Sanchez, Daniel Mendoza-Villanueva, Rodolfo Ocadiz-Delgado, José Bonilla-Delgado, Armando Marín‑Flores, Enoc M. Cortés-Malagón, Elizabeth Alvarez-Rios, Alfredo Hidalgo-Miranda, Aykut Üren, Haydar Çelik, Paul F. Lambert, Patricio Gariglio
Pages: 579-591 Published online on: 06 June 2018
Article
Interaction of S100A1 with LATS1 promotes cell growth through regulation of the Hippo pathway in hepatocellular carcinoma Retraction in /10.3892/ijo.2023.5603
Qingping Guo, Jiale Wang, Zeyu Cao, Yongchang Tang, Chao Feng, Feizhou Huang
Pages: 592-602 Published online on: 05 June 2018
Article
Comprehensive analysis of the clinical significance and prospective molecular mechanisms of differentially expressed autophagy-related genes in thyroid cancer
Peng Lin, Yun He, Dong-Yue Wen, Xiao-Jiao Li, Jing-Jing Zeng, Wei-Jia Mo, Qing Li, Jin-Bo Peng, Yu-Quan Wu, Deng-Hua Pan, Hai-Yuan Li, Qiu-Yan Mo, Yun-Peng Wei, Hong Yang, Gang Chen
Pages: 603-619 Published online on: 11 May 2018
Article
TRIM27 functions as an oncogene by activating epithelial-mesenchymal transition and p-AKT in colorectal cancer
Yue Zhang, Yifei Feng, Dongjian Ji, Qingyuan Wang, Wenwei Qian, Shijia Wang, Zhiyuan Zhang, Bing Ji, Chuan Zhang, Yueming Sun, Zan Fu
Pages: 620-632 Published online on: 16 May 2018
Article
A novel scoring system for gastric cancer risk assessment based on the expression of three CLIP4 DNA methylation-associated genes
Chenggong Hu, Yongfang Zhou, Chang Liu, Yan Kang
Pages: 633-643 Published online on: 06 June 2018
Article
MicroRNA-125a-5p enhances the sensitivity of esophageal squamous cell carcinoma cells to cisplatin by suppressing the activation of the STAT3 signaling pathway
Yan Zhao, Ke Ma, Shujun Yang, Xiaosan Zhang, Feng Wang, Xiaqing Zhang, Hongtao Liu, Qingxia Fan
Pages: 644-658 Published online on: 16 May 2018
Article
High mobility group box 1 promotes the epithelial-to-mesenchymal transition in prostate cancer PC3 cells via the RAGE/NF-κB signaling pathway
Jingliang Zhang, Shuai Shao, Donghui Han, Yuerong Xu, Dian Jiao, Jieheng Wu, Fa Yang, Yufeng Ge, Shengjia Shi, Yu Li, Weihong Wen, Weijun Qin
Pages: 659-671 Published online on: 23 May 2018
Article
WAVE3 promotes proliferation, migration and invasion via the AKT pathway in pancreatic cancer
Shaobin Huang, Chensong Huang, Wei Chen, Yifeng Liu, Xiaoyu Yin, Jiaming Lai, Lijian Liang, Qian Wang, Anxun Wang, Chaoxu Zheng
Pages: 672-684 Published online on: 25 May 2018
Article
NRG1 regulates redox homeostasis via NRF2 in papillary thyroid cancer
Ting‑Ting Zhang, Ning Qu, Guo‑Hua Sun, Long Zhang, Yuan‑Jin Wang, Xiang‑Ming Mu, Wen‑Jun Wei, Yu‑Long Wang, Yu Wang, Qing‑Hai Ji, Yong‑Xue Zhu, Rong‑Liang Shi
Pages: 685-693 Published online on: 31 May 2018
Article
Retrospective analysis of estrogen receptor 1 and N‑acetyltransferase gene expression in normal breast tissue, primary breast tumors, and established breast cancer cell lines
