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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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March 2012 Volume 5 Issue 3

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article

Overexpression of GLUT1 correlates with Kras mutations in lung carcinomas

Hidefumi Sasaki, Masayuki Shitara, Keisuke Yokota, Yu Hikosaka, Satoru Moriyama, Motoki Yano, Yoshitaka Fujii
Pages: 599-602
Published online on: 22 December 2011

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Article

Differential effects of calcium antagonists on ABCG2/BCRP-mediated drug resistance and transport in SN-38-resistant HeLa cells

Kohji Takara, Mika Matsubara, Kazuhiro Yamamoto, Tetsuya Minegaki, Shigehiko Takegami, Minoru Takahashi, Teruyoshi Yokoyama, Katsuhiko Okumura
Pages: 603-609
Published online on: 22 December 2011

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Article

Marine fungal metabolite 1386A alters the microRNA profile in MCF-7 breast cancer cells

Bing Tang, Wei-Ling He, Cheng Zheng, Tuck-Yun Cheang, Xi-Fang Zhang, Hui Wu, Hui-Ling Yang
Pages: 610-618
Published online on: 07 December 2011

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Article

Nogo-66 receptor activation inhibits neurite outgrowth and increases β-amyloid protein secretion of cortical neurons

Fei Xiao, Lian-Feng Lin, Xin Cheng, Qin Gao, Huan-Min Luo
Pages: 619-624
Published online on: 01 December 2011

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Article

bFGF peptide combined with the pVAX-8CpG plasmid as adjuvant is a novel anticancer vaccine inducing effective immune responses against Lewis lung carcinoma

Meng Li, Hua Shan Shi, Hai Long Zhang, Zi Chao Luo, Yang Wan, Lian Lu, Shun-Tao Luo, Li Yang
Pages: 625-630
Published online on: 20 December 2011

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Article

In vivo treatment of HCV core-positive HepG2 cells with the transfer of recombinant caspase-3 using a 2'-5' OAS promoter

Yuan Zi, Ying Wang, Peter S. Wiegmann, Junming Luo, Deyun Feng
Pages: 631-636
Published online on: 09 December 2011

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Article

Chemopreventive effect of saikosaponin-d on diethylinitrosamine-induced hepatocarcinogenesis: Involvement of CCAAT/enhancer binding protein β and cyclooxygenase-2

Xin-Lan Lu, Shui-Xiang He, Mu-Dan Ren, Yan-Li Wang, Ya-Xin Zhang, En-Qi Liu
Pages: 637-644
Published online on: 09 December 2011

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Article

Tetramethylpyrazine attenuates PPAR-γ antagonist-deteriorated oxazolone-induced colitis in mice

Xiangyi He, Zhong Zheng, Xiangyi Yang, Yunmin Lu, Niwei Chen, Weixiong Chen
Pages: 645-650
Published online on: 19 December 2011

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Article

Endothelin-1 and type III collagen alterations in the heart of rats following cisplatin-induced toxicity

Quan-Yong Huang, Xue-Fang Li, Shui-Ping Liu
Pages: 651-654
Published online on: 13 December 2011

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Article

Synergistic effects of telmisartan and pyridoxamine on early renal damage in spontaneously hypertensive rats

Pengli Zhu, Hong Lin, Chengai Sun, Fan Lin, Huizhen Yu, Xiuping Zhuo, Chanjuan Zhou, Zhisheng Deng
Pages: 655-662
Published online on: 19 December 2011

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Article

Increased sTREM-1 in pregnant women with premature rupture of membranes and subclinical chorioamnionitis

Jianping Wang, Yiji Zhang, hanqing Zhang, Wanglei  Qu, Jieqiang Lv, Yuhuan Wang, Jian Xiao
Pages: 663-667
Published online on: 13 December 2011

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Article

Apoptotic effect of Vibrio vulnificus cytolysin on A549 human lung adenocarcinoma cells

Jiachun Sun, Jing Zheng, Guiming Wang, Yan Li, Hong Shen
Pages: 668-674
Published online on: 28 November 2011

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Article

Atorvastatin inhibits collar-induced intimal thickening of rat carotid artery: Effect on C-type natriuretic peptide expression

