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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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April-2015 Volume 11 Issue 4

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Cell-free fetal DNA and pregnancy-related complications (Review)

Stavros Sifakis, Zeta Koukou, Demetrios A. Spandidos
Pages: 2367-2372
Published online on: 19 December 2014

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Review

Targeting the proinflammatory cytokine tumor necrosis factor-α to alleviate cardiopulmonary bypass-induced lung injury (Review)

Mingxin Gao, Baodong Xie, Chengxiong Gu, Haitao Li, Fan Zhang, Yang Yu
Pages: 2373-2378
Published online on: 04 December 2014

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Article Open Access

Effect of OLIG1 on the development of oligodendrocytes and myelination in a neonatal rat PVL model induced by hypoxia-ischemia

Tongfei Cheng, Xindong Xue, Jianhua Fu
Pages: 2379-2386
Published online on: 01 December 2014

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Article Open Access

Therapeutic effect of human umbilical cord mesenchymal stem cells modified by angiotensin-converting enzyme 2 gene on bleomycin-induced lung fibrosis injury

Fang Min, Fengying Gao, Qian Li, Zhenwei Liu
Pages: 2387-2396
Published online on: 01 December 2014

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Article Open Access

Dynamic changes and functions of macrophages and M1/M2 subpopulations during ulcerative colitis-associated carcinogenesis in an AOM/DSS mouse model

Wei Wang, Xiayu Li, Danwei Zheng, Decai Zhang, Xiaoqing  Peng, Xuemei Zhang, Feiyan Ai, Xiaoyan Wang, Jian Ma, Wei Xiong, Guiyuan Li, Yanhong Zhou, Shourong Shen
Pages: 2397-2406
Published online on: 28 November 2014

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Article Open Access

Salinomycin inhibits the tumor growth of glioma stem cells by selectively suppressing glioma-initiating cells

Tunan Chen, Liang Yi, Fei Li, Rong Hu, Shengli Hu, Yi Yin, Chuan Lan, Zhao Li, Chuhua Fu, Liu Cao, Zhi Chen, Jishu Xian, Hua Feng
Pages: 2407-2412
Published online on: 01 December 2014

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Article Open Access

Ultrasound contrast-enhanced imaging and in vitro antitumor effect of paclitaxel-poly(lactic-co-glycolic acid)-monomethoxypoly (ethylene glycol) nanocapsules with ultrasound-targeted microbubble destruction

Jing Ma, Ling Xi Xing, Ming Shen, Fan Li, Ming Jie Zhu, Li Fang Jin, Zhaojun Li, Feng Gao, Yijin Su, You Rong Duan, Lian Fang Du
Pages: 2413-2420
Published online on: 10 December 2014

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Article Open Access

Histopathological assessment of inflammation and expression of inflammatory markers in patients with ketamine-induced cystitis

Hsin‑Chung Lin, Herng‑Sheng Lee, Tzong‑Shi Chiueh, Yu‑Chieh Lin, Hsin‑An Lin, Yu‑Chun Lin, Tai‑Lung Cha, En Meng
Pages: 2421-2428
Published online on: 18 December 2014

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Article Open Access

Resveratrol inhibits β-amyloid-induced neuronal apoptosis via regulation of p53 acetylation in PC12 cells

Zhibing Ai, Chengyan Li, Longti Li, Guohou He
Pages: 2429-2434
Published online on: 03 December 2014

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Article Open Access

Experimental research of host macrophage canceration induced by glioma stem progenitor cells

Aidong Wang, Xingliang Dai, Baoqian Cui, Xifeng Fei, Yanming Chen, Jinshi Zhang, Quanbin Zhang, Yaodong Zhao, Zhimin Wang, Hua Chen, Qing Lan, Jun Dong, Qiang Huang
Pages: 2435-2442
Published online on: 02 December 2014

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Article Open Access

Ubiquitously expressed transcript is a novel interacting protein of protein inhibitor of activated signal transducer and activator of transcription 2

Xiang Kong, Shikun Ma, Jiaqian Guo, Yan Ma, Yanqiu Hu, Jianjun Wang, Ying Zheng
Pages: 2443-2448
Published online on: 01 December 2014

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Article Open Access

Platelets are associated with xenograft tumor growth and the clinical malignancy of ovarian cancer through an angiogenesis-dependent mechanism

Lei Yuan, Xishi Liu
Pages: 2449-2458
Published online on: 11 December 2014

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Article Open Access

Resveratrol induces cell cycle arrest via a p53-independent pathway in A549 cells

Long Yuan, Yongrong Zhang, Juan Xia, Bin Liu, Qingyu Zhang, Jie Liu, Liming Luo, Zhou Peng, Zeqing Song, Runzhi Zhu
Pages: 2459-2464
Published online on: 16 December 2014

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Article Open Access

Volume-sensitive chloride channels are involved in cisplatin treatment of osteosarcoma

Siyi Cai, Tao Zhang, Dandan Zhang, Guixing Qiu, Yong Liu
Pages: 2465-2470
Published online on: 09 December 2014

