Journal Articles
Review
Endoplasmic reticulum stress, cell death and tumor: Association between endoplasmic reticulum stress and the apoptosis pathway in tumors (Review)
Xiaojing Fu, Juanjuan Cui, Xiangjun Meng, Piyu Jiang, Qiuling Zheng, Wenwen Zhao, Xuehong Chen
Pages: 801-808 Published online on: 12 January 2021
Review
Role of chemokines in hepatocellular carcinoma (Review)
Dongdong Xue, Ya Zheng, Junye Wen, Jingzhao Han, Hongfang Tuo, Yifan Liu, Yanhui Peng
Pages: 809-823 Published online on: 22 December 2020
Review
Effects and mechanisms of Eps8 on the biological behaviour of malignant tumours (Review)
Kaili Luo, Lei Zhang, Yuan Liao, Hongyu Zhou, Hongying Yang, Min Luo, Chen Qing
Pages: 824-834 Published online on: 07 January 2021
Review
CD155/TIGIT, a novel immune checkpoint in human cancers (Review)
Lu Liu, Xuewu You, Sai Han, Yu Sun, Junhua Zhang, Youzhong Zhang
Pages: 835-845 Published online on: 19 January 2021
Review
Metabolic heterogeneity and immunocompetence of infiltrating immune cells in the breast cancer microenvironment (Review)
Hongdan Chen, Yizeng Sun, Zeyu Yang, Supeng Yin, Yao Li, Mi Tang, Junping Zhu, Fan Zhang
Pages: 846-856 Published online on: 22 January 2021
Article
Identification of a PLCE1‑regulated competing endogenous RNA regulatory network for esophageal squamous cell carcinoma
Zhihao Yang, Yi Hui, Hao Peng, Hongpan Zhang, Menglu Li, Lingxie Song, Feng Li, Xiaobin Cui
Pages: 857-868 Published online on: 04 January 2021
Article
Combination treatment with VPA and MSCs‑TRAIL could increase anti‑tumor effects against intracranial glioma
Soon A. Park, Hye Rim Han, Stephen Ahn, Chung Heon Ryu, Sin‑Soo Jeun
Pages: 869-878 Published online on: 14 January 2021
Article
Waterpipe smoke condensate influences epithelial to mesenchymal transition and interferes with the cytotoxic immune response in non-small cell lung cancer cell lines
Rania Faouzi Zaarour, Prathibha Prasad, Goutham Hassan Venkatesh, Raefa Abou Khouzam, Francis Amirtharaj, Nagwa Zeinelabdin, Ayesha Rifath, Stephane Terry, Husam Nawafleh, Yehya El Sayed, Salem Chouaib
Pages: 879-890 Published online on: 18 January 2021
Review
Potentially life‑threatening severe cutaneous adverse reactions associated with tyrosine kinase inhibitors (Review)
Emily L. Coleman, Brianna Olamiju, Jonathan S. Leventhal
Pages: 891-898 Published online on: 24 December 2020
Article
HIPK2 is a potential predictive marker of a favorable response for adjuvant chemotherapy in stage II colorectal cancer
Alessandra Verdina, Micol Di Segni, Carla Azzurra Amoreo, Isabella Sperduti, Simonetta Buglioni, Marcella Mottolese, Giuliana Di Rocco, Silvia Soddu
Pages: 899-910 Published online on: 24 December 2020
Article
MicroRNA‑34a‑5p serves as a tumor suppressor by regulating the cell motility of bladder cancer cells through matrix metalloproteinase‑2 silencing
Kuang‑Yu Chou, An‑Chen Chang, Te‑Fu Tsai, Yi‑Chia Lin, Hung‑En Chen, Chao‑Yen Ho, Po‑Chun Chen, Thomas I‑Sheng Hwang
Pages: 911-920 Published online on: 24 December 2020
Article
CDCA5 promotes the progression of prostate cancer by affecting the ERK signalling pathway Corrigendum in /10.3892/or.2023.8602
Junpeng Ji, Tianyu Shen, Yang Li, Yixi Liu, Zhiqun Shang, Yuanjie Niu
Pages: 921-932 Published online on: 04 January 2021
Article
MicroRNA‑642a‑5p inhibits colon cancer cell migration and invasion by targeting collagen type I α1
