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Print ISSN: 1791-2997 Online ISSN: 1791-3004
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
2014-March Volume 9 Issue 3

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review

The role of claudin‑5 in blood‑brain barrier (BBB) and brain metastases (Review)

Wang Jia, Runchun Lu, Tracey A. Martin, Wen G. Jiang
Pages: 779-785
Published online on: 18 December 2013

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Article

Folate‑polyethylene glycol conjugated carboxymethyl chitosan for tumor‑targeted delivery of 5‑fluorouracil

Hai‑Lang Li, Ya‑Xing He, Qian‑Hong Gao, Guo‑Zhong Wu
Pages: 786-792
Published online on: 23 January 2014

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Article Open Access

Synergism between upregulation of Rab7 and inhibition of autophagic degradation caused by mycoplasma facilitates intracellular mycoplasma infection

Xiaopeng Hu, Jie Yu, Xiang Zhou, Zhaoming Li, Yun Xia, Zhiyong Luo, Yaqun Wu
Pages: 793-800
Published online on: 20 January 2014

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Article Open Access

Grape seed proanthocyanidin extract protects from cisplatin-induced nephrotoxicity by inhibiting endoplasmic reticulum stress-induced apoptosis

Zhaoli Gao, Guangyi Liu, Zhao Hu, Xing Li, Xiangdong Yang, Bei Jiang, Xianhua Li
Pages: 801-807
Published online on: 03 January 2014

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Article

Association of a polymorphism of BTN2A1 with dyslipidemia in community-dwelling individuals

Hideki Horibe, Chikara Ueyama, Tetsuo Fujimaki, Mitsutoshi Oguri, Kimihiko Kato, Sahoko Ichihara, Yoshiji Yamada
Pages: 808-812
Published online on: 16 January 2014

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Article

Increased expression of herpesvirus entry mediator in 1,25‑dihydroxyvitamin D3‑treated mouse bone marrow‑derived dendritic cells promotes the generation of CD4+CD25+Foxp3+ regulatory T cells

Yi Huang, Yan Zhao, Xuemei Ran, Changzheng Wang
Pages: 813-818
Published online on: 18 December 2013

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Article

Store-operated Ca2+ entry mediated regulation of polarization in differentiated human neutrophil-like HL-60 cells under hypoxia

Shuang Ma, Chunqing Cai, Yan Ma, Zhengzhong Bai, Xiaojing Meng, Xinyi Yang, Fei Zou, Rili Ge
Pages: 819-824
Published online on: 13 January 2014

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Article

Survivin promotes the invasion of human colon carcinoma cells by regulating the expression of MMP‑7

Fei Gao, Yuqin Zhang, Feng Yang, Peng Wang, Wenjun Wang, Yan Su, Weiren Luo
Pages: 825-830
Published online on: 14 January 2014

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Article

Cytokine IL‑6 is required in Citrobacter rodentium infection‑induced intestinal Th17 responses and promotes IL‑22 expression in inflammatory bowel disease

Lei Li, Qing‑Guo Shi, Fang Lin, Yu‑Guang Liang, Li‑Jian Sun, Jin‑Song Mu, Yong‑Gang Wang, Hai‑Bin Su, Biao Xu, Cheng‑Cheng Ji, Hui‑Huang Huang, Ke Li, Hui‑Fen Wang
Pages: 831-836
Published online on: 14 January 2014

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Article

Generation of induced pluripotent stem cells using skin fibroblasts from patients with myocardial infarction under feeder-free conditions Retraction in /10.3892/mmr.2014.2272

Jun-Quan Li, Ming Cheng, Wei-Chen Tian, Jian Zhang
Pages: 837-842
Published online on: 07 January 2014

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Article

Sevoflurane postconditioning against cerebral ischemic neuronal injury is abolished in diet-induced obesity: Role of brain mitochondrial KATP channels

Zecheng Yang, Yunbo Chen, Yan Zhang, Yi Jiang, Xuedong Fang, Jingwei Xu
Pages: 843-850
Published online on: 22 January 2014

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Article

Glycoprotein non-metastatic melanoma protein B as a predictive prognostic factor in clear-cell renal cell carcinoma following radical nephrectomy

Caipeng Qin, Zhenhua Liu, Yeqing Yuan, Xiaowei Zhang, Henan Li, Chunfang Zhang, Tao Xu, Xiaofeng Wang
Pages: 851-856
Published online on: 14 January 2014

