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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2014 Volume 33 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Biodistribution of mesenchymal stem cell-derived extracellular vesicles in a model of acute kidney injury monitored by optical imaging

Cristina Grange, Marta Tapparo, Stefania Bruno, Devasis Chatterjee, Peter J. Quesenberry, Ciro Tetta, Giovanni Camussi
Pages: 1055-1063
Published online on: 20 February 2014

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Article Open Access

Intramuscular injection of adenoviral hepatocyte growth factor at a distal site ameliorates dextran sodium sulfate-induced colitis in mice

Kentaro Yuge, Tomoyuki Takahashi, Ngin Cin Khai, Kazuko Goto, Takako Fujiwara, Hisayoshi Fujiwara, Ken-Ichiro Kosai
Pages: 1064-1074
Published online on: 06 March 2014

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Article Open Access

Islet-1 promotes the cardiac-specific differentiation of mesenchymal stem cells through the regulation of histone acetylation

Naijing Yin, Rong Lu, Jianping Lin, Shenshen Zhi, Jie Tian, Jing Zhu
Pages: 1075-1082
Published online on: 06 March 2014

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Article Open Access

Proteasome inhibitor MG132 inhibits the proliferation and promotes the cisplatin-induced apoptosis of human esophageal squamous cell carcinoma cells

Lifeng Dang, Fengbiao Wen, Yang Yang, Donglei Liu, Kai Wu, Yu Qi, Xiangnan Li, Jia Zhao, Dengyan Zhu, Chunyang Zhang, Song Zhao
Pages: 1083-1088
Published online on: 27 February 2014

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Article Open Access

The PI3K/Akt signaling pathway exerts effects on the implantation of mouse embryos by regulating the expression of RhoA

Liyuan Liu, Yingxiong Wang, Qiubo Yu
Pages: 1089-1096
Published online on: 17 March 2014

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Article Open Access

Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis

Zhaorui Sun, Cong Wang, Chaowen Shi, Fangfang Sun, Xiaomeng Xu, Weiping Qian, Shinan Nie, Xiaodong Han
Pages: 1097-1109
Published online on: 25 February 2014

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Article Open Access

Differential expression of apoptosis-related factors induces the age-related apoptosis of the gracilis muscle in humans

Soo Yeon Park, Jung Hwan Lee, Ha Young Kim, Kyoung Ho Yoon, Seong Kyu Park, Mun Seog Chang
Pages: 1110-1116
Published online on: 27 February 2014

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Article Open Access

Identification of differentially expressed microRNAs in metastatic melanoma using next-generation sequencing technology

Min Qi, Xiaoyuan Huang, Lei Zhou, Jianglin Zhang
Pages: 1117-1121
Published online on: 25 February 2014

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Article Open Access

Plexin-A1 is required for Toll-like receptor‑mediated microglial activation in the development of lipopolysaccharide-induced encephalopathy

Takuji Ito, Kenji Yoshida, Takayuki Negishi, Masayasu Miyajima, Hyota Takamatsu, Hitoshi Kikutani, Atsushi Kumanogoh, Kazunori Yukawa
Pages: 1122-1130
Published online on: 07 March 2014

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Article

Effects of phased joint intervention on IL-35 and IL-17 expression levels in patients with portal hypertension

Yugang Wang, Jinbin Dong, Wenying Meng, Jiali Ma, Na Wang, Jue Wei, Min Shi
Pages: 1131-1139
Published online on: 19 February 2014

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Article

Inhibitory effects of Pericarpium zanthoxyli extract on adipocyte differentiation

Ha-Rim Kim, Jeong-Mi Kim, Mi-Seong Kim, Jin-Ki Hwang, Sei-Hoon Yang, Hye-Jung Kim, Dong-Sung Lee, Hyuncheol Oh, Youn-Chul Kim, Do-Gon Ryu, Young-Rae Lee, Kang-Beom Kwon
Pages: 1140-1146
Published online on: 25 February 2014

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Article

Recombinant growth factor mixtures induce cell cycle progression and the upregulation of type I collagen in human skin fibroblasts, resulting in the acceleration of wound healing processess

Do Hyun Lee, Kyung-Ha Choi, Jae-We Cho, So Young Kim, Tae Rin Kwon, Sun Young Choi, Yoo Mi Choi, Jay Lee, Ho Sang Yoon, Beom Joon Kim
Pages: 1147-1152
Published online on: 14 March 2014

