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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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International Journal of Molecular Medicine

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2014 Volume 33 Issue 5

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Biodistribution of mesenchymal stem cell-derived extracellular vesicles in a model of acute kidney injury monitored by optical imaging

Cristina Grange, Marta Tapparo, Stefania Bruno, Devasis Chatterjee, Peter J. Quesenberry, Ciro Tetta, Giovanni Camussi
Pages: 1055-1063
Published online on: 20 February 2014

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Article Open Access

Intramuscular injection of adenoviral hepatocyte growth factor at a distal site ameliorates dextran sodium sulfate-induced colitis in mice

Kentaro Yuge, Tomoyuki Takahashi, Ngin Cin Khai, Kazuko Goto, Takako Fujiwara, Hisayoshi Fujiwara, Ken-Ichiro Kosai
Pages: 1064-1074
Published online on: 06 March 2014

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Article Open Access

Islet-1 promotes the cardiac-specific differentiation of mesenchymal stem cells through the regulation of histone acetylation

Naijing Yin, Rong Lu, Jianping Lin, Shenshen Zhi, Jie Tian, Jing Zhu
Pages: 1075-1082
Published online on: 06 March 2014

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Article Open Access

Proteasome inhibitor MG132 inhibits the proliferation and promotes the cisplatin-induced apoptosis of human esophageal squamous cell carcinoma cells

Lifeng Dang, Fengbiao Wen, Yang Yang, Donglei Liu, Kai Wu, Yu Qi, Xiangnan Li, Jia Zhao, Dengyan Zhu, Chunyang Zhang, Song Zhao
Pages: 1083-1088
Published online on: 27 February 2014

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Article Open Access

The PI3K/Akt signaling pathway exerts effects on the implantation of mouse embryos by regulating the expression of RhoA

Liyuan Liu, Yingxiong Wang, Qiubo Yu
Pages: 1089-1096
Published online on: 17 March 2014

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Article Open Access

Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis Corrigendum in /10.3892/ijmm.2026.5867

Zhaorui Sun, Cong Wang, Chaowen Shi, Fangfang Sun, Xiaomeng Xu, Weiping Qian, Shinan Nie, Xiaodong Han
Pages: 1097-1109
Published online on: 25 February 2014

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Article Open Access

Differential expression of apoptosis-related factors induces the age-related apoptosis of the gracilis muscle in humans

Soo Yeon Park, Jung Hwan Lee, Ha Young Kim, Kyoung Ho Yoon, Seong Kyu Park, Mun Seog Chang
Pages: 1110-1116
Published online on: 27 February 2014

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Article Open Access

Identification of differentially expressed microRNAs in metastatic melanoma using next-generation sequencing technology

Min Qi, Xiaoyuan Huang, Lei Zhou, Jianglin Zhang
Pages: 1117-1121
Published online on: 25 February 2014

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Article Open Access

Plexin-A1 is required for Toll-like receptor‑mediated microglial activation in the development of lipopolysaccharide-induced encephalopathy

Takuji Ito, Kenji Yoshida, Takayuki Negishi, Masayasu Miyajima, Hyota Takamatsu, Hitoshi Kikutani, Atsushi Kumanogoh, Kazunori Yukawa
Pages: 1122-1130
Published online on: 07 March 2014

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Article

Effects of phased joint intervention on IL-35 and IL-17 expression levels in patients with portal hypertension

Yugang Wang, Jinbin Dong, Wenying Meng, Jiali Ma, Na Wang, Jue Wei, Min Shi
Pages: 1131-1139
Published online on: 19 February 2014

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Article

Inhibitory effects of Pericarpium zanthoxyli extract on adipocyte differentiation

Ha-Rim Kim, Jeong-Mi Kim, Mi-Seong Kim, Jin-Ki Hwang, Sei-Hoon Yang, Hye-Jung Kim, Dong-Sung Lee, Hyuncheol Oh, Youn-Chul Kim, Do-Gon Ryu, Young-Rae Lee, Kang-Beom Kwon
Pages: 1140-1146
Published online on: 25 February 2014

