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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March-2021 Volume 45 Issue 3

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Endoplasmic reticulum stress, cell death and tumor: Association between endoplasmic reticulum stress and the apoptosis pathway in tumors (Review)

Xiaojing Fu, Juanjuan Cui, Xiangjun Meng, Piyu Jiang, Qiuling Zheng, Wenwen Zhao, Xuehong Chen
Pages: 801-808
Published online on: 12 January 2021

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Review Open Access

Role of chemokines in hepatocellular carcinoma (Review)

Dongdong Xue, Ya Zheng, Junye Wen, Jingzhao Han, Hongfang Tuo, Yifan Liu, Yanhui Peng
Pages: 809-823
Published online on: 22 December 2020

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Review Open Access

Effects and mechanisms of Eps8 on the biological behaviour of malignant tumours (Review)

Kaili Luo, Lei Zhang, Yuan Liao, Hongyu Zhou, Hongying Yang, Min Luo, Chen Qing
Pages: 824-834
Published online on: 07 January 2021

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Review

CD155/TIGIT, a novel immune checkpoint in human cancers (Review)

Lu Liu, Xuewu You, Sai Han, Yu Sun, Junhua Zhang, Youzhong Zhang
Pages: 835-845
Published online on: 19 January 2021

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Review Open Access

Metabolic heterogeneity and immunocompetence of infiltrating immune cells in the breast cancer microenvironment (Review)

Hongdan Chen, Yizeng Sun, Zeyu Yang, Supeng Yin, Yao Li, Mi Tang, Junping Zhu, Fan Zhang
Pages: 846-856
Published online on: 22 January 2021

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Article Open Access

Identification of a PLCE1‑regulated competing endogenous RNA regulatory network for esophageal squamous cell carcinoma

Zhihao Yang, Yi Hui, Hao Peng, Hongpan Zhang, Menglu Li, Lingxie Song, Feng Li, Xiaobin Cui
Pages: 857-868
Published online on: 04 January 2021

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Article Open Access

Combination treatment with VPA and MSCs‑TRAIL could increase anti‑tumor effects against intracranial glioma

Soon A. Park, Hye Rim Han, Stephen Ahn, Chung Heon Ryu, Sin‑Soo Jeun
Pages: 869-878
Published online on: 14 January 2021

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Article Open Access

Waterpipe smoke condensate influences epithelial to mesenchymal transition and interferes with the cytotoxic immune response in non-small cell lung cancer cell lines

Rania Faouzi Zaarour, Prathibha Prasad, Goutham Hassan Venkatesh, Raefa Abou Khouzam, Francis Amirtharaj, Nagwa Zeinelabdin, Ayesha Rifath, Stephane Terry, Husam Nawafleh, Yehya El Sayed, Salem Chouaib
Pages: 879-890
Published online on: 18 January 2021

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Review

Potentially life‑threatening severe cutaneous adverse reactions associated with tyrosine kinase inhibitors (Review)

Emily L. Coleman, Brianna Olamiju, Jonathan S. Leventhal
Pages: 891-898
Published online on: 24 December 2020

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Article

HIPK2 is a potential predictive marker of a favorable response for adjuvant chemotherapy in stage II colorectal cancer

Alessandra Verdina, Micol Di Segni, Carla Azzurra Amoreo, Isabella Sperduti, Simonetta Buglioni, Marcella Mottolese, Giuliana Di Rocco, Silvia Soddu
Pages: 899-910
Published online on: 24 December 2020

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Article Open Access

MicroRNA‑34a‑5p serves as a tumor suppressor by regulating the cell motility of bladder cancer cells through matrix metalloproteinase‑2 silencing

Kuang‑Yu Chou, An‑Chen Chang, Te‑Fu Tsai, Yi‑Chia Lin, Hung‑En Chen, Chao‑Yen Ho, Po‑Chun Chen, Thomas I‑Sheng Hwang
Pages: 911-920
Published online on: 24 December 2020

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Article Open Access

CDCA5 promotes the progression of prostate cancer by affecting the ERK signalling pathway Corrigendum in /10.3892/or.2023.8602

Junpeng Ji, Tianyu Shen, Yang Li, Yixi Liu, Zhiqun Shang, Yuanjie Niu
Pages: 921-932
Published online on: 04 January 2021

