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Molecular Medicine Reports
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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2013 Volume 7 Issue 3

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Analysis of the effect of integrons on drug-resistant Staphylococcus aureus by multiplex PCR detection

Chunfeng Ren, Yongjing Zhao, Yan Shen
Pages: 719-724
Published online on: 21 January 2013

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Article Open Access

Downregulation of GRP78 and XIAP is correlated with apoptosis during cerulein-induced acute pancreatitis in rats via regulation of caspase activation

Yong Liu, Zong-Guang Zhou, Bing Zhou, Rong Wang, Hui Yan, Yuan Li
Pages: 725-730
Published online on: 18 December 2012

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Article Open Access

Deregulation of lipid metabolism pathway genes in nasopharyngeal carcinoma cells

Maelinda Daker, Saatheeyavaane Bhuvanendran, Munirah Ahmad, Kenzo Takada, Alan Soo‑Beng Khoo
Pages: 731-741
Published online on: 28 December 2012

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Article

Evaluation of the effect of glucosamine administration on biomarkers of cartilage and bone metabolism in bicycle racers

Rei Momomura, Kiyohito Naito, Mamoru Igarashi, Taiji Watari, Atsuhiko Terakado, Shinji Oike, Koji Sakamoto, Isao Nagaoka, Kazuo Kaneko
Pages: 742-746
Published online on: 25 January 2013

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Article

Protective effect of Cordyceps polysaccharide on hydrogen peroxide-induced mitochondrial dysfunction in HL-7702 cells

Yunxia Liu, Qiukai E, Ji Zuo, Yanyan Tao, Wen Liu
Pages: 747-754
Published online on: 21 December 2012

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Article

Identification of PCAG1 as a novel prostate cancer-associated gene

Yongqing Lai, Zuhu Yu, Yadong Wang, Jiongxian Ye
Pages: 755-760
Published online on: 24 December 2012

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Article

Salivary lncRNA as a potential marker for oral squamous cell carcinoma diagnosis

Haikuo Tang, Zhiyuan Wu, Jianping Zhang, Bing Su
Pages: 761-766
Published online on: 28 December 2012

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Article

Prevalence and spectrum of GJA5 mutations associated with lone atrial fibrillation

Hai-Feng Shi, Jie-Fu Yang, Qian Wang, Ruo-Gu Li, Ying-Jia Xu, Xin-Kai Qu, Wei-Yi Fang, Xu Liu, Yi-Qing Yang
Pages: 767-774
Published online on: 28 December 2012

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Article

Clinical evaluation of the levels of 12 cytokines in serum/plasma under various storage conditions using evidence biochip arrays

Guang‑Hong Guo, Jin Dong, Xin‑Hong Yuan, Zhen‑Nan Dong, Ya‑Ping Tian
Pages: 775-780
Published online on: 04 January 2013

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Article

Antiproliferative activity of daidzein and genistein may be related to ERα/c-erbB-2 expression in human breast cancer cells

Eun Jeong Choi, Gun-Hee Kim
Pages: 781-784
Published online on: 21 January 2013

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Article

Suppression of cell proliferation and collagen production in cultured human hypertrophic scar fibroblasts by Sp1 decoy oligodeoxynucleotide

Chenliang Deng, Jianghong Zheng, Weidong Wan, Shixin Zhang, Zhi Ding, Guangyu Mao, Songlin Yang
Pages: 785-790
Published online on: 18 January 2013

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Article

microRNA expression profiling and bioinformatic analysis of dengue virus‑infected peripheral blood mononuclear cells

Yiming Qi, Ying Li, Lin Zhang, Junqi Huang
Pages: 791-798
Published online on: 24 January 2013

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Article

Effects of cyclin E gene silencing on the proliferation of esophageal cancer cell lines, EC9706, Eca109 and KYSE30 Retraction in /10.3892/mmr.2018.8406

Na Wang, Min Li, Wen-Qiao Zang, Yun-Yun Ma, Yuan-Yuan Wang, Guo-Qiang Zhao
Pages: 799-804
Published online on: 18 January 2013