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Article Open Access

Suppressive effects of induced pluripotent stem cell-conditioned medium on in vitro hypertrophic scarring fibroblast activation

Ye Ren, Chen‑Liang Deng, Wei‑Dong Wan, Jiang‑Hong  Zheng, Guang‑Yu  Mao, Song‑Lin  Yang
Pages: 2471-2476
Published online on: 18 December 2014

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Article Open Access

Changes in the expression of DNA-binding/differentiation protein inhibitors in neurons and glial cells of the gerbil hippocampus following transient global cerebral ischemia

Jae‑Chul Lee, Bai Hui Chen, Jeong‑Hwi Cho, In Hye Kim, Ji Hyeon Ahn, Joon Ha Park, Hyun‑Jin Tae, Geum‑Sil Cho, Bing Chun Yan, Dae Won Kim, In Koo Hwang, Jinseu Park, Yun Lyul Lee, Soo Young Choi, Moo‑Ho Won
Pages: 2477-2485
Published online on: 11 December 2014

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Article Open Access

Upregulation of D site of albumin promoter binding protein in the brain of patients with intractable epilepsy

Jinxian Yuan, Jing Guo, Melin Zhang, Qian Wang, Hao Huang, Yangmei Chen
Pages: 2486-2492
Published online on: 09 December 2014

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Article Open Access

Investigating the association between polymorphisms in connective tissue growth factor and susceptibility to colon carcinoma

Abrar Ahmad, Shlear Askari, Rahel Befekadu, Victoria Hahn-Strömberg
Pages: 2493-2503
Published online on: 11 December 2014

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Article Open Access

Effects of miR-19b knockdown on the cardiac differentiation of P19 mouse embryonic carcinoma cells Corrigendum in /mmr/12/6/8328

Xuehua Liu, Liming Yang, Huiyan Wang, Guofeng Xu, Shasha Zhu, Mengmeng Li, Xiaoshan Hu, Jingai Zhu, Chun Zhu, Jing Xu, Shuping Han, Zhangbin Yu
Pages: 2504-2512
Published online on: 03 December 2014

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Article Open Access

Cold ischemia-induced autophagy in rat lung tissue

Xu Chen, Jing‑Xiang Wu, Xing‑Ji You, Hong‑Wei Zhu, Jiong‑Lin Wei, Mei‑Ying Xu
Pages: 2513-2519
Published online on: 26 November 2014

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Article Open Access

Changes in integrin αv, vinculin and connexin43 in the medial prefrontal cortex in rats under single-prolonged stress

Yana Li, Fang Han, Yuxiu Shi
Pages: 2520-2526
Published online on: 02 December 2014

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Article Open Access

Analysis of the protein-protein interaction networks of differentially expressed genes in pulmonary embolism

Hao Wang, Chen Wang, Lei Zhang, Yinghua Lu, Qianglin Duan, Zhu Gong, Aibin Liang, Haoming Song, Lemin Wang
Pages: 2527-2533
Published online on: 26 November 2014

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Article Open Access

A novel long non-coding RNA, hypoxia-inducible factor-2α promoter upstream transcript, functions as an inhibitor of osteosarcoma stem cells in vitro

Yongcheng Wang, Jie Yao, Haoye Meng, Zhiguo Yu, Zhigang Wang, Xueling Yuan, Hong Chen, Aiyuan Wang
Pages: 2534-2540
Published online on: 01 December 2014

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Article Open Access

Identification of several hub-genes associated with periodontitis using integrated microarray analysis

Xinxing Guo, Yiling Wang, Chunling Wang, Jing Chen
Pages: 2541-2547
Published online on: 02 December 2014

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Article Open Access

Identification of differentially expressed genes regulated by transcription factors in glioblastomas by bioinformatics analysis

Bo Wei, Le Wang, Chao Du, Guozhang Hu, Lina Wang, Ying Jin, Daliang Kong
Pages: 2548-2554
Published online on: 15 December 2014

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Article Open Access

Lentivirus vector-mediated gene transduction of CNGRC peptide in rat adipose stem cells Corrigendum in /mmr/12/6/8329

Du Meng, Rui Liu, Li Pei, Lei Hou, Qian Ning, Qing Yu, Lu Feng, Xinhan Zhao
Pages: 2555-2561
Published online on: 03 December 2014

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Article Open Access

Synergistic antitumor effect of puerarin combined with 5-fluorouracil on gastric carcinoma

Xu‑Feng Guo, Zi‑Rong Yang, Jun Wang, Xiao‑Fei  Lei, Xiao‑Guang Lv, Wei‑Guo Dong
Pages: 2562-2568
Published online on: 27 November 2014

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Article Open Access

Astragalus and Paeoniae Radix Rubra extract (APE) inhibits hepatic stellate cell activation by modulating transforming growth factor-β/smad pathway

Weijuan Huang, Lin Li, Xiaopeng Tian, Jinjin Yan, Xinzheng Yang, Xinlong Wang, Guozhen Liao, Genquan Qiu
Pages: 2569-2577
Published online on: 01 December 2014