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Article

Recombinant growth factor mixtures induce cell cycle progression and the upregulation of type I collagen in human skin fibroblasts, resulting in the acceleration of wound healing processess

Do Hyun Lee, Kyung-Ha Choi, Jae-We Cho, So Young Kim, Tae Rin Kwon, Sun Young Choi, Yoo Mi Choi, Jay Lee, Ho Sang Yoon, Beom Joon Kim
Pages: 1147-1152
Published online on: 14 March 2014

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Article

RASSF1A promotes apoptosis and suppresses the proliferation of ovarian cancer cells

Lingjie Fu, Shulan Zhang
Pages: 1153-1160
Published online on: 25 February 2014

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Article

Inhibitory effects of resveratrol on foam cell formation are mediated through monocyte chemotactic protein-1 and lipid metabolism-related proteins

Wenpeng Dong, Xianyue Wang, Shenghui Bi, Zhiguo Pan, Shenxi Liu, Hao Yu, Hua Lu, Xi Lin, Xiaowu Wang, Tao Ma, Weida Zhang
Pages: 1161-1168
Published online on: 28 February 2014

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Article

Farnesol induces apoptosis of DU145 prostate cancer cells through the PI3K/Akt and MAPK pathways

Jin Soo Park, Jung Ki Kwon, Hye Ri Kim, Hyeong Jin Kim, Byeong Soo Kim, Ji Youn Jung
Pages: 1169-1176
Published online on: 27 February 2014

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Article

1,25-Dihydroxyvitamin D3 and cisplatin synergistically induce apoptosis and cell cycle arrest in gastric cancer cells

Anyu Bao, Yan Li, Yongqing Tong, Hongyun Zheng, Wei Wu, Chuandong Wei
Pages: 1177-1184
Published online on: 24 February 2014

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Article

Quantitative evaluation of the therapeutic effect of fermented soybean products containing a high concentration of GABA on phthalic anhydride-induced atopic dermatitis in IL-4/Luc/CNS-1 Tg mice

Young Ju Lee, Ji Eun Kim, Moon Hwa Kwak, Jun Go, Dong Seob Kim, Hong Joo Son, Dae Youn Hwang
Pages: 1185-1194
Published online on: 06 March 2014

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Article

Differentially expressed microRNAs in TGFβ2-induced epithelial-mesenchymal transition in retinal pigment epithelium cells

Xiaoyun Chen, Shaobi Ye, Wei Xiao, Lixia Luo, Yizhi Liu
Pages: 1195-1200
Published online on: 07 March 2014

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Article

Novel PITX2c loss-of-function mutations associated with complex congenital heart disease

Dong Wei, Xiao-Hui Gong, Gang Qiu, Juan Wang, Yi-Qing Yang
Pages: 1201-1208
Published online on: 07 March 2014

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Article

Identification of suitable reference genes for quantitative RT-PCR during 3T3-L1 adipocyte differentiation

Juan Zhang, Hongju Tang, Yuqing Zhang, Ruyuan Deng, Li Shao, Yun Liu, Fengying Li, Xiao Wang, Libin Zhou
Pages: 1209-1218
Published online on: 11 March 2014

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Article

GATA5 loss-of-function mutations associated with congenital bicuspid aortic valve

Lin-Mei Shi, Ju-Wei Tao, Xing-Biao Qiu, Juan Wang, Fang Yuan, Lei Xu, Hua Liu, Ruo-Gu Li, Ying-Jia Xu, Qian Wang, Hong-Zhen Zheng, Xin Li, Xiao-Zhou Wang, Min Zhang, Xin-Kai Qu, Yi-Qing Yang
Pages: 1219-1226
Published online on: 14 March 2014

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Article

Somatic GATA5 mutations in sporadic tetralogy of Fallot

Ri-Tai Huang, Song Xue, Ying-Jia Xu, Min Zhou, Yi-Qing Yang
Pages: 1227-1235
Published online on: 26 February 2014

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Article

Inactivation of von Hippel-Lindau increases ovarian cancer cell aggressiveness through the HIF1α/miR-210/VMP1 signaling pathway