Yongjie Li, Yuan Gao, Dingyin Zeng
Pages: 675-679
Published online on: 09 December 2011

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Article

Effects of lithium on oxidative stress parameters in healthy subjects

Rushaniya Khairova, Rohit Pawar, Giacomo Salvadore, Mario F. Juruena, Rafael T. de Sousa, Márcio G. Soeiro-de-Souza, Mirian Salvador, Carlos A. Zarate, Wagner F. Gattaz, Rodrigo Machado-Vieira
Pages: 680-682
Published online on: 22 December 2011

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Article

Butylated hydroxyanisole affects immunomodulation and promotes macrophage phagocytosis in normal BALB/c mice

Fang-Ming Hung, Ying-Ying Chuang, Ching-Sung Lee, Yung-Liang Chen, Jai-Sing Yang, Jen-Jyh Lin, Kung-Wen Lu, Hui-Ying Huang, Chien-Chih Yu, Hsu-Feng Lu, Jing-Gung Chung
Pages: 683-687
Published online on: 12 December 2011

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Article

Differential blood lipid-lowering effects of alkylsulfonated chitosan of different molecular weights in Syrian hamsters in vivo

Chih-Chung Wu, Shan-Ying Lin, Chi-Tsai Chen, Yueh-Ping Chang, Yun-Shsan Huang, Chong-Kuei Lii, Chien-Chih Yu, Shu-Ling Hsieh, Jing-Gung Chung
Pages: 688-694
Published online on: 12 December 2011

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Article

Downregulation of Dicer, a component of the microRNA machinery, in bladder cancer

Deyao Wu, Jun Tao, Bin Xu, Pengchao Li, Qiang Lu, Wei Zhang
Pages: 695-699
Published online on: 14 December 2011

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Article

E-cadherin and 5-HT alterations in the heart of rats having undergone atropine-induced toxicity

Quan-Yong Huang, Xue-Fang Li, Shui-Ping Liu
Pages: 700-704
Published online on: 20 December 2011

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Article

E-cadherin and caveolin-1 alterations in the heart of rats having undergone chlorpromazine-induced toxicity

Quan-Yong Huang, Xue-Fang Li, Shui-Ping Liu
Pages: 705-709
Published online on: 20 December 2011

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Article

α-enolase and caveolin alterations in the heart of rats having undergone gentamicin-induced toxicity

Quan-Yong Huang, Xue-Fang Li, Shui-Ping Liu
Pages: 710-714
Published online on: 20 December 2011

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Article

Enhancement of enterohemorrhagic Escherichia coli O157:H7 stress tolerance via pre-heating

Masanori Nakano, Youko Itoh, Yoshiaki Yamada, Kogenta Nakamura, Makoto Sumitomo, Masakazu Nitta
Pages: 715-720
Published online on: 09 December 2011

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Article

Antiplatelet, anticoagulant and fibrinolytic effects of Litchi chinensis Sonn. extract

Yoon-Young Sung, Won-Kyung Yang, Ho Kyoung Kim
Pages: 721-724
Published online on: 22 December 2011

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Article

Increased FGFR1 copy number in lung squamous cell carcinomas

Hidefumi Sasaki, Masayuki Shitara, Keisuke Yokota, Yu Hikosaka, Satoru Moriyama, Motoki Yano, Yoshitaka Fujii
Pages: 725-728
Published online on: 15 December 2011

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Article

Increased hepatic expression of dipeptidyl peptidase-4 in non-alcoholic fatty liver disease and its association with insulin resistance and glucose metabolism

Masayuki Miyazaki, Masaki Kato, Kosuke Tanaka, Masatake Tanaka, Motoyuki Kohjima, Kazuhiko Nakamura, Munechika Enjoji, Makoto Nakamuta, Kazuhiro Kotoh, Ryoichi Takayanagi
Pages: 729-733
Published online on: 13 December 2011

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Article

Synergistic antitumor interactions between gemcitabine and clofarabine in human pancreatic cancer cell lines

Yingjie Guo, Xuelian Xu, Wenxiu Qi, Chengzhi Xie, Guan Wang, Aijun Zhang, Yubin Ge
Pages: 734-738
Published online on: 23 December 2011