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Article

Immunosuppression induced by apoptosis of mixed lymphocyte culture is associated with p53

Fuling Wei, Yongmei Cao, Mengran Zhang, Rui Huang, Jun Cheng, Guoan Xiang, Jinqian Zhang
Pages: 805-810
Published online on: 28 January 2013

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Article

Cyclin D1 G870A polymorphism and risk of colorectal cancer: A case control study

Aga Syed Sameer, Fazl Q. Parray, Manzoor Ahmad Dar, Saniya Nissar, Mujeeb Zafar Banday, Sabha Rasool, G. M. Gulzar, Nissar A. Chowdri, Mushtaq A. Siddiqi
Pages: 811-815
Published online on: 24 January 2013

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Article

Protective effect of nicorandil on hypoxia‑induced apoptosis in HPAECs through inhibition of p38 MAPK phosphorylation

Yanzhe Yu, Yonglong Xiao, Hui Wang, Junyang Li, Xiangrong Zuo, Hong Wang, Weiping Xie
Pages: 816-820
Published online on: 02 January 2013

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Article

SOX9 overexpression plays a potential role in idiopathic congenital talipes equinovarus

Zhengdong Wang, Nan Yan, Liying Liu, Donghua Cao, Ming Gao, Changkun Lin, Chunlian Jin
Pages: 821-825
Published online on: 19 December 2012

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Article

The NS3 protease and helicase domains of Japanese encephalitis virus trigger cell death via caspase‑dependent and ‑independent pathways

Giou‑Teng Yiang, Yen‑Hsieh Chen, Pei‑Lun Chou, Wei‑Jung Chang, Chyou‑Wei Wei, Yung‑Luen Yu
Pages: 826-830
Published online on: 03 January 2013

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Article

Sulodexide may alleviate neointimal hyperplasia by inhibiting angiopoietin‑2 in an arteriovenous fistula model

Yan Lei, Zhihua Zheng, Ying Wang, Yuyun Liu, Rongjun Liu, Qingdong Xu, Xueqing Yu
Pages: 831-835
Published online on: 28 January 2013

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Article

The tetraspanin CD151-ARSA mutant inhibits angiogenesis via the YRSL sequence Corrigendum in /10.3892/mmr.2023.13069

Dan Peng, Houjuan Zuo, Zhengxiang Liu, Jin Qin, Yuanlin Zhou, Pengcheng Li, Daowen Wang, Hesong Zeng, Xin A. Zhang
Pages: 836-842
Published online on: 24 December 2012

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Article

Silencing of the human SET gene in vitro with lentivirus-mediated RNA interference

Yanfeng Liu, Pengcheng He, Mei Zhang, Lili Shi, Huachao Zhu, Yuan Wang, Jing Zhao
Pages: 843-847
Published online on: 15 January 2013

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Article

Qianliening capsule treats benign prostatic hyperplasia via induction of prostatic cell apoptosis

Haiyin Zheng, Wei Xu, Jiumao Lin, Jun Peng, Zhenfeng Hong
Pages: 848-854
Published online on: 07 January 2013

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Article

Palmitate induces H9c2 cell apoptosis by increasing reactive oxygen species generation and activation of the ERK1/2 signaling pathway

Chuan‑Dong Wei, Yan Li, Hong‑Yun Zheng, Yong‑Qing Tong, Wen Dai
Pages: 855-861
Published online on: 16 January 2013

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Article

The expression and role of peroxisome proliferator-activated receptor α in atherosclerosis

Wen Gao, Wei Xu, Hongli Li
Pages: 862-868
Published online on: 21 January 2013

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Article

Survival of pig-to-rhesus corneal xenografts prolonged by prior donor bone marrow transplantation

Ying Jie, Limin Liu, Zhiqiang Pan, Li Wang
Pages: 869-874
Published online on: 28 January 2013

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Article

Silencing of periostin inhibits nicotine-mediated tumor cell growth and epithelial-mesenchymal transition in lung cancer cells