Samantha M. Carlisle, David W. Hein
Pages: 694-702 Published online on: 11 June 2018
Article
Anticancer and radiosensitizing effects of the cyclin-dependent kinase inhibitors, AT7519 and SNS‑032, on cervical cancer
Mi Ae Kang, Wonwoo Kim, Hye-Ram Jo, Young-Joo Shin, Moon-Hong Kim, Jae-Hoon Jeong
Pages: 703-712 Published online on: 31 May 2018
Article
Prognostic value of MAGEA4 in primary lung cancer depends on subcellular localization and p53 status
Aki Fujiwara-Kuroda, Tatsuya Kato, Takehiro Abiko, Takahiro Tsuchikawa, Noriaki Kyogoku, Masaomi Ichinokawa, Kimitaka Tanaka, Takehiro Noji, Yasuhiro Hida, Kichizo Kaga, Yoshiro Matsui, Hiroaki Ikeda, Shinichi Kageyama, Hiroshi Shiku, Satoshi Hirano
Pages: 713-724 Published online on: 31 May 2018
Article
HRAS as a potential therapeutic target of salirasib RAS inhibitor in bladder cancer
Satoshi Sugita, Hideki Enokida, Hirofumi Yoshino, Kazutaka Miyamoto, Masaya Yonemori, Takashi Sakaguchi, Yoichi Osako, Masayuki Nakagawa
Pages: 725-736 Published online on: 11 June 2018
Article
Colony-stimulating factor-1 and colony-stimulating factor-1 receptor co-expression is associated with disease progression in gastric cancer
Yoshinaga Okugawa, Yuji Toiyama, Takashi Ichikawa, Mikio Kawamura, Hiromi Yasuda, Hiroyuki Fujikawa, Susumu Saigusa, Masaki Ohi, Toshimitsu Araki, Koji Tanaka, Yasuhiro Inoue, Motoyoshi Tanaka, Chikao Miki, Masato Kusunoki
Pages: 737-749 Published online on: 16 May 2018
Article
Baicalein induces the apoptosis of HCT116 human colon cancer cells via the upregulation of DEPP/Gadd45a and activation of MAPKs
Meng-Qi Su, Yi-Ran Zhou, Xuan Rao, Hong Yang, Xin‑Hao Zhuang, Xue-Jia Ke, Guang-Yong Peng, Chang-Lin Zhou, Bai-Yong Shen, Jie Dou
Pages: 750-760 Published online on: 11 May 2018
Article
Andrographolide induces degradation of mutant p53 via activation of Hsp70
Hirofumi Sato, Masatsugu Hiraki, Takushi Namba, Noriyuki Egawa, Koichi Baba, Tomokazu Tanaka, Hirokazu Noshiro
Pages: 761-770 Published online on: 22 May 2018
Article
miRNA expression profiling regulates necroptotic cell death in hepatocellular carcinoma
Maria Visalli, Marcello Bartolotta, Francesca Polito, Rosaria Oteri, Adalberto Barbera, Roberto Arrigo, Rosa Maria Di Giorgio, Giuseppe Navarra, M'hammed Aguennouz
Pages: 771-780 Published online on: 17 May 2018
Article
Let‑7d inhibits colorectal cancer cell proliferation through the CST1/p65 pathway
Jie Jiang, Hui-Ling Liu, Li Tao, Xian-Yi Lin, Yi-Dong Yang, Si-Wei Tan, Bin Wu
Pages: 781-790 Published online on: 23 May 2018
Article
Matrine exerts inhibitory effects in melanoma through the regulation of miR-19b-3p/PTEN
Yan Ping Wei, Xiang Hua Wang, Gang Liu, Jin Feng Zhang, Yong Xian Yang, Juan Zhang, Xiao Li Song, Zhong Dong Li, Lin Dong Zhao
Pages: 791-800 Published online on: 21 May 2018
Article
Mitotic kinase PBK/TOPK as a therapeutic target for adult T‑cell leukemia/lymphoma