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Article Open Access

RNA interference-mediated silencing of G protein-coupled receptor 137 inhibits human gastric cancer cell growth

Zishu Wang, Hui Zhang, Junbin Wang, Yan Yang, Qiong Wu
Pages: 2578-2584
Published online on: 15 December 2014

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Article Open Access

Fourier transform infrared microspectroscopy monitoring of 5-fluorouracil-induced apoptosis in SW620 colon cancer cells

Yanfeng Gao, Xiongwei Huo, Liu Dong, Xuejun Sun, He Sai, Guangbing Wei, Yizhuang Xu, Yuanfu Zhang, Jinguang Wu
Pages: 2585-2591
Published online on: 12 December 2014

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Article Open Access

Molecular responses of radiation-induced liver damage in rats

Wei   Cheng, Lei Xiao, Aimudula Ainiwaer, Yunlian Wang, Ge Wu, Rui Mao, Ying Yang, Yongxing Bao
Pages: 2592-2600
Published online on: 04 December 2014

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Article Open Access

Pioglitazone inhibits high glucose-induced expression of receptor for advanced glycation end products in coronary artery smooth muscle cells

Bei‑Bing Di, Hong‑Wei Li, Wei‑Ping Li, Xu‑Hua Shen, Zhi‑Jun Sun, Xing Wu
Pages: 2601-2607
Published online on: 18 December 2014

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Article Open Access

Adventitial gene transfer of catalase attenuates angiotensin II-induced vascular remodeling

Cun‑Fei Liu, Jia Zhang, Kai Shen, Ping‑Jin Gao, Hai‑Ya Wang, Xin Jin, Chao Meng, Ning‑Yuan Fang
Pages: 2608-2614
Published online on: 10 December 2014

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Article Open Access

Role of inflammation in the initiation and maintenance of atrial fibrillation and the protective effect of atorvastatin in a goat model of aseptic pericarditis

Ye Zhang, Yu‑Tang Wang, Zhao‑Liang Shan, Hong‑Yang  Guo, Yuan Guan, Hong‑Tao Yuan
Pages: 2615-2623
Published online on: 18 December 2014

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Article Open Access

Identification of histamine receptor subtypes in skeletal myogenesis

Yan Chen, Vasily Stegaev, Vesa‑Petteri Kouri, Tarvo Sillat, Paul  L. Chazot, Holger Stark, Jian Guo Wen, Yrjö T. Konttinen
Pages: 2624-2630
Published online on: 10 December 2014

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Article Open Access

Aberrant expression of long noncoding RNAs in chronic thromboembolic pulmonary hypertension

Song Gu, Guanghui Li, Xitao Zhang, Jun Yan, Jie Gao, Xiangguang An, Yan Liu, Pixiong Su
Pages: 2631-2643
Published online on: 17 December 2014

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Article Open Access

Serum Golgi protein 73 levels and liver pathological grading in cases of chronic hepatitis B

Zhengju Xu, Xingnan Pan, Kaipeng Wei, Hongbing Ding, Meijuan Wei, Huanwen Yang, Qian Liu
Pages: 2644-2652
Published online on: 18 December 2014

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Article

Angiopoietin-like protein 2 is a potential biomarker for gastric cancer

Takuma Yoshinaga, Takamasa Shigemitsu, Hiroto Nishimata, Takayuki Takei, Masahiro Yoshida
Pages: 2653-2658
Published online on: 03 December 2014

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Article

Reduction of fibroproliferative changes in irradiated rat lung with soluble transforming growth factor-β receptor

Akihito Nishioka, Yasuhiro Ogawa, Shinji Kariya, Norihiko Hamada, Munenobu Nogami, Taisuke Inomata, Hikaru Ueno
Pages: 2659-2663
Published online on: 09 December 2014

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Article

Reduction of connexin 37 expression by RNA interference decreases atherosclerotic plaque formation

Suxia Guo, Jihong Zhu, Zhenyu Yang, Jian Feng, Kulin Li, Ruxing Wang, Xiangjun Yang
Pages: 2664-2670
Published online on: 04 December 2014

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Article

Positive nin one binding protein expression predicts poor outcome in prostate cancer

Jie Chen, Junkai Wang, Xingang Cui, Yushan Liu, Lei  Yin, Yao Li, Lu Chen, Danfeng Xu, Yi Gao
Pages: 2671-2676
Published online on: 09 December 2014

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Article

Hypoxia induces autophagy in human vascular endothelial cells in a hypoxia-inducible factor 1‑dependent manner

Jianbo Wu, Zhen Lei, Jingui Yu
Pages: 2677-2682
Published online on: 15 December 2014

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Article

Protein kinase C signaling pathway involvement in cardioprotection during isoflurane pretreatment

Hongbo Li, Xiao‑E Lang
Pages: 2683-2688
Published online on: 03 December 2014

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Article

Piperlongumine attenuates collagen-induced arthritis via expansion of myeloid-derived suppressor cells and inhibition of the activation of fibroblast-like synoviocytes

Jian Sun, Ping Xu, Xueping Du, Qinggang Zhang, Yuchang Zhu
Pages: 2689-2694
Published online on: 26 November 2014