Shu-Qiang Wu, Ya-Er Lv, Bai-Hua Lin, Li-Min Luo, Shi-Liang Lv, Ai-Hong Bi, Yong-Shi Jia
Pages: 875-880
Published online on: 09 January 2013

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Article

Protein profiling of paraquat-exposed rat lungs following treatment with Acai (Euterpe oleracea Mart.) berry extract

Yong-Sik Kim, Hana Jung, Tamanna Zerin, Ho-Yeon Song
Pages: 881-886
Published online on: 03 January 2013

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Article

Effects of stromal cell-derived factor-1 and survivin gene polymorphisms on gastric cancer risk

Emmanouil Liarmakopoulos, George Theodoropoulos, Anna Vaiopoulou, Spyros Rizos, Gerasimos Aravantinos, Gregory Kouraklis, Nikolaos Nikiteas, Maria Gazouli
Pages: 887-892
Published online on: 21 December 2012

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Article

The effect of mitotane on viability, steroidogenesis and gene expression in NCI‑H295R adrenocortical cells

Tomasz P. Lehmann, Tomasz Wrzesiński, Paweł P. Jagodziński
Pages: 893-900
Published online on: 18 December 2012

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Article

Effect of CYP3A4*18B polymorphisms and interactions with OPRM1 A118G on postoperative fentanyl requirements in patients undergoing radical gastrectomy

Qin Liao, Dao-Jin Chen, Fan Zhang, Li Li, Rong Hu, Yong‑Zhong Tang, Wen Ou‑Yang, Dong Huang
Pages: 901-908
Published online on: 11 January 2013

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Article

Direct regulation of caspase‑3 by the transcription factor AP‑2α is involved in aspirin‑induced apoptosis in MDA‑MB‑453 breast cancer cells

Feng Yan, Qiongzhi He, Xiang Hu, Wen Li, Ke Wei, Li Li, Yingli Zhong, Xiaofeng Ding, Shuanglin Xiang, Jian Zhang
Pages: 909-914
Published online on: 02 January 2013

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Article

Alpinetin promotes Bax translocation, induces apoptosis through the mitochondrial pathway and arrests human gastric cancer cells at the G2/M phase

Zhenran Wang, Wenjing Lu, Yang Li, Bo Tang
Pages: 915-920
Published online on: 18 December 2012

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Article

Silencing of triggering receptor expressed on myeloid cells-2 enhances the inflammatory responses of alveolar macrophages to lipopolysaccharide

Xiaoling Gao, Yanting Dong, Zhuola Liu, Bo Niu
Pages: 921-926
Published online on: 10 January 2013

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Article

Genetic association analysis of CIITA variations with nasal polyp pathogenesis in asthmatic patients

Joon Seol Bae, Charisse Flerida A. Pasaje, Byung Lae Park, Hyun Sub Cheong, Jeong-Hyun Kim, Soo-Taek Uh, Choon-Sik Park, Hyoung Doo Shin
Pages: 927-934
Published online on: 27 December 2012

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Article

Achyranthes bidentata polysaccharides induce chondrocyte proliferation via the promotion of the G1/S cell cycle transition

Fangrong Yu, Xihai Li, Liangliang Cai, Huiting Li, Jiashou Chen, Xiaping Wong, Huifeng Xu, Chunsong Zheng, Xianxiang Liu, Hongzhi Ye
Pages: 935-940
Published online on: 22 January 2013

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Article

Inhibitory effect of nicardipine on rotenone‑induced apoptosis in SH‑SY5Y human neuroblastoma cells

Hae Jeong Park, Hak‑Jae Kim
Pages: 941-946
Published online on: 03 January 2013

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Article Open Access

Hypersensitivity reaction studies of a polyethoxylated castor oil-free, liposome-based alternative paclitaxel formulation

Hongbo Wang, Guang Cheng, Yuan Du, Liang Ye, Wenzhong Chen, Leiming Zhang, Tian Wang, Jingwei Tian, Fenghua Fu
Pages: 947-952
Published online on: 04 January 2013

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Article

Bone morphogenetic protein‑2 enhances the expression of cardiac transcription factors by increasing histone H3 acetylation in H9c2 cells

