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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
December 2012 Volume 6 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

Clinical implementation of chromosomal microarray technology in prenatal diagnosis (Review)

Ji Un Kang, Sun Hoe Koo
Pages: 1219-1222
Published online on: 04 October 2012

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Article Open Access

Chromogranin A cell density in the rectum of patients with irritable bowel syndrome

M. El-Salhy, T. Mazzawi, D. Gundersen, T. Hausken
Pages: 1223-1225
Published online on: 18 September 2012

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Article

CD151 promotes cancer cell metastasis via integrins α3β1 and α6β1 in vitro

Yujie Fei, Ji Wang, Weifeng Liu, Houjuan Zuo, Jin Qin, Daowen Wang, Hesong Zeng, Zhengxiang Liu
Pages: 1226-1230
Published online on: 24 September 2012

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Article

The Salvia miltiorrhiza monomer IH764-3 induces apoptosis of hepatic stellate cells in vivo in a bile duct ligation-induced model of liver fibrosis

Lei Liu, Juan Wei, Xiaoxia Huo, Shuming Fang, Dongmei Yao, Junping Gao, Huiqing Jiang, Xiaolan Zhang
Pages: 1231-1238
Published online on: 11 September 2012

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Article

Immunogenicity of Cpn0425 and its localization in cells infected with Chlamydophila pneumoniae

Liangzhuan Liu, Xiaoxing You, Liesong Chen, Yanhua Zeng, Shuangyang Tang, Minjun Yu, Yimou Wu, Xi Xhen
Pages: 1239-1242
Published online on: 13 September 2012

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Article

Effects of SASH1 on melanoma cell proliferation and apoptosis in vitro

Sheyu Lin, Junyu Zhang, Jiawei Xu, Honglian Wang, Qing Sang, Qinghe Xing, Lin He
Pages: 1243-1248
Published online on: 26 September 2012

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Article

Annexin A5 protein expression is associated with the histological differentiation of uterine cervical squamous cell carcinoma in patients with an increased serum concentration

Xin Li, Long Chen, Xiu Jun Liang, Yu Feng Gao, Xiao Jie Wang, Qian Xu, Yong Yan, Fu Lu Gao
Pages: 1249-1254
Published online on: 12 September 2012

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Article

Expression of chemokine CCL20 in ulcerative colitis

Haifeng Zhang, Wane Zhong, Guoxiong Zhou, Xiaoling Ding, Haiqing Chen
Pages: 1255-1260
Published online on: 20 September 2012

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Article

Decreased levels of nitric oxide production and nitric oxide synthase-2 expression are associated with the development and metastasis of hepatocellular carcinoma

Lei Zhou, Ying Wang, De-An Tian, Juan Yang, Yu-Zhen Yang
Pages: 1261-1266
Published online on: 24 September 2012

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Article

Curcumin induces apoptosis of triple-negative breast cancer cells by inhibition of EGFR expression

Xiao-Dong Sun, Xing-E Liu, Dong-Sheng Huang
Pages: 1267-1270
Published online on: 26 September 2012

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Article

C677T methylenetetrahydrofolate reductase gene polymorphism as a risk factor involved in venous thromboembolism: A population-based case-control study

Guancheng Yin, Liqing Yan, Zhifeng Zhang, Kebiao Chen, Xing Jin
Pages: 1271-1275
Published online on: 18 September 2012

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Article

Sublocalization of Rab23, a mediator of Sonic hedgehog signaling pathway, in hepatocellular carcinoma cell lines

Hai-Ji Sun, Yun-Jian Liu, Na Li, Zhi-Yong Sun, Hai-Wang Zhao, Chen Wang, Hui Li, Fang-Ming Ma, Song-Mei Shi, Xiao-Qiu Xu, Zhe-Yu Chen, Shu-Hong Huang
Pages: 1276-1280
Published online on: 20 September 2012

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Article

Angiogenesis in a rat model following myocardial infarction induced by hypoxic regulation of VEGF165 gene-transfected EPCs