Chie Ishikawa, Masachika Senba, Naoki Mori
Pages: 801-814 Published online on: 01 June 2018
Article
Nicotine inhibits CD24 expression in Lewis lung carcinoma cells by upregulation of RAS expression
Da-Hua Liu, Min An, Bai-Li Bao, Fu Ren, Pu Xia
Pages: 815-822 Published online on: 22 May 2018
Article
Dihydrocelastrol exerts potent antitumor activity in mantle cell lymphoma cells via dual inhibition of mTORC1 and mTORC2
Yongsheng Xie, Bo Li, Wenxuan Bu, Lu Gao, Yong Zhang, Xiucai Lan, Jun Hou, Zhijian Xu, Shuaikang Chang, Dandan Yu, Bingqian Xie, Yingcong Wang, Houcai Wang, Yiwen Zhang, Xiaosong Wu, Weiliang Zhu, Jumei Shi
Pages: 823-834 Published online on: 12 June 2018
Article
Diosmetin suppresses human prostate cancer cell proliferation through the induction of apoptosis and cell cycle arrest
Christine Oak, Ahmad O. Khalifa, Ilaha Isali, Natarajan Bhaskaran, Ethan Walker, Sanjeev Shukla
Pages: 835-843 Published online on: 16 May 2018
Article
The HDAC6 inhibitor ACY‑1215 enhances the anticancer activity of oxaliplatin in colorectal cancer cells
Dong Hoon Lee, Hye-Rim Won, Hyun-Wook Ryu, Jung Min Han, So Hee Kwon
Pages: 844-854 Published online on: 11 May 2018
Article
Blocking the Nav1.5 channel using eicosapentaenoic acid reduces migration and proliferation of ovarian cancer cells Corrigendum in /10.3892/ijo.2020.5129
Junxiu Liu, Dawei Liu, Jasmine J. Liu, Chang Zhao, Shuzhong Yao, Liang Hong
Pages: 855-865 Published online on: 12 June 2018
Article
A panel of 7 prognosis-related long non-coding RNAs to improve platinum-based chemoresistance prediction in ovarian cancer
Jing Song, Wanfeng Zhang, Sen Wang, Kun Liu, Fangzhou Song, Longke Ran
Pages: 866-876 Published online on: 11 May 2018
Article
Salidroside inhibits migration, invasion and angiogenesis of MDA‑MB 231 TNBC cells by regulating EGFR/Jak2/STAT3 signaling via MMP2
Dong Young Kang, Nipin Sp, Doh Hoon Kim, Youn Hee Joung, Hyo Gun Lee, Young Min Park, Young Mok Yang
Pages: 877-885 Published online on: 05 June 2018
Article
Knockdown of GA-binding protein subunit β1 inhibits cell proliferation via p21 induction in renal cell carcinoma
Szu-Chia Chen, Meng-Chi Yen, Feng-Wei Chen, Ling-Yu Wu, Shiang-Jie Yang, Po-Lin Kuo, Ya-Ling Hsu
Pages: 886-894 Published online on: 17 May 2018
Article
Deubiquitinase USP48 promotes ATRA-induced granulocytic differentiation of acute promyelocytic leukemia cells
Lianlian Li, Yong Wang, Xiaoyu Zhang, Guanhua Song, Qiang Guo, Zhiyong Zhang, Yutao Diao, Haipeng Yin, Hongyan Liu, Guosheng Jiang
Pages: 895-903 Published online on: 13 June 2018
Article
Wnt inhibitory factor-1-mediated autophagy inhibits Wnt/β-catenin signaling by downregulating dishevelled-2 expression in non-small cell lung cancer cells
Xinmei Luo, Sujuan Ye, Qianqian Jiang, Yi Gong, Yue Yuan, Xueting Hu, Xiaolan Su, Wen Zhu
Pages: 904-914 Published online on: 15 June 2018
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