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Article

RASSF1A promotes apoptosis and suppresses the proliferation of ovarian cancer cells

Lingjie Fu, Shulan Zhang
Pages: 1153-1160
Published online on: 25 February 2014

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Article

Inhibitory effects of resveratrol on foam cell formation are mediated through monocyte chemotactic protein-1 and lipid metabolism-related proteins

Wenpeng Dong, Xianyue Wang, Shenghui Bi, Zhiguo Pan, Shenxi Liu, Hao Yu, Hua Lu, Xi Lin, Xiaowu Wang, Tao Ma, Weida Zhang
Pages: 1161-1168
Published online on: 28 February 2014

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Article

Farnesol induces apoptosis of DU145 prostate cancer cells through the PI3K/Akt and MAPK pathways

Jin Soo Park, Jung Ki Kwon, Hye Ri Kim, Hyeong Jin Kim, Byeong Soo Kim, Ji Youn Jung
Pages: 1169-1176
Published online on: 27 February 2014

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Article

1,25-Dihydroxyvitamin D3 and cisplatin synergistically induce apoptosis and cell cycle arrest in gastric cancer cells

Anyu Bao, Yan Li, Yongqing Tong, Hongyun Zheng, Wei Wu, Chuandong Wei
Pages: 1177-1184
Published online on: 24 February 2014

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Article

Quantitative evaluation of the therapeutic effect of fermented soybean products containing a high concentration of GABA on phthalic anhydride-induced atopic dermatitis in IL-4/Luc/CNS-1 Tg mice

Young Ju Lee, Ji Eun Kim, Moon Hwa Kwak, Jun Go, Dong Seob Kim, Hong Joo Son, Dae Youn Hwang
Pages: 1185-1194
Published online on: 06 March 2014

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Article

Differentially expressed microRNAs in TGFβ2-induced epithelial-mesenchymal transition in retinal pigment epithelium cells

Xiaoyun Chen, Shaobi Ye, Wei Xiao, Lixia Luo, Yizhi Liu
Pages: 1195-1200
Published online on: 07 March 2014

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Article

Novel PITX2c loss-of-function mutations associated with complex congenital heart disease

Dong Wei, Xiao-Hui Gong, Gang Qiu, Juan Wang, Yi-Qing Yang
Pages: 1201-1208
Published online on: 07 March 2014

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Article

Identification of suitable reference genes for quantitative RT-PCR during 3T3-L1 adipocyte differentiation

Juan Zhang, Hongju Tang, Yuqing Zhang, Ruyuan Deng, Li Shao, Yun Liu, Fengying Li, Xiao Wang, Libin Zhou
Pages: 1209-1218
Published online on: 11 March 2014

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Article

GATA5 loss-of-function mutations associated with congenital bicuspid aortic valve

Lin-Mei Shi, Ju-Wei Tao, Xing-Biao Qiu, Juan Wang, Fang Yuan, Lei Xu, Hua Liu, Ruo-Gu Li, Ying-Jia Xu, Qian Wang, Hong-Zhen Zheng, Xin Li, Xiao-Zhou Wang, Min Zhang, Xin-Kai Qu, Yi-Qing Yang
Pages: 1219-1226
Published online on: 14 March 2014

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Article

Somatic GATA5 mutations in sporadic tetralogy of Fallot

Ri-Tai Huang, Song Xue, Ying-Jia Xu, Min Zhou, Yi-Qing Yang
Pages: 1227-1235
Published online on: 26 February 2014

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Article

Inactivation of von Hippel-Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR-210/VMP1 signaling pathway

Ting Liu, Le Zhao, Wei Chen, Zhen Li, Huilian Hou, Lu Ding, Xu Li
Pages: 1236-1242
Published online on: 18 February 2014

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Article

miRNA profiling reveals a potential role of milk stasis in breast carcinogenesis

Yi-Qi Gu, Gu Gong, Zhe-Li Xu, Li-Ying Wang, Ming-Li Fang, Hui Zhou, Hua Xing, Ke-Ren Wang, Liang Sun
Pages: 1243-1249
Published online on: 27 February 2014

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Article

microRNA expression profiling of heart tissue during fetal development

Jizi Zhou, Xinran Dong, Qiongjie Zhou, Huijun Wang, Yanyan Qian, Weidong Tian, Duan Ma, Xiaotian Li
Pages: 1250-1260
Published online on: 07 March 2014