Min Zheng, Jing Zhu, Tiewei Lv, Lingjuan Liu, Huichao Sun, Jie Tian
Pages: 953-958
Published online on: 09 January 2013

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Article

Recombinant hemangiopoietin promotes cell adhesion and binds heparin in its multimeric form

Li‑Fang Wang, Zhi‑Bo Han, Mei Li, Ping Yang, Bin Xv, Ji‑Ping Zhang, Zhong‑Chao Han
Pages: 959-964
Published online on: 15 January 2013

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Case Report

Clinical and molecular genetic analysis of a new mutation in children with Wolfram syndrome: A case report

Qianqian Xu, Huaiyu Qu, Shihui Wei
Pages: 965-968
Published online on: 17 January 2013

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Article

Overexpression of GPC3 inhibits hepatocellular carcinoma cell proliferation and invasion through induction of apoptosis

Zhijian Pan, Chunzhou Chen, Haocheng Long, Changjiang Lei, Gang Tang, Lei Li, Jiarui Feng, Feixiang Chen
Pages: 969-974
Published online on: 18 January 2013

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Article

Recombinant Ganoderma lucidum immunomodulatory protein modified with polyethylene glycol

Xiping Zhang, Fei Sun, Zhiyi Liu, Shuqin Zhang, Chongyang Liang
Pages: 975-980
Published online on: 18 January 2013

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Article

Differential expression of estradiol and estrogen receptor α in severe preeclamptic pregnancies compared with normal pregnancies

Guowu Yin, Xiaoming Zhu, Chun Guo, Yang Yang, Tao Han, Lei Chen, Wen Yin, Ping Gao, Huizhong Zhang, Jie Geng, Julei Wang, Liang Liang
Pages: 981-985
Published online on: 04 January 2013

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Article

The role of p21 3'UTR gene polymorphism in the risk of prostate cancer: A pilot study

Monika Kmeťová Sivoňová, Marta Vilčková, Jana Jurečeková, Jozef Hatok, Dušan Dobrota, Róbert Dušenka, Ján Kliment
Pages: 986-990
Published online on: 18 December 2012

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Article

ADAM15 is involved in MICB shedding and mediates the effects of gemcitabine on MICB shedding in PANC-1 pancreatic cancer cells

Xiaohui Duan, Xianhai Mao, Weijia Sun
Pages: 991-997
Published online on: 11 January 2013

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Article

Induction of apoptosis by chitosan/HPV16 E7 siRNA complexes in cervical cancer cells

Jun Yang, Shaoping Li, Fang Guo, Wei Zhang, Yonglian Wang, Ying Pan
Pages: 998-1002
Published online on: 20 December 2012

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Article

Chondrogenesis of myoblasts in biodegradable poly-lactide-co-glycolide scaffolds

Yanglin Gu, Peng Chen, Yusheng Yang, Keqin Shi, Yubin Wang, Wenhui Zhu, Guoxing Zhu
Pages: 1003-1009
Published online on: 18 December 2012

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Article

Cytokine profile in relapsing‑remitting multiple sclerosis patients and the association between progression and activity of the disease

Ana Paula Kallaur, Sayonara Rangel Oliveira, Andréa Name Colado Simão, Elaine Regina Delicato de Almeida, Helena Kaminami Morimoto, Josiane Lopes, Wildea  Lice de Carvalho Jennings Pereira, Renato Marques Andrade, Larissa Muliterno Pelegrino, Sueli Donizete Borelli, Damácio  Ramon Kaimen‑Maciel, Edna Maria Vissoci Reiche
Pages: 1010-1020
Published online on: 02 January 2013

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Article

Effect of chronic renal failure medium on the ubiquitin‑proteasome pathway of arterial muscle cells

Yao‑Quan Zhang, Bing Feng, Fa‑Huan Yuan
Pages: 1021-1025
Published online on: 11 January 2013

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Article

ΔNp63 promotes UM‑UC‑3 cell invasiveness and migration through claudin‑1 in vitro

Peng Jing, Jiaqiong Zou, Jun Zhang, Xingliang Jiang
Pages: 1026-1030
Published online on: 11 January 2013