Qiang She, Shuang Xia, Song-Bai Deng, Jian-Lin Du, Ye-Qing Li, Li He, Jun Xiao, Yu-Luan Xiang
Pages: 1281-1287
Published online on: 28 September 2012

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Article

Lentiviral vector-mediated RNA interference targeted against prohibitin inhibits apoptosis of the retinoic acid-resistant acute promyelocytic leukemia cell line NB4-R1

Yanfeng Liu, Pengcheng He, Mei Zhang, Di Wu
Pages: 1288-1292
Published online on: 27 September 2012

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Article

Enhancement of gene transfer efficiency in the Bcap-37 cell line by dimethyl sulphoxide and menthol

Jian Lin, Li Qi Zhu, Tao Qin, Qing Hua Yu, Qian Yang
Pages: 1293-1300
Published online on: 17 September 2012

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Article

Altered expression levels of HLA class Ⅱ and costimulatory molecules on circulating monocytes from patients with cervical intraepithelial neoplasia and squamous cervical cancer

Ting Feng, Jian-Hong Zhou, Jia Liu, Feng Ye, Weiguo Lu, Xing Xie
Pages: 1301-1304
Published online on: 10 September 2012

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Article

Mutation of 3β-hydroxysteroid dehydrogenase (3β-HSD) at the 3'-untranslated region is associated with adrenocortical insufficiency

Ying Pan, Shao Zhong, Ren-Ming Hu, Wei Gong
Pages: 1305-1308
Published online on: 28 September 2012

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Article

Plasmid DNA containing multiple CpG motifs triggers a strong immune response to hepatitis B surface antigen when combined with incomplete Freund's adjuvant but not aluminum hydroxide

Zichao Luo, Huashan Shi, Hailong Zhang, Meng Li, Yuwei Zhao, Jing Zhang, Fuchun Guo, Shan Luo, Ping Sun, Dongmei Zhang, Zhiyong Qian, Li Yang
Pages: 1309-1314
Published online on: 12 September 2012

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Article

Protective effects of VEGF treatment on focal cerebral ischemia in rats

Aimei Zhang, Lunan Liang, Huanfu Niu, Peng Xu, Yongnan Hao
Pages: 1315-1318
Published online on: 10 September 2012

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Article

Decreased plasma decorin levels following acute ischemic stroke: Correlation with MMP-2 and differential expression in TOAST subtypes

Yuan-Zhi Xu, Kai-Jun Zhao, Zhi-Gang Yang, Yu-Hui Zhang, Yong-Wei Zhang, Bo Hong, Jian-Min Liu
Pages: 1319-1324
Published online on: 28 September 2012

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Article

Detection of significant pathways in osteoporosis based on graph clustering

Haijun Xiao, Liancheng Shan, Haiming Zhu, Feng Xue
Pages: 1325-1332
Published online on: 13 September 2012

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Article

Propofol increases µ-opioid receptor expression in SH-SY5Y human neuroblastoma cells

Zuojun Li, Qi Pei, Lijun Cao, Linyong Xu, Bikui Zhang, Shikun Liu
Pages: 1333-1336
Published online on: 10 September 2012

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Article

Different patterns of cardiac sympathetic denervation in tremor-type compared to akinetic-rigid-type Parkinson's disease: Molecular imaging with 123I-MIBG

A. Chiaravalloti, A. Stefani, M. Tavolozza, M. Pierantozzi, D. Di Biagio, E. Olivola, B. Di Pietro, M. Stampanoni, R. Danieli, G. Simonetti, P. Stanzione, O. Schillaci
Pages: 1337-1342
Published online on: 27 September 2012

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Article

Naringin inhibits chemokine production in an LPS‑induced RAW 264.7 macrophage cell line

Ying Liu, Wei-Wei Su, Sheng Wang, Pei-Bo Li
Pages: 1343-1350
Published online on: 10 September 2012