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Article

Parthenolide exerts inhibitory effects on angiogenesis through the downregulation of VEGF/VEGFRs in colorectal cancer

Se-Lim Kim, Soo-Teik Lee, Kieu Thi Thu Trang, Seong Hun Kim, In Hee Kim, Seung Ok Lee, Dae Ghon Kim, Sang-Wook Kim
Pages: 1261-1267
Published online on: 25 February 2014

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Article

Flap endonuclease 1 is a promising candidate biomarker in gastric cancer and is involved in cell proliferation and apoptosis

Kejia Wang, Chunhong Xie, Daorong Chen
Pages: 1268-1274
Published online on: 28 February 2014

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Article

Inhibition of high glucose-induced apoptosis by uncoupling protein 2 in human umbilical vein endothelial cells

Ying He, Ning Wang, Yinchen Shen, Zhi Zheng, Xun Xu
Pages: 1275-1281
Published online on: 27 February 2014

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Article

Fluid flow modulates the expression of genes involved in the Wnt signaling pathway in osteoblasts in 3D culture conditions

Yuan-Yuan Jia, Feng Li, Ning Geng, Ping Gong, Shi-Jie Huang, Ling-Xian Meng, Jing Lan, Yu Ban
Pages: 1282-1288
Published online on: 11 March 2014

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Article

Detection of hTERC and c-MYC genes in cervical epithelial exfoliated cells for cervical cancer screening

Tian Li, Liangdan Tang, Duhong Bian, Ying Jia, Xin Huang, Xinhua Zhang
Pages: 1289-1297
Published online on: 14 March 2014

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Article

Colistin-induced apoptosis in PC12 cells: Involvement of the mitochondrial apoptotic and death receptor pathways

Hong Jiang, Jichang Li, Tiezhong Zhou, Chunhua Wang, Hua Zhang, Hongjun Wang
Pages: 1298-1304
Published online on: 06 March 2014

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Article

The effect of zipper‑interacting protein kinase on high glucose‑stimulated human aortic smooth muscle cells

Zi Ye, Wei Wu, Min He, Mancheong Leong, Renming Hu, Yiming Li, Shuo Zhang
Pages: 1305-1311
Published online on: 14 March 2014

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Article

Identification of peptides that bind hepatitis C virus envelope protein E2 and inhibit viral cellular entry from a phage-display peptide library

Xin Lü, Min Yao, Jian-Min Zhang, Jing Yang, Ying-Feng Lei, Xiao-Jun Huang, Zhan-Sheng Jia, Li Ma, Hai-Yun Lan, Zhi-Kai Xu, Wen Yin
Pages: 1312-1318
Published online on: 25 February 2014

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Article

High expression of the secreted protein dickkopf homolog 4: Roles in invasion and metastasis of renal cell carcinoma and its association with Von Hippel-Lindau gene Corrigendum in /10.3892/ijmm.2023.5250

Wei Zhai, Guang-Hui Hu, Jun-Hua Zheng, Bo Peng, Min Liu, Jian‑Hua Huang, Guang-Chun Wang, Xu-Dong Yao, Yun-Fei Xu
Pages: 1319-1326
Published online on: 25 February 2014

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Article

Protective effect of apigenin against oxidative stress-induced damage in osteoblastic cells

Woon-Won Jung
Pages: 1327-1334
Published online on: 25 February 2014

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Article

Tetrandrine suppresses pro-inflammatory mediators in PMA plus A23187-induced HMC-1 cells

Ok-Hwa Kang, Hyeon-Jin An, Sung-Bae Kim, Su-Hyun Mun, Yun-Soo Seo, Dae-Ki Joung, Jang-Gi Choi, Dong-Won Shin, Dong-Yeul Kwon
Pages: 1335-1340
Published online on: 04 March 2014

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Article

Oxidized low-density lipoprotein increases the proliferation and migration of human coronary artery smooth muscle cells through the upregulation of osteopontin

Jun Liu, Yingang Ren, Li Kang, Lihua Zhang
Pages: 1341-1347
Published online on: 28 February 2014

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Article

Mangiferin increases Nrf2 protein stability by inhibiting its ubiquitination and degradation in human HL60 myeloid leukemia cells

Jie Zhao, Benping Zhang, Shanshan Li, Linglan Zeng, Yan Chen, Jun Fang
Pages: 1348-1354
Published online on: 12 March 2014