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Article

Increased interleukin‑9 and CD4+IL-9+ T cells in patients with systemic lupus erythematosus

Han Ouyang, Yongbing Shi, Zhichun Liu, Sheng Feng, Lingyun Li, Nan Su, Ying Lu, Shumin Kong
Pages: 1031-1037
Published online on: 02 January 2013

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Article

Deltonin induces apoptosis in MDA‑MB‑231 human breast cancer cells via reactive oxygen species‑mediated mitochondrial dysfunction and ERK/AKT signaling pathways

Shiyuan Zhang, Yang He, Qingyi Tong, Qianming Chen, Xiaohua Wu, Wen Huang
Pages: 1038-1044
Published online on: 11 January 2013

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Article

Tanshinone IIA inhibits the growth of pancreatic cancer BxPC‑3 cells by decreasing protein expression of TCTP, MCL‑1 and Bcl‑xL

Cheng‑Yen Huang, Tsung‑Lang Chiu, Shou‑Jen Kuo, Su‑Yu Chien, Dar‑Ren Chen, Chin‑Cheng Su
Pages: 1045-1049
Published online on: 25 January 2013

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Article

Silencing of integrin-linked kinase suppresses in vivo tumorigenesis of human ovarian carcinoma cells

Qi Li, Chen Li, Yun-Yan Zhang, Wei Chen, Jun-Li Lv, Jing Sun, Qing-Shan You
Pages: 1050-1054
Published online on: 22 January 2013

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Article

Epigenetic inactivation of ADAMTS9 via promoter methylation in multiple myeloma

Ling Peng, Zesong Yang, Cui Tan, Guosheng Ren, Jianbin Chen
Pages: 1055-1061
Published online on: 28 January 2013

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Journal Cover
November-2026 Volume 34 Issue 5

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Research on the role and mechanism of SLC7A5 in idiopathic pulmonary fibrosis

Menghan Wang, Yao Yu, Zhaoyu Liu, Dandan Xu, Yupeng Li, Xing Zou, Ning Shan, Xining Liu, Ce Shi, Hong Chen
Article Number: 323
Published online on: 01 October 2026

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Review Open Access

Electroencephalography research in neuropathic pain (Review)

Lanling Zhou, Nianshun Liao, Hongmei Wang, Jiaxi Zhao, Haijun Jiang, Shihua Dang, Sixun Yu, Haifeng Shu, Xin Chen
Article Number: 322
Published online on: 25 September 2026

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Review Open Access

BMAL1 in cardiovascular diseases: Molecular mechanisms, circadian regulation and translational perspectives (Review)

Yu Liang, Tingjin Chen, Xuemei Wen, Dan Liu, Zhongjian Zhang, Weiqing Li, Hengdi Zhang
Article Number: 321
Published online on: 24 September 2026

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Review Open Access

Progress on quinoline‑based antitumour agents: Mechanistic insights and optimization strategies (Review)

Yuwen Zeng, Yutong Yan, Shiye Wu, Wanshan Wu, Ke Chen, Youyi Lai, Qing Ye, Nan Zhang, Yuanyuan Zhou
Article Number: 320
Published online on: 23 September 2026

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Review Open Access

Lactylation in gastric cancer: From mechanisms to clinical applications (Review)

Yuliang Fang, Peng Chen, Yuhong Gao, Yanpiao Li, Xue Li
Article Number: 319
Published online on: 23 September 2026

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Article Open Access

Sleep deprivation exacerbates lens‑induced myopia in association with ERK/NF‑κB pathway activation

Xueli Yang, Zhou Zhang, Chengbai Zhu, Jianbo Li, Wenting Gong, Ruirui Yang, Lipeng Guan
Article Number: 318
Published online on: 22 September 2026

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Review Open Access

Advances in biomarkers of benzene exposure and toxicity: From mechanistic insights to occupational health applications (Review)

Yuanshe Huang, Zhenjun Xi, Jingxin Mao, Xiaobing Li
Article Number: 317
Published online on: 21 September 2026

