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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
March 2013 Volume 7 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Article Open Access

Analysis of the effect of integrons on drug-resistant Staphylococcus aureus by multiplex PCR detection

Chunfeng Ren, Yongjing Zhao, Yan Shen
Pages: 719-724
Published online on: 21 January 2013

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Article Open Access

Downregulation of GRP78 and XIAP is correlated with apoptosis during cerulein-induced acute pancreatitis in rats via regulation of caspase activation

Yong Liu, Zong-Guang Zhou, Bing Zhou, Rong Wang, Hui Yan, Yuan Li
Pages: 725-730
Published online on: 18 December 2012

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Article Open Access

Deregulation of lipid metabolism pathway genes in nasopharyngeal carcinoma cells

Maelinda Daker, Saatheeyavaane Bhuvanendran, Munirah Ahmad, Kenzo Takada, Alan Soo‑Beng Khoo
Pages: 731-741
Published online on: 28 December 2012

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Article

Evaluation of the effect of glucosamine administration on biomarkers of cartilage and bone metabolism in bicycle racers

Rei Momomura, Kiyohito Naito, Mamoru Igarashi, Taiji Watari, Atsuhiko Terakado, Shinji Oike, Koji Sakamoto, Isao Nagaoka, Kazuo Kaneko
Pages: 742-746
Published online on: 25 January 2013

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Article

Protective effect of Cordyceps polysaccharide on hydrogen peroxide-induced mitochondrial dysfunction in HL-7702 cells

Yunxia Liu, Qiukai E, Ji Zuo, Yanyan Tao, Wen Liu
Pages: 747-754
Published online on: 21 December 2012

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Article

Identification of PCAG1 as a novel prostate cancer-associated gene

Yongqing Lai, Zuhu Yu, Yadong Wang, Jiongxian Ye
Pages: 755-760
Published online on: 24 December 2012

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Article

Salivary lncRNA as a potential marker for oral squamous cell carcinoma diagnosis

Haikuo Tang, Zhiyuan Wu, Jianping Zhang, Bing Su
Pages: 761-766
Published online on: 28 December 2012

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Article

Prevalence and spectrum of GJA5 mutations associated with lone atrial fibrillation

Hai-Feng Shi, Jie-Fu Yang, Qian Wang, Ruo-Gu Li, Ying-Jia Xu, Xin-Kai Qu, Wei-Yi Fang, Xu Liu, Yi-Qing Yang
Pages: 767-774
Published online on: 28 December 2012

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Article

Clinical evaluation of the levels of 12 cytokines in serum/plasma under various storage conditions using evidence biochip arrays

Guang‑Hong Guo, Jin Dong, Xin‑Hong Yuan, Zhen‑Nan Dong, Ya‑Ping Tian
Pages: 775-780
Published online on: 04 January 2013

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Article

Antiproliferative activity of daidzein and genistein may be related to ERα/c-erbB-2 expression in human breast cancer cells

Eun Jeong Choi, Gun-Hee Kim
Pages: 781-784
Published online on: 21 January 2013

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Article

Suppression of cell proliferation and collagen production in cultured human hypertrophic scar fibroblasts by Sp1 decoy oligodeoxynucleotide

Chenliang Deng, Jianghong Zheng, Weidong Wan, Shixin Zhang, Zhi Ding, Guangyu Mao, Songlin Yang
Pages: 785-790
Published online on: 18 January 2013

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Article

microRNA expression profiling and bioinformatic analysis of dengue virus‑infected peripheral blood mononuclear cells

Yiming Qi, Ying Li, Lin Zhang, Junqi Huang
Pages: 791-798
Published online on: 24 January 2013

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Article

Effects of cyclin E gene silencing on the proliferation of esophageal cancer cell lines, EC9706, Eca109 and KYSE30 Retraction in /10.3892/mmr.2018.8406

Na Wang, Min Li, Wen-Qiao Zang, Yun-Yun Ma, Yuan-Yuan Wang, Guo-Qiang Zhao
Pages: 799-804
Published online on: 18 January 2013

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Article

Immunosuppression induced by apoptosis of mixed lymphocyte culture is associated with p53

Fuling Wei, Yongmei Cao, Mengran Zhang, Rui Huang, Jun Cheng, Guoan Xiang, Jinqian Zhang
Pages: 805-810
Published online on: 28 January 2013