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Article

Identification of hypo- and hypermethylated genes related to atherosclerosis by a genome-wide analysis of DNA methylation

Yoshiji Yamada, Tamotsu Nishida, Hideki Horibe, Mitsutoshi Oguri, Kimihiko Kato, Motoji Sawabe
Pages: 1355-1340
Published online on: 10 March 2014

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Article

SOCS3 and SOCS6 are required for the risperidone-mediated inhibition of insulin and leptin signaling in neuroblastoma cells

Longzhen Piao, Jisoo Park, Yuwen Li, Sanghee Shin, Soyeon Shin, Gyeyeong Kong, Robin Shrestha, Quangdon Tran, Gang Min Hur, Jeong-Lan Kim, Jongsun Park
Pages: 1364-1370
Published online on: 10 March 2014

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Correction Open Access

[Erratum] Differential effect of statins on diabetic nephropathy in db/db mice

Yukinori Tamura, Toshinori Murayama, Manabu Minami, Masayuki Yokode, Hidenori Arai
Pages: 1371-1371
Published online on: 24 February 2014

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Journal Cover
January-2026 Volume 57 Issue 1

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

FK506‑binding proteins as emerging bridges linking proteostasis to multi‑system pathogenesis and therapeutic strategies (Review)

Zhi Li, Xiaolei Liu, Hesong Zeng
Article Number: 30
Published online on: 24 November 2025

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Retraction Open Access

[Retracted] Suppression of SIK1 by miR‑141 in human ovarian cancer cell lines and tissues

Jin-Long Chen, Fang Chen, Ting-Ting Zhang, Nai-Fu Liu
Article Number: 29
Published online on: 24 November 2025

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METTL3 inhibits LINC00312 to suppress osteoporosis progression in a YTHDF2‑dependent manner

Yang Wang, Yihao Tian, Gang Yao
Article Number: 28
Published online on: 20 November 2025

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Review Open Access

Decoding structural birth defects through genomic landscapes: Innovative frameworks for diagnosis (Review)

Ruihao Xu, Haoming Ren, Zhengwei Yuan, Wanqi Huang, Hui Gu
Article Number: 27
Published online on: 20 November 2025

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MOTS‑c protects against placental injury via Nrf2 activation in hypoxia‑induced intrauterine growth restriction mice

Dan Chen, Hui-Min Zhao, Xiao-Lin Sun, Zhi-Xuan Xing, Sheng-Peng Li, Shuai-Chao Li, Ya-Xian Wu, Qing-Feng Pang, Jian-Feng Huang
Article Number: 26
Published online on: 18 November 2025

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Synergistic effects of Akebia saponin D and Semaglutide on diabetic nephropathy and osteoporosis via the Klotho‑p53 signaling axis

Qian Zhang, Dan Wang, Hongxia Jia, Zongji Zheng, Liyan Lin, Linna Li, Ling Wang, Yaoming Xue
Article Number: 25
Published online on: 18 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑103 modulates tumor progression by targeting KLF7 in non‑small cell lung cancer

Ke Li, Conghu Yuan
Article Number: 24
Published online on: 17 November 2025

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Article

Comparative analysis of pan MHC‑I epitopes immunoreactivity on Hantaan virus nucleocapsid protein

Zhikui Li, Weijie Ding, Yubo Sun, Chenfeng Tian, Shuaishuai Fu, Fei Shi, Zhenchi Fang, Yuanzhe Li, Jianchang Li, Sirui Cai, Haobo Kang, Baozeng Sun, Junqi Zhang, Yuanjie Sun, Shuya Yang, Yusi Zhang, Chunmei Zhang, Yun Zhang, Xiyang Zhang, Kun Yang, Dongbo Jiang
Article Number: 23
Published online on: 14 November 2025

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Article Open Access

Human papillomavirus E7 inhibits immune responses in keratinocytes by activating HTRA1‑mediated mitophagy

Boya Zhang, Defeng Kong, Siji Chen, Xuewu Sun, Hao Cheng
Article Number: 22
Published online on: 14 November 2025

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Targeting p38 MAPK signaling pathway: 
Quercetin as a novel therapy for TMJ synovitis

Mosha Cheng, Yuhe Guan, Xiaotao Xin, Xin Yi, Yi Liu
Article Number: 21
Published online on: 13 November 2025