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Retraction Open Access

[Retracted] CALB1 enhances the interaction between p53 and MDM2, and inhibits the senescence of ovarian cancer cells

Long-Qiao Cao, Ya-Nan Wang, Ming Liang, Mei-Zhou Pan
Article Number: 316
Published online on: 21 September 2026

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Review Open Access

Artemisinin and its derivatives for metabolic syndrome: From multi‑target mechanisms to translational opportunities (Review)

Shuo Cao, Mo Yang, Siyu Qu, Jinsong Wu, Jiaheng Li, Ying Zhao
Article Number: 315
Published online on: 17 September 2026

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Article Open Access

Demethylase FTO attenuates atherosclerotic plaque via upregulating ABCA1 and ABCG1 expression by targeting ATG5

Fengxia Guo, Mei He, Yaonan Li, Kangning Zhu, Bing Hu
Article Number: 314
Published online on: 16 September 2026

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Correction Open Access

[Corrigendum] Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development

Ziyue Li, Guoqing Chen, Yaling Yang, Weihua Guo, Weidong Tian
Article Number: 313
Published online on: 16 September 2026

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Review Open Access

Integrin αVβ3 as a context‑dependent regulator of bone homeostasis: Insights into osteoporosis pathogenesis and therapeutic targeting (Review)

Changshun Chen, Xingxi Hu, Sixing Wei, Yongcheng Deng, Qinggang Zhao, Ge Chen, Zhong Cheng, Jianhua Ji, Jinyi Gu
Article Number: 312
Published online on: 15 September 2026

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Article Open Access

Therapeutic effects of exosome‑based hyperin delivery in a cyclophosphamide‑induced mouse model of diminished ovarian reserve

Yi Ying, Yue Wu, Ji Zhou, Yaming Wang, Hongtao Yin, Gang Lu, Ruolang Pan, Liangzhong Lv
Article Number: 311
Published online on: 15 September 2026

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Review Open Access

Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review)

Xin Dong, Yongkun Hou, Jingjing Shao, Haixia Zhu, Jibin Liu
Article Number: 310
Published online on: 15 September 2026

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Review Open Access

Mitochondria‑associated endoplasmic reticulum membranes in degenerative musculoskeletal disorders: Mechanistic evidence and therapeutic perspectives (Review)

Shilong Meng, Xinlei Fu, Yawei Xu, Zhiliang Peng, Xu Zhang, Yanguang Cao, Binbin Tang, Xiaolin Shi, Kang Liu
Article Number: 309
Published online on: 15 September 2026

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Article Open Access

High‑fat diet exacerbates hepatic and adipose insulin signaling impairment and ovarian lesions in a rat model of letrozole‑induced polycystic ovary syndrome

Sunju So, Sujin Kwon, La Yoon Choi, Dae Yong Kim, Mi Hye Kim
Article Number: 308
Published online on: 15 September 2026

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Retraction Open Access

[Retracted] RNAi‑mediated A disintegrin and metalloproteinase 9 gene silencing inhibits the tumor growth of non‑small lung cancer in vitro and in vivo

Liang Chang, Fangchao Gong, Youbin Cui
Article Number: 307
Published online on: 14 September 2026

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Article Open Access

A four‑gene signature identifies TKI‑induced persister cells and uncovers a ZLN005‑induced pyroptotic vulnerability via the GSDME pathway in EGFR‑mutant lung cancer

Wenwen Chang, Jiaxin Yuan, Huilin Zhang, Ying Yu, Yan Ma, Mingyue Li, Wenjing Li, Hongxia Yan, Chongran Sun, Peng Zhang, Yang Tian, Feng Guo, Pan Li, Yang Sun
Article Number: 306
Published online on: 11 September 2026

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Review Open Access

Research advances in the microbiota‑gut‑brain axis and Parkinson's disease (Review)

Yangping Meng, Qian Liu, Hao Zou, Xingyu Zhu, Xinxin Mi, Sitong Li, Yutian Xia, Yucheng Ma, Qianyu Yang, Jiaxin Peng, Junrui Li, Xingliang Liu, Junli Chen
Article Number: 305
Published online on: 10 September 2026