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Article

Increased expression of endocan in arthritic synovial tissues: Effects of adiponectin on the expression of endocan in fibroblast-like synoviocytes

Kyoung Soo Kim, Yeon-Ah Lee, Hye-In Ji, Ran Song, Jung Yeon Kim, Sang‑Hoon Lee, Seung-Jae Hong, Myung Chul Yoo, Hyung-In Yang
Pages: 2695-2702
Published online on: 05 December 2014

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Article

β-catenin induces A549 alveolar epithelial cell mesenchymal transition during pulmonary fibrosis

Ping Song, Jin‑Xu Zheng, Jiao Xu, Ji‑Zhu Liu, Li‑Yan Wu, Chao Liu
Pages: 2703-2710
Published online on: 27 November 2014

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Article

Glucocorticoids induce autophagy in rat bone marrow mesenchymal stem cells

Long Wang, Jing Fan, Yan‑Shui Lin, Yun‑Shan Guo, Bo Gao, Qi‑Yue  Shi, Bo‑Yuan Wei, Li Chen, Liu Yang, Jian Liu, Zhuo‑Jing Luo
Pages: 2711-2716
Published online on: 16 December 2014

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Article

Smad4 suppresses the progression of renal cell carcinoma via the activation of forkhead box protein H1

Yunli Liu, Yangyang Xu, Xuedong Li, Zhaoyan Chen
Pages: 2717-2722
Published online on: 08 December 2014

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Article

Cyanidin-3‑glucoside isolated from mulberry fruits protects pancreatic β-cells against glucotoxicity-induced apoptosis

Jong Seok Lee, Young Rae Kim, Jun Myoung Park, Young Eon Kim, Nam In Baek, Eock Kee Hong
Pages: 2723-2728
Published online on: 11 December 2014

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Article

A family with axonal sensorimotor polyneuropathy with TUBB3 mutation

Young Bin Hong, Ja Hyun Lee, Hyung Jun Park, Yu‑Ri Choi, Young Se Hyun, Ji Hoon Park, Heasoo Koo, Ki Wha Chung, Byung‑Ok Choi
Pages: 2729-2734
Published online on: 04 December 2014

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Article

Impact of the alterations in the interstitial cells of Cajal on intestinal motility in post-infection irritable bowel syndrome

Bo Yang, Xu‑Chun Zhou, Cheng Lan
Pages: 2735-2740
Published online on: 03 December 2014

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Article

Modulation of nuclear factor-κB-mediated pro-inflammatory response is associated with exogenous administration of bone marrow-derived mesenchymal stem cells for treatment of experimental colitis

Dongmei Zuo, Qing Tang, Heng Fan, Zhexing Shou, Xingxing Liu, Dan Cao, Zhou Zou
Pages: 2741-2748
Published online on: 03 December 2014

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Article

Deoxycholic acid inhibits the growth of BGC-823 gastric carcinoma cells via a p53‑mediated pathway

Hai‑Bo Yang, Wei Song, Mei‑Die Cheng, Hai‑Fang Fan, Xu Gu, Ying Qiao, Xin Lu, Rui‑He Yu, Lan‑Ying Chen
Pages: 2749-2754
Published online on: 26 November 2014

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Article

Allicin induces apoptosis of the MGC-803 human gastric carcinoma cell line through the p38 mitogen-activated protein kinase/caspase-3 signaling pathway

Xuecheng Zhang, Yong Zhu, Wei Duan, Chen Feng, Xuan He
Pages: 2755-2760
Published online on: 18 December 2014

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Article

Tumor necrosis factor receptor-associated factor 6 promotes migration of rheumatoid arthritis fibroblast-like synoviocytes

Huiqin Wang, Weixia Chen, Ling Wang, Faxin Li, Chunling Zhang, Li Xu
Pages: 2761-2766
Published online on: 17 December 2014

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Article

Establishment and biological characteristics of acquired gefitinib resistance in cell line NCI-H1975/gefinitib-resistant with epidermal growth factor receptor T790M mutation

Bao‑Xia Zhao, Jing Wang, Bo Song, Hong Wei, Wei‑Peng Lv, Li‑Min Tian, Mei Li, Shen Lv
Pages: 2767-2774
Published online on: 08 December 2014

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Article

Zipper-interacting protein kinase interacts with human cell division cycle 14A phosphatase

Wei Wu, Haiying Hu, Zi Ye, Mancheong Leong, Min  He, Qin Li, Renming Hu, Shuo Zhang
Pages: 2775-2780
Published online on: 09 December 2014

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Article

Identification of oxidative stress-induced gene expression profiles in cavernosal endothelial cells

Chao Hu, Yin‑Ying Dong, Ye‑Hao Dong, Jie‑Feng Cui, Ji‑Can Dai
Pages: 2781-2788
Published online on: 18 December 2014

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Article

Co-expression of immunoglobulin-like transcript 4 and angiopoietin-like proteins in human non-small cell lung cancer