Ting Liu, Le Zhao, Wei Chen, Zhen Li, Huilian Hou, Lu Ding, Xu Li
Pages: 1236-1242
Published online on: 18 February 2014

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Article

miRNA profiling reveals a potential role of milk stasis in breast carcinogenesis

Yi-Qi Gu, Gu Gong, Zhe-Li Xu, Li-Ying Wang, Ming-Li Fang, Hui Zhou, Hua Xing, Ke-Ren Wang, Liang Sun
Pages: 1243-1249
Published online on: 27 February 2014

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Article

microRNA expression profiling of heart tissue during fetal development

Jizi Zhou, Xinran Dong, Qiongjie Zhou, Huijun Wang, Yanyan Qian, Weidong Tian, Duan Ma, Xiaotian Li
Pages: 1250-1260
Published online on: 07 March 2014

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Article

Parthenolide exerts inhibitory effects on angiogenesis through the downregulation of VEGF/VEGFRs in colorectal cancer

Se-Lim Kim, Soo-Teik Lee, Kieu Thi Thu Trang, Seong Hun Kim, In Hee Kim, Seung Ok Lee, Dae Ghon Kim, Sang-Wook Kim
Pages: 1261-1267
Published online on: 25 February 2014

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Article

Flap endonuclease 1 is a promising candidate biomarker in gastric cancer and is involved in cell proliferation and apoptosis

Kejia Wang, Chunhong Xie, Daorong Chen
Pages: 1268-1274
Published online on: 28 February 2014

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Article

Inhibition of high glucose-induced apoptosis by uncoupling protein 2 in human umbilical vein endothelial cells

Ying He, Ning Wang, Yinchen Shen, Zhi Zheng, Xun Xu
Pages: 1275-1281
Published online on: 27 February 2014

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Article

Fluid flow modulates the expression of genes involved in the Wnt signaling pathway in osteoblasts in 3D culture conditions

Yuan-Yuan Jia, Feng Li, Ning Geng, Ping Gong, Shi-Jie Huang, Ling-Xian Meng, Jing Lan, Yu Ban
Pages: 1282-1288
Published online on: 11 March 2014

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Article

Detection of hTERC and c-MYC genes in cervical epithelial exfoliated cells for cervical cancer screening

Tian Li, Liangdan Tang, Duhong Bian, Ying Jia, Xin Huang, Xinhua Zhang
Pages: 1289-1297
Published online on: 14 March 2014

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Article

Colistin-induced apoptosis in PC12 cells: Involvement of the mitochondrial apoptotic and death receptor pathways

Hong Jiang, Jichang Li, Tiezhong Zhou, Chunhua Wang, Hua Zhang, Hongjun Wang
Pages: 1298-1304
Published online on: 06 March 2014

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Article

The effect of zipper‑interacting protein kinase on high glucose‑stimulated human aortic smooth muscle cells

Zi Ye, Wei Wu, Min He, Mancheong Leong, Renming Hu, Yiming Li, Shuo Zhang
Pages: 1305-1311
Published online on: 14 March 2014

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Article

Identification of peptides that bind hepatitis C virus envelope protein E2 and inhibit viral cellular entry from a phage-display peptide library

Xin Lü, Min Yao, Jian-Min Zhang, Jing Yang, Ying-Feng Lei, Xiao-Jun Huang, Zhan-Sheng Jia, Li Ma, Hai-Yun Lan, Zhi-Kai Xu, Wen Yin
Pages: 1312-1318
Published online on: 25 February 2014

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Article

High expression of the secreted protein dickkopf homolog 4: Roles in invasion and metastasis of renal cell carcinoma and its association with Von Hippel-Lindau gene Corrigendum in /10.3892/ijmm.2023.5250

Wei Zhai, Guang-Hui Hu, Jun-Hua Zheng, Bo Peng, Min Liu, Jian‑Hua Huang, Guang-Chun Wang, Xu-Dong Yao, Yun-Fei Xu
Pages: 1319-1326
Published online on: 25 February 2014

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Article

Protective effect of apigenin against oxidative stress-induced damage in osteoblastic cells