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Article

In silico search for multi-target therapies for osteoarthritis based on 10 common Huoxue Huayu herbs and potential applications to other diseases

Chun‑Song Zheng, Zhi‑Qiang Zhuang, Xiao‑Jie Xu, Jin‑Xia Ye, Hong‑Zhi Ye, Xi‑Hai Li, Guang‑Wen Wu, Hui‑Feng Xu, Xian‑Xiang Liu
Pages: 857-862
Published online on: 22 January 2014

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Article

Early high volume lung lavage for acute severe smoke inhalation injury in dogs

Fachuan Nie, Dong Su, Ying Shi, Jinmei Chen, Haihui Wang, Wanxiang Qin, Suxia Wang, Yaohua Chen
Pages: 863-871
Published online on: 23 December 2013

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Article

Foreign body response induced by tissue expander implantation

Lingling Sheng, Qingxiong Yu, Feng Xie, Qingfeng Li
Pages: 872-876
Published online on: 27 December 2013

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Article

SUMOylation alterations are associated with multidrug resistance in hepatocellular carcinoma

Yu Qin, Huijing Bao, Yi Pan, Meilin Yin, Yunde Liu, Shangwei Wu, Huikai Li
Pages: 877-881
Published online on: 02 January 2014

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Article

Sirt6 suppresses hepatocellular carcinoma cell growth via inhibiting the extracellular signal‑regulated kinase signaling pathway

Zhi-Gao Zhang, Cheng-Yong Qin
Pages: 882-888
Published online on: 24 December 2013

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Article

Expression of PPAR-γ in adipose tissue of rats with polycystic ovary syndrome induced by DHEA

Yu-Xia Wang, Wei-Jie Zhu, Bao-Guo Xie
Pages: 889-893
Published online on: 14 January 2014

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Article

Impact of the 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene on primary nephrotic syndrome

Yuezhong Luo, Chao Wang, Haitao Tu
Pages: 894-898
Published online on: 17 January 2014

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Article

Local delivery of T-bet shRNA reduces inflammation in collagen II‑induced arthritis via downregulation of IFN-γ and IL-17

Yuan Xue, Yong Yang, Zhaoliang Su, Prince Amoatt Barnie, Dong Zheng, Yun Zhang, Yan Xu, Shengjun Wang, Huaxi Xu
Pages: 899-903
Published online on: 13 January 2014

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Article

Aberrant miRNA expression response to UV irradiation in human liver cancer cells

Gaofeng Liang, Guangda Li, Yanyan Wang, Wanjun Lei, Zhongdang Xiao
Pages: 904-910
Published online on: 15 January 2014

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Article

HIF‑1α silencing suppresses growth of lung adenocarcinoma A549 cells through induction of apoptosis

Hong‑Ying Liao, Gui‑Ping Wang, Shao‑Hong Huang, Yun Li, Song‑Wang Cai, Jian Zhang, Hui‑Guo Chen, Wei‑Bin Wu
Pages: 911-915
Published online on: 22 January 2014

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Article

Overexpression of aquaporin‑1 aggravates hippocampal damage in mouse traumatic brain injury models

Bo Qiu, Xinguo Li, Xiyang Sun, Yong Wang, Zhitao Jing, Xu Zhang, Yunjie Wang
Pages: 916-922
Published online on: 15 January 2014

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Article

Dexamethasone reduces ATDC5 chondrocyte cell viability by inducing autophagy

Yan Zhao, Yuan Zuo, Hongjun Huo, Yulong Xiao, Xuejun Yang, Daqi Xin
Pages: 923-927
Published online on: 23 January 2014

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Article

Foxp3 gene expression in oral lichen planus: A clinicopathological study

Lei Lei, Lihua Zhan, Weixia Tan, Shaohua Chen, Yangqiu Li, Mark Reynolds
Pages: 928-934
Published online on: 24 January 2014

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Article

Isorhamnetin suppresses colon cancer cell growth through the PI3K‑Akt‑mTOR pathway

Chuan Li, Xi Yang, Cheng Chen, Shaoxin Cai, Junbo Hu
Pages: 935-940
Published online on: 07 January 2014

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Article

miR‑224 promotes colorectal cancer cells proliferation via downregulation of P21WAF1/CIP1

Xiumei Zhang, Xia Zhang, Chao Liu, Ning Jia, Xinyu Li, Jianying Xiao
Pages: 941-946
Published online on: 15 January 2014