Linlin Wang, Ting Geng, Xiaosun Guo, Jie Liu, Pei Zhang, Dong Yang, Juan Li, Shuwen Yu, Yuping Sun
Pages: 2789-2796
Published online on: 02 December 2014

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Article

Expression of hepatocyte growth factor and c-Met in non-small-cell lung cancer and association with lymphangiogenesis

Nan Zhang, Fubo Xie, Wei Gao, Shuwen Yu, Liyun Qiu, Wenli Lin, Yuping Sun, Tanghong Jia
Pages: 2797-2804
Published online on: 10 December 2014

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Article

MicroRNA‑133b inhibits connective tissue growth factor in colorectal cancer and correlates with the clinical stage of the disease

Yihang Guo, Xiaorong Li, Changwei Lin, Yi Zhang, Gui Hu, Jianyu Zhou, Juan Du, Kai Gao, Yi Gan, Hao Deng
Pages: 2805-2812
Published online on: 10 December 2014

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Article

Caspase-3‑resistant uncleavable form of acidic leucine-rich nuclear phosphoprotein 32B potentiates leukemic cell apoptosis

Cai‑Xia Li, Shao‑Ming Shen, Li‑Shun Wang, Yun Yu
Pages: 2813-2818
Published online on: 03 December 2014

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Article

A hemagglutinin quantification method for development of an influenza pandemic vaccine using size exclusion high performance liquid chromatography

Hang Sik Roh, Hye Min Song, Bo Reum Yun, Hyun Kyung Kang, Keum Suk Choi, Yun Ju Park, Dong Sub Kim, Seung Hee Kim, In Pil Mo, Beum‑Soo An, Chi Young Ahn
Pages: 2819-2824
Published online on: 04 December 2014

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Article

Antisense oligonucleotides targeting human telomerase mRNA increases the radiosensitivity of nasopharyngeal carcinoma cells

Change Yu, Ying Yu, Zumin Xu, Haiwen Li, Dongyan Yang, Mei Xiang, Yufang Zuo, Shuhui Li, Zihong Chen, Zhonghua Yu
Pages: 2825-2830
Published online on: 17 December 2014

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Article

Paracrine factors from mesenchymal stem cells attenuate epithelial injury and lung fibrosis

Qinqin Shen, Bing Chen, Zhifeng Xiao, Lifen Zhao, Xuefeng Xu, Xuan Wan, Mulan Jin, Jianwu Dai, Huaping Dai
Pages: 2831-2837
Published online on: 15 December 2014

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Article

miR-203 sensitizes glioma cells to temozolomide and inhibits glioma cell invasion by targeting E2F3

Guodong Tang, Jun Wu, Gelei Xiao, Lei Huo
Pages: 2838-2844
Published online on: 16 December 2014

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Article

Gypenosides attenuate cholesterol‑induced DNA damage by inhibiting the production of reactive oxygen species in human umbilical vein endothelial cells

Yuan Quan, Yijun Yang, Huixing Wang, Bo Shu, Qi‑Hai Gong, Minzhang Qian
Pages: 2845-2851
Published online on: 16 December 2014

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Antibacterial activity and mode of action of the Artemisia capillaris essential oil and its constituents against respiratory tract infection-causing pathogens

Chang Yang, Dong-Hui Hu, Yan Feng
Pages: 2852-2860
Published online on: 17 December 2014

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Article

Poly(ADP) ribose polymerase-1 ablation alters eicosanoid and docosanoid signaling and metabolism in a murine model of contact hypersensitivity

Borbála Kiss, Magdolna Szántó, Mónika Szklenár, Attila Brunyánszki, Tamás Marosvölgyi, Eszter Sárosi, Éva Remenyik, Pál Gergely, László Virág, Tamás Decsi, Ralph Rühl, Peter Bai
Pages: 2861-2867
Published online on: 04 December 2014

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Article

Overexpression of CYP3A5 attenuates inducibility and activity of CYP3A4 in HepG2 cells

Zemin Kuang, Zhijun Huang, Ying Li, Guoping Yang, Meilin Liu, Hong Yuan
Pages: 2868-2874
Published online on: 01 December 2014

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Article

Expression of β-nerve growth factor and homeobox A10 in experimental cryptorchidism treated with exogenous nerve growth factor

Hua Xian, Yun Xian, Lili Liu, Yongjun Wang, Jianghong He, Jianfei Huang
Pages: 2875-2881
Published online on: 26 November 2014

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Article

Aquaporin 3 promotes prostate cancer cell motility and invasion via extracellular signal-regulated kinase 1/2-mediated matrix metalloproteinase-3 secretion

Jie Chen, Zhijun Wang, Danfeng Xu, Yushan Liu, Yi Gao
Pages: 2882-2888
Published online on: 16 December 2014

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Article

MicroRNA-146a and -21 cooperate to regulate vascular smooth muscle cell proliferation via modulation of the Notch signaling pathway

Jian Cao, Kui Zhang, Jubing Zheng, Ran Dong
Pages: 2889-2895
Published online on: 17 December 2014

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Article

Effect of charred Radix et Rhizoma Rhei in a laser-induced choroidal neovascularization murine model