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Article

Suramin inhibits the growth of nasopharyngeal carcinoma cells via the downregulation of osteopontin

Shan Jiang, Xiaopin Chen, Chunyan Li, Xingping Zhang, Tao Zhang, Yujuan Yue, Guang Yang
Pages: 1351-1354
Published online on: 10 September 2012

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Article

Induction of non-small cell lung carcinoma apoptosis using soluble RGD-TRAIL by targeting the integrin receptor of tumor cells

Ruyong Yao, Aihua Sui, Zhenli Wang, Shihai Liu, Quan Zhou, Xiangping Liu, Haiping Zhang
Pages: 1355-1360
Published online on: 10 September 2012

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Article

Pingmu decoction enhances apoptosis of orbital adipocytes derived from patients with Graves' ophthalmophathy

Hong Li, Yaqiong Wang, Rongjuan Xu
Pages: 1361-1366
Published online on: 12 September 2012

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Article

Side-effects of resveratrol in HepG2 cells: Reduced pten and increased bcl-xl mRNA expression

Min Zheng, Ruifu Chen, Hongyuan Zhong, Qiuyan Lin, Xiaoqin Wang, Zhiwei Zhao, Linna Xie
Pages: 1367-1370
Published online on: 12 September 2012

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Article

Association of CHKA polymorphism (rs3794186) with α-fetoprotein levels in hepatocellular carcinoma

Min-Su Park, Su Kang Kim, Hyun Phil Shin, Sang Mok Lee, Joo-Ho Chung
Pages: 1371-1374
Published online on: 12 September 2012

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Article

Construction of a DNA vaccine based on the Mycobacterium tuberculosis Ag85A/MPT64 fusion gene and evaluation of its immunogenicity

Hong Bao, Ting Yu, Yufen Jin, Chunyan Teng, Ximing Liu, Yanlei Li
Pages: 1375-1378
Published online on: 28 September 2012

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Article

Insulin upregulates the expression of zinc finger and BTB domain-containing 7A in HepG2 cells

Jing Tian, Yuyang Jiang
Pages: 1379-1384
Published online on: 01 October 2012

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Article

Polymorphisms of the IL-18 promoter and bronchial asthma

Song-Quan Wu, Wei Liang, Guang-Li Wang, Ling-Yun Li, Dan-Li Wang, Cong Chen
Pages: 1385-1388
Published online on: 26 September 2012

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Article

Correlation between polymorphisms of nicotine acetylcholine acceptor subunit CHRNA3 and lung cancer susceptibility

Bo Shen, Mei-Qi Shi, Ma-Qing Zheng, Sai-Nan Hu, Jia Chen, Ji-Feng Feng
Pages: 1389-1392
Published online on: 26 September 2012

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Article

Mitochondrial DNA damage and its effect on mitochondrial function in rats with obstructive jaundice

Chun Tang, Heng Lin, Chun-Lin Feng, Qiao Wu, Yu-Jun Zhang, Ping Bie
Pages: 1393-1398
Published online on: 01 October 2012

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Article

The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. V. Post-mortem findings

Zoheir Mellouk, Karim Louchami, Emeline Hupkens, Abdullah Sener, Dalila Ait Yahia, Willy J. Malaisse
Pages: 1399-1403
Published online on: 20 September 2012

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Article

The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. VI. Further post-mortem investigations

Zoheir Mellouk, Emeline Hupkens, Marie-Helene Antoine, Abdullah Sener, Dalila Ait Yahia, Willy J. Malaisse
Pages: 1404-1408
Published online on: 20 September 2012

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Article

The metabolic syndrome of fructose-fed rats: Effects of long-chain polyunsaturated ω3 and ω6 fatty acids. VII. Oxidative stress

Zoheir Mellouk, Abdullah Sener, Dalila Ait Yahia, Willy J. Malaisse
Pages: 1409-1412
Published online on: 20 September 2012

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Article

Effect of recombinant adeno-associated BMP‑4/7 fusion gene on the biology of BMSCs