Woon-Won Jung
Pages: 1327-1334
Published online on: 25 February 2014

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Article

Tetrandrine suppresses pro-inflammatory mediators in PMA plus A23187-induced HMC-1 cells

Ok-Hwa Kang, Hyeon-Jin An, Sung-Bae Kim, Su-Hyun Mun, Yun-Soo Seo, Dae-Ki Joung, Jang-Gi Choi, Dong-Won Shin, Dong-Yeul Kwon
Pages: 1335-1340
Published online on: 04 March 2014

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Article

Oxidized low-density lipoprotein increases the proliferation and migration of human coronary artery smooth muscle cells through the upregulation of osteopontin

Jun Liu, Yingang Ren, Li Kang, Lihua Zhang
Pages: 1341-1347
Published online on: 28 February 2014

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Article

Mangiferin increases Nrf2 protein stability by inhibiting its ubiquitination and degradation in human HL60 myeloid leukemia cells

Jie Zhao, Benping Zhang, Shanshan Li, Linglan Zeng, Yan Chen, Jun Fang
Pages: 1348-1354
Published online on: 12 March 2014

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Article

Identification of hypo- and hypermethylated genes related to atherosclerosis by a genome-wide analysis of DNA methylation

Yoshiji Yamada, Tamotsu Nishida, Hideki Horibe, Mitsutoshi Oguri, Kimihiko Kato, Motoji Sawabe
Pages: 1355-1340
Published online on: 10 March 2014

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Article

SOCS3 and SOCS6 are required for the risperidone-mediated inhibition of insulin and leptin signaling in neuroblastoma cells

Longzhen Piao, Jisoo Park, Yuwen Li, Sanghee Shin, Soyeon Shin, Gyeyeong Kong, Robin Shrestha, Quangdon Tran, Gang Min Hur, Jeong-Lan Kim, Jongsun Park
Pages: 1364-1370
Published online on: 10 March 2014

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Correction Open Access

[Erratum] Differential effect of statins on diabetic nephropathy in db/db mice

Yukinori Tamura, Toshinori Murayama, Manabu Minami, Masayuki Yokode, Hidenori Arai
Pages: 1371-1371
Published online on: 24 February 2014

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Journal Cover
August-2026 Volume 58 Issue 2

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Journal Metrics

Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Myokines in exercise‑mediated bone homeostasis: Molecular signaling mechanisms and therapeutic implications for bone disorders (Review)

Bin Tian, Xuesong Chen, Jiang Zheng, Xin Kang
Article Number: 231
Published online on: 24 June 2026

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Review Open Access

Neutrophil extracellular traps in thrombosis of hematologic malignancies: Underlying mechanisms and therapeutic opportunities (Review)

Kebing Lv, Zijie Ma, Qiuni Chen, Yang Su, Jingjing Ma, Chunling Wang, Liang Yu
Article Number: 230
Published online on: 23 June 2026

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Article Open Access

Recombinant myonectin ameliorates sepsis‑induced cardiomyopathy by alleviating mitochondrial dysfunction via the AdipoR1/AMPK pathway

Peipei Li, Rui Chen, Hanmo Zhang, Lihong Li, Huiling Luo, Beibei Du, Ping Yang
Article Number: 229
Published online on: 23 June 2026

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MTA2: Decoding pathogenic mechanisms, clinical implications and therapeutic frontiers across disease landscapes (Review)

Hao Xie, Ling Chen, Jing Gou, Xuehong Long, Ya Yang, Hai Hu, Ping Wu, Qibing Yan, Yongkang Wu
Article Number: 228
Published online on: 22 June 2026

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Mitochondria‑endoplasmic reticulum contact site nexus: Molecular integration, disease pathogenesis and therapeutic opportunities (Review)

Yi Liu, Xianda Che, Wei Wei, Chong Teng, Huimin Li
Article Number: 227
Published online on: 22 June 2026

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Metabolic messengers from the gut to the joint: Toward precision management of osteoarthritis (Review)

Ruipu Zhang, Liang Zhang, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 226
Published online on: 22 June 2026