Dongmei Han, Yuan Yao, Yong Sun, Yuanyuan Gong, Xingwei Wu
Pages: 2896-2902
Published online on: 04 December 2014

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Article

Differential microRNA expression profiles in HCT116 colorectal cancer cell lines located in the lung and colon

Xiao‑Hong Wang, Xin‑Min Yu, Hong Jiang, Cong Luo
Pages: 2903-2907
Published online on: 27 November 2014

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Article

Histone deacetylase inhibitor suberoyl bis-hydroxamic acid suppresses cell proliferation and induces apoptosis in breast cancer cells

Xinmiao Yang, Ning Zhang, Zeliang Shi, Zhangyu Yang, Xichun Hu
Pages: 2908-2912
Published online on: 11 December 2014

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Article

Protein extracts of Crassostrea gigas alleviate CCl4-induced hepatic fibrosis in rats by reducing the expression of CTGF, TGF-β1 and NF-κB in liver tissues

Jue Zhou, Yi Liang, Jie‑Xue Pan, Fang‑Fang Wang, Xian‑Ming  Lin, Rui‑Jie Ma, Fan Qu, Jian‑Qiao Fang
Pages: 2913-2920
Published online on: 28 November 2014

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Article

Mycobacterium tuberculosis 19-kDa lipoprotein induces Toll-like receptor 2-dependent peroxisome proliferator-activated receptor γ expression and promotes inflammatory responses in human macrophages

Li Liu, Jincheng Liu, Guoqiang Niu, Qianhong Xu, Qiliang Chen
Pages: 2921-2926
Published online on: 10 December 2014

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Article

WSKY, a traditional Chinese decoction, rescues cognitive impairment associated with NMDA receptor antagonism by enhancing BDNF/ERK/CREB signaling

Xin Guo, Zheng‑Hua Chen, Hui‑Ling Wang, Zhong‑Chun Liu, Xiao‑Ping Wang, Ben‑Hong Zhou, Can Yang, Xue‑Ping Zhang, Ling Xiao, Chang Shu, Jian‑Xin Chen, Gao‑Hua Wang
Pages: 2927-2934
Published online on: 12 December 2014

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Article

Combination of Taxol® and dichloroacetate results in synergistically inhibitory effects on Taxol-resistant oral cancer cells under hypoxia

Qi  Xie, Han‑Fang  Zhang, Ying‑Zi  Guo, Peng‑Yi  Wang, Zhong‑Shung  Liu, Hua‑Dong  Gao, Wei‑Li  Xie
Pages: 2935-2940
Published online on: 11 December 2014

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Article

Inositol-requiring enzyme 1-mediated endoplasmic reticulum stress triggers apoptosis and fibrosis formation in liver cirrhosis rat models

Tianpeng Jiang, Lizhou Wang, Xing Li, Jie Song, Xiaoping Wu, Shi Zhou
Pages: 2941-2946
Published online on: 28 November 2014

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Article

MicroRNA-100 functions as a tumor suppressor by inhibiting Lgr5 expression in colon cancer cells

Ming-Kai Zhou, Xiao-Jun Liu, Zhi-Guo Zhao, Yi-Meng Cheng
Pages: 2947-2952
Published online on: 04 December 2014

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Article

Effects of tachyplesin I on human U251 glioma stem cells

Hong Ding, Gang Jin, Lijun Zhang, Jianguo Dai, Jianzhang Dang, Yali Han
Pages: 2953-2958
Published online on: 28 November 2014

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Article

Ganglioside GM3 exerts opposite effects on motility via epidermal growth factor receptor and hepatocyte growth factor receptor-mediated migration signaling

Ying Li, Xiaohua Huang, Congcong Wang, Yuzhong Li, Mingchun Luan, Keli Ma
Pages: 2959-2966
Published online on: 12 December 2014

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Article

Identification of suitable reference genes for investigating gene expression in human gallbladder carcinoma using reverse transcription quantitative polymerase chain reaction

Shan Yu, Qiwei Yang, Jing Hui Yang, Zhenwu Du, Guizhen Zhang
Pages: 2967-2974
Published online on: 27 November 2014

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Article

Investigating the potential genetic association between RANBP9 polymorphisms and the risk of schizophrenia

Joon Seol Bae, Jason Yongha Kim, Byung‑Lae Park, Hyun Sub Cheong, Jeong‑Hyun Kim, Suhg Namgoong, Ji‑On Kim, Chul Soo Park, Bong‑Jo Kim, Cheol‑Soon Lee, Migyung Lee, Woo Hyuk Choi, Tae‑Min Shin, Jaeuk Hwang, Hyoung Doo Shin, Sung‑Il Woo
Pages: 2975-2980
Published online on: 04 December 2014

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Article

Overexpression of astrocyte-elevated gene-1 is associated with ovarian cancer development and progression

Bo Zhou, Jue Yang, Bin Shu, Kunmei Liu, Lezhen Xue, Ning Su, Jing Liu, Tao Xi
Pages: 2981-2990
Published online on: 05 December 2014

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Article

Characterization, antioxidant and cytotoxic activity of sulfated derivatives of a water-insoluble polysaccharides from Dictyophora indusiata