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Article

A novel mono-carbonyl analogue of curcumin induces apoptosis in ovarian carcinoma cells via endoplasmic reticulum stress and reactive oxygen species production

Xie Zhang, Han-Qing Zhang, Guang-Hui Zhu, Yu-Huang Wang, Xi-Chong Yu, Xin-Bo Zhu, Guang Liang, Jian Xiao, Xiao-Kun Li
Pages: 739-744
Published online on: 09 December 2011

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Article

Combination therapy with lentinan improves outcomes in patients with esophageal carcinoma

Ji-Lian Wang, Zheng Bi, Jian-Wen Zou, Xiao-Meng Gu
Pages: 745-748
Published online on: 19 December 2011

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Article

Optimised cord blood sample selection for small‑scale CD34+ cell immunomagnetic isolation

Ana-María Perdomo-Arciniegas, Jean-Paul Vernot
Pages: 749-752
Published online on: 22 December 2011

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Article

miR-143 is downregulated in cervical cancer and promotes apoptosis and inhibits tumor formation by targeting Bcl-2

Lipeng Liu, Xiaohua Yu, Xiaofang Guo, Zhi Tian, Min Su, Yu Long, Chunxia Huang, Feng Zhou, Meiling Liu, Xinhua Wu, Xiaochun Wang
Pages: 753-760
Published online on: 06 December 2011

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Article

Cell growth of BG-1 ovarian cancer cells is promoted by di-n-butyl phthalate and hexabromocyclododecane via upregulation of the cyclin D and cyclin-dependent kinase-4 genes

Min-Ah Park, Kyung-A Hwang, Hye-Rim Lee, Bo-Rim Yi, Eui-Bae Jeung, Kyung-Chul Choi
Pages: 761-766
Published online on: 15 December 2011

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Article

Chondrogenic differentiation of canine myoblasts induced by cartilage-derived morphogenetic protein-2 and transforming growth factor-β1 in vitro

Yanglin Gu, Yubin Wang, Hongjian Dai, Liangyu Lu, Yan Cheng, Wenhui Zhu
Pages: 767-772
Published online on: 15 December 2011

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Article

Activation of MAP kinase family members triggered by TPA or ionomycin occurs via the protein phosphatase 4 pathway in Jurkat leukemia T cells

Eduardo Parra
Pages: 773-778
Published online on: 19 December 2011

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Article

Musculoskeletal manifestation in the joints of the diabetic animal model Otsuka Long-Evans Tokushima Fatty rat: A histological study

Kyoung Soo Kim, In-Kyung Jeong, Sang-Hoon Lee, Ran Song, Hyung-In Yang, Jung Yeon Kim
Pages: 779-782
Published online on: 20 December 2011

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Article

Matrine inhibits proliferation and induces apoptosis of the androgen‑independent prostate cancer cell line PC-3

Peng Zhang, Ziming Wang, Tie Chong, Zongzheng Ji
Pages: 783-787
Published online on: 09 December 2011

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Article

Antitumor and anti-angiogenic activities of Scutellaria barbata extracts in vitro are partially mediated by inhibition of Akt/protein kinase B

Zhihui Zhao, Lori Holle, When Song, Yanzhang  Wei, Thomas E. Wagner, Xianzhong Yu
Pages: 788-792
Published online on: 06 December 2011

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Article

In vitro inhibition of influenza virus infection by a crude extract from Isatis indigotica root resulting in the prevention of viral attachment

Zifeng Yang, Yutao Wang, Shan Zhong, Suishan Zhao, Xiangteng Zeng, Ziyao Mo, Sheng Qin, Wenda Guan, Chuyuan Li, Nanshan Zhong
Pages: 793-799
Published online on: 13 December 2011

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Article

Suppression of microRNA-96 expression inhibits the invasion of hepatocellular carcinoma cells

Rong-Xin Chen, Yun-Hong Xia, Tong-Chun Xue, Sheng-Long Ye
Pages: 800-804
Published online on: 06 December 2011

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Article

Pro-angiogenic activity of astragaloside IV in HUVECs in vitro and zebrafish in vivo