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Retraction Open Access

[Retracted] Protection of telomeres 1 protein levels are associated with telomere length in gastric cancer

Kiyomu Fujii, Tomonori Sasahira, Yukiko Moriwaka, Naohide Oue, Wataru Yasui, Hiroki Kuniyasu
Article Number: 225
Published online on: 22 June 2026

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Article Open Access

Molecular mechanism of hydromorphone preconditioning in cerebral ischemia/reperfusion‑induced inflammatory injury

Jing Yao, Zeqing Huang, Songze Li, Minghui Lun, Jianing Fan
Article Number: 224
Published online on: 18 June 2026

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Article Open Access

Oridonin ameliorates ulcerative colitis by regulating the PI3K/AKT/mTOR signaling pathway to activate autophagy

Zhongxing Miao, Baohong Liu, Xingzhi Zhou, Mengru Lu, Ni Jia, Huamin Zhang, Ying Qi, Xiaoyu Tan, Qinggao Zhang
Article Number: 223
Published online on: 18 June 2026

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Article

Arsenic exposure and skin cancer: Mechanisms, clinical evidence and public health implications (Review)

Dimitrios A. Andreikos, Michael Aschner, Dimitrios C. Ziogas, Aristidis Tsatsakis, Demetrios A. Spandidos
Article Number: 222
Published online on: 18 June 2026

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Targeting glutathione metabolism for tumor radiosensitization (Review)

Haonan Xu, Meng Du, Xiaowen Liang, Xilin Xiao, Zhiyi Chen
Article Number: 221
Published online on: 16 June 2026

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Review Open Access

Effects of exercise‑derived extracellular vesicles: Epigenetic regulatory mechanisms and protective roles (Review)

Xinxin Zhang, Biao Zhang
Article Number: 220
Published online on: 15 June 2026

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Article Open Access

Moderate downregulation of NDUFA13 promotes cardiomyocytes proliferation and heart regeneration through the glycolysis/c‑Myc/Ccnd1 axis

Ying Gao, Ningjing Qian, Junyan Jin, Jiayi Liu, Bingqi Wang, Yaping Wang
Article Number: 219
Published online on: 12 June 2026

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Correction Open Access

[Corrigendum] (‑)‑Epigallocatechin‑3‑gallate attenuates myocardial injury induced by ischemia/reperfusion in diabetic rats and in H9c2 cells under hyperglycemic conditions

Yang Wu, Zhong-Yuan Xia, Bo Zhao, Yan Leng, Juan Dou, Qing-Tao Meng, Shao-Qing Lei, Zhi-Ze Chen, Jie Zhu
Article Number: 218
Published online on: 10 June 2026

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Article Open Access

Melatonin ameliorates circadian rhythm disruption induced erectile dysfunction by inhibiting oxidative stress mediated pyroptosis via Nrf2/HO‑1 axis

Qingtao Yang, Wei Li, Qi Yu, Jiang Shi, Lu Yang, Jun Qiao, Xi Wei, Changshi Gu, Fa Sun, Tao Li
Article Number: 217
Published online on: 09 June 2026

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Spatial architecture of immunometabolism: Mitochondrial‑organelle interfaces in immune signaling (Review)

Yaping Wu, Hao Yu, Ling Xia, Li Yang, Yu Zhou, Qian Yu
Article Number: 216
Published online on: 08 June 2026

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Urea cycle dysregulation and arginine pathways in the pathogenesis of NAFLD and NASH (Review)

Boying Zhu, Chaoyang Wang, Peng Liu, Zhifeng Qu, Ran Qi, Shengjiang Chen, Huanzhang Niu
Article Number: 215
Published online on: 08 June 2026

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Withaferin A, a candidate drug for lupus nephritis, confers renal protection via Pon1‑mediated attenuation of oxidative stress

Miao Xue, Junshuai Feng, Xiaorong Mao
Article Number: 214
Published online on: 08 June 2026

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Retraction Open Access

[Retracted] Classical dendritic cells regulate acute lung inflammation and injury in mice with lipopolysaccharide‑induced acute respiratory distress syndrome