Chao Deng, Jingjing Xu, Haitian Fu, Jinghua Chen, Xin Xu
Pages: 2991-2998
Published online on: 08 December 2014

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Article

Multi-dose parecoxib provides an immunoprotective effect by balancing T helper 1 (Th1), Th2, Th17 and regulatory T cytokines following laparoscopy in patients with cervical cancer

Wenguang Ma, Kun Wang, Jongqiang Du, Junqi Luan, Ge Lou
Pages: 2999-3008
Published online on: 26 November 2014

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Article

Effects of focal mild hypothermia on thrombin-induced brain edema formation and the expression of protease activated receptor-1, matrix metalloproteinase-9 and aquaporin 4 in rats

Dapeng Gao, Feifan Ding, Gongwen Lei, Guohui Luan, Shibao  Zhang, Kesen Li, Desheng Wang, Liming Zhang, Dawei Dai
Pages: 3009-3014
Published online on: 18 December 2014

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Article

Changes in von Willebrand factor and ADAMTS-13 in patients following arthroplasty

Ling Liu, Jing Ling, Zhenni Ma, Quan Yuan, Jun Pan, Huilin Yang
Pages: 3015-3020
Published online on: 03 December 2014

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Article

Celecoxib derivative OSU-03012 inhibits the proliferation and activation of hepatic stellate cells by inducing cell senescence

Jun Zhang, Miao Wang, Zuowei Zhang, Zhongguang Luo, Fei Liu, Jie Liu
Pages: 3021-3026
Published online on: 04 December 2014

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Article

Pituitary gene expression differs in D-galactose-induced cell senescence and steroid-induced prolactinomas

Tiehui Zhang, Binhai Zhao, Jia Li, Chunlei Zhang, Hongzhi  Li, Jiang Wu, Shiming Zhang, Guozhen Hui
Pages: 3027-3032
Published online on: 08 December 2014

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Article

Silencing of polo-like kinase 2 increases cell proliferation and decreases apoptosis in SGC-7901 gastric cancer cells

Li Ying Liu, Wei Wang, Ling Yu Zhao, Bo Guo, Juan Yang, Xiao Ge Zhao, Tu Sheng Song, Chen Huang, Ji Ru Xu
Pages: 3033-3038
Published online on: 11 December 2014

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Article

CpG island promoter hypermethylation of Ras association domain family 1A gene contributes to gastric carcinogenesis

Moon Kyung Joo, Key Hyeon Kim, Jong‑Jae Park, Hyo Soon Yoo, Jungwan Choe, Hyo Jung Kim, Beom Jae Lee, Jae Seon Kim, Young‑Tae Bak
Pages: 3039-3046
Published online on: 05 December 2014

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Article

Identification of differentially expressed genes and small molecule drugs for the treatment of tendinopathy using microarray analysis

Xinyu Cai, Ming Cai, Lieming Lou
Pages: 3047-3054
Published online on: 11 December 2014

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Article

Gene co-expression network and function modules in three types of glioma

Gang Li, Weiran Pan, Xiaoxiao Yang, Jinming Miao
Pages: 3055-3063
Published online on: 27 November 2014

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FOXO1-mediated epigenetic modifications are involved in the insulin-mediated repression of hepatocyte aquaporin 9 expression

Lie‑Wang Qiu, Lu‑Yun Gu, Lin Lü, Xiao‑Feng Chen, Chuan‑Fei Li, Zhe‑Chuan Mei
Pages: 3064-3068
Published online on: 12 December 2014

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Article

DHA-1 plasmid-mediated AmpC β-lactamase expression and regulation of Klebsiella pnuemoniae isolates

Ying Luan, Gui-Ling Li, Li-Bo Duo, Wei-Ping Wang, Cheng-Ying Wang, He-Guang Zhang, Fei He, Xin He, Shu-Juan Chen, Dan-Ting Luo
Pages: 3069-3077
Published online on: 05 December 2014

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Article

Efficient delivery of docetaxel for the treatment of brain tumors by cyclic RGD-tagged polymeric micelles

Ai‑Jun Li, Yue‑Hua Zheng, Guo‑Dong Liu, Wei‑Sheng Liu, Pei‑Cheng Cao, Zhen‑Fu Bu
Pages: 3078-3086
Published online on: 28 November 2014

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Article

Curcumin and its major metabolites inhibit the inflammatory response induced by lipopolysaccharide: Translocation of nuclear factor-κB as potential target

Feng Zhao, Yudian Gong, Yuan Hu, Minghui Lu, Jing Wang, Jianxin Dong, Daquan Chen, Lei Chen, Fenghua Fu, Feng Qiu
Pages: 3087-3093
Published online on: 11 December 2014

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Article

Anticancer agent icaritin induces apoptosis through caspase-dependent pathways in human hepatocellular carcinoma cells

Li Sun, Qisong Peng, Lili Qu, Lailing Gong, Jin Si
Pages: 3094-3100
Published online on: 26 November 2014

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Article

p38MAPK activation mediates tumor necrosis factor-α‑induced apoptosis in glioma cells