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Article Open Access

MicroRNA‑642a‑5p inhibits colon cancer cell migration and invasion by targeting collagen type I α1 Retraction in /10.3892/or.2024.8795

Xiaoguang Wang, Zhengwei Song, Biwen Hu, Zhenwei Chen, Fei Chen, Chenxi Cao
Pages: 933-944
Published online on: 18 December 2020

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Article Open Access

Immunomodulatory potential of anticancer therapy composed of methotrexate nanoconjugate and dendritic cell‑based vaccines in murine colon carcinoma

Agnieszka Szczygieł, Natalia Anger‑Góra, Katarzyna Węgierek‑Ciura, Jagoda Mierzejewska, Joanna Rossowska, Tomasz M. Goszczyński, Marta Świtalska, Elżbieta Pajtasz‑Piasecka
Pages: 945-962
Published online on: 11 January 2021

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Article Open Access

Use of miR‑145 and testicular nuclear receptor 4 inhibition to reduce chemoresistance to docetaxel in prostate cancer

Jin Zhu, Peibo Qin, Cheng Cao, Guangcheng Dai, Lijun Xu, Dongrong Yang
Pages: 963-974
Published online on: 05 January 2021

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Article Open Access

VSP‑17 suppresses the migration and invasion of triple‑negative breast cancer cells through inhibition of the EMT process via the PPARγ/AMPK signaling pathway

Xiaotian Xu, Meng Liu, Yingying Yang, Chengqiong Wei, Xiyang Zhang, Hengzhi Song, Yuhui Wang, Xiaoqun Duan
Pages: 975-986
Published online on: 30 December 2020

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Article Open Access

Beclin1‑armed oncolytic Vaccinia virus enhances the therapeutic efficacy of R‑CHOP against lymphoma in vitro and in vivo

Shufang Xie, Weimin Fan, Chen Yang, Wen Lei, Hongying Pan, Xiangmin Tong, Yi Wu, Shibing Wang
Pages: 987-996
Published online on: 19 January 2021

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Article Open Access

GLI2 but not GLI1/GLI3 plays a central role in the induction of malignant phenotype of gallbladder cancer

Shu Ichimiya, Hideya Onishi, Shinjiro Nagao, Satoko Koga, Kukiko Sakihama, Kazunori Nakayama, Akiko Fujimura, Yasuhiro Oyama, Akira Imaizumi, Yoshinao Oda, Masafumi Nakamura
Pages: 997-1010
Published online on: 22 January 2021

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Article Open Access

Dll4/Notch1 signalling pathway is required in collective invasion of salivary adenoid cystic carcinoma Corrigendum in /10.3892/or.2022.8268

Ke Wang, Hua‑Yang Fan, Xing Pang, Mei Zhang, Xiang‑Hua Yu, Jia‑Shun Wu, Bing‑Jun Chen, Jian Jiang, Xin‑Hua Liang, Ya‑Ling Tang
Pages: 1011-1022
Published online on: 18 January 2021

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Article Open Access

Tissue factor pathway inhibitor‑2 is specifically expressed in ovarian clear cell carcinoma tissues in the nucleus, cytoplasm and extracellular matrix

Yukihide Ota, Shiro Koizume, Yoshiyasu Nakamura, Mitsuyo Yoshihara, Tomoko Takahashi, Shinya Sato, Shohei Myoba, Norihisa Ohtake, Hisamori Kato, Tomoyuki Yokose, Etsuko Miyagi, Yohei Miyagi
Pages: 1023-1032
Published online on: 20 January 2021

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Article Open Access

Circadian clock protein CRY1 prevents paclitaxel‑induced senescence of bladder cancer cells by promoting p53 degradation

Min Jia, Bijia Su, Lijun Mo, Wen Qiu, Jiaxu Ying, Peng Lin, Bingxuan Yang, Danying Li, Dongxia Wang, Lili Xu, Hongwei Li, Zhongxin Zhou, Xing Li, Jinlong Li
Pages: 1033-1043
Published online on: 30 December 2020

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Article Open Access

Nucleolar and spindle‑associated protein 1 promotes non‑small cell lung cancer progression and serves as an effector of myocyte enhancer factor 2D