Shao-Hui Yuan, Zhenggang Bi
Pages: 1413-1417
Published online on: 20 September 2012

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Article

Regulation of glucose transporter protein-1 and vascular endothelial growth factor by hypoxia inducible factor 1α under hypoxic conditions in Hep-2 human cells

Ou Xu, Xiaoming Li, Yongtao Qu, Shuang Liu, Jie An, Maoxin Wang, Qingjia Sun, Wen Zhang, Xiuying Lu, Lihong Pi, Min Zhang, Yupeng Shen
Pages: 1418-1422
Published online on: 11 September 2012

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Article

Glucose-regulated protein 75 overexpression attenuates ionizing radiation-mediated injury in PC12 cells by inducing the expression of topoisomerase IIα

Weiwei Guo, Ling Yang, Hua Li, Zuojun Xie, Wen Liu, Ji Zuo
Pages: 1423-1427
Published online on: 10 September 2012

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Article

Characterization of insulin-producing cells derived from PDX-1-transfected neural stem cells

Hailan Wang, Zesheng Jiang, Aihui Li, Yi Gao
Pages: 1428-1432
Published online on: 20 September 2012

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Article

IGF-1 activates the P13K/AKT signaling pathway via upregulation of secretory clusterin

Xiumei Ma, Yongrui Bai
Pages: 1433-1437
Published online on: 28 September 2012

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Article

Cytokine expression and the role of Th17 cells in a mouse model of colitis

Ying He, Lian-Jie Lin, Chang-Qing Zheng, Yu Jin, Yan Lin
Pages: 1438-1442
Published online on: 28 September 2012

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Article

Antitumor actions of baicalein and wogonin in HT-29 human colorectal cancer cells

So-Jung Kim, Hyeong-Jin Kim, Hye-Ri Kim, Seung-Ho Lee, Sung-Dae Cho, Chang-Sun Choi, Jeong-Seok Nam, Ji-Youn Jung
Pages: 1443-1449
Published online on: 17 September 2012

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Article

Expression of APP, BACE1, AChE and ChAT in an AD model in rats and the effect of donepezil hydrochloride treatment

Qiang Li, Min Chen, Hongmin Liu, Liqun Yang, Guiying Yang
Pages: 1450-1454
Published online on: 26 September 2012

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Article

In vivo and in vitro evidence of the neurotoxic effects of ropivacaine: The role of the Akt signaling pathway

Zhihua Sun, Huining Liu, Qulian Guo, Xiaoping Xu, Zhong Zhang, Na Wang
Pages: 1455-1459
Published online on: 01 October 2012

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Article

Optimization of transfection parameters for ultrasound/Sonovue microbubble-mediated hAng-1 gene delivery in vitro

Qing Zhou, Jin-Ling Chen, Qian Chen, Xiao Wang, Qing Deng, Bo Hu, Rui-Qiang Guo
Pages: 1460-1464
Published online on: 26 September 2012

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Article

Transforming growth factor-β3 intron 5 polymorphism as a screening marker for non-syndromic cleft lip with or without cleft palate

Korkut Ulucan, Nazli Bayraktar, Emine Parmaksiz, Arzu Akcay, Ahmet Ilter Güney
Pages: 1465-1467
Published online on: 26 September 2012

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Journal Cover
June-2026 Volume 33 Issue 6

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Mechanotransducer Piezo1 drives ventilator‑induced lung injury in lung epithelial cells via the calcineurin/NFATc3 pathway

Min Li, Shu-Li Zhang, Feng Yuan, Dan Feng
Article Number: 183
Published online on: 28 April 2026

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Review Open Access

Oncogene c‑Myc: From molecular mechanism to targeted therapy (Review)

Jianjun Lu, Jing Zhu, Liqiong Zhang, Xiang Zheng, Shan Yang, Yatong Sang, Mingli Yang, Yu Tang
Article Number: 182
Published online on: 28 April 2026