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Article

Neuroprotective effects of orientin on hydrogen peroxide‑induced apoptosis in SH‑SY5Y cells

Benjamin Ngee Tiing Law, Anna Pick Kiong Ling, Rhun Yian Koh, Soi Moi Chye, Ying Pei Wong
Pages: 947-954
Published online on: 24 December 2013

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Article

Production of transgenic mice expressing tumor virus A under ovarian‑specific promoter 1 control using testis‑mediated gene transfer

Xinhua Chen, Zujuan Zhang, Xiaohong Chang, Yidong Niu, Heng Cui
Pages: 955-960
Published online on: 20 December 2013

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Article

Urine tenascin‑C is an independent risk factor for bladder cancer patients

Zhenfeng Guan, Jin Zeng, Zhiqiang Wang, Hongjun Xie, Chuan Lv, Zhenkun Ma, Shan Xu, Xinyang Wang, Dalin He, Lei Li
Pages: 961-966
Published online on: 18 December 2013

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Article

Expression and DNA methylation status of microRNA-375 in patients with type 2 diabetes mellitus

Kan Sun, Xiangyun Chang, Liang Yin, Jun Li, Ting Zhou, Chen Zhang, Xuan Chen
Pages: 967-972
Published online on: 18 December 2013

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Article

β-catenin deacetylation is essential for WNT‑induced proliferation of breast cancer cells

Shao-Hua Wang, Ning Li, Yao Wei, Qiu-Rong Li, Ze-Ping Yu
Pages: 973-978
Published online on: 08 January 2014

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Article

Effect of intervention in the diacylglycerol‑protein kinase C signaling pathway on JNK1 expression and its downstream signaling in diabetic cardiomyopathy

Xiaoliang Liu, Fang Qi, Wei Wu
Pages: 979-984
Published online on: 17 January 2014

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Article

P‑glycoprotein inhibition increases the transport of dauricine across the blood‑brain barrier

Pei‑Liang Dong, Hua Han, Tian‑Yu Zhang, Bingyou Yang, Qiu‑Hong Wang, Gao‑Wa Eerdun
Pages: 985-988
Published online on: 27 December 2013

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Article

Ginsenoside Rg1 reduces toxicity of fine particulate matter on human alveolar epithelial cells: A preliminary observation

Zhi‑Guo Zhang, Xu‑Yan Niu, Xiao‑Juan He, Jun Shu
Pages: 989-992
Published online on: 17 December 2013

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Article

α-eleostearic acid inhibits growth and induces apoptosis in breast cancer cells via HER2/HER3 signaling

Ren-Jie Zhuo, Feng Wang, Xiao-Hong Zhang, Jin‑Jie Zhang, Jin Xu, Wei Dong, Zu-Quan Zou
Pages: 993-998
Published online on: 13 January 2014

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Article

Recombinant lentivirus targeting the pleotrophin gene reduces pleotrophin protein expression in pancreatic cancer cells and inhibits neurite outgrowth of dorsal root ganglion neurons

Jun Yao, Wen-Yao Li, Shuo-Guo Li, Xiao-Shan Feng, She-Gan Gao
Pages: 999-1004
Published online on: 24 January 2014

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Article

Effects of azathioprine and infliximab on mesenchymal stem cells derived from the bone marrow of rats in vitro

Hua‑Rong Huang, Hui Zan, Ying Lin, Ying‑Qiang Zhong
Pages: 1005-1012
Published online on: 17 January 2014

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Article

Placental leptin gene methylation and macrosomia during normal pregnancy

Xinyun Xu, Xinjun Yang, Ziwei Liu, Kele Wu, Zheng Liu, Chong Lin, Yuhuan Wang, Hongtao Yan
Pages: 1013-1018
Published online on: 22 January 2014

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Article

Exogenous activation of LKB1/AMPK signaling induces G1 arrest in cells with endogenous LKB1 expression

Xiaoyan Liang, Pilong Wang, Qing Gao, Xiaohong Tao
Pages: 1019-1024
Published online on: 23 January 2014

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Article

Antitumor activity of CDA‑Ⅱ, a urinary preparation, on human multiple myeloma cell lines via the mitochondrial pathway

Min Yang, Jian Huang, Qiu‑Ling Ma, Gai‑Xiang Xu, Jie Jin
Pages: 1025-1031
Published online on: 22 January 2014

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Article

Gankyrin is essential for hypoxia enhanced metastatic potential in breast cancer cells