Yi Zhang, Guang Hu, Shang Li, Zhen Hua Li, Che Oi Lam, Si-Jia Hong, Yiu‑Wa  Kwan, Shun Wan Chan, George Pak-Heng Leung, Simon Ming-Yuen Lee
Pages: 805-811
Published online on: 15 December 2011

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Article

Down-regulation of P-glycoprotein expression contributes to an increase in Danshensu accumulation in the cerebral ischemia/reperfusion brain

Yating Chong, Tian Wang, Wenyan Wang, Leiming Zhang, Chong Li, Pengfei Yu, Hongsheng Wang, Fenghua Fu
Pages: 812-816
Published online on: 28 November 2011

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Article

Correlation of E-cadherin and CD44v6 expression with clinical pathology in esophageal carcinoma

Wei-Dong Shen, Yong Ji, Peng-Fei Liu, Bin Xiang, Guo-Qiang Chen, Bin Huang, Song Wu
Pages: 817-821
Published online on: 02 December 2011

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Article

Anticancer effect and apoptosis induction by quercetin in the human lung cancer cell line A-549

Shi-Ying Zheng, Yin Li, Dong Jiang, Jun Zhao, Jin-Feng Ge
Pages: 822-826
Published online on: 20 December 2011

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Article

Celecoxib suppresses fibroblast proliferation and collagen expression by inhibiting ERK1/2 and SMAD2/3 phosphorylation

Fengfeng Li, Cunyi Fan, Bingfang Zeng, Changqing Zhang, Yimin Chai, Shen Liu, Yuanming Ouyang
Pages: 827-831
Published online on: 19 December 2011

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Article

Solitary huge hepatocellular carcinomas 10 cm or larger may be completely ablated by repeated radiofrequency ablation combined with chemoembolization: Initial experience with 9 patients

Shan Ke, Xuemei Ding, Jun Gao, Kun Gao, Xiaojun Qian, Baoxing Cao, Mingying Li, Wenbing Sun
Pages: 832-836
Published online on: 13 December 2011

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Article

Hypolipidemic effects of kaempferide-7-O-(4''-O-acetylrhamnosyl)-3-O-rutinoside in hyperlipidemic rats induced by a high-fat diet

Xue-Zhong Zhao, Xu-Wen Li, Yong-Ri Jin, Xiao-Feng Yu, Shao-Chun Qu, Da-Yuan Sui
Pages: 837-841
Published online on: 15 December 2011

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Article

Nanog inhibits lipopolysaccharide-induced expression of pro-inflammatory cytokines by blocking NF-κB transcriptional activity in rat primary microglial cells

Haitao Zhou, Shiyan Chen, Wei Wang, Zhiqiang Wang, Xiuli Wu, Zhijian Zhang
Pages: 842-846
Published online on: 19 December 2011

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Article

Sulforaphane protects against 6-hydroxydopamine-induced cytotoxicity by increasing expression of heme oxygenase-1 in a PI3K/Akt-dependent manner

Chang Deng, Ran Tao, Shun-Zhi Yu, Hua Jin
Pages: 847-851
Published online on: 21 December 2011

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Article

Effects of bpV(pic) and bpV(phen) on H9c2 cardiomyoblasts during both hypoxia/reoxygenation and H2O2-induced injuries

Youqing Tian, Abdelkader Daoud, Jing Shang
Pages: 852-858
Published online on: 22 December 2011

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Article

Feasibility study for epidemic prevention and control in a regional hospital

Yung-Liang Chen, Ming-Yang Yeh, Shau-Yen Huang, Chi-Ming Liu, Chi-Chen  Sun, Hsu-Feng Lu, Tsan-Hung Chiu, Te-Chun Hsia, Jing-Gung Chung
Pages: 859-865
Published online on: 21 December 2011

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Article

RNAi-mediated ERBB2 gene knockdown sensitizes human colorectal cancer cells to radiation

Dong-Li Zhao, Cheng-Xue Dang, Yan-Xia Sui
Pages: 866-872
Published online on: 20 December 2011

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Article

Effect of hirudin on the levels of acute lung injury rat tumor necrosis factor-α and matrix metalloproteinase-12