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Article Open Access

Ameliorative effects of Paulownia tomentosa flower absolute on atopic dermatitis‑related responses in mast cells and keratinocytes and its chemical composition

Da Yeon Yoo, Kyung Jong Won, Do Yoon Kim, Yoon Yi Kim, Ji Hye Bae, Ji Seong Yun, Hwan Myung Lee
Article Number: 304
Published online on: 10 September 2026

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Retraction Open Access

[Retracted] PYGB siRNA inhibits the cell proliferation of human osteosarcoma cell lines

Shuwei Zhang, Yichi Zhou, Yuanyu Zha, Yang Yang, Linlong Wang, Jingfeng Li, Wei Jin
Article Number: 303
Published online on: 10 September 2026

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Article Open Access

KIF4A drives esophageal squamous cell carcinoma via Wnt/β‑catenin signaling and predicts poor prognosis

Jialong Chen, Tong Wang, Da Wang, Weiguo Liu, Chunlai Liu, Yang Yang, Xiangfu Sun, Lei Zhou
Article Number: 302
Published online on: 08 September 2026

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Review Open Access

Research progress of aptamers in the diagnosis and treatment of colorectal cancer (Review)

Yiwen Li, Penghui Yan, Ji Zhang, Binghui Wu, Min Li, Baoliang Bao
Article Number: 301
Published online on: 08 September 2026

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Review Open Access

Role of the circadian rhythm in squamous cell carcinoma: From molecular mechanism to therapy (Review)

Mary-Lyn Eichhorn, Anna M. Dmitrieva, Lydia Meder
Article Number: 300
Published online on: 08 September 2026

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Expression of Concern Open Access

[Expression of Concern] Ganoderma lucidum polysaccharide inhibits prostate cancer cell migration via the protein arginine methyltransferase 6 signaling pathway

Xiaohui Zhao, Dayu Zhou, Yunen Liu, Chun Li, Xiaoguang Zhao, Ying Li, Wei Li
Article Number: 299
Published online on: 07 September 2026

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Review Open Access

Multi‑omics approaches to decipher the molecular mechanisms of exercise‑mediated bone protection: From mechanistic insights to personalized exercise prescription (Review)

Bin Tian, Xuesong Chen, Xin Kang
Article Number: 298
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] MicroRNA‑27a promotes tumorigenesis via targeting AKT in triple negative breast cancer

Jing Wu, Zhihui Sun, Huijie Sun, Yanhua Li
Article Number: 297
Published online on: 03 September 2026

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December-2026 Volume 34 Issue 6

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Journal Metrics

Impact Factor: 5.0

CiteScore: 7.3

CiteScore Rank: Q1: #83/351 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Mechanisms of the interaction between aging of the male reproductive system and obesity, and clinical management strategies (Review)

Dandan Luo, Lulu Zhang, Xiangyu Qi, Qiangbo Guan, Feng Xu, Peng Lu, Chunxiao Yu
Article Number: 340
Published online on: 22 October 2026

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Erythropoietin beyond red blood cells: Systemic and oncological functions (Review)

Kristína Danková, Zuzana Solárová, Pavol Harvanik, Martina Šemeláková, Peter Solár
Article Number: 339
Published online on: 22 October 2026

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Liquid‑liquid phase separation and post‑transcriptional regulation intersection: A new paradigm of RNA‑binding protein condensates in hepatocellular carcinoma malignant phenotypes (Review)

Xiao Liu, Yunyi Huang
Article Number: 338
Published online on: 21 October 2026

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Research advances in the interplay between ferroptosis and T cells in the tumor microenvironment (Review)

Shihan Tang, Wenbo Xu, Yichen Li, Chuwei Liu, Weitao Liu, Ruihan Liang, Qianhui Liao, Han Sun, Zhuoyan Wang, Lingchang Shi, Qiying Liu, Huiping Liu
Article Number: 337
Published online on: 21 October 2026

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Review Open Access

Gut‑kidney axis in chronic kidney disease: Dysbiosis, uremic metabolites and therapeutic opportunities (Review) 