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Article Open Access

Indium (III) chloride inhibits testicular Leydig cell proliferation by disrupting centrosome copy numbers

Chia-Yih Wang, Ping-Jui Su, Kuan-Chih Wang, Ruei-Ci Lin, Min-Yun Ke, Yen-Ni Teng
Article Number: 181
Published online on: 28 April 2026

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Correction Open Access

[Corrigendum] Inhibition of DNA‑PK activity sensitizes A549 cells to X‑ray irradiation by inducing the ATM‑dependent DNA damage response

Lina Yang, Xinrui Yang, Yiwei Tang, Defu Zhang, Lijie Zhu, Shengnan Wang, Bo Wang, Tao Ma
Article Number: 180
Published online on: 27 April 2026

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Review Open Access

Natural products and neurocognitive disorders: Mechanistic insights and research advances (Review)

Weiqing Li, Wei Wu, Xiaoqing Huang, Yinghai Liu, Gu Gong, Qingqing Huang
Article Number: 179
Published online on: 27 April 2026

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Review Open Access

Research progress and future directions in circadian rhythms for uterine‑related diseases (Review)

Tiantian Ma, Junwei Li, Yi Fang, Tiancheng Xu, Qian Li, Liangjun Xia, Youbing Xia
Article Number: 178
Published online on: 27 April 2026

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Review Open Access

Therapeutic potential of tertiary lymphoid structures in breast cancer (Review)

Liangxiao Zhu, Meigui Li, Feng Liu, Fenghou Gao
Article Number: 177
Published online on: 24 April 2026

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Retraction Open Access

[Retracted] Prognostic and predictive roles of microRNA‑411 and its target STK17A in evaluating radiotherapy efficacy and their effects on cell migration and invasion via the p53 signaling pathway in cervical cancer

Wei Wei, Cun Liu
Article Number: 176
Published online on: 22 April 2026

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Review Open Access

Insights into nuciferine: A natural multifunctional bioactive alkaloid (Review)

Yulin Liu, Xinye Li, Bo Huang, Xudong Lai, Baoqing Ye, Haixiong Miao, Lixian Zhang, Xifeng Xiong
Article Number: 175
Published online on: 22 April 2026

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Article

Urinary 8‑OHdG and MDA as rapid biodosimetry markers in the lethal/sublethal dose range

Satoru Monzen, Kenji Terada, Yusuke Tawata, Takanori Sato, Nozomi Kousaka, Yasushi Mariya
Article Number: 174
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Treatment with harmine ameliorates functional impairment and neuronal death following traumatic brain injury  

Zeqi Zhong, Yuan Tao, Hui Yang
Article Number: 173
Published online on: 20 April 2026

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Article Open Access

SRSF1 as a promising biomarker and key player in the pathogenesis of Alzheimer's disease

Yanchen Liu, Yi Zhao, Yanting Yao, Dan Liu, Yilei Sun, Weishi Xu, Hongli Yu, Lijun Chi
Article Number: 172
Published online on: 17 April 2026

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Article Open Access

RUVBL1 and CRAF promote periodontal ligament stem cell osteogenic differentiation via the MEK/ERK signaling cascade

Xin-Yu Zhang, Peiqi Hao, Ming-Yue Qi, Hui Guo
Article Number: 171
Published online on: 16 April 2026

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Article Open Access

Porphyromonas gingivalis triggers lipid metabolism disorders in atherosclerosis through the PPARγ-LXRα‑ABCA1/ABCG1 signaling pathway

Xue-Jing Lin, Min Yao, Wan-Yun Lin, Qin Yuan, Jie Zhou, Wen-Xuan Xia, Yu-Lei Dong, Miao-Miao Zhang, Ming-Wang Cui, Lin-Han Wu, Diwas Sunchuri, Muhammad Zia Ullah Shahid, Zhu-Ling Guo
Article Number: 170
Published online on: 16 April 2026