Yongxia Bao, Ying Geng, Hui Jing
Pages: 873-875
Published online on: 27 December 2011

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Journal Cover
February-2026 Volume 33 Issue 2

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

ISX promotes tumor migration and invasion in lung cancer by upregulating COL1A1 in vitro

Yihe Ma, Ye Chen, Yuhui Liang, Yun Huang, Miao Gong, Lifeng Tian, Xiaojun Xiao, Jingyan Liu, Qinmiao Huang
Article Number: 77
Published online on: 31 December 2025

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Article Open Access

Role and mechanism of miR‑222‑5p in endothelial cell apoptosis

Shimeng Wang, Boxin Zhao, Ying Cui, Lin Gui, Jingyao Fan, Lijuan Huang
Article Number: 76
Published online on: 31 December 2025

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Expression of Concern Open Access

[Expression of Concern] MicroRNA-29c inhibits proliferation and promotes apoptosis in non-small cell lung cancer cells by targeting VEGFA

Shijuan Zhan, Chunfeng Wang, Fangqing Yin
Article Number: 75
Published online on: 22 December 2025

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Article Open Access

Melatonin induces autophagy in neuroblastoma by alleviating Pak2‑mediated endoplasmic reticulum stress

Qian-Qi Qiu, Na Zhang, Ying-Yi Xu, Jing-Wen Qin, Gao-Feng Yu, Xing-Rong Song
Article Number: 74
Published online on: 22 December 2025

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Article Open Access

ST3Gal1 modulates intestinal barrier function and impacts human ulcerative colitis

Yin Tian, Yun Liu, Yangyang Shang, Lijian Ran, Li Liu, Rongquan Wang, Jun Ye
Article Number: 73
Published online on: 18 December 2025

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Article Open Access

Mechanistic study of miR‑369‑3p in regulating the Wnt/β‑catenin signaling pathway via targeting SPTBN1 in inflammatory response and bone destruction of rheumatoid arthritis

Aihong Wu, Yuan Wang, Feifei Liu, Zhoufang Cao, Shuhui Du, Mengyu Sun
Article Number: 72
Published online on: 18 December 2025

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Article Open Access

CACNB1 alleviates mepivacaine‑induced myocardial ischemia/reperfusion injury by promoting Nrf2 nuclear translocation

Qingbo Shao, Ji Zhang, Huaying Wang
Article Number: 71
Published online on: 17 December 2025

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Expression of Concern Open Access

[Expression of Concern] Effects of cullin 4B on the proliferation and invasion of human gastric cancer cells

Feng He, Xiu-Mei Cheng, Wen-Long Gu
Article Number: 70
Published online on: 17 December 2025

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Article Open Access

Aggravated effects of human parvovirus B19 NS1 protein on bleomycin‑induced pulmonary fibrosis

Tsai-Ching Hsu, Chih-Chen Tzang, Chia-Wei Kuo, Zhi-Han Wen, Der-Yuan Chen, Bor-Show Tzang
Article Number: 69
Published online on: 16 December 2025

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Review Open Access

Advances regarding the mechanism of endoplasmic reticulum stress in diabetic kidney disease and pharmacological interventions (Review)

Pai Zhang, Yabin Cui, Chunyan Liu, Chengji Cui, Shoulin Zhang, Yue Zhang, Fan Li
Article Number: 68
Published online on: 16 December 2025

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Retraction Open Access

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis

Jie Huang, Zhou Wu, Guangxiu Wang, Yingxian Cai, Minshan Cai, Yaozhang Li
Article Number: 67
Published online on: 15 December 2025

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Review Open Access

Deciphering epigenetic regulation in cardiac developmental toxicity: Mechanisms and implications (Review)

Ziling Qin, Ranran Chen, Dianrong Song
Article Number: 66
Published online on: 11 December 2025

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Review Open Access

Gut microbiota as a multifaceted modulator of prostate cancer: Mechanistic insights, therapeutic opportunities and clinical challenges (Review)

Zhenming Hao, Yongqiang Xie, Ru Zhang, Hui Sang, Luxi Li, Yulin Liu, Jinbo Hu, Jijun Wang, Keqiang Chai, Qiang Zhao
Article Number: 65
Published online on: 11 December 2025