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Article

Cyclin D1 G870A polymorphism and risk of colorectal cancer: A case control study

Aga Syed Sameer, Fazl Q. Parray, Manzoor Ahmad Dar, Saniya Nissar, Mujeeb Zafar Banday, Sabha Rasool, G. M. Gulzar, Nissar A. Chowdri, Mushtaq A. Siddiqi
Pages: 811-815
Published online on: 24 January 2013

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Article

Protective effect of nicorandil on hypoxia‑induced apoptosis in HPAECs through inhibition of p38 MAPK phosphorylation

Yanzhe Yu, Yonglong Xiao, Hui Wang, Junyang Li, Xiangrong Zuo, Hong Wang, Weiping Xie
Pages: 816-820
Published online on: 02 January 2013

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Article

SOX9 overexpression plays a potential role in idiopathic congenital talipes equinovarus

Zhengdong Wang, Nan Yan, Liying Liu, Donghua Cao, Ming Gao, Changkun Lin, Chunlian Jin
Pages: 821-825
Published online on: 19 December 2012

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Article

The NS3 protease and helicase domains of Japanese encephalitis virus trigger cell death via caspase‑dependent and ‑independent pathways

Giou‑Teng Yiang, Yen‑Hsieh Chen, Pei‑Lun Chou, Wei‑Jung Chang, Chyou‑Wei Wei, Yung‑Luen Yu
Pages: 826-830
Published online on: 03 January 2013

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Article

Sulodexide may alleviate neointimal hyperplasia by inhibiting angiopoietin‑2 in an arteriovenous fistula model

Yan Lei, Zhihua Zheng, Ying Wang, Yuyun Liu, Rongjun Liu, Qingdong Xu, Xueqing Yu
Pages: 831-835
Published online on: 28 January 2013

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Article

The tetraspanin CD151-ARSA mutant inhibits angiogenesis via the YRSL sequence Corrigendum in /10.3892/mmr.2023.13069

Dan Peng, Houjuan Zuo, Zhengxiang Liu, Jin Qin, Yuanlin Zhou, Pengcheng Li, Daowen Wang, Hesong Zeng, Xin A. Zhang
Pages: 836-842
Published online on: 24 December 2012

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Article

Silencing of the human SET gene in vitro with lentivirus-mediated RNA interference

Yanfeng Liu, Pengcheng He, Mei Zhang, Lili Shi, Huachao Zhu, Yuan Wang, Jing Zhao
Pages: 843-847
Published online on: 15 January 2013

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Article

Qianliening capsule treats benign prostatic hyperplasia via induction of prostatic cell apoptosis

Haiyin Zheng, Wei Xu, Jiumao Lin, Jun Peng, Zhenfeng Hong
Pages: 848-854
Published online on: 07 January 2013

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Article

Palmitate induces H9c2 cell apoptosis by increasing reactive oxygen species generation and activation of the ERK1/2 signaling pathway

Chuan‑Dong Wei, Yan Li, Hong‑Yun Zheng, Yong‑Qing Tong, Wen Dai
Pages: 855-861
Published online on: 16 January 2013

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Article

The expression and role of peroxisome proliferator-activated receptor α in atherosclerosis

Wen Gao, Wei Xu, Hongli Li
Pages: 862-868
Published online on: 21 January 2013

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Article

Survival of pig-to-rhesus corneal xenografts prolonged by prior donor bone marrow transplantation

Ying Jie, Limin Liu, Zhiqiang Pan, Li Wang
Pages: 869-874
Published online on: 28 January 2013

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Article

Silencing of periostin inhibits nicotine-mediated tumor cell growth and epithelial-mesenchymal transition in lung cancer cells

Shu-Qiang Wu, Ya-Er Lv, Bai-Hua Lin, Li-Min Luo, Shi-Liang Lv, Ai-Hong Bi, Yong-Shi Jia
Pages: 875-880
Published online on: 09 January 2013

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Article

Protein profiling of paraquat-exposed rat lungs following treatment with Acai (Euterpe oleracea Mart.) berry extract

Yong-Sik Kim, Hana Jung, Tamanna Zerin, Ho-Yeon Song
Pages: 881-886
Published online on: 03 January 2013

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Article

Effects of stromal cell-derived factor-1 and survivin gene polymorphisms on gastric cancer risk

Emmanouil Liarmakopoulos, George Theodoropoulos, Anna Vaiopoulou, Spyros Rizos, Gerasimos Aravantinos, Gregory Kouraklis, Nikolaos Nikiteas, Maria Gazouli
Pages: 887-892
Published online on: 21 December 2012

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Article

The effect of mitotane on viability, steroidogenesis and gene expression in NCI‑H295R adrenocortical cells