Liucun Gao, Huahong Xie, Lihou Dong, Jia Zou, Jie Fu, Xin Gao, Lun Ou, Shensi Xiang, Haifeng Song
Pages: 1032-1036
Published online on: 12 December 2013

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Article

Dendroaspis natriuretic peptide is degraded by a metalloproteinase in the rat kidney

Soo Mi Kim, Sun Young Kim, Suhn Hee Kim, Sung Zoo Kim
Pages: 1037-1043
Published online on: 17 December 2013

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Article

Vascular endothelial growth factor polymorphisms affect gene expression and tumor aggressiveness in patients with breast cancer

Doonyapat Sa-Nguanraksa, Suwattanee Kooptiwut, Tuenjai Chuangsuwanich, Tawatchai Pongpruttipan, Prida Malasit, Pornchai O-Charoenrat
Pages: 1044-1048
Published online on: 09 January 2014

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Article

Screening for key genes associated with atopic dermatitis with DNA microarrays

Zhong-Kui Zhang, Yong Yang, Shu-Rong Bai, Gui-Zhen Zhang, Tai‑Hua Liu, Zhou Zhou, Chun-Mei Wang, Li-Jun Tang, Jun Wang, Si-Xian He
Pages: 1049-1055
Published online on: 21 January 2014

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Article

Angiotensin II promotes the progression of human gastric cancer

Ming-Min Huang, Ai-Bin Guo, Jun-Feng Sun, Xiao-Lin Chen, Zhen-Yu Yin
Pages: 1056-1060
Published online on: 10 January 2014

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Article

Effects of methanolic extract form Fuzhuan brick-tea on hydrogen peroxide-induced oxidative stress in human intestinal epithelial adenocarcinoma Caco-2 cells

Jia-Le Song, Yang Gao
Pages: 1061-1067
Published online on: 07 January 2014

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Article

Transmembrane protein with unknown function 16A overexpression promotes glioma formation through the nuclear factor‑κB signaling pathway

Jun Liu, Yu Liu, Yingang Ren, Li Kang, Lihua Zhang
Pages: 1068-1074
Published online on: 08 January 2014

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Article

Promoter methylation‑associated silencing of p27kip1 gene with metastasis in esophageal squamous cell carcinoma

Yang Ling, Changsong Zhang, Yun Xu, Jing Zhu, Changtai Zhu, Mingzhu Lu, Yongping Liu, Tianbao Zhou
Pages: 1075-1079
Published online on: 08 January 2014

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Article

Facile synthesis and characterization of polyethylenimine-coated Fe3O4 superparamagnetic nanoparticles for cancer cell separation

Wei Lu, Min Ling, Min Jia, Ping Huang, Chengkui Li, Biao Yan
Pages: 1080-1084
Published online on: 20 January 2014

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Article

Epigallocatechin‑3‑gallate inhibits the proliferation and migration of human ovarian carcinoma cells by modulating p38 kinase and matrix metalloproteinase‑2

Feng Wang, Zhiwei Chang, Qingxia Fan, Liuxing Wang
Pages: 1085-1089
Published online on: 22 January 2014

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Journal Cover
January-2026 Volume 33 Issue 1

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Journal Metrics

Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

Review Open Access

Non‑coding RNAs in epithelial‑mesenchymal transition of renal cell carcinoma (Review)

Ziqiao Liu, Hanshen Zhou, Junxiao Shen, Yiming Qi, Xuke Gong, Cheng Zhang
Article Number: 51
Published online on: 24 November 2025

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Article Open Access

FOXJ3 drives mesenchymal stem cell osteogenic differentiation via the Wnt/β‑catenin pathway: A novel regulator implicated in osteoporosis

Hongwei Xiao, Jianfeng Li, Wei Huang, Yi Qin
Article Number: 50
Published online on: 21 November 2025

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Article Open Access

NEDD4 regulates VEGF signaling and mTOR to promote angiogenesis and the cell cycle in steroid‑induced osteonecrosis of the femoral head

Jian Li, Dong Zhen, Yuhuan Qin, Caifen Guo
Article Number: 49
Published online on: 21 November 2025

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Article Open Access

Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway

Chih-Hsuan Hsia, Chun-Ming Yang, Chao-Chien Chang, Ting-Lin Yen, Arief Gunawan Darmanto, Chi-Chang Huang, Joen-Rong Sheu
Article Number: 48
Published online on: 21 November 2025