Bo Ling, Pengya Wei, Juan Xiao, Bingkui Cen, Hong Wei, Xueping Feng, Guangbin Ye, Songbo Li, Zhongwei Zhang, Wei Liang, Suoyi Huang, Wei Huang
Pages: 1044-1058
Published online on: 30 December 2020

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Article Open Access

Long non‑coding RNA CASC15 facilitates esophageal squamous cell carcinoma tumorigenesis via decreasing SIM2 stability via FTO‑mediated demethylation

Bo Qin, Meng Dong, Zhengyang Wang, Jiajia Wan, Yingying Xie, Yi Jiao, Dan Yan
Pages: 1059-1071
Published online on: 30 December 2020

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Article Open Access

Hsa_circ_0008537 facilitates liver carcinogenesis by upregulating MCL1 and Snail1 expression via miR‑153‑3p

Ge Yang, Xianyong Li, Jingbo Liu, Shengjie Huang, Yaguang Weng, Jing Zhu, Daiqiong Lin, Ou Jiang
Pages: 1072-1082
Published online on: 19 January 2021

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Article Open Access

lncRNA HOTAIRM1 regulates cell proliferation and the metastasis of thyroid cancer by targeting Wnt10b

Chenyao Li, Xinxin Chen, Tao Liu, Guang Chen
Pages: 1083-1093
Published online on: 31 December 2020

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Article Open Access

Long non‑coding RNA AFAP1‑AS1 facilitates the growth and invasiveness of oral squamous cell carcinoma by regulating the miR‑145/HOXA1 axis Retraction in /10.3892/or.2022.8306

Minghe Li, Dongsheng Yu, Zhihong Li, Cong Zhao, Chang Su, Jun Ning
Pages: 1094-1104
Published online on: 24 December 2020

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Article Open Access

IL‑6 plays a crucial role in epithelial‑mesenchymal transition and pro‑metastasis induced by sorafenib in liver cancer

Ke‑Wei Zhang, Dong Wang, Hao Cai, Man‑Qing Cao, Yuan‑Yuan Zhang, Peng‑Yuan Zhuang, Jun Shen
Pages: 1105-1117
Published online on: 07 January 2021

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Article Open Access

lncRNA PART1, manipulated by transcriptional factor FOXP2, suppresses proliferation and invasion in ESCC by regulating the miR‑18a‑5p/SOX6 signaling axis

Yan Zhao, Qing Zhang, Hongtao Liu, Ning Wang, Xiaosan Zhang, Shujun Yang
Pages: 1118-1132
Published online on: 11 January 2021

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Article Open Access

Catechol enhances chemo‑ and radio‑sensitivity by targeting AMPK/Hippo signaling in pancreatic cancer cells

Jeong Yong Moon, Meran Keshawa Ediriweera, Ji Yeon Ryu, Hee Young Kim, Somi Kim Cho
Pages: 1133-1141
Published online on: 05 January 2021

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Article Open Access

In vitro and ex vivo anti‑tumor effect and mechanism of Tucatinib in leukemia stem cells and ABCG2‑overexpressing leukemia cells

Wen Jing, Mao Zhou, Ruixia Chen, Xijiu Ye, Weixing Li, Xiangfei Su, Jianwei Luo, Zhi Wang, Shuling Peng
Pages: 1142-1152
Published online on: 30 December 2020

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Article Open Access

Radiation exposure triggers the malignancy of non‑small cell lung cancer cells through the activation of visfatin/Snail signaling

Liang Xiao, Yiwen Mao, Zhuting Tong, Ye Zhao, Hao Hong, Fan Wang
Pages: 1153-1161
Published online on: 08 January 2021

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Article Open Access

JMJD2C triggers the growth of multiple myeloma cells via activation of β‑catenin

Ming Lv, Qicai Liu
Pages: 1162-1170
Published online on: 14 January 2021

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Article Open Access

Critical immunosuppressive effect of MDSC‑derived exosomes in the tumor microenvironment

Mohammad H. Rashid, Thaiz F. Borin, Roxan Ara, Raziye Piranlioglu, Bhagelu R. Achyut, Hasan Korkaya, Yutao Liu, Ali S. Arbab
Pages: 1171-1181
Published online on: 14 January 2021