Tomasz P. Lehmann, Tomasz Wrzesiński, Paweł P. Jagodziński
Pages: 893-900
Published online on: 18 December 2012

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Article

Effect of CYP3A4*18B polymorphisms and interactions with OPRM1 A118G on postoperative fentanyl requirements in patients undergoing radical gastrectomy

Qin Liao, Dao-Jin Chen, Fan Zhang, Li Li, Rong Hu, Yong‑Zhong Tang, Wen Ou‑Yang, Dong Huang
Pages: 901-908
Published online on: 11 January 2013

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Article

Direct regulation of caspase‑3 by the transcription factor AP‑2α is involved in aspirin‑induced apoptosis in MDA‑MB‑453 breast cancer cells

Feng Yan, Qiongzhi He, Xiang Hu, Wen Li, Ke Wei, Li Li, Yingli Zhong, Xiaofeng Ding, Shuanglin Xiang, Jian Zhang
Pages: 909-914
Published online on: 02 January 2013

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Article

Alpinetin promotes Bax translocation, induces apoptosis through the mitochondrial pathway and arrests human gastric cancer cells at the G2/M phase

Zhenran Wang, Wenjing Lu, Yang Li, Bo Tang
Pages: 915-920
Published online on: 18 December 2012

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Article

Silencing of triggering receptor expressed on myeloid cells-2 enhances the inflammatory responses of alveolar macrophages to lipopolysaccharide

Xiaoling Gao, Yanting Dong, Zhuola Liu, Bo Niu
Pages: 921-926
Published online on: 10 January 2013

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Article

Genetic association analysis of CIITA variations with nasal polyp pathogenesis in asthmatic patients

Joon Seol Bae, Charisse Flerida A. Pasaje, Byung Lae Park, Hyun Sub Cheong, Jeong-Hyun Kim, Soo-Taek Uh, Choon-Sik Park, Hyoung Doo Shin
Pages: 927-934
Published online on: 27 December 2012

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Article

Achyranthes bidentata polysaccharides induce chondrocyte proliferation via the promotion of the G1/S cell cycle transition

Fangrong Yu, Xihai Li, Liangliang Cai, Huiting Li, Jiashou Chen, Xiaping Wong, Huifeng Xu, Chunsong Zheng, Xianxiang Liu, Hongzhi Ye
Pages: 935-940
Published online on: 22 January 2013

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Article

Inhibitory effect of nicardipine on rotenone‑induced apoptosis in SH‑SY5Y human neuroblastoma cells

Hae Jeong Park, Hak‑Jae Kim
Pages: 941-946
Published online on: 03 January 2013

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Article Open Access

Hypersensitivity reaction studies of a polyethoxylated castor oil-free, liposome-based alternative paclitaxel formulation

Hongbo Wang, Guang Cheng, Yuan Du, Liang Ye, Wenzhong Chen, Leiming Zhang, Tian Wang, Jingwei Tian, Fenghua Fu
Pages: 947-952
Published online on: 04 January 2013

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Article

Bone morphogenetic protein‑2 enhances the expression of cardiac transcription factors by increasing histone H3 acetylation in H9c2 cells

Min Zheng, Jing Zhu, Tiewei Lv, Lingjuan Liu, Huichao Sun, Jie Tian
Pages: 953-958
Published online on: 09 January 2013

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Article

Recombinant hemangiopoietin promotes cell adhesion and binds heparin in its multimeric form

Li‑Fang Wang, Zhi‑Bo Han, Mei Li, Ping Yang, Bin Xv, Ji‑Ping Zhang, Zhong‑Chao Han
Pages: 959-964
Published online on: 15 January 2013

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Case Report

Clinical and molecular genetic analysis of a new mutation in children with Wolfram syndrome: A case report

Qianqian Xu, Huaiyu Qu, Shihui Wei
Pages: 965-968
Published online on: 17 January 2013

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Article

Overexpression of GPC3 inhibits hepatocellular carcinoma cell proliferation and invasion through induction of apoptosis

Zhijian Pan, Chunzhou Chen, Haocheng Long, Changjiang Lei, Gang Tang, Lei Li, Jiarui Feng, Feixiang Chen
Pages: 969-974
Published online on: 18 January 2013

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Article

Recombinant Ganoderma lucidum immunomodulatory protein modified with polyethylene glycol

Xiping Zhang, Fei Sun, Zhiyi Liu, Shuqin Zhang, Chongyang Liang
Pages: 975-980
Published online on: 18 January 2013

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Article

Differential expression of estradiol and estrogen receptor α in severe preeclamptic pregnancies compared with normal pregnancies