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Review Open Access

Research progress on molecular therapy for glaucoma (Review)

Weiwei Wang, Gangwei Cheng, Qi Zhou, Sheng Wang, Linyi Zhang
Article Number: 47
Published online on: 21 November 2025

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Article Open Access

Natural compounds for the treatment of rheumatoid arthritis based on the ‘gut‑joint axis’ (Review)

Wenjie Hu, Rui Li, Zhongming Zhang
Article Number: 46
Published online on: 20 November 2025

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Article Open Access

TGM1 as a novel signature gene in psoriasis identified by integrative bioinformatics and experimental validation

Pan Guo, Mengke Sun, Jingyu Zhang, Qianshu Yuan, Hong Cui, Junkai Huang, Jing Luo, Qianyu Zhu, Bingxin Zhang, Lizhi Hu
Article Number: 45
Published online on: 20 November 2025

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Article Open Access

CDK1‑induced regulation of p53 phosphorylation at Ser315 mediates cell cycle arrest and apoptosis of macrophages infected with clinical isolates of Mycobacterium tuberculosis

Banghao Sun, Zhenyu Zhao, Qingyu Meng, Luya Pu, Xingyu Jiang, Shuai Li, Fadi Cao, Fan Li
Article Number: 44
Published online on: 20 November 2025

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Article Open Access

High‑intensity exercise training inhibits excessive autophagy in the hyperlipidemic myocardium of ApoE‑/‑ mice via the NAD+‑mediated SIRT1/MFN2 pathway

Shan Gao, Wei Yao, Jin Yang, Yujie Liu, Zuowei Pei
Article Number: 43
Published online on: 18 November 2025

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Correction Open Access

[Corrigendum] Protective effects of metformin against myocardial ischemia‑reperfusion injury via AMPK‑dependent suppression of NOX4

Yan Shi, Shu-Ai Hou
Article Number: 42
Published online on: 17 November 2025

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Article Open Access

Apelin promotes RANKL‑mediated osteoclastogenesis by activating MAPK and NF‑κB pathways

Yu-Han Wang, Yu-Ying Wu, Chun-Hao Tsai, Yi-Chin Fong, Chih-Yuan Ko, Hsien-Te Chen, Yat-Yin Law, Chih-Hsin Tang
Article Number: 41
Published online on: 12 November 2025

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Article Open Access

Identification of multimorbidity hub genes for knee osteoarthritis-atherosclerosis and potential clinical applications

Qingyuan Kang, Ping Yuan, Peisen Xie, Wentao Xiao, Liguang Dong, Zhenpeng Guan, Keshi Zhang
Article Number: 40
Published online on: 12 November 2025

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Article Open Access

CTSB mediates oxidative stress and intestinal epithelial barrier disruption in intestinal ischemia‑reperfusion injury

Shuang He, Lei Wang, Zhe Wang, Shiyong Yu, Qi Zhu, Yijun Xu, Yuhang Jiang, Yingxia Wu, Honggang Xiang
Article Number: 39
Published online on: 12 November 2025

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Astragaloside IV promotes the apoptosis of pancreatic cancer cells by activating endoplasmic reticulum stress through the PERK/ATF4/CHOP signaling pathway

Yijun Wang, Mengyang Zhao, Shanshan Liu, Rui Zheng, Tianhui Gao
Article Number: 38
Published online on: 11 November 2025

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[Retracted] Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a

Rui Li, Lianxin Wang
Article Number: 37
Published online on: 10 November 2025

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Migrasomes: Emerging players in intercellular communication and disease pathogenesis (Review)

Yuanliang Cao, Quan Wan, Boqi Zhou, Haixin Zeng, Xiaojie Lu
Article Number: 36
Published online on: 10 November 2025

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Diabetic keratopathy and nuclear proteins (Review)

Haiying Xu, Zhi-Liang Jiang, Yuehong Wang, Xiaoli Hou, Weixia Dong, Yanfang Chen, Qiuying Zhang, Xinying Ji, Shaoping Ji, Yalong Dang
Article Number: 35
Published online on: 10 November 2025

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Homocystinuria: Advances in metabolic and molecular therapies targeting homocysteine pathways (Review)

Ayman A. Althubity
Article Number: 34
Published online on: 10 November 2025

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Synovial chondromatosis: Novel advances in understanding the pathogenesis and in diagnostic strategies (Review)