Xiaoguang Wang, Zhengwei Song, Biwen Hu, Zhenwei Chen, Fei Chen, Chenxi Cao
Pages: 933-944 Published online on: 18 December 2020
Article
Immunomodulatory potential of anticancer therapy composed of methotrexate nanoconjugate and dendritic cell‑based vaccines in murine colon carcinoma
Agnieszka Szczygieł, Natalia Anger‑Góra, Katarzyna Węgierek‑Ciura, Jagoda Mierzejewska, Joanna Rossowska, Tomasz M. Goszczyński, Marta Świtalska, Elżbieta Pajtasz‑Piasecka
Pages: 945-962 Published online on: 11 January 2021
Article
Use of miR‑145 and testicular nuclear receptor 4 inhibition to reduce chemoresistance to docetaxel in prostate cancer
Jin Zhu, Peibo Qin, Cheng Cao, Guangcheng Dai, Lijun Xu, Dongrong Yang
Pages: 963-974 Published online on: 05 January 2021
Article
VSP‑17 suppresses the migration and invasion of triple‑negative breast cancer cells through inhibition of the EMT process via the PPARγ/AMPK signaling pathway
Xiaotian Xu, Meng Liu, Yingying Yang, Chengqiong Wei, Xiyang Zhang, Hengzhi Song, Yuhui Wang, Xiaoqun Duan
Pages: 975-986 Published online on: 30 December 2020
Article
Beclin1‑armed oncolytic Vaccinia virus enhances the therapeutic efficacy of R‑CHOP against lymphoma in vitro and in vivo
Shufang Xie, Weimin Fan, Chen Yang, Wen Lei, Hongying Pan, Xiangmin Tong, Yi Wu, Shibing Wang
Pages: 987-996 Published online on: 19 January 2021
Article
GLI2 but not GLI1/GLI3 plays a central role in the induction of malignant phenotype of gallbladder cancer
Shu Ichimiya, Hideya Onishi, Shinjiro Nagao, Satoko Koga, Kukiko Sakihama, Kazunori Nakayama, Akiko Fujimura, Yasuhiro Oyama, Akira Imaizumi, Yoshinao Oda, Masafumi Nakamura
Pages: 997-1010 Published online on: 22 January 2021
Article
Dll4/Notch1 signalling pathway is required in collective invasion of salivary adenoid cystic carcinoma Corrigendum in /10.3892/or.2022.8268
Ke Wang, Hua‑Yang Fan, Xing Pang, Mei Zhang, Xiang‑Hua Yu, Jia‑Shun Wu, Bing‑Jun Chen, Jian Jiang, Xin‑Hua Liang, Ya‑Ling Tang
Pages: 1011-1022 Published online on: 18 January 2021
Article
Tissue factor pathway inhibitor‑2 is specifically expressed in ovarian clear cell carcinoma tissues in the nucleus, cytoplasm and extracellular matrix
Yukihide Ota, Shiro Koizume, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Tomoko Takahashi, Shinya Sato, Shohei Myoba, Norihisa Ohtake, Hisamori Kato, Tomoyuki Yokose, Etsuko Miyagi, Yohei Miyagi
Pages: 1023-1032 Published online on: 20 January 2021
Article
Circadian clock protein CRY1 prevents paclitaxel‑induced senescence of bladder cancer cells by promoting p53 degradation
Min Jia, Bijia Su, Lijun Mo, Wen Qiu, Jiaxu Ying, Peng Lin, Bingxuan Yang, Danying Li, Dongxia Wang, Lili Xu, Hongwei Li, Zhongxin Zhou, Xing Li, Jinlong Li
Pages: 1033-1043 Published online on: 30 December 2020
Article
Nucleolar and spindle‑associated protein 1 promotes non‑small cell lung cancer progression and serves as an effector of myocyte enhancer factor 2D
Bo Ling, Pengya Wei, Juan Xiao, Bingkui Cen, Hong Wei, Xueping Feng, Guangbin Ye, Songbo Li, Zhongwei Zhang, Wei Liang, Suoyi Huang, Wei Huang
Pages: 1044-1058 Published online on: 30 December 2020
Article
Long non‑coding RNA CASC15 facilitates esophageal squamous cell carcinoma tumorigenesis via decreasing SIM2 stability via FTO‑mediated demethylation