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Review Open Access

Lipid droplets in astrocytes: Key organelles for CNS homeostasis and disease (Review)

Yuchen Wang, Boxuan Wang, Jinchao Hou, Xiaodong Huo, Chenlin Liu, Ruili Guan, Honggang Chen, Yang Zhou, Jianbin Zhang, Congcong Zhuang, Yuankang Zou
Article Number: 20
Published online on: 13 November 2025

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Copper dyshomeostasis and cardiovascular disease: Molecular mechanisms and new strategies for targeted intervention with cuproptosis (Review)

Peiyu Li, Yinghui Li, Qian Meng, Jie Wang, Kun Wang, Sumin Yang
Article Number: 19
Published online on: 13 November 2025

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Elevated FTO alleviates sepsis‑induced acute kidney injury by regulating macrophage inflammatory phenotypes

Xiaona Chen, Ziqi Sun, Jiabo Chen, Jinquan Zhang, Zeyu Liu, Zhengzheng Yan, Quan Li, Zhixia Chen
Article Number: 18
Published online on: 12 November 2025

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Correction Open Access

[Corrigendum]  Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

Bo Meng, Yisong Wang, Bin Li
Article Number: 17
Published online on: 10 November 2025

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Microbial short chain fatty acids: Effective histone deacetylase inhibitors in immune regulation (Review)

Jing Wang, Qin Zhao, Shuwan Zhang, Jia Liu, Xingyue Fan, Bin Han, Yaqin Hou, Xiaopeng Ai
Article Number: 16
Published online on: 05 November 2025

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High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review)

Min You, Fan Wu, Feng Xiong, Xue-Fei Hu, Huan Wu, Li Zhou, Hong-Xing Zhang
Article Number: 15
Published online on: 05 November 2025

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ROCK inhibition promotes axon and myelin regeneration via PI3K/Akt/GSK3β in a mouse sciatic nerve injury model

Shuang Dou, Zhijun Li, Boyao Zheng, Zhenyu Ren, Hai Wang, Qing Zuo, Fang Fang, Yuehong Zhuang
Article Number: 14
Published online on: 05 November 2025

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Mechanisms of mTORC1 and GCN2 amino acid sensing pathways in tumorigenesis and metastatic progression (Review)

Chaowei Zhang, Yuxuan Han, Weiyi Yao, Qing Hong, Na Chen
Article Number: 13
Published online on: 04 November 2025

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Review Open Access

β‑hydroxybutyric acid as a potential therapeutic metabolite for type 2 diabetes mellitus (Review)

Xianyi Ding, Jiabin Wu, Lian Wang, Ke Li, Haoyang Gao, Mingyu Wu, Qiuyu Zhang, Ruonan Han, Wenhong Wang, Weihua Xiao
Article Number: 12
Published online on: 03 November 2025

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Review

Histone lactylation: Unveiling a novel pathway for the impact of lactate on physiological and pathological processes (Review)

Xunjie Jian, Chang Cheng, Wenjie Lu, Hui Peng, Diqi Yang
Article Number: 11
Published online on: 03 November 2025

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Review Open Access

Interpretation of the molecular mechanism and therapeutic potential of microRNA‑155 in cardiovascular and cerebrovascular diseases (Review)

Xitong Zhao, Pengqin Wang
Article Number: 10
Published online on: 03 November 2025

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Expression of Concern Open Access

[Expression of Concern]  CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 9
Published online on: 29 October 2025

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Article Open Access

TWEAK modulates the characteristics of periodontal ligament stem cells via the Fn14/NF‑κB pathway

Linlin Xiao, Man Qu, Lulu Chen, Mingli Xiang, Qian Long, Jianguo Liu, Xiaoyan Guan, Chengcheng Liao
Article Number: 8
Published online on: 27 October 2025

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Review Open Access

Harnessing copper: Innovative approaches to combat neurodegenerative diseases and cancer (Review)

Tao Duan, Hanhai Mao, Xingyue Jiang, Ying Tian, Jidong Zhang, Jun Tan
Article Number: 7
Published online on: 27 October 2025

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Retraction Open Access

[Retracted] Effects of miR‑106b‑3p on cell proliferation and epithelial‑mesenchymal transition, and targeting of ZNRF3 in esophageal squamous cell carcinoma

Guanen Qiao, Chenguang Dai, Yang He, Junjie Shi, Chunfang Xu
Article Number: 6
Published online on: 27 October 2025