Guowu Yin, Xiaoming Zhu, Chun Guo, Yang Yang, Tao Han, Lei Chen, Wen Yin, Ping Gao, Huizhong Zhang, Jie Geng, Julei Wang, Liang Liang
Pages: 981-985
Published online on: 04 January 2013

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Article

The role of p21 3'UTR gene polymorphism in the risk of prostate cancer: A pilot study

Monika Kmeťová Sivoňová, Marta Vilčková, Jana Jurečeková, Jozef Hatok, Dušan Dobrota, Róbert Dušenka, Ján Kliment
Pages: 986-990
Published online on: 18 December 2012

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Article

ADAM15 is involved in MICB shedding and mediates the effects of gemcitabine on MICB shedding in PANC-1 pancreatic cancer cells

Xiaohui Duan, Xianhai Mao, Weijia Sun
Pages: 991-997
Published online on: 11 January 2013

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Article

Induction of apoptosis by chitosan/HPV16 E7 siRNA complexes in cervical cancer cells

Jun Yang, Shaoping Li, Fang Guo, Wei Zhang, Yonglian Wang, Ying Pan
Pages: 998-1002
Published online on: 20 December 2012

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Article

Chondrogenesis of myoblasts in biodegradable poly-lactide-co-glycolide scaffolds

Yanglin Gu, Peng Chen, Yusheng Yang, Keqin Shi, Yubin Wang, Wenhui Zhu, Guoxing Zhu
Pages: 1003-1009
Published online on: 18 December 2012

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Article

Cytokine profile in relapsing‑remitting multiple sclerosis patients and the association between progression and activity of the disease

Ana Paula Kallaur, Sayonara Rangel Oliveira, Andréa Name Colado Simão, Elaine Regina Delicato de Almeida, Helena Kaminami Morimoto, Josiane Lopes, Wildea  Lice de Carvalho Jennings Pereira, Renato Marques Andrade, Larissa Muliterno Pelegrino, Sueli Donizete Borelli, Damácio  Ramon Kaimen‑Maciel, Edna Maria Vissoci Reiche
Pages: 1010-1020
Published online on: 02 January 2013

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Article

Effect of chronic renal failure medium on the ubiquitin‑proteasome pathway of arterial muscle cells

Yao‑Quan Zhang, Bing Feng, Fa‑Huan Yuan
Pages: 1021-1025
Published online on: 11 January 2013

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Article

ΔNp63 promotes UM‑UC‑3 cell invasiveness and migration through claudin‑1 in vitro

Peng Jing, Jiaqiong Zou, Jun Zhang, Xingliang Jiang
Pages: 1026-1030
Published online on: 11 January 2013

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Article

Increased interleukin‑9 and CD4+IL-9+ T cells in patients with systemic lupus erythematosus

Han Ouyang, Yongbing Shi, Zhichun Liu, Sheng Feng, Lingyun Li, Nan Su, Ying Lu, Shumin Kong
Pages: 1031-1037
Published online on: 02 January 2013

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Article

Deltonin induces apoptosis in MDA‑MB‑231 human breast cancer cells via reactive oxygen species‑mediated mitochondrial dysfunction and ERK/AKT signaling pathways

Shiyuan Zhang, Yang He, Qingyi Tong, Qianming Chen, Xiaohua Wu, Wen Huang
Pages: 1038-1044
Published online on: 11 January 2013

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Article

Tanshinone IIA inhibits the growth of pancreatic cancer BxPC‑3 cells by decreasing protein expression of TCTP, MCL‑1 and Bcl‑xL

Cheng‑Yen Huang, Tsung‑Lang Chiu, Shou‑Jen Kuo, Su‑Yu Chien, Dar‑Ren Chen, Chin‑Cheng Su
Pages: 1045-1049
Published online on: 25 January 2013

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Article

Silencing of integrin-linked kinase suppresses in vivo tumorigenesis of human ovarian carcinoma cells

Qi Li, Chen Li, Yun-Yan Zhang, Wei Chen, Jun-Li Lv, Jing Sun, Qing-Shan You
Pages: 1050-1054
Published online on: 22 January 2013

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Article

Epigenetic inactivation of ADAMTS9 via promoter methylation in multiple myeloma

Ling Peng, Zesong Yang, Cui Tan, Guosheng Ren, Jianbin Chen
Pages: 1055-1061
Published online on: 28 January 2013

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Journal Cover
January-2026 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Article Open Access

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Review Open Access

Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Article Open Access

Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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Article Open Access

TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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