Lang Li, Liang Dong, Dan Zhao, Fei Gao, Jie Yan
Article Number: 213
Published online on: 08 June 2026

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Review Open Access

Plant‑derived natural products alleviate dexamethasone‑induced skeletal muscle atrophy by modulating FoxO (Review)

Wei Dai, Jiabin Wu, Xiaotong Ma, Mingyu Wu, Ke Li, Haoyang Gao, Wenhong Wang, Weihua Xiao
Article Number: 212
Published online on: 05 June 2026

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Functional hydrogels in cardiovascular therapy: Design, applications and clinical challenges (Review)

Zheming Yang, Jiayin Li, Lingxiao Zhao, Dali Zhang, Chenghui Yan, Dan Liu, Yaling Han
Article Number: 211
Published online on: 04 June 2026

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Review Open Access

Experimental rodent models of cardiorenal syndrome types 3 and 4: Insights and clinical relevance (Review)

Stefanny M. Figueroa, Siyi Huang, Javier Reyes‑Osorio, Jean-Jacques Boffa, Cristián A. Amador, Christos E. Chadjichristos, Louis Boutin
Article Number: 210
Published online on: 04 June 2026

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Expression of Concern Open Access

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes

Zhanli Yang, Chuntao Yang, Liangcan Xiao, Xinxue Liao, Aiping Lan, Xiuyu Wang, Ruixian Guo, Peixi Chen, Chengheng Hu, Jianqiang Feng
Article Number: 209
Published online on: 03 June 2026

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Article Open Access

Microbiota‑derived indole‑3‑propionic acid reprograms bone marrow stem cell fate via PPARγ suppression to rescue osteoporosis

Jinwu Bai, Ruideng Wang, Jixing Fan, Shilong Su, Gao Si, Qinyong You, Ao Sun, Daole Hu, Shan Gao, Yang Lv, Fang Zhou
Article Number: 208
Published online on: 03 June 2026

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Article Open Access

Lactate regulates osteoclastogenesis via H3k18la in osteoarthritis

Zhibo Fan, Qiyue Fu, Tao Sun, Yutong Zhong, Yuefan Ma, Jingwei Jian, Shuosheng Yuan, Shenghong Li, Xiaomei Xu
Article Number: 207
Published online on: 02 June 2026

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Retraction Open Access

[Retracted] miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancert

Xiaoxu Gao, Yan Cai, Ruifang An
Article Number: 206
Published online on: 02 June 2026

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Review

Multi‑scale experimental models for the study of angiogenesis (Review)

Qin Yu, Jiarui Hu, Shuangshuang Yuan, Jiexia Gan, Mao Luo, Jianbo Wu, Liqun Wang
Article Number: 205
Published online on: 28 May 2026

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Review Open Access

Targeting lactylation in hepatocellular carcinoma: Mechanistic insights and therapeutic opportunities (Review)

Lianting Chen, Feiqiong Gao, Qianru Mei, Yujie Li, Qun Cai, Xudong Feng
Article Number: 204
Published online on: 28 May 2026

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Article Open Access

Oxygen‑sensing histone demethylase KDM6A modulates chondrocyte‑to‑osteoblast transdifferentiation by activating the Wnt/β‑catenin pathway

Yi Rong, Hao Yu, Heng Yin, Shaoshuo Li, Jianwei Wang, Zhongyuan Shen, Xinxin Ding, Fanchen Bu, Tianyi Dai, Gean Wu, Zhen Hua
Article Number: 203
Published online on: 28 May 2026

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September-2026 Volume 58 Issue 3

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Impact Factor: 8.5

CiteScore: 9.7

CiteScore Rank: Q1: #35/357 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Single‑cell atlas reveals a Wilms' tumor 1‑mediated axis driving granulosa cell senescence in human ovarian aging

Yanfang Du, Congyu Zhou, Yanpeng Tian, Zhongkang Li, Xianghua Huang
Article Number: 245
Published online on: 03 July 2026

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TRPV1‑mediated central sensitisation: Core mechanisms of migraine chronification and novel targeted therapeutic strategies (Review)