Xingzheng Deng, Shizhang Liu, Huitong Liu
Article Number: 33
Published online on: 10 November 2025

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Protective effects of Notoginsenoside R1 on the ferroptosis of a human non‑small cell lung cancer cell line

Yuejiao Zhang, Zhongshun Mao, Yong Diao
Article Number: 32
Published online on: 06 November 2025

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Unraveling the synergy of inflammation and apoptosis in sepsis-induced acute lung injury: Insights and therapeutic perspectives (Review)

Liwen Zhang, Haoxuan Li, Dongxu Li, Qingqing Dai
Article Number: 31
Published online on: 03 November 2025

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Dihydroalterperylenol from endophytic fungus Alternaria semiverrucosa and its antitumour activity uncovered by transcriptome analysis, molecular docking and molecular dynamics simulations

Mingfei Yang, Yongzhong Lu, Long Han, Zhangjiang He, Jichuan Kang
Article Number: 30
Published online on: 03 November 2025

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[Retracted] Phosphoinositide 3‑kinase/Akt pathway is involved in pingyangmycin‑induced growth inhibition, apoptosis and reduction of invasive potential in EOMA mouse hemangioendothelioma cells

Li-Xia Peng, Ping Zhao, Hong-Sheng Zhao, Er Pan, Bin-Bin Yang, Qin Li
Article Number: 29
Published online on: 03 November 2025

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Tight junction dysfunction and cytoskeletal remodeling in Hirschsprung‑associated enterocolitis: A decade of mechanistic insights and therapeutic prospects (Review)

Shuai Li, Chen Wang, Ling Zhang, Shan Chen, Ying Zhou, Dehua Yang, Kang Li, Yuan Liu, Shuiqing Chi, Yong Wang, Lizhi Li, Shao-Tao Tang
Article Number: 28
Published online on: 03 November 2025

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Involvement of the thioredoxin system in multiple diseases: A focus on mechanisms of action in autophagy and ferroptosis (Review)

Weihua Wang, Yingdong Mou, Dunlin Lu, Shanshan Xu
Article Number: 27
Published online on: 03 November 2025

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MicroRNA‑199a‑3p suppresses non‑small cell lung cancer progression by targeting FTO to enhance m6A‑mediated downregulation of MZF1 and its transcriptional activation of CLDND1

Yuzhen Cui, Xiaoqian Li, Hongkui Zhang, Weiqiang Yuan, Enbo Zhu
Article Number: 26
Published online on: 03 November 2025

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Role of ubiquitin‑proteasome system in preeclampsia (Review)

Chang-Zhu Pei, Xiao-Xing Song, Hao Xu, Kwang-Hyun Baek
Article Number: 25
Published online on: 03 November 2025

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Schisantherin A induces ferroptosis in non‑small cell lung cancer through activation of the YAP/ACSL4/TfR signaling pathway

Wenxiang Zhu, Yeyang Chen, Xiangjian Wu, Xiaoyan Fu, Yongshi He, Yuxia Mo, Qinghua Zhu, Mingwen Tang, Zhiguang Zhai
Article Number: 24
Published online on: 03 November 2025

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The gut‑bone‑cartilage triad: Microbial regulation of the Wnt/β‑catenin signaling pathway in osteoarthritis joint remodeling (Review)

Ruipu Zhang, Liang Zhang, Bin Tian, Yiqun Wang, Xin Kang, Jiang Zheng
Article Number: 23
Published online on: 31 October 2025

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Protective impact of landiolol against acute lung injury following hemorrhagic shock and resuscitation in rats

Risa Sakamoto, Hiroko Shimizu, Ryu Nakamura, Yifu Lu, Yaqiang Li, Emiko Omori, Toru Takahashi, Hiroshi Morimatsu
Article Number: 22
Published online on: 31 October 2025

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Hidden connection: Impact of the gut microbiota on respiratory diseases in children (Review)

Yanhua Han, Yuchao Jia, Lili Chen, Mingyao Zhang
Article Number: 21
Published online on: 29 October 2025

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From renal development to pathology: An analysis of the multilevel role of insulin‑like growth factor 2 (Review)

Yuping Sun, Wenke Hao, Wei Liu, Wenxue Hu
Article Number: 20
Published online on: 29 October 2025

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[Corrigendum] Early anticoagulation therapy for severe burns complicated by inhalation injury in a rabbit model