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Correction Open Access

[Corrigendum] MicroRNA‑122 acts as tumor suppressor by targeting TRIM29 and blocking the activity of PI3K/AKT signaling in nasopharyngeal carcinoma in vitro

Yan Yang, Qing Li, Lili Guo
Article Number: 169
Published online on: 15 April 2026

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Elevated IgG levels induce an M2‑to‑M1 phenotypic shift in mucosal macrophages and restrict the growth of invasive sphenoid sinus pituitary adenomas

Xingbo Li, Zhuowei Lei, Sihan Li, Linpeng Xu, Quanji Wang, Qian Jiang, Zihan Wang, Huaqiu Zhang, Yimin Huang, Ting Lei
Article Number: 168
Published online on: 14 April 2026

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Retraction Open Access

[Retracted] SUMO1/UBC9‑decreased Nox1 activity inhibits reactive oxygen species generation and apoptosis in diabetic retinopathy

Jiaoli Hu, Pengcheng Xue, Xinbang Mao, Lin Xie, Guodong Li, Zhipeng You
Article Number: 167
Published online on: 14 April 2026

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Review Open Access

Potential for anti‑angiogenic therapy targeting the receptor for advanced glycation end products/VEGF axis in ulcerative colitis (Review)

Chen Xu, Yuting Li, Yahua Hong, Dayong Zhou, Kun He, Lianghui Wang, Feng Hong
Article Number: 166
Published online on: 09 April 2026

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Retraction Open Access

[Retracted] Molecular mechanisms underlying mangiferin‑induced apoptosis and cell cycle arrest in A549 human lung carcinoma cells

Wei Shi, Jiagang Deng, Rongsheng Tong, Yong Yang, Xia He, Jianzhen Lv, Hailian Wang, Shaoping Deng, Ping Qi, Dingding Zhang, Yi Wang
Article Number: 165
Published online on: 07 April 2026

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Review Open Access

Mechanism of and research progress on alterations in the RET gene in thyroid cancer (Review)

Meng Wei, Rui Wang, Jincan Qian, Qiang Fang, Jun Tao
Article Number: 164
Published online on: 02 April 2026

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Review Open Access

Current research progress on extracellular vesicles derived from mesenchymal stem cells in tuberculosis treatment (Review)

Dejun Fan, Yan Yang, Li Yang
Article Number: 163
Published online on: 01 April 2026

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Article Open Access

Uremic toxin p‑cresyl sulfate enhances the calcification of aortic valvular interstitial cells via klotho/sirtuin‑1 signaling

Shao-Jung Li, Tzu-Yu Cheng, Yu-Hsun Kao, Wei-Yu Chen, Cheng-Chih Chung, Nguyen Ngoc Trang, Pao-Huan Chen, Yi-Jen Chen
Article Number: 162
Published online on: 01 April 2026

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Review Open Access

Exercise‑induced extracellular vesicle microRNA regulates physiological function (Review)

Zhonglei Wang, Wenjue Guo, Haojia He, Yi Zhang, Na Li
Article Number: 161
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Electroacupuncture at GV20‑GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis

Ruiqiao Guan, Zhihao Li, Xiaohong Dai, Wei Zou, Xueping Yu, Hao Liu, Qiuxin Chen, Wei Teng, Peng Liu, Xiaoying Liu, Shanshan Dong
Article Number: 160
Published online on: 01 April 2026

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Review Open Access

Emerging roles of POLR2L of RNA polymerase II dynamics and disease mechanisms (Review)

Beomwoo Lee, Changgyu Son, Sunho Eom, Yuwen Li, Seon-Hwan Kim, Jongsun Park
Article Number: 159
Published online on: 30 March 2026

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Article Open Access

Combining bioinformatics prediction with experimental validation to explore the ameliorative effect of Psoralea corylifolia on vitiligo

Chen Zhang, Zhanhong Cao, Mengyang Wei, Xuanxuan Zhu, Yan Yan, Zhenhua Wang, Meng Zhang
Article Number: 158
Published online on: 30 March 2026