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Expression of Concern Open Access

[Expression of Concern] lncRNA FLVCR1‑AS1 drives colorectal cancer progression via modulation of the miR‑381/RAP2A axis

Yi Han, Xiaoyan Wang, Enqiang Mao, Boyong Shen, Liang Huang
Article Number: 64
Published online on: 10 December 2025

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Review Open Access

Influence and treatment of insulin receptor substrate/PI3K/Akt‑mediated insulin resistance in diabetes mellitus (Review)

Weikang Tang, Huixia Liu, Xuan Li, Siyao Deng, Changyu Gao
Article Number: 63
Published online on: 09 December 2025

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Retraction Open Access

[Retracted] Long non‑coding RNA ANRIL knockdown suppresses apoptosis and pro‑inflammatory cytokines while enhancing neurite outgrowth via binding microRNA‑125a in a cellular model of Alzheimer’s disease

Bingling Zhou, Lijuan Li, Xin Qiu, Jiashun Wu, Lei Xu, Wei Shao
Article Number: 62
Published online on: 08 December 2025

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Review Open Access

Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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Article Open Access

ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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Article

MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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Correction Open Access

[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Article Open Access

Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Article Open Access

Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Review Open Access

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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Article Open Access

lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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Retraction Open Access

[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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March-2026 Volume 33 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Advances in the mechanisms of the NLRP3 inflammasome in sepsis‑induced cardiomyopathy and targeted therapeutic studies 
(Review)

Yifei Chen, Zhaohui Zhang, Gaosheng Zhou
Article Number: 98
Published online on: 22 January 2026

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Article Open Access

HMGN2 induces pyroptosis in tumour cells by modulating the STT3B/PD‑L1/caspase‑1/GSDMD axis

Wenwen Han, Hongli Chen, Bomiao Cui, Jiao Chen, Ping Zhang, Yun Feng
Article Number: 97
Published online on: 22 January 2026

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Article Open Access

Naringin ameliorates intestinal injury in ulcerative colitis model mice by modulating the JAK2/STAT3 signaling pathway

Miaomiao Wu, Yating An, Yongmin Li, Wei He, Ying Wang, Yaqi Wang, Caixia Wu
Article Number: 96
Published online on: 22 January 2026

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Review

PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)

Chen Zhou, Yifei Wang, Jie Zhao, Yantao Yang, Yuhang Yuan, Xiaochen Hou, Yu Tang, Lianhua Ye
Article Number: 95
Published online on: 22 January 2026

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Retraction Open Access

[Retracted] Autophagy flux inhibition mediated by celastrol sensitized lung cancer cells to TRAIL‑induced apoptosis via regulation of mitochondrial transmembrane potential and reactive oxygen species

Uddin Md Nazim, Honghua Yin, Sang-Youel Park
Article Number: 94
Published online on: 19 January 2026

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Review Open Access

Converting ‘cold’ to ‘hot’ hepatocellular carcinoma for improved immunotherapy (Review)

Ching-Hua Hsieh, Pei-Chin Chuang
Article Number: 93
Published online on: 15 January 2026

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Article Open Access

Pathological mechanism of ferroptosis in a rat model of α‑naphthyl isothiocyanate‑induced chronic cholestasis

Zhen Guo, Jiaxuan Wang, Yiwen Wang, Xinzhu Liu, Yubing Xia, Ping Liu, Li Qi, Jia Liu, Xiaoning Wang
Article Number: 92
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] Role of hypoxia‑inducible factor‑1α and CD146 in epidermal growth factor receptor‑mediated angiogenesis in salivary gland adenoid cystic carcinom

Wei-Ming Wang, Zhi-Li Zhao, Wen-Feng Zhang, Yi-Fang Zhao, Lu Zhang, Zhi-Jun Sun
Article Number: 91
Published online on: 13 January 2026

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Review Open Access

Klebsiella pneumoniae and pyogenic liver abscess: Emerging clinical threats, virulence mechanisms and therapeutic strategies (Review)

Gulam Mustafa Hasan, Taj Mohammad, Sobia Zaidi, Anas Shamsi, Sukhwinder Singh Sohal, Md. Imtaiyaz Hassan
Article Number: 90
Published online on: 13 January 2026