Bicheng Zhang, Tingting Wu, Zhigang Wang, Yafei Zhang, Jun  Wang, Bo  Yang, Yong  Zhao, Zhiguo  Rao, Jianfei  Gao
Pages: 3101-3107
Published online on: 26 November 2014

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Article

MicroRNA-145 inhibits lung cancer cell metastasis

Dong‑Jin Ling, Zhong‑Shu Chen, Yang‑De Zhang, Qian‑De  Liao, Jian‑Xiong Feng, Xue‑Yu  Zhang, Tian‑Sheng Shi
Pages: 3108-3114
Published online on: 03 December 2014

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Article

Janus kinase/signal transducer and activator of transcription inhibitors enhance the protective effect mediated by tanshinone IIA from hypoxic/ischemic injury in cardiac myocytes

Mei‑Qi Zhang, Jian‑Feng Tu, Huan Chen, Ye Shen, Ling‑Xiao Pang, Xiang‑Hong Yang, Ren‑Hua Sun, Yue‑Liang Zheng
Pages: 3115-3121
Published online on: 09 December 2014

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Article

Akt regulates β-catenin in a rat model of focal cerebral ischemia-reperfusion injury

Xue‑Song Xing, Fang Liu, Zhi‑Yi He
Pages: 3122-3128
Published online on: 26 November 2014

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Article

Cadmium depletes cellular iron availability through enhancing ferroportin translation via iron responsive element

Li Sun, Lixin Wang, Zhe Wang, Wei He, Shuping Zhang, Wenli Guo, Yi Qian, Hong Ji, Haiqin Rong, Sijin Liu
Pages: 3129-3133
Published online on: 27 November 2014

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Article

Effective expansion of forkhead box P3+ regulatory T cells via early secreted antigenic target 6 and antigen 85 complex B from Mycobacterium tuberculosis

Ying‑E Wu, Zhong‑Ren Du, Ying‑Mu Cai, Wen‑Guang Peng, Gao‑Zhe Zheng, Geng‑Long Zheng, Li‑Biao Wu, Ke Li
Pages: 3134-3142
Published online on: 03 December 2014

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Article

Inhibitory effects of imatinib on vitamin D3 synthesis in human keratinocytes

Lysann Michaela Mehlig, Claudia Garve, Josephine Tabea Tauer, Meinolf Suttorp, Andrea Bauer
Pages: 3143-3147
Published online on: 10 December 2014

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Article

Iodine-131 induces apoptosis in HTori-3 human thyrocyte cell line and G2/M phase arrest in a p53-independent pathway

Weixiao Zhang, Rui Gao, Yan Yu, Kun Guo, Peng  Hou, Mingqi Yu, Yan Liu, Aimin Yang
Pages: 3148-3154
Published online on: 16 December 2014

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Article

Forkhead box C1 promoter upstream transcript, a novel long non-coding RNA, regulates proliferation and migration in basal-like breast cancer

Juntao Liu, Lei Shen, Jie Yao, Yi Li, Yongcheng Wang, Hong Chen, Peiliang Geng
Pages: 3155-3159
Published online on: 15 December 2014

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Article

Sann-Joong-Kuey-Jian-Tang decreases the protein expression of mammalian target of rapamycin but increases microtubule associated protein II light chain 3 expression to inhibit human BxPC‑3 pancreatic carcinoma cells

Chin‑Cheng Su
Pages: 3160-3166
Published online on: 15 December 2014

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Article

Ginsenoside Rg1 attenuates invasion and migration by inhibiting transforming growth factor-β1-induced epithelial to mesenchymal transition in HepG2 cells

Meiling Yu, Xiaobing Yu, Daohua Guo, Binbin Yu, Li Li, Qiao Liao, Rong Xing
Pages: 3167-3173
Published online on: 16 December 2014

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Article

Comparative analysis of cytotoxic T lymphocyte response induced by dendritic cells pulsed with recombinant adeno-associated virus carrying α-fetoprotein gene or cancer cell lysate

Jun Zhou, Ping Ma, Jun Li, Wei Song
Pages: 3174-3180
Published online on: 08 December 2014

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Article

Regulatory T cells protect against hypoxia-induced pulmonary arterial hypertension in mice

Yanbiao Chu, Xiaoying Xiangli, Wei Xiao
Pages: 3181-3187
Published online on: 17 December 2014

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Article

RPL13A as a reference gene for normalizing mRNA transcription of ovarian cancer cells with paclitaxel and 10-hydroxycamptothecin treatments

Zehua Bian, Yang Yu, Chao Quan, Rongwei Guan, Yan Jin, Jie  Wu, Lidan Xu, Feng Chen, Jing Bai, Wenjing Sun, Songbin Fu
Pages: 3188-3194
Published online on: 17 December 2014

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Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
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NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
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Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
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TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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Retraction Open Access

[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
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Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Review Open Access

Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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Retraction Open Access

[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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Article Open Access

MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Review Open Access

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Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
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Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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Review Open Access

From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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Correction Open Access

[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Review Open Access

Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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Review

RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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