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Retraction Open Access

[Retracted] All‑trans‑retinoic acid inhibits chondrogenesis of rat embryo hindlimb bud mesenchymal cells by down­regulating p53 expression

Tao-Gen Zhang, Xue-Dong Li, Guo-Yong Yu, Peng Xie, Yun-Guo Wang, Zhao-Yong Liu, Quan Hong, De-Zhong Liu, Shi-Xin Du
Article Number: 157
Published online on: 30 March 2026

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July-2026 Volume 34 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Targeting lipophagy in atherosclerosis: Molecular mechanisms, pathogenesis and therapeutic interventions (Review)

Songhua Nan, Chaojie Peng, Xue Meng, Jingnan Jia, Fangfang Zhao, Yinglin Cui
Article Number: 208
Published online on: 22 May 2026

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Mechanisms of pruritus and advances in traditional Chinese medicine therapy (Review)

Hailing Zhang, Yongji Li, Yuan Liu, Danyi Feng, Letao Zhao, Ran Chen, Xiwu Zhang, Jinjin Dou
Article Number: 207
Published online on: 22 May 2026

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Reprogramming of the hepatic ubiquitin‑immune axis: A unifying mechanism in liver disease progression (Review)

Yadi Ju, Xiaodan Chong, Weichen Ning, Yan Shi, Yangyang Li, Yihai Shi
Article Number: 206
Published online on: 22 May 2026

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Role of the PI3K/AKT signaling pathway in regulating gene expression in rheumatoid arthritis (Review)

Chengzhi Cong, Yuan Wang, Jian Liu, Chao Jin
Article Number: 205
Published online on: 21 May 2026

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Biomarkers of radioresistance in lung cancer: Current insights and future directions (Review)

Fatima Zohra Attouahri, Imane Chaoui, Abdelilah Laraqui, Mohamed Rida Tagajdid, Mohammed Oukabli, Mohammed El Marjany, Meriem Khyatti, Mohammed Attaleb, Mouna Ababou, Khalid Ennibi, Khaoula Errafii, Mohammed El Mzibri
Article Number: 204
Published online on: 21 May 2026

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Epigenetic research methods and animal models for intervertebral disc degeneration (Review)

Xinliang Cui, Li Zeng, Wei Zhang, Leimin Xi, Rui Wang, Diff Jia, Safa, Haoyu Feng, Huidong Jia
Article Number: 203
Published online on: 21 May 2026

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ZBTB16 upregulation maintains copper homeostasis to support esophageal tumor progression

Jingyi Wang, Bin Yang, Shengzu Peng
Article Number: 202
Published online on: 21 May 2026

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Correction Open Access

[Corrigendum] MicroRNA‑1 promotes cartilage matrix synthesis and regulates chondrocyte differentiation via post‑​transcriptional suppression of Ihh expression  

Taoyu Chen, Xianda Che, Pengfei Han, Jiangong Lu, Chunfang Wang, Bin Liang, Ziqi Hou, Xiaochun Wei, Lei Wei, Pengcui Li
Article Number: 201
Published online on: 20 May 2026

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Estrogen deficiency as a common driver and integrative mechanism in osteoporosis‑osteoarthritis comorbidity (Review)

Jian Cheng, Xiaodong Wu, Lu Zhao, Shuai Jiang, Wenjie Zhao, Weishuai Zhang
Article Number: 200
Published online on: 20 May 2026

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Review Open Access

Role of RNA 5‑methylcytosine modification in cancer: Insights from coding and non‑coding RNAs (Review)

Qin Jiang, Yi Gong, Mimi Zhai, Tenglong Tang, Sushun Liu
Article Number: 199
Published online on: 20 May 2026

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m6A modification in skeletal system diseases (Review)

Xi Xie, Chen Li, Haotian Zheng, Guang Gan, Xi Gao
Article Number: 198
Published online on: 19 May 2026