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Article Open Access

High expression of Rab31 confers a poor prognosis and enhances cell proliferation and invasion in oral squamous cell carcinoma

Xiaoguang Li, Fengshuo Zhu, Zhonglong Liu, Xiao Tang, Yu Han, Junjian Jiang, Chunyue Ma, Yue He
Pages: 1182-1192
Published online on: 18 January 2021

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Article Open Access

Acanthopanax senticosus Harms extract causes G0/G1 cell cycle arrest and autophagy via inhibition of Rubicon in human liver cancer cells

Yutaka Kawano, Maki Tanaka, Masaki Fujishima, Eri Okumura, Hideo Takekoshi, Kohichi Takada, Osamu Uehara, Yoshihiro Abiko, Hidekatsu Takeda
Pages: 1193-1201
Published online on: 22 January 2021

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Article Open Access

LINC00665 functions as a competitive endogenous RNA to regulate AGTR1 expression by sponging miR‑34a‑5p in glioma Retraction in /10.3892/or.2024.8773

Yongyue Dai, Yucheng Zhang, Maolin Hao, Renwu Zhu
Pages: 1202-1212
Published online on: 22 January 2021

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Article Open Access

DDX41 regulates the expression and alternative splicing of genes involved in tumorigenesis and immune response

Kai Qin, Danni Jian, Yaqiang Xue, Yi Cheng, Peng Zhang, Yaxun Wei, Jing Zhang, Huihua Xiong, Yi Zhang, Xianglin Yuan
Pages: 1213-1225
Published online on: 25 January 2021

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Article

ESM1/HIF‑1α pathway modulates chronic intermittent hypoxia‑induced non‑small‑cell lung cancer proliferation, stemness and epithelial‑mesenchymal transition

Xin Gu, Jie Zhang, Yuheng Shi, Haiji Shen, Yao Li, Yanyan Chen, Li Liang
Pages: 1226-1234
Published online on: 30 December 2020

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Article

Low microRNA150 expression is associated with activated carcinogenic pathways and a poor prognosis in patients with breast cancer

San‑Qi An, Ke He, Fei Liu, Qian‑Shan Ding, Yan‑Li Wei, Zheng‑Lin Xia, Xiao‑Peng Duan, Rui Huang, Bo‑Wei Li, Hai‑He Wang, Yu Tian, Guo‑An Xiang, Wen‑Xing Li
Pages: 1235-1248
Published online on: 21 January 2021

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Article

Metformin inhibits mTOR and c-Myc by decreasing YAP protein expression in OSCC cells

Ying Wang, Yafei Zhang, Xiaomei Feng, Hui Tian, Xucheng Fu, Weiting Gu, Yong Wen
Pages: 1249-1260
Published online on: 24 December 2020

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Article

DMAPT‑D6 induces death‑receptor‑mediated apoptosis to inhibit glioblastoma cell oncogenesis via induction of DNA damage through accumulation of intracellular ROS

Ya‑Jun Zhang, Dong‑Lin Yang, Hong‑Xia Qin, Liu‑Jun He, Jiu‑Hong Huang, Dian‑Yong Tang, Zhi‑Gang Xu, Zhong‑Zhu Chen, Yong Li
Pages: 1261-1272
Published online on: 12 January 2021

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Article

Expression of immune response biomarkers (PD‑L1, p16, CD3+ and CD8+ TILs) in recurrent head and neck squamous cell carcinoma within previously irradiated areas

Carole Pflumio, Jacques Thomas, Julia Salleron, Jean‑Christophe Faivre, Christian Borel, Gilles Dolivet, Xavier Sastre‑Garau, Lionnel Geoffrois
Pages: 1273-1283
Published online on: 07 January 2021

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Article

Acidic microenvironment induction of interleukin-8 expression and matrix metalloproteinase-2/-9 activation via acid-sensing ion channel 1 promotes breast cancer cell progression

Masako Nakanishi, Ayaka Korechika, Haruka Yamakawa, Naoko Kawabe, Kazuma Nakai, Yasuteru Muragaki
Pages: 1284-1294
Published online on: 24 December 2020

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Article

Role of ERCC5 polymorphisms in non‑small cell lung cancer risk and responsiveness/toxicity to cisplatin‑based chemotherapy in the Chinese population