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Review Open Access

Immune and metabolic remodeling following bariatric surgery: Implications for targeted immunotherapy (Review)

Yiming Shao, Ke Song, Ruixin Yu, He Xiao, Chengjun Li, Yuling Deng, Yuan Zhang, Yixing Ren
Article Number: 5
Published online on: 24 October 2025

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Article Open Access

Exportin 1 inhibitor KPT‑330 reverses oxaliplatin resistance via p53 nuclear retention in colorectal cancer

Chuanxi Lai, Xiya Jia, Yiyi Chen, Kangke Chen, Fei Wang, Qiqi Zhang, Xiaonan Xiang, Zhe-Sheng Chen, Lingna Xu, Sheng Dai
Article Number: 4
Published online on: 23 October 2025

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Article Open Access

Targeting of CIRP attenuates osteoarthritis progression via suppressing TLR4/NF‑κB/NLRP3 signaling axis

Weichao Sun, Yi Liao, Jianguo Feng, Jianhui Liang, Qifei He, Yinxing Cui, Dixi Huang, Houyin Shi, Wei You, Wei Sun, Qian Yi
Article Number: 3
Published online on: 23 October 2025

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Review

Importance of B cells (Review)

Zhiyuan Liu, Haoran Dai, Xiaoyu Cui, Yeping Liu, Zhaocheng Dong
Article Number: 2
Published online on: 22 October 2025

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Retraction Open Access

[Retracted] Hypoxic preconditioned bone mesenchymal stem cells ameliorate spinal cord injury in rats via improved survival and migration

Weiheng Wang, Xiaodong Huang, Wenbo Lin, Yuanyuan Qiu, Yunfei He, Jiangming Yu, Yanhai Xi, Xiaojian Ye
Article Number: 1
Published online on: 22 October 2025

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Journal Cover
February-2026 Volume 57 Issue 2

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

STOML2 interacts with PHB to activate the MEK/ERK signaling pathway and mediates autophagy‑related proteins in the progression of hepatocellular carcinoma

Haoyang Hu, Haozhe Zhang, Shuai Han, Jianli Chen, Ying Xie
Article Number: 38
Published online on: 04 December 2025

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Article Open Access

HMGB1 mediates low-dose ionizing radiation-induced Wnt/β-catenin activation in SRA01/04 cells: Mechanistic clues to early cataractogenesis

Ping Wang, Chunnan Piao, Dong Yan, Yingxue He, Yaru Li, Li Fan, Mei Tian
Article Number: 37
Published online on: 04 December 2025

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Article Open Access

FBXO22 promotes hepatocellular carcinoma progression via paracrine myo‑inositol‑induced M2‑type polarization of macrophages

Liangliang Bai, Jing Xiong, Sihai Chen, Jiahao Hu, Meixia Zhang, Bimin Li, Jing Hu, Mingyan He
Article Number: 36
Published online on: 02 December 2025

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Review Open Access

Branched‑chain amino acid metabolism and bone metabolism: Implications for osteoporosis pathogenesis and therapeutic strategies (Review)

Qi Xiao, Haimin Zeng, Ruhui Yang, Yuxin Zhan, Fangzhen Lin, Bofan Chen, Xiang Chen
Article Number: 35
Published online on: 02 December 2025

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Review Open Access

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Yan Wang, Baowei Feng, Yanting Wu, Zongle Sun, Hao Yuan, Wei Chen, Chang Zhao, Zhi Liu
Article Number: 34
Published online on: 02 December 2025

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Review Open Access

Role of matrix metalloproteinases in the invasion of glioblastoma and drug interventions (Review)

Bohao Zheng, Ying Han, Haiying Zhang
Article Number: 33
Published online on: 01 December 2025

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Review

Bridging bench to bedside: Exosome‑based strategies for endometriosis diagnosis and treatment (Review)

Wanmeng Chen, Yujiu Ma, Xudong Zhang, Siwen Zhang, Shanshan Wu, Yimeng Lu, Jichun Tan
Article Number: 32
Published online on: 01 December 2025

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Retraction Open Access

[Retracted] miR‑381 functions as a tumor suppressor by targeting ETS1 in pancreatic cancer

Guanen Qiao, Jing Li, Jun Wang, Zhaoyang Wang, Wei Bian
Article Number: 31
Published online on: 01 December 2025

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