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Review Open Access

Dynamic regulation of the ‘mitochondria‑immune axis’ in myocardial infarction: Molecular mechanisms driving macrophage polarization through energy metabolism disorders (Review)

Yu Zhang, Hao Feng, Qin Wu, Shuxian Yang, Yundong Jiang, Houping Xu, Li Dong, Xiaolin Li, Hui Chen, Gang Luo
Article Number: 197
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Homeobox B9 facilitates hypertrophic scar formation via activating the mitogen‑activated protein kinase signaling pathway

Qun Xie, Dandan Liu, Mosheng Yu, Xiaowei Wu, Yueqiang Zhao, Qiang Hu, Qi Wang
Article Number: 196
Published online on: 18 May 2026

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Review Open Access

Polysaccharides: Natural candidates for targeting immunometabolic regulation in hepatocellular carcinoma (Review)

Changmei Wu, Jinjin Dou, Xiwu Zhang
Article Number: 195
Published online on: 18 May 2026

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Article Open Access

NF‑κB signaling drives Th17‑mediated lacrimal gland injury and tear dysfunction in a murine model of primary Sjögren's syndrome

Jiajun Xie, Huina Zhang, Wenyue Shen, Juan Ye
Article Number: 194
Published online on: 18 May 2026

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Review Open Access

POSTN(+) fibroblasts and SPP1(+) macrophages in scar formation: A review of mechanisms and therapeutic targets (Review)

Haotian Wu, Xianglin Dong
Article Number: 193
Published online on: 15 May 2026

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Review Open Access

Emerging role of DYRK1A as a target in cardiovascular diseases (Review)

Liqing Yu, Qionghong Cheng, Jun Wu
Article Number: 192
Published online on: 15 May 2026

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Retraction Open Access

[Retracted] Resveratrol pretreatment attenuates traumatic brain injury in rats by suppressing NLRP3 inflammasome activation via SIRT1

Peng Zou, Xiaoxiao Liu, Gang Li, Yangang Wang
Article Number: 191
Published online on: 05 May 2026

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Review Open Access

Gut microbiota and its metabolites: Key factors of drug resistance in the treatment of advanced prostate cancer (Review)

Jingheng Song, Hongguo Cui, Peisen Yang, Yankai Xu, Yuanyuan Liu, Gang Zhang, Yangyang Liu, Aimin Tian, Jizhong Che, Hui Sun, Zhengchao Zhang
Article Number: 190
Published online on: 04 May 2026

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Article Open Access

Cepharanthine inhibits lysosomes and induces apoptosis in triple‑negative breast cancer cells

Juan Li, Siqin Zhou, Yu Wang, Guanghan Ou, Danli Yang, Liwen Shen
Article Number: 189
Published online on: 04 May 2026

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Review Open Access

Applications of humanized mice in Mycobacterium tuberculosis infections (Review)

Binghua Han, Fang Liu, Jinzhao Long, Jiongjiong Wang, Yange Cui, Haiyan Yang
Article Number: 188
Published online on: 04 May 2026

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Review Open Access

Research progress on neutrophil extracellular traps in sepsis‑induced coagulopathy (Review)

Jiandong Hu, Mengli Jin, Zhihua Cao, Binbin Zheng, Yuan Zheng, Hao Shen
Article Number: 187
Published online on: 04 May 2026

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Review Open Access

Multifaceted regulatory role of proline‑ and glutamine-rich splicing factor in tumors (Review)

Shilin Zhang, Zhenhua Li, Li Fu
Article Number: 186
Published online on: 04 May 2026

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Article Open Access

Effects of ALDH2 gene expression on the oxidative stress‑mediated NF‑κB/mTOR pathway in ketamine‑induced cystitis

Xiao Jian Xi, Yong Yao, Peng Gu, Min Hao Zhang
Article Number: 185
Published online on: 04 May 2026

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Retraction Open Access

[Retracted] Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury

Junchao Yao, Kebin Zheng, Xiang Zhang
Article Number: 184
Published online on: 29 April 2026

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