Miao Li, Rong Chen, Baoyan Ji, Chunmei Fan, Guanying Wang, Chenli Yue, Guoquan Jin
Pages: 1295-1305
Published online on: 14 January 2021

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Article

Repurposing of a monoamine oxidase A inhibitor‑heptamethine carbocyanine dye conjugate for paclitaxel‑resistant non‑small cell lung cancer

Xiao‑Guang Yang, Yan‑Yu Li, Dong‑Xue Zhao, Wei Cui, Han Li, Xin‑Yu Li, Yu‑Xin Li, Dun Wang
Pages: 1306-1314
Published online on: 22 January 2021

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Correction Open Access

[Corrigendum] Exogenous hydrogen sulfide exerts proliferation, anti-apoptosis, migration effects and accelerates cell cycle progression in multiple myeloma cells via activating the Akt pathway

Dong Zheng, Ziang Chen, Jingfu Chen, Xiaomin Zhuang, Jianqiang Feng, Juan Li
Pages: 1315-1315
Published online on: 05 January 2021

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Correction Open Access

[Corrigendum] siRNA-mediated inhibition of endogenous brain‑derived neurotrophic factor gene modulates the biological behavior of HeLa cells

Chun-Yan Sun, Zhang-Bo Chu, Jing Huang, Lei Chen, Jian Xu, Ao-Shuang Xu, Jun-Ying Li, Yu Hu
Pages: 1316-1316
Published online on: 05 January 2021

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Journal Cover
January-2026 Volume 55 Issue 1

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Nabil Mouawad, Nour El Jaafari, Mirvat El Sibai, Ralph J. Abi-Habib
Article Number: 24
Published online on: 24 November 2025

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Expression of Concern Open Access

[Expression of Concern] Promoter methylation of death‑associated protein kinase and its role in irradiation response in cervical cancer

Rebecca Ching-Yu Leung, Stephanie Si Liu, Kelvin Yuen-Kwong Chan, Kar-Fai Tam, Kar-Loen Chan, Ling-Chui Wong, Hextan Yuen-Sheung Ngan
Article Number: 23
Published online on: 24 November 2025

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Article Open Access

Oxaliplatin resistance in pancreatic ductal adenocarcinoma is non‑significantly mediated by diminished drug uptake but is highly linked to a poor apoptotic response to the cytotoxic threat

Hellen Röttgen, Lana Theurer, Teresa Peccerella, Ketaki Sandu, Johanna Weiss, Jürgen Burhenne, John P. Neoptolemos, Beate Köberle, Dirk Theile
Article Number: 22
Published online on: 19 November 2025

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Correction Open Access

[Corrigendum] Src homology phosphotyrosyl phosphatase 2 mediates cisplatin‑related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells

Chunlan Tang, Hu Luo, Dan Luo, Heping Yang, Xiangdong Zhou
Article Number: 21
Published online on: 19 November 2025

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Article Open Access

S100B drives glioblastoma invasion and migration through TGF‑β2‑mediated epithelial‑mesenchymal transition

Xuemei Liao, Yuan Xu, Honghong Zhou, Qin Yi, Shifang Dong, Bin Tan
Article Number: 20
Published online on: 19 November 2025

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Review Open Access

Role of the SOX family in non‑small cell lung cancer: Molecular mechanisms and therapeutic implications (Review)

Kaiwei Wang, Yaoqi Li, Zhening Guo, Lin Song, Xiaoliang Ding, Linsheng Liu, Tao Hu, Yicong Bian, Chenrong Huang, Liyan Miao
Article Number: 19
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑18a enhances the radiosensitivity of cervical cancer cells by promoting radiation‑induced apoptosis

Sha Liu, Xiaofen Pan, Qin Yang, Lu Wen, Yao Jiang, Yingchao Zhao, Guiling Li
Article Number: 18
Published online on: 17 November 2025

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Review Open Access

Role of histone deacetylases in blood cancer: Exploring peptide‑based inhibitors as therapeutic strategies for leukemia treatment (Review)

Yaneenart Suwanwong, Phornthip Ploensil
Article Number: 17
Published online on: 14 November 2025

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Review Open Access

The multidimensional regulatory network of the PD‑1/PD‑L1 axis in the esophageal squamous cell carcinoma microenvironment: Implications for novel combination therapies and precision immunotherapy (Review)