Zhong-Hua Fu, Guang-Hua Guo, Zhen-Fang Xiong, Xincheng Liao, Ming-Zhuo Liu, Jinhua Luo
Article Number: 19
Published online on: 29 October 2025

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Mucin 2 and unfolded protein response reshape the mucus barrier in inflammatory bowel disease (Review)

Zhiwei Yuan, Zheng Xia, Liyun Ling, Jingzhe Xie, Feng Zhang
Article Number: 18
Published online on: 29 October 2025

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RING finger protein family in leukemia (Review)

Ye Wang, Yue Zhao, Jihong Zhang
Article Number: 17
Published online on: 29 October 2025

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Retinal light perception and biological rhythms: The role of light in sleep and mood from an ophthalmic perspective (Review)

Man Yuan, Hanxiang Liu, Ranjie Zhu, Yuzhen Li, Siyuan Song, Anhuai Yang
Article Number: 16
Published online on: 29 October 2025

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[Retracted] Oxymatrine‑mediated maturation of dendritic cells leads to activation of FOXP3+/CD4+ Treg cells and reversal of cisplatin‑resistance in lung cancer cells

Hui Liu, Manman Zou, Pei Li, Haifeng Wang, Xijun Lin, Jin Ye
Article Number: 15
Published online on: 27 October 2025

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Zinc finger protein 514 promotes esophageal cancer progression by enhancing cell proliferation, migration and invasion

Lin Lv, Xiaoming Sun, Houlu Zhang, Guangxu Wang, Chao Zhang, Haibo Liu, Liangming Zhu
Article Number: 14
Published online on: 24 October 2025

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Effects of zinc carnosine on bone loss in mice with diabetic osteoporosis 

Jingyuan Gao, Hao Yang, Qiangqiang Lian, Yunpeng Hu, Zhou Yang, Lei Xing, Ying Xue, Xiaoli Hou, Faming Tian, Dong Hu
Article Number: 13
Published online on: 24 October 2025

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Rapamycin improves endometriosis‑related infertility involving ovarian senescence via the PPARα/IGFBP2 pathway

Qiongwei Wu, Jiao Fan, Qingjing Sheng, Xiaoying He
Article Number: 12
Published online on: 24 October 2025

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Combining tadalafil and hyperbaric oxygen therapy protects against ovarian ischemia‑reperfusion damage in rats

Mehmet Akif Baktir, Mustafa Ermis, Esra Balcioglu, Betul Yalcin, Enes Karaman, Ahmet Cumaoglu
Article Number: 11
Published online on: 23 October 2025

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Liquid‑liquid phase separation of PHLDB2 promotes oral squamous cell carcinoma metastasis through regulating epithelial mesenchymal transition and PIK3CA expression

Kunyi Chen, Yuhong Wang, Jianing Cui, Qianrui Liu, Xiaoyong Liu, Wenjin Wang, Jinsong Hou
Article Number: 10
Published online on: 22 October 2025

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Mitochondrial gatekeeper in hepatocellular carcinoma: Unraveling the multifaceted roles of VDAC in metabolic reprogramming, apoptosis evasion and therapeutic innovation (Review)

Jie Wang, Yu Liang, Xiaotao Jia, Xinmao Yang, Danning Shi, Yuanchun Wang, Yanfang Pan
Article Number: 9
Published online on: 21 October 2025

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[Retracted] Knockdown of ubiquitin‑specific protease 51 attenuates cisplatin resistance in lung cancer through ubiquitination of zinc‑finger E‑box binding homeobox 1

Feng Zhou, Chunling Du, Donghui Xu, Jinchang Lu, Lei Zhou, Chaomin Wu, Bo Wu, Jianan Huang
Article Number: 8
Published online on: 20 October 2025

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Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury

Pengyu Zhou, Lu Li, Yu Cao, Jiahao Chen, Chuyin Chen, Xiangsheng Zhang, Jiurong Chen, Yingdong Deng, Ziqiang Lin, Yupei Lai, Suo Wang, Simin Tang, Wenqi Zhang, Peng Sun, Jun Zhou
Article Number: 7
Published online on: 15 October 2025

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R‑loops in hepatocellular carcinoma: Bridging genomic instability and therapeutic opportunity (Review)

Ching-Hua Hsieh, Yueh-Wei Liu, Pei-Chin Chuang
Article Number: 6
Published online on: 15 October 2025

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Role and relevance of exosome-mediated epigenetic regulation in the pathogenesis, diagnosis and treatment of 
cardiovascular diseases (Review)