Mingxia Zhang, Yuting Pu, Yujie Zhang, Jia Hu, Shuangyang Li, Hongmei Tang, Bangjiang Fang, Xue Bai
Article Number: 244
Published online on: 02 July 2026

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Correction Open Access

[Corrigendum] Arginine ADP‑ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway

Lian Yang, Ming Xiao, Xian Li, Yi Tang, Ya-Lan Wang
Article Number: 243
Published online on: 02 July 2026

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Research progress on the chemical and pharmacological effects of Semen Strychni (Review)

Jingxin Mao, Xin Du, Dan Zeng, Xin Luo, Yan Li
Article Number: 242
Published online on: 02 July 2026

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Article Open Access

FLI1 enhances the malignant phenotype of glioma cells and exerts immunomodulatory effects through feedback crosstalk with exonic circRNA FECR1 and interferon‑induced ISG15

Xue Wen, Xiaoyi Gu, Xu Yan, Naifei Chen, Lei Zhou, Hui Li, Andrew R. Hoffman, Wei Li, Ji-Fan Hu, Jiuwei Cui
Article Number: 241
Published online on: 01 July 2026

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Review Open Access

Role of ZEB1 in angiogenesis and therapeutic potential (Review)

Ruoxin Ren, Chunxiao Yan, Yao Xiang, Lin Jin, Fang Cheng, Lijun Zhang
Article Number: 240
Published online on: 01 July 2026

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Endothelial dysfunction: A central mechanism linking autosomal dominant polycystic kidney disease and intracranial aneurysms (Review)

Xiaohong Xu, Ruyi Xu, Liexiang Zhang
Article Number: 239
Published online on: 01 July 2026

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Correction Open Access

[Corrigendum] Effect of SDF‑1/CXCR4 axis on the migration of transplanted bone mesenchymal stem cells mobilized by erythropoietin toward lesion sites following spinal cord injury

Jun Li, Weichun Guo, Min Xiong, Heng Han, Jie Chen, Dan Mao, Bing Tang, Hualong Yu, Yun Zeng
Article Number: 238
Published online on: 01 July 2026

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Exercise and fluoxetine in Alzheimer's disease: Molecular mechanisms of synergistic and antagonistic effects (Review)

Mei Wu, Yan Li
Article Number: 237
Published online on: 30 June 2026

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Oral‑gut axis in systemic disease: A barrier‑metabolism‑immunity three‑dimensional regulatory model (Review)

Qing Li, Mingrong Cheng, Weiwei Li, Xiaoyue Wang, Xiaoqing Liu, Yujie Yan
Article Number: 236
Published online on: 30 June 2026

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ABCG2 transporter: Structural and functional associations with gout (Review)

Muhammad Arslan Asif, Zeshan Zulfiqar, Bahar E. Mustafa, Usman Nazir, Jiamen Sun, Zhichang Wang, Yalei Cui, Sun Hao, Liu Boshuai, Yinghua Shi
Article Number: 235
Published online on: 30 June 2026

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Neuropilin‑1: Emerging roles in nerve‑vessel‑bone coupling during fracture repair (Review)

Keyue Zhang, Tong Li, Huan Liu, Huibo Ti, Zhenyu Zhang, Zhengdong Yuan, Junjie Wu, Xielin Yan, Zixin Luo, Haiting Hu, Xingchen Yao, Shuwen Shi, Xian Wu, Feng-Lai Yuan, Xiao Chen
Article Number: 234
Published online on: 30 June 2026

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Correction Open Access

[Corrigendum] Crocin exerts anti‑inflammatory and anti‑catabolic effects on rat intervertebral discs by suppressing the activation of JNK

Kang Li, Yan Li, Zhenjiang Ma, Jie Zhao
Article Number: 233
Published online on: 29 June 2026

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Skeletal muscle‑derived extracellular vesicles in multi‑organ degenerative disease: Mechanisms and therapeutic delivery perspectives (Review)

Xianji Wei, Chengyan Guo, Wei Zhang, Guanyi Wang, Wenjing Li, Binghong Gao, Bo Gao, Lingli Zhang
Article Number: 232
Published online on: 26 June 2026

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