Haoyue Lai, Lu Qi, Zhixuan Lin, Zhongwen Li
Article Number: 16
Published online on: 13 November 2025

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Review Open Access

From modification to malignancy: Bridging acetylation mechanisms and therapeutic innovations in melanoma (Review)

Jingwen Wu, Xuxia Cai, Zimo Zhu, Xiahong Li, Kaoyuan Zhang, Chenchen Wu, Bo Yu, Cong Huang
Article Number: 15
Published online on: 12 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑92b promotes tumor growth and activation of NF‑κB signaling via regulation of NLK in oral squamous cell carcinoma

Zhiming Liu, Cynthia Diep, Tiantian Mao, Li Huang, Robert Merrill, Zhouwen Zhang, Youjian Peng
Article Number: 14
Published online on: 11 November 2025

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Article Open Access

C‑terminal HSP90 inhibitor NCT‑58 impairs the cancer stem‑like phenotype and enhances chemotherapy efficacy in TNBC

Eunsun Jung, Yoon-Jae Kim, Kyoungmin Lee, Seojin Jang, Soeun Park, Eunhye Oh, Minsu Park, Seongjae Kim, Dongmi Ko, Yong Koo Kang, Kee Dal Nam, Lee Farrand, Cong-Truong Nguyen, Minh Thanh La, Jihyae Ann, Jeewoo Lee, Ji Young Kim, Jae Hong Seo
Article Number: 13
Published online on: 11 November 2025

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Correction Open Access

[Corrigendum] Compound 225# inhibits the proliferation of human colorectal cancer cells by promoting cell cycle arrest and apoptosis induction

Xiaoxue Zhang, Liujun He, Yong Li, Yifei Qiu, Wujing Hu, Wanying Lu, Huihui Du, Donglin Yang
Article Number: 12
Published online on: 06 November 2025

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Review Open Access

Immune system, inflammatory response, and regulated cell death in breast cancer research (Review)

Guangyao Li, Binghui Jin, Jialin Zhou, Shifeng Fang, Zhe Fan
Article Number: 11
Published online on: 05 November 2025

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Retraction Open Access

[Retracted] Uvangoletin induces mitochondria‑mediated apoptosis in HL‑60 cells in vitro and in vivo without adverse reactions of myelosuppression, leucopenia and gastrointestinal tract disturbances

Zhuanzhen Zheng, Zhenhua Qiao, Rong Gong, Yalin Wang, Yiqun Zhang, Yanping Ma, Li Zhang, Yujin Lu, Bo Jiang, Guoxia Li, Chunxia Dong, Wenliang Chen
Article Number: 10
Published online on: 03 November 2025

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Article Open Access

Characterization of the anticancer effect of mebendazole and its interaction with standard cytotoxic drugs in patient tumor cells ex vivo and in an in vivo mouse model

Sharmineh Mansoori, Kristin Blom, Claes Andersson, Mårten Fryknäs, Rolf Larsson, Peter Nygren
Article Number: 9
Published online on: 31 October 2025

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Correction Open Access

[Corrigendum] Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer

Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wang
Article Number: 8
Published online on: 30 October 2025

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Article Open Access

CD44 knockdown and TGF‑β inhibition modulate cell proliferation and invasion in claudin‑low breast cancer cells

Ryoichi Matsunuma, Kazuo Kinoshita, Sae Imada, Shoko Sato, Ryosuke Hayami, Michiko Tsuneizumi
Article Number: 7
Published online on: 30 October 2025

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Retraction Open Access

[Retracted] MicroRNA‑302a targets GAB2 to suppress cell proliferation, migration and invasion of glioma

Jiuhong Ma, Jia Yu, Jingmei Liu, Xing Yang, Miao Lou, Jinghui Liu, Fuqiang Feng, Peigang Ji, Liang Wang
Article Number: 6
Published online on: 27 October 2025

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Article Open Access

LRRC59 inhibits perk pathway‑induced apoptosis and promotes cell proliferation, migration and invasion in colorectal cancer cells

Xingdong Hou, Yuting Wang, Yuzhuo Chen, Peiyan Zhong, Guangzhi Wang, Baicheng Li, Bowei Lu, Hanyu Jiang, Shili Ning
Article Number: 5
Published online on: 23 October 2025