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Article Open Access

Collagen III regulates the termination of liver regeneration by suppressing hepatocyte proliferation and promoting functional recovery

Haiyang Peng, Zhiyong Chen, Qiwei Zhang, Yuezhou Zhang, Peng Yang, Jianping Gong, Andong Zhao
Article Number: 89
Published online on: 13 January 2026

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Review Open Access

Application of extracellular vesicles in the diagnosis and treatment of chronic obstructive pulmonary disease (Review)

Yixin Zhang, Tong Ren, Jianbo Xue, Yan Yu, Xianqiang Zhou, Xiaoyi Hu, Wenyi Yu, Zhancheng Gao, Cuiling Feng
Article Number: 88
Published online on: 13 January 2026

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Article Open Access

Cigarette smoke combined with Klebsiella pneumoniae induce damage to the air‑blood barrier in chronic obstructive pulmonary disease rats via the MAPK/NF‑κB/IκBα pathway

Yange Tian, Kexin Xu, Ruilong Lu, Kangchen Li, Xuejie Shao, Yixi Liao, Yakun Zhao, Zhiguang Qiu, Haoran Dong, Xuefang Liu
Article Number: 87
Published online on: 12 January 2026

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Retraction Open Access

[Retracted] 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells

Qing Ding, Yi Chen, Qing Zhang, Yanling Guo, Zhi Huang, Liqing Dai, Sudan Cao
Article Number: 86
Published online on: 12 January 2026

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Article Open Access

Anxiety‑induced overactive bladder: The role of oxidative stress and NF‑κB signaling pathway with Hsp90 as a potential biomarker

Zhipeng Zhou, Lina Xu, Han Wu, Huaishan Hong
Article Number: 85
Published online on: 12 January 2026

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Article Open Access

Echinacoside alleviates asthenozoospermia by upregulating Sox5‑mediated transcriptional activation of the CatSper gene

Zi-Run Jin, Yong-Wei Huo, Bo-Heng Liu, Hong Tian, Shuo Yuan, Yue Tian, Ke Xi, Jie Cai, Hui Jiang, Yong Jiang, Guo-Gang Xing
Article Number: 84
Published online on: 12 January 2026

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Article Open Access

Artemisiae Scopariae Herba (Yinchen) suppresses ferroptosis in mice with osteoporosis via the Nrf2/Slc7a11/Gpx4 pathway

Pei Li, Xinyu Wan, Wenjie Li, Ding Cheng, Ying Yang, Yuhan Wang, Ruyuan Zhu, Yanjing Chen, Haixia Liu, Zhiguo Zhang
Article Number: 83
Published online on: 12 January 2026

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Review Open Access

Prolyl hydroxylase domain proteins: Localization, regulation, function and their role in erythropoiesis (Review)

Yan Hou, Zhao-Hua Zhang, Wen-Qian Li, Guo-Xiong Han, Kuo Shen, You-Bang Xie
Article Number: 82
Published online on: 12 January 2026

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Review Open Access

Therapeutic potential of saponins for allergic rhinitis: Molecular mechanisms and clinical perspectives (Review)

Bing-Yu Liang, Zi-Yue Fu, Fen-Fen Li, Ping-Ting Zhou, Zi-Hui Xie, Ke Han, Yan-Xun Han, Shan-Wen Chen, Yi Zhao, Hai-Feng Pan, Ye-Hai Liu, Yu-Chen Liu
Article Number: 81
Published online on: 07 January 2026

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Review Open Access

Interleukin‑6 and ischemic stroke: From mechanisms to clinical prospects (Review)

Xinyue Wang, Xiaohang Zhang, Jianing Lin, Ping Lin
Article Number: 80
Published online on: 05 January 2026

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Article Open Access

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma

Ru Chen, Jie Xu
Article Number: 79
Published online on: 05 January 2026

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Retraction Open Access

[Retracted] TIPE‑2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3‑kinase/AKT signaling pathway

Lin Wang, Chen Chen, Shuzhi Feng, Jianli Tian
Article Number: 78
Published online on: 05 January 2026

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