Bo Qin, Meng Dong, Zhengyang Wang, Jiajia Wan, Yingying Xie, Yi Jiao, Dan Yan
Pages: 1059-1071 Published online on: 30 December 2020
Article
Hsa_circ_0008537 facilitates liver carcinogenesis by upregulating MCL1 and Snail1 expression via miR‑153‑3p
Ge Yang, Xianyong Li, Jingbo Liu, Shengjie Huang, Yaguang Weng, Jing Zhu, Daiqiong Lin, Ou Jiang
Pages: 1072-1082 Published online on: 19 January 2021
Article
lncRNA HOTAIRM1 regulates cell proliferation and the metastasis of thyroid cancer by targeting Wnt10b
Chenyao Li, Xinxin Chen, Tao Liu, Guang Chen
Pages: 1083-1093 Published online on: 31 December 2020
Article
Long non‑coding RNA AFAP1‑AS1 facilitates the growth and invasiveness of oral squamous cell carcinoma by regulating the miR‑145/HOXA1 axis Retraction in /10.3892/or.2022.8306
Minghe Li, Dongsheng Yu, Zhihong Li, Cong Zhao, Chang Su, Jun Ning
Pages: 1094-1104 Published online on: 24 December 2020
Article
IL‑6 plays a crucial role in epithelial‑mesenchymal transition and pro‑metastasis induced by sorafenib in liver cancer
Ke‑Wei Zhang, Dong Wang, Hao Cai, Man‑Qing Cao, Yuan‑Yuan Zhang, Peng‑Yuan Zhuang, Jun Shen
Pages: 1105-1117 Published online on: 07 January 2021
Article
lncRNA PART1, manipulated by transcriptional factor FOXP2, suppresses proliferation and invasion in ESCC by regulating the miR‑18a‑5p/SOX6 signaling axis
Yan Zhao, Qing Zhang, Hongtao Liu, Ning Wang, Xiaosan Zhang, Shujun Yang
Pages: 1118-1132 Published online on: 11 January 2021
Article
Catechol enhances chemo‑ and radio‑sensitivity by targeting AMPK/Hippo signaling in pancreatic cancer cells
Jeong Yong Moon, Meran Keshawa Ediriweera, Ji Yeon Ryu, Hee Young Kim, Somi Kim Cho
Pages: 1133-1141 Published online on: 05 January 2021
Article
In vitro and ex vivo anti‑tumor effect and mechanism of Tucatinib in leukemia stem cells and ABCG2‑overexpressing leukemia cells
Wen Jing, Mao Zhou, Ruixia Chen, Xijiu Ye, Weixing Li, Xiangfei Su, Jianwei Luo, Zhi Wang, Shuling Peng
Pages: 1142-1152 Published online on: 30 December 2020
Article
Radiation exposure triggers the malignancy of non‑small cell lung cancer cells through the activation of visfatin/Snail signaling
Liang Xiao, Yiwen Mao, Zhuting Tong, Ye Zhao, Hao Hong, Fan Wang
Pages: 1153-1161 Published online on: 08 January 2021
Article
JMJD2C triggers the growth of multiple myeloma cells via activation of β‑catenin
Ming Lv, Qicai Liu
Pages: 1162-1170 Published online on: 14 January 2021
Article
Critical immunosuppressive effect of MDSC‑derived exosomes in the tumor microenvironment
Mohammad H. Rashid, Thaiz F. Borin, Roxan Ara, Raziye Piranlioglu, Bhagelu R. Achyut, Hasan Korkaya, Yutao Liu, Ali S. Arbab
Pages: 1171-1181 Published online on: 14 January 2021
Article
High expression of Rab31 confers a poor prognosis and enhances cell proliferation and invasion in oral squamous cell carcinoma
Xiaoguang Li, Fengshuo Zhu, Zhonglong Liu, Xiao Tang, Yu Han, Junjian Jiang, Chunyue Ma, Yue He
Pages: 1182-1192 Published online on: 18 January 2021
Article
Acanthopanax senticosus Harms extract causes G0/G1 cell cycle arrest and autophagy via inhibition of Rubicon in human liver cancer cells
Yutaka Kawano, Maki Tanaka, Masaki Fujishima, Eri Okumura, Hideo Takekoshi, Kohichi Takada, Osamu Uehara, Yoshihiro Abiko, Hidekatsu Takeda
Pages: 1193-1201 Published online on: 22 January 2021
Article