Yishuo Zhang, Shanshan Zhang, Yijing Li, Wenqi Jin, Liya Zhou, Jing Lu
Article Number: 5
Published online on: 15 October 2025

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PLIN5 deficiency ameliorates metabolic dysfunction‑associated fatty liver disease by inhibiting ferroptosis

Ya Li, Xiaohan Wang, Xuecui Yin, Xiaohui Zhu, Weiqi Cui, Lin Dong, Yu Xia, Ying Wang, Liu Liu, Pengyuan Zheng, Youcai Tang
Article Number: 4
Published online on: 14 October 2025

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Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review)

Junmin Wang, Mengxing Cao, Shen Li, Wen Pei, Jing Li, Zhen Wang
Article Number: 3
Published online on: 14 October 2025

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MALT1 inhibition by MI‑2 suppresses epithelial‑to‑mesenchymal transition and fibrosis by inactivating the NF‑κB pathway in high glucose‑treated HK‑2 cells

Yating Lan, Jian Ma, Huijun Chen, Chaohong Lan, Na Zhao
Article Number: 2
Published online on: 14 October 2025

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[Retracted] Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms

Xinliang Zhang, Shimin Dong, Yanjun Qin, Xiaohua Bian
Article Number: 1
Published online on: 14 October 2025

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February-2026 Volume 33 Issue 2

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Impact Factor: 3.5

CiteScore: 8.5

CiteScore Rank: Q1: #78/441 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 0.772

SCImago Journal Rank (SJR): 0.841

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Mitophagy and oxidative stress in chronic kidney disease (Review)

Quwu Mushuo, Yihuai Tian, Jianchun Li, Yanqin Qiu, Hui Fan, Qiongdan Hu, Qiong Zhang
Article Number: 61
Published online on: 04 December 2025

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ABCC9 knockdown attenuates isoproterenol‑induced myocardial hypertrophy by inhibiting the PI3K/AKT signaling pathway

Qian Peng, Rui Chang, Linlin Ma, Yanfei Li
Article Number: 60
Published online on: 04 December 2025

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MeCP2 suppresses ferroptosis to drive EMT in retinal pigment epithelial cells: Implications for PVR pathogenesis

Sibei Guo, Yongya Zhang, Xue Li, Xueru Zhao, Yingjuan Liang, Xiaohua Li
Article Number: 59
Published online on: 04 December 2025

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[Corrigendum] Screening for implicated genes in colorectal cancer using whole‑genome gene expression profiling

Long-Ci Sun, Hai-Xin Qian
Article Number: 58
Published online on: 04 December 2025

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Hyperoside prevents osteoporosis by activating the PI3K/AKT signaling pathway to inhibit oxidative stress and promote osteogenesis

Lirong Li, Huaidong Deng, Shabin Zhuan, Boyu Wu, Dawei Xiao
Article Number: 57
Published online on: 03 December 2025

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[Retracted] Interference with Tim‑3 protein expression attenuates the invasion of clear cell renal cell carcinoma and aggravates anoikis

Muming Yu, Bin Lu, Yancun Liu, Ying Me, Lijun Wang, Hui Li
Article Number: 56
Published online on: 01 December 2025

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Acetylshikonin induces ferroptosis via the lipid peroxidation pathway in osteosarcoma cells

Ji-Ying Chen, Guo-Shou Wang, Tsung-Ming Chang, Ju-Fang Liu
Article Number: 55
Published online on: 27 November 2025

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Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review)

Yingjie Li, Xiaoyan Fu, Meiwen Bai, Jiaqi Zhou, Jiatai Qiu, Hongxia Zhang, Shujuan Liang, Meifang Liu
Article Number: 54
Published online on: 27 November 2025

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lncRNA NEAT1 promotes the proliferation of hemangioma cells by transcriptionally activating β‑catenin via enhancing H3K18 lactylation

Li Yu, Nian Zhou, Xiao-Liang Zhang, Xue-Jing Pang, Lu Xing, Yun-Jing Pu, Li Zhang, Jing-Nan Wu, Hong Shu
Article Number: 53
Published online on: 25 November 2025

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[Retracted] MicroRNA‑206 exerts anti‑oncogenic functions in esophageal squamous cell carcinoma by suppressing the c‑Met/AKT/mTOR pathway

Jin Zhang, Xianen Fa, Qingyong Zhang
Article Number: 52
Published online on: 25 November 2025

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