Yinding Wang, Hanyu Zeng, Na Liu, Dong Yang
Article Number: 336
Published online on: 16 October 2026

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Article Open Access

Glycyrrhizic acid attenuates corneal inflammation and pathological angiogenesis through FAK/PI3K/AKT signaling

Jinjin Yu, Huiheng Qu, Yinming Fang, Weicheng Xu, Nannan Ding, Jie Ji, Nan Wang, Wei Shi
Article Number: 335
Published online on: 15 October 2026

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Article Open Access

Erbin deficiency exacerbates sepsis‑induced liver injury through mitochondrial ROS/NLRP3‑mediated inflammatory responses

Jing Zuo, Xing Wang, Guoqing Jing, Xiaojing Wu, Xuemin Song
Article Number: 334
Published online on: 15 October 2026

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Review Open Access

Gut microbiota in patients receiving dialysis: Mechanisms, complications and the road to personalized microbiome‑based care (Review)

Chenxia Jin, Yanping Wang
Article Number: 333
Published online on: 15 October 2026

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Article Open Access

Epigallocatechin gallate and thermal cycling‑stimulation synergistically promote apoptosis in A549 cells via endoplasmic reticulum stress‑induced calcium ion dysregulation and oxidative stress

Fang-Tzu Hsu, Hsu-Hsiang Liu, Yi Kung, Chieh-Jou Lin, Chih-Yu Chao
Article Number: 332
Published online on: 15 October 2026

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Article Open Access

Piezo1 knockdown alleviates high‑altitude cerebral edema by improving brain microvascular endothelial cell tight junctions via blocking the calcium influx‑mediated Calpain‑1 activity

Taijian Cao, Zhicheng Xiang, Yangyang Zhao, Drolma Gomchok, Haifeng Ma, Shiwang Li, Dahai Cao, Chunqing Yang, Qiang Zhang
Article Number: 331
Published online on: 13 October 2026

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Navigating the landscape of targeted therapies for renal cell carcinoma in the era of precision medicine (Review)

Hongguo Cui, Jingheng Song, Peisen Yang, Zhengchao Zhang, Yuanyuan Liu, Gang Zhang, Aimin Tian, Jizhong Che, Yangyang Liu, Hui Sun, Yankai Xu
Article Number: 330
Published online on: 13 October 2026

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Article Open Access

ΔNp63α‑mediated regulation of tumor‑associated genes and pathways in hepatocellular carcinoma progression

Xiaowen Lin, Anghui Peng, Min Zhang, Xinyang Yu
Article Number: 329
Published online on: 13 October 2026

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Article Open Access

 Leptin promotes obesity‑related osteoarthritis progression via CD44/JAK2/STAT3 axis‑mediated chondrocyte apoptosis

Hao Qiu, Chao Zeng, Cheng Chen, Xin Zhou, Yongjun Zhu, Zhongliang Deng
Article Number: 328
Published online on: 09 October 2026

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Review Open Access

Mechanical‑immune feedback regulation in distraction osteogenesis: From mechanotransduction to immune microenvironment remodeling (Review)

Xian Wang, Yuetong Wang, Shixi He, Cheng Ma, Zhengzhong He, Xuanping Huang
Article Number: 327
Published online on: 08 October 2026

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Review Open Access

Research progress in synergistic multimechanism of nanomaterial-mediated neuroinflammatory therapy (Review)

Heng Wang, Pei Yang, Wantao Liu
Article Number: 326
Published online on: 07 October 2026

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Retraction Open Access

[Retracted] (‑)‑Epicatechin protects against myocardial ischemia‑induced cardiac injury via activation of the PTEN/PI3K/AKT pathway

Jia-Wen Li, Xiao-Yun Wang, Xin Zhang, Lei Gao, Li-Feng Wang, Xin-Hua Yin
Article Number: 325
Published online on: 05 October 2026

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Review Open Access

Lactylation and exercise: A molecular link to disease alleviation (Review)

Jian Wang, Lei Wu
Article Number: 324
Published online on: 02 October 2026

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