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Article Open Access

Comparative analysis of the efficacy and safety of antibody‑drug conjugates, radionuclide‑drug conjugates and their combination targeting claudin 18.2 in gastric cancer treatment

Huan Du, Xiao-Fei Hao, Bin-Wei Lin, Yu Zhang, Luo Rui, Jing Wang, Ming-Ming Tang, De-Cai Wang, Yi-Han Zhu, Jie Li, Tang-Zhi Dai, Yuchuan Yang, Xia Yang, Xiaobo Du
Article Number: 4
Published online on: 22 October 2025

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Expression of Concern Open Access

[Expression of Concern] CDKN3 is an independent prognostic factor and promotes ovarian carcinoma cell proliferation in ovarian cancer

Tianren Li, Hui Xue, Yi Guo, Kejun Guo
Article Number: 3
Published online on: 16 October 2025

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Review Open Access

Platelet‑circulating tumor cell crosstalk: A pivotal target in cancer diagnosis and therapy (Review)

Lifang Zhang, Ye Yuan, Yan Deng, Lin Wang, Fenghua Chen
Article Number: 2
Published online on: 15 October 2025

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Expression of Concern Open Access

[Expression of Concern] Knockdown of Bmi1 inhibits the stemness properties and tumorigenicity of human bladder cancer stem cell‑like side population cells

Dingjun Zhu, Xuesi Wan, Hai Huang, Xu Chen, Wu Liang, Fengjin Zhao, Tianxin Lin, Jinli Han, Wenlian Xie
Article Number: 1
Published online on: 14 October 2025

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Journal Cover
February-2026 Volume 55 Issue 2

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Journal Metrics

Impact Factor: 3.9

CiteScore: 8.3

CiteScore Rank: Q1: #73/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.786

SCImago Journal Rank (SJR): 0.915

Review Open Access

Alternative splicing in cancer drug resistance: Mechanisms and therapeutic prospects (Review)

Wenpu Zhu, Zikun Wu, Chai Luv, Banghe Bao, Weijie Zhao, Guanglong Chen, Hang Yang, Huihan Ai, Faqiang Liu, Zhi Li
Article Number: 31
Published online on: 05 December 2025

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Article Open Access

Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells

Liangliang Jin, Li Wei, Junrui Hua, Rong Zhang, Jiaxin Chen, Jinpeng He, Yanli Yang
Article Number: 30
Published online on: 04 December 2025

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Review

Beyond eradication: Therapeutic reprogramming strategies for cancer normalization (Review)

Aliasgar Shahiwala
Article Number: 29
Published online on: 04 December 2025

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Article Open Access

Saikosaponin D overcomes gemcitabine resistance in pancreatic cancer via AKT/mTOR pathway inhibition and synergistic induction of apoptosis and autophagy

Rui Zheng, Yusi Liu, Sen Zhou, Guimei Liu, Xiaobin Liu, Yiyuan Yang, Yufu Zhang
Article Number: 28
Published online on: 04 December 2025

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Retraction Open Access

[Retracted] Downregulation of Bmi‑1 is associated with suppressed tumorigenesis and induced apoptosis in CD44+ nasopharyngeal carcinoma cancer stem‑like cells

Xinhua Xu, Yang Liu, Jin Su, Daojun Li, Juan Hu, Qiao Huang, Mingqian Lu, Xiaoyan Liu, Jinghua Ren, Weihong Chen, Lidan Sun
Article Number: 27
Published online on: 04 December 2025

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Article Open Access

Prognostic significance of fibroblast senescence and senescence-associated secretory phenotype factor expression in the tumor microenvironment of pancreatic ductal adenocarcinoma

Yuto Kitano, Tomoharu Miyashita, Takeo Shimasaki, Isamu Makino, Yoshio Endo, Yasuhiko Yamamoto, Noriyuki Inaki, Shintaro Yagi
Article Number: 26
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Sp1‑CD147 positive feedback loop promotes the invasion ability of ovarian cancer

Jing Zhao, Wei Ye, Juan Wu, Lijuan Liu, Lina Yang, Lu Gao, Biliang Chen, Fanglin Zhang, Hong Yang, Yu Li
Article Number: 25
Published online on: 25 November 2025

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