LINC00665 functions as a competitive endogenous RNA to regulate AGTR1 expression by sponging miR‑34a‑5p in glioma
Yongyue Dai, Yucheng Zhang, Maolin Hao, Renwu Zhu
Pages: 1202-1212 Published online on: 22 January 2021
Article
DDX41 regulates the expression and alternative splicing of genes involved in tumorigenesis and immune response
Kai Qin, Danni Jian, Yaqiang Xue, Yi Cheng, Peng Zhang, Yaxun Wei, Jing Zhang, Huihua Xiong, Yi Zhang, Xianglin Yuan
Pages: 1213-1225 Published online on: 25 January 2021
Article
ESM1/HIF‑1α pathway modulates chronic intermittent hypoxia‑induced non‑small‑cell lung cancer proliferation, stemness and epithelial‑mesenchymal transition
Xin Gu, Jie Zhang, Yuheng Shi, Haiji Shen, Yao Li, Yanyan Chen, Li Liang
Pages: 1226-1234 Published online on: 30 December 2020
Article
Low microRNA150 expression is associated with activated carcinogenic pathways and a poor prognosis in patients with breast cancer
San‑Qi An, Ke He, Fei Liu, Qian‑Shan Ding, Yan‑Li Wei, Zheng‑Lin Xia, Xiao‑Peng Duan, Rui Huang, Bo‑Wei Li, Hai‑He Wang, Yu Tian, Guo‑An Xiang, Wen‑Xing Li
Pages: 1235-1248 Published online on: 21 January 2021
Article
Metformin inhibits mTOR and c-Myc by decreasing YAP protein expression in OSCC cells
Ying Wang, Yafei Zhang, Xiaomei Feng, Hui Tian, Xucheng Fu, Weiting Gu, Yong Wen
Pages: 1249-1260 Published online on: 24 December 2020
Article
DMAPT‑D6 induces death‑receptor‑mediated apoptosis to inhibit glioblastoma cell oncogenesis via induction of DNA damage through accumulation of intracellular ROS
Ya‑Jun Zhang, Dong‑Lin Yang, Hong‑Xia Qin, Liu‑Jun He, Jiu‑Hong Huang, Dian‑Yong Tang, Zhi‑Gang Xu, Zhong‑Zhu Chen, Yong Li
Pages: 1261-1272 Published online on: 12 January 2021
Article
Expression of immune response biomarkers (PD‑L1, p16, CD3+ and CD8+ TILs) in recurrent head and neck squamous cell carcinoma within previously irradiated areas
Carole Pflumio, Jacques Thomas, Julia Salleron, Jean‑Christophe Faivre, Christian Borel, Gilles Dolivet, Xavier Sastre‑Garau, Lionnel Geoffrois
Pages: 1273-1283 Published online on: 07 January 2021
Article
Acidic microenvironment induction of interleukin-8 expression and matrix metalloproteinase-2/-9 activation via acid-sensing ion channel 1 promotes breast cancer cell progression
Masako Nakanishi, Ayaka Korechika, Haruka Yamakawa, Naoko Kawabe, Kazuma Nakai, Yasuteru Muragaki
Pages: 1284-1294 Published online on: 24 December 2020
Article
Role of ERCC5 polymorphisms in non‑small cell lung cancer risk and responsiveness/toxicity to cisplatin‑based chemotherapy in the Chinese population
Miao Li, Rong Chen, Baoyan Ji, Chunmei Fan, Guanying Wang, Chenli Yue, Guoquan Jin
Pages: 1295-1305 Published online on: 14 January 2021
Article
Repurposing of a monoamine oxidase A inhibitor‑heptamethine carbocyanine dye conjugate for paclitaxel‑resistant non‑small cell lung cancer
Xiao‑Guang Yang, Yan‑Yu Li, Dong‑Xue Zhao, Wei Cui, Han Li, Xin‑Yu Li, Yu‑Xin Li, Dun Wang
Pages: 1306-1314 Published online on: 22 January 2021
Correction
[Corrigendum] Exogenous hydrogen sulfide exerts proliferation, anti-apoptosis, migration effects and accelerates cell cycle progression in multiple myeloma cells via activating the Akt pathway
Dong Zheng, Ziang Chen, Jingfu Chen, Xiaomin Zhuang, Jianqiang Feng, Juan Li
Pages: 1315-1315 Published online on: 05